data_8ET6
# 
_entry.id   8ET6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.397 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ET6         pdb_00008et6 10.2210/pdb8et6/pdb 
WWPDB D_1000268243 ?            ?                   
EMDB  EMD-28586    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2023-05-31 
2 'Structure model' 1 1 2023-07-12 
3 'Structure model' 1 2 2023-08-02 
4 'Structure model' 1 3 2024-10-23 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
3 4 'Structure model' 'Data collection'     
4 4 'Structure model' 'Structure summary'   
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation                  
2 2 'Structure model' citation_author           
3 3 'Structure model' citation                  
4 3 'Structure model' citation_author           
5 4 'Structure model' chem_comp_atom            
6 4 'Structure model' chem_comp_bond            
7 4 'Structure model' em_admin                  
8 4 'Structure model' pdbx_entry_details        
9 4 'Structure model' pdbx_modification_feature 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 3 'Structure model' '_citation.journal_volume'                     
2 3 'Structure model' '_citation.page_first'                         
3 3 'Structure model' '_citation.page_last'                          
4 3 'Structure model' '_citation_author.identifier_ORCID'            
5 4 'Structure model' '_em_admin.last_update'                        
6 4 'Structure model' '_pdbx_entry_details.has_protein_modification' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ET6 
_pdbx_database_status.recvd_initial_deposition_date   2022-10-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of the organic cation transporter 1 in the apo state' 
_pdbx_database_related.db_id          EMD-28586 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              seok-yong.lee@duke.edu 
_pdbx_contact_author.name_first         Seok-Yong 
_pdbx_contact_author.name_last          Lee 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0662-9921 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Suo, Y.'      1 0000-0003-1198-7309 
'Wright, N.J.' 2 0000-0002-7406-2015 
'Lee, S.-Y.'   3 0000-0002-0662-9921 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? US ? ? primary Nat.Struct.Mol.Biol. ? ? 1545-9985 ? ? 30 ? 1001 1011 
'Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.' 2023 ? 10.1038/s41594-023-01017-4 37291422 ? ? 
? ? ? ? ? ? ? US ? ? 1       Biorxiv              ? ? 2692-8205 ? ? ?  ? ?    ?    
'Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2.'      2023 ? 10.1101/2023.03.15.532610  36993738 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Suo, Y.'       1  ?                   
primary 'Wright, N.J.'  2  ?                   
primary 'Guterres, H.'  3  ?                   
primary 'Fedor, J.G.'   4  ?                   
primary 'Butay, K.J.'   5  ?                   
primary 'Borgnia, M.J.' 6  ?                   
primary 'Im, W.'        7  ?                   
primary 'Lee, S.Y.'     8  ?                   
1       'Suo, Y.'       9  ?                   
1       'Wright, N.J.'  10 0000-0002-7406-2015 
1       'Guterres, H.'  11 0000-0001-7683-8385 
1       'Fedor, J.G.'   12 0000-0003-3660-3818 
1       'Butay, K.J.'   13 0000-0001-8895-5052 
1       'Borgnia, M.J.' 14 0000-0001-9159-1413 
1       'Im, W.'        15 0000-0001-5642-6041 
1       'Lee, S.Y.'     16 0000-0002-0662-9921 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man OCT1                                                                                      61299.562 1 ? ? ? ? 
2 branched man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPTVDDVLEQVGEFGWFQKQAFLTLCLLSAAFAPIYVGIVFLGFTPDHRCRSPGVAELSQRCGWSLAEELNYTVPGLGAA
GEAFPRQCRRYEVDWNQSALSCVDPLASLAANRSHLPLGPCQHGWVYDTPGSSIVTEFNLVCADSWKVDLFQSCVNVGFF
LGSLGVGYIADRFGRKLCLLATTLISAVSGVLMAVAPDYTSMLLFRLLQGLVSKGSWMSGYTLITEFVGSGYRRTVAILY
QMAFTVGLVLLSGVAYAIPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTQAIKIMDHIAQKNGKLPPADLKML
SLKEDSTEKLSPSFADLFRTPQLRKHTFILMYLWFTSSVLYQGLIMHMGATGGNLYLDFFYSALVEFPAAFIILVTIDRV
GRIYPLAVSNLVAGAACLIMIFISQDLHWLNITVACVGRMGITIVFQMVCLVNAELYPTFIRNLGVMVCSSLCDLGGIIT
PFLVFRLMEVWQGLPLILFTVVGLVAGGMTLLLPETKGVALPETIEDAENLGRKAKPKENTIYLQVQTSELPGT
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPTVDDVLEQVGEFGWFQKQAFLTLCLLSAAFAPIYVGIVFLGFTPDHRCRSPGVAELSQRCGWSLAEELNYTVPGLGAA
GEAFPRQCRRYEVDWNQSALSCVDPLASLAANRSHLPLGPCQHGWVYDTPGSSIVTEFNLVCADSWKVDLFQSCVNVGFF
LGSLGVGYIADRFGRKLCLLATTLISAVSGVLMAVAPDYTSMLLFRLLQGLVSKGSWMSGYTLITEFVGSGYRRTVAILY
QMAFTVGLVLLSGVAYAIPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTQAIKIMDHIAQKNGKLPPADLKML
SLKEDSTEKLSPSFADLFRTPQLRKHTFILMYLWFTSSVLYQGLIMHMGATGGNLYLDFFYSALVEFPAAFIILVTIDRV
GRIYPLAVSNLVAGAACLIMIFISQDLHWLNITVACVGRMGITIVFQMVCLVNAELYPTFIRNLGVMVCSSLCDLGGIIT
PFLVFRLMEVWQGLPLILFTVVGLVAGGMTLLLPETKGVALPETIEDAENLGRKAKPKENTIYLQVQTSELPGT
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   THR n 
1 4   VAL n 
1 5   ASP n 
1 6   ASP n 
1 7   VAL n 
1 8   LEU n 
1 9   GLU n 
1 10  GLN n 
1 11  VAL n 
1 12  GLY n 
1 13  GLU n 
1 14  PHE n 
1 15  GLY n 
1 16  TRP n 
1 17  PHE n 
1 18  GLN n 
1 19  LYS n 
1 20  GLN n 
1 21  ALA n 
1 22  PHE n 
1 23  LEU n 
1 24  THR n 
1 25  LEU n 
1 26  CYS n 
1 27  LEU n 
1 28  LEU n 
1 29  SER n 
1 30  ALA n 
1 31  ALA n 
1 32  PHE n 
1 33  ALA n 
1 34  PRO n 
1 35  ILE n 
1 36  TYR n 
1 37  VAL n 
1 38  GLY n 
1 39  ILE n 
1 40  VAL n 
1 41  PHE n 
1 42  LEU n 
1 43  GLY n 
1 44  PHE n 
1 45  THR n 
1 46  PRO n 
1 47  ASP n 
1 48  HIS n 
1 49  ARG n 
1 50  CYS n 
1 51  ARG n 
1 52  SER n 
1 53  PRO n 
1 54  GLY n 
1 55  VAL n 
1 56  ALA n 
1 57  GLU n 
1 58  LEU n 
1 59  SER n 
1 60  GLN n 
1 61  ARG n 
1 62  CYS n 
1 63  GLY n 
1 64  TRP n 
1 65  SER n 
1 66  LEU n 
1 67  ALA n 
1 68  GLU n 
1 69  GLU n 
1 70  LEU n 
1 71  ASN n 
1 72  TYR n 
1 73  THR n 
1 74  VAL n 
1 75  PRO n 
1 76  GLY n 
1 77  LEU n 
1 78  GLY n 
1 79  ALA n 
1 80  ALA n 
1 81  GLY n 
1 82  GLU n 
1 83  ALA n 
1 84  PHE n 
1 85  PRO n 
1 86  ARG n 
1 87  GLN n 
1 88  CYS n 
1 89  ARG n 
1 90  ARG n 
1 91  TYR n 
1 92  GLU n 
1 93  VAL n 
1 94  ASP n 
1 95  TRP n 
1 96  ASN n 
1 97  GLN n 
1 98  SER n 
1 99  ALA n 
1 100 LEU n 
1 101 SER n 
1 102 CYS n 
1 103 VAL n 
1 104 ASP n 
1 105 PRO n 
1 106 LEU n 
1 107 ALA n 
1 108 SER n 
1 109 LEU n 
1 110 ALA n 
1 111 ALA n 
1 112 ASN n 
1 113 ARG n 
1 114 SER n 
1 115 HIS n 
1 116 LEU n 
1 117 PRO n 
1 118 LEU n 
1 119 GLY n 
1 120 PRO n 
1 121 CYS n 
1 122 GLN n 
1 123 HIS n 
1 124 GLY n 
1 125 TRP n 
1 126 VAL n 
1 127 TYR n 
1 128 ASP n 
1 129 THR n 
1 130 PRO n 
1 131 GLY n 
1 132 SER n 
1 133 SER n 
1 134 ILE n 
1 135 VAL n 
1 136 THR n 
1 137 GLU n 
1 138 PHE n 
1 139 ASN n 
1 140 LEU n 
1 141 VAL n 
1 142 CYS n 
1 143 ALA n 
1 144 ASP n 
1 145 SER n 
1 146 TRP n 
1 147 LYS n 
1 148 VAL n 
1 149 ASP n 
1 150 LEU n 
1 151 PHE n 
1 152 GLN n 
1 153 SER n 
1 154 CYS n 
1 155 VAL n 
1 156 ASN n 
1 157 VAL n 
1 158 GLY n 
1 159 PHE n 
1 160 PHE n 
1 161 LEU n 
1 162 GLY n 
1 163 SER n 
1 164 LEU n 
1 165 GLY n 
1 166 VAL n 
1 167 GLY n 
1 168 TYR n 
1 169 ILE n 
1 170 ALA n 
1 171 ASP n 
1 172 ARG n 
1 173 PHE n 
1 174 GLY n 
1 175 ARG n 
1 176 LYS n 
1 177 LEU n 
1 178 CYS n 
1 179 LEU n 
1 180 LEU n 
1 181 ALA n 
1 182 THR n 
1 183 THR n 
1 184 LEU n 
1 185 ILE n 
1 186 SER n 
1 187 ALA n 
1 188 VAL n 
1 189 SER n 
1 190 GLY n 
1 191 VAL n 
1 192 LEU n 
1 193 MET n 
1 194 ALA n 
1 195 VAL n 
1 196 ALA n 
1 197 PRO n 
1 198 ASP n 
1 199 TYR n 
1 200 THR n 
1 201 SER n 
1 202 MET n 
1 203 LEU n 
1 204 LEU n 
1 205 PHE n 
1 206 ARG n 
1 207 LEU n 
1 208 LEU n 
1 209 GLN n 
1 210 GLY n 
1 211 LEU n 
1 212 VAL n 
1 213 SER n 
1 214 LYS n 
1 215 GLY n 
1 216 SER n 
1 217 TRP n 
1 218 MET n 
1 219 SER n 
1 220 GLY n 
1 221 TYR n 
1 222 THR n 
1 223 LEU n 
1 224 ILE n 
1 225 THR n 
1 226 GLU n 
1 227 PHE n 
1 228 VAL n 
1 229 GLY n 
1 230 SER n 
1 231 GLY n 
1 232 TYR n 
1 233 ARG n 
1 234 ARG n 
1 235 THR n 
1 236 VAL n 
1 237 ALA n 
1 238 ILE n 
1 239 LEU n 
1 240 TYR n 
1 241 GLN n 
1 242 MET n 
1 243 ALA n 
1 244 PHE n 
1 245 THR n 
1 246 VAL n 
1 247 GLY n 
1 248 LEU n 
1 249 VAL n 
1 250 LEU n 
1 251 LEU n 
1 252 SER n 
1 253 GLY n 
1 254 VAL n 
1 255 ALA n 
1 256 TYR n 
1 257 ALA n 
1 258 ILE n 
1 259 PRO n 
1 260 HIS n 
1 261 TRP n 
1 262 ARG n 
1 263 TRP n 
1 264 LEU n 
1 265 GLN n 
1 266 LEU n 
1 267 ALA n 
1 268 VAL n 
1 269 SER n 
1 270 LEU n 
1 271 PRO n 
1 272 THR n 
1 273 PHE n 
1 274 LEU n 
1 275 PHE n 
1 276 LEU n 
1 277 LEU n 
1 278 TYR n 
1 279 TYR n 
1 280 TRP n 
1 281 CYS n 
1 282 VAL n 
1 283 PRO n 
1 284 GLU n 
1 285 SER n 
1 286 PRO n 
1 287 ARG n 
1 288 TRP n 
1 289 LEU n 
1 290 LEU n 
1 291 SER n 
1 292 GLN n 
1 293 LYS n 
1 294 ARG n 
1 295 ASN n 
1 296 THR n 
1 297 GLN n 
1 298 ALA n 
1 299 ILE n 
1 300 LYS n 
1 301 ILE n 
1 302 MET n 
1 303 ASP n 
1 304 HIS n 
1 305 ILE n 
1 306 ALA n 
1 307 GLN n 
1 308 LYS n 
1 309 ASN n 
1 310 GLY n 
1 311 LYS n 
1 312 LEU n 
1 313 PRO n 
1 314 PRO n 
1 315 ALA n 
1 316 ASP n 
1 317 LEU n 
1 318 LYS n 
1 319 MET n 
1 320 LEU n 
1 321 SER n 
1 322 LEU n 
1 323 LYS n 
1 324 GLU n 
1 325 ASP n 
1 326 SER n 
1 327 THR n 
1 328 GLU n 
1 329 LYS n 
1 330 LEU n 
1 331 SER n 
1 332 PRO n 
1 333 SER n 
1 334 PHE n 
1 335 ALA n 
1 336 ASP n 
1 337 LEU n 
1 338 PHE n 
1 339 ARG n 
1 340 THR n 
1 341 PRO n 
1 342 GLN n 
1 343 LEU n 
1 344 ARG n 
1 345 LYS n 
1 346 HIS n 
1 347 THR n 
1 348 PHE n 
1 349 ILE n 
1 350 LEU n 
1 351 MET n 
1 352 TYR n 
1 353 LEU n 
1 354 TRP n 
1 355 PHE n 
1 356 THR n 
1 357 SER n 
1 358 SER n 
1 359 VAL n 
1 360 LEU n 
1 361 TYR n 
1 362 GLN n 
1 363 GLY n 
1 364 LEU n 
1 365 ILE n 
1 366 MET n 
1 367 HIS n 
1 368 MET n 
1 369 GLY n 
1 370 ALA n 
1 371 THR n 
1 372 GLY n 
1 373 GLY n 
1 374 ASN n 
1 375 LEU n 
1 376 TYR n 
1 377 LEU n 
1 378 ASP n 
1 379 PHE n 
1 380 PHE n 
1 381 TYR n 
1 382 SER n 
1 383 ALA n 
1 384 LEU n 
1 385 VAL n 
1 386 GLU n 
1 387 PHE n 
1 388 PRO n 
1 389 ALA n 
1 390 ALA n 
1 391 PHE n 
1 392 ILE n 
1 393 ILE n 
1 394 LEU n 
1 395 VAL n 
1 396 THR n 
1 397 ILE n 
1 398 ASP n 
1 399 ARG n 
1 400 VAL n 
1 401 GLY n 
1 402 ARG n 
1 403 ILE n 
1 404 TYR n 
1 405 PRO n 
1 406 LEU n 
1 407 ALA n 
1 408 VAL n 
1 409 SER n 
1 410 ASN n 
1 411 LEU n 
1 412 VAL n 
1 413 ALA n 
1 414 GLY n 
1 415 ALA n 
1 416 ALA n 
1 417 CYS n 
1 418 LEU n 
1 419 ILE n 
1 420 MET n 
1 421 ILE n 
1 422 PHE n 
1 423 ILE n 
1 424 SER n 
1 425 GLN n 
1 426 ASP n 
1 427 LEU n 
1 428 HIS n 
1 429 TRP n 
1 430 LEU n 
1 431 ASN n 
1 432 ILE n 
1 433 THR n 
1 434 VAL n 
1 435 ALA n 
1 436 CYS n 
1 437 VAL n 
1 438 GLY n 
1 439 ARG n 
1 440 MET n 
1 441 GLY n 
1 442 ILE n 
1 443 THR n 
1 444 ILE n 
1 445 VAL n 
1 446 PHE n 
1 447 GLN n 
1 448 MET n 
1 449 VAL n 
1 450 CYS n 
1 451 LEU n 
1 452 VAL n 
1 453 ASN n 
1 454 ALA n 
1 455 GLU n 
1 456 LEU n 
1 457 TYR n 
1 458 PRO n 
1 459 THR n 
1 460 PHE n 
1 461 ILE n 
1 462 ARG n 
1 463 ASN n 
1 464 LEU n 
1 465 GLY n 
1 466 VAL n 
1 467 MET n 
1 468 VAL n 
1 469 CYS n 
1 470 SER n 
1 471 SER n 
1 472 LEU n 
1 473 CYS n 
1 474 ASP n 
1 475 LEU n 
1 476 GLY n 
1 477 GLY n 
1 478 ILE n 
1 479 ILE n 
1 480 THR n 
1 481 PRO n 
1 482 PHE n 
1 483 LEU n 
1 484 VAL n 
1 485 PHE n 
1 486 ARG n 
1 487 LEU n 
1 488 MET n 
1 489 GLU n 
1 490 VAL n 
1 491 TRP n 
1 492 GLN n 
1 493 GLY n 
1 494 LEU n 
1 495 PRO n 
1 496 LEU n 
1 497 ILE n 
1 498 LEU n 
1 499 PHE n 
1 500 THR n 
1 501 VAL n 
1 502 VAL n 
1 503 GLY n 
1 504 LEU n 
1 505 VAL n 
1 506 ALA n 
1 507 GLY n 
1 508 GLY n 
1 509 MET n 
1 510 THR n 
1 511 LEU n 
1 512 LEU n 
1 513 LEU n 
1 514 PRO n 
1 515 GLU n 
1 516 THR n 
1 517 LYS n 
1 518 GLY n 
1 519 VAL n 
1 520 ALA n 
1 521 LEU n 
1 522 PRO n 
1 523 GLU n 
1 524 THR n 
1 525 ILE n 
1 526 GLU n 
1 527 ASP n 
1 528 ALA n 
1 529 GLU n 
1 530 ASN n 
1 531 LEU n 
1 532 GLY n 
1 533 ARG n 
1 534 LYS n 
1 535 ALA n 
1 536 LYS n 
1 537 PRO n 
1 538 LYS n 
1 539 GLU n 
1 540 ASN n 
1 541 THR n 
1 542 ILE n 
1 543 TYR n 
1 544 LEU n 
1 545 GLN n 
1 546 VAL n 
1 547 GLN n 
1 548 THR n 
1 549 SER n 
1 550 GLU n 
1 551 LEU n 
1 552 PRO n 
1 553 GLY n 
1 554 THR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   554 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DGlcpNAcb1-4DGlcpNAcb1-                               'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 2 '[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}'    LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  2 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   THR 3   3   3   THR THR A . n 
A 1 4   VAL 4   4   4   VAL VAL A . n 
A 1 5   ASP 5   5   5   ASP ASP A . n 
A 1 6   ASP 6   6   6   ASP ASP A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  GLN 10  10  10  GLN GLN A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  GLU 13  13  13  GLU GLU A . n 
A 1 14  PHE 14  14  14  PHE PHE A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  TRP 16  16  16  TRP TRP A . n 
A 1 17  PHE 17  17  17  PHE PHE A . n 
A 1 18  GLN 18  18  18  GLN GLN A . n 
A 1 19  LYS 19  19  19  LYS LYS A . n 
A 1 20  GLN 20  20  20  GLN GLN A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  LEU 25  25  25  LEU LEU A . n 
A 1 26  CYS 26  26  26  CYS CYS A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  SER 29  29  29  SER SER A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  ALA 31  31  31  ALA ALA A . n 
A 1 32  PHE 32  32  32  PHE PHE A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  TYR 36  36  36  TYR TYR A . n 
A 1 37  VAL 37  37  37  VAL VAL A . n 
A 1 38  GLY 38  38  38  GLY GLY A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  VAL 40  40  40  VAL VAL A . n 
A 1 41  PHE 41  41  41  PHE PHE A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  GLY 43  43  43  GLY GLY A . n 
A 1 44  PHE 44  44  44  PHE PHE A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  ASP 47  47  47  ASP ASP A . n 
A 1 48  HIS 48  48  48  HIS HIS A . n 
A 1 49  ARG 49  49  49  ARG ARG A . n 
A 1 50  CYS 50  50  50  CYS CYS A . n 
A 1 51  ARG 51  51  51  ARG ARG A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  PRO 53  53  53  PRO PRO A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  GLU 57  57  57  GLU GLU A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  SER 59  59  59  SER SER A . n 
A 1 60  GLN 60  60  60  GLN GLN A . n 
A 1 61  ARG 61  61  61  ARG ARG A . n 
A 1 62  CYS 62  62  62  CYS CYS A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  TRP 64  64  64  TRP TRP A . n 
A 1 65  SER 65  65  65  SER SER A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  GLU 69  69  69  GLU GLU A . n 
A 1 70  LEU 70  70  70  LEU LEU A . n 
A 1 71  ASN 71  71  71  ASN ASN A . n 
A 1 72  TYR 72  72  72  TYR TYR A . n 
A 1 73  THR 73  73  73  THR THR A . n 
A 1 74  VAL 74  74  74  VAL VAL A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  GLY 76  76  76  GLY GLY A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  ALA 79  79  79  ALA ALA A . n 
A 1 80  ALA 80  80  80  ALA ALA A . n 
A 1 81  GLY 81  81  81  GLY GLY A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  ARG 86  86  86  ARG ARG A . n 
A 1 87  GLN 87  87  87  GLN GLN A . n 
A 1 88  CYS 88  88  88  CYS CYS A . n 
A 1 89  ARG 89  89  89  ARG ARG A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  GLU 92  92  92  GLU GLU A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  ASP 94  94  94  ASP ASP A . n 
A 1 95  TRP 95  95  95  TRP TRP A . n 
A 1 96  ASN 96  96  96  ASN ASN A . n 
A 1 97  GLN 97  97  97  GLN GLN A . n 
A 1 98  SER 98  98  98  SER SER A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 SER 101 101 101 SER SER A . n 
A 1 102 CYS 102 102 102 CYS CYS A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 ASP 104 104 104 ASP ASP A . n 
A 1 105 PRO 105 105 105 PRO PRO A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 ALA 107 107 107 ALA ALA A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 ALA 111 111 111 ALA ALA A . n 
A 1 112 ASN 112 112 112 ASN ASN A . n 
A 1 113 ARG 113 113 113 ARG ARG A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 HIS 115 115 115 HIS HIS A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 PRO 120 120 120 PRO PRO A . n 
A 1 121 CYS 121 121 121 CYS CYS A . n 
A 1 122 GLN 122 122 122 GLN GLN A . n 
A 1 123 HIS 123 123 123 HIS HIS A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 TRP 125 125 125 TRP TRP A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 TYR 127 127 127 TYR TYR A . n 
A 1 128 ASP 128 128 128 ASP ASP A . n 
A 1 129 THR 129 129 129 THR THR A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 ILE 134 134 134 ILE ILE A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 GLU 137 137 137 GLU GLU A . n 
A 1 138 PHE 138 138 138 PHE PHE A . n 
A 1 139 ASN 139 139 139 ASN ASN A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 CYS 142 142 142 CYS CYS A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 TRP 146 146 146 TRP TRP A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 ASP 149 149 149 ASP ASP A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 PHE 151 151 151 PHE PHE A . n 
A 1 152 GLN 152 152 152 GLN GLN A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 CYS 154 154 154 CYS CYS A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 PHE 160 160 160 PHE PHE A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 SER 163 163 163 SER SER A . n 
A 1 164 LEU 164 164 164 LEU LEU A . n 
A 1 165 GLY 165 165 165 GLY GLY A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 TYR 168 168 168 TYR TYR A . n 
A 1 169 ILE 169 169 169 ILE ILE A . n 
A 1 170 ALA 170 170 170 ALA ALA A . n 
A 1 171 ASP 171 171 171 ASP ASP A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 LYS 176 176 176 LYS LYS A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 CYS 178 178 178 CYS CYS A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 ILE 185 185 185 ILE ILE A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 MET 193 193 193 MET MET A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 ALA 196 196 196 ALA ALA A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 TYR 199 199 199 TYR TYR A . n 
A 1 200 THR 200 200 200 THR THR A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 MET 202 202 202 MET MET A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 PHE 205 205 205 PHE PHE A . n 
A 1 206 ARG 206 206 206 ARG ARG A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 SER 213 213 213 SER SER A . n 
A 1 214 LYS 214 214 214 LYS LYS A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 TRP 217 217 217 TRP TRP A . n 
A 1 218 MET 218 218 218 MET MET A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 TYR 221 221 221 TYR TYR A . n 
A 1 222 THR 222 222 222 THR THR A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 ILE 224 224 224 ILE ILE A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 GLU 226 226 226 GLU GLU A . n 
A 1 227 PHE 227 227 227 PHE PHE A . n 
A 1 228 VAL 228 228 228 VAL VAL A . n 
A 1 229 GLY 229 229 229 GLY GLY A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 TYR 232 232 232 TYR TYR A . n 
A 1 233 ARG 233 233 233 ARG ARG A . n 
A 1 234 ARG 234 234 234 ARG ARG A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 GLN 241 241 241 GLN GLN A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 THR 245 245 245 THR THR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 GLY 247 247 247 GLY GLY A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 GLY 253 253 253 GLY GLY A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 TYR 256 256 256 TYR TYR A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 PRO 259 259 259 PRO PRO A . n 
A 1 260 HIS 260 260 260 HIS HIS A . n 
A 1 261 TRP 261 261 261 TRP TRP A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 TRP 263 263 263 TRP TRP A . n 
A 1 264 LEU 264 264 264 LEU LEU A . n 
A 1 265 GLN 265 265 265 GLN GLN A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 VAL 268 268 268 VAL VAL A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 PRO 271 271 271 PRO PRO A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 PHE 273 273 273 PHE PHE A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 TYR 278 278 278 TYR TYR A . n 
A 1 279 TYR 279 279 279 TYR TYR A . n 
A 1 280 TRP 280 280 280 TRP TRP A . n 
A 1 281 CYS 281 281 281 CYS CYS A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 PRO 283 283 283 PRO PRO A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 SER 285 285 285 SER SER A . n 
A 1 286 PRO 286 286 286 PRO PRO A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 TRP 288 288 288 TRP TRP A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 GLN 292 292 292 GLN GLN A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 ASN 295 295 295 ASN ASN A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 ILE 299 299 299 ILE ILE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 MET 302 302 302 MET MET A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 HIS 304 304 304 HIS HIS A . n 
A 1 305 ILE 305 305 305 ILE ILE A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 GLN 307 307 307 GLN GLN A . n 
A 1 308 LYS 308 308 308 LYS LYS A . n 
A 1 309 ASN 309 309 309 ASN ASN A . n 
A 1 310 GLY 310 310 310 GLY GLY A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 PRO 313 313 313 PRO PRO A . n 
A 1 314 PRO 314 314 314 PRO PRO A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 ASP 316 316 316 ASP ASP A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 MET 319 319 319 MET MET A . n 
A 1 320 LEU 320 320 320 LEU LEU A . n 
A 1 321 SER 321 321 321 SER SER A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 GLU 324 324 324 GLU GLU A . n 
A 1 325 ASP 325 325 325 ASP ASP A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 GLU 328 328 328 GLU GLU A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 SER 331 331 331 SER SER A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 SER 333 333 333 SER SER A . n 
A 1 334 PHE 334 334 334 PHE PHE A . n 
A 1 335 ALA 335 335 335 ALA ALA A . n 
A 1 336 ASP 336 336 336 ASP ASP A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 PHE 338 338 338 PHE PHE A . n 
A 1 339 ARG 339 339 339 ARG ARG A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 PRO 341 341 341 PRO PRO A . n 
A 1 342 GLN 342 342 342 GLN GLN A . n 
A 1 343 LEU 343 343 343 LEU LEU A . n 
A 1 344 ARG 344 344 344 ARG ARG A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 HIS 346 346 346 HIS HIS A . n 
A 1 347 THR 347 347 347 THR THR A . n 
A 1 348 PHE 348 348 348 PHE PHE A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 LEU 350 350 350 LEU LEU A . n 
A 1 351 MET 351 351 351 MET MET A . n 
A 1 352 TYR 352 352 352 TYR TYR A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 TRP 354 354 354 TRP TRP A . n 
A 1 355 PHE 355 355 355 PHE PHE A . n 
A 1 356 THR 356 356 356 THR THR A . n 
A 1 357 SER 357 357 357 SER SER A . n 
A 1 358 SER 358 358 358 SER SER A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 TYR 361 361 361 TYR TYR A . n 
A 1 362 GLN 362 362 362 GLN GLN A . n 
A 1 363 GLY 363 363 363 GLY GLY A . n 
A 1 364 LEU 364 364 364 LEU LEU A . n 
A 1 365 ILE 365 365 365 ILE ILE A . n 
A 1 366 MET 366 366 366 MET MET A . n 
A 1 367 HIS 367 367 367 HIS HIS A . n 
A 1 368 MET 368 368 368 MET MET A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 THR 371 371 371 THR THR A . n 
A 1 372 GLY 372 372 372 GLY GLY A . n 
A 1 373 GLY 373 373 373 GLY GLY A . n 
A 1 374 ASN 374 374 374 ASN ASN A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 TYR 376 376 376 TYR TYR A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 ASP 378 378 378 ASP ASP A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 PHE 380 380 380 PHE PHE A . n 
A 1 381 TYR 381 381 381 TYR TYR A . n 
A 1 382 SER 382 382 382 SER SER A . n 
A 1 383 ALA 383 383 383 ALA ALA A . n 
A 1 384 LEU 384 384 384 LEU LEU A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 GLU 386 386 386 GLU GLU A . n 
A 1 387 PHE 387 387 387 PHE PHE A . n 
A 1 388 PRO 388 388 388 PRO PRO A . n 
A 1 389 ALA 389 389 389 ALA ALA A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 ILE 392 392 392 ILE ILE A . n 
A 1 393 ILE 393 393 393 ILE ILE A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 ILE 397 397 397 ILE ILE A . n 
A 1 398 ASP 398 398 398 ASP ASP A . n 
A 1 399 ARG 399 399 399 ARG ARG A . n 
A 1 400 VAL 400 400 400 VAL VAL A . n 
A 1 401 GLY 401 401 401 GLY GLY A . n 
A 1 402 ARG 402 402 402 ARG ARG A . n 
A 1 403 ILE 403 403 403 ILE ILE A . n 
A 1 404 TYR 404 404 404 TYR TYR A . n 
A 1 405 PRO 405 405 405 PRO PRO A . n 
A 1 406 LEU 406 406 406 LEU LEU A . n 
A 1 407 ALA 407 407 407 ALA ALA A . n 
A 1 408 VAL 408 408 408 VAL VAL A . n 
A 1 409 SER 409 409 409 SER SER A . n 
A 1 410 ASN 410 410 410 ASN ASN A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ALA 413 413 413 ALA ALA A . n 
A 1 414 GLY 414 414 414 GLY GLY A . n 
A 1 415 ALA 415 415 415 ALA ALA A . n 
A 1 416 ALA 416 416 416 ALA ALA A . n 
A 1 417 CYS 417 417 417 CYS CYS A . n 
A 1 418 LEU 418 418 418 LEU LEU A . n 
A 1 419 ILE 419 419 419 ILE ILE A . n 
A 1 420 MET 420 420 420 MET MET A . n 
A 1 421 ILE 421 421 421 ILE ILE A . n 
A 1 422 PHE 422 422 422 PHE PHE A . n 
A 1 423 ILE 423 423 423 ILE ILE A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 GLN 425 425 425 GLN GLN A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 LEU 427 427 427 LEU LEU A . n 
A 1 428 HIS 428 428 428 HIS HIS A . n 
A 1 429 TRP 429 429 429 TRP TRP A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 ASN 431 431 431 ASN ASN A . n 
A 1 432 ILE 432 432 432 ILE ILE A . n 
A 1 433 THR 433 433 433 THR THR A . n 
A 1 434 VAL 434 434 434 VAL VAL A . n 
A 1 435 ALA 435 435 435 ALA ALA A . n 
A 1 436 CYS 436 436 436 CYS CYS A . n 
A 1 437 VAL 437 437 437 VAL VAL A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 ARG 439 439 439 ARG ARG A . n 
A 1 440 MET 440 440 440 MET MET A . n 
A 1 441 GLY 441 441 441 GLY GLY A . n 
A 1 442 ILE 442 442 442 ILE ILE A . n 
A 1 443 THR 443 443 443 THR THR A . n 
A 1 444 ILE 444 444 444 ILE ILE A . n 
A 1 445 VAL 445 445 445 VAL VAL A . n 
A 1 446 PHE 446 446 446 PHE PHE A . n 
A 1 447 GLN 447 447 447 GLN GLN A . n 
A 1 448 MET 448 448 448 MET MET A . n 
A 1 449 VAL 449 449 449 VAL VAL A . n 
A 1 450 CYS 450 450 450 CYS CYS A . n 
A 1 451 LEU 451 451 451 LEU LEU A . n 
A 1 452 VAL 452 452 452 VAL VAL A . n 
A 1 453 ASN 453 453 453 ASN ASN A . n 
A 1 454 ALA 454 454 454 ALA ALA A . n 
A 1 455 GLU 455 455 455 GLU GLU A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 TYR 457 457 457 TYR TYR A . n 
A 1 458 PRO 458 458 458 PRO PRO A . n 
A 1 459 THR 459 459 459 THR THR A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 ILE 461 461 461 ILE ILE A . n 
A 1 462 ARG 462 462 462 ARG ARG A . n 
A 1 463 ASN 463 463 463 ASN ASN A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 MET 467 467 467 MET MET A . n 
A 1 468 VAL 468 468 468 VAL VAL A . n 
A 1 469 CYS 469 469 469 CYS CYS A . n 
A 1 470 SER 470 470 470 SER SER A . n 
A 1 471 SER 471 471 471 SER SER A . n 
A 1 472 LEU 472 472 472 LEU LEU A . n 
A 1 473 CYS 473 473 473 CYS CYS A . n 
A 1 474 ASP 474 474 474 ASP ASP A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 GLY 476 476 476 GLY GLY A . n 
A 1 477 GLY 477 477 477 GLY GLY A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ILE 479 479 479 ILE ILE A . n 
A 1 480 THR 480 480 480 THR THR A . n 
A 1 481 PRO 481 481 481 PRO PRO A . n 
A 1 482 PHE 482 482 482 PHE PHE A . n 
A 1 483 LEU 483 483 483 LEU LEU A . n 
A 1 484 VAL 484 484 484 VAL VAL A . n 
A 1 485 PHE 485 485 485 PHE PHE A . n 
A 1 486 ARG 486 486 486 ARG ARG A . n 
A 1 487 LEU 487 487 487 LEU LEU A . n 
A 1 488 MET 488 488 488 MET MET A . n 
A 1 489 GLU 489 489 489 GLU GLU A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
A 1 491 TRP 491 491 491 TRP TRP A . n 
A 1 492 GLN 492 492 492 GLN GLN A . n 
A 1 493 GLY 493 493 493 GLY GLY A . n 
A 1 494 LEU 494 494 494 LEU LEU A . n 
A 1 495 PRO 495 495 495 PRO PRO A . n 
A 1 496 LEU 496 496 496 LEU LEU A . n 
A 1 497 ILE 497 497 497 ILE ILE A . n 
A 1 498 LEU 498 498 498 LEU LEU A . n 
A 1 499 PHE 499 499 499 PHE PHE A . n 
A 1 500 THR 500 500 500 THR THR A . n 
A 1 501 VAL 501 501 501 VAL VAL A . n 
A 1 502 VAL 502 502 502 VAL VAL A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 LEU 504 504 504 LEU LEU A . n 
A 1 505 VAL 505 505 505 VAL VAL A . n 
A 1 506 ALA 506 506 506 ALA ALA A . n 
A 1 507 GLY 507 507 507 GLY GLY A . n 
A 1 508 GLY 508 508 508 GLY GLY A . n 
A 1 509 MET 509 509 509 MET MET A . n 
A 1 510 THR 510 510 510 THR THR A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 LEU 512 512 512 LEU LEU A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 PRO 514 514 514 PRO PRO A . n 
A 1 515 GLU 515 515 515 GLU GLU A . n 
A 1 516 THR 516 516 516 THR THR A . n 
A 1 517 LYS 517 517 517 LYS LYS A . n 
A 1 518 GLY 518 518 518 GLY GLY A . n 
A 1 519 VAL 519 519 519 VAL VAL A . n 
A 1 520 ALA 520 520 520 ALA ALA A . n 
A 1 521 LEU 521 521 521 LEU LEU A . n 
A 1 522 PRO 522 522 522 PRO PRO A . n 
A 1 523 GLU 523 523 523 GLU GLU A . n 
A 1 524 THR 524 524 524 THR THR A . n 
A 1 525 ILE 525 525 525 ILE ILE A . n 
A 1 526 GLU 526 526 526 GLU GLU A . n 
A 1 527 ASP 527 527 527 ASP ASP A . n 
A 1 528 ALA 528 528 528 ALA ALA A . n 
A 1 529 GLU 529 529 529 GLU GLU A . n 
A 1 530 ASN 530 530 530 ASN ASN A . n 
A 1 531 LEU 531 531 531 LEU LEU A . n 
A 1 532 GLY 532 532 532 GLY GLY A . n 
A 1 533 ARG 533 533 533 ARG ARG A . n 
A 1 534 LYS 534 534 ?   ?   ?   A . n 
A 1 535 ALA 535 535 ?   ?   ?   A . n 
A 1 536 LYS 536 536 ?   ?   ?   A . n 
A 1 537 PRO 537 537 ?   ?   ?   A . n 
A 1 538 LYS 538 538 ?   ?   ?   A . n 
A 1 539 GLU 539 539 ?   ?   ?   A . n 
A 1 540 ASN 540 540 ?   ?   ?   A . n 
A 1 541 THR 541 541 ?   ?   ?   A . n 
A 1 542 ILE 542 542 ?   ?   ?   A . n 
A 1 543 TYR 543 543 ?   ?   ?   A . n 
A 1 544 LEU 544 544 ?   ?   ?   A . n 
A 1 545 GLN 545 545 ?   ?   ?   A . n 
A 1 546 VAL 546 546 ?   ?   ?   A . n 
A 1 547 GLN 547 547 ?   ?   ?   A . n 
A 1 548 THR 548 548 ?   ?   ?   A . n 
A 1 549 SER 549 549 ?   ?   ?   A . n 
A 1 550 GLU 550 550 ?   ?   ?   A . n 
A 1 551 LEU 551 551 ?   ?   ?   A . n 
A 1 552 PRO 552 552 ?   ?   ?   A . n 
A 1 553 GLY 553 553 ?   ?   ?   A . n 
A 1 554 THR 554 554 ?   ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
B 2 NAG 1 B NAG 1 A NAG 534 n 
B 2 NAG 2 B NAG 2 A NAG 535 n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 57  ? CG  ? A GLU 57  CG  
2  1 Y 1 A GLU 57  ? CD  ? A GLU 57  CD  
3  1 Y 1 A GLU 57  ? OE1 ? A GLU 57  OE1 
4  1 Y 1 A GLU 57  ? OE2 ? A GLU 57  OE2 
5  1 Y 1 A GLN 60  ? CG  ? A GLN 60  CG  
6  1 Y 1 A GLN 60  ? CD  ? A GLN 60  CD  
7  1 Y 1 A GLN 60  ? OE1 ? A GLN 60  OE1 
8  1 Y 1 A GLN 60  ? NE2 ? A GLN 60  NE2 
9  1 Y 1 A GLU 82  ? CG  ? A GLU 82  CG  
10 1 Y 1 A GLU 82  ? CD  ? A GLU 82  CD  
11 1 Y 1 A GLU 82  ? OE1 ? A GLU 82  OE1 
12 1 Y 1 A GLU 82  ? OE2 ? A GLU 82  OE2 
13 1 Y 1 A GLU 92  ? CG  ? A GLU 92  CG  
14 1 Y 1 A GLU 92  ? CD  ? A GLU 92  CD  
15 1 Y 1 A GLU 92  ? OE1 ? A GLU 92  OE1 
16 1 Y 1 A GLU 92  ? OE2 ? A GLU 92  OE2 
17 1 Y 1 A ASP 94  ? CG  ? A ASP 94  CG  
18 1 Y 1 A ASP 94  ? OD1 ? A ASP 94  OD1 
19 1 Y 1 A ASP 94  ? OD2 ? A ASP 94  OD2 
20 1 Y 1 A GLN 97  ? CG  ? A GLN 97  CG  
21 1 Y 1 A GLN 97  ? CD  ? A GLN 97  CD  
22 1 Y 1 A GLN 97  ? OE1 ? A GLN 97  OE1 
23 1 Y 1 A GLN 97  ? NE2 ? A GLN 97  NE2 
24 1 Y 1 A SER 101 ? OG  ? A SER 101 OG  
25 1 Y 1 A LEU 116 ? CG  ? A LEU 116 CG  
26 1 Y 1 A LEU 116 ? CD1 ? A LEU 116 CD1 
27 1 Y 1 A LEU 116 ? CD2 ? A LEU 116 CD2 
28 1 Y 1 A ASP 316 ? CG  ? A ASP 316 CG  
29 1 Y 1 A ASP 316 ? OD1 ? A ASP 316 OD1 
30 1 Y 1 A ASP 316 ? OD2 ? A ASP 316 OD2 
31 1 Y 1 A MET 319 ? CG  ? A MET 319 CG  
32 1 Y 1 A MET 319 ? SD  ? A MET 319 SD  
33 1 Y 1 A MET 319 ? CE  ? A MET 319 CE  
34 1 Y 1 A LYS 323 ? CG  ? A LYS 323 CG  
35 1 Y 1 A LYS 323 ? CD  ? A LYS 323 CD  
36 1 Y 1 A LYS 323 ? CE  ? A LYS 323 CE  
37 1 Y 1 A LYS 323 ? NZ  ? A LYS 323 NZ  
38 1 Y 1 A GLU 324 ? CG  ? A GLU 324 CG  
39 1 Y 1 A GLU 324 ? CD  ? A GLU 324 CD  
40 1 Y 1 A GLU 324 ? OE1 ? A GLU 324 OE1 
41 1 Y 1 A GLU 324 ? OE2 ? A GLU 324 OE2 
42 1 Y 1 A ASP 325 ? CG  ? A ASP 325 CG  
43 1 Y 1 A ASP 325 ? OD1 ? A ASP 325 OD1 
44 1 Y 1 A ASP 325 ? OD2 ? A ASP 325 OD2 
45 1 Y 1 A THR 327 ? OG1 ? A THR 327 OG1 
46 1 Y 1 A THR 327 ? CG2 ? A THR 327 CG2 
47 1 Y 1 A GLU 328 ? CG  ? A GLU 328 CG  
48 1 Y 1 A GLU 328 ? CD  ? A GLU 328 CD  
49 1 Y 1 A GLU 328 ? OE1 ? A GLU 328 OE1 
50 1 Y 1 A GLU 328 ? OE2 ? A GLU 328 OE2 
51 1 Y 1 A LYS 329 ? CG  ? A LYS 329 CG  
52 1 Y 1 A LYS 329 ? CD  ? A LYS 329 CD  
53 1 Y 1 A LYS 329 ? CE  ? A LYS 329 CE  
54 1 Y 1 A LYS 329 ? NZ  ? A LYS 329 NZ  
55 1 Y 1 A THR 371 ? OG1 ? A THR 371 OG1 
56 1 Y 1 A THR 371 ? CG2 ? A THR 371 CG2 
57 1 Y 1 A ILE 421 ? CG1 ? A ILE 421 CG1 
58 1 Y 1 A ILE 421 ? CG2 ? A ILE 421 CG2 
59 1 Y 1 A ILE 421 ? CD1 ? A ILE 421 CD1 
60 1 Y 1 A GLN 425 ? CG  ? A GLN 425 CG  
61 1 Y 1 A GLN 425 ? CD  ? A GLN 425 CD  
62 1 Y 1 A GLN 425 ? OE1 ? A GLN 425 OE1 
63 1 Y 1 A GLN 425 ? NE2 ? A GLN 425 NE2 
64 1 Y 1 A LEU 427 ? CG  ? A LEU 427 CG  
65 1 Y 1 A LEU 427 ? CD1 ? A LEU 427 CD1 
66 1 Y 1 A LEU 427 ? CD2 ? A LEU 427 CD2 
67 1 Y 1 A GLU 489 ? CG  ? A GLU 489 CG  
68 1 Y 1 A GLU 489 ? CD  ? A GLU 489 CD  
69 1 Y 1 A GLU 489 ? OE1 ? A GLU 489 OE1 
70 1 Y 1 A GLU 489 ? OE2 ? A GLU 489 OE2 
71 1 Y 1 A VAL 490 ? CG1 ? A VAL 490 CG1 
72 1 Y 1 A VAL 490 ? CG2 ? A VAL 490 CG2 
73 1 Y 1 A GLU 529 ? CG  ? A GLU 529 CG  
74 1 Y 1 A GLU 529 ? CD  ? A GLU 529 CD  
75 1 Y 1 A GLU 529 ? OE1 ? A GLU 529 OE1 
76 1 Y 1 A GLU 529 ? OE2 ? A GLU 529 OE2 
77 1 Y 1 A ARG 533 ? CG  ? A ARG 533 CG  
78 1 Y 1 A ARG 533 ? CD  ? A ARG 533 CD  
79 1 Y 1 A ARG 533 ? NE  ? A ARG 533 NE  
80 1 Y 1 A ARG 533 ? CZ  ? A ARG 533 CZ  
81 1 Y 1 A ARG 533 ? NH1 ? A ARG 533 NH1 
82 1 Y 1 A ARG 533 ? NH2 ? A ARG 533 NH2 
# 
_software.citation_id            ? 
_software.classification         refinement 
_software.compiler_name          ? 
_software.compiler_version       ? 
_software.contact_author         ? 
_software.contact_author_email   ? 
_software.date                   ? 
_software.description            ? 
_software.dependencies           ? 
_software.hardware               ? 
_software.language               ? 
_software.location               ? 
_software.mods                   ? 
_software.name                   PHENIX 
_software.os                     ? 
_software.os_version             ? 
_software.type                   ? 
_software.version                1.19.2_4158: 
_software.pdbx_ordinal           1 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ET6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ET6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ET6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8ET6 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 4183 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.494  ? 5711 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 11.594 ? 1437 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.037  ? 673  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 705  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8ET6 
_struct.title                        'Cryo-EM structure of the organic cation transporter 1 in the apo state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ET6 
_struct_keywords.text            'organic cation, transport, membrane protein, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8ET6 
_struct_ref.pdbx_db_accession          8ET6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8ET6 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 554 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             8ET6 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  554 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       554 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 3   ? VAL A 11  ? THR A 3   VAL A 11  1 ? 9  
HELX_P HELX_P2  AA2 GLY A 15  ? ALA A 30  ? GLY A 15  ALA A 30  1 ? 16 
HELX_P HELX_P3  AA3 ALA A 31  ? GLY A 38  ? ALA A 31  GLY A 38  1 ? 8  
HELX_P HELX_P4  AA4 SER A 52  ? CYS A 62  ? SER A 52  CYS A 62  1 ? 11 
HELX_P HELX_P5  AA5 SER A 65  ? VAL A 74  ? SER A 65  VAL A 74  1 ? 10 
HELX_P HELX_P6  AA6 ALA A 83  ? ARG A 89  ? ALA A 83  ARG A 89  1 ? 7  
HELX_P HELX_P7  AA7 LEU A 106 ? ALA A 111 ? LEU A 106 ALA A 111 1 ? 6  
HELX_P HELX_P8  AA8 SER A 133 ? ASN A 139 ? SER A 133 ASN A 139 1 ? 7  
HELX_P HELX_P9  AA9 SER A 145 ? PHE A 173 ? SER A 145 PHE A 173 1 ? 29 
HELX_P HELX_P10 AB1 GLY A 174 ? ALA A 194 ? GLY A 174 ALA A 194 1 ? 21 
HELX_P HELX_P11 AB2 ASP A 198 ? VAL A 228 ? ASP A 198 VAL A 228 1 ? 31 
HELX_P HELX_P12 AB3 TYR A 232 ? ILE A 258 ? TYR A 232 ILE A 258 1 ? 27 
HELX_P HELX_P13 AB4 HIS A 260 ? LEU A 276 ? HIS A 260 LEU A 276 1 ? 17 
HELX_P HELX_P14 AB5 LEU A 277 ? TYR A 279 ? LEU A 277 TYR A 279 5 ? 3  
HELX_P HELX_P15 AB6 SER A 285 ? GLN A 292 ? SER A 285 GLN A 292 1 ? 8  
HELX_P HELX_P16 AB7 ARG A 294 ? GLY A 310 ? ARG A 294 GLY A 310 1 ? 17 
HELX_P HELX_P17 AB8 PRO A 314 ? LEU A 320 ? PRO A 314 LEU A 320 5 ? 7  
HELX_P HELX_P18 AB9 PHE A 334 ? ARG A 339 ? PHE A 334 ARG A 339 5 ? 6  
HELX_P HELX_P19 AC1 THR A 340 ? HIS A 367 ? THR A 340 HIS A 367 1 ? 28 
HELX_P HELX_P20 AC2 ASN A 374 ? VAL A 385 ? ASN A 374 VAL A 385 1 ? 12 
HELX_P HELX_P21 AC3 GLU A 386 ? GLY A 401 ? GLU A 386 GLY A 401 1 ? 16 
HELX_P HELX_P22 AC4 ARG A 402 ? ILE A 423 ? ARG A 402 ILE A 423 1 ? 22 
HELX_P HELX_P23 AC5 HIS A 428 ? TYR A 457 ? HIS A 428 TYR A 457 1 ? 30 
HELX_P HELX_P24 AC6 PRO A 458 ? PHE A 460 ? PRO A 458 PHE A 460 5 ? 3  
HELX_P HELX_P25 AC7 ILE A 461 ? TRP A 491 ? ILE A 461 TRP A 491 1 ? 31 
HELX_P HELX_P26 AC8 GLY A 493 ? LEU A 511 ? GLY A 493 LEU A 511 1 ? 19 
HELX_P HELX_P27 AC9 THR A 524 ? ASN A 530 ? THR A 524 ASN A 530 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 50 SG  ? ? ? 1_555 A CYS 121 SG ? ? A CYS 50 A CYS 121 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf2 disulf ?    ? A CYS 62 SG  ? ? ? 1_555 A CYS 102 SG ? ? A CYS 62 A CYS 102 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf3 disulf ?    ? A CYS 88 SG  ? ? ? 1_555 A CYS 142 SG ? ? A CYS 88 A CYS 142 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
covale1 covale one  ? A ASN 71 ND2 ? ? ? 1_555 B NAG .   C1 ? ? A ASN 71 B NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale2 covale both ? B NAG .  O4  ? ? ? 1_555 B NAG .   C1 ? ? B NAG 1  B NAG 2   1_555 ? ? ? ? ? ? ? 1.457 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG B .  ? ASN A 71  ? NAG B 1  ? 1_555 ASN A 71  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 CYS A 50 ? CYS A 121 ? CYS A 50 ? 1_555 CYS A 121 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3 CYS A 62 ? CYS A 102 ? CYS A 62 ? 1_555 CYS A 102 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4 CYS A 88 ? CYS A 142 ? CYS A 88 ? 1_555 CYS A 142 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 48  ? CYS A 50  ? HIS A 48  CYS A 50  
AA1 2 TRP A 125 ? TYR A 127 ? TRP A 125 TYR A 127 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   ARG 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    49 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    ARG 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     49 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   VAL 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    126 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    VAL 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     126 
# 
_pdbx_entry_details.entry_id                   8ET6 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   A 
_pdbx_validate_close_contact.auth_comp_id_1   GLU 
_pdbx_validate_close_contact.auth_seq_id_1    69 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG1 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   THR 
_pdbx_validate_close_contact.auth_seq_id_2    73 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             1.83 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE A 41  ? ? 73.50   -7.40  
2 1 ALA A 83  ? ? -140.14 20.10  
3 1 SER A 101 ? ? 73.92   152.14 
4 1 ALA A 111 ? ? 59.27   16.45  
5 1 VAL A 141 ? ? -102.99 -61.86 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8ET6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   152.3 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'AB INITIO MODEL' 
# 
_em_3d_reconstruction.entry_id                    8ET6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'FOURIER SPACE' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.57 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               102580 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 OCT1 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                8ET6 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4092 
_em_image_scans.dimension_width         5760 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8ET6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           81000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'ZEMLIN TABLEAU' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8ET6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              90 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8ET6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8ET6 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A LYS 534 ? A LYS 534 
3  1 Y 1 A ALA 535 ? A ALA 535 
4  1 Y 1 A LYS 536 ? A LYS 536 
5  1 Y 1 A PRO 537 ? A PRO 537 
6  1 Y 1 A LYS 538 ? A LYS 538 
7  1 Y 1 A GLU 539 ? A GLU 539 
8  1 Y 1 A ASN 540 ? A ASN 540 
9  1 Y 1 A THR 541 ? A THR 541 
10 1 Y 1 A ILE 542 ? A ILE 542 
11 1 Y 1 A TYR 543 ? A TYR 543 
12 1 Y 1 A LEU 544 ? A LEU 544 
13 1 Y 1 A GLN 545 ? A GLN 545 
14 1 Y 1 A VAL 546 ? A VAL 546 
15 1 Y 1 A GLN 547 ? A GLN 547 
16 1 Y 1 A THR 548 ? A THR 548 
17 1 Y 1 A SER 549 ? A SER 549 
18 1 Y 1 A GLU 550 ? A GLU 550 
19 1 Y 1 A LEU 551 ? A LEU 551 
20 1 Y 1 A PRO 552 ? A PRO 552 
21 1 Y 1 A GLY 553 ? A GLY 553 
22 1 Y 1 A THR 554 ? A THR 554 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2022-10-16 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8ET6 
_em_admin.last_update        2024-10-23 
_em_admin.map_release_date   2023-05-31 
_em_admin.title              'Cryo-EM structure of the organic cation transporter 1 in the apo state' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20   mM Tris      1 Tris              
1 150  mM NaCl      2 'Sodium Chloride' 
1 0.06 %  Digitonin 3 Digitonin         
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                60 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               3.7 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     5993 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   5515896 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC 3.2  
'IMAGE ACQUISITION'        ? 2  ? ? 1 Latitude  3.0  
MASKING                    ? 3  ? ? ? ?         ?    
'CTF CORRECTION'           ? 4  1 ? ? ?         ?    
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?    
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?    
'MODEL FITTING'            ? 7  ? 1 ? Coot      0.9  
OTHER                      ? 8  ? ? ? ?         ?    
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    1.19 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC 3.2  
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC 3.2  
CLASSIFICATION             ? 12 1 ? ? cryoSPARC 3.2  
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC 3.2  
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R01GM137421 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
# 
_atom_sites.entry_id                    8ET6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . PRO A 1 2   ? 148.157 102.130 105.985 1.00 88.32  ? 2   PRO A N    1 
ATOM   2    C CA   . PRO A 1 2   ? 147.435 102.172 107.261 1.00 88.32  ? 2   PRO A CA   1 
ATOM   3    C C    . PRO A 1 2   ? 146.188 103.050 107.200 1.00 88.32  ? 2   PRO A C    1 
ATOM   4    O O    . PRO A 1 2   ? 145.979 103.898 108.067 1.00 88.32  ? 2   PRO A O    1 
ATOM   5    C CB   . PRO A 1 2   ? 148.475 102.748 108.227 1.00 88.32  ? 2   PRO A CB   1 
ATOM   6    C CG   . PRO A 1 2   ? 149.363 103.572 107.368 1.00 88.32  ? 2   PRO A CG   1 
ATOM   7    C CD   . PRO A 1 2   ? 149.442 102.847 106.056 1.00 88.32  ? 2   PRO A CD   1 
ATOM   8    H HA   . PRO A 1 2   ? 147.190 101.277 107.544 1.00 88.32  ? 2   PRO A HA   1 
ATOM   9    H HB2  . PRO A 1 2   ? 148.045 103.294 108.904 1.00 88.32  ? 2   PRO A HB2  1 
ATOM   10   H HB3  . PRO A 1 2   ? 148.973 102.024 108.638 1.00 88.32  ? 2   PRO A HB3  1 
ATOM   11   H HG2  . PRO A 1 2   ? 148.975 104.453 107.249 1.00 88.32  ? 2   PRO A HG2  1 
ATOM   12   H HG3  . PRO A 1 2   ? 150.241 103.637 107.776 1.00 88.32  ? 2   PRO A HG3  1 
ATOM   13   H HD2  . PRO A 1 2   ? 149.517 103.479 105.324 1.00 88.32  ? 2   PRO A HD2  1 
ATOM   14   H HD3  . PRO A 1 2   ? 150.180 102.218 106.061 1.00 88.32  ? 2   PRO A HD3  1 
ATOM   15   N N    . THR A 1 3   ? 145.366 102.842 106.178 1.00 83.56  ? 3   THR A N    1 
ATOM   16   C CA   . THR A 1 3   ? 144.125 103.583 106.029 1.00 83.56  ? 3   THR A CA   1 
ATOM   17   C C    . THR A 1 3   ? 143.029 102.947 106.877 1.00 83.56  ? 3   THR A C    1 
ATOM   18   O O    . THR A 1 3   ? 143.125 101.793 107.298 1.00 83.56  ? 3   THR A O    1 
ATOM   19   C CB   . THR A 1 3   ? 143.693 103.634 104.563 1.00 83.56  ? 3   THR A CB   1 
ATOM   20   O OG1  . THR A 1 3   ? 142.581 104.526 104.421 1.00 83.56  ? 3   THR A OG1  1 
ATOM   21   C CG2  . THR A 1 3   ? 143.291 102.252 104.073 1.00 83.56  ? 3   THR A CG2  1 
ATOM   22   H H    . THR A 1 3   ? 145.510 102.271 105.551 1.00 83.56  ? 3   THR A H    1 
ATOM   23   H HA   . THR A 1 3   ? 144.258 104.494 106.337 1.00 83.56  ? 3   THR A HA   1 
ATOM   24   H HB   . THR A 1 3   ? 144.432 103.949 104.019 1.00 83.56  ? 3   THR A HB   1 
ATOM   25   H HG1  . THR A 1 3   ? 142.341 104.560 103.617 1.00 83.56  ? 3   THR A HG1  1 
ATOM   26   H HG21 . THR A 1 3   ? 143.397 102.198 103.110 1.00 83.56  ? 3   THR A HG21 1 
ATOM   27   H HG22 . THR A 1 3   ? 143.845 101.575 104.490 1.00 83.56  ? 3   THR A HG22 1 
ATOM   28   H HG23 . THR A 1 3   ? 142.363 102.082 104.297 1.00 83.56  ? 3   THR A HG23 1 
ATOM   29   N N    . VAL A 1 4   ? 141.973 103.725 107.124 1.00 78.29  ? 4   VAL A N    1 
ATOM   30   C CA   . VAL A 1 4   ? 140.912 103.272 108.020 1.00 78.29  ? 4   VAL A CA   1 
ATOM   31   C C    . VAL A 1 4   ? 140.252 102.010 107.478 1.00 78.29  ? 4   VAL A C    1 
ATOM   32   O O    . VAL A 1 4   ? 139.924 101.090 108.237 1.00 78.29  ? 4   VAL A O    1 
ATOM   33   C CB   . VAL A 1 4   ? 139.883 104.396 108.240 1.00 78.29  ? 4   VAL A CB   1 
ATOM   34   C CG1  . VAL A 1 4   ? 139.144 104.711 106.947 1.00 78.29  ? 4   VAL A CG1  1 
ATOM   35   C CG2  . VAL A 1 4   ? 138.906 104.008 109.338 1.00 78.29  ? 4   VAL A CG2  1 
ATOM   36   H H    . VAL A 1 4   ? 141.850 104.508 106.791 1.00 78.29  ? 4   VAL A H    1 
ATOM   37   H HA   . VAL A 1 4   ? 141.302 103.055 108.881 1.00 78.29  ? 4   VAL A HA   1 
ATOM   38   H HB   . VAL A 1 4   ? 140.348 105.198 108.523 1.00 78.29  ? 4   VAL A HB   1 
ATOM   39   H HG11 . VAL A 1 4   ? 138.667 105.548 107.054 1.00 78.29  ? 4   VAL A HG11 1 
ATOM   40   H HG12 . VAL A 1 4   ? 139.787 104.786 106.225 1.00 78.29  ? 4   VAL A HG12 1 
ATOM   41   H HG13 . VAL A 1 4   ? 138.517 103.996 106.758 1.00 78.29  ? 4   VAL A HG13 1 
ATOM   42   H HG21 . VAL A 1 4   ? 138.315 104.758 109.510 1.00 78.29  ? 4   VAL A HG21 1 
ATOM   43   H HG22 . VAL A 1 4   ? 138.388 103.241 109.048 1.00 78.29  ? 4   VAL A HG22 1 
ATOM   44   H HG23 . VAL A 1 4   ? 139.404 103.788 110.140 1.00 78.29  ? 4   VAL A HG23 1 
ATOM   45   N N    . ASP A 1 5   ? 140.032 101.949 106.164 1.00 79.70  ? 5   ASP A N    1 
ATOM   46   C CA   . ASP A 1 5   ? 139.329 100.807 105.591 1.00 79.70  ? 5   ASP A CA   1 
ATOM   47   C C    . ASP A 1 5   ? 140.149 99.529  105.723 1.00 79.70  ? 5   ASP A C    1 
ATOM   48   O O    . ASP A 1 5   ? 139.623 98.481  106.115 1.00 79.70  ? 5   ASP A O    1 
ATOM   49   C CB   . ASP A 1 5   ? 138.994 101.081 104.125 1.00 79.70  ? 5   ASP A CB   1 
ATOM   50   C CG   . ASP A 1 5   ? 137.955 100.127 103.580 1.00 79.70  ? 5   ASP A CG   1 
ATOM   51   O OD1  . ASP A 1 5   ? 137.470 99.274  104.350 1.00 79.70  ? 5   ASP A OD1  1 
ATOM   52   O OD2  . ASP A 1 5   ? 137.621 100.231 102.381 1.00 79.70  ? 5   ASP A OD2  1 
ATOM   53   H H    . ASP A 1 5   ? 140.276 102.545 105.594 1.00 79.70  ? 5   ASP A H    1 
ATOM   54   H HA   . ASP A 1 5   ? 138.495 100.679 106.070 1.00 79.70  ? 5   ASP A HA   1 
ATOM   55   H HB2  . ASP A 1 5   ? 138.648 101.983 104.042 1.00 79.70  ? 5   ASP A HB2  1 
ATOM   56   H HB3  . ASP A 1 5   ? 139.799 100.983 103.593 1.00 79.70  ? 5   ASP A HB3  1 
ATOM   57   N N    . ASP A 1 6   ? 141.444 99.596  105.403 1.00 84.43  ? 6   ASP A N    1 
ATOM   58   C CA   . ASP A 1 6   ? 142.275 98.396  105.443 1.00 84.43  ? 6   ASP A CA   1 
ATOM   59   C C    . ASP A 1 6   ? 142.384 97.840  106.857 1.00 84.43  ? 6   ASP A C    1 
ATOM   60   O O    . ASP A 1 6   ? 142.244 96.630  107.067 1.00 84.43  ? 6   ASP A O    1 
ATOM   61   C CB   . ASP A 1 6   ? 143.662 98.701  104.880 1.00 84.43  ? 6   ASP A CB   1 
ATOM   62   C CG   . ASP A 1 6   ? 143.632 99.024  103.401 1.00 84.43  ? 6   ASP A CG   1 
ATOM   63   O OD1  . ASP A 1 6   ? 142.547 98.918  102.791 1.00 84.43  ? 6   ASP A OD1  1 
ATOM   64   O OD2  . ASP A 1 6   ? 144.692 99.384  102.847 1.00 84.43  ? 6   ASP A OD2  1 
ATOM   65   H H    . ASP A 1 6   ? 141.857 100.310 105.166 1.00 84.43  ? 6   ASP A H    1 
ATOM   66   H HA   . ASP A 1 6   ? 141.870 97.714  104.885 1.00 84.43  ? 6   ASP A HA   1 
ATOM   67   H HB2  . ASP A 1 6   ? 144.033 99.464  105.349 1.00 84.43  ? 6   ASP A HB2  1 
ATOM   68   H HB3  . ASP A 1 6   ? 144.231 97.925  105.006 1.00 84.43  ? 6   ASP A HB3  1 
ATOM   69   N N    . VAL A 1 7   ? 142.632 98.706  107.842 1.00 81.92  ? 7   VAL A N    1 
ATOM   70   C CA   . VAL A 1 7   ? 142.723 98.233  109.220 1.00 81.92  ? 7   VAL A CA   1 
ATOM   71   C C    . VAL A 1 7   ? 141.395 97.631  109.655 1.00 81.92  ? 7   VAL A C    1 
ATOM   72   O O    . VAL A 1 7   ? 141.357 96.639  110.392 1.00 81.92  ? 7   VAL A O    1 
ATOM   73   C CB   . VAL A 1 7   ? 143.166 99.372  110.157 1.00 81.92  ? 7   VAL A CB   1 
ATOM   74   C CG1  . VAL A 1 7   ? 144.535 99.892  109.748 1.00 81.92  ? 7   VAL A CG1  1 
ATOM   75   C CG2  . VAL A 1 7   ? 142.146 100.497 110.166 1.00 81.92  ? 7   VAL A CG2  1 
ATOM   76   H H    . VAL A 1 7   ? 142.748 99.551  107.740 1.00 81.92  ? 7   VAL A H    1 
ATOM   77   H HA   . VAL A 1 7   ? 143.393 97.534  109.267 1.00 81.92  ? 7   VAL A HA   1 
ATOM   78   H HB   . VAL A 1 7   ? 143.237 99.027  111.061 1.00 81.92  ? 7   VAL A HB   1 
ATOM   79   H HG11 . VAL A 1 7   ? 144.801 100.594 110.362 1.00 81.92  ? 7   VAL A HG11 1 
ATOM   80   H HG12 . VAL A 1 7   ? 145.173 99.162  109.783 1.00 81.92  ? 7   VAL A HG12 1 
ATOM   81   H HG13 . VAL A 1 7   ? 144.484 100.244 108.845 1.00 81.92  ? 7   VAL A HG13 1 
ATOM   82   H HG21 . VAL A 1 7   ? 142.472 101.209 110.739 1.00 81.92  ? 7   VAL A HG21 1 
ATOM   83   H HG22 . VAL A 1 7   ? 142.036 100.828 109.263 1.00 81.92  ? 7   VAL A HG22 1 
ATOM   84   H HG23 . VAL A 1 7   ? 141.301 100.166 110.507 1.00 81.92  ? 7   VAL A HG23 1 
ATOM   85   N N    . LEU A 1 8   ? 140.285 98.218  109.202 1.00 75.82  ? 8   LEU A N    1 
ATOM   86   C CA   . LEU A 1 8   ? 138.976 97.657  109.520 1.00 75.82  ? 8   LEU A CA   1 
ATOM   87   C C    . LEU A 1 8   ? 138.824 96.262  108.929 1.00 75.82  ? 8   LEU A C    1 
ATOM   88   O O    . LEU A 1 8   ? 138.233 95.375  109.555 1.00 75.82  ? 8   LEU A O    1 
ATOM   89   C CB   . LEU A 1 8   ? 137.873 98.583  109.010 1.00 75.82  ? 8   LEU A CB   1 
ATOM   90   C CG   . LEU A 1 8   ? 136.437 98.161  109.328 1.00 75.82  ? 8   LEU A CG   1 
ATOM   91   C CD1  . LEU A 1 8   ? 136.238 97.987  110.825 1.00 75.82  ? 8   LEU A CD1  1 
ATOM   92   C CD2  . LEU A 1 8   ? 135.454 99.177  108.774 1.00 75.82  ? 8   LEU A CD2  1 
ATOM   93   H H    . LEU A 1 8   ? 140.263 98.928  108.718 1.00 75.82  ? 8   LEU A H    1 
ATOM   94   H HA   . LEU A 1 8   ? 138.892 97.586  110.483 1.00 75.82  ? 8   LEU A HA   1 
ATOM   95   H HB2  . LEU A 1 8   ? 138.008 99.462  109.399 1.00 75.82  ? 8   LEU A HB2  1 
ATOM   96   H HB3  . LEU A 1 8   ? 137.948 98.644  108.045 1.00 75.82  ? 8   LEU A HB3  1 
ATOM   97   H HG   . LEU A 1 8   ? 136.257 97.309  108.902 1.00 75.82  ? 8   LEU A HG   1 
ATOM   98   H HD11 . LEU A 1 8   ? 135.294 97.858  111.003 1.00 75.82  ? 8   LEU A HD11 1 
ATOM   99   H HD12 . LEU A 1 8   ? 136.739 97.212  111.124 1.00 75.82  ? 8   LEU A HD12 1 
ATOM   100  H HD13 . LEU A 1 8   ? 136.554 98.784  111.280 1.00 75.82  ? 8   LEU A HD13 1 
ATOM   101  H HD21 . LEU A 1 8   ? 134.551 98.859  108.932 1.00 75.82  ? 8   LEU A HD21 1 
ATOM   102  H HD22 . LEU A 1 8   ? 135.589 100.025 109.223 1.00 75.82  ? 8   LEU A HD22 1 
ATOM   103  H HD23 . LEU A 1 8   ? 135.607 99.277  107.821 1.00 75.82  ? 8   LEU A HD23 1 
ATOM   104  N N    . GLU A 1 9   ? 139.346 96.050  107.720 1.00 79.92  ? 9   GLU A N    1 
ATOM   105  C CA   . GLU A 1 9   ? 139.317 94.718  107.127 1.00 79.92  ? 9   GLU A CA   1 
ATOM   106  C C    . GLU A 1 9   ? 140.112 93.732  107.973 1.00 79.92  ? 9   GLU A C    1 
ATOM   107  O O    . GLU A 1 9   ? 139.666 92.607  108.224 1.00 79.92  ? 9   GLU A O    1 
ATOM   108  C CB   . GLU A 1 9   ? 139.864 94.774  105.699 1.00 79.92  ? 9   GLU A CB   1 
ATOM   109  C CG   . GLU A 1 9   ? 139.971 93.422  104.999 1.00 79.92  ? 9   GLU A CG   1 
ATOM   110  C CD   . GLU A 1 9   ? 141.256 92.679  105.324 1.00 79.92  ? 9   GLU A CD   1 
ATOM   111  O OE1  . GLU A 1 9   ? 142.118 93.245  106.028 1.00 79.92  ? 9   GLU A OE1  1 
ATOM   112  O OE2  . GLU A 1 9   ? 141.403 91.524  104.873 1.00 79.92  ? 9   GLU A OE2  1 
ATOM   113  H H    . GLU A 1 9   ? 139.717 96.652  107.231 1.00 79.92  ? 9   GLU A H    1 
ATOM   114  H HA   . GLU A 1 9   ? 138.398 94.408  107.086 1.00 79.92  ? 9   GLU A HA   1 
ATOM   115  H HB2  . GLU A 1 9   ? 139.276 95.331  105.167 1.00 79.92  ? 9   GLU A HB2  1 
ATOM   116  H HB3  . GLU A 1 9   ? 140.749 95.168  105.722 1.00 79.92  ? 9   GLU A HB3  1 
ATOM   117  H HG2  . GLU A 1 9   ? 139.225 92.865  105.271 1.00 79.92  ? 9   GLU A HG2  1 
ATOM   118  H HG3  . GLU A 1 9   ? 139.945 93.564  104.040 1.00 79.92  ? 9   GLU A HG3  1 
ATOM   119  N N    . GLN A 1 10  ? 141.298 94.143  108.425 1.00 84.49  ? 10  GLN A N    1 
ATOM   120  C CA   . GLN A 1 10  ? 142.151 93.238  109.187 1.00 84.49  ? 10  GLN A CA   1 
ATOM   121  C C    . GLN A 1 10  ? 141.502 92.849  110.510 1.00 84.49  ? 10  GLN A C    1 
ATOM   122  O O    . GLN A 1 10  ? 141.602 91.695  110.943 1.00 84.49  ? 10  GLN A O    1 
ATOM   123  C CB   . GLN A 1 10  ? 143.516 93.888  109.418 1.00 84.49  ? 10  GLN A CB   1 
ATOM   124  C CG   . GLN A 1 10  ? 144.557 92.970  110.041 1.00 84.49  ? 10  GLN A CG   1 
ATOM   125  C CD   . GLN A 1 10  ? 144.583 93.047  111.554 1.00 84.49  ? 10  GLN A CD   1 
ATOM   126  O OE1  . GLN A 1 10  ? 143.716 93.662  112.174 1.00 84.49  ? 10  GLN A OE1  1 
ATOM   127  N NE2  . GLN A 1 10  ? 145.589 92.425  112.158 1.00 84.49  ? 10  GLN A NE2  1 
ATOM   128  H H    . GLN A 1 10  ? 141.624 94.930  108.307 1.00 84.49  ? 10  GLN A H    1 
ATOM   129  H HA   . GLN A 1 10  ? 142.289 92.427  108.673 1.00 84.49  ? 10  GLN A HA   1 
ATOM   130  H HB2  . GLN A 1 10  ? 143.864 94.185  108.562 1.00 84.49  ? 10  GLN A HB2  1 
ATOM   131  H HB3  . GLN A 1 10  ? 143.403 94.651  110.004 1.00 84.49  ? 10  GLN A HB3  1 
ATOM   132  H HG2  . GLN A 1 10  ? 144.360 92.053  109.791 1.00 84.49  ? 10  GLN A HG2  1 
ATOM   133  H HG3  . GLN A 1 10  ? 145.435 93.221  109.714 1.00 84.49  ? 10  GLN A HG3  1 
ATOM   134  H HE21 . GLN A 1 10  ? 146.178 92.006  111.692 1.00 84.49  ? 10  GLN A HE21 1 
ATOM   135  H HE22 . GLN A 1 10  ? 145.650 92.439  113.016 1.00 84.49  ? 10  GLN A HE22 1 
ATOM   136  N N    . VAL A 1 11  ? 140.830 93.800  111.169 1.00 80.70  ? 11  VAL A N    1 
ATOM   137  C CA   . VAL A 1 11  ? 140.196 93.532  112.457 1.00 80.70  ? 11  VAL A CA   1 
ATOM   138  C C    . VAL A 1 11  ? 138.773 93.008  112.318 1.00 80.70  ? 11  VAL A C    1 
ATOM   139  O O    . VAL A 1 11  ? 138.074 92.869  113.331 1.00 80.70  ? 11  VAL A O    1 
ATOM   140  C CB   . VAL A 1 11  ? 140.198 94.798  113.341 1.00 80.70  ? 11  VAL A CB   1 
ATOM   141  C CG1  . VAL A 1 11  ? 141.623 95.214  113.661 1.00 80.70  ? 11  VAL A CG1  1 
ATOM   142  C CG2  . VAL A 1 11  ? 139.450 95.933  112.659 1.00 80.70  ? 11  VAL A CG2  1 
ATOM   143  H H    . VAL A 1 11  ? 140.733 94.608  110.890 1.00 80.70  ? 11  VAL A H    1 
ATOM   144  H HA   . VAL A 1 11  ? 140.714 92.855  112.919 1.00 80.70  ? 11  VAL A HA   1 
ATOM   145  H HB   . VAL A 1 11  ? 139.747 94.601  114.177 1.00 80.70  ? 11  VAL A HB   1 
ATOM   146  H HG11 . VAL A 1 11  ? 141.602 95.985  114.249 1.00 80.70  ? 11  VAL A HG11 1 
ATOM   147  H HG12 . VAL A 1 11  ? 142.077 94.476  114.097 1.00 80.70  ? 11  VAL A HG12 1 
ATOM   148  H HG13 . VAL A 1 11  ? 142.077 95.441  112.835 1.00 80.70  ? 11  VAL A HG13 1 
ATOM   149  H HG21 . VAL A 1 11  ? 138.764 96.262  113.261 1.00 80.70  ? 11  VAL A HG21 1 
ATOM   150  H HG22 . VAL A 1 11  ? 140.078 96.645  112.457 1.00 80.70  ? 11  VAL A HG22 1 
ATOM   151  H HG23 . VAL A 1 11  ? 139.044 95.608  111.843 1.00 80.70  ? 11  VAL A HG23 1 
ATOM   152  N N    . GLY A 1 12  ? 138.318 92.720  111.101 1.00 76.58  ? 12  GLY A N    1 
ATOM   153  C CA   . GLY A 1 12  ? 136.997 92.156  110.897 1.00 76.58  ? 12  GLY A CA   1 
ATOM   154  C C    . GLY A 1 12  ? 135.972 93.184  110.468 1.00 76.58  ? 12  GLY A C    1 
ATOM   155  O O    . GLY A 1 12  ? 135.626 94.084  111.239 1.00 76.58  ? 12  GLY A O    1 
ATOM   156  H H    . GLY A 1 12  ? 138.761 92.846  110.374 1.00 76.58  ? 12  GLY A H    1 
ATOM   157  H HA2  . GLY A 1 12  ? 137.044 91.470  110.213 1.00 76.58  ? 12  GLY A HA2  1 
ATOM   158  H HA3  . GLY A 1 12  ? 136.688 91.746  111.720 1.00 76.58  ? 12  GLY A HA3  1 
ATOM   159  N N    . GLU A 1 13  ? 135.474 93.061  109.236 1.00 68.48  ? 13  GLU A N    1 
ATOM   160  C CA   . GLU A 1 13  ? 134.516 94.037  108.726 1.00 68.48  ? 13  GLU A CA   1 
ATOM   161  C C    . GLU A 1 13  ? 133.198 93.969  109.489 1.00 68.48  ? 13  GLU A C    1 
ATOM   162  O O    . GLU A 1 13  ? 132.642 95.002  109.877 1.00 68.48  ? 13  GLU A O    1 
ATOM   163  C CB   . GLU A 1 13  ? 134.295 93.818  107.230 1.00 68.48  ? 13  GLU A CB   1 
ATOM   164  C CG   . GLU A 1 13  ? 135.542 94.084  106.395 1.00 68.48  ? 13  GLU A CG   1 
ATOM   165  C CD   . GLU A 1 13  ? 135.301 93.963  104.901 1.00 68.48  ? 13  GLU A CD   1 
ATOM   166  O OE1  . GLU A 1 13  ? 134.145 93.716  104.498 1.00 68.48  ? 13  GLU A OE1  1 
ATOM   167  O OE2  . GLU A 1 13  ? 136.270 94.118  104.128 1.00 68.48  ? 13  GLU A OE2  1 
ATOM   168  H H    . GLU A 1 13  ? 135.670 92.430  108.686 1.00 68.48  ? 13  GLU A H    1 
ATOM   169  H HA   . GLU A 1 13  ? 134.883 94.927  108.846 1.00 68.48  ? 13  GLU A HA   1 
ATOM   170  H HB2  . GLU A 1 13  ? 134.025 92.898  107.081 1.00 68.48  ? 13  GLU A HB2  1 
ATOM   171  H HB3  . GLU A 1 13  ? 133.598 94.420  106.924 1.00 68.48  ? 13  GLU A HB3  1 
ATOM   172  H HG2  . GLU A 1 13  ? 135.853 94.985  106.575 1.00 68.48  ? 13  GLU A HG2  1 
ATOM   173  H HG3  . GLU A 1 13  ? 136.227 93.443  106.641 1.00 68.48  ? 13  GLU A HG3  1 
ATOM   174  N N    . PHE A 1 14  ? 132.680 92.762  109.713 1.00 63.32  ? 14  PHE A N    1 
ATOM   175  C CA   . PHE A 1 14  ? 131.426 92.556  110.441 1.00 63.32  ? 14  PHE A CA   1 
ATOM   176  C C    . PHE A 1 14  ? 131.673 91.467  111.482 1.00 63.32  ? 14  PHE A C    1 
ATOM   177  O O    . PHE A 1 14  ? 131.346 90.298  111.262 1.00 63.32  ? 14  PHE A O    1 
ATOM   178  C CB   . PHE A 1 14  ? 130.302 92.184  109.476 1.00 63.32  ? 14  PHE A CB   1 
ATOM   179  C CG   . PHE A 1 14  ? 128.929 92.238  110.083 1.00 63.32  ? 14  PHE A CG   1 
ATOM   180  C CD1  . PHE A 1 14  ? 128.272 93.447  110.238 1.00 63.32  ? 14  PHE A CD1  1 
ATOM   181  C CD2  . PHE A 1 14  ? 128.284 91.077  110.476 1.00 63.32  ? 14  PHE A CD2  1 
ATOM   182  C CE1  . PHE A 1 14  ? 127.005 93.499  110.787 1.00 63.32  ? 14  PHE A CE1  1 
ATOM   183  C CE2  . PHE A 1 14  ? 127.016 91.123  111.025 1.00 63.32  ? 14  PHE A CE2  1 
ATOM   184  C CZ   . PHE A 1 14  ? 126.377 92.335  111.181 1.00 63.32  ? 14  PHE A CZ   1 
ATOM   185  H H    . PHE A 1 14  ? 133.045 92.029  109.448 1.00 63.32  ? 14  PHE A H    1 
ATOM   186  H HA   . PHE A 1 14  ? 131.177 93.371  110.903 1.00 63.32  ? 14  PHE A HA   1 
ATOM   187  H HB2  . PHE A 1 14  ? 130.318 92.799  108.726 1.00 63.32  ? 14  PHE A HB2  1 
ATOM   188  H HB3  . PHE A 1 14  ? 130.450 91.278  109.161 1.00 63.32  ? 14  PHE A HB3  1 
ATOM   189  H HD1  . PHE A 1 14  ? 128.692 94.234  109.976 1.00 63.32  ? 14  PHE A HD1  1 
ATOM   190  H HD2  . PHE A 1 14  ? 128.710 90.257  110.374 1.00 63.32  ? 14  PHE A HD2  1 
ATOM   191  H HE1  . PHE A 1 14  ? 126.576 94.317  110.891 1.00 63.32  ? 14  PHE A HE1  1 
ATOM   192  H HE2  . PHE A 1 14  ? 126.595 90.337  111.290 1.00 63.32  ? 14  PHE A HE2  1 
ATOM   193  H HZ   . PHE A 1 14  ? 125.524 92.368  111.551 1.00 63.32  ? 14  PHE A HZ   1 
ATOM   194  N N    . GLY A 1 15  ? 132.242 91.855  112.617 1.00 69.96  ? 15  GLY A N    1 
ATOM   195  C CA   . GLY A 1 15  ? 132.533 90.937  113.698 1.00 69.96  ? 15  GLY A CA   1 
ATOM   196  C C    . GLY A 1 15  ? 131.442 90.932  114.746 1.00 69.96  ? 15  GLY A C    1 
ATOM   197  O O    . GLY A 1 15  ? 130.331 91.422  114.530 1.00 69.96  ? 15  GLY A O    1 
ATOM   198  H H    . GLY A 1 15  ? 132.473 92.667  112.785 1.00 69.96  ? 15  GLY A H    1 
ATOM   199  H HA2  . GLY A 1 15  ? 132.625 90.038  113.345 1.00 69.96  ? 15  GLY A HA2  1 
ATOM   200  H HA3  . GLY A 1 15  ? 133.368 91.188  114.123 1.00 69.96  ? 15  GLY A HA3  1 
ATOM   201  N N    . TRP A 1 16  ? 131.770 90.366  115.909 1.00 70.71  ? 16  TRP A N    1 
ATOM   202  C CA   . TRP A 1 16  ? 130.801 90.352  116.999 1.00 70.71  ? 16  TRP A CA   1 
ATOM   203  C C    . TRP A 1 16  ? 130.557 91.754  117.537 1.00 70.71  ? 16  TRP A C    1 
ATOM   204  O O    . TRP A 1 16  ? 129.476 92.031  118.066 1.00 70.71  ? 16  TRP A O    1 
ATOM   205  C CB   . TRP A 1 16  ? 131.270 89.429  118.123 1.00 70.71  ? 16  TRP A CB   1 
ATOM   206  C CG   . TRP A 1 16  ? 130.180 89.097  119.095 1.00 70.71  ? 16  TRP A CG   1 
ATOM   207  C CD1  . TRP A 1 16  ? 129.320 88.040  119.031 1.00 70.71  ? 16  TRP A CD1  1 
ATOM   208  C CD2  . TRP A 1 16  ? 129.825 89.831  120.273 1.00 70.71  ? 16  TRP A CD2  1 
ATOM   209  N NE1  . TRP A 1 16  ? 128.454 88.068  120.097 1.00 70.71  ? 16  TRP A NE1  1 
ATOM   210  C CE2  . TRP A 1 16  ? 128.744 89.158  120.875 1.00 70.71  ? 16  TRP A CE2  1 
ATOM   211  C CE3  . TRP A 1 16  ? 130.319 90.990  120.879 1.00 70.71  ? 16  TRP A CE3  1 
ATOM   212  C CZ2  . TRP A 1 16  ? 128.147 89.605  122.051 1.00 70.71  ? 16  TRP A CZ2  1 
ATOM   213  C CZ3  . TRP A 1 16  ? 129.725 91.432  122.047 1.00 70.71  ? 16  TRP A CZ3  1 
ATOM   214  C CH2  . TRP A 1 16  ? 128.651 90.741  122.621 1.00 70.71  ? 16  TRP A CH2  1 
ATOM   215  H H    . TRP A 1 16  ? 132.524 89.993  116.088 1.00 70.71  ? 16  TRP A H    1 
ATOM   216  H HA   . TRP A 1 16  ? 129.957 90.010  116.665 1.00 70.71  ? 16  TRP A HA   1 
ATOM   217  H HB2  . TRP A 1 16  ? 131.589 88.599  117.738 1.00 70.71  ? 16  TRP A HB2  1 
ATOM   218  H HB3  . TRP A 1 16  ? 131.985 89.864  118.613 1.00 70.71  ? 16  TRP A HB3  1 
ATOM   219  H HD1  . TRP A 1 16  ? 129.319 87.394  118.362 1.00 70.71  ? 16  TRP A HD1  1 
ATOM   220  H HE1  . TRP A 1 16  ? 127.831 87.495  120.251 1.00 70.71  ? 16  TRP A HE1  1 
ATOM   221  H HE3  . TRP A 1 16  ? 131.032 91.455  120.504 1.00 70.71  ? 16  TRP A HE3  1 
ATOM   222  H HZ2  . TRP A 1 16  ? 127.434 89.148  122.436 1.00 70.71  ? 16  TRP A HZ2  1 
ATOM   223  H HZ3  . TRP A 1 16  ? 130.045 92.202  122.459 1.00 70.71  ? 16  TRP A HZ3  1 
ATOM   224  H HH2  . TRP A 1 16  ? 128.272 91.062  123.407 1.00 70.71  ? 16  TRP A HH2  1 
ATOM   225  N N    . PHE A 1 17  ? 131.542 92.646  117.417 1.00 68.38  ? 17  PHE A N    1 
ATOM   226  C CA   . PHE A 1 17  ? 131.319 94.032  117.812 1.00 68.38  ? 17  PHE A CA   1 
ATOM   227  C C    . PHE A 1 17  ? 130.263 94.688  116.934 1.00 68.38  ? 17  PHE A C    1 
ATOM   228  O O    . PHE A 1 17  ? 129.362 95.376  117.436 1.00 68.38  ? 17  PHE A O    1 
ATOM   229  C CB   . PHE A 1 17  ? 132.624 94.821  117.741 1.00 68.38  ? 17  PHE A CB   1 
ATOM   230  C CG   . PHE A 1 17  ? 132.427 96.305  117.810 1.00 68.38  ? 17  PHE A CG   1 
ATOM   231  C CD1  . PHE A 1 17  ? 132.241 96.933  119.026 1.00 68.38  ? 17  PHE A CD1  1 
ATOM   232  C CD2  . PHE A 1 17  ? 132.415 97.069  116.658 1.00 68.38  ? 17  PHE A CD2  1 
ATOM   233  C CE1  . PHE A 1 17  ? 132.054 98.295  119.093 1.00 68.38  ? 17  PHE A CE1  1 
ATOM   234  C CE2  . PHE A 1 17  ? 132.229 98.432  116.719 1.00 68.38  ? 17  PHE A CE2  1 
ATOM   235  C CZ   . PHE A 1 17  ? 132.048 99.046  117.937 1.00 68.38  ? 17  PHE A CZ   1 
ATOM   236  H H    . PHE A 1 17  ? 132.331 92.477  117.118 1.00 68.38  ? 17  PHE A H    1 
ATOM   237  H HA   . PHE A 1 17  ? 131.005 94.054  118.729 1.00 68.38  ? 17  PHE A HA   1 
ATOM   238  H HB2  . PHE A 1 17  ? 133.191 94.560  118.483 1.00 68.38  ? 17  PHE A HB2  1 
ATOM   239  H HB3  . PHE A 1 17  ? 133.067 94.619  116.902 1.00 68.38  ? 17  PHE A HB3  1 
ATOM   240  H HD1  . PHE A 1 17  ? 132.245 96.430  119.809 1.00 68.38  ? 17  PHE A HD1  1 
ATOM   241  H HD2  . PHE A 1 17  ? 132.537 96.658  115.832 1.00 68.38  ? 17  PHE A HD2  1 
ATOM   242  H HE1  . PHE A 1 17  ? 131.933 98.709  119.917 1.00 68.38  ? 17  PHE A HE1  1 
ATOM   243  H HE2  . PHE A 1 17  ? 132.224 98.936  115.938 1.00 68.38  ? 17  PHE A HE2  1 
ATOM   244  H HZ   . PHE A 1 17  ? 131.922 99.966  117.981 1.00 68.38  ? 17  PHE A HZ   1 
ATOM   245  N N    . GLN A 1 18  ? 130.352 94.484  115.618 1.00 65.49  ? 18  GLN A N    1 
ATOM   246  C CA   . GLN A 1 18  ? 129.376 95.088  114.721 1.00 65.49  ? 18  GLN A CA   1 
ATOM   247  C C    . GLN A 1 18  ? 127.972 94.598  115.039 1.00 65.49  ? 18  GLN A C    1 
ATOM   248  O O    . GLN A 1 18  ? 127.016 95.377  115.011 1.00 65.49  ? 18  GLN A O    1 
ATOM   249  C CB   . GLN A 1 18  ? 129.733 94.788  113.265 1.00 65.49  ? 18  GLN A CB   1 
ATOM   250  C CG   . GLN A 1 18  ? 130.793 95.708  112.687 1.00 65.49  ? 18  GLN A CG   1 
ATOM   251  C CD   . GLN A 1 18  ? 132.147 95.510  113.329 1.00 65.49  ? 18  GLN A CD   1 
ATOM   252  O OE1  . GLN A 1 18  ? 132.293 94.725  114.264 1.00 65.49  ? 18  GLN A OE1  1 
ATOM   253  N NE2  . GLN A 1 18  ? 133.149 96.223  112.827 1.00 65.49  ? 18  GLN A NE2  1 
ATOM   254  H H    . GLN A 1 18  ? 130.954 94.008  115.230 1.00 65.49  ? 18  GLN A H    1 
ATOM   255  H HA   . GLN A 1 18  ? 129.391 96.051  114.840 1.00 65.49  ? 18  GLN A HA   1 
ATOM   256  H HB2  . GLN A 1 18  ? 130.068 93.879  113.206 1.00 65.49  ? 18  GLN A HB2  1 
ATOM   257  H HB3  . GLN A 1 18  ? 128.935 94.878  112.721 1.00 65.49  ? 18  GLN A HB3  1 
ATOM   258  H HG2  . GLN A 1 18  ? 130.881 95.536  111.736 1.00 65.49  ? 18  GLN A HG2  1 
ATOM   259  H HG3  . GLN A 1 18  ? 130.524 96.628  112.834 1.00 65.49  ? 18  GLN A HG3  1 
ATOM   260  H HE21 . GLN A 1 18  ? 133.007 96.762  112.172 1.00 65.49  ? 18  GLN A HE21 1 
ATOM   261  H HE22 . GLN A 1 18  ? 133.939 96.147  113.158 1.00 65.49  ? 18  GLN A HE22 1 
ATOM   262  N N    . LYS A 1 19  ? 127.828 93.308  115.346 1.00 63.30  ? 19  LYS A N    1 
ATOM   263  C CA   . LYS A 1 19  ? 126.506 92.773  115.652 1.00 63.30  ? 19  LYS A CA   1 
ATOM   264  C C    . LYS A 1 19  ? 125.917 93.427  116.897 1.00 63.30  ? 19  LYS A C    1 
ATOM   265  O O    . LYS A 1 19  ? 124.744 93.813  116.905 1.00 63.30  ? 19  LYS A O    1 
ATOM   266  C CB   . LYS A 1 19  ? 126.587 91.257  115.821 1.00 63.30  ? 19  LYS A CB   1 
ATOM   267  C CG   . LYS A 1 19  ? 127.019 90.530  114.560 1.00 63.30  ? 19  LYS A CG   1 
ATOM   268  C CD   . LYS A 1 19  ? 127.134 89.035  114.787 1.00 63.30  ? 19  LYS A CD   1 
ATOM   269  C CE   . LYS A 1 19  ? 127.557 88.313  113.520 1.00 63.30  ? 19  LYS A CE   1 
ATOM   270  N NZ   . LYS A 1 19  ? 127.674 86.847  113.741 1.00 63.30  ? 19  LYS A NZ   1 
ATOM   271  H H    . LYS A 1 19  ? 128.467 92.734  115.385 1.00 63.30  ? 19  LYS A H    1 
ATOM   272  H HA   . LYS A 1 19  ? 125.912 92.958  114.908 1.00 63.30  ? 19  LYS A HA   1 
ATOM   273  H HB2  . LYS A 1 19  ? 127.229 91.051  116.519 1.00 63.30  ? 19  LYS A HB2  1 
ATOM   274  H HB3  . LYS A 1 19  ? 125.711 90.922  116.071 1.00 63.30  ? 19  LYS A HB3  1 
ATOM   275  H HG2  . LYS A 1 19  ? 126.361 90.681  113.863 1.00 63.30  ? 19  LYS A HG2  1 
ATOM   276  H HG3  . LYS A 1 19  ? 127.886 90.862  114.279 1.00 63.30  ? 19  LYS A HG3  1 
ATOM   277  H HD2  . LYS A 1 19  ? 127.801 88.863  115.470 1.00 63.30  ? 19  LYS A HD2  1 
ATOM   278  H HD3  . LYS A 1 19  ? 126.272 88.685  115.062 1.00 63.30  ? 19  LYS A HD3  1 
ATOM   279  H HE2  . LYS A 1 19  ? 126.893 88.465  112.829 1.00 63.30  ? 19  LYS A HE2  1 
ATOM   280  H HE3  . LYS A 1 19  ? 128.421 88.648  113.234 1.00 63.30  ? 19  LYS A HE3  1 
ATOM   281  H HZ1  . LYS A 1 19  ? 127.920 86.445  112.986 1.00 63.30  ? 19  LYS A HZ1  1 
ATOM   282  H HZ2  . LYS A 1 19  ? 128.283 86.683  114.368 1.00 63.30  ? 19  LYS A HZ2  1 
ATOM   283  H HZ3  . LYS A 1 19  ? 126.891 86.517  114.004 1.00 63.30  ? 19  LYS A HZ3  1 
ATOM   284  N N    . GLN A 1 20  ? 126.713 93.564  117.960 1.00 64.31  ? 20  GLN A N    1 
ATOM   285  C CA   . GLN A 1 20  ? 126.207 94.188  119.179 1.00 64.31  ? 20  GLN A CA   1 
ATOM   286  C C    . GLN A 1 20  ? 125.838 95.648  118.937 1.00 64.31  ? 20  GLN A C    1 
ATOM   287  O O    . GLN A 1 20  ? 124.771 96.117  119.369 1.00 64.31  ? 20  GLN A O    1 
ATOM   288  C CB   . GLN A 1 20  ? 127.250 94.074  120.292 1.00 64.31  ? 20  GLN A CB   1 
ATOM   289  C CG   . GLN A 1 20  ? 126.756 94.507  121.666 1.00 64.31  ? 20  GLN A CG   1 
ATOM   290  C CD   . GLN A 1 20  ? 127.886 94.737  122.655 1.00 64.31  ? 20  GLN A CD   1 
ATOM   291  O OE1  . GLN A 1 20  ? 128.969 95.191  122.283 1.00 64.31  ? 20  GLN A OE1  1 
ATOM   292  N NE2  . GLN A 1 20  ? 127.638 94.424  123.922 1.00 64.31  ? 20  GLN A NE2  1 
ATOM   293  H H    . GLN A 1 20  ? 127.535 93.311  117.998 1.00 64.31  ? 20  GLN A H    1 
ATOM   294  H HA   . GLN A 1 20  ? 125.408 93.719  119.466 1.00 64.31  ? 20  GLN A HA   1 
ATOM   295  H HB2  . GLN A 1 20  ? 127.526 93.146  120.360 1.00 64.31  ? 20  GLN A HB2  1 
ATOM   296  H HB3  . GLN A 1 20  ? 128.015 94.625  120.063 1.00 64.31  ? 20  GLN A HB3  1 
ATOM   297  H HG2  . GLN A 1 20  ? 126.258 95.334  121.582 1.00 64.31  ? 20  GLN A HG2  1 
ATOM   298  H HG3  . GLN A 1 20  ? 126.185 93.810  122.027 1.00 64.31  ? 20  GLN A HG3  1 
ATOM   299  H HE21 . GLN A 1 20  ? 126.870 94.109  124.145 1.00 64.31  ? 20  GLN A HE21 1 
ATOM   300  H HE22 . GLN A 1 20  ? 128.247 94.537  124.519 1.00 64.31  ? 20  GLN A HE22 1 
ATOM   301  N N    . ALA A 1 21  ? 126.706 96.384  118.238 1.00 59.00  ? 21  ALA A N    1 
ATOM   302  C CA   . ALA A 1 21  ? 126.415 97.786  117.968 1.00 59.00  ? 21  ALA A CA   1 
ATOM   303  C C    . ALA A 1 21  ? 125.149 97.926  117.135 1.00 59.00  ? 21  ALA A C    1 
ATOM   304  O O    . ALA A 1 21  ? 124.308 98.793  117.407 1.00 59.00  ? 21  ALA A O    1 
ATOM   305  C CB   . ALA A 1 21  ? 127.602 98.440  117.263 1.00 59.00  ? 21  ALA A CB   1 
ATOM   306  H H    . ALA A 1 21  ? 127.452 96.100  117.917 1.00 59.00  ? 21  ALA A H    1 
ATOM   307  H HA   . ALA A 1 21  ? 126.276 98.246  118.810 1.00 59.00  ? 21  ALA A HA   1 
ATOM   308  H HB1  . ALA A 1 21  ? 127.397 99.372  117.090 1.00 59.00  ? 21  ALA A HB1  1 
ATOM   309  H HB2  . ALA A 1 21  ? 128.381 98.374  117.837 1.00 59.00  ? 21  ALA A HB2  1 
ATOM   310  H HB3  . ALA A 1 21  ? 127.769 97.976  116.427 1.00 59.00  ? 21  ALA A HB3  1 
ATOM   311  N N    . PHE A 1 22  ? 124.987 97.072  116.122 1.00 53.45  ? 22  PHE A N    1 
ATOM   312  C CA   . PHE A 1 22  ? 123.781 97.124  115.309 1.00 53.45  ? 22  PHE A CA   1 
ATOM   313  C C    . PHE A 1 22  ? 122.549 96.772  116.124 1.00 53.45  ? 22  PHE A C    1 
ATOM   314  O O    . PHE A 1 22  ? 121.479 97.341  115.903 1.00 53.45  ? 22  PHE A O    1 
ATOM   315  C CB   . PHE A 1 22  ? 123.880 96.183  114.116 1.00 53.45  ? 22  PHE A CB   1 
ATOM   316  C CG   . PHE A 1 22  ? 122.619 96.128  113.314 1.00 53.45  ? 22  PHE A CG   1 
ATOM   317  C CD1  . PHE A 1 22  ? 122.335 97.114  112.391 1.00 53.45  ? 22  PHE A CD1  1 
ATOM   318  C CD2  . PHE A 1 22  ? 121.699 95.116  113.512 1.00 53.45  ? 22  PHE A CD2  1 
ATOM   319  C CE1  . PHE A 1 22  ? 121.169 97.082  111.663 1.00 53.45  ? 22  PHE A CE1  1 
ATOM   320  C CE2  . PHE A 1 22  ? 120.530 95.080  112.785 1.00 53.45  ? 22  PHE A CE2  1 
ATOM   321  C CZ   . PHE A 1 22  ? 120.265 96.066  111.860 1.00 53.45  ? 22  PHE A CZ   1 
ATOM   322  H H    . PHE A 1 22  ? 125.554 96.470  115.889 1.00 53.45  ? 22  PHE A H    1 
ATOM   323  H HA   . PHE A 1 22  ? 123.664 98.025  114.968 1.00 53.45  ? 22  PHE A HA   1 
ATOM   324  H HB2  . PHE A 1 22  ? 124.598 96.477  113.534 1.00 53.45  ? 22  PHE A HB2  1 
ATOM   325  H HB3  . PHE A 1 22  ? 124.062 95.288  114.442 1.00 53.45  ? 22  PHE A HB3  1 
ATOM   326  H HD1  . PHE A 1 22  ? 122.943 97.804  112.254 1.00 53.45  ? 22  PHE A HD1  1 
ATOM   327  H HD2  . PHE A 1 22  ? 121.873 94.449  114.136 1.00 53.45  ? 22  PHE A HD2  1 
ATOM   328  H HE1  . PHE A 1 22  ? 120.992 97.748  111.038 1.00 53.45  ? 22  PHE A HE1  1 
ATOM   329  H HE2  . PHE A 1 22  ? 119.919 94.392  112.919 1.00 53.45  ? 22  PHE A HE2  1 
ATOM   330  H HZ   . PHE A 1 22  ? 119.477 96.043  111.368 1.00 53.45  ? 22  PHE A HZ   1 
ATOM   331  N N    . LEU A 1 23  ? 122.662 95.811  117.039 1.00 55.57  ? 23  LEU A N    1 
ATOM   332  C CA   . LEU A 1 23  ? 121.516 95.478  117.876 1.00 55.57  ? 23  LEU A CA   1 
ATOM   333  C C    . LEU A 1 23  ? 121.072 96.695  118.674 1.00 55.57  ? 23  LEU A C    1 
ATOM   334  O O    . LEU A 1 23  ? 119.878 97.011  118.741 1.00 55.57  ? 23  LEU A O    1 
ATOM   335  C CB   . LEU A 1 23  ? 121.861 94.322  118.814 1.00 55.57  ? 23  LEU A CB   1 
ATOM   336  C CG   . LEU A 1 23  ? 120.671 93.685  119.536 1.00 55.57  ? 23  LEU A CG   1 
ATOM   337  C CD1  . LEU A 1 23  ? 120.733 92.172  119.434 1.00 55.57  ? 23  LEU A CD1  1 
ATOM   338  C CD2  . LEU A 1 23  ? 120.620 94.114  120.994 1.00 55.57  ? 23  LEU A CD2  1 
ATOM   339  H H    . LEU A 1 23  ? 123.371 95.350  117.192 1.00 55.57  ? 23  LEU A H    1 
ATOM   340  H HA   . LEU A 1 23  ? 120.779 95.197  117.311 1.00 55.57  ? 23  LEU A HA   1 
ATOM   341  H HB2  . LEU A 1 23  ? 122.316 93.629  118.311 1.00 55.57  ? 23  LEU A HB2  1 
ATOM   342  H HB3  . LEU A 1 23  ? 122.455 94.667  119.500 1.00 55.57  ? 23  LEU A HB3  1 
ATOM   343  H HG   . LEU A 1 23  ? 119.850 93.980  119.111 1.00 55.57  ? 23  LEU A HG   1 
ATOM   344  H HD11 . LEU A 1 23  ? 120.011 91.794  119.960 1.00 55.57  ? 23  LEU A HD11 1 
ATOM   345  H HD12 . LEU A 1 23  ? 120.636 91.912  118.505 1.00 55.57  ? 23  LEU A HD12 1 
ATOM   346  H HD13 . LEU A 1 23  ? 121.587 91.867  119.777 1.00 55.57  ? 23  LEU A HD13 1 
ATOM   347  H HD21 . LEU A 1 23  ? 119.839 93.718  121.412 1.00 55.57  ? 23  LEU A HD21 1 
ATOM   348  H HD22 . LEU A 1 23  ? 121.425 93.808  121.441 1.00 55.57  ? 23  LEU A HD22 1 
ATOM   349  H HD23 . LEU A 1 23  ? 120.564 95.081  121.039 1.00 55.57  ? 23  LEU A HD23 1 
ATOM   350  N N    . THR A 1 24  ? 122.028 97.406  119.274 1.00 55.71  ? 24  THR A N    1 
ATOM   351  C CA   . THR A 1 24  ? 121.659 98.590  120.046 1.00 55.71  ? 24  THR A CA   1 
ATOM   352  C C    . THR A 1 24  ? 121.048 99.664  119.152 1.00 55.71  ? 24  THR A C    1 
ATOM   353  O O    . THR A 1 24  ? 120.026 100.269 119.500 1.00 55.71  ? 24  THR A O    1 
ATOM   354  C CB   . THR A 1 24  ? 122.872 99.145  120.789 1.00 55.71  ? 24  THR A CB   1 
ATOM   355  O OG1  . THR A 1 24  ? 123.561 98.077  121.448 1.00 55.71  ? 24  THR A OG1  1 
ATOM   356  C CG2  . THR A 1 24  ? 122.439 100.159 121.830 1.00 55.71  ? 24  THR A CG2  1 
ATOM   357  H H    . THR A 1 24  ? 122.869 97.234  119.249 1.00 55.71  ? 24  THR A H    1 
ATOM   358  H HA   . THR A 1 24  ? 120.991 98.339  120.706 1.00 55.71  ? 24  THR A HA   1 
ATOM   359  H HB   . THR A 1 24  ? 123.463 99.587  120.160 1.00 55.71  ? 24  THR A HB   1 
ATOM   360  H HG1  . THR A 1 24  ? 123.954 97.595  120.886 1.00 55.71  ? 24  THR A HG1  1 
ATOM   361  H HG21 . THR A 1 24  ? 123.220 100.508 122.288 1.00 55.71  ? 24  THR A HG21 1 
ATOM   362  H HG22 . THR A 1 24  ? 121.966 100.896 121.413 1.00 55.71  ? 24  THR A HG22 1 
ATOM   363  H HG23 . THR A 1 24  ? 121.856 99.732  122.477 1.00 55.71  ? 24  THR A HG23 1 
ATOM   364  N N    . LEU A 1 25  ? 121.645 99.911  117.984 1.00 50.23  ? 25  LEU A N    1 
ATOM   365  C CA   . LEU A 1 25  ? 121.127 100.985 117.142 1.00 50.23  ? 25  LEU A CA   1 
ATOM   366  C C    . LEU A 1 25  ? 119.759 100.624 116.579 1.00 50.23  ? 25  LEU A C    1 
ATOM   367  O O    . LEU A 1 25  ? 118.910 101.499 116.387 1.00 50.23  ? 25  LEU A O    1 
ATOM   368  C CB   . LEU A 1 25  ? 122.114 101.315 116.028 1.00 50.23  ? 25  LEU A CB   1 
ATOM   369  C CG   . LEU A 1 25  ? 123.085 102.440 116.396 1.00 50.23  ? 25  LEU A CG   1 
ATOM   370  C CD1  . LEU A 1 25  ? 122.363 103.775 116.526 1.00 50.23  ? 25  LEU A CD1  1 
ATOM   371  C CD2  . LEU A 1 25  ? 123.832 102.117 117.677 1.00 50.23  ? 25  LEU A CD2  1 
ATOM   372  H H    . LEU A 1 25  ? 122.317 99.481  117.660 1.00 50.23  ? 25  LEU A H    1 
ATOM   373  H HA   . LEU A 1 25  ? 121.015 101.778 117.687 1.00 50.23  ? 25  LEU A HA   1 
ATOM   374  H HB2  . LEU A 1 25  ? 122.633 100.521 115.818 1.00 50.23  ? 25  LEU A HB2  1 
ATOM   375  H HB3  . LEU A 1 25  ? 121.615 101.598 115.246 1.00 50.23  ? 25  LEU A HB3  1 
ATOM   376  H HG   . LEU A 1 25  ? 123.739 102.533 115.690 1.00 50.23  ? 25  LEU A HG   1 
ATOM   377  H HD11 . LEU A 1 25  ? 123.022 104.487 116.539 1.00 50.23  ? 25  LEU A HD11 1 
ATOM   378  H HD12 . LEU A 1 25  ? 121.769 103.893 115.768 1.00 50.23  ? 25  LEU A HD12 1 
ATOM   379  H HD13 . LEU A 1 25  ? 121.853 103.785 117.350 1.00 50.23  ? 25  LEU A HD13 1 
ATOM   380  H HD21 . LEU A 1 25  ? 124.538 102.771 117.801 1.00 50.23  ? 25  LEU A HD21 1 
ATOM   381  H HD22 . LEU A 1 25  ? 123.217 102.152 118.427 1.00 50.23  ? 25  LEU A HD22 1 
ATOM   382  H HD23 . LEU A 1 25  ? 124.216 101.230 117.606 1.00 50.23  ? 25  LEU A HD23 1 
ATOM   383  N N    . CYS A 1 26  ? 119.525 99.344  116.302 1.00 50.32  ? 26  CYS A N    1 
ATOM   384  C CA   . CYS A 1 26  ? 118.190 98.889  115.944 1.00 50.32  ? 26  CYS A CA   1 
ATOM   385  C C    . CYS A 1 26  ? 117.199 99.068  117.086 1.00 50.32  ? 26  CYS A C    1 
ATOM   386  O O    . CYS A 1 26  ? 116.070 99.508  116.848 1.00 50.32  ? 26  CYS A O    1 
ATOM   387  C CB   . CYS A 1 26  ? 118.257 97.421  115.526 1.00 50.32  ? 26  CYS A CB   1 
ATOM   388  S SG   . CYS A 1 26  ? 116.723 96.493  115.709 1.00 50.32  ? 26  CYS A SG   1 
ATOM   389  H H    . CYS A 1 26  ? 120.126 98.729  116.309 1.00 50.32  ? 26  CYS A H    1 
ATOM   390  H HA   . CYS A 1 26  ? 117.880 99.404  115.184 1.00 50.32  ? 26  CYS A HA   1 
ATOM   391  H HB2  . CYS A 1 26  ? 118.511 97.370  114.591 1.00 50.32  ? 26  CYS A HB2  1 
ATOM   392  H HB3  . CYS A 1 26  ? 118.937 96.989  116.073 1.00 50.32  ? 26  CYS A HB3  1 
ATOM   393  H HG   . CYS A 1 26  ? 116.504 96.246  116.857 1.00 50.32  ? 26  CYS A HG   1 
ATOM   394  N N    . LEU A 1 27  ? 117.612 98.791  118.323 1.00 51.45  ? 27  LEU A N    1 
ATOM   395  C CA   . LEU A 1 27  ? 116.748 99.079  119.462 1.00 51.45  ? 27  LEU A CA   1 
ATOM   396  C C    . LEU A 1 27  ? 116.394 100.557 119.494 1.00 51.45  ? 27  LEU A C    1 
ATOM   397  O O    . LEU A 1 27  ? 115.281 100.931 119.878 1.00 51.45  ? 27  LEU A O    1 
ATOM   398  C CB   . LEU A 1 27  ? 117.428 98.657  120.764 1.00 51.45  ? 27  LEU A CB   1 
ATOM   399  C CG   . LEU A 1 27  ? 116.566 98.546  122.026 1.00 51.45  ? 27  LEU A CG   1 
ATOM   400  C CD1  . LEU A 1 27  ? 117.308 97.751  123.089 1.00 51.45  ? 27  LEU A CD1  1 
ATOM   401  C CD2  . LEU A 1 27  ? 116.177 99.917  122.568 1.00 51.45  ? 27  LEU A CD2  1 
ATOM   402  H H    . LEU A 1 27  ? 118.371 98.439  118.518 1.00 51.45  ? 27  LEU A H    1 
ATOM   403  H HA   . LEU A 1 27  ? 115.929 98.568  119.366 1.00 51.45  ? 27  LEU A HA   1 
ATOM   404  H HB2  . LEU A 1 27  ? 117.838 97.791  120.621 1.00 51.45  ? 27  LEU A HB2  1 
ATOM   405  H HB3  . LEU A 1 27  ? 118.124 99.304  120.958 1.00 51.45  ? 27  LEU A HB3  1 
ATOM   406  H HG   . LEU A 1 27  ? 115.751 98.067  121.810 1.00 51.45  ? 27  LEU A HG   1 
ATOM   407  H HD11 . LEU A 1 27  ? 116.749 97.676  123.878 1.00 51.45  ? 27  LEU A HD11 1 
ATOM   408  H HD12 . LEU A 1 27  ? 117.508 96.867  122.742 1.00 51.45  ? 27  LEU A HD12 1 
ATOM   409  H HD13 . LEU A 1 27  ? 118.132 98.213  123.309 1.00 51.45  ? 27  LEU A HD13 1 
ATOM   410  H HD21 . LEU A 1 27  ? 115.992 99.839  123.517 1.00 51.45  ? 27  LEU A HD21 1 
ATOM   411  H HD22 . LEU A 1 27  ? 116.912 100.534 122.425 1.00 51.45  ? 27  LEU A HD22 1 
ATOM   412  H HD23 . LEU A 1 27  ? 115.386 100.232 122.105 1.00 51.45  ? 27  LEU A HD23 1 
ATOM   413  N N    . LEU A 1 28  ? 117.335 101.413 119.096 1.00 47.52  ? 28  LEU A N    1 
ATOM   414  C CA   . LEU A 1 28  ? 117.015 102.832 118.950 1.00 47.52  ? 28  LEU A CA   1 
ATOM   415  C C    . LEU A 1 28  ? 116.092 103.085 117.765 1.00 47.52  ? 28  LEU A C    1 
ATOM   416  O O    . LEU A 1 28  ? 115.330 104.056 117.775 1.00 47.52  ? 28  LEU A O    1 
ATOM   417  C CB   . LEU A 1 28  ? 118.285 103.665 118.781 1.00 47.52  ? 28  LEU A CB   1 
ATOM   418  C CG   . LEU A 1 28  ? 118.071 105.101 118.286 1.00 47.52  ? 28  LEU A CG   1 
ATOM   419  C CD1  . LEU A 1 28  ? 117.198 105.906 119.244 1.00 47.52  ? 28  LEU A CD1  1 
ATOM   420  C CD2  . LEU A 1 28  ? 119.409 105.772 118.093 1.00 47.52  ? 28  LEU A CD2  1 
ATOM   421  H H    . LEU A 1 28  ? 118.150 101.201 118.918 1.00 47.52  ? 28  LEU A H    1 
ATOM   422  H HA   . LEU A 1 28  ? 116.567 103.136 119.752 1.00 47.52  ? 28  LEU A HA   1 
ATOM   423  H HB2  . LEU A 1 28  ? 118.736 103.718 119.637 1.00 47.52  ? 28  LEU A HB2  1 
ATOM   424  H HB3  . LEU A 1 28  ? 118.861 103.222 118.140 1.00 47.52  ? 28  LEU A HB3  1 
ATOM   425  H HG   . LEU A 1 28  ? 117.634 105.089 117.421 1.00 47.52  ? 28  LEU A HG   1 
ATOM   426  H HD11 . LEU A 1 28  ? 116.920 106.725 118.806 1.00 47.52  ? 28  LEU A HD11 1 
ATOM   427  H HD12 . LEU A 1 28  ? 116.418 105.385 119.489 1.00 47.52  ? 28  LEU A HD12 1 
ATOM   428  H HD13 . LEU A 1 28  ? 117.713 106.116 120.039 1.00 47.52  ? 28  LEU A HD13 1 
ATOM   429  H HD21 . LEU A 1 28  ? 119.270 106.661 117.733 1.00 47.52  ? 28  LEU A HD21 1 
ATOM   430  H HD22 . LEU A 1 28  ? 119.857 105.825 118.951 1.00 47.52  ? 28  LEU A HD22 1 
ATOM   431  H HD23 . LEU A 1 28  ? 119.938 105.243 117.476 1.00 47.52  ? 28  LEU A HD23 1 
ATOM   432  N N    . SER A 1 29  ? 116.153 102.238 116.736 1.00 44.69  ? 29  SER A N    1 
ATOM   433  C CA   . SER A 1 29  ? 115.427 102.522 115.502 1.00 44.69  ? 29  SER A CA   1 
ATOM   434  C C    . SER A 1 29  ? 113.931 102.624 115.747 1.00 44.69  ? 29  SER A C    1 
ATOM   435  O O    . SER A 1 29  ? 113.266 103.511 115.202 1.00 44.69  ? 29  SER A O    1 
ATOM   436  C CB   . SER A 1 29  ? 115.712 101.439 114.464 1.00 44.69  ? 29  SER A CB   1 
ATOM   437  O OG   . SER A 1 29  ? 115.064 100.229 114.812 1.00 44.69  ? 29  SER A OG   1 
ATOM   438  H H    . SER A 1 29  ? 116.598 101.503 116.729 1.00 44.69  ? 29  SER A H    1 
ATOM   439  H HA   . SER A 1 29  ? 115.733 103.369 115.144 1.00 44.69  ? 29  SER A HA   1 
ATOM   440  H HB2  . SER A 1 29  ? 115.382 101.734 113.601 1.00 44.69  ? 29  SER A HB2  1 
ATOM   441  H HB3  . SER A 1 29  ? 116.669 101.286 114.420 1.00 44.69  ? 29  SER A HB3  1 
ATOM   442  H HG   . SER A 1 29  ? 115.173 100.073 115.629 1.00 44.69  ? 29  SER A HG   1 
ATOM   443  N N    . ALA A 1 30  ? 113.381 101.729 116.568 1.00 42.44  ? 30  ALA A N    1 
ATOM   444  C CA   . ALA A 1 30  ? 111.936 101.698 116.754 1.00 42.44  ? 30  ALA A CA   1 
ATOM   445  C C    . ALA A 1 30  ? 111.420 102.997 117.355 1.00 42.44  ? 30  ALA A C    1 
ATOM   446  O O    . ALA A 1 30  ? 110.279 103.391 117.091 1.00 42.44  ? 30  ALA A O    1 
ATOM   447  C CB   . ALA A 1 30  ? 111.543 100.512 117.636 1.00 42.44  ? 30  ALA A CB   1 
ATOM   448  H H    . ALA A 1 30  ? 113.816 101.145 117.026 1.00 42.44  ? 30  ALA A H    1 
ATOM   449  H HA   . ALA A 1 30  ? 111.513 101.578 115.890 1.00 42.44  ? 30  ALA A HA   1 
ATOM   450  H HB1  . ALA A 1 30  ? 110.580 100.510 117.750 1.00 42.44  ? 30  ALA A HB1  1 
ATOM   451  H HB2  . ALA A 1 30  ? 111.825 99.690  117.205 1.00 42.44  ? 30  ALA A HB2  1 
ATOM   452  H HB3  . ALA A 1 30  ? 111.977 100.597 118.499 1.00 42.44  ? 30  ALA A HB3  1 
ATOM   453  N N    . ALA A 1 31  ? 112.247 103.687 118.141 1.00 43.29  ? 31  ALA A N    1 
ATOM   454  C CA   . ALA A 1 31  ? 111.790 104.883 118.838 1.00 43.29  ? 31  ALA A CA   1 
ATOM   455  C C    . ALA A 1 31  ? 111.299 105.959 117.883 1.00 43.29  ? 31  ALA A C    1 
ATOM   456  O O    . ALA A 1 31  ? 110.565 106.856 118.308 1.00 43.29  ? 31  ALA A O    1 
ATOM   457  C CB   . ALA A 1 31  ? 112.911 105.447 119.708 1.00 43.29  ? 31  ALA A CB   1 
ATOM   458  H H    . ALA A 1 31  ? 113.071 103.485 118.284 1.00 43.29  ? 31  ALA A H    1 
ATOM   459  H HA   . ALA A 1 31  ? 111.052 104.643 119.420 1.00 43.29  ? 31  ALA A HA   1 
ATOM   460  H HB1  . ALA A 1 31  ? 112.607 106.273 120.115 1.00 43.29  ? 31  ALA A HB1  1 
ATOM   461  H HB2  . ALA A 1 31  ? 113.136 104.800 120.396 1.00 43.29  ? 31  ALA A HB2  1 
ATOM   462  H HB3  . ALA A 1 31  ? 113.685 105.622 119.150 1.00 43.29  ? 31  ALA A HB3  1 
ATOM   463  N N    . PHE A 1 32  ? 111.699 105.909 116.615 1.00 39.74  ? 32  PHE A N    1 
ATOM   464  C CA   . PHE A 1 32  ? 111.240 106.894 115.647 1.00 39.74  ? 32  PHE A CA   1 
ATOM   465  C C    . PHE A 1 32  ? 109.860 106.576 115.091 1.00 39.74  ? 32  PHE A C    1 
ATOM   466  O O    . PHE A 1 32  ? 109.278 107.427 114.412 1.00 39.74  ? 32  PHE A O    1 
ATOM   467  C CB   . PHE A 1 32  ? 112.242 107.006 114.497 1.00 39.74  ? 32  PHE A CB   1 
ATOM   468  C CG   . PHE A 1 32  ? 111.933 108.109 113.529 1.00 39.74  ? 32  PHE A CG   1 
ATOM   469  C CD1  . PHE A 1 32  ? 112.042 109.430 113.911 1.00 39.74  ? 32  PHE A CD1  1 
ATOM   470  C CD2  . PHE A 1 32  ? 111.544 107.825 112.235 1.00 39.74  ? 32  PHE A CD2  1 
ATOM   471  C CE1  . PHE A 1 32  ? 111.763 110.446 113.025 1.00 39.74  ? 32  PHE A CE1  1 
ATOM   472  C CE2  . PHE A 1 32  ? 111.267 108.837 111.345 1.00 39.74  ? 32  PHE A CE2  1 
ATOM   473  C CZ   . PHE A 1 32  ? 111.374 110.148 111.741 1.00 39.74  ? 32  PHE A CZ   1 
ATOM   474  H H    . PHE A 1 32  ? 112.232 105.316 116.293 1.00 39.74  ? 32  PHE A H    1 
ATOM   475  H HA   . PHE A 1 32  ? 111.191 107.760 116.082 1.00 39.74  ? 32  PHE A HA   1 
ATOM   476  H HB2  . PHE A 1 32  ? 113.124 107.171 114.865 1.00 39.74  ? 32  PHE A HB2  1 
ATOM   477  H HB3  . PHE A 1 32  ? 112.244 106.171 114.003 1.00 39.74  ? 32  PHE A HB3  1 
ATOM   478  H HD1  . PHE A 1 32  ? 112.304 109.636 114.779 1.00 39.74  ? 32  PHE A HD1  1 
ATOM   479  H HD2  . PHE A 1 32  ? 111.469 106.939 111.961 1.00 39.74  ? 32  PHE A HD2  1 
ATOM   480  H HE1  . PHE A 1 32  ? 111.837 111.333 113.294 1.00 39.74  ? 32  PHE A HE1  1 
ATOM   481  H HE2  . PHE A 1 32  ? 111.003 108.634 110.476 1.00 39.74  ? 32  PHE A HE2  1 
ATOM   482  H HZ   . PHE A 1 32  ? 111.186 110.833 111.141 1.00 39.74  ? 32  PHE A HZ   1 
ATOM   483  N N    . ALA A 1 33  ? 109.328 105.383 115.345 1.00 39.31  ? 33  ALA A N    1 
ATOM   484  C CA   . ALA A 1 33  ? 107.995 105.057 114.843 1.00 39.31  ? 33  ALA A CA   1 
ATOM   485  C C    . ALA A 1 33  ? 106.909 105.928 115.459 1.00 39.31  ? 33  ALA A C    1 
ATOM   486  O O    . ALA A 1 33  ? 106.085 106.473 114.704 1.00 39.31  ? 33  ALA A O    1 
ATOM   487  C CB   . ALA A 1 33  ? 107.711 103.569 115.063 1.00 39.31  ? 33  ALA A CB   1 
ATOM   488  H H    . ALA A 1 33  ? 109.708 104.755 115.794 1.00 39.31  ? 33  ALA A H    1 
ATOM   489  H HA   . ALA A 1 33  ? 107.982 105.215 113.886 1.00 39.31  ? 33  ALA A HA   1 
ATOM   490  H HB1  . ALA A 1 33  ? 106.769 103.402 114.902 1.00 39.31  ? 33  ALA A HB1  1 
ATOM   491  H HB2  . ALA A 1 33  ? 108.247 103.052 114.441 1.00 39.31  ? 33  ALA A HB2  1 
ATOM   492  H HB3  . ALA A 1 33  ? 107.936 103.323 115.972 1.00 39.31  ? 33  ALA A HB3  1 
ATOM   493  N N    . PRO A 1 34  ? 106.831 106.104 116.781 1.00 39.98  ? 34  PRO A N    1 
ATOM   494  C CA   . PRO A 1 34  ? 105.758 106.950 117.331 1.00 39.98  ? 34  PRO A CA   1 
ATOM   495  C C    . PRO A 1 34  ? 105.751 108.371 116.800 1.00 39.98  ? 34  PRO A C    1 
ATOM   496  O O    . PRO A 1 34  ? 104.671 108.929 116.574 1.00 39.98  ? 34  PRO A O    1 
ATOM   497  C CB   . PRO A 1 34  ? 106.030 106.914 118.840 1.00 39.98  ? 34  PRO A CB   1 
ATOM   498  C CG   . PRO A 1 34  ? 106.743 105.645 119.061 1.00 39.98  ? 34  PRO A CG   1 
ATOM   499  C CD   . PRO A 1 34  ? 107.592 105.433 117.847 1.00 39.98  ? 34  PRO A CD   1 
ATOM   500  H HA   . PRO A 1 34  ? 104.893 106.556 117.154 1.00 39.98  ? 34  PRO A HA   1 
ATOM   501  H HB2  . PRO A 1 34  ? 106.586 107.669 119.089 1.00 39.98  ? 34  PRO A HB2  1 
ATOM   502  H HB3  . PRO A 1 34  ? 105.191 106.929 119.325 1.00 39.98  ? 34  PRO A HB3  1 
ATOM   503  H HG2  . PRO A 1 34  ? 107.296 105.719 119.855 1.00 39.98  ? 34  PRO A HG2  1 
ATOM   504  H HG3  . PRO A 1 34  ? 106.101 104.926 119.160 1.00 39.98  ? 34  PRO A HG3  1 
ATOM   505  H HD2  . PRO A 1 34  ? 108.457 105.854 117.961 1.00 39.98  ? 34  PRO A HD2  1 
ATOM   506  H HD3  . PRO A 1 34  ? 107.678 104.486 117.671 1.00 39.98  ? 34  PRO A HD3  1 
ATOM   507  N N    . ILE A 1 35  ? 106.917 108.982 116.596 1.00 39.53  ? 35  ILE A N    1 
ATOM   508  C CA   . ILE A 1 35  ? 106.927 110.362 116.128 1.00 39.53  ? 35  ILE A CA   1 
ATOM   509  C C    . ILE A 1 35  ? 106.621 110.432 114.639 1.00 39.53  ? 35  ILE A C    1 
ATOM   510  O O    . ILE A 1 35  ? 106.040 111.416 114.169 1.00 39.53  ? 35  ILE A O    1 
ATOM   511  C CB   . ILE A 1 35  ? 108.272 111.036 116.446 1.00 39.53  ? 35  ILE A CB   1 
ATOM   512  C CG1  . ILE A 1 35  ? 108.450 111.198 117.956 1.00 39.53  ? 35  ILE A CG1  1 
ATOM   513  C CG2  . ILE A 1 35  ? 108.357 112.385 115.757 1.00 39.53  ? 35  ILE A CG2  1 
ATOM   514  C CD1  . ILE A 1 35  ? 109.037 109.989 118.643 1.00 39.53  ? 35  ILE A CD1  1 
ATOM   515  H H    . ILE A 1 35  ? 107.692 108.630 116.715 1.00 39.53  ? 35  ILE A H    1 
ATOM   516  H HA   . ILE A 1 35  ? 106.233 110.854 116.594 1.00 39.53  ? 35  ILE A HA   1 
ATOM   517  H HB   . ILE A 1 35  ? 108.986 110.473 116.110 1.00 39.53  ? 35  ILE A HB   1 
ATOM   518  H HG12 . ILE A 1 35  ? 109.046 111.944 118.124 1.00 39.53  ? 35  ILE A HG12 1 
ATOM   519  H HG13 . ILE A 1 35  ? 107.585 111.374 118.357 1.00 39.53  ? 35  ILE A HG13 1 
ATOM   520  H HG21 . ILE A 1 35  ? 109.034 112.926 116.194 1.00 39.53  ? 35  ILE A HG21 1 
ATOM   521  H HG22 . ILE A 1 35  ? 108.599 112.250 114.828 1.00 39.53  ? 35  ILE A HG22 1 
ATOM   522  H HG23 . ILE A 1 35  ? 107.496 112.826 115.817 1.00 39.53  ? 35  ILE A HG23 1 
ATOM   523  H HD11 . ILE A 1 35  ? 109.227 110.215 119.567 1.00 39.53  ? 35  ILE A HD11 1 
ATOM   524  H HD12 . ILE A 1 35  ? 108.402 109.258 118.608 1.00 39.53  ? 35  ILE A HD12 1 
ATOM   525  H HD13 . ILE A 1 35  ? 109.858 109.738 118.191 1.00 39.53  ? 35  ILE A HD13 1 
ATOM   526  N N    . TYR A 1 36  ? 107.001 109.409 113.875 1.00 40.35  ? 36  TYR A N    1 
ATOM   527  C CA   . TYR A 1 36  ? 106.782 109.433 112.435 1.00 40.35  ? 36  TYR A CA   1 
ATOM   528  C C    . TYR A 1 36  ? 105.370 109.017 112.057 1.00 40.35  ? 36  TYR A C    1 
ATOM   529  O O    . TYR A 1 36  ? 104.856 109.465 111.027 1.00 40.35  ? 36  TYR A O    1 
ATOM   530  C CB   . TYR A 1 36  ? 107.786 108.518 111.738 1.00 40.35  ? 36  TYR A CB   1 
ATOM   531  C CG   . TYR A 1 36  ? 107.571 108.401 110.249 1.00 40.35  ? 36  TYR A CG   1 
ATOM   532  C CD1  . TYR A 1 36  ? 108.139 109.312 109.374 1.00 40.35  ? 36  TYR A CD1  1 
ATOM   533  C CD2  . TYR A 1 36  ? 106.802 107.376 109.719 1.00 40.35  ? 36  TYR A CD2  1 
ATOM   534  C CE1  . TYR A 1 36  ? 107.947 109.209 108.012 1.00 40.35  ? 36  TYR A CE1  1 
ATOM   535  C CE2  . TYR A 1 36  ? 106.603 107.264 108.359 1.00 40.35  ? 36  TYR A CE2  1 
ATOM   536  C CZ   . TYR A 1 36  ? 107.178 108.182 107.510 1.00 40.35  ? 36  TYR A CZ   1 
ATOM   537  O OH   . TYR A 1 36  ? 106.983 108.073 106.153 1.00 40.35  ? 36  TYR A OH   1 
ATOM   538  H H    . TYR A 1 36  ? 107.385 108.696 114.165 1.00 40.35  ? 36  TYR A H    1 
ATOM   539  H HA   . TYR A 1 36  ? 106.925 110.335 112.109 1.00 40.35  ? 36  TYR A HA   1 
ATOM   540  H HB2  . TYR A 1 36  ? 108.674 108.872 111.884 1.00 40.35  ? 36  TYR A HB2  1 
ATOM   541  H HB3  . TYR A 1 36  ? 107.718 107.629 112.120 1.00 40.35  ? 36  TYR A HB3  1 
ATOM   542  H HD1  . TYR A 1 36  ? 108.659 110.006 109.711 1.00 40.35  ? 36  TYR A HD1  1 
ATOM   543  H HD2  . TYR A 1 36  ? 106.412 106.754 110.290 1.00 40.35  ? 36  TYR A HD2  1 
ATOM   544  H HE1  . TYR A 1 36  ? 108.335 109.828 107.437 1.00 40.35  ? 36  TYR A HE1  1 
ATOM   545  H HE2  . TYR A 1 36  ? 106.084 106.572 108.018 1.00 40.35  ? 36  TYR A HE2  1 
ATOM   546  H HH   . TYR A 1 36  ? 107.410 108.676 105.753 1.00 40.35  ? 36  TYR A HH   1 
ATOM   547  N N    . VAL A 1 37  ? 104.730 108.165 112.860 1.00 39.94  ? 37  VAL A N    1 
ATOM   548  C CA   . VAL A 1 37  ? 103.399 107.686 112.505 1.00 39.94  ? 37  VAL A CA   1 
ATOM   549  C C    . VAL A 1 37  ? 102.443 108.856 112.361 1.00 39.94  ? 37  VAL A C    1 
ATOM   550  O O    . VAL A 1 37  ? 101.479 108.790 111.590 1.00 39.94  ? 37  VAL A O    1 
ATOM   551  C CB   . VAL A 1 37  ? 102.898 106.671 113.550 1.00 39.94  ? 37  VAL A CB   1 
ATOM   552  C CG1  . VAL A 1 37  ? 102.402 107.389 114.797 1.00 39.94  ? 37  VAL A CG1  1 
ATOM   553  C CG2  . VAL A 1 37  ? 101.811 105.784 112.961 1.00 39.94  ? 37  VAL A CG2  1 
ATOM   554  H H    . VAL A 1 37  ? 105.039 107.856 113.601 1.00 39.94  ? 37  VAL A H    1 
ATOM   555  H HA   . VAL A 1 37  ? 103.452 107.237 111.647 1.00 39.94  ? 37  VAL A HA   1 
ATOM   556  H HB   . VAL A 1 37  ? 103.637 106.100 113.811 1.00 39.94  ? 37  VAL A HB   1 
ATOM   557  H HG11 . VAL A 1 37  ? 102.354 106.753 115.528 1.00 39.94  ? 37  VAL A HG11 1 
ATOM   558  H HG12 . VAL A 1 37  ? 103.023 108.100 115.018 1.00 39.94  ? 37  VAL A HG12 1 
ATOM   559  H HG13 . VAL A 1 37  ? 101.523 107.761 114.626 1.00 39.94  ? 37  VAL A HG13 1 
ATOM   560  H HG21 . VAL A 1 37  ? 102.062 104.856 113.091 1.00 39.94  ? 37  VAL A HG21 1 
ATOM   561  H HG22 . VAL A 1 37  ? 100.973 105.964 113.415 1.00 39.94  ? 37  VAL A HG22 1 
ATOM   562  H HG23 . VAL A 1 37  ? 101.722 105.970 112.014 1.00 39.94  ? 37  VAL A HG23 1 
ATOM   563  N N    . GLY A 1 38  ? 102.686 109.936 113.092 1.00 40.11  ? 38  GLY A N    1 
ATOM   564  C CA   . GLY A 1 38  ? 101.885 111.132 112.960 1.00 40.11  ? 38  GLY A CA   1 
ATOM   565  C C    . GLY A 1 38  ? 100.740 111.176 113.951 1.00 40.11  ? 38  GLY A C    1 
ATOM   566  O O    . GLY A 1 38  ? 100.752 110.546 115.011 1.00 40.11  ? 38  GLY A O    1 
ATOM   567  H H    . GLY A 1 38  ? 103.314 109.997 113.675 1.00 40.11  ? 38  GLY A H    1 
ATOM   568  H HA2  . GLY A 1 38  ? 102.445 111.910 113.106 1.00 40.11  ? 38  GLY A HA2  1 
ATOM   569  H HA3  . GLY A 1 38  ? 101.518 111.182 112.064 1.00 40.11  ? 38  GLY A HA3  1 
ATOM   570  N N    . ILE A 1 39  ? 99.722  111.952 113.581 1.00 45.78  ? 39  ILE A N    1 
ATOM   571  C CA   . ILE A 1 39  ? 98.576  112.141 114.461 1.00 45.78  ? 39  ILE A CA   1 
ATOM   572  C C    . ILE A 1 39  ? 97.800  110.840 114.637 1.00 45.78  ? 39  ILE A C    1 
ATOM   573  O O    . ILE A 1 39  ? 97.144  110.640 115.667 1.00 45.78  ? 39  ILE A O    1 
ATOM   574  C CB   . ILE A 1 39  ? 97.683  113.272 113.916 1.00 45.78  ? 39  ILE A CB   1 
ATOM   575  C CG1  . ILE A 1 39  ? 96.595  113.639 114.924 1.00 45.78  ? 39  ILE A CG1  1 
ATOM   576  C CG2  . ILE A 1 39  ? 97.054  112.874 112.590 1.00 45.78  ? 39  ILE A CG2  1 
ATOM   577  C CD1  . ILE A 1 39  ? 97.125  114.278 116.183 1.00 45.78  ? 39  ILE A CD1  1 
ATOM   578  H H    . ILE A 1 39  ? 99.672  112.375 112.834 1.00 45.78  ? 39  ILE A H    1 
ATOM   579  H HA   . ILE A 1 39  ? 98.900  112.410 115.335 1.00 45.78  ? 39  ILE A HA   1 
ATOM   580  H HB   . ILE A 1 39  ? 98.238  114.054 113.768 1.00 45.78  ? 39  ILE A HB   1 
ATOM   581  H HG12 . ILE A 1 39  ? 95.983  114.266 114.507 1.00 45.78  ? 39  ILE A HG12 1 
ATOM   582  H HG13 . ILE A 1 39  ? 96.117  112.835 115.175 1.00 45.78  ? 39  ILE A HG13 1 
ATOM   583  H HG21 . ILE A 1 39  ? 96.625  113.653 112.202 1.00 45.78  ? 39  ILE A HG21 1 
ATOM   584  H HG22 . ILE A 1 39  ? 97.747  112.550 111.994 1.00 45.78  ? 39  ILE A HG22 1 
ATOM   585  H HG23 . ILE A 1 39  ? 96.397  112.179 112.745 1.00 45.78  ? 39  ILE A HG23 1 
ATOM   586  H HD11 . ILE A 1 39  ? 96.384  114.665 116.675 1.00 45.78  ? 39  ILE A HD11 1 
ATOM   587  H HD12 . ILE A 1 39  ? 97.562  113.600 116.721 1.00 45.78  ? 39  ILE A HD12 1 
ATOM   588  H HD13 . ILE A 1 39  ? 97.759  114.972 115.941 1.00 45.78  ? 39  ILE A HD13 1 
ATOM   589  N N    . VAL A 1 40  ? 97.859  109.937 113.654 1.00 43.89  ? 40  VAL A N    1 
ATOM   590  C CA   . VAL A 1 40  ? 97.076  108.707 113.721 1.00 43.89  ? 40  VAL A CA   1 
ATOM   591  C C    . VAL A 1 40  ? 97.439  107.933 114.981 1.00 43.89  ? 40  VAL A C    1 
ATOM   592  O O    . VAL A 1 40  ? 98.593  107.940 115.428 1.00 43.89  ? 40  VAL A O    1 
ATOM   593  C CB   . VAL A 1 40  ? 97.303  107.861 112.458 1.00 43.89  ? 40  VAL A CB   1 
ATOM   594  C CG1  . VAL A 1 40  ? 98.702  107.273 112.455 1.00 43.89  ? 40  VAL A CG1  1 
ATOM   595  C CG2  . VAL A 1 40  ? 96.253  106.766 112.343 1.00 43.89  ? 40  VAL A CG2  1 
ATOM   596  H H    . VAL A 1 40  ? 98.341  110.013 112.946 1.00 43.89  ? 40  VAL A H    1 
ATOM   597  H HA   . VAL A 1 40  ? 96.133  108.932 113.767 1.00 43.89  ? 40  VAL A HA   1 
ATOM   598  H HB   . VAL A 1 40  ? 97.220  108.433 111.679 1.00 43.89  ? 40  VAL A HB   1 
ATOM   599  H HG11 . VAL A 1 40  ? 99.280  107.826 113.003 1.00 43.89  ? 40  VAL A HG11 1 
ATOM   600  H HG12 . VAL A 1 40  ? 98.670  106.372 112.813 1.00 43.89  ? 40  VAL A HG12 1 
ATOM   601  H HG13 . VAL A 1 40  ? 99.034  107.256 111.543 1.00 43.89  ? 40  VAL A HG13 1 
ATOM   602  H HG21 . VAL A 1 40  ? 95.929  106.535 113.226 1.00 43.89  ? 40  VAL A HG21 1 
ATOM   603  H HG22 . VAL A 1 40  ? 95.520  107.090 111.797 1.00 43.89  ? 40  VAL A HG22 1 
ATOM   604  H HG23 . VAL A 1 40  ? 96.654  105.987 111.927 1.00 43.89  ? 40  VAL A HG23 1 
ATOM   605  N N    . PHE A 1 41  ? 96.442  107.270 115.568 1.00 43.85  ? 41  PHE A N    1 
ATOM   606  C CA   . PHE A 1 41  ? 96.497  106.606 116.870 1.00 43.85  ? 41  PHE A CA   1 
ATOM   607  C C    . PHE A 1 41  ? 96.494  107.598 118.025 1.00 43.85  ? 41  PHE A C    1 
ATOM   608  O O    . PHE A 1 41  ? 96.391  107.176 119.182 1.00 43.85  ? 41  PHE A O    1 
ATOM   609  C CB   . PHE A 1 41  ? 97.720  105.689 117.027 1.00 43.85  ? 41  PHE A CB   1 
ATOM   610  C CG   . PHE A 1 41  ? 97.723  104.506 116.103 1.00 43.85  ? 41  PHE A CG   1 
ATOM   611  C CD1  . PHE A 1 41  ? 96.550  103.846 115.787 1.00 43.85  ? 41  PHE A CD1  1 
ATOM   612  C CD2  . PHE A 1 41  ? 98.906  104.050 115.555 1.00 43.85  ? 41  PHE A CD2  1 
ATOM   613  C CE1  . PHE A 1 41  ? 96.559  102.758 114.942 1.00 43.85  ? 41  PHE A CE1  1 
ATOM   614  C CE2  . PHE A 1 41  ? 98.919  102.965 114.708 1.00 43.85  ? 41  PHE A CE2  1 
ATOM   615  C CZ   . PHE A 1 41  ? 97.744  102.319 114.401 1.00 43.85  ? 41  PHE A CZ   1 
ATOM   616  H H    . PHE A 1 41  ? 95.668  107.189 115.202 1.00 43.85  ? 41  PHE A H    1 
ATOM   617  H HA   . PHE A 1 41  ? 95.700  106.063 116.968 1.00 43.85  ? 41  PHE A HA   1 
ATOM   618  H HB2  . PHE A 1 41  ? 98.530  106.195 116.870 1.00 43.85  ? 41  PHE A HB2  1 
ATOM   619  H HB3  . PHE A 1 41  ? 97.727  105.345 117.934 1.00 43.85  ? 41  PHE A HB3  1 
ATOM   620  H HD1  . PHE A 1 41  ? 95.744  104.138 116.149 1.00 43.85  ? 41  PHE A HD1  1 
ATOM   621  H HD2  . PHE A 1 41  ? 99.703  104.484 115.758 1.00 43.85  ? 41  PHE A HD2  1 
ATOM   622  H HE1  . PHE A 1 41  ? 95.763  102.323 114.735 1.00 43.85  ? 41  PHE A HE1  1 
ATOM   623  H HE2  . PHE A 1 41  ? 99.721  102.668 114.344 1.00 43.85  ? 41  PHE A HE2  1 
ATOM   624  H HZ   . PHE A 1 41  ? 97.752  101.585 113.830 1.00 43.85  ? 41  PHE A HZ   1 
ATOM   625  N N    . LEU A 1 42  ? 96.595  108.899 117.754 1.00 45.77  ? 42  LEU A N    1 
ATOM   626  C CA   . LEU A 1 42  ? 96.529  109.920 118.786 1.00 45.77  ? 42  LEU A CA   1 
ATOM   627  C C    . LEU A 1 42  ? 95.498  110.998 118.498 1.00 45.77  ? 42  LEU A C    1 
ATOM   628  O O    . LEU A 1 42  ? 95.150  111.749 119.415 1.00 45.77  ? 42  LEU A O    1 
ATOM   629  C CB   . LEU A 1 42  ? 97.899  110.589 118.967 1.00 45.77  ? 42  LEU A CB   1 
ATOM   630  C CG   . LEU A 1 42  ? 98.988  109.711 119.577 1.00 45.77  ? 42  LEU A CG   1 
ATOM   631  C CD1  . LEU A 1 42  ? 100.357 110.314 119.336 1.00 45.77  ? 42  LEU A CD1  1 
ATOM   632  C CD2  . LEU A 1 42  ? 98.742  109.533 121.060 1.00 45.77  ? 42  LEU A CD2  1 
ATOM   633  H H    . LEU A 1 42  ? 96.703  109.220 116.965 1.00 45.77  ? 42  LEU A H    1 
ATOM   634  H HA   . LEU A 1 42  ? 96.289  109.504 119.628 1.00 45.77  ? 42  LEU A HA   1 
ATOM   635  H HB2  . LEU A 1 42  ? 98.214  110.881 118.098 1.00 45.77  ? 42  LEU A HB2  1 
ATOM   636  H HB3  . LEU A 1 42  ? 97.789  111.360 119.547 1.00 45.77  ? 42  LEU A HB3  1 
ATOM   637  H HG   . LEU A 1 42  ? 98.963  108.836 119.159 1.00 45.77  ? 42  LEU A HG   1 
ATOM   638  H HD11 . LEU A 1 42  ? 101.027 109.752 119.755 1.00 45.77  ? 42  LEU A HD11 1 
ATOM   639  H HD12 . LEU A 1 42  ? 100.517 110.362 118.380 1.00 45.77  ? 42  LEU A HD12 1 
ATOM   640  H HD13 . LEU A 1 42  ? 100.383 111.203 119.721 1.00 45.77  ? 42  LEU A HD13 1 
ATOM   641  H HD21 . LEU A 1 42  ? 99.435  108.962 121.427 1.00 45.77  ? 42  LEU A HD21 1 
ATOM   642  H HD22 . LEU A 1 42  ? 98.768  110.403 121.489 1.00 45.77  ? 42  LEU A HD22 1 
ATOM   643  H HD23 . LEU A 1 42  ? 97.873  109.125 121.191 1.00 45.77  ? 42  LEU A HD23 1 
ATOM   644  N N    . GLY A 1 43  ? 95.002  111.100 117.268 1.00 48.35  ? 43  GLY A N    1 
ATOM   645  C CA   . GLY A 1 43  ? 93.982  112.073 116.938 1.00 48.35  ? 43  GLY A CA   1 
ATOM   646  C C    . GLY A 1 43  ? 92.912  111.515 116.028 1.00 48.35  ? 43  GLY A C    1 
ATOM   647  O O    . GLY A 1 43  ? 92.319  112.249 115.233 1.00 48.35  ? 43  GLY A O    1 
ATOM   648  H H    . GLY A 1 43  ? 95.246  110.611 116.605 1.00 48.35  ? 43  GLY A H    1 
ATOM   649  H HA2  . GLY A 1 43  ? 93.546  112.366 117.750 1.00 48.35  ? 43  GLY A HA2  1 
ATOM   650  H HA3  . GLY A 1 43  ? 94.385  112.844 116.510 1.00 48.35  ? 43  GLY A HA3  1 
ATOM   651  N N    . PHE A 1 44  ? 92.655  110.216 116.131 1.00 51.64  ? 44  PHE A N    1 
ATOM   652  C CA   . PHE A 1 44  ? 91.600  109.608 115.336 1.00 51.64  ? 44  PHE A CA   1 
ATOM   653  C C    . PHE A 1 44  ? 90.251  110.149 115.789 1.00 51.64  ? 44  PHE A C    1 
ATOM   654  O O    . PHE A 1 44  ? 89.949  110.170 116.985 1.00 51.64  ? 44  PHE A O    1 
ATOM   655  C CB   . PHE A 1 44  ? 91.646  108.086 115.465 1.00 51.64  ? 44  PHE A CB   1 
ATOM   656  C CG   . PHE A 1 44  ? 91.246  107.575 116.818 1.00 51.64  ? 44  PHE A CG   1 
ATOM   657  C CD1  . PHE A 1 44  ? 92.167  107.489 117.843 1.00 51.64  ? 44  PHE A CD1  1 
ATOM   658  C CD2  . PHE A 1 44  ? 89.950  107.167 117.059 1.00 51.64  ? 44  PHE A CD2  1 
ATOM   659  C CE1  . PHE A 1 44  ? 91.798  107.011 119.082 1.00 51.64  ? 44  PHE A CE1  1 
ATOM   660  C CE2  . PHE A 1 44  ? 89.579  106.692 118.296 1.00 51.64  ? 44  PHE A CE2  1 
ATOM   661  C CZ   . PHE A 1 44  ? 90.503  106.615 119.308 1.00 51.64  ? 44  PHE A CZ   1 
ATOM   662  H H    . PHE A 1 44  ? 93.073  109.671 116.648 1.00 51.64  ? 44  PHE A H    1 
ATOM   663  H HA   . PHE A 1 44  ? 91.725  109.840 114.403 1.00 51.64  ? 44  PHE A HA   1 
ATOM   664  H HB2  . PHE A 1 44  ? 91.043  107.699 114.811 1.00 51.64  ? 44  PHE A HB2  1 
ATOM   665  H HB3  . PHE A 1 44  ? 92.552  107.787 115.292 1.00 51.64  ? 44  PHE A HB3  1 
ATOM   666  H HD1  . PHE A 1 44  ? 93.045  107.757 117.697 1.00 51.64  ? 44  PHE A HD1  1 
ATOM   667  H HD2  . PHE A 1 44  ? 89.319  107.217 116.378 1.00 51.64  ? 44  PHE A HD2  1 
ATOM   668  H HE1  . PHE A 1 44  ? 92.425  106.961 119.767 1.00 51.64  ? 44  PHE A HE1  1 
ATOM   669  H HE2  . PHE A 1 44  ? 88.701  106.423 118.444 1.00 51.64  ? 44  PHE A HE2  1 
ATOM   670  H HZ   . PHE A 1 44  ? 90.252  106.294 120.144 1.00 51.64  ? 44  PHE A HZ   1 
ATOM   671  N N    . THR A 1 45  ? 89.440  110.590 114.830 1.00 57.34  ? 45  THR A N    1 
ATOM   672  C CA   . THR A 1 45  ? 88.176  111.237 115.141 1.00 57.34  ? 45  THR A CA   1 
ATOM   673  C C    . THR A 1 45  ? 87.054  110.217 115.037 1.00 57.34  ? 45  THR A C    1 
ATOM   674  O O    . THR A 1 45  ? 86.726  109.788 113.921 1.00 57.34  ? 45  THR A O    1 
ATOM   675  C CB   . THR A 1 45  ? 87.925  112.404 114.188 1.00 57.34  ? 45  THR A CB   1 
ATOM   676  O OG1  . THR A 1 45  ? 89.074  113.258 114.163 1.00 57.34  ? 45  THR A OG1  1 
ATOM   677  C CG2  . THR A 1 45  ? 86.715  113.210 114.631 1.00 57.34  ? 45  THR A CG2  1 
ATOM   678  H H    . THR A 1 45  ? 89.602  110.525 113.988 1.00 57.34  ? 45  THR A H    1 
ATOM   679  H HA   . THR A 1 45  ? 88.211  111.594 116.041 1.00 57.34  ? 45  THR A HA   1 
ATOM   680  H HB   . THR A 1 45  ? 87.757  112.062 113.296 1.00 57.34  ? 45  THR A HB   1 
ATOM   681  H HG1  . THR A 1 45  ? 88.948  113.893 113.628 1.00 57.34  ? 45  THR A HG1  1 
ATOM   682  H HG21 . THR A 1 45  ? 86.613  113.990 114.064 1.00 57.34  ? 45  THR A HG21 1 
ATOM   683  H HG22 . THR A 1 45  ? 85.912  112.669 114.568 1.00 57.34  ? 45  THR A HG22 1 
ATOM   684  H HG23 . THR A 1 45  ? 86.828  113.501 115.549 1.00 57.34  ? 45  THR A HG23 1 
ATOM   685  N N    . PRO A 1 46  ? 86.442  109.801 116.136 1.00 58.46  ? 46  PRO A N    1 
ATOM   686  C CA   . PRO A 1 46  ? 85.344  108.836 116.065 1.00 58.46  ? 46  PRO A CA   1 
ATOM   687  C C    . PRO A 1 46  ? 84.019  109.533 115.775 1.00 58.46  ? 46  PRO A C    1 
ATOM   688  O O    . PRO A 1 46  ? 83.945  110.750 115.627 1.00 58.46  ? 46  PRO A O    1 
ATOM   689  C CB   . PRO A 1 46  ? 85.356  108.206 117.456 1.00 58.46  ? 46  PRO A CB   1 
ATOM   690  C CG   . PRO A 1 46  ? 85.829  109.302 118.337 1.00 58.46  ? 46  PRO A CG   1 
ATOM   691  C CD   . PRO A 1 46  ? 86.801  110.114 117.530 1.00 58.46  ? 46  PRO A CD   1 
ATOM   692  H HA   . PRO A 1 46  ? 85.518  108.158 115.393 1.00 58.46  ? 46  PRO A HA   1 
ATOM   693  H HB2  . PRO A 1 46  ? 84.461  107.926 117.701 1.00 58.46  ? 46  PRO A HB2  1 
ATOM   694  H HB3  . PRO A 1 46  ? 85.972  107.456 117.474 1.00 58.46  ? 46  PRO A HB3  1 
ATOM   695  H HG2  . PRO A 1 46  ? 85.073  109.847 118.606 1.00 58.46  ? 46  PRO A HG2  1 
ATOM   696  H HG3  . PRO A 1 46  ? 86.269  108.926 119.115 1.00 58.46  ? 46  PRO A HG3  1 
ATOM   697  H HD2  . PRO A 1 46  ? 86.679  111.060 117.706 1.00 58.46  ? 46  PRO A HD2  1 
ATOM   698  H HD3  . PRO A 1 46  ? 87.709  109.832 117.717 1.00 58.46  ? 46  PRO A HD3  1 
ATOM   699  N N    . ASP A 1 47  ? 82.961  108.730 115.697 1.00 68.64  ? 47  ASP A N    1 
ATOM   700  C CA   . ASP A 1 47  ? 81.625  109.278 115.522 1.00 68.64  ? 47  ASP A CA   1 
ATOM   701  C C    . ASP A 1 47  ? 81.247  110.117 116.736 1.00 68.64  ? 47  ASP A C    1 
ATOM   702  O O    . ASP A 1 47  ? 81.660  109.839 117.864 1.00 68.64  ? 47  ASP A O    1 
ATOM   703  C CB   . ASP A 1 47  ? 80.614  108.149 115.318 1.00 68.64  ? 47  ASP A CB   1 
ATOM   704  C CG   . ASP A 1 47  ? 79.235  108.657 114.945 1.00 68.64  ? 47  ASP A CG   1 
ATOM   705  O OD1  . ASP A 1 47  ? 78.762  109.629 115.570 1.00 68.64  ? 47  ASP A OD1  1 
ATOM   706  O OD2  . ASP A 1 47  ? 78.621  108.082 114.022 1.00 68.64  ? 47  ASP A OD2  1 
ATOM   707  H H    . ASP A 1 47  ? 82.992  107.872 115.743 1.00 68.64  ? 47  ASP A H    1 
ATOM   708  H HA   . ASP A 1 47  ? 81.610  109.848 114.738 1.00 68.64  ? 47  ASP A HA   1 
ATOM   709  H HB2  . ASP A 1 47  ? 80.925  107.572 114.603 1.00 68.64  ? 47  ASP A HB2  1 
ATOM   710  H HB3  . ASP A 1 47  ? 80.534  107.643 116.142 1.00 68.64  ? 47  ASP A HB3  1 
ATOM   711  N N    . HIS A 1 48  ? 80.450  111.156 116.501 1.00 72.99  ? 48  HIS A N    1 
ATOM   712  C CA   . HIS A 1 48  ? 80.122  112.096 117.562 1.00 72.99  ? 48  HIS A CA   1 
ATOM   713  C C    . HIS A 1 48  ? 78.795  112.771 117.259 1.00 72.99  ? 48  HIS A C    1 
ATOM   714  O O    . HIS A 1 48  ? 78.556  113.207 116.131 1.00 72.99  ? 48  HIS A O    1 
ATOM   715  C CB   . HIS A 1 48  ? 81.226  113.144 117.712 1.00 72.99  ? 48  HIS A CB   1 
ATOM   716  C CG   . HIS A 1 48  ? 81.712  113.691 116.409 1.00 72.99  ? 48  HIS A CG   1 
ATOM   717  N ND1  . HIS A 1 48  ? 80.930  114.482 115.596 1.00 72.99  ? 48  HIS A ND1  1 
ATOM   718  C CD2  . HIS A 1 48  ? 82.898  113.556 115.772 1.00 72.99  ? 48  HIS A CD2  1 
ATOM   719  C CE1  . HIS A 1 48  ? 81.615  114.815 114.517 1.00 72.99  ? 48  HIS A CE1  1 
ATOM   720  N NE2  . HIS A 1 48  ? 82.813  114.266 114.600 1.00 72.99  ? 48  HIS A NE2  1 
ATOM   721  H H    . HIS A 1 48  ? 80.091  111.337 115.741 1.00 72.99  ? 48  HIS A H    1 
ATOM   722  H HA   . HIS A 1 48  ? 80.037  111.618 118.401 1.00 72.99  ? 48  HIS A HA   1 
ATOM   723  H HB2  . HIS A 1 48  ? 80.884  113.885 118.236 1.00 72.99  ? 48  HIS A HB2  1 
ATOM   724  H HB3  . HIS A 1 48  ? 81.982  112.740 118.165 1.00 72.99  ? 48  HIS A HB3  1 
ATOM   725  H HD2  . HIS A 1 48  ? 83.635  113.076 116.074 1.00 72.99  ? 48  HIS A HD2  1 
ATOM   726  H HE1  . HIS A 1 48  ? 81.306  115.345 113.818 1.00 72.99  ? 48  HIS A HE1  1 
ATOM   727  H HE2  . HIS A 1 48  ? 83.439  114.340 114.014 1.00 72.99  ? 48  HIS A HE2  1 
ATOM   728  N N    . ARG A 1 49  ? 77.945  112.860 118.277 1.00 88.04  ? 49  ARG A N    1 
ATOM   729  C CA   . ARG A 1 49  ? 76.673  113.559 118.192 1.00 88.04  ? 49  ARG A CA   1 
ATOM   730  C C    . ARG A 1 49  ? 76.539  114.469 119.404 1.00 88.04  ? 49  ARG A C    1 
ATOM   731  O O    . ARG A 1 49  ? 77.285  114.353 120.379 1.00 88.04  ? 49  ARG A O    1 
ATOM   732  C CB   . ARG A 1 49  ? 75.496  112.579 118.120 1.00 88.04  ? 49  ARG A CB   1 
ATOM   733  C CG   . ARG A 1 49  ? 75.312  111.733 119.368 1.00 88.04  ? 49  ARG A CG   1 
ATOM   734  C CD   . ARG A 1 49  ? 74.149  110.771 119.212 1.00 88.04  ? 49  ARG A CD   1 
ATOM   735  N NE   . ARG A 1 49  ? 73.780  110.146 120.476 1.00 88.04  ? 49  ARG A NE   1 
ATOM   736  C CZ   . ARG A 1 49  ? 74.340  109.050 120.967 1.00 88.04  ? 49  ARG A CZ   1 
ATOM   737  N NH1  . ARG A 1 49  ? 75.310  108.420 120.325 1.00 88.04  ? 49  ARG A NH1  1 
ATOM   738  N NH2  . ARG A 1 49  ? 73.917  108.575 122.135 1.00 88.04  ? 49  ARG A NH2  1 
ATOM   739  H H    . ARG A 1 49  ? 78.089  112.510 119.049 1.00 88.04  ? 49  ARG A H    1 
ATOM   740  H HA   . ARG A 1 49  ? 76.659  114.110 117.394 1.00 88.04  ? 49  ARG A HA   1 
ATOM   741  H HB2  . ARG A 1 49  ? 74.679  113.084 117.981 1.00 88.04  ? 49  ARG A HB2  1 
ATOM   742  H HB3  . ARG A 1 49  ? 75.638  111.977 117.373 1.00 88.04  ? 49  ARG A HB3  1 
ATOM   743  H HG2  . ARG A 1 49  ? 76.117  111.216 119.529 1.00 88.04  ? 49  ARG A HG2  1 
ATOM   744  H HG3  . ARG A 1 49  ? 75.125  112.309 120.126 1.00 88.04  ? 49  ARG A HG3  1 
ATOM   745  H HD2  . ARG A 1 49  ? 73.380  111.265 118.889 1.00 88.04  ? 49  ARG A HD2  1 
ATOM   746  H HD3  . ARG A 1 49  ? 74.388  110.075 118.580 1.00 88.04  ? 49  ARG A HD3  1 
ATOM   747  H HE   . ARG A 1 49  ? 73.118  110.485 120.909 1.00 88.04  ? 49  ARG A HE   1 
ATOM   748  H HH11 . ARG A 1 49  ? 75.594  108.716 119.570 1.00 88.04  ? 49  ARG A HH11 1 
ATOM   749  H HH12 . ARG A 1 49  ? 75.658  107.711 120.665 1.00 88.04  ? 49  ARG A HH12 1 
ATOM   750  H HH21 . ARG A 1 49  ? 73.287  108.978 122.560 1.00 88.04  ? 49  ARG A HH21 1 
ATOM   751  H HH22 . ARG A 1 49  ? 74.273  107.865 122.465 1.00 88.04  ? 49  ARG A HH22 1 
ATOM   752  N N    . CYS A 1 50  ? 75.574  115.381 119.344 1.00 89.49  ? 50  CYS A N    1 
ATOM   753  C CA   . CYS A 1 50  ? 75.407  116.367 120.404 1.00 89.49  ? 50  CYS A CA   1 
ATOM   754  C C    . CYS A 1 50  ? 74.793  115.704 121.628 1.00 89.49  ? 50  CYS A C    1 
ATOM   755  O O    . CYS A 1 50  ? 73.710  115.116 121.549 1.00 89.49  ? 50  CYS A O    1 
ATOM   756  C CB   . CYS A 1 50  ? 74.541  117.530 119.926 1.00 89.49  ? 50  CYS A CB   1 
ATOM   757  S SG   . CYS A 1 50  ? 75.292  118.471 118.584 1.00 89.49  ? 50  CYS A SG   1 
ATOM   758  H H    . CYS A 1 50  ? 75.004  115.449 118.704 1.00 89.49  ? 50  CYS A H    1 
ATOM   759  H HA   . CYS A 1 50  ? 76.277  116.718 120.652 1.00 89.49  ? 50  CYS A HA   1 
ATOM   760  H HB2  . CYS A 1 50  ? 73.694  117.180 119.608 1.00 89.49  ? 50  CYS A HB2  1 
ATOM   761  H HB3  . CYS A 1 50  ? 74.391  118.135 120.668 1.00 89.49  ? 50  CYS A HB3  1 
ATOM   762  N N    . ARG A 1 51  ? 75.490  115.797 122.755 1.00 90.30  ? 51  ARG A N    1 
ATOM   763  C CA   . ARG A 1 51  ? 74.963  115.289 124.011 1.00 90.30  ? 51  ARG A CA   1 
ATOM   764  C C    . ARG A 1 51  ? 73.706  116.054 124.396 1.00 90.30  ? 51  ARG A C    1 
ATOM   765  O O    . ARG A 1 51  ? 73.631  117.276 124.240 1.00 90.30  ? 51  ARG A O    1 
ATOM   766  C CB   . ARG A 1 51  ? 76.018  115.420 125.111 1.00 90.30  ? 51  ARG A CB   1 
ATOM   767  C CG   . ARG A 1 51  ? 75.523  115.132 126.524 1.00 90.30  ? 51  ARG A CG   1 
ATOM   768  C CD   . ARG A 1 51  ? 75.276  113.655 126.749 1.00 90.30  ? 51  ARG A CD   1 
ATOM   769  N NE   . ARG A 1 51  ? 76.523  112.905 126.823 1.00 90.30  ? 51  ARG A NE   1 
ATOM   770  C CZ   . ARG A 1 51  ? 77.341  112.911 127.867 1.00 90.30  ? 51  ARG A CZ   1 
ATOM   771  N NH1  . ARG A 1 51  ? 77.085  113.640 128.942 1.00 90.30  ? 51  ARG A NH1  1 
ATOM   772  N NH2  . ARG A 1 51  ? 78.445  112.171 127.832 1.00 90.30  ? 51  ARG A NH2  1 
ATOM   773  H H    . ARG A 1 51  ? 76.272  116.151 122.817 1.00 90.30  ? 51  ARG A H    1 
ATOM   774  H HA   . ARG A 1 51  ? 74.736  114.351 123.911 1.00 90.30  ? 51  ARG A HA   1 
ATOM   775  H HB2  . ARG A 1 51  ? 76.739  114.798 124.922 1.00 90.30  ? 51  ARG A HB2  1 
ATOM   776  H HB3  . ARG A 1 51  ? 76.361  116.326 125.099 1.00 90.30  ? 51  ARG A HB3  1 
ATOM   777  H HG2  . ARG A 1 51  ? 76.203  115.417 127.154 1.00 90.30  ? 51  ARG A HG2  1 
ATOM   778  H HG3  . ARG A 1 51  ? 74.698  115.610 126.697 1.00 90.30  ? 51  ARG A HG3  1 
ATOM   779  H HD2  . ARG A 1 51  ? 74.798  113.534 127.584 1.00 90.30  ? 51  ARG A HD2  1 
ATOM   780  H HD3  . ARG A 1 51  ? 74.754  113.303 126.011 1.00 90.30  ? 51  ARG A HD3  1 
ATOM   781  H HE   . ARG A 1 51  ? 76.756  112.444 126.135 1.00 90.30  ? 51  ARG A HE   1 
ATOM   782  H HH11 . ARG A 1 51  ? 76.375  114.123 128.977 1.00 90.30  ? 51  ARG A HH11 1 
ATOM   783  H HH12 . ARG A 1 51  ? 77.630  113.629 129.607 1.00 90.30  ? 51  ARG A HH12 1 
ATOM   784  H HH21 . ARG A 1 51  ? 78.620  111.694 127.138 1.00 90.30  ? 51  ARG A HH21 1 
ATOM   785  H HH22 . ARG A 1 51  ? 78.983  112.168 128.502 1.00 90.30  ? 51  ARG A HH22 1 
ATOM   786  N N    . SER A 1 52  ? 72.709  115.327 124.895 1.00 103.20 ? 52  SER A N    1 
ATOM   787  C CA   . SER A 1 52  ? 71.498  115.941 125.409 1.00 103.20 ? 52  SER A CA   1 
ATOM   788  C C    . SER A 1 52  ? 71.181  115.364 126.781 1.00 103.20 ? 52  SER A C    1 
ATOM   789  O O    . SER A 1 52  ? 71.306  114.150 126.984 1.00 103.20 ? 52  SER A O    1 
ATOM   790  C CB   . SER A 1 52  ? 70.314  115.711 124.463 1.00 103.20 ? 52  SER A CB   1 
ATOM   791  O OG   . SER A 1 52  ? 69.134  116.299 124.982 1.00 103.20 ? 52  SER A OG   1 
ATOM   792  H H    . SER A 1 52  ? 72.715  114.468 124.946 1.00 103.20 ? 52  SER A H    1 
ATOM   793  H HA   . SER A 1 52  ? 71.641  116.894 125.480 1.00 103.20 ? 52  SER A HA   1 
ATOM   794  H HB2  . SER A 1 52  ? 70.514  116.114 123.603 1.00 103.20 ? 52  SER A HB2  1 
ATOM   795  H HB3  . SER A 1 52  ? 70.173  114.757 124.358 1.00 103.20 ? 52  SER A HB3  1 
ATOM   796  H HG   . SER A 1 52  ? 69.250  117.123 125.096 1.00 103.20 ? 52  SER A HG   1 
ATOM   797  N N    . PRO A 1 53  ? 70.772  116.196 127.745 1.00 109.09 ? 53  PRO A N    1 
ATOM   798  C CA   . PRO A 1 53  ? 70.456  115.639 129.072 1.00 109.09 ? 53  PRO A CA   1 
ATOM   799  C C    . PRO A 1 53  ? 69.188  114.806 129.085 1.00 109.09 ? 53  PRO A C    1 
ATOM   800  O O    . PRO A 1 53  ? 69.116  113.809 129.815 1.00 109.09 ? 53  PRO A O    1 
ATOM   801  C CB   . PRO A 1 53  ? 70.324  116.888 129.959 1.00 109.09 ? 53  PRO A CB   1 
ATOM   802  C CG   . PRO A 1 53  ? 70.943  118.004 129.181 1.00 109.09 ? 53  PRO A CG   1 
ATOM   803  C CD   . PRO A 1 53  ? 70.721  117.667 127.747 1.00 109.09 ? 53  PRO A CD   1 
ATOM   804  H HA   . PRO A 1 53  ? 71.195  115.098 129.392 1.00 109.09 ? 53  PRO A HA   1 
ATOM   805  H HB2  . PRO A 1 53  ? 69.387  117.070 130.130 1.00 109.09 ? 53  PRO A HB2  1 
ATOM   806  H HB3  . PRO A 1 53  ? 70.802  116.747 130.791 1.00 109.09 ? 53  PRO A HB3  1 
ATOM   807  H HG2  . PRO A 1 53  ? 70.508  118.840 129.408 1.00 109.09 ? 53  PRO A HG2  1 
ATOM   808  H HG3  . PRO A 1 53  ? 71.892  118.048 129.377 1.00 109.09 ? 53  PRO A HG3  1 
ATOM   809  H HD2  . PRO A 1 53  ? 69.849  117.979 127.457 1.00 109.09 ? 53  PRO A HD2  1 
ATOM   810  H HD3  . PRO A 1 53  ? 71.434  118.044 127.210 1.00 109.09 ? 53  PRO A HD3  1 
ATOM   811  N N    . GLY A 1 54  ? 68.181  115.184 128.295 1.00 118.44 ? 54  GLY A N    1 
ATOM   812  C CA   . GLY A 1 54  ? 66.903  114.496 128.356 1.00 118.44 ? 54  GLY A CA   1 
ATOM   813  C C    . GLY A 1 54  ? 66.956  113.066 127.856 1.00 118.44 ? 54  GLY A C    1 
ATOM   814  O O    . GLY A 1 54  ? 66.188  112.216 128.317 1.00 118.44 ? 54  GLY A O    1 
ATOM   815  H H    . GLY A 1 54  ? 68.216  115.827 127.725 1.00 118.44 ? 54  GLY A H    1 
ATOM   816  H HA2  . GLY A 1 54  ? 66.590  114.486 129.274 1.00 118.44 ? 54  GLY A HA2  1 
ATOM   817  H HA3  . GLY A 1 54  ? 66.257  114.983 127.822 1.00 118.44 ? 54  GLY A HA3  1 
ATOM   818  N N    . VAL A 1 55  ? 67.857  112.777 126.915 1.00 120.43 ? 55  VAL A N    1 
ATOM   819  C CA   . VAL A 1 55  ? 67.921  111.438 126.334 1.00 120.43 ? 55  VAL A CA   1 
ATOM   820  C C    . VAL A 1 55  ? 68.327  110.416 127.387 1.00 120.43 ? 55  VAL A C    1 
ATOM   821  O O    . VAL A 1 55  ? 67.887  109.261 127.356 1.00 120.43 ? 55  VAL A O    1 
ATOM   822  C CB   . VAL A 1 55  ? 68.880  111.425 125.129 1.00 120.43 ? 55  VAL A CB   1 
ATOM   823  C CG1  . VAL A 1 55  ? 69.039  110.013 124.585 1.00 120.43 ? 55  VAL A CG1  1 
ATOM   824  C CG2  . VAL A 1 55  ? 68.372  112.360 124.045 1.00 120.43 ? 55  VAL A CG2  1 
ATOM   825  H H    . VAL A 1 55  ? 68.434  113.331 126.601 1.00 120.43 ? 55  VAL A H    1 
ATOM   826  H HA   . VAL A 1 55  ? 67.038  111.194 126.013 1.00 120.43 ? 55  VAL A HA   1 
ATOM   827  H HB   . VAL A 1 55  ? 69.752  111.739 125.415 1.00 120.43 ? 55  VAL A HB   1 
ATOM   828  H HG11 . VAL A 1 55  ? 69.454  110.062 123.709 1.00 120.43 ? 55  VAL A HG11 1 
ATOM   829  H HG12 . VAL A 1 55  ? 69.600  109.499 125.186 1.00 120.43 ? 55  VAL A HG12 1 
ATOM   830  H HG13 . VAL A 1 55  ? 68.163  109.603 124.511 1.00 120.43 ? 55  VAL A HG13 1 
ATOM   831  H HG21 . VAL A 1 55  ? 68.982  112.331 123.292 1.00 120.43 ? 55  VAL A HG21 1 
ATOM   832  H HG22 . VAL A 1 55  ? 67.489  112.070 123.768 1.00 120.43 ? 55  VAL A HG22 1 
ATOM   833  H HG23 . VAL A 1 55  ? 68.328  113.262 124.401 1.00 120.43 ? 55  VAL A HG23 1 
ATOM   834  N N    . ALA A 1 56  ? 69.181  110.820 128.330 1.00 121.55 ? 56  ALA A N    1 
ATOM   835  C CA   . ALA A 1 56  ? 69.640  109.886 129.352 1.00 121.55 ? 56  ALA A CA   1 
ATOM   836  C C    . ALA A 1 56  ? 68.470  109.323 130.151 1.00 121.55 ? 56  ALA A C    1 
ATOM   837  O O    . ALA A 1 56  ? 68.455  108.134 130.491 1.00 121.55 ? 56  ALA A O    1 
ATOM   838  C CB   . ALA A 1 56  ? 70.645  110.579 130.273 1.00 121.55 ? 56  ALA A CB   1 
ATOM   839  H H    . ALA A 1 56  ? 69.503  111.615 128.398 1.00 121.55 ? 56  ALA A H    1 
ATOM   840  H HA   . ALA A 1 56  ? 70.093  109.145 128.921 1.00 121.55 ? 56  ALA A HA   1 
ATOM   841  H HB1  . ALA A 1 56  ? 70.944  109.953 130.950 1.00 121.55 ? 56  ALA A HB1  1 
ATOM   842  H HB2  . ALA A 1 56  ? 71.402  110.875 129.742 1.00 121.55 ? 56  ALA A HB2  1 
ATOM   843  H HB3  . ALA A 1 56  ? 70.219  111.343 130.692 1.00 121.55 ? 56  ALA A HB3  1 
ATOM   844  N N    . GLU A 1 57  ? 67.476  110.161 130.459 1.00 125.83 ? 57  GLU A N    1 
ATOM   845  C CA   . GLU A 1 57  ? 66.306  109.691 131.197 1.00 125.83 ? 57  GLU A CA   1 
ATOM   846  C C    . GLU A 1 57  ? 65.512  108.670 130.388 1.00 125.83 ? 57  GLU A C    1 
ATOM   847  O O    . GLU A 1 57  ? 65.158  107.599 130.894 1.00 125.83 ? 57  GLU A O    1 
ATOM   848  C CB   . GLU A 1 57  ? 65.425  110.881 131.578 1.00 125.83 ? 57  GLU A CB   1 
ATOM   849  H H    . GLU A 1 57  ? 67.461  110.996 130.260 1.00 125.83 ? 57  GLU A H    1 
ATOM   850  H HA   . GLU A 1 57  ? 66.594  109.262 132.018 1.00 125.83 ? 57  GLU A HA   1 
ATOM   851  N N    . LEU A 1 58  ? 65.225  108.985 129.123 1.00 127.30 ? 58  LEU A N    1 
ATOM   852  C CA   . LEU A 1 58  ? 64.402  108.100 128.304 1.00 127.30 ? 58  LEU A CA   1 
ATOM   853  C C    . LEU A 1 58  ? 65.124  106.793 127.997 1.00 127.30 ? 58  LEU A C    1 
ATOM   854  O O    . LEU A 1 58  ? 64.482  105.753 127.808 1.00 127.30 ? 58  LEU A O    1 
ATOM   855  C CB   . LEU A 1 58  ? 64.002  108.813 127.009 1.00 127.30 ? 58  LEU A CB   1 
ATOM   856  C CG   . LEU A 1 58  ? 63.314  107.952 125.947 1.00 127.30 ? 58  LEU A CG   1 
ATOM   857  C CD1  . LEU A 1 58  ? 62.030  107.361 126.502 1.00 127.30 ? 58  LEU A CD1  1 
ATOM   858  C CD2  . LEU A 1 58  ? 63.049  108.763 124.685 1.00 127.30 ? 58  LEU A CD2  1 
ATOM   859  H H    . LEU A 1 58  ? 65.493  109.693 128.716 1.00 127.30 ? 58  LEU A H    1 
ATOM   860  H HA   . LEU A 1 58  ? 63.589  107.895 128.792 1.00 127.30 ? 58  LEU A HA   1 
ATOM   861  H HB2  . LEU A 1 58  ? 63.390  109.532 127.236 1.00 127.30 ? 58  LEU A HB2  1 
ATOM   862  H HB3  . LEU A 1 58  ? 64.798  109.189 126.605 1.00 127.30 ? 58  LEU A HB3  1 
ATOM   863  H HG   . LEU A 1 58  ? 63.896  107.217 125.702 1.00 127.30 ? 58  LEU A HG   1 
ATOM   864  H HD11 . LEU A 1 58  ? 61.543  106.927 125.784 1.00 127.30 ? 58  LEU A HD11 1 
ATOM   865  H HD12 . LEU A 1 58  ? 62.254  106.711 127.185 1.00 127.30 ? 58  LEU A HD12 1 
ATOM   866  H HD13 . LEU A 1 58  ? 61.497  108.074 126.888 1.00 127.30 ? 58  LEU A HD13 1 
ATOM   867  H HD21 . LEU A 1 58  ? 62.619  108.195 124.026 1.00 127.30 ? 58  LEU A HD21 1 
ATOM   868  H HD22 . LEU A 1 58  ? 62.473  109.511 124.904 1.00 127.30 ? 58  LEU A HD22 1 
ATOM   869  H HD23 . LEU A 1 58  ? 63.895  109.089 124.337 1.00 127.30 ? 58  LEU A HD23 1 
ATOM   870  N N    . SER A 1 59  ? 66.456  106.829 127.939 1.00 125.95 ? 59  SER A N    1 
ATOM   871  C CA   . SER A 1 59  ? 67.209  105.663 127.490 1.00 125.95 ? 59  SER A CA   1 
ATOM   872  C C    . SER A 1 59  ? 66.899  104.423 128.320 1.00 125.95 ? 59  SER A C    1 
ATOM   873  O O    . SER A 1 59  ? 66.937  103.303 127.798 1.00 125.95 ? 59  SER A O    1 
ATOM   874  C CB   . SER A 1 59  ? 68.706  105.957 127.539 1.00 125.95 ? 59  SER A CB   1 
ATOM   875  O OG   . SER A 1 59  ? 69.446  104.904 126.947 1.00 125.95 ? 59  SER A OG   1 
ATOM   876  H H    . SER A 1 59  ? 66.940  107.507 128.153 1.00 125.95 ? 59  SER A H    1 
ATOM   877  H HA   . SER A 1 59  ? 66.973  105.478 126.569 1.00 125.95 ? 59  SER A HA   1 
ATOM   878  H HB2  . SER A 1 59  ? 68.886  106.784 127.065 1.00 125.95 ? 59  SER A HB2  1 
ATOM   879  H HB3  . SER A 1 59  ? 68.969  106.041 128.469 1.00 125.95 ? 59  SER A HB3  1 
ATOM   880  H HG   . SER A 1 59  ? 69.527  104.267 127.488 1.00 125.95 ? 59  SER A HG   1 
ATOM   881  N N    . GLN A 1 60  ? 66.616  104.594 129.611 1.00 130.03 ? 60  GLN A N    1 
ATOM   882  C CA   . GLN A 1 60  ? 66.343  103.457 130.480 1.00 130.03 ? 60  GLN A CA   1 
ATOM   883  C C    . GLN A 1 60  ? 64.867  103.083 130.527 1.00 130.03 ? 60  GLN A C    1 
ATOM   884  O O    . GLN A 1 60  ? 64.545  101.938 130.862 1.00 130.03 ? 60  GLN A O    1 
ATOM   885  C CB   . GLN A 1 60  ? 66.835  103.756 131.897 1.00 130.03 ? 60  GLN A CB   1 
ATOM   886  H H    . GLN A 1 60  ? 66.576  105.357 130.005 1.00 130.03 ? 60  GLN A H    1 
ATOM   887  H HA   . GLN A 1 60  ? 66.833  102.684 130.157 1.00 130.03 ? 60  GLN A HA   1 
ATOM   888  N N    . ARG A 1 61  ? 63.967  104.014 130.201 1.00 130.15 ? 61  ARG A N    1 
ATOM   889  C CA   . ARG A 1 61  ? 62.544  103.760 130.404 1.00 130.15 ? 61  ARG A CA   1 
ATOM   890  C C    . ARG A 1 61  ? 62.058  102.600 129.544 1.00 130.15 ? 61  ARG A C    1 
ATOM   891  O O    . ARG A 1 61  ? 61.317  101.733 130.022 1.00 130.15 ? 61  ARG A O    1 
ATOM   892  C CB   . ARG A 1 61  ? 61.738  105.023 130.104 1.00 130.15 ? 61  ARG A CB   1 
ATOM   893  C CG   . ARG A 1 61  ? 62.161  106.220 130.931 1.00 130.15 ? 61  ARG A CG   1 
ATOM   894  C CD   . ARG A 1 61  ? 61.060  107.264 131.036 1.00 130.15 ? 61  ARG A CD   1 
ATOM   895  N NE   . ARG A 1 61  ? 60.315  107.435 129.793 1.00 130.15 ? 61  ARG A NE   1 
ATOM   896  C CZ   . ARG A 1 61  ? 59.114  106.923 129.551 1.00 130.15 ? 61  ARG A CZ   1 
ATOM   897  N NH1  . ARG A 1 61  ? 58.483  106.177 130.445 1.00 130.15 ? 61  ARG A NH1  1 
ATOM   898  N NH2  . ARG A 1 61  ? 58.526  107.172 128.383 1.00 130.15 ? 61  ARG A NH2  1 
ATOM   899  H H    . ARG A 1 61  ? 64.150  104.784 129.867 1.00 130.15 ? 61  ARG A H    1 
ATOM   900  H HA   . ARG A 1 61  ? 62.403  103.525 131.333 1.00 130.15 ? 61  ARG A HA   1 
ATOM   901  H HB2  . ARG A 1 61  ? 61.850  105.257 129.170 1.00 130.15 ? 61  ARG A HB2  1 
ATOM   902  H HB3  . ARG A 1 61  ? 60.803  104.845 130.291 1.00 130.15 ? 61  ARG A HB3  1 
ATOM   903  H HG2  . ARG A 1 61  ? 62.380  105.921 131.827 1.00 130.15 ? 61  ARG A HG2  1 
ATOM   904  H HG3  . ARG A 1 61  ? 62.936  106.634 130.521 1.00 130.15 ? 61  ARG A HG3  1 
ATOM   905  H HD2  . ARG A 1 61  ? 60.447  107.010 131.741 1.00 130.15 ? 61  ARG A HD2  1 
ATOM   906  H HD3  . ARG A 1 61  ? 61.465  108.117 131.254 1.00 130.15 ? 61  ARG A HD3  1 
ATOM   907  H HE   . ARG A 1 61  ? 60.634  107.991 129.218 1.00 130.15 ? 61  ARG A HE   1 
ATOM   908  H HH11 . ARG A 1 61  ? 58.842  106.004 131.205 1.00 130.15 ? 61  ARG A HH11 1 
ATOM   909  H HH12 . ARG A 1 61  ? 57.705  105.861 130.260 1.00 130.15 ? 61  ARG A HH12 1 
ATOM   910  H HH21 . ARG A 1 61  ? 58.927  107.656 127.797 1.00 130.15 ? 61  ARG A HH21 1 
ATOM   911  H HH22 . ARG A 1 61  ? 57.747  106.847 128.214 1.00 130.15 ? 61  ARG A HH22 1 
ATOM   912  N N    . CYS A 1 62  ? 62.470  102.557 128.281 1.00 130.87 ? 62  CYS A N    1 
ATOM   913  C CA   . CYS A 1 62  ? 62.017  101.538 127.346 1.00 130.87 ? 62  CYS A CA   1 
ATOM   914  C C    . CYS A 1 62  ? 63.208  100.854 126.690 1.00 130.87 ? 62  CYS A C    1 
ATOM   915  O O    . CYS A 1 62  ? 64.338  101.348 126.736 1.00 130.87 ? 62  CYS A O    1 
ATOM   916  C CB   . CYS A 1 62  ? 61.102  102.130 126.270 1.00 130.87 ? 62  CYS A CB   1 
ATOM   917  S SG   . CYS A 1 62  ? 61.686  103.670 125.515 1.00 130.87 ? 62  CYS A SG   1 
ATOM   918  H H    . CYS A 1 62  ? 63.033  103.117 127.946 1.00 130.87 ? 62  CYS A H    1 
ATOM   919  H HA   . CYS A 1 62  ? 61.526  100.854 127.827 1.00 130.87 ? 62  CYS A HA   1 
ATOM   920  H HB2  . CYS A 1 62  ? 60.981  101.476 125.562 1.00 130.87 ? 62  CYS A HB2  1 
ATOM   921  H HB3  . CYS A 1 62  ? 60.248  102.325 126.685 1.00 130.87 ? 62  CYS A HB3  1 
ATOM   922  N N    . GLY A 1 63  ? 62.943  99.695  126.089 1.00 126.56 ? 63  GLY A N    1 
ATOM   923  C CA   . GLY A 1 63  ? 63.976  98.973  125.370 1.00 126.56 ? 63  GLY A CA   1 
ATOM   924  C C    . GLY A 1 63  ? 64.648  99.844  124.329 1.00 126.56 ? 63  GLY A C    1 
ATOM   925  O O    . GLY A 1 63  ? 63.971  100.528 123.557 1.00 126.56 ? 63  GLY A O    1 
ATOM   926  H H    . GLY A 1 63  ? 62.171  99.309  126.085 1.00 126.56 ? 63  GLY A H    1 
ATOM   927  H HA2  . GLY A 1 63  ? 64.650  98.652  125.988 1.00 126.56 ? 63  GLY A HA2  1 
ATOM   928  H HA3  . GLY A 1 63  ? 63.583  98.208  124.921 1.00 126.56 ? 63  GLY A HA3  1 
ATOM   929  N N    . TRP A 1 64  ? 65.980  99.834  124.302 1.00 125.57 ? 64  TRP A N    1 
ATOM   930  C CA   . TRP A 1 64  ? 66.750  100.659 123.383 1.00 125.57 ? 64  TRP A CA   1 
ATOM   931  C C    . TRP A 1 64  ? 67.893  99.853  122.782 1.00 125.57 ? 64  TRP A C    1 
ATOM   932  O O    . TRP A 1 64  ? 68.350  98.856  123.346 1.00 125.57 ? 64  TRP A O    1 
ATOM   933  C CB   . TRP A 1 64  ? 67.327  101.898 124.082 1.00 125.57 ? 64  TRP A CB   1 
ATOM   934  C CG   . TRP A 1 64  ? 66.417  103.095 124.104 1.00 125.57 ? 64  TRP A CG   1 
ATOM   935  C CD1  . TRP A 1 64  ? 65.704  103.564 125.167 1.00 125.57 ? 64  TRP A CD1  1 
ATOM   936  C CD2  . TRP A 1 64  ? 66.140  103.985 123.015 1.00 125.57 ? 64  TRP A CD2  1 
ATOM   937  N NE1  . TRP A 1 64  ? 65.000  104.687 124.809 1.00 125.57 ? 64  TRP A NE1  1 
ATOM   938  C CE2  . TRP A 1 64  ? 65.249  104.965 123.492 1.00 125.57 ? 64  TRP A CE2  1 
ATOM   939  C CE3  . TRP A 1 64  ? 66.557  104.045 121.683 1.00 125.57 ? 64  TRP A CE3  1 
ATOM   940  C CZ2  . TRP A 1 64  ? 64.767  105.992 122.686 1.00 125.57 ? 64  TRP A CZ2  1 
ATOM   941  C CZ3  . TRP A 1 64  ? 66.074  105.063 120.885 1.00 125.57 ? 64  TRP A CZ3  1 
ATOM   942  C CH2  . TRP A 1 64  ? 65.193  106.025 121.389 1.00 125.57 ? 64  TRP A CH2  1 
ATOM   943  H H    . TRP A 1 64  ? 66.467  99.350  124.820 1.00 125.57 ? 64  TRP A H    1 
ATOM   944  H HA   . TRP A 1 64  ? 66.184  100.958 122.654 1.00 125.57 ? 64  TRP A HA   1 
ATOM   945  H HB2  . TRP A 1 64  ? 67.546  101.662 124.998 1.00 125.57 ? 64  TRP A HB2  1 
ATOM   946  H HB3  . TRP A 1 64  ? 68.135  102.161 123.616 1.00 125.57 ? 64  TRP A HB3  1 
ATOM   947  H HD1  . TRP A 1 64  ? 65.697  103.184 126.014 1.00 125.57 ? 64  TRP A HD1  1 
ATOM   948  H HE1  . TRP A 1 64  ? 64.485  105.141 125.327 1.00 125.57 ? 64  TRP A HE1  1 
ATOM   949  H HE3  . TRP A 1 64  ? 67.145  103.411 121.340 1.00 125.57 ? 64  TRP A HE3  1 
ATOM   950  H HZ2  . TRP A 1 64  ? 64.179  106.631 123.018 1.00 125.57 ? 64  TRP A HZ2  1 
ATOM   951  H HZ3  . TRP A 1 64  ? 66.345  105.114 119.997 1.00 125.57 ? 64  TRP A HZ3  1 
ATOM   952  H HH2  . TRP A 1 64  ? 64.886  106.699 120.826 1.00 125.57 ? 64  TRP A HH2  1 
ATOM   953  N N    . SER A 1 65  ? 68.355  100.317 121.623 1.00 121.95 ? 65  SER A N    1 
ATOM   954  C CA   . SER A 1 65  ? 69.546  99.796  120.969 1.00 121.95 ? 65  SER A CA   1 
ATOM   955  C C    . SER A 1 65  ? 70.370  100.969 120.462 1.00 121.95 ? 65  SER A C    1 
ATOM   956  O O    . SER A 1 65  ? 69.825  102.026 120.132 1.00 121.95 ? 65  SER A O    1 
ATOM   957  C CB   . SER A 1 65  ? 69.189  98.856  119.810 1.00 121.95 ? 65  SER A CB   1 
ATOM   958  O OG   . SER A 1 65  ? 68.379  97.784  120.260 1.00 121.95 ? 65  SER A OG   1 
ATOM   959  H H    . SER A 1 65  ? 67.981  100.959 121.187 1.00 121.95 ? 65  SER A H    1 
ATOM   960  H HA   . SER A 1 65  ? 70.085  99.308  121.608 1.00 121.95 ? 65  SER A HA   1 
ATOM   961  H HB2  . SER A 1 65  ? 68.707  99.357  119.132 1.00 121.95 ? 65  SER A HB2  1 
ATOM   962  H HB3  . SER A 1 65  ? 70.007  98.492  119.436 1.00 121.95 ? 65  SER A HB3  1 
ATOM   963  H HG   . SER A 1 65  ? 68.270  97.226  119.642 1.00 121.95 ? 65  SER A HG   1 
ATOM   964  N N    . LEU A 1 66  ? 71.691  100.778 120.396 1.00 117.39 ? 66  LEU A N    1 
ATOM   965  C CA   . LEU A 1 66  ? 72.562  101.880 119.999 1.00 117.39 ? 66  LEU A CA   1 
ATOM   966  C C    . LEU A 1 66  ? 72.216  102.369 118.599 1.00 117.39 ? 66  LEU A C    1 
ATOM   967  O O    . LEU A 1 66  ? 72.149  103.580 118.357 1.00 117.39 ? 66  LEU A O    1 
ATOM   968  C CB   . LEU A 1 66  ? 74.031  101.457 120.074 1.00 117.39 ? 66  LEU A CB   1 
ATOM   969  C CG   . LEU A 1 66  ? 75.061  102.554 119.767 1.00 117.39 ? 66  LEU A CG   1 
ATOM   970  C CD1  . LEU A 1 66  ? 76.254  102.442 120.702 1.00 117.39 ? 66  LEU A CD1  1 
ATOM   971  C CD2  . LEU A 1 66  ? 75.528  102.494 118.319 1.00 117.39 ? 66  LEU A CD2  1 
ATOM   972  H H    . LEU A 1 66  ? 72.099  100.039 120.571 1.00 117.39 ? 66  LEU A H    1 
ATOM   973  H HA   . LEU A 1 66  ? 72.433  102.622 120.612 1.00 117.39 ? 66  LEU A HA   1 
ATOM   974  H HB2  . LEU A 1 66  ? 74.211  101.138 120.972 1.00 117.39 ? 66  LEU A HB2  1 
ATOM   975  H HB3  . LEU A 1 66  ? 74.178  100.736 119.443 1.00 117.39 ? 66  LEU A HB3  1 
ATOM   976  H HG   . LEU A 1 66  ? 74.653  103.421 119.911 1.00 117.39 ? 66  LEU A HG   1 
ATOM   977  H HD11 . LEU A 1 66  ? 76.908  103.117 120.464 1.00 117.39 ? 66  LEU A HD11 1 
ATOM   978  H HD12 . LEU A 1 66  ? 75.954  102.579 121.614 1.00 117.39 ? 66  LEU A HD12 1 
ATOM   979  H HD13 . LEU A 1 66  ? 76.645  101.559 120.610 1.00 117.39 ? 66  LEU A HD13 1 
ATOM   980  H HD21 . LEU A 1 66  ? 76.181  103.197 118.171 1.00 117.39 ? 66  LEU A HD21 1 
ATOM   981  H HD22 . LEU A 1 66  ? 75.937  101.630 118.158 1.00 117.39 ? 66  LEU A HD22 1 
ATOM   982  H HD23 . LEU A 1 66  ? 74.768  102.619 117.731 1.00 117.39 ? 66  LEU A HD23 1 
ATOM   983  N N    . ALA A 1 67  ? 71.984  101.445 117.664 1.00 118.44 ? 67  ALA A N    1 
ATOM   984  C CA   . ALA A 1 67  ? 71.592  101.849 116.317 1.00 118.44 ? 67  ALA A CA   1 
ATOM   985  C C    . ALA A 1 67  ? 70.268  102.599 116.335 1.00 118.44 ? 67  ALA A C    1 
ATOM   986  O O    . ALA A 1 67  ? 70.111  103.615 115.649 1.00 118.44 ? 67  ALA A O    1 
ATOM   987  C CB   . ALA A 1 67  ? 71.496  100.628 115.403 1.00 118.44 ? 67  ALA A CB   1 
ATOM   988  H H    . ALA A 1 67  ? 72.048  100.595 117.780 1.00 118.44 ? 67  ALA A H    1 
ATOM   989  H HA   . ALA A 1 67  ? 72.271  102.439 115.955 1.00 118.44 ? 67  ALA A HA   1 
ATOM   990  H HB1  . ALA A 1 67  ? 71.218  100.922 114.522 1.00 118.44 ? 67  ALA A HB1  1 
ATOM   991  H HB2  . ALA A 1 67  ? 72.363  100.196 115.350 1.00 118.44 ? 67  ALA A HB2  1 
ATOM   992  H HB3  . ALA A 1 67  ? 70.838  100.013 115.764 1.00 118.44 ? 67  ALA A HB3  1 
ATOM   993  N N    . GLU A 1 68  ? 69.303  102.112 117.117 1.00 120.49 ? 68  GLU A N    1 
ATOM   994  C CA   . GLU A 1 68  ? 67.994  102.754 117.166 1.00 120.49 ? 68  GLU A CA   1 
ATOM   995  C C    . GLU A 1 68  ? 68.091  104.175 117.707 1.00 120.49 ? 68  GLU A C    1 
ATOM   996  O O    . GLU A 1 68  ? 67.457  105.094 117.175 1.00 120.49 ? 68  GLU A O    1 
ATOM   997  C CB   . GLU A 1 68  ? 67.040  101.923 118.023 1.00 120.49 ? 68  GLU A CB   1 
ATOM   998  C CG   . GLU A 1 68  ? 66.556  100.654 117.348 1.00 120.49 ? 68  GLU A CG   1 
ATOM   999  C CD   . GLU A 1 68  ? 65.631  99.843  118.232 1.00 120.49 ? 68  GLU A CD   1 
ATOM   1000 O OE1  . GLU A 1 68  ? 65.594  100.101 119.454 1.00 120.49 ? 68  GLU A OE1  1 
ATOM   1001 O OE2  . GLU A 1 68  ? 64.935  98.948  117.706 1.00 120.49 ? 68  GLU A OE2  1 
ATOM   1002 H H    . GLU A 1 68  ? 69.382  101.423 117.626 1.00 120.49 ? 68  GLU A H    1 
ATOM   1003 H HA   . GLU A 1 68  ? 67.633  102.803 116.266 1.00 120.49 ? 68  GLU A HA   1 
ATOM   1004 H HB2  . GLU A 1 68  ? 67.501  101.664 118.836 1.00 120.49 ? 68  GLU A HB2  1 
ATOM   1005 H HB3  . GLU A 1 68  ? 66.265  102.461 118.246 1.00 120.49 ? 68  GLU A HB3  1 
ATOM   1006 H HG2  . GLU A 1 68  ? 66.070  100.893 116.543 1.00 120.49 ? 68  GLU A HG2  1 
ATOM   1007 H HG3  . GLU A 1 68  ? 67.320  100.102 117.121 1.00 120.49 ? 68  GLU A HG3  1 
ATOM   1008 N N    . GLU A 1 69  ? 68.878  104.374 118.766 1.00 119.34 ? 69  GLU A N    1 
ATOM   1009 C CA   . GLU A 1 69  ? 68.991  105.698 119.369 1.00 119.34 ? 69  GLU A CA   1 
ATOM   1010 C C    . GLU A 1 69  ? 69.505  106.710 118.358 1.00 119.34 ? 69  GLU A C    1 
ATOM   1011 O O    . GLU A 1 69  ? 68.992  107.830 118.263 1.00 119.34 ? 69  GLU A O    1 
ATOM   1012 C CB   . GLU A 1 69  ? 69.908  105.632 120.590 1.00 119.34 ? 69  GLU A CB   1 
ATOM   1013 C CG   . GLU A 1 69  ? 69.794  106.820 121.530 1.00 119.34 ? 69  GLU A CG   1 
ATOM   1014 C CD   . GLU A 1 69  ? 70.567  106.615 122.819 1.00 119.34 ? 69  GLU A CD   1 
ATOM   1015 O OE1  . GLU A 1 69  ? 71.462  105.743 122.842 1.00 119.34 ? 69  GLU A OE1  1 
ATOM   1016 O OE2  . GLU A 1 69  ? 70.279  107.318 123.810 1.00 119.34 ? 69  GLU A OE2  1 
ATOM   1017 H H    . GLU A 1 69  ? 69.347  103.767 119.156 1.00 119.34 ? 69  GLU A H    1 
ATOM   1018 H HA   . GLU A 1 69  ? 68.121  106.000 119.658 1.00 119.34 ? 69  GLU A HA   1 
ATOM   1019 H HB2  . GLU A 1 69  ? 69.697  104.834 121.099 1.00 119.34 ? 69  GLU A HB2  1 
ATOM   1020 H HB3  . GLU A 1 69  ? 70.825  105.589 120.279 1.00 119.34 ? 69  GLU A HB3  1 
ATOM   1021 H HG2  . GLU A 1 69  ? 70.152  107.604 121.087 1.00 119.34 ? 69  GLU A HG2  1 
ATOM   1022 H HG3  . GLU A 1 69  ? 68.861  106.963 121.756 1.00 119.34 ? 69  GLU A HG3  1 
ATOM   1023 N N    . LEU A 1 70  ? 70.509  106.322 117.575 1.00 111.40 ? 70  LEU A N    1 
ATOM   1024 C CA   . LEU A 1 70  ? 71.082  107.240 116.600 1.00 111.40 ? 70  LEU A CA   1 
ATOM   1025 C C    . LEU A 1 70  ? 70.039  107.684 115.578 1.00 111.40 ? 70  LEU A C    1 
ATOM   1026 O O    . LEU A 1 70  ? 70.045  108.840 115.138 1.00 111.40 ? 70  LEU A O    1 
ATOM   1027 C CB   . LEU A 1 70  ? 72.270  106.565 115.914 1.00 111.40 ? 70  LEU A CB   1 
ATOM   1028 C CG   . LEU A 1 70  ? 73.222  107.429 115.085 1.00 111.40 ? 70  LEU A CG   1 
ATOM   1029 C CD1  . LEU A 1 70  ? 73.917  108.471 115.950 1.00 111.40 ? 70  LEU A CD1  1 
ATOM   1030 C CD2  . LEU A 1 70  ? 74.250  106.549 114.396 1.00 111.40 ? 70  LEU A CD2  1 
ATOM   1031 H H    . LEU A 1 70  ? 70.869  105.542 117.586 1.00 111.40 ? 70  LEU A H    1 
ATOM   1032 H HA   . LEU A 1 70  ? 71.408  108.031 117.057 1.00 111.40 ? 70  LEU A HA   1 
ATOM   1033 H HB2  . LEU A 1 70  ? 72.805  106.142 116.604 1.00 111.40 ? 70  LEU A HB2  1 
ATOM   1034 H HB3  . LEU A 1 70  ? 71.925  105.875 115.326 1.00 111.40 ? 70  LEU A HB3  1 
ATOM   1035 H HG   . LEU A 1 70  ? 72.719  107.894 114.398 1.00 111.40 ? 70  LEU A HG   1 
ATOM   1036 H HD11 . LEU A 1 70  ? 74.538  108.970 115.397 1.00 111.40 ? 70  LEU A HD11 1 
ATOM   1037 H HD12 . LEU A 1 70  ? 73.256  109.070 116.329 1.00 111.40 ? 70  LEU A HD12 1 
ATOM   1038 H HD13 . LEU A 1 70  ? 74.400  108.019 116.660 1.00 111.40 ? 70  LEU A HD13 1 
ATOM   1039 H HD21 . LEU A 1 70  ? 74.820  107.106 113.845 1.00 111.40 ? 70  LEU A HD21 1 
ATOM   1040 H HD22 . LEU A 1 70  ? 74.780  106.103 115.075 1.00 111.40 ? 70  LEU A HD22 1 
ATOM   1041 H HD23 . LEU A 1 70  ? 73.794  105.892 113.847 1.00 111.40 ? 70  LEU A HD23 1 
ATOM   1042 N N    . ASN A 1 71  ? 69.126  106.785 115.196 1.00 122.74 ? 71  ASN A N    1 
ATOM   1043 C CA   . ASN A 1 71  ? 68.295  107.037 114.021 1.00 122.74 ? 71  ASN A CA   1 
ATOM   1044 C C    . ASN A 1 71  ? 67.191  108.053 114.297 1.00 122.74 ? 71  ASN A C    1 
ATOM   1045 O O    . ASN A 1 71  ? 67.079  109.051 113.575 1.00 122.74 ? 71  ASN A O    1 
ATOM   1046 C CB   . ASN A 1 71  ? 67.726  105.716 113.507 1.00 122.74 ? 71  ASN A CB   1 
ATOM   1047 C CG   . ASN A 1 71  ? 66.233  105.772 113.226 1.00 122.74 ? 71  ASN A CG   1 
ATOM   1048 O OD1  . ASN A 1 71  ? 65.419  105.938 114.131 1.00 122.74 ? 71  ASN A OD1  1 
ATOM   1049 N ND2  . ASN A 1 71  ? 65.872  105.615 111.972 1.00 122.74 ? 71  ASN A ND2  1 
ATOM   1050 H H    . ASN A 1 71  ? 68.971  106.035 115.591 1.00 122.74 ? 71  ASN A H    1 
ATOM   1051 H HA   . ASN A 1 71  ? 68.859  107.397 113.318 1.00 122.74 ? 71  ASN A HA   1 
ATOM   1052 H HB2  . ASN A 1 71  ? 68.168  105.497 112.675 1.00 122.74 ? 71  ASN A HB2  1 
ATOM   1053 H HB3  . ASN A 1 71  ? 67.886  105.014 114.153 1.00 122.74 ? 71  ASN A HB3  1 
ATOM   1054 H HD22 . ASN A 1 71  ? 66.478  105.500 111.373 1.00 122.74 ? 71  ASN A HD22 1 
ATOM   1055 N N    . TYR A 1 72  ? 66.375  107.845 115.332 1.00 124.61 ? 72  TYR A N    1 
ATOM   1056 C CA   . TYR A 1 72  ? 65.237  108.730 115.550 1.00 124.61 ? 72  TYR A CA   1 
ATOM   1057 C C    . TYR A 1 72  ? 65.419  109.704 116.708 1.00 124.61 ? 72  TYR A C    1 
ATOM   1058 O O    . TYR A 1 72  ? 64.537  110.544 116.928 1.00 124.61 ? 72  TYR A O    1 
ATOM   1059 C CB   . TYR A 1 72  ? 63.932  107.936 115.728 1.00 124.61 ? 72  TYR A CB   1 
ATOM   1060 C CG   . TYR A 1 72  ? 63.819  106.931 116.858 1.00 124.61 ? 72  TYR A CG   1 
ATOM   1061 C CD1  . TYR A 1 72  ? 64.596  105.784 116.888 1.00 124.61 ? 72  TYR A CD1  1 
ATOM   1062 C CD2  . TYR A 1 72  ? 62.856  107.090 117.845 1.00 124.61 ? 72  TYR A CD2  1 
ATOM   1063 C CE1  . TYR A 1 72  ? 64.459  104.855 117.896 1.00 124.61 ? 72  TYR A CE1  1 
ATOM   1064 C CE2  . TYR A 1 72  ? 62.710  106.164 118.857 1.00 124.61 ? 72  TYR A CE2  1 
ATOM   1065 C CZ   . TYR A 1 72  ? 63.512  105.047 118.872 1.00 124.61 ? 72  TYR A CZ   1 
ATOM   1066 O OH   . TYR A 1 72  ? 63.372  104.121 119.881 1.00 124.61 ? 72  TYR A OH   1 
ATOM   1067 H H    . TYR A 1 72  ? 66.457  107.203 115.903 1.00 124.61 ? 72  TYR A H    1 
ATOM   1068 H HA   . TYR A 1 72  ? 65.113  109.257 114.749 1.00 124.61 ? 72  TYR A HA   1 
ATOM   1069 H HB2  . TYR A 1 72  ? 63.221  108.580 115.859 1.00 124.61 ? 72  TYR A HB2  1 
ATOM   1070 H HB3  . TYR A 1 72  ? 63.767  107.448 114.907 1.00 124.61 ? 72  TYR A HB3  1 
ATOM   1071 H HD1  . TYR A 1 72  ? 65.238  105.648 116.232 1.00 124.61 ? 72  TYR A HD1  1 
ATOM   1072 H HD2  . TYR A 1 72  ? 62.313  107.844 117.836 1.00 124.61 ? 72  TYR A HD2  1 
ATOM   1073 H HE1  . TYR A 1 72  ? 64.998  104.099 117.910 1.00 124.61 ? 72  TYR A HE1  1 
ATOM   1074 H HE2  . TYR A 1 72  ? 62.072  106.291 119.519 1.00 124.61 ? 72  TYR A HE2  1 
ATOM   1075 H HH   . TYR A 1 72  ? 62.718  104.326 120.366 1.00 124.61 ? 72  TYR A HH   1 
ATOM   1076 N N    . THR A 1 73  ? 66.549  109.658 117.421 1.00 118.88 ? 73  THR A N    1 
ATOM   1077 C CA   . THR A 1 73  ? 66.847  110.679 118.422 1.00 118.88 ? 73  THR A CA   1 
ATOM   1078 C C    . THR A 1 73  ? 67.672  111.834 117.873 1.00 118.88 ? 73  THR A C    1 
ATOM   1079 O O    . THR A 1 73  ? 67.593  112.940 118.417 1.00 118.88 ? 73  THR A O    1 
ATOM   1080 C CB   . THR A 1 73  ? 67.626  110.085 119.603 1.00 118.88 ? 73  THR A CB   1 
ATOM   1081 O OG1  . THR A 1 73  ? 68.809  109.443 119.111 1.00 118.88 ? 73  THR A OG1  1 
ATOM   1082 C CG2  . THR A 1 73  ? 66.790  109.077 120.389 1.00 118.88 ? 73  THR A CG2  1 
ATOM   1083 H H    . THR A 1 73  ? 67.157  109.052 117.338 1.00 118.88 ? 73  THR A H    1 
ATOM   1084 H HA   . THR A 1 73  ? 66.015  111.038 118.764 1.00 118.88 ? 73  THR A HA   1 
ATOM   1085 H HB   . THR A 1 73  ? 67.890  110.802 120.202 1.00 118.88 ? 73  THR A HB   1 
ATOM   1086 H HG1  . THR A 1 73  ? 69.412  109.470 119.691 1.00 118.88 ? 73  THR A HG1  1 
ATOM   1087 H HG21 . THR A 1 73  ? 67.230  108.877 121.231 1.00 118.88 ? 73  THR A HG21 1 
ATOM   1088 H HG22 . THR A 1 73  ? 65.909  109.440 120.571 1.00 118.88 ? 73  THR A HG22 1 
ATOM   1089 H HG23 . THR A 1 73  ? 66.697  108.254 119.886 1.00 118.88 ? 73  THR A HG23 1 
ATOM   1090 N N    . VAL A 1 74  ? 68.455  111.606 116.824 1.00 108.65 ? 74  VAL A N    1 
ATOM   1091 C CA   . VAL A 1 74  ? 69.409  112.592 116.316 1.00 108.65 ? 74  VAL A CA   1 
ATOM   1092 C C    . VAL A 1 74  ? 68.855  113.237 115.049 1.00 108.65 ? 74  VAL A C    1 
ATOM   1093 O O    . VAL A 1 74  ? 68.041  112.614 114.356 1.00 108.65 ? 74  VAL A O    1 
ATOM   1094 C CB   . VAL A 1 74  ? 70.768  111.927 116.041 1.00 108.65 ? 74  VAL A CB   1 
ATOM   1095 C CG1  . VAL A 1 74  ? 71.817  112.945 115.630 1.00 108.65 ? 74  VAL A CG1  1 
ATOM   1096 C CG2  . VAL A 1 74  ? 71.232  111.126 117.250 1.00 108.65 ? 74  VAL A CG2  1 
ATOM   1097 H H    . VAL A 1 74  ? 68.456  110.868 116.378 1.00 108.65 ? 74  VAL A H    1 
ATOM   1098 H HA   . VAL A 1 74  ? 69.540  113.282 116.988 1.00 108.65 ? 74  VAL A HA   1 
ATOM   1099 H HB   . VAL A 1 74  ? 70.650  111.308 115.309 1.00 108.65 ? 74  VAL A HB   1 
ATOM   1100 H HG11 . VAL A 1 74  ? 72.653  112.478 115.475 1.00 108.65 ? 74  VAL A HG11 1 
ATOM   1101 H HG12 . VAL A 1 74  ? 71.541  113.387 114.811 1.00 108.65 ? 74  VAL A HG12 1 
ATOM   1102 H HG13 . VAL A 1 74  ? 71.925  113.588 116.347 1.00 108.65 ? 74  VAL A HG13 1 
ATOM   1103 H HG21 . VAL A 1 74  ? 72.142  110.837 117.092 1.00 108.65 ? 74  VAL A HG21 1 
ATOM   1104 H HG22 . VAL A 1 74  ? 71.196  111.692 118.036 1.00 108.65 ? 74  VAL A HG22 1 
ATOM   1105 H HG23 . VAL A 1 74  ? 70.657  110.351 117.369 1.00 108.65 ? 74  VAL A HG23 1 
ATOM   1106 N N    . PRO A 1 75  ? 69.260  114.459 114.697 1.00 107.37 ? 75  PRO A N    1 
ATOM   1107 C CA   . PRO A 1 75  ? 68.861  115.010 113.396 1.00 107.37 ? 75  PRO A CA   1 
ATOM   1108 C C    . PRO A 1 75  ? 69.397  114.182 112.240 1.00 107.37 ? 75  PRO A C    1 
ATOM   1109 O O    . PRO A 1 75  ? 70.528  113.695 112.271 1.00 107.37 ? 75  PRO A O    1 
ATOM   1110 C CB   . PRO A 1 75  ? 69.469  116.417 113.406 1.00 107.37 ? 75  PRO A CB   1 
ATOM   1111 C CG   . PRO A 1 75  ? 69.574  116.772 114.841 1.00 107.37 ? 75  PRO A CG   1 
ATOM   1112 C CD   . PRO A 1 75  ? 69.851  115.491 115.569 1.00 107.37 ? 75  PRO A CD   1 
ATOM   1113 H HA   . PRO A 1 75  ? 67.895  115.069 113.322 1.00 107.37 ? 75  PRO A HA   1 
ATOM   1114 H HB2  . PRO A 1 75  ? 70.347  116.390 112.993 1.00 107.37 ? 75  PRO A HB2  1 
ATOM   1115 H HB3  . PRO A 1 75  ? 68.878  117.027 112.938 1.00 107.37 ? 75  PRO A HB3  1 
ATOM   1116 H HG2  . PRO A 1 75  ? 70.299  117.406 114.963 1.00 107.37 ? 75  PRO A HG2  1 
ATOM   1117 H HG3  . PRO A 1 75  ? 68.741  117.156 115.148 1.00 107.37 ? 75  PRO A HG3  1 
ATOM   1118 H HD2  . PRO A 1 75  ? 70.804  115.359 115.643 1.00 107.37 ? 75  PRO A HD2  1 
ATOM   1119 H HD3  . PRO A 1 75  ? 69.414  115.496 116.436 1.00 107.37 ? 75  PRO A HD3  1 
ATOM   1120 N N    . GLY A 1 76  ? 68.571  114.037 111.207 1.00 108.36 ? 76  GLY A N    1 
ATOM   1121 C CA   . GLY A 1 76  ? 68.959  113.228 110.068 1.00 108.36 ? 76  GLY A CA   1 
ATOM   1122 C C    . GLY A 1 76  ? 70.113  113.836 109.293 1.00 108.36 ? 76  GLY A C    1 
ATOM   1123 O O    . GLY A 1 76  ? 70.324  115.049 109.287 1.00 108.36 ? 76  GLY A O    1 
ATOM   1124 H H    . GLY A 1 76  ? 67.785  114.387 111.150 1.00 108.36 ? 76  GLY A H    1 
ATOM   1125 H HA2  . GLY A 1 76  ? 69.232  112.345 110.365 1.00 108.36 ? 76  GLY A HA2  1 
ATOM   1126 H HA3  . GLY A 1 76  ? 68.200  113.141 109.468 1.00 108.36 ? 76  GLY A HA3  1 
ATOM   1127 N N    . LEU A 1 77  ? 70.865  112.966 108.625 1.00 107.64 ? 77  LEU A N    1 
ATOM   1128 C CA   . LEU A 1 77  ? 72.000  113.358 107.801 1.00 107.64 ? 77  LEU A CA   1 
ATOM   1129 C C    . LEU A 1 77  ? 71.582  113.450 106.338 1.00 107.64 ? 77  LEU A C    1 
ATOM   1130 O O    . LEU A 1 77  ? 70.526  112.959 105.930 1.00 107.64 ? 77  LEU A O    1 
ATOM   1131 C CB   . LEU A 1 77  ? 73.153  112.360 107.958 1.00 107.64 ? 77  LEU A CB   1 
ATOM   1132 C CG   . LEU A 1 77  ? 72.955  110.999 107.279 1.00 107.64 ? 77  LEU A CG   1 
ATOM   1133 C CD1  . LEU A 1 77  ? 73.635  110.959 105.909 1.00 107.64 ? 77  LEU A CD1  1 
ATOM   1134 C CD2  . LEU A 1 77  ? 73.475  109.874 108.164 1.00 107.64 ? 77  LEU A CD2  1 
ATOM   1135 H H    . LEU A 1 77  ? 70.723  112.116 108.638 1.00 107.64 ? 77  LEU A H    1 
ATOM   1136 H HA   . LEU A 1 77  ? 72.320  114.235 108.069 1.00 107.64 ? 77  LEU A HA   1 
ATOM   1137 H HB2  . LEU A 1 77  ? 73.956  112.752 107.578 1.00 107.64 ? 77  LEU A HB2  1 
ATOM   1138 H HB3  . LEU A 1 77  ? 73.287  112.194 108.904 1.00 107.64 ? 77  LEU A HB3  1 
ATOM   1139 H HG   . LEU A 1 77  ? 72.004  110.850 107.143 1.00 107.64 ? 77  LEU A HG   1 
ATOM   1140 H HD11 . LEU A 1 77  ? 73.571  110.056 105.559 1.00 107.64 ? 77  LEU A HD11 1 
ATOM   1141 H HD12 . LEU A 1 77  ? 73.194  111.578 105.308 1.00 107.64 ? 77  LEU A HD12 1 
ATOM   1142 H HD13 . LEU A 1 77  ? 74.566  111.205 106.012 1.00 107.64 ? 77  LEU A HD13 1 
ATOM   1143 H HD21 . LEU A 1 77  ? 73.342  109.032 107.704 1.00 107.64 ? 77  LEU A HD21 1 
ATOM   1144 H HD22 . LEU A 1 77  ? 74.418  110.016 108.330 1.00 107.64 ? 77  LEU A HD22 1 
ATOM   1145 H HD23 . LEU A 1 77  ? 72.987  109.878 109.002 1.00 107.64 ? 77  LEU A HD23 1 
ATOM   1146 N N    . GLY A 1 78  ? 72.436  114.090 105.543 1.00 110.48 ? 78  GLY A N    1 
ATOM   1147 C CA   . GLY A 1 78  ? 72.192  114.253 104.126 1.00 110.48 ? 78  GLY A CA   1 
ATOM   1148 C C    . GLY A 1 78  ? 71.481  115.528 103.730 1.00 110.48 ? 78  GLY A C    1 
ATOM   1149 O O    . GLY A 1 78  ? 71.161  115.693 102.546 1.00 110.48 ? 78  GLY A O    1 
ATOM   1150 H H    . GLY A 1 78  ? 73.178  114.438 105.806 1.00 110.48 ? 78  GLY A H    1 
ATOM   1151 H HA2  . GLY A 1 78  ? 73.046  114.230 103.665 1.00 110.48 ? 78  GLY A HA2  1 
ATOM   1152 H HA3  . GLY A 1 78  ? 71.665  113.506 103.807 1.00 110.48 ? 78  GLY A HA3  1 
ATOM   1153 N N    . ALA A 1 79  ? 71.231  116.436 104.672 1.00 112.29 ? 79  ALA A N    1 
ATOM   1154 C CA   . ALA A 1 79  ? 70.595  117.716 104.393 1.00 112.29 ? 79  ALA A CA   1 
ATOM   1155 C C    . ALA A 1 79  ? 71.617  118.835 104.534 1.00 112.29 ? 79  ALA A C    1 
ATOM   1156 O O    . ALA A 1 79  ? 72.407  118.843 105.485 1.00 112.29 ? 79  ALA A O    1 
ATOM   1157 C CB   . ALA A 1 79  ? 69.418  117.966 105.339 1.00 112.29 ? 79  ALA A CB   1 
ATOM   1158 H H    . ALA A 1 79  ? 71.424  116.332 105.502 1.00 112.29 ? 79  ALA A H    1 
ATOM   1159 H HA   . ALA A 1 79  ? 70.257  117.711 103.483 1.00 112.29 ? 79  ALA A HA   1 
ATOM   1160 H HB1  . ALA A 1 79  ? 69.732  117.973 106.254 1.00 112.29 ? 79  ALA A HB1  1 
ATOM   1161 H HB2  . ALA A 1 79  ? 69.023  118.824 105.125 1.00 112.29 ? 79  ALA A HB2  1 
ATOM   1162 H HB3  . ALA A 1 79  ? 68.766  117.262 105.219 1.00 112.29 ? 79  ALA A HB3  1 
ATOM   1163 N N    . ALA A 1 80  ? 71.598  119.775 103.587 1.00 112.96 ? 80  ALA A N    1 
ATOM   1164 C CA   . ALA A 1 80  ? 72.547  120.887 103.559 1.00 112.96 ? 80  ALA A CA   1 
ATOM   1165 C C    . ALA A 1 80  ? 73.954  120.411 103.917 1.00 112.96 ? 80  ALA A C    1 
ATOM   1166 O O    . ALA A 1 80  ? 74.641  120.979 104.768 1.00 112.96 ? 80  ALA A O    1 
ATOM   1167 C CB   . ALA A 1 80  ? 72.089  122.010 104.488 1.00 112.96 ? 80  ALA A CB   1 
ATOM   1168 H H    . ALA A 1 80  ? 71.035  119.801 102.938 1.00 112.96 ? 80  ALA A H    1 
ATOM   1169 H HA   . ALA A 1 80  ? 72.580  121.251 102.663 1.00 112.96 ? 80  ALA A HA   1 
ATOM   1170 H HB1  . ALA A 1 80  ? 72.715  122.743 104.427 1.00 112.96 ? 80  ALA A HB1  1 
ATOM   1171 H HB2  . ALA A 1 80  ? 71.210  122.310 104.217 1.00 112.96 ? 80  ALA A HB2  1 
ATOM   1172 H HB3  . ALA A 1 80  ? 72.056  121.664 105.390 1.00 112.96 ? 80  ALA A HB3  1 
ATOM   1173 N N    . GLY A 1 81  ? 74.386  119.354 103.236 1.00 110.58 ? 81  GLY A N    1 
ATOM   1174 C CA   . GLY A 1 81  ? 75.655  118.720 103.529 1.00 110.58 ? 81  GLY A CA   1 
ATOM   1175 C C    . GLY A 1 81  ? 75.489  117.238 103.777 1.00 110.58 ? 81  GLY A C    1 
ATOM   1176 O O    . GLY A 1 81  ? 74.394  116.785 104.129 1.00 110.58 ? 81  GLY A O    1 
ATOM   1177 H H    . GLY A 1 81  ? 73.956  118.987 102.580 1.00 110.58 ? 81  GLY A H    1 
ATOM   1178 H HA2  . GLY A 1 81  ? 76.254  118.832 102.773 1.00 110.58 ? 81  GLY A HA2  1 
ATOM   1179 H HA3  . GLY A 1 81  ? 76.064  119.121 104.316 1.00 110.58 ? 81  GLY A HA3  1 
ATOM   1180 N N    . GLU A 1 82  ? 76.566  116.468 103.599 1.00 111.28 ? 82  GLU A N    1 
ATOM   1181 C CA   . GLU A 1 82  ? 76.461  115.020 103.735 1.00 111.28 ? 82  GLU A CA   1 
ATOM   1182 C C    . GLU A 1 82  ? 76.114  114.630 105.167 1.00 111.28 ? 82  GLU A C    1 
ATOM   1183 O O    . GLU A 1 82  ? 75.179  113.858 105.403 1.00 111.28 ? 82  GLU A O    1 
ATOM   1184 C CB   . GLU A 1 82  ? 77.769  114.360 103.300 1.00 111.28 ? 82  GLU A CB   1 
ATOM   1185 H H    . GLU A 1 82  ? 77.360  116.750 103.405 1.00 111.28 ? 82  GLU A H    1 
ATOM   1186 H HA   . GLU A 1 82  ? 75.757  114.690 103.157 1.00 111.28 ? 82  GLU A HA   1 
ATOM   1187 N N    . ALA A 1 83  ? 76.878  115.139 106.146 1.00 104.76 ? 83  ALA A N    1 
ATOM   1188 C CA   . ALA A 1 83  ? 76.572  114.832 107.541 1.00 104.76 ? 83  ALA A CA   1 
ATOM   1189 C C    . ALA A 1 83  ? 76.750  116.033 108.467 1.00 104.76 ? 83  ALA A C    1 
ATOM   1190 O O    . ALA A 1 83  ? 76.896  115.838 109.679 1.00 104.76 ? 83  ALA A O    1 
ATOM   1191 C CB   . ALA A 1 83  ? 77.446  113.667 108.036 1.00 104.76 ? 83  ALA A CB   1 
ATOM   1192 H H    . ALA A 1 83  ? 77.557  115.653 106.027 1.00 104.76 ? 83  ALA A H    1 
ATOM   1193 H HA   . ALA A 1 83  ? 75.646  114.551 107.613 1.00 104.76 ? 83  ALA A HA   1 
ATOM   1194 H HB1  . ALA A 1 83  ? 77.221  113.472 108.958 1.00 104.76 ? 83  ALA A HB1  1 
ATOM   1195 H HB2  . ALA A 1 83  ? 77.267  112.890 107.485 1.00 104.76 ? 83  ALA A HB2  1 
ATOM   1196 H HB3  . ALA A 1 83  ? 78.380  113.919 107.969 1.00 104.76 ? 83  ALA A HB3  1 
ATOM   1197 N N    . PHE A 1 84  ? 76.746  117.259 107.943 1.00 103.75 ? 84  PHE A N    1 
ATOM   1198 C CA   . PHE A 1 84  ? 76.919  118.424 108.805 1.00 103.75 ? 84  PHE A CA   1 
ATOM   1199 C C    . PHE A 1 84  ? 75.839  118.540 109.871 1.00 103.75 ? 84  PHE A C    1 
ATOM   1200 O O    . PHE A 1 84  ? 76.188  118.787 111.038 1.00 103.75 ? 84  PHE A O    1 
ATOM   1201 C CB   . PHE A 1 84  ? 76.970  119.697 107.948 1.00 103.75 ? 84  PHE A CB   1 
ATOM   1202 C CG   . PHE A 1 84  ? 76.928  120.974 108.747 1.00 103.75 ? 84  PHE A CG   1 
ATOM   1203 C CD1  . PHE A 1 84  ? 78.098  121.567 109.195 1.00 103.75 ? 84  PHE A CD1  1 
ATOM   1204 C CD2  . PHE A 1 84  ? 75.720  121.590 109.039 1.00 103.75 ? 84  PHE A CD2  1 
ATOM   1205 C CE1  . PHE A 1 84  ? 78.063  122.743 109.922 1.00 103.75 ? 84  PHE A CE1  1 
ATOM   1206 C CE2  . PHE A 1 84  ? 75.681  122.766 109.768 1.00 103.75 ? 84  PHE A CE2  1 
ATOM   1207 C CZ   . PHE A 1 84  ? 76.853  123.342 110.209 1.00 103.75 ? 84  PHE A CZ   1 
ATOM   1208 H H    . PHE A 1 84  ? 76.642  117.439 107.107 1.00 103.75 ? 84  PHE A H    1 
ATOM   1209 H HA   . PHE A 1 84  ? 77.768  118.342 109.265 1.00 103.75 ? 84  PHE A HA   1 
ATOM   1210 H HB2  . PHE A 1 84  ? 77.797  119.692 107.442 1.00 103.75 ? 84  PHE A HB2  1 
ATOM   1211 H HB3  . PHE A 1 84  ? 76.216  119.706 107.340 1.00 103.75 ? 84  PHE A HB3  1 
ATOM   1212 H HD1  . PHE A 1 84  ? 78.916  121.169 109.006 1.00 103.75 ? 84  PHE A HD1  1 
ATOM   1213 H HD2  . PHE A 1 84  ? 74.925  121.206 108.745 1.00 103.75 ? 84  PHE A HD2  1 
ATOM   1214 H HE1  . PHE A 1 84  ? 78.855  123.129 110.219 1.00 103.75 ? 84  PHE A HE1  1 
ATOM   1215 H HE2  . PHE A 1 84  ? 74.866  123.169 109.960 1.00 103.75 ? 84  PHE A HE2  1 
ATOM   1216 H HZ   . PHE A 1 84  ? 76.828  124.133 110.699 1.00 103.75 ? 84  PHE A HZ   1 
ATOM   1217 N N    . PRO A 1 85  ? 74.547  118.394 109.564 1.00 104.09 ? 85  PRO A N    1 
ATOM   1218 C CA   . PRO A 1 85  ? 73.544  118.532 110.633 1.00 104.09 ? 85  PRO A CA   1 
ATOM   1219 C C    . PRO A 1 85  ? 73.665  117.455 111.695 1.00 104.09 ? 85  PRO A C    1 
ATOM   1220 O O    . PRO A 1 85  ? 73.725  117.767 112.891 1.00 104.09 ? 85  PRO A O    1 
ATOM   1221 C CB   . PRO A 1 85  ? 72.209  118.457 109.874 1.00 104.09 ? 85  PRO A CB   1 
ATOM   1222 C CG   . PRO A 1 85  ? 72.547  118.729 108.445 1.00 104.09 ? 85  PRO A CG   1 
ATOM   1223 C CD   . PRO A 1 85  ? 73.917  118.164 108.255 1.00 104.09 ? 85  PRO A CD   1 
ATOM   1224 H HA   . PRO A 1 85  ? 73.623  119.403 111.047 1.00 104.09 ? 85  PRO A HA   1 
ATOM   1225 H HB2  . PRO A 1 85  ? 71.821  117.575 109.974 1.00 104.09 ? 85  PRO A HB2  1 
ATOM   1226 H HB3  . PRO A 1 85  ? 71.604  119.135 110.215 1.00 104.09 ? 85  PRO A HB3  1 
ATOM   1227 H HG2  . PRO A 1 85  ? 71.906  118.287 107.868 1.00 104.09 ? 85  PRO A HG2  1 
ATOM   1228 H HG3  . PRO A 1 85  ? 72.547  119.686 108.286 1.00 104.09 ? 85  PRO A HG3  1 
ATOM   1229 H HD2  . PRO A 1 85  ? 73.867  117.214 108.063 1.00 104.09 ? 85  PRO A HD2  1 
ATOM   1230 H HD3  . PRO A 1 85  ? 74.383  118.647 107.557 1.00 104.09 ? 85  PRO A HD3  1 
ATOM   1231 N N    . ARG A 1 86  ? 73.721  116.187 111.288 1.00 101.83 ? 86  ARG A N    1 
ATOM   1232 C CA   . ARG A 1 86  ? 73.702  115.103 112.262 1.00 101.83 ? 86  ARG A CA   1 
ATOM   1233 C C    . ARG A 1 86  ? 74.894  115.182 113.205 1.00 101.83 ? 86  ARG A C    1 
ATOM   1234 O O    . ARG A 1 86  ? 74.761  114.922 114.406 1.00 101.83 ? 86  ARG A O    1 
ATOM   1235 C CB   . ARG A 1 86  ? 73.683  113.755 111.544 1.00 101.83 ? 86  ARG A CB   1 
ATOM   1236 C CG   . ARG A 1 86  ? 73.624  112.564 112.484 1.00 101.83 ? 86  ARG A CG   1 
ATOM   1237 C CD   . ARG A 1 86  ? 73.580  111.259 111.713 1.00 101.83 ? 86  ARG A CD   1 
ATOM   1238 N NE   . ARG A 1 86  ? 74.807  111.021 110.962 1.00 101.83 ? 86  ARG A NE   1 
ATOM   1239 C CZ   . ARG A 1 86  ? 75.895  110.440 111.453 1.00 101.83 ? 86  ARG A CZ   1 
ATOM   1240 N NH1  . ARG A 1 86  ? 75.957  110.031 112.713 1.00 101.83 ? 86  ARG A NH1  1 
ATOM   1241 N NH2  . ARG A 1 86  ? 76.949  110.263 110.659 1.00 101.83 ? 86  ARG A NH2  1 
ATOM   1242 H H    . ARG A 1 86  ? 73.764  115.932 110.468 1.00 101.83 ? 86  ARG A H    1 
ATOM   1243 H HA   . ARG A 1 86  ? 72.894  115.168 112.795 1.00 101.83 ? 86  ARG A HA   1 
ATOM   1244 H HB2  . ARG A 1 86  ? 72.904  113.717 110.965 1.00 101.83 ? 86  ARG A HB2  1 
ATOM   1245 H HB3  . ARG A 1 86  ? 74.491  113.676 111.015 1.00 101.83 ? 86  ARG A HB3  1 
ATOM   1246 H HG2  . ARG A 1 86  ? 74.407  112.553 113.057 1.00 101.83 ? 86  ARG A HG2  1 
ATOM   1247 H HG3  . ARG A 1 86  ? 72.820  112.630 113.020 1.00 101.83 ? 86  ARG A HG3  1 
ATOM   1248 H HD2  . ARG A 1 86  ? 73.447  110.526 112.331 1.00 101.83 ? 86  ARG A HD2  1 
ATOM   1249 H HD3  . ARG A 1 86  ? 72.844  111.298 111.081 1.00 101.83 ? 86  ARG A HD3  1 
ATOM   1250 H HE   . ARG A 1 86  ? 74.817  111.252 110.133 1.00 101.83 ? 86  ARG A HE   1 
ATOM   1251 H HH11 . ARG A 1 86  ? 76.673  109.656 113.007 1.00 101.83 ? 86  ARG A HH11 1 
ATOM   1252 H HH12 . ARG A 1 86  ? 75.286  110.137 113.236 1.00 101.83 ? 86  ARG A HH12 1 
ATOM   1253 H HH21 . ARG A 1 86  ? 76.921  110.524 109.842 1.00 101.83 ? 86  ARG A HH21 1 
ATOM   1254 H HH22 . ARG A 1 86  ? 77.659  109.888 110.966 1.00 101.83 ? 86  ARG A HH22 1 
ATOM   1255 N N    . GLN A 1 87  ? 76.070  115.532 112.683 1.00 92.67  ? 87  GLN A N    1 
ATOM   1256 C CA   . GLN A 1 87  ? 77.282  115.439 113.484 1.00 92.67  ? 87  GLN A CA   1 
ATOM   1257 C C    . GLN A 1 87  ? 77.199  116.321 114.721 1.00 92.67  ? 87  GLN A C    1 
ATOM   1258 O O    . GLN A 1 87  ? 77.340  115.839 115.850 1.00 92.67  ? 87  GLN A O    1 
ATOM   1259 C CB   . GLN A 1 87  ? 78.505  115.820 112.648 1.00 30.00  ? 87  GLN A CB   1 
ATOM   1260 C CG   . GLN A 1 87  ? 78.807  114.857 111.513 1.00 30.00  ? 87  GLN A CG   1 
ATOM   1261 C CD   . GLN A 1 87  ? 79.081  113.449 111.999 1.00 30.00  ? 87  GLN A CD   1 
ATOM   1262 O OE1  . GLN A 1 87  ? 79.743  113.255 113.019 1.00 30.00  ? 87  GLN A OE1  1 
ATOM   1263 N NE2  . GLN A 1 87  ? 78.570  112.460 111.271 1.00 30.00  ? 87  GLN A NE2  1 
ATOM   1264 H H    . GLN A 1 87  ? 76.200  115.829 111.884 1.00 92.67  ? 87  GLN A H    1 
ATOM   1265 H HA   . GLN A 1 87  ? 77.390  114.521 113.780 1.00 92.67  ? 87  GLN A HA   1 
ATOM   1266 N N    . CYS A 1 88  ? 76.958  117.617 114.537 1.00 90.03  ? 88  CYS A N    1 
ATOM   1267 C CA   . CYS A 1 88  ? 77.054  118.555 115.651 1.00 90.03  ? 88  CYS A CA   1 
ATOM   1268 C C    . CYS A 1 88  ? 75.929  119.585 115.620 1.00 90.03  ? 88  CYS A C    1 
ATOM   1269 O O    . CYS A 1 88  ? 76.149  120.780 115.815 1.00 90.03  ? 88  CYS A O    1 
ATOM   1270 C CB   . CYS A 1 88  ? 78.419  119.236 115.660 1.00 90.03  ? 88  CYS A CB   1 
ATOM   1271 S SG   . CYS A 1 88  ? 79.111  119.632 114.047 1.00 90.03  ? 88  CYS A SG   1 
ATOM   1272 H H    . CYS A 1 88  ? 76.738  117.977 113.787 1.00 90.03  ? 88  CYS A H    1 
ATOM   1273 H HA   . CYS A 1 88  ? 76.969  118.060 116.480 1.00 90.03  ? 88  CYS A HA   1 
ATOM   1274 H HB2  . CYS A 1 88  ? 78.360  120.058 116.172 1.00 90.03  ? 88  CYS A HB2  1 
ATOM   1275 H HB3  . CYS A 1 88  ? 79.045  118.633 116.090 1.00 90.03  ? 88  CYS A HB3  1 
ATOM   1276 N N    . ARG A 1 89  ? 74.697  119.131 115.397 1.00 100.54 ? 89  ARG A N    1 
ATOM   1277 C CA   . ARG A 1 89  ? 73.520  119.977 115.555 1.00 100.54 ? 89  ARG A CA   1 
ATOM   1278 C C    . ARG A 1 89  ? 72.521  119.274 116.461 1.00 100.54 ? 89  ARG A C    1 
ATOM   1279 O O    . ARG A 1 89  ? 72.282  118.073 116.317 1.00 100.54 ? 89  ARG A O    1 
ATOM   1280 C CB   . ARG A 1 89  ? 72.854  120.304 114.211 1.00 100.54 ? 89  ARG A CB   1 
ATOM   1281 C CG   . ARG A 1 89  ? 73.720  121.063 113.204 1.00 100.54 ? 89  ARG A CG   1 
ATOM   1282 C CD   . ARG A 1 89  ? 74.383  122.297 113.794 1.00 100.54 ? 89  ARG A CD   1 
ATOM   1283 N NE   . ARG A 1 89  ? 73.496  123.028 114.687 1.00 100.54 ? 89  ARG A NE   1 
ATOM   1284 C CZ   . ARG A 1 89  ? 72.600  123.921 114.289 1.00 100.54 ? 89  ARG A CZ   1 
ATOM   1285 N NH1  . ARG A 1 89  ? 72.439  124.218 113.008 1.00 100.54 ? 89  ARG A NH1  1 
ATOM   1286 N NH2  . ARG A 1 89  ? 71.845  124.530 115.199 1.00 100.54 ? 89  ARG A NH2  1 
ATOM   1287 H H    . ARG A 1 89  ? 74.519  118.320 115.165 1.00 100.54 ? 89  ARG A H    1 
ATOM   1288 H HA   . ARG A 1 89  ? 73.768  120.807 115.991 1.00 100.54 ? 89  ARG A HA   1 
ATOM   1289 H HB2  . ARG A 1 89  ? 72.578  119.474 113.796 1.00 100.54 ? 89  ARG A HB2  1 
ATOM   1290 H HB3  . ARG A 1 89  ? 72.069  120.844 114.385 1.00 100.54 ? 89  ARG A HB3  1 
ATOM   1291 H HG2  . ARG A 1 89  ? 74.415  120.478 112.867 1.00 100.54 ? 89  ARG A HG2  1 
ATOM   1292 H HG3  . ARG A 1 89  ? 73.154  121.362 112.476 1.00 100.54 ? 89  ARG A HG3  1 
ATOM   1293 H HD2  . ARG A 1 89  ? 75.169  122.036 114.292 1.00 100.54 ? 89  ARG A HD2  1 
ATOM   1294 H HD3  . ARG A 1 89  ? 74.640  122.889 113.071 1.00 100.54 ? 89  ARG A HD3  1 
ATOM   1295 H HE   . ARG A 1 89  ? 73.591  122.904 115.533 1.00 100.54 ? 89  ARG A HE   1 
ATOM   1296 H HH11 . ARG A 1 89  ? 72.919  123.834 112.410 1.00 100.54 ? 89  ARG A HH11 1 
ATOM   1297 H HH12 . ARG A 1 89  ? 71.850  124.800 112.775 1.00 100.54 ? 89  ARG A HH12 1 
ATOM   1298 H HH21 . ARG A 1 89  ? 71.940  124.343 116.032 1.00 100.54 ? 89  ARG A HH21 1 
ATOM   1299 H HH22 . ARG A 1 89  ? 71.259  125.109 114.951 1.00 100.54 ? 89  ARG A HH22 1 
ATOM   1300 N N    . ARG A 1 90  ? 71.928  120.029 117.383 1.00 100.27 ? 90  ARG A N    1 
ATOM   1301 C CA   . ARG A 1 90  ? 71.044  119.483 118.407 1.00 100.27 ? 90  ARG A CA   1 
ATOM   1302 C C    . ARG A 1 90  ? 69.689  120.163 118.293 1.00 100.27 ? 90  ARG A C    1 
ATOM   1303 O O    . ARG A 1 90  ? 69.606  121.395 118.340 1.00 100.27 ? 90  ARG A O    1 
ATOM   1304 C CB   . ARG A 1 90  ? 71.633  119.683 119.808 1.00 100.27 ? 90  ARG A CB   1 
ATOM   1305 C CG   . ARG A 1 90  ? 70.913  118.914 120.909 1.00 100.27 ? 90  ARG A CG   1 
ATOM   1306 C CD   . ARG A 1 90  ? 71.614  119.073 122.251 1.00 100.27 ? 90  ARG A CD   1 
ATOM   1307 N NE   . ARG A 1 90  ? 71.597  120.454 122.719 1.00 100.27 ? 90  ARG A NE   1 
ATOM   1308 C CZ   . ARG A 1 90  ? 70.654  120.977 123.492 1.00 100.27 ? 90  ARG A CZ   1 
ATOM   1309 N NH1  . ARG A 1 90  ? 69.622  120.259 123.913 1.00 100.27 ? 90  ARG A NH1  1 
ATOM   1310 N NH2  . ARG A 1 90  ? 70.747  122.255 123.855 1.00 100.27 ? 90  ARG A NH2  1 
ATOM   1311 H H    . ARG A 1 90  ? 72.017  120.886 117.432 1.00 100.27 ? 90  ARG A H    1 
ATOM   1312 H HA   . ARG A 1 90  ? 70.917  118.531 118.267 1.00 100.27 ? 90  ARG A HA   1 
ATOM   1313 H HB2  . ARG A 1 90  ? 72.558  119.391 119.802 1.00 100.27 ? 90  ARG A HB2  1 
ATOM   1314 H HB3  . ARG A 1 90  ? 71.591  120.625 120.035 1.00 100.27 ? 90  ARG A HB3  1 
ATOM   1315 H HG2  . ARG A 1 90  ? 70.004  119.240 121.000 1.00 100.27 ? 90  ARG A HG2  1 
ATOM   1316 H HG3  . ARG A 1 90  ? 70.913  117.971 120.687 1.00 100.27 ? 90  ARG A HG3  1 
ATOM   1317 H HD2  . ARG A 1 90  ? 71.171  118.518 122.911 1.00 100.27 ? 90  ARG A HD2  1 
ATOM   1318 H HD3  . ARG A 1 90  ? 72.539  118.795 122.161 1.00 100.27 ? 90  ARG A HD3  1 
ATOM   1319 H HE   . ARG A 1 90  ? 72.273  120.947 122.521 1.00 100.27 ? 90  ARG A HE   1 
ATOM   1320 H HH11 . ARG A 1 90  ? 69.023  120.619 124.414 1.00 100.27 ? 90  ARG A HH11 1 
ATOM   1321 H HH12 . ARG A 1 90  ? 69.548  119.435 123.688 1.00 100.27 ? 90  ARG A HH12 1 
ATOM   1322 H HH21 . ARG A 1 90  ? 71.410  122.732 123.590 1.00 100.27 ? 90  ARG A HH21 1 
ATOM   1323 H HH22 . ARG A 1 90  ? 70.141  122.603 124.356 1.00 100.27 ? 90  ARG A HH22 1 
ATOM   1324 N N    . TYR A 1 91  ? 68.633  119.361 118.133 1.00 110.45 ? 91  TYR A N    1 
ATOM   1325 C CA   . TYR A 1 91  ? 67.290  119.920 118.036 1.00 110.45 ? 91  TYR A CA   1 
ATOM   1326 C C    . TYR A 1 91  ? 66.933  120.713 119.286 1.00 110.45 ? 91  TYR A C    1 
ATOM   1327 O O    . TYR A 1 91  ? 66.304  121.773 119.202 1.00 110.45 ? 91  TYR A O    1 
ATOM   1328 C CB   . TYR A 1 91  ? 66.270  118.801 117.801 1.00 110.45 ? 91  TYR A CB   1 
ATOM   1329 C CG   . TYR A 1 91  ? 66.189  118.309 116.368 1.00 110.45 ? 91  TYR A CG   1 
ATOM   1330 C CD1  . TYR A 1 91  ? 66.170  119.201 115.305 1.00 110.45 ? 91  TYR A CD1  1 
ATOM   1331 C CD2  . TYR A 1 91  ? 66.127  116.954 116.082 1.00 110.45 ? 91  TYR A CD2  1 
ATOM   1332 C CE1  . TYR A 1 91  ? 66.096  118.758 114.000 1.00 110.45 ? 91  TYR A CE1  1 
ATOM   1333 C CE2  . TYR A 1 91  ? 66.053  116.501 114.780 1.00 110.45 ? 91  TYR A CE2  1 
ATOM   1334 C CZ   . TYR A 1 91  ? 66.039  117.408 113.748 1.00 110.45 ? 91  TYR A CZ   1 
ATOM   1335 O OH   . TYR A 1 91  ? 65.966  116.959 112.450 1.00 110.45 ? 91  TYR A OH   1 
ATOM   1336 H H    . TYR A 1 91  ? 68.666  118.504 118.092 1.00 110.45 ? 91  TYR A H    1 
ATOM   1337 H HA   . TYR A 1 91  ? 67.259  120.531 117.284 1.00 110.45 ? 91  TYR A HA   1 
ATOM   1338 H HB2  . TYR A 1 91  ? 66.505  118.042 118.357 1.00 110.45 ? 91  TYR A HB2  1 
ATOM   1339 H HB3  . TYR A 1 91  ? 65.389  119.123 118.050 1.00 110.45 ? 91  TYR A HB3  1 
ATOM   1340 H HD1  . TYR A 1 91  ? 66.209  120.115 115.472 1.00 110.45 ? 91  TYR A HD1  1 
ATOM   1341 H HD2  . TYR A 1 91  ? 66.138  116.336 116.776 1.00 110.45 ? 91  TYR A HD2  1 
ATOM   1342 H HE1  . TYR A 1 91  ? 66.086  119.366 113.300 1.00 110.45 ? 91  TYR A HE1  1 
ATOM   1343 H HE2  . TYR A 1 91  ? 66.014  115.591 114.601 1.00 110.45 ? 91  TYR A HE2  1 
ATOM   1344 H HH   . TYR A 1 91  ? 66.084  116.128 112.431 1.00 110.45 ? 91  TYR A HH   1 
ATOM   1345 N N    . GLU A 1 92  ? 67.319  120.211 120.458 1.00 107.94 ? 92  GLU A N    1 
ATOM   1346 C CA   . GLU A 1 92  ? 67.054  120.855 121.740 1.00 107.94 ? 92  GLU A CA   1 
ATOM   1347 C C    . GLU A 1 92  ? 65.584  120.796 122.131 1.00 107.94 ? 92  GLU A C    1 
ATOM   1348 O O    . GLU A 1 92  ? 65.129  121.597 122.954 1.00 107.94 ? 92  GLU A O    1 
ATOM   1349 C CB   . GLU A 1 92  ? 67.528  122.311 121.737 1.00 107.94 ? 92  GLU A CB   1 
ATOM   1350 H H    . GLU A 1 92  ? 67.756  119.473 120.538 1.00 107.94 ? 92  GLU A H    1 
ATOM   1351 H HA   . GLU A 1 92  ? 67.552  120.385 122.426 1.00 107.94 ? 92  GLU A HA   1 
ATOM   1352 N N    . VAL A 1 93  ? 64.824  119.870 121.545 1.00 116.17 ? 93  VAL A N    1 
ATOM   1353 C CA   . VAL A 1 93  ? 63.461  119.620 121.990 1.00 116.17 ? 93  VAL A CA   1 
ATOM   1354 C C    . VAL A 1 93  ? 63.495  118.880 123.319 1.00 116.17 ? 93  VAL A C    1 
ATOM   1355 O O    . VAL A 1 93  ? 64.269  117.931 123.506 1.00 116.17 ? 93  VAL A O    1 
ATOM   1356 C CB   . VAL A 1 93  ? 62.696  118.826 120.917 1.00 116.17 ? 93  VAL A CB   1 
ATOM   1357 C CG1  . VAL A 1 93  ? 61.330  118.397 121.437 1.00 116.17 ? 93  VAL A CG1  1 
ATOM   1358 C CG2  . VAL A 1 93  ? 62.552  119.659 119.640 1.00 116.17 ? 93  VAL A CG2  1 
ATOM   1359 H H    . VAL A 1 93  ? 65.066  119.388 120.878 1.00 116.17 ? 93  VAL A H    1 
ATOM   1360 H HA   . VAL A 1 93  ? 63.006  120.465 122.127 1.00 116.17 ? 93  VAL A HA   1 
ATOM   1361 H HB   . VAL A 1 93  ? 63.203  118.027 120.700 1.00 116.17 ? 93  VAL A HB   1 
ATOM   1362 H HG11 . VAL A 1 93  ? 60.769  118.151 120.685 1.00 116.17 ? 93  VAL A HG11 1 
ATOM   1363 H HG12 . VAL A 1 93  ? 61.438  117.636 122.028 1.00 116.17 ? 93  VAL A HG12 1 
ATOM   1364 H HG13 . VAL A 1 93  ? 60.928  119.138 121.915 1.00 116.17 ? 93  VAL A HG13 1 
ATOM   1365 H HG21 . VAL A 1 93  ? 62.217  119.095 118.927 1.00 116.17 ? 93  VAL A HG21 1 
ATOM   1366 H HG22 . VAL A 1 93  ? 61.929  120.385 119.801 1.00 116.17 ? 93  VAL A HG22 1 
ATOM   1367 H HG23 . VAL A 1 93  ? 63.421  120.015 119.393 1.00 116.17 ? 93  VAL A HG23 1 
ATOM   1368 N N    . ASP A 1 94  ? 62.659  119.322 124.255 1.00 118.24 ? 94  ASP A N    1 
ATOM   1369 C CA   . ASP A 1 94  ? 62.655  118.750 125.595 1.00 118.24 ? 94  ASP A CA   1 
ATOM   1370 C C    . ASP A 1 94  ? 62.331  117.264 125.543 1.00 118.24 ? 94  ASP A C    1 
ATOM   1371 O O    . ASP A 1 94  ? 61.216  116.872 125.187 1.00 118.24 ? 94  ASP A O    1 
ATOM   1372 C CB   . ASP A 1 94  ? 61.641  119.485 126.472 1.00 118.24 ? 94  ASP A CB   1 
ATOM   1373 H H    . ASP A 1 94  ? 62.091  119.957 124.144 1.00 118.24 ? 94  ASP A H    1 
ATOM   1374 H HA   . ASP A 1 94  ? 63.535  118.856 125.990 1.00 118.24 ? 94  ASP A HA   1 
ATOM   1375 N N    . TRP A 1 95  ? 63.313  116.440 125.904 1.00 120.27 ? 95  TRP A N    1 
ATOM   1376 C CA   . TRP A 1 95  ? 63.120  115.005 126.043 1.00 120.27 ? 95  TRP A CA   1 
ATOM   1377 C C    . TRP A 1 95  ? 62.848  114.594 127.483 1.00 120.27 ? 95  TRP A C    1 
ATOM   1378 O O    . TRP A 1 95  ? 62.588  113.415 127.740 1.00 120.27 ? 95  TRP A O    1 
ATOM   1379 C CB   . TRP A 1 95  ? 64.351  114.253 125.526 1.00 120.27 ? 95  TRP A CB   1 
ATOM   1380 C CG   . TRP A 1 95  ? 65.070  114.948 124.402 1.00 120.27 ? 95  TRP A CG   1 
ATOM   1381 C CD1  . TRP A 1 95  ? 66.132  115.799 124.512 1.00 120.27 ? 95  TRP A CD1  1 
ATOM   1382 C CD2  . TRP A 1 95  ? 64.784  114.843 123.002 1.00 120.27 ? 95  TRP A CD2  1 
ATOM   1383 N NE1  . TRP A 1 95  ? 66.524  116.231 123.267 1.00 120.27 ? 95  TRP A NE1  1 
ATOM   1384 C CE2  . TRP A 1 95  ? 65.712  115.658 122.323 1.00 120.27 ? 95  TRP A CE2  1 
ATOM   1385 C CE3  . TRP A 1 95  ? 63.833  114.141 122.256 1.00 120.27 ? 95  TRP A CE3  1 
ATOM   1386 C CZ2  . TRP A 1 95  ? 65.715  115.790 120.936 1.00 120.27 ? 95  TRP A CZ2  1 
ATOM   1387 C CZ3  . TRP A 1 95  ? 63.839  114.273 120.880 1.00 120.27 ? 95  TRP A CZ3  1 
ATOM   1388 C CH2  . TRP A 1 95  ? 64.773  115.091 120.235 1.00 120.27 ? 95  TRP A CH2  1 
ATOM   1389 H H    . TRP A 1 95  ? 64.117  116.696 126.069 1.00 120.27 ? 95  TRP A H    1 
ATOM   1390 H HA   . TRP A 1 95  ? 62.360  114.738 125.505 1.00 120.27 ? 95  TRP A HA   1 
ATOM   1391 H HB2  . TRP A 1 95  ? 64.977  114.150 126.256 1.00 120.27 ? 95  TRP A HB2  1 
ATOM   1392 H HB3  . TRP A 1 95  ? 64.074  113.380 125.211 1.00 120.27 ? 95  TRP A HB3  1 
ATOM   1393 H HD1  . TRP A 1 95  ? 66.533  116.049 125.313 1.00 120.27 ? 95  TRP A HD1  1 
ATOM   1394 H HE1  . TRP A 1 95  ? 67.172  116.772 123.104 1.00 120.27 ? 95  TRP A HE1  1 
ATOM   1395 H HE3  . TRP A 1 95  ? 63.209  113.595 122.677 1.00 120.27 ? 95  TRP A HE3  1 
ATOM   1396 H HZ2  . TRP A 1 95  ? 66.334  116.333 120.503 1.00 120.27 ? 95  TRP A HZ2  1 
ATOM   1397 H HZ3  . TRP A 1 95  ? 63.211  113.810 120.374 1.00 120.27 ? 95  TRP A HZ3  1 
ATOM   1398 H HH2  . TRP A 1 95  ? 64.753  115.160 119.308 1.00 120.27 ? 95  TRP A HH2  1 
ATOM   1399 N N    . ASN A 1 96  ? 62.899  115.533 128.421 1.00 125.16 ? 96  ASN A N    1 
ATOM   1400 C CA   . ASN A 1 96  ? 62.654  115.265 129.829 1.00 125.16 ? 96  ASN A CA   1 
ATOM   1401 C C    . ASN A 1 96  ? 61.288  115.810 130.215 1.00 125.16 ? 96  ASN A C    1 
ATOM   1402 O O    . ASN A 1 96  ? 60.879  116.873 129.741 1.00 125.16 ? 96  ASN A O    1 
ATOM   1403 C CB   . ASN A 1 96  ? 63.729  115.905 130.708 1.00 125.16 ? 96  ASN A CB   1 
ATOM   1404 C CG   . ASN A 1 96  ? 63.763  117.413 130.578 1.00 125.16 ? 96  ASN A CG   1 
ATOM   1405 O OD1  . ASN A 1 96  ? 64.404  117.957 129.678 1.00 125.16 ? 96  ASN A OD1  1 
ATOM   1406 N ND2  . ASN A 1 96  ? 63.069  118.099 131.478 1.00 125.16 ? 96  ASN A ND2  1 
ATOM   1407 H H    . ASN A 1 96  ? 63.081  116.359 128.258 1.00 125.16 ? 96  ASN A H    1 
ATOM   1408 H HA   . ASN A 1 96  ? 62.655  114.307 129.986 1.00 125.16 ? 96  ASN A HA   1 
ATOM   1409 H HB2  . ASN A 1 96  ? 63.549  115.687 131.633 1.00 125.16 ? 96  ASN A HB2  1 
ATOM   1410 H HB3  . ASN A 1 96  ? 64.594  115.558 130.445 1.00 125.16 ? 96  ASN A HB3  1 
ATOM   1411 H HD21 . ASN A 1 96  ? 62.633  117.685 132.092 1.00 125.16 ? 96  ASN A HD21 1 
ATOM   1412 H HD22 . ASN A 1 96  ? 63.051  118.957 131.444 1.00 125.16 ? 96  ASN A HD22 1 
ATOM   1413 N N    . GLN A 1 97  ? 60.595  115.084 131.090 1.00 131.24 ? 97  GLN A N    1 
ATOM   1414 C CA   . GLN A 1 97  ? 59.239  115.446 131.491 1.00 131.24 ? 97  GLN A CA   1 
ATOM   1415 C C    . GLN A 1 97  ? 58.323  115.540 130.275 1.00 131.24 ? 97  GLN A C    1 
ATOM   1416 O O    . GLN A 1 97  ? 57.431  116.388 130.202 1.00 131.24 ? 97  GLN A O    1 
ATOM   1417 C CB   . GLN A 1 97  ? 59.232  116.758 132.276 1.00 131.24 ? 97  GLN A CB   1 
ATOM   1418 H H    . GLN A 1 97  ? 60.894  114.373 131.473 1.00 131.24 ? 97  GLN A H    1 
ATOM   1419 H HA   . GLN A 1 97  ? 58.892  114.753 132.074 1.00 131.24 ? 97  GLN A HA   1 
ATOM   1420 N N    . SER A 1 98  ? 58.553  114.658 129.299 1.00 135.07 ? 98  SER A N    1 
ATOM   1421 C CA   . SER A 1 98  ? 57.702  114.562 128.108 1.00 135.07 ? 98  SER A CA   1 
ATOM   1422 C C    . SER A 1 98  ? 57.569  113.078 127.774 1.00 135.07 ? 98  SER A C    1 
ATOM   1423 O O    . SER A 1 98  ? 58.388  112.519 127.041 1.00 135.07 ? 98  SER A O    1 
ATOM   1424 C CB   . SER A 1 98  ? 58.281  115.358 126.945 1.00 135.07 ? 98  SER A CB   1 
ATOM   1425 O OG   . SER A 1 98  ? 59.526  114.825 126.533 1.00 135.07 ? 98  SER A OG   1 
ATOM   1426 H H    . SER A 1 98  ? 59.205  114.093 129.307 1.00 135.07 ? 98  SER A H    1 
ATOM   1427 H HA   . SER A 1 98  ? 56.821  114.913 128.311 1.00 135.07 ? 98  SER A HA   1 
ATOM   1428 N N    . ALA A 1 99  ? 56.523  112.450 128.312 1.00 135.75 ? 99  ALA A N    1 
ATOM   1429 C CA   . ALA A 1 99  ? 56.301  111.015 128.138 1.00 135.75 ? 99  ALA A CA   1 
ATOM   1430 C C    . ALA A 1 99  ? 55.439  110.804 126.898 1.00 135.75 ? 99  ALA A C    1 
ATOM   1431 O O    . ALA A 1 99  ? 54.214  110.678 126.956 1.00 135.75 ? 99  ALA A O    1 
ATOM   1432 C CB   . ALA A 1 99  ? 55.669  110.413 129.389 1.00 135.75 ? 99  ALA A CB   1 
ATOM   1433 H H    . ALA A 1 99  ? 55.918  112.839 128.784 1.00 135.75 ? 99  ALA A H    1 
ATOM   1434 H HA   . ALA A 1 99  ? 57.151  110.571 127.989 1.00 135.75 ? 99  ALA A HA   1 
ATOM   1435 H HB1  . ALA A 1 99  ? 54.820  110.848 129.561 1.00 135.75 ? 99  ALA A HB1  1 
ATOM   1436 H HB2  . ALA A 1 99  ? 56.269  110.552 130.139 1.00 135.75 ? 99  ALA A HB2  1 
ATOM   1437 H HB3  . ALA A 1 99  ? 55.536  109.464 129.246 1.00 135.75 ? 99  ALA A HB3  1 
ATOM   1438 N N    . LEU A 1 100 ? 56.112  110.770 125.748 1.00 137.20 ? 100 LEU A N    1 
ATOM   1439 C CA   . LEU A 1 100 ? 55.484  110.547 124.454 1.00 137.20 ? 100 LEU A CA   1 
ATOM   1440 C C    . LEU A 1 100 ? 55.633  109.104 123.979 1.00 137.20 ? 100 LEU A C    1 
ATOM   1441 O O    . LEU A 1 100 ? 55.377  108.815 122.805 1.00 137.20 ? 100 LEU A O    1 
ATOM   1442 C CB   . LEU A 1 100 ? 56.076  111.511 123.425 1.00 137.20 ? 100 LEU A CB   1 
ATOM   1443 C CG   . LEU A 1 100 ? 55.821  112.993 123.722 1.00 137.20 ? 100 LEU A CG   1 
ATOM   1444 C CD1  . LEU A 1 100 ? 56.813  113.888 123.002 1.00 137.20 ? 100 LEU A CD1  1 
ATOM   1445 C CD2  . LEU A 1 100 ? 54.401  113.371 123.340 1.00 137.20 ? 100 LEU A CD2  1 
ATOM   1446 H H    . LEU A 1 100 ? 56.961  110.884 125.693 1.00 137.20 ? 100 LEU A H    1 
ATOM   1447 H HA   . LEU A 1 100 ? 54.536  110.739 124.521 1.00 137.20 ? 100 LEU A HA   1 
ATOM   1448 N N    . SER A 1 101 ? 56.061  108.200 124.862 1.00 138.14 ? 101 SER A N    1 
ATOM   1449 C CA   . SER A 1 101 ? 56.168  106.780 124.542 1.00 138.14 ? 101 SER A CA   1 
ATOM   1450 C C    . SER A 1 101 ? 57.360  106.506 123.632 1.00 138.14 ? 101 SER A C    1 
ATOM   1451 O O    . SER A 1 101 ? 57.771  107.373 122.853 1.00 138.14 ? 101 SER A O    1 
ATOM   1452 C CB   . SER A 1 101 ? 54.879  106.275 123.890 1.00 138.14 ? 101 SER A CB   1 
ATOM   1453 H H    . SER A 1 101 ? 56.293  108.390 125.669 1.00 138.14 ? 101 SER A H    1 
ATOM   1454 H HA   . SER A 1 101 ? 56.302  106.283 125.366 1.00 138.14 ? 101 SER A HA   1 
ATOM   1455 N N    . CYS A 1 102 ? 57.914  105.294 123.719 1.00 136.13 ? 102 CYS A N    1 
ATOM   1456 C CA   . CYS A 1 102 ? 59.063  104.935 122.893 1.00 136.13 ? 102 CYS A CA   1 
ATOM   1457 C C    . CYS A 1 102 ? 58.712  104.944 121.406 1.00 136.13 ? 102 CYS A C    1 
ATOM   1458 O O    . CYS A 1 102 ? 59.565  105.246 120.563 1.00 136.13 ? 102 CYS A O    1 
ATOM   1459 C CB   . CYS A 1 102 ? 59.582  103.557 123.312 1.00 136.13 ? 102 CYS A CB   1 
ATOM   1460 S SG   . CYS A 1 102 ? 61.376  103.394 123.525 1.00 136.13 ? 102 CYS A SG   1 
ATOM   1461 H H    . CYS A 1 102 ? 57.657  104.672 124.256 1.00 136.13 ? 102 CYS A H    1 
ATOM   1462 H HA   . CYS A 1 102 ? 59.764  105.590 123.035 1.00 136.13 ? 102 CYS A HA   1 
ATOM   1463 N N    . VAL A 1 103 ? 57.471  104.590 121.063 1.00 137.08 ? 103 VAL A N    1 
ATOM   1464 C CA   . VAL A 1 103 ? 57.084  104.496 119.656 1.00 137.08 ? 103 VAL A CA   1 
ATOM   1465 C C    . VAL A 1 103 ? 57.156  105.862 118.983 1.00 137.08 ? 103 VAL A C    1 
ATOM   1466 O O    . VAL A 1 103 ? 57.673  105.995 117.866 1.00 137.08 ? 103 VAL A O    1 
ATOM   1467 C CB   . VAL A 1 103 ? 55.675  103.885 119.532 1.00 137.08 ? 103 VAL A CB   1 
ATOM   1468 C CG1  . VAL A 1 103 ? 54.644  104.801 120.175 1.00 137.08 ? 103 VAL A CG1  1 
ATOM   1469 C CG2  . VAL A 1 103 ? 55.326  103.627 118.067 1.00 137.08 ? 103 VAL A CG2  1 
ATOM   1470 H H    . VAL A 1 103 ? 56.842  104.406 121.617 1.00 137.08 ? 103 VAL A H    1 
ATOM   1471 H HA   . VAL A 1 103 ? 57.703  103.903 119.198 1.00 137.08 ? 103 VAL A HA   1 
ATOM   1472 H HB   . VAL A 1 103 ? 55.655  103.037 120.003 1.00 137.08 ? 103 VAL A HB   1 
ATOM   1473 H HG11 . VAL A 1 103 ? 53.823  104.307 120.318 1.00 137.08 ? 103 VAL A HG11 1 
ATOM   1474 H HG12 . VAL A 1 103 ? 54.992  105.117 121.024 1.00 137.08 ? 103 VAL A HG12 1 
ATOM   1475 H HG13 . VAL A 1 103 ? 54.480  105.554 119.587 1.00 137.08 ? 103 VAL A HG13 1 
ATOM   1476 H HG21 . VAL A 1 103 ? 54.487  103.143 118.022 1.00 137.08 ? 103 VAL A HG21 1 
ATOM   1477 H HG22 . VAL A 1 103 ? 55.240  104.476 117.604 1.00 137.08 ? 103 VAL A HG22 1 
ATOM   1478 H HG23 . VAL A 1 103 ? 56.033  103.101 117.662 1.00 137.08 ? 103 VAL A HG23 1 
ATOM   1479 N N    . ASP A 1 104 ? 56.652  106.897 119.652 1.00 135.89 ? 104 ASP A N    1 
ATOM   1480 C CA   . ASP A 1 104 ? 56.500  108.232 119.074 1.00 135.89 ? 104 ASP A CA   1 
ATOM   1481 C C    . ASP A 1 104 ? 57.119  109.251 120.020 1.00 135.89 ? 104 ASP A C    1 
ATOM   1482 O O    . ASP A 1 104 ? 56.412  110.052 120.643 1.00 135.89 ? 104 ASP A O    1 
ATOM   1483 C CB   . ASP A 1 104 ? 55.025  108.548 118.819 1.00 135.89 ? 104 ASP A CB   1 
ATOM   1484 C CG   . ASP A 1 104 ? 54.407  107.645 117.770 1.00 135.89 ? 104 ASP A CG   1 
ATOM   1485 O OD1  . ASP A 1 104 ? 55.140  107.197 116.864 1.00 135.89 ? 104 ASP A OD1  1 
ATOM   1486 O OD2  . ASP A 1 104 ? 53.187  107.385 117.850 1.00 135.89 ? 104 ASP A OD2  1 
ATOM   1487 H H    . ASP A 1 104 ? 56.376  106.852 120.467 1.00 135.89 ? 104 ASP A H    1 
ATOM   1488 H HA   . ASP A 1 104 ? 56.964  108.278 118.224 1.00 135.89 ? 104 ASP A HA   1 
ATOM   1489 H HB2  . ASP A 1 104 ? 54.527  108.430 119.645 1.00 135.89 ? 104 ASP A HB2  1 
ATOM   1490 H HB3  . ASP A 1 104 ? 54.942  109.463 118.510 1.00 135.89 ? 104 ASP A HB3  1 
ATOM   1491 N N    . PRO A 1 105 ? 58.446  109.237 120.167 1.00 134.16 ? 105 PRO A N    1 
ATOM   1492 C CA   . PRO A 1 105 ? 59.088  110.196 121.075 1.00 134.16 ? 105 PRO A CA   1 
ATOM   1493 C C    . PRO A 1 105 ? 59.009  111.634 120.586 1.00 134.16 ? 105 PRO A C    1 
ATOM   1494 O O    . PRO A 1 105 ? 58.633  112.533 121.345 1.00 134.16 ? 105 PRO A O    1 
ATOM   1495 C CB   . PRO A 1 105 ? 60.539  109.706 121.128 1.00 134.16 ? 105 PRO A CB   1 
ATOM   1496 C CG   . PRO A 1 105 ? 60.740  109.033 119.828 1.00 134.16 ? 105 PRO A CG   1 
ATOM   1497 C CD   . PRO A 1 105 ? 59.434  108.342 119.543 1.00 134.16 ? 105 PRO A CD   1 
ATOM   1498 H HA   . PRO A 1 105 ? 58.694  110.123 121.957 1.00 134.16 ? 105 PRO A HA   1 
ATOM   1499 H HB2  . PRO A 1 105 ? 61.138  110.463 121.229 1.00 134.16 ? 105 PRO A HB2  1 
ATOM   1500 H HB3  . PRO A 1 105 ? 60.646  109.079 121.860 1.00 134.16 ? 105 PRO A HB3  1 
ATOM   1501 H HG2  . PRO A 1 105 ? 60.925  109.701 119.150 1.00 134.16 ? 105 PRO A HG2  1 
ATOM   1502 H HG3  . PRO A 1 105 ? 61.469  108.398 119.898 1.00 134.16 ? 105 PRO A HG3  1 
ATOM   1503 H HD2  . PRO A 1 105 ? 59.283  108.273 118.589 1.00 134.16 ? 105 PRO A HD2  1 
ATOM   1504 H HD3  . PRO A 1 105 ? 59.414  107.475 119.975 1.00 134.16 ? 105 PRO A HD3  1 
ATOM   1505 N N    . LEU A 1 106 ? 59.379  111.863 119.323 1.00 130.52 ? 106 LEU A N    1 
ATOM   1506 C CA   . LEU A 1 106 ? 59.456  113.207 118.766 1.00 130.52 ? 106 LEU A CA   1 
ATOM   1507 C C    . LEU A 1 106 ? 58.634  113.405 117.500 1.00 130.52 ? 106 LEU A C    1 
ATOM   1508 O O    . LEU A 1 106 ? 58.548  114.539 117.016 1.00 130.52 ? 106 LEU A O    1 
ATOM   1509 C CB   . LEU A 1 106 ? 60.919  113.578 118.463 1.00 130.52 ? 106 LEU A CB   1 
ATOM   1510 C CG   . LEU A 1 106 ? 61.490  113.178 117.098 1.00 130.52 ? 106 LEU A CG   1 
ATOM   1511 C CD1  . LEU A 1 106 ? 62.911  113.704 116.940 1.00 130.52 ? 106 LEU A CD1  1 
ATOM   1512 C CD2  . LEU A 1 106 ? 61.443  111.672 116.891 1.00 130.52 ? 106 LEU A CD2  1 
ATOM   1513 H H    . LEU A 1 106 ? 59.590  111.241 118.769 1.00 130.52 ? 106 LEU A H    1 
ATOM   1514 H HA   . LEU A 1 106 ? 59.130  113.838 119.425 1.00 130.52 ? 106 LEU A HA   1 
ATOM   1515 H HB2  . LEU A 1 106 ? 61.004  114.541 118.529 1.00 130.52 ? 106 LEU A HB2  1 
ATOM   1516 H HB3  . LEU A 1 106 ? 61.482  113.163 119.135 1.00 130.52 ? 106 LEU A HB3  1 
ATOM   1517 H HG   . LEU A 1 106 ? 60.957  113.589 116.401 1.00 130.52 ? 106 LEU A HG   1 
ATOM   1518 H HD11 . LEU A 1 106 ? 63.305  113.319 116.141 1.00 130.52 ? 106 LEU A HD11 1 
ATOM   1519 H HD12 . LEU A 1 106 ? 62.880  114.670 116.860 1.00 130.52 ? 106 LEU A HD12 1 
ATOM   1520 H HD13 . LEU A 1 106 ? 63.432  113.451 117.718 1.00 130.52 ? 106 LEU A HD13 1 
ATOM   1521 H HD21 . LEU A 1 106 ? 61.940  111.449 116.089 1.00 130.52 ? 106 LEU A HD21 1 
ATOM   1522 H HD22 . LEU A 1 106 ? 60.519  111.397 116.789 1.00 130.52 ? 106 LEU A HD22 1 
ATOM   1523 H HD23 . LEU A 1 106 ? 61.840  111.232 117.660 1.00 130.52 ? 106 LEU A HD23 1 
ATOM   1524 N N    . ALA A 1 107 ? 58.048  112.347 116.939 1.00 134.16 ? 107 ALA A N    1 
ATOM   1525 C CA   . ALA A 1 107 ? 57.339  112.486 115.671 1.00 134.16 ? 107 ALA A CA   1 
ATOM   1526 C C    . ALA A 1 107 ? 56.165  113.453 115.783 1.00 134.16 ? 107 ALA A C    1 
ATOM   1527 O O    . ALA A 1 107 ? 55.948  114.282 114.891 1.00 134.16 ? 107 ALA A O    1 
ATOM   1528 C CB   . ALA A 1 107 ? 56.858  111.118 115.189 1.00 134.16 ? 107 ALA A CB   1 
ATOM   1529 H H    . ALA A 1 107 ? 58.054  111.550 117.264 1.00 134.16 ? 107 ALA A H    1 
ATOM   1530 H HA   . ALA A 1 107 ? 57.953  112.843 115.009 1.00 134.16 ? 107 ALA A HA   1 
ATOM   1531 H HB1  . ALA A 1 107 ? 56.444  111.220 114.317 1.00 134.16 ? 107 ALA A HB1  1 
ATOM   1532 H HB2  . ALA A 1 107 ? 57.619  110.518 115.129 1.00 134.16 ? 107 ALA A HB2  1 
ATOM   1533 H HB3  . ALA A 1 107 ? 56.215  110.766 115.824 1.00 134.16 ? 107 ALA A HB3  1 
ATOM   1534 N N    . SER A 1 108 ? 55.401  113.368 116.874 1.00 136.39 ? 108 SER A N    1 
ATOM   1535 C CA   . SER A 1 108 ? 54.108  114.043 116.927 1.00 136.39 ? 108 SER A CA   1 
ATOM   1536 C C    . SER A 1 108 ? 54.253  115.561 116.907 1.00 136.39 ? 108 SER A C    1 
ATOM   1537 O O    . SER A 1 108 ? 53.423  116.261 116.315 1.00 136.39 ? 108 SER A O    1 
ATOM   1538 C CB   . SER A 1 108 ? 53.340  113.602 118.171 1.00 136.39 ? 108 SER A CB   1 
ATOM   1539 O OG   . SER A 1 108 ? 54.037  113.953 119.352 1.00 136.39 ? 108 SER A OG   1 
ATOM   1540 H H    . SER A 1 108 ? 55.609  112.941 117.591 1.00 136.39 ? 108 SER A H    1 
ATOM   1541 H HA   . SER A 1 108 ? 53.590  113.785 116.150 1.00 136.39 ? 108 SER A HA   1 
ATOM   1542 H HB2  . SER A 1 108 ? 52.469  114.031 118.173 1.00 136.39 ? 108 SER A HB2  1 
ATOM   1543 H HB3  . SER A 1 108 ? 53.235  112.639 118.146 1.00 136.39 ? 108 SER A HB3  1 
ATOM   1544 H HG   . SER A 1 108 ? 54.731  113.486 119.421 1.00 136.39 ? 108 SER A HG   1 
ATOM   1545 N N    . LEU A 1 109 ? 55.289  116.092 117.560 1.00 133.06 ? 109 LEU A N    1 
ATOM   1546 C CA   . LEU A 1 109 ? 55.343  117.533 117.790 1.00 133.06 ? 109 LEU A CA   1 
ATOM   1547 C C    . LEU A 1 109 ? 55.355  118.311 116.480 1.00 133.06 ? 109 LEU A C    1 
ATOM   1548 O O    . LEU A 1 109 ? 54.569  119.248 116.300 1.00 133.06 ? 109 LEU A O    1 
ATOM   1549 C CB   . LEU A 1 109 ? 56.573  117.884 118.628 1.00 133.06 ? 109 LEU A CB   1 
ATOM   1550 C CG   . LEU A 1 109 ? 56.521  117.657 120.143 1.00 133.06 ? 109 LEU A CG   1 
ATOM   1551 C CD1  . LEU A 1 109 ? 55.422  118.483 120.795 1.00 133.06 ? 109 LEU A CD1  1 
ATOM   1552 C CD2  . LEU A 1 109 ? 56.342  116.185 120.466 1.00 133.06 ? 109 LEU A CD2  1 
ATOM   1553 H H    . LEU A 1 109 ? 55.966  115.653 117.858 1.00 133.06 ? 109 LEU A H    1 
ATOM   1554 H HA   . LEU A 1 109 ? 54.553  117.805 118.282 1.00 133.06 ? 109 LEU A HA   1 
ATOM   1555 H HB2  . LEU A 1 109 ? 57.315  117.358 118.291 1.00 133.06 ? 109 LEU A HB2  1 
ATOM   1556 H HB3  . LEU A 1 109 ? 56.762  118.826 118.496 1.00 133.06 ? 109 LEU A HB3  1 
ATOM   1557 H HG   . LEU A 1 109 ? 57.366  117.941 120.526 1.00 133.06 ? 109 LEU A HG   1 
ATOM   1558 H HD11 . LEU A 1 109 ? 55.543  118.456 121.757 1.00 133.06 ? 109 LEU A HD11 1 
ATOM   1559 H HD12 . LEU A 1 109 ? 55.482  119.398 120.480 1.00 133.06 ? 109 LEU A HD12 1 
ATOM   1560 H HD13 . LEU A 1 109 ? 54.560  118.107 120.561 1.00 133.06 ? 109 LEU A HD13 1 
ATOM   1561 H HD21 . LEU A 1 109 ? 56.395  116.064 121.427 1.00 133.06 ? 109 LEU A HD21 1 
ATOM   1562 H HD22 . LEU A 1 109 ? 55.474  115.894 120.145 1.00 133.06 ? 109 LEU A HD22 1 
ATOM   1563 H HD23 . LEU A 1 109 ? 57.047  115.684 120.029 1.00 133.06 ? 109 LEU A HD23 1 
ATOM   1564 N N    . ALA A 1 110 ? 56.219  117.922 115.541 1.00 133.87 ? 110 ALA A N    1 
ATOM   1565 C CA   . ALA A 1 110 ? 56.460  118.719 114.347 1.00 133.87 ? 110 ALA A CA   1 
ATOM   1566 C C    . ALA A 1 110 ? 55.835  118.154 113.082 1.00 133.87 ? 110 ALA A C    1 
ATOM   1567 O O    . ALA A 1 110 ? 55.631  118.910 112.128 1.00 133.87 ? 110 ALA A O    1 
ATOM   1568 C CB   . ALA A 1 110 ? 57.972  118.876 114.116 1.00 133.87 ? 110 ALA A CB   1 
ATOM   1569 H H    . ALA A 1 110 ? 56.679  117.196 115.574 1.00 133.87 ? 110 ALA A H    1 
ATOM   1570 H HA   . ALA A 1 110 ? 56.091  119.605 114.486 1.00 133.87 ? 110 ALA A HA   1 
ATOM   1571 H HB1  . ALA A 1 110 ? 58.116  119.409 113.319 1.00 133.87 ? 110 ALA A HB1  1 
ATOM   1572 H HB2  . ALA A 1 110 ? 58.365  119.315 114.886 1.00 133.87 ? 110 ALA A HB2  1 
ATOM   1573 H HB3  . ALA A 1 110 ? 58.364  117.995 114.002 1.00 133.87 ? 110 ALA A HB3  1 
ATOM   1574 N N    . ALA A 1 111 ? 55.532  116.857 113.046 1.00 131.33 ? 111 ALA A N    1 
ATOM   1575 C CA   . ALA A 1 111 ? 55.093  116.191 111.821 1.00 131.33 ? 111 ALA A CA   1 
ATOM   1576 C C    . ALA A 1 111 ? 56.145  116.302 110.723 1.00 131.33 ? 111 ALA A C    1 
ATOM   1577 O O    . ALA A 1 111 ? 55.856  116.071 109.546 1.00 131.33 ? 111 ALA A O    1 
ATOM   1578 C CB   . ALA A 1 111 ? 53.756  116.753 111.327 1.00 131.33 ? 111 ALA A CB   1 
ATOM   1579 H H    . ALA A 1 111 ? 55.571  116.333 113.727 1.00 131.33 ? 111 ALA A H    1 
ATOM   1580 H HA   . ALA A 1 111 ? 54.962  115.247 112.007 1.00 131.33 ? 111 ALA A HA   1 
ATOM   1581 H HB1  . ALA A 1 111 ? 53.481  116.259 110.539 1.00 131.33 ? 111 ALA A HB1  1 
ATOM   1582 H HB2  . ALA A 1 111 ? 53.094  116.658 112.029 1.00 131.33 ? 111 ALA A HB2  1 
ATOM   1583 H HB3  . ALA A 1 111 ? 53.867  117.690 111.103 1.00 131.33 ? 111 ALA A HB3  1 
ATOM   1584 N N    . ASN A 1 112 ? 57.377  116.649 111.100 1.00 132.32 ? 112 ASN A N    1 
ATOM   1585 C CA   . ASN A 1 112 ? 58.482  116.735 110.155 1.00 132.32 ? 112 ASN A CA   1 
ATOM   1586 C C    . ASN A 1 112 ? 59.782  116.997 110.905 1.00 132.32 ? 112 ASN A C    1 
ATOM   1587 O O    . ASN A 1 112 ? 59.766  117.537 112.016 1.00 132.32 ? 112 ASN A O    1 
ATOM   1588 C CB   . ASN A 1 112 ? 58.228  117.829 109.114 1.00 132.32 ? 112 ASN A CB   1 
ATOM   1589 C CG   . ASN A 1 112 ? 59.207  117.767 107.958 1.00 132.32 ? 112 ASN A CG   1 
ATOM   1590 O OD1  . ASN A 1 112 ? 60.330  117.286 108.108 1.00 132.32 ? 112 ASN A OD1  1 
ATOM   1591 N ND2  . ASN A 1 112 ? 58.785  118.249 106.797 1.00 132.32 ? 112 ASN A ND2  1 
ATOM   1592 H H    . ASN A 1 112 ? 57.600  116.845 111.907 1.00 132.32 ? 112 ASN A H    1 
ATOM   1593 H HA   . ASN A 1 112 ? 58.571  115.888 109.691 1.00 132.32 ? 112 ASN A HA   1 
ATOM   1594 H HB2  . ASN A 1 112 ? 57.337  117.726 108.746 1.00 132.32 ? 112 ASN A HB2  1 
ATOM   1595 H HB3  . ASN A 1 112 ? 58.314  118.697 109.537 1.00 132.32 ? 112 ASN A HB3  1 
ATOM   1596 H HD21 . ASN A 1 112 ? 59.300  118.238 106.111 1.00 132.32 ? 112 ASN A HD21 1 
ATOM   1597 H HD22 . ASN A 1 112 ? 57.995  118.574 106.732 1.00 132.32 ? 112 ASN A HD22 1 
ATOM   1598 N N    . ARG A 1 113 ? 60.910  116.620 110.305 1.00 132.07 ? 113 ARG A N    1 
ATOM   1599 C CA   . ARG A 1 113 ? 62.196  116.653 110.994 1.00 132.07 ? 113 ARG A CA   1 
ATOM   1600 C C    . ARG A 1 113 ? 62.975  117.931 110.687 1.00 132.07 ? 113 ARG A C    1 
ATOM   1601 O O    . ARG A 1 113 ? 63.302  118.699 111.597 1.00 132.07 ? 113 ARG A O    1 
ATOM   1602 C CB   . ARG A 1 113 ? 63.012  115.413 110.609 1.00 132.07 ? 113 ARG A CB   1 
ATOM   1603 C CG   . ARG A 1 113 ? 64.055  115.016 111.636 1.00 132.07 ? 113 ARG A CG   1 
ATOM   1604 C CD   . ARG A 1 113 ? 64.509  113.580 111.436 1.00 132.07 ? 113 ARG A CD   1 
ATOM   1605 N NE   . ARG A 1 113 ? 63.373  112.685 111.257 1.00 132.07 ? 113 ARG A NE   1 
ATOM   1606 C CZ   . ARG A 1 113 ? 62.640  112.193 112.246 1.00 132.07 ? 113 ARG A CZ   1 
ATOM   1607 N NH1  . ARG A 1 113 ? 62.904  112.479 113.510 1.00 132.07 ? 113 ARG A NH1  1 
ATOM   1608 N NH2  . ARG A 1 113 ? 61.615  111.396 111.960 1.00 132.07 ? 113 ARG A NH2  1 
ATOM   1609 H H    . ARG A 1 113 ? 60.959  116.343 109.493 1.00 132.07 ? 113 ARG A H    1 
ATOM   1610 H HA   . ARG A 1 113 ? 62.042  116.621 111.950 1.00 132.07 ? 113 ARG A HA   1 
ATOM   1611 N N    . SER A 1 114 ? 63.271  118.174 109.406 1.00 130.14 ? 114 SER A N    1 
ATOM   1612 C CA   . SER A 1 114 ? 64.131  119.297 109.043 1.00 130.14 ? 114 SER A CA   1 
ATOM   1613 C C    . SER A 1 114 ? 63.579  120.619 109.561 1.00 130.14 ? 114 SER A C    1 
ATOM   1614 O O    . SER A 1 114 ? 64.334  121.475 110.034 1.00 130.14 ? 114 SER A O    1 
ATOM   1615 C CB   . SER A 1 114 ? 64.304  119.355 107.526 1.00 130.14 ? 114 SER A CB   1 
ATOM   1616 O OG   . SER A 1 114 ? 65.117  120.452 107.152 1.00 130.14 ? 114 SER A OG   1 
ATOM   1617 H H    . SER A 1 114 ? 62.992  117.708 108.741 1.00 130.14 ? 114 SER A H    1 
ATOM   1618 H HA   . SER A 1 114 ? 65.004  119.159 109.441 1.00 130.14 ? 114 SER A HA   1 
ATOM   1619 H HB2  . SER A 1 114 ? 64.733  118.538 107.227 1.00 130.14 ? 114 SER A HB2  1 
ATOM   1620 H HB3  . SER A 1 114 ? 63.435  119.448 107.105 1.00 130.14 ? 114 SER A HB3  1 
ATOM   1621 H HG   . SER A 1 114 ? 65.916  120.296 107.350 1.00 130.14 ? 114 SER A HG   1 
ATOM   1622 N N    . HIS A 1 115 ? 62.260  120.805 109.482 1.00 132.04 ? 115 HIS A N    1 
ATOM   1623 C CA   . HIS A 1 115 ? 61.656  122.048 109.945 1.00 132.04 ? 115 HIS A CA   1 
ATOM   1624 C C    . HIS A 1 115 ? 61.806  122.226 111.447 1.00 132.04 ? 115 HIS A C    1 
ATOM   1625 O O    . HIS A 1 115 ? 61.609  123.335 111.953 1.00 132.04 ? 115 HIS A O    1 
ATOM   1626 C CB   . HIS A 1 115 ? 60.175  122.094 109.567 1.00 132.04 ? 115 HIS A CB   1 
ATOM   1627 C CG   . HIS A 1 115 ? 59.925  122.064 108.091 1.00 132.04 ? 115 HIS A CG   1 
ATOM   1628 N ND1  . HIS A 1 115 ? 60.358  121.035 107.282 1.00 132.04 ? 115 HIS A ND1  1 
ATOM   1629 C CD2  . HIS A 1 115 ? 59.280  122.934 107.278 1.00 132.04 ? 115 HIS A CD2  1 
ATOM   1630 C CE1  . HIS A 1 115 ? 59.994  121.273 106.035 1.00 132.04 ? 115 HIS A CE1  1 
ATOM   1631 N NE2  . HIS A 1 115 ? 59.339  122.419 106.005 1.00 132.04 ? 115 HIS A NE2  1 
ATOM   1632 H H    . HIS A 1 115 ? 61.699  120.224 109.188 1.00 132.04 ? 115 HIS A H    1 
ATOM   1633 H HA   . HIS A 1 115 ? 62.100  122.795 109.514 1.00 132.04 ? 115 HIS A HA   1 
ATOM   1634 H HB2  . HIS A 1 115 ? 59.730  121.329 109.959 1.00 132.04 ? 115 HIS A HB2  1 
ATOM   1635 H HB3  . HIS A 1 115 ? 59.790  122.913 109.917 1.00 132.04 ? 115 HIS A HB3  1 
ATOM   1636 H HD1  . HIS A 1 115 ? 60.798  120.345 107.547 1.00 132.04 ? 115 HIS A HD1  1 
ATOM   1637 H HD2  . HIS A 1 115 ? 58.874  123.731 107.530 1.00 132.04 ? 115 HIS A HD2  1 
ATOM   1638 H HE1  . HIS A 1 115 ? 60.169  120.727 105.304 1.00 132.04 ? 115 HIS A HE1  1 
ATOM   1639 N N    . LEU A 1 116 ? 62.142  121.163 112.172 1.00 124.00 ? 116 LEU A N    1 
ATOM   1640 C CA   . LEU A 1 116 ? 62.238  121.257 113.622 1.00 124.00 ? 116 LEU A CA   1 
ATOM   1641 C C    . LEU A 1 116 ? 63.276  122.314 113.986 1.00 124.00 ? 116 LEU A C    1 
ATOM   1642 O O    . LEU A 1 116 ? 64.104  122.692 113.146 1.00 124.00 ? 116 LEU A O    1 
ATOM   1643 C CB   . LEU A 1 116 ? 62.601  119.900 114.227 1.00 124.00 ? 116 LEU A CB   1 
ATOM   1644 H H    . LEU A 1 116 ? 62.323  120.388 111.847 1.00 124.00 ? 116 LEU A H    1 
ATOM   1645 H HA   . LEU A 1 116 ? 61.381  121.521 113.985 1.00 124.00 ? 116 LEU A HA   1 
ATOM   1646 N N    . PRO A 1 117 ? 63.269  122.813 115.223 1.00 115.55 ? 117 PRO A N    1 
ATOM   1647 C CA   . PRO A 1 117 ? 64.172  123.915 115.586 1.00 115.55 ? 117 PRO A CA   1 
ATOM   1648 C C    . PRO A 1 117 ? 65.539  123.393 116.006 1.00 115.55 ? 117 PRO A C    1 
ATOM   1649 O O    . PRO A 1 117 ? 65.644  122.501 116.850 1.00 115.55 ? 117 PRO A O    1 
ATOM   1650 C CB   . PRO A 1 117 ? 63.442  124.595 116.747 1.00 115.55 ? 117 PRO A CB   1 
ATOM   1651 C CG   . PRO A 1 117 ? 62.705  123.467 117.407 1.00 115.55 ? 117 PRO A CG   1 
ATOM   1652 C CD   . PRO A 1 117 ? 62.313  122.506 116.303 1.00 115.55 ? 117 PRO A CD   1 
ATOM   1653 H HA   . PRO A 1 117 ? 64.268  124.531 114.841 1.00 115.55 ? 117 PRO A HA   1 
ATOM   1654 H HB2  . PRO A 1 117 ? 64.078  125.000 117.355 1.00 115.55 ? 117 PRO A HB2  1 
ATOM   1655 H HB3  . PRO A 1 117 ? 62.825  125.253 116.391 1.00 115.55 ? 117 PRO A HB3  1 
ATOM   1656 H HG2  . PRO A 1 117 ? 63.285  123.031 118.049 1.00 115.55 ? 117 PRO A HG2  1 
ATOM   1657 H HG3  . PRO A 1 117 ? 61.912  123.814 117.845 1.00 115.55 ? 117 PRO A HG3  1 
ATOM   1658 H HD2  . PRO A 1 117 ? 62.421  121.589 116.604 1.00 115.55 ? 117 PRO A HD2  1 
ATOM   1659 H HD3  . PRO A 1 117 ? 61.405  122.672 116.010 1.00 115.55 ? 117 PRO A HD3  1 
ATOM   1660 N N    . LEU A 1 118 ? 66.590  123.960 115.414 1.00 106.61 ? 118 LEU A N    1 
ATOM   1661 C CA   . LEU A 1 118 ? 67.969  123.535 115.647 1.00 106.61 ? 118 LEU A CA   1 
ATOM   1662 C C    . LEU A 1 118 ? 68.640  124.510 116.611 1.00 106.61 ? 118 LEU A C    1 
ATOM   1663 O O    . LEU A 1 118 ? 68.783  125.698 116.302 1.00 106.61 ? 118 LEU A O    1 
ATOM   1664 C CB   . LEU A 1 118 ? 68.737  123.460 114.329 1.00 106.61 ? 118 LEU A CB   1 
ATOM   1665 C CG   . LEU A 1 118 ? 68.403  122.296 113.393 1.00 106.61 ? 118 LEU A CG   1 
ATOM   1666 C CD1  . LEU A 1 118 ? 66.977  122.390 112.883 1.00 106.61 ? 118 LEU A CD1  1 
ATOM   1667 C CD2  . LEU A 1 118 ? 69.382  122.257 112.234 1.00 106.61 ? 118 LEU A CD2  1 
ATOM   1668 H H    . LEU A 1 118 ? 66.524  124.607 114.853 1.00 106.61 ? 118 LEU A H    1 
ATOM   1669 H HA   . LEU A 1 118 ? 67.975  122.652 116.050 1.00 106.61 ? 118 LEU A HA   1 
ATOM   1670 H HB2  . LEU A 1 118 ? 68.565  124.277 113.834 1.00 106.61 ? 118 LEU A HB2  1 
ATOM   1671 H HB3  . LEU A 1 118 ? 69.681  123.399 114.531 1.00 106.61 ? 118 LEU A HB3  1 
ATOM   1672 H HG   . LEU A 1 118 ? 68.492  121.466 113.885 1.00 106.61 ? 118 LEU A HG   1 
ATOM   1673 H HD11 . LEU A 1 118 ? 66.853  121.748 112.166 1.00 106.61 ? 118 LEU A HD11 1 
ATOM   1674 H HD12 . LEU A 1 118 ? 66.373  122.188 113.613 1.00 106.61 ? 118 LEU A HD12 1 
ATOM   1675 H HD13 . LEU A 1 118 ? 66.814  123.288 112.554 1.00 106.61 ? 118 LEU A HD13 1 
ATOM   1676 H HD21 . LEU A 1 118 ? 69.188  121.481 111.684 1.00 106.61 ? 118 LEU A HD21 1 
ATOM   1677 H HD22 . LEU A 1 118 ? 69.284  123.067 111.710 1.00 106.61 ? 118 LEU A HD22 1 
ATOM   1678 H HD23 . LEU A 1 118 ? 70.284  122.197 112.586 1.00 106.61 ? 118 LEU A HD23 1 
ATOM   1679 N N    . GLY A 1 119 ? 69.049  124.008 117.775 1.00 103.34 ? 119 GLY A N    1 
ATOM   1680 C CA   . GLY A 1 119 ? 69.740  124.808 118.760 1.00 103.34 ? 119 GLY A CA   1 
ATOM   1681 C C    . GLY A 1 119 ? 71.246  124.623 118.710 1.00 103.34 ? 119 GLY A C    1 
ATOM   1682 O O    . GLY A 1 119 ? 71.790  124.005 117.790 1.00 103.34 ? 119 GLY A O    1 
ATOM   1683 H H    . GLY A 1 119 ? 68.930  123.192 118.015 1.00 103.34 ? 119 GLY A H    1 
ATOM   1684 H HA2  . GLY A 1 119 ? 69.542  125.746 118.619 1.00 103.34 ? 119 GLY A HA2  1 
ATOM   1685 H HA3  . GLY A 1 119 ? 69.432  124.560 119.646 1.00 103.34 ? 119 GLY A HA3  1 
ATOM   1686 N N    . PRO A 1 120 ? 71.950  125.173 119.696 1.00 98.34  ? 120 PRO A N    1 
ATOM   1687 C CA   . PRO A 1 120 ? 73.400  124.977 119.775 1.00 98.34  ? 120 PRO A CA   1 
ATOM   1688 C C    . PRO A 1 120 ? 73.759  123.592 120.296 1.00 98.34  ? 120 PRO A C    1 
ATOM   1689 O O    . PRO A 1 120 ? 72.966  122.912 120.948 1.00 98.34  ? 120 PRO A O    1 
ATOM   1690 C CB   . PRO A 1 120 ? 73.846  126.062 120.758 1.00 98.34  ? 120 PRO A CB   1 
ATOM   1691 C CG   . PRO A 1 120 ? 72.670  126.248 121.648 1.00 98.34  ? 120 PRO A CG   1 
ATOM   1692 C CD   . PRO A 1 120 ? 71.451  126.033 120.783 1.00 98.34  ? 120 PRO A CD   1 
ATOM   1693 H HA   . PRO A 1 120 ? 73.817  125.123 118.912 1.00 98.34  ? 120 PRO A HA   1 
ATOM   1694 H HB2  . PRO A 1 120 ? 74.616  125.755 121.264 1.00 98.34  ? 120 PRO A HB2  1 
ATOM   1695 H HB3  . PRO A 1 120 ? 74.050  126.880 120.279 1.00 98.34  ? 120 PRO A HB3  1 
ATOM   1696 H HG2  . PRO A 1 120 ? 72.700  125.594 122.364 1.00 98.34  ? 120 PRO A HG2  1 
ATOM   1697 H HG3  . PRO A 1 120 ? 72.677  127.148 122.009 1.00 98.34  ? 120 PRO A HG3  1 
ATOM   1698 H HD2  . PRO A 1 120 ? 70.758  125.576 121.285 1.00 98.34  ? 120 PRO A HD2  1 
ATOM   1699 H HD3  . PRO A 1 120 ? 71.134  126.878 120.428 1.00 98.34  ? 120 PRO A HD3  1 
ATOM   1700 N N    . CYS A 1 121 ? 74.990  123.188 119.998 1.00 93.06  ? 121 CYS A N    1 
ATOM   1701 C CA   . CYS A 1 121 ? 75.499  121.873 120.390 1.00 93.06  ? 121 CYS A CA   1 
ATOM   1702 C C    . CYS A 1 121 ? 76.331  121.982 121.667 1.00 93.06  ? 121 CYS A C    1 
ATOM   1703 O O    . CYS A 1 121 ? 77.536  121.735 121.687 1.00 93.06  ? 121 CYS A O    1 
ATOM   1704 C CB   . CYS A 1 121 ? 76.308  121.267 119.248 1.00 93.06  ? 121 CYS A CB   1 
ATOM   1705 S SG   . CYS A 1 121 ? 76.790  119.534 119.455 1.00 93.06  ? 121 CYS A SG   1 
ATOM   1706 H H    . CYS A 1 121 ? 75.561  123.664 119.564 1.00 93.06  ? 121 CYS A H    1 
ATOM   1707 H HA   . CYS A 1 121 ? 74.750  121.284 120.571 1.00 93.06  ? 121 CYS A HA   1 
ATOM   1708 H HB2  . CYS A 1 121 ? 75.781  121.326 118.436 1.00 93.06  ? 121 CYS A HB2  1 
ATOM   1709 H HB3  . CYS A 1 121 ? 77.123  121.783 119.142 1.00 93.06  ? 121 CYS A HB3  1 
ATOM   1710 N N    . GLN A 1 122 ? 75.659  122.361 122.749 1.00 94.42  ? 122 GLN A N    1 
ATOM   1711 C CA   . GLN A 1 122 ? 76.303  122.512 124.047 1.00 94.42  ? 122 GLN A CA   1 
ATOM   1712 C C    . GLN A 1 122 ? 76.404  121.146 124.724 1.00 94.42  ? 122 GLN A C    1 
ATOM   1713 O O    . GLN A 1 122 ? 76.229  120.099 124.096 1.00 94.42  ? 122 GLN A O    1 
ATOM   1714 C CB   . GLN A 1 122 ? 75.539  123.521 124.899 1.00 94.42  ? 122 GLN A CB   1 
ATOM   1715 C CG   . GLN A 1 122 ? 74.129  123.087 125.253 1.00 94.42  ? 122 GLN A CG   1 
ATOM   1716 C CD   . GLN A 1 122 ? 73.361  124.159 125.996 1.00 94.42  ? 122 GLN A CD   1 
ATOM   1717 O OE1  . GLN A 1 122 ? 73.452  124.269 127.217 1.00 94.42  ? 122 GLN A OE1  1 
ATOM   1718 N NE2  . GLN A 1 122 ? 72.597  124.956 125.259 1.00 94.42  ? 122 GLN A NE2  1 
ATOM   1719 H H    . GLN A 1 122 ? 74.817  122.536 122.756 1.00 94.42  ? 122 GLN A H    1 
ATOM   1720 H HA   . GLN A 1 122 ? 77.203  122.849 123.917 1.00 94.42  ? 122 GLN A HA   1 
ATOM   1721 H HB2  . GLN A 1 122 ? 76.023  123.664 125.728 1.00 94.42  ? 122 GLN A HB2  1 
ATOM   1722 H HB3  . GLN A 1 122 ? 75.475  124.355 124.409 1.00 94.42  ? 122 GLN A HB3  1 
ATOM   1723 H HG2  . GLN A 1 122 ? 73.644  122.881 124.438 1.00 94.42  ? 122 GLN A HG2  1 
ATOM   1724 H HG3  . GLN A 1 122 ? 74.172  122.303 125.821 1.00 94.42  ? 122 GLN A HG3  1 
ATOM   1725 H HE21 . GLN A 1 122 ? 72.559  124.848 124.407 1.00 94.42  ? 122 GLN A HE21 1 
ATOM   1726 H HE22 . GLN A 1 122 ? 72.140  125.581 125.634 1.00 94.42  ? 122 GLN A HE22 1 
ATOM   1727 N N    . HIS A 1 123 ? 76.695  121.141 126.025 1.00 94.00  ? 123 HIS A N    1 
ATOM   1728 C CA   . HIS A 1 123 ? 76.863  119.903 126.784 1.00 94.00  ? 123 HIS A CA   1 
ATOM   1729 C C    . HIS A 1 123 ? 77.959  119.028 126.186 1.00 94.00  ? 123 HIS A C    1 
ATOM   1730 O O    . HIS A 1 123 ? 77.894  117.799 126.251 1.00 94.00  ? 123 HIS A O    1 
ATOM   1731 C CB   . HIS A 1 123 ? 75.551  119.117 126.873 1.00 94.00  ? 123 HIS A CB   1 
ATOM   1732 C CG   . HIS A 1 123 ? 74.533  119.736 127.779 1.00 94.00  ? 123 HIS A CG   1 
ATOM   1733 N ND1  . HIS A 1 123 ? 73.391  120.348 127.310 1.00 94.00  ? 123 HIS A ND1  1 
ATOM   1734 C CD2  . HIS A 1 123 ? 74.485  119.835 129.129 1.00 94.00  ? 123 HIS A CD2  1 
ATOM   1735 C CE1  . HIS A 1 123 ? 72.684  120.798 128.331 1.00 94.00  ? 123 HIS A CE1  1 
ATOM   1736 N NE2  . HIS A 1 123 ? 73.326  120.500 129.446 1.00 94.00  ? 123 HIS A NE2  1 
ATOM   1737 H H    . HIS A 1 123 ? 76.805  121.851 126.497 1.00 94.00  ? 123 HIS A H    1 
ATOM   1738 H HA   . HIS A 1 123 ? 77.130  120.128 127.689 1.00 94.00  ? 123 HIS A HA   1 
ATOM   1739 H HB2  . HIS A 1 123 ? 75.159  119.053 125.988 1.00 94.00  ? 123 HIS A HB2  1 
ATOM   1740 H HB3  . HIS A 1 123 ? 75.739  118.228 127.212 1.00 94.00  ? 123 HIS A HB3  1 
ATOM   1741 H HD2  . HIS A 1 123 ? 75.119  119.513 129.728 1.00 94.00  ? 123 HIS A HD2  1 
ATOM   1742 H HE1  . HIS A 1 123 ? 71.872  121.249 128.274 1.00 94.00  ? 123 HIS A HE1  1 
ATOM   1743 H HE2  . HIS A 1 123 ? 73.062  120.691 130.242 1.00 94.00  ? 123 HIS A HE2  1 
ATOM   1744 N N    . GLY A 1 124 ? 78.974  119.655 125.599 1.00 85.88  ? 124 GLY A N    1 
ATOM   1745 C CA   . GLY A 1 124 ? 80.059  118.891 125.012 1.00 85.88  ? 124 GLY A CA   1 
ATOM   1746 C C    . GLY A 1 124 ? 79.560  117.953 123.932 1.00 85.88  ? 124 GLY A C    1 
ATOM   1747 O O    . GLY A 1 124 ? 78.749  118.321 123.076 1.00 85.88  ? 124 GLY A O    1 
ATOM   1748 H H    . GLY A 1 124 ? 79.055  120.508 125.530 1.00 85.88  ? 124 GLY A H    1 
ATOM   1749 H HA2  . GLY A 1 124 ? 80.707  119.496 124.619 1.00 85.88  ? 124 GLY A HA2  1 
ATOM   1750 H HA3  . GLY A 1 124 ? 80.499  118.367 125.699 1.00 85.88  ? 124 GLY A HA3  1 
ATOM   1751 N N    . TRP A 1 125 ? 80.052  116.719 123.969 1.00 78.60  ? 125 TRP A N    1 
ATOM   1752 C CA   . TRP A 1 125 ? 79.718  115.730 122.958 1.00 78.60  ? 125 TRP A CA   1 
ATOM   1753 C C    . TRP A 1 125 ? 79.759  114.344 123.584 1.00 78.60  ? 125 TRP A C    1 
ATOM   1754 O O    . TRP A 1 125 ? 80.322  114.145 124.663 1.00 78.60  ? 125 TRP A O    1 
ATOM   1755 C CB   . TRP A 1 125 ? 80.680  115.803 121.768 1.00 78.60  ? 125 TRP A CB   1 
ATOM   1756 C CG   . TRP A 1 125 ? 80.322  116.841 120.753 1.00 78.60  ? 125 TRP A CG   1 
ATOM   1757 C CD1  . TRP A 1 125 ? 79.546  116.665 119.647 1.00 78.60  ? 125 TRP A CD1  1 
ATOM   1758 C CD2  . TRP A 1 125 ? 80.733  118.213 120.741 1.00 78.60  ? 125 TRP A CD2  1 
ATOM   1759 N NE1  . TRP A 1 125 ? 79.445  117.841 118.948 1.00 78.60  ? 125 TRP A NE1  1 
ATOM   1760 C CE2  . TRP A 1 125 ? 80.164  118.807 119.598 1.00 78.60  ? 125 TRP A CE2  1 
ATOM   1761 C CE3  . TRP A 1 125 ? 81.523  118.996 121.584 1.00 78.60  ? 125 TRP A CE3  1 
ATOM   1762 C CZ2  . TRP A 1 125 ? 80.360  120.147 119.279 1.00 78.60  ? 125 TRP A CZ2  1 
ATOM   1763 C CZ3  . TRP A 1 125 ? 81.715  120.328 121.265 1.00 78.60  ? 125 TRP A CZ3  1 
ATOM   1764 C CH2  . TRP A 1 125 ? 81.137  120.889 120.122 1.00 78.60  ? 125 TRP A CH2  1 
ATOM   1765 H H    . TRP A 1 125 ? 80.588  116.430 124.577 1.00 78.60  ? 125 TRP A H    1 
ATOM   1766 H HA   . TRP A 1 125 ? 78.818  115.891 122.634 1.00 78.60  ? 125 TRP A HA   1 
ATOM   1767 H HB2  . TRP A 1 125 ? 81.569  116.007 122.098 1.00 78.60  ? 125 TRP A HB2  1 
ATOM   1768 H HB3  . TRP A 1 125 ? 80.686  114.943 121.320 1.00 78.60  ? 125 TRP A HB3  1 
ATOM   1769 H HD1  . TRP A 1 125 ? 79.143  115.864 119.401 1.00 78.60  ? 125 TRP A HD1  1 
ATOM   1770 H HE1  . TRP A 1 125 ? 79.001  117.953 118.220 1.00 78.60  ? 125 TRP A HE1  1 
ATOM   1771 H HE3  . TRP A 1 125 ? 81.911  118.630 122.346 1.00 78.60  ? 125 TRP A HE3  1 
ATOM   1772 H HZ2  . TRP A 1 125 ? 79.975  120.523 118.520 1.00 78.60  ? 125 TRP A HZ2  1 
ATOM   1773 H HZ3  . TRP A 1 125 ? 82.240  120.859 121.818 1.00 78.60  ? 125 TRP A HZ3  1 
ATOM   1774 H HH2  . TRP A 1 125 ? 81.284  121.787 119.932 1.00 78.60  ? 125 TRP A HH2  1 
ATOM   1775 N N    . VAL A 1 126 ? 79.140  113.388 122.896 1.00 78.70  ? 126 VAL A N    1 
ATOM   1776 C CA   . VAL A 1 126 ? 79.205  111.975 123.252 1.00 78.70  ? 126 VAL A CA   1 
ATOM   1777 C C    . VAL A 1 126 ? 79.882  111.240 122.105 1.00 78.70  ? 126 VAL A C    1 
ATOM   1778 O O    . VAL A 1 126 ? 79.488  111.395 120.943 1.00 78.70  ? 126 VAL A O    1 
ATOM   1779 C CB   . VAL A 1 126 ? 77.808  111.397 123.536 1.00 78.70  ? 126 VAL A CB   1 
ATOM   1780 C CG1  . VAL A 1 126 ? 76.995  111.299 122.254 1.00 78.70  ? 126 VAL A CG1  1 
ATOM   1781 C CG2  . VAL A 1 126 ? 77.923  110.039 124.208 1.00 78.70  ? 126 VAL A CG2  1 
ATOM   1782 H H    . VAL A 1 126 ? 78.662  113.540 122.197 1.00 78.70  ? 126 VAL A H    1 
ATOM   1783 H HA   . VAL A 1 126 ? 79.748  111.865 124.048 1.00 78.70  ? 126 VAL A HA   1 
ATOM   1784 H HB   . VAL A 1 126 ? 77.338  111.991 124.141 1.00 78.70  ? 126 VAL A HB   1 
ATOM   1785 H HG11 . VAL A 1 126 ? 76.056  111.213 122.482 1.00 78.70  ? 126 VAL A HG11 1 
ATOM   1786 H HG12 . VAL A 1 126 ? 77.135  112.102 121.728 1.00 78.70  ? 126 VAL A HG12 1 
ATOM   1787 H HG13 . VAL A 1 126 ? 77.285  110.521 121.752 1.00 78.70  ? 126 VAL A HG13 1 
ATOM   1788 H HG21 . VAL A 1 126 ? 77.032  109.683 124.352 1.00 78.70  ? 126 VAL A HG21 1 
ATOM   1789 H HG22 . VAL A 1 126 ? 78.429  109.443 123.635 1.00 78.70  ? 126 VAL A HG22 1 
ATOM   1790 H HG23 . VAL A 1 126 ? 78.378  110.147 125.058 1.00 78.70  ? 126 VAL A HG23 1 
ATOM   1791 N N    . TYR A 1 127 ? 80.899  110.449 122.426 1.00 63.48  ? 127 TYR A N    1 
ATOM   1792 C CA   . TYR A 1 127 ? 81.726  109.795 121.426 1.00 63.48  ? 127 TYR A CA   1 
ATOM   1793 C C    . TYR A 1 127 ? 81.459  108.296 121.405 1.00 63.48  ? 127 TYR A C    1 
ATOM   1794 O O    . TYR A 1 127 ? 81.025  107.709 122.400 1.00 63.48  ? 127 TYR A O    1 
ATOM   1795 C CB   . TYR A 1 127 ? 83.206  110.057 121.696 1.00 63.48  ? 127 TYR A CB   1 
ATOM   1796 C CG   . TYR A 1 127 ? 83.550  111.523 121.720 1.00 63.48  ? 127 TYR A CG   1 
ATOM   1797 C CD1  . TYR A 1 127 ? 83.483  112.248 122.895 1.00 63.48  ? 127 TYR A CD1  1 
ATOM   1798 C CD2  . TYR A 1 127 ? 83.933  112.185 120.566 1.00 63.48  ? 127 TYR A CD2  1 
ATOM   1799 C CE1  . TYR A 1 127 ? 83.793  113.586 122.923 1.00 63.48  ? 127 TYR A CE1  1 
ATOM   1800 C CE2  . TYR A 1 127 ? 84.247  113.523 120.585 1.00 63.48  ? 127 TYR A CE2  1 
ATOM   1801 C CZ   . TYR A 1 127 ? 84.172  114.220 121.766 1.00 63.48  ? 127 TYR A CZ   1 
ATOM   1802 O OH   . TYR A 1 127 ? 84.481  115.557 121.796 1.00 63.48  ? 127 TYR A OH   1 
ATOM   1803 H H    . TYR A 1 127 ? 81.131  110.271 123.235 1.00 63.48  ? 127 TYR A H    1 
ATOM   1804 H HA   . TYR A 1 127 ? 81.513  110.151 120.550 1.00 63.48  ? 127 TYR A HA   1 
ATOM   1805 H HB2  . TYR A 1 127 ? 83.441  109.681 122.558 1.00 63.48  ? 127 TYR A HB2  1 
ATOM   1806 H HB3  . TYR A 1 127 ? 83.733  109.638 120.998 1.00 63.48  ? 127 TYR A HB3  1 
ATOM   1807 H HD1  . TYR A 1 127 ? 83.226  111.822 123.681 1.00 63.48  ? 127 TYR A HD1  1 
ATOM   1808 H HD2  . TYR A 1 127 ? 83.983  111.715 119.765 1.00 63.48  ? 127 TYR A HD2  1 
ATOM   1809 H HE1  . TYR A 1 127 ? 83.745  114.061 123.722 1.00 63.48  ? 127 TYR A HE1  1 
ATOM   1810 H HE2  . TYR A 1 127 ? 84.503  113.955 119.803 1.00 63.48  ? 127 TYR A HE2  1 
ATOM   1811 H HH   . TYR A 1 127 ? 84.935  115.763 121.120 1.00 63.48  ? 127 TYR A HH   1 
ATOM   1812 N N    . ASP A 1 128 ? 81.731  107.682 120.253 1.00 68.55  ? 128 ASP A N    1 
ATOM   1813 C CA   . ASP A 1 128 ? 81.410  106.273 120.052 1.00 68.55  ? 128 ASP A CA   1 
ATOM   1814 C C    . ASP A 1 128 ? 82.443  105.365 120.709 1.00 68.55  ? 128 ASP A C    1 
ATOM   1815 O O    . ASP A 1 128 ? 82.104  104.527 121.552 1.00 68.55  ? 128 ASP A O    1 
ATOM   1816 C CB   . ASP A 1 128 ? 81.312  105.976 118.553 1.00 68.55  ? 128 ASP A CB   1 
ATOM   1817 C CG   . ASP A 1 128 ? 80.916  104.543 118.267 1.00 68.55  ? 128 ASP A CG   1 
ATOM   1818 O OD1  . ASP A 1 128 ? 80.549  103.822 119.218 1.00 68.55  ? 128 ASP A OD1  1 
ATOM   1819 O OD2  . ASP A 1 128 ? 80.973  104.135 117.089 1.00 68.55  ? 128 ASP A OD2  1 
ATOM   1820 H H    . ASP A 1 128 ? 82.100  108.059 119.575 1.00 68.55  ? 128 ASP A H    1 
ATOM   1821 H HA   . ASP A 1 128 ? 80.546  106.085 120.452 1.00 68.55  ? 128 ASP A HA   1 
ATOM   1822 H HB2  . ASP A 1 128 ? 80.643  106.557 118.159 1.00 68.55  ? 128 ASP A HB2  1 
ATOM   1823 H HB3  . ASP A 1 128 ? 82.176  106.136 118.142 1.00 68.55  ? 128 ASP A HB3  1 
ATOM   1824 N N    . THR A 1 129 ? 83.707  105.518 120.335 1.00 62.58  ? 129 THR A N    1 
ATOM   1825 C CA   . THR A 1 129 ? 84.733  104.598 120.802 1.00 62.58  ? 129 THR A CA   1 
ATOM   1826 C C    . THR A 1 129 ? 84.882  104.690 122.319 1.00 62.58  ? 129 THR A C    1 
ATOM   1827 O O    . THR A 1 129 ? 84.805  105.786 122.885 1.00 62.58  ? 129 THR A O    1 
ATOM   1828 C CB   . THR A 1 129 ? 86.074  104.905 120.138 1.00 62.58  ? 129 THR A CB   1 
ATOM   1829 O OG1  . THR A 1 129 ? 87.078  104.028 120.664 1.00 62.58  ? 129 THR A OG1  1 
ATOM   1830 C CG2  . THR A 1 129 ? 86.485  106.352 120.392 1.00 62.58  ? 129 THR A CG2  1 
ATOM   1831 H H    . THR A 1 129 ? 83.989  106.138 119.812 1.00 62.58  ? 129 THR A H    1 
ATOM   1832 H HA   . THR A 1 129 ? 84.473  103.695 120.562 1.00 62.58  ? 129 THR A HA   1 
ATOM   1833 H HB   . THR A 1 129 ? 85.998  104.771 119.180 1.00 62.58  ? 129 THR A HB   1 
ATOM   1834 H HG1  . THR A 1 129 ? 87.822  104.197 120.311 1.00 62.58  ? 129 THR A HG1  1 
ATOM   1835 H HG21 . THR A 1 129 ? 87.330  106.537 119.956 1.00 62.58  ? 129 THR A HG21 1 
ATOM   1836 H HG22 . THR A 1 129 ? 85.814  106.957 120.041 1.00 62.58  ? 129 THR A HG22 1 
ATOM   1837 H HG23 . THR A 1 129 ? 86.585  106.511 121.344 1.00 62.58  ? 129 THR A HG23 1 
ATOM   1838 N N    . PRO A 1 130 ? 85.094  103.566 123.010 1.00 63.30  ? 130 PRO A N    1 
ATOM   1839 C CA   . PRO A 1 130 ? 85.343  103.646 124.457 1.00 63.30  ? 130 PRO A CA   1 
ATOM   1840 C C    . PRO A 1 130 ? 86.611  104.400 124.805 1.00 63.30  ? 130 PRO A C    1 
ATOM   1841 O O    . PRO A 1 130 ? 86.665  105.056 125.853 1.00 63.30  ? 130 PRO A O    1 
ATOM   1842 C CB   . PRO A 1 130 ? 85.425  102.172 124.878 1.00 63.30  ? 130 PRO A CB   1 
ATOM   1843 C CG   . PRO A 1 130 ? 85.868  101.462 123.653 1.00 63.30  ? 130 PRO A CG   1 
ATOM   1844 C CD   . PRO A 1 130 ? 85.225  102.188 122.507 1.00 63.30  ? 130 PRO A CD   1 
ATOM   1845 H HA   . PRO A 1 130 ? 84.590  104.064 124.904 1.00 63.30  ? 130 PRO A HA   1 
ATOM   1846 H HB2  . PRO A 1 130 ? 86.073  102.069 125.592 1.00 63.30  ? 130 PRO A HB2  1 
ATOM   1847 H HB3  . PRO A 1 130 ? 84.549  101.863 125.158 1.00 63.30  ? 130 PRO A HB3  1 
ATOM   1848 H HG2  . PRO A 1 130 ? 86.835  101.504 123.586 1.00 63.30  ? 130 PRO A HG2  1 
ATOM   1849 H HG3  . PRO A 1 130 ? 85.568  100.540 123.686 1.00 63.30  ? 130 PRO A HG3  1 
ATOM   1850 H HD2  . PRO A 1 130 ? 85.800  102.164 121.726 1.00 63.30  ? 130 PRO A HD2  1 
ATOM   1851 H HD3  . PRO A 1 130 ? 84.351  101.813 122.318 1.00 63.30  ? 130 PRO A HD3  1 
ATOM   1852 N N    . GLY A 1 131 ? 87.632  104.328 123.959 1.00 56.62  ? 131 GLY A N    1 
ATOM   1853 C CA   . GLY A 1 131 ? 88.877  105.010 124.235 1.00 56.62  ? 131 GLY A CA   1 
ATOM   1854 C C    . GLY A 1 131 ? 88.764  106.507 124.032 1.00 56.62  ? 131 GLY A C    1 
ATOM   1855 O O    . GLY A 1 131 ? 87.782  107.029 123.503 1.00 56.62  ? 131 GLY A O    1 
ATOM   1856 H H    . GLY A 1 131 ? 87.624  103.891 123.219 1.00 56.62  ? 131 GLY A H    1 
ATOM   1857 H HA2  . GLY A 1 131 ? 89.141  104.843 125.153 1.00 56.62  ? 131 GLY A HA2  1 
ATOM   1858 H HA3  . GLY A 1 131 ? 89.570  104.670 123.648 1.00 56.62  ? 131 GLY A HA3  1 
ATOM   1859 N N    . SER A 1 132 ? 89.803  107.212 124.469 1.00 53.56  ? 132 SER A N    1 
ATOM   1860 C CA   . SER A 1 132 ? 89.861  108.665 124.391 1.00 53.56  ? 132 SER A CA   1 
ATOM   1861 C C    . SER A 1 132 ? 91.073  109.079 123.575 1.00 53.56  ? 132 SER A C    1 
ATOM   1862 O O    . SER A 1 132 ? 92.156  108.506 123.728 1.00 53.56  ? 132 SER A O    1 
ATOM   1863 C CB   . SER A 1 132 ? 89.927  109.289 125.786 1.00 53.56  ? 132 SER A CB   1 
ATOM   1864 O OG   . SER A 1 132 ? 91.083  108.859 126.480 1.00 53.56  ? 132 SER A OG   1 
ATOM   1865 H H    . SER A 1 132 ? 90.503  106.860 124.823 1.00 53.56  ? 132 SER A H    1 
ATOM   1866 H HA   . SER A 1 132 ? 89.066  108.998 123.946 1.00 53.56  ? 132 SER A HA   1 
ATOM   1867 H HB2  . SER A 1 132 ? 89.952  110.255 125.697 1.00 53.56  ? 132 SER A HB2  1 
ATOM   1868 H HB3  . SER A 1 132 ? 89.140  109.024 126.287 1.00 53.56  ? 132 SER A HB3  1 
ATOM   1869 H HG   . SER A 1 132 ? 91.039  108.034 126.627 1.00 53.56  ? 132 SER A HG   1 
ATOM   1870 N N    . SER A 1 133 ? 90.887  110.066 122.708 1.00 52.36  ? 133 SER A N    1 
ATOM   1871 C CA   . SER A 1 133 ? 91.949  110.612 121.880 1.00 52.36  ? 133 SER A CA   1 
ATOM   1872 C C    . SER A 1 133 ? 92.079  112.107 122.130 1.00 52.36  ? 133 SER A C    1 
ATOM   1873 O O    . SER A 1 133 ? 91.307  112.705 122.882 1.00 52.36  ? 133 SER A O    1 
ATOM   1874 C CB   . SER A 1 133 ? 91.680  110.353 120.397 1.00 52.36  ? 133 SER A CB   1 
ATOM   1875 O OG   . SER A 1 133 ? 92.567  111.106 119.591 1.00 52.36  ? 133 SER A OG   1 
ATOM   1876 H H    . SER A 1 133 ? 90.126  110.446 122.577 1.00 52.36  ? 133 SER A H    1 
ATOM   1877 H HA   . SER A 1 133 ? 92.790  110.190 122.114 1.00 52.36  ? 133 SER A HA   1 
ATOM   1878 H HB2  . SER A 1 133 ? 91.812  109.412 120.215 1.00 52.36  ? 133 SER A HB2  1 
ATOM   1879 H HB3  . SER A 1 133 ? 90.768  110.608 120.189 1.00 52.36  ? 133 SER A HB3  1 
ATOM   1880 H HG   . SER A 1 133 ? 93.356  110.860 119.734 1.00 52.36  ? 133 SER A HG   1 
ATOM   1881 N N    . ILE A 1 134 ? 93.070  112.717 121.475 1.00 50.26  ? 134 ILE A N    1 
ATOM   1882 C CA   . ILE A 1 134 ? 93.277  114.151 121.638 1.00 50.26  ? 134 ILE A CA   1 
ATOM   1883 C C    . ILE A 1 134 ? 92.037  114.916 121.206 1.00 50.26  ? 134 ILE A C    1 
ATOM   1884 O O    . ILE A 1 134 ? 91.708  115.958 121.786 1.00 50.26  ? 134 ILE A O    1 
ATOM   1885 C CB   . ILE A 1 134 ? 94.522  114.610 120.855 1.00 50.26  ? 134 ILE A CB   1 
ATOM   1886 C CG1  . ILE A 1 134 ? 94.918  116.033 121.251 1.00 50.26  ? 134 ILE A CG1  1 
ATOM   1887 C CG2  . ILE A 1 134 ? 94.253  114.571 119.373 1.00 50.26  ? 134 ILE A CG2  1 
ATOM   1888 C CD1  . ILE A 1 134 ? 95.469  116.149 122.652 1.00 50.26  ? 134 ILE A CD1  1 
ATOM   1889 H H    . ILE A 1 134 ? 93.624  112.330 120.944 1.00 50.26  ? 134 ILE A H    1 
ATOM   1890 H HA   . ILE A 1 134 ? 93.427  114.337 122.578 1.00 50.26  ? 134 ILE A HA   1 
ATOM   1891 H HB   . ILE A 1 134 ? 95.257  114.010 121.056 1.00 50.26  ? 134 ILE A HB   1 
ATOM   1892 H HG12 . ILE A 1 134 ? 95.603  116.346 120.639 1.00 50.26  ? 134 ILE A HG12 1 
ATOM   1893 H HG13 . ILE A 1 134 ? 94.139  116.607 121.191 1.00 50.26  ? 134 ILE A HG13 1 
ATOM   1894 H HG21 . ILE A 1 134 ? 95.089  114.431 118.901 1.00 50.26  ? 134 ILE A HG21 1 
ATOM   1895 H HG22 . ILE A 1 134 ? 93.640  113.845 119.192 1.00 50.26  ? 134 ILE A HG22 1 
ATOM   1896 H HG23 . ILE A 1 134 ? 93.854  115.413 119.104 1.00 50.26  ? 134 ILE A HG23 1 
ATOM   1897 H HD11 . ILE A 1 134 ? 95.818  117.045 122.780 1.00 50.26  ? 134 ILE A HD11 1 
ATOM   1898 H HD12 . ILE A 1 134 ? 94.759  115.978 123.289 1.00 50.26  ? 134 ILE A HD12 1 
ATOM   1899 H HD13 . ILE A 1 134 ? 96.181  115.499 122.765 1.00 50.26  ? 134 ILE A HD13 1 
ATOM   1900 N N    . VAL A 1 135 ? 91.330  114.423 120.188 1.00 53.34  ? 135 VAL A N    1 
ATOM   1901 C CA   . VAL A 1 135 ? 90.094  115.076 119.771 1.00 53.34  ? 135 VAL A CA   1 
ATOM   1902 C C    . VAL A 1 135 ? 89.059  115.004 120.884 1.00 53.34  ? 135 VAL A C    1 
ATOM   1903 O O    . VAL A 1 135 ? 88.403  116.001 121.208 1.00 53.34  ? 135 VAL A O    1 
ATOM   1904 C CB   . VAL A 1 135 ? 89.569  114.445 118.468 1.00 53.34  ? 135 VAL A CB   1 
ATOM   1905 C CG1  . VAL A 1 135 ? 88.345  115.192 117.968 1.00 53.34  ? 135 VAL A CG1  1 
ATOM   1906 C CG2  . VAL A 1 135 ? 90.655  114.435 117.407 1.00 53.34  ? 135 VAL A CG2  1 
ATOM   1907 H H    . VAL A 1 135 ? 91.541  113.724 119.734 1.00 53.34  ? 135 VAL A H    1 
ATOM   1908 H HA   . VAL A 1 135 ? 90.278  116.012 119.594 1.00 53.34  ? 135 VAL A HA   1 
ATOM   1909 H HB   . VAL A 1 135 ? 89.310  113.526 118.642 1.00 53.34  ? 135 VAL A HB   1 
ATOM   1910 H HG11 . VAL A 1 135 ? 88.060  114.801 117.127 1.00 53.34  ? 135 VAL A HG11 1 
ATOM   1911 H HG12 . VAL A 1 135 ? 87.633  115.118 118.623 1.00 53.34  ? 135 VAL A HG12 1 
ATOM   1912 H HG13 . VAL A 1 135 ? 88.578  116.124 117.835 1.00 53.34  ? 135 VAL A HG13 1 
ATOM   1913 H HG21 . VAL A 1 135 ? 90.250  114.261 116.543 1.00 53.34  ? 135 VAL A HG21 1 
ATOM   1914 H HG22 . VAL A 1 135 ? 91.095  115.300 117.398 1.00 53.34  ? 135 VAL A HG22 1 
ATOM   1915 H HG23 . VAL A 1 135 ? 91.297  113.740 117.619 1.00 53.34  ? 135 VAL A HG23 1 
ATOM   1916 N N    . THR A 1 136 ? 88.907  113.831 121.499 1.00 55.49  ? 136 THR A N    1 
ATOM   1917 C CA   . THR A 1 136 ? 87.938  113.692 122.580 1.00 55.49  ? 136 THR A CA   1 
ATOM   1918 C C    . THR A 1 136 ? 88.330  114.522 123.794 1.00 55.49  ? 136 THR A C    1 
ATOM   1919 O O    . THR A 1 136 ? 87.457  114.971 124.544 1.00 55.49  ? 136 THR A O    1 
ATOM   1920 C CB   . THR A 1 136 ? 87.798  112.223 122.979 1.00 55.49  ? 136 THR A CB   1 
ATOM   1921 O OG1  . THR A 1 136 ? 89.076  111.700 123.358 1.00 55.49  ? 136 THR A OG1  1 
ATOM   1922 C CG2  . THR A 1 136 ? 87.246  111.408 121.827 1.00 55.49  ? 136 THR A CG2  1 
ATOM   1923 H H    . THR A 1 136 ? 89.343  113.114 121.312 1.00 55.49  ? 136 THR A H    1 
ATOM   1924 H HA   . THR A 1 136 ? 87.073  114.002 122.271 1.00 55.49  ? 136 THR A HA   1 
ATOM   1925 H HB   . THR A 1 136 ? 87.185  112.149 123.727 1.00 55.49  ? 136 THR A HB   1 
ATOM   1926 H HG1  . THR A 1 136 ? 89.337  112.065 124.068 1.00 55.49  ? 136 THR A HG1  1 
ATOM   1927 H HG21 . THR A 1 136 ? 87.079  110.497 122.115 1.00 55.49  ? 136 THR A HG21 1 
ATOM   1928 H HG22 . THR A 1 136 ? 86.416  111.798 121.518 1.00 55.49  ? 136 THR A HG22 1 
ATOM   1929 H HG23 . THR A 1 136 ? 87.881  111.397 121.093 1.00 55.49  ? 136 THR A HG23 1 
ATOM   1930 N N    . GLU A 1 137 ? 89.627  114.736 124.004 1.00 52.53  ? 137 GLU A N    1 
ATOM   1931 C CA   . GLU A 1 137 ? 90.080  115.452 125.191 1.00 52.53  ? 137 GLU A CA   1 
ATOM   1932 C C    . GLU A 1 137 ? 89.544  116.878 125.209 1.00 52.53  ? 137 GLU A C    1 
ATOM   1933 O O    . GLU A 1 137 ? 88.781  117.260 126.102 1.00 52.53  ? 137 GLU A O    1 
ATOM   1934 C CB   . GLU A 1 137 ? 91.608  115.452 125.244 1.00 52.53  ? 137 GLU A CB   1 
ATOM   1935 C CG   . GLU A 1 137 ? 92.182  116.049 126.513 1.00 52.53  ? 137 GLU A CG   1 
ATOM   1936 C CD   . GLU A 1 137 ? 91.855  115.222 127.737 1.00 52.53  ? 137 GLU A CD   1 
ATOM   1937 O OE1  . GLU A 1 137 ? 91.500  114.036 127.574 1.00 52.53  ? 137 GLU A OE1  1 
ATOM   1938 O OE2  . GLU A 1 137 ? 91.954  115.757 128.860 1.00 52.53  ? 137 GLU A OE2  1 
ATOM   1939 H H    . GLU A 1 137 ? 90.259  114.479 123.481 1.00 52.53  ? 137 GLU A H    1 
ATOM   1940 H HA   . GLU A 1 137 ? 89.749  114.996 125.981 1.00 52.53  ? 137 GLU A HA   1 
ATOM   1941 H HB2  . GLU A 1 137 ? 91.922  114.537 125.178 1.00 52.53  ? 137 GLU A HB2  1 
ATOM   1942 H HB3  . GLU A 1 137 ? 91.945  115.968 124.496 1.00 52.53  ? 137 GLU A HB3  1 
ATOM   1943 H HG2  . GLU A 1 137 ? 93.147  116.094 126.431 1.00 52.53  ? 137 GLU A HG2  1 
ATOM   1944 H HG3  . GLU A 1 137 ? 91.819  116.939 126.644 1.00 52.53  ? 137 GLU A HG3  1 
ATOM   1945 N N    . PHE A 1 138 ? 89.931  117.680 124.220 1.00 52.77  ? 138 PHE A N    1 
ATOM   1946 C CA   . PHE A 1 138 ? 89.622  119.102 124.198 1.00 52.77  ? 138 PHE A CA   1 
ATOM   1947 C C    . PHE A 1 138 ? 88.390  119.432 123.363 1.00 52.77  ? 138 PHE A C    1 
ATOM   1948 O O    . PHE A 1 138 ? 88.106  120.613 123.141 1.00 52.77  ? 138 PHE A O    1 
ATOM   1949 C CB   . PHE A 1 138 ? 90.824  119.888 123.674 1.00 52.77  ? 138 PHE A CB   1 
ATOM   1950 C CG   . PHE A 1 138 ? 92.086  119.670 124.462 1.00 52.77  ? 138 PHE A CG   1 
ATOM   1951 C CD1  . PHE A 1 138 ? 92.378  120.458 125.561 1.00 52.77  ? 138 PHE A CD1  1 
ATOM   1952 C CD2  . PHE A 1 138 ? 92.984  118.683 124.097 1.00 52.77  ? 138 PHE A CD2  1 
ATOM   1953 C CE1  . PHE A 1 138 ? 93.539  120.263 126.282 1.00 52.77  ? 138 PHE A CE1  1 
ATOM   1954 C CE2  . PHE A 1 138 ? 94.145  118.485 124.815 1.00 52.77  ? 138 PHE A CE2  1 
ATOM   1955 C CZ   . PHE A 1 138 ? 94.422  119.275 125.907 1.00 52.77  ? 138 PHE A CZ   1 
ATOM   1956 H H    . PHE A 1 138 ? 90.384  117.416 123.538 1.00 52.77  ? 138 PHE A H    1 
ATOM   1957 H HA   . PHE A 1 138 ? 89.450  119.398 125.106 1.00 52.77  ? 138 PHE A HA   1 
ATOM   1958 H HB2  . PHE A 1 138 ? 90.998  119.620 122.759 1.00 52.77  ? 138 PHE A HB2  1 
ATOM   1959 H HB3  . PHE A 1 138 ? 90.616  120.835 123.705 1.00 52.77  ? 138 PHE A HB3  1 
ATOM   1960 H HD1  . PHE A 1 138 ? 91.785  121.127 125.818 1.00 52.77  ? 138 PHE A HD1  1 
ATOM   1961 H HD2  . PHE A 1 138 ? 92.802  118.147 123.359 1.00 52.77  ? 138 PHE A HD2  1 
ATOM   1962 H HE1  . PHE A 1 138 ? 93.724  120.797 127.020 1.00 52.77  ? 138 PHE A HE1  1 
ATOM   1963 H HE2  . PHE A 1 138 ? 94.740  117.817 124.561 1.00 52.77  ? 138 PHE A HE2  1 
ATOM   1964 H HZ   . PHE A 1 138 ? 95.204  119.141 126.393 1.00 52.77  ? 138 PHE A HZ   1 
ATOM   1965 N N    . ASN A 1 139 ? 87.653  118.425 122.897 1.00 55.72  ? 139 ASN A N    1 
ATOM   1966 C CA   . ASN A 1 139 ? 86.431  118.652 122.127 1.00 55.72  ? 139 ASN A CA   1 
ATOM   1967 C C    . ASN A 1 139 ? 86.712  119.466 120.865 1.00 55.72  ? 139 ASN A C    1 
ATOM   1968 O O    . ASN A 1 139 ? 86.010  120.430 120.558 1.00 55.72  ? 139 ASN A O    1 
ATOM   1969 C CB   . ASN A 1 139 ? 85.372  119.347 122.985 1.00 30.00  ? 139 ASN A CB   1 
ATOM   1970 C CG   . ASN A 1 139 ? 84.789  118.434 124.045 1.00 30.00  ? 139 ASN A CG   1 
ATOM   1971 O OD1  . ASN A 1 139 ? 84.825  117.211 123.915 1.00 30.00  ? 139 ASN A OD1  1 
ATOM   1972 N ND2  . ASN A 1 139 ? 84.245  119.026 125.102 1.00 30.00  ? 139 ASN A ND2  1 
ATOM   1973 H H    . ASN A 1 139 ? 87.839  117.594 123.016 1.00 55.72  ? 139 ASN A H    1 
ATOM   1974 H HA   . ASN A 1 139 ? 86.076  117.793 121.849 1.00 55.72  ? 139 ASN A HA   1 
ATOM   1975 N N    . LEU A 1 140 ? 87.753  119.078 120.131 1.00 53.86  ? 140 LEU A N    1 
ATOM   1976 C CA   . LEU A 1 140 ? 88.116  119.739 118.876 1.00 53.86  ? 140 LEU A CA   1 
ATOM   1977 C C    . LEU A 1 140 ? 87.398  119.075 117.701 1.00 53.86  ? 140 LEU A C    1 
ATOM   1978 O O    . LEU A 1 140 ? 88.013  118.586 116.756 1.00 53.86  ? 140 LEU A O    1 
ATOM   1979 C CB   . LEU A 1 140 ? 89.626  119.696 118.679 1.00 53.86  ? 140 LEU A CB   1 
ATOM   1980 C CG   . LEU A 1 140 ? 90.483  119.958 119.913 1.00 53.86  ? 140 LEU A CG   1 
ATOM   1981 C CD1  . LEU A 1 140 ? 91.932  119.638 119.610 1.00 53.86  ? 140 LEU A CD1  1 
ATOM   1982 C CD2  . LEU A 1 140 ? 90.334  121.394 120.370 1.00 53.86  ? 140 LEU A CD2  1 
ATOM   1983 H H    . LEU A 1 140 ? 88.270  118.423 120.339 1.00 53.86  ? 140 LEU A H    1 
ATOM   1984 H HA   . LEU A 1 140 ? 87.841  120.669 118.913 1.00 53.86  ? 140 LEU A HA   1 
ATOM   1985 H HB2  . LEU A 1 140 ? 89.863  118.815 118.350 1.00 53.86  ? 140 LEU A HB2  1 
ATOM   1986 H HB3  . LEU A 1 140 ? 89.865  120.362 118.015 1.00 53.86  ? 140 LEU A HB3  1 
ATOM   1987 H HG   . LEU A 1 140 ? 90.194  119.379 120.635 1.00 53.86  ? 140 LEU A HG   1 
ATOM   1988 H HD11 . LEU A 1 140 ? 92.475  119.879 120.377 1.00 53.86  ? 140 LEU A HD11 1 
ATOM   1989 H HD12 . LEU A 1 140 ? 92.012  118.687 119.434 1.00 53.86  ? 140 LEU A HD12 1 
ATOM   1990 H HD13 . LEU A 1 140 ? 92.212  120.144 118.832 1.00 53.86  ? 140 LEU A HD13 1 
ATOM   1991 H HD21 . LEU A 1 140 ? 90.837  121.518 121.190 1.00 53.86  ? 140 LEU A HD21 1 
ATOM   1992 H HD22 . LEU A 1 140 ? 90.679  121.980 119.679 1.00 53.86  ? 140 LEU A HD22 1 
ATOM   1993 H HD23 . LEU A 1 140 ? 89.395  121.581 120.526 1.00 53.86  ? 140 LEU A HD23 1 
ATOM   1994 N N    . VAL A 1 141 ? 86.068  119.077 117.761 1.00 64.58  ? 141 VAL A N    1 
ATOM   1995 C CA   . VAL A 1 141 ? 85.241  118.259 116.877 1.00 64.58  ? 141 VAL A CA   1 
ATOM   1996 C C    . VAL A 1 141 ? 84.619  119.091 115.757 1.00 64.58  ? 141 VAL A C    1 
ATOM   1997 O O    . VAL A 1 141 ? 84.881  118.850 114.577 1.00 64.58  ? 141 VAL A O    1 
ATOM   1998 C CB   . VAL A 1 141 ? 84.159  117.501 117.676 1.00 64.58  ? 141 VAL A CB   1 
ATOM   1999 C CG1  . VAL A 1 141 ? 83.311  116.652 116.748 1.00 64.58  ? 141 VAL A CG1  1 
ATOM   2000 C CG2  . VAL A 1 141 ? 84.801  116.632 118.741 1.00 64.58  ? 141 VAL A CG2  1 
ATOM   2001 H H    . VAL A 1 141 ? 85.614  119.548 118.320 1.00 64.58  ? 141 VAL A H    1 
ATOM   2002 H HA   . VAL A 1 141 ? 85.807  117.592 116.458 1.00 64.58  ? 141 VAL A HA   1 
ATOM   2003 H HB   . VAL A 1 141 ? 83.578  118.141 118.118 1.00 64.58  ? 141 VAL A HB   1 
ATOM   2004 H HG11 . VAL A 1 141 ? 82.762  116.060 117.284 1.00 64.58  ? 141 VAL A HG11 1 
ATOM   2005 H HG12 . VAL A 1 141 ? 82.746  117.229 116.211 1.00 64.58  ? 141 VAL A HG12 1 
ATOM   2006 H HG13 . VAL A 1 141 ? 83.897  116.132 116.176 1.00 64.58  ? 141 VAL A HG13 1 
ATOM   2007 H HG21 . VAL A 1 141 ? 84.109  116.125 119.194 1.00 64.58  ? 141 VAL A HG21 1 
ATOM   2008 H HG22 . VAL A 1 141 ? 85.430  116.026 118.316 1.00 64.58  ? 141 VAL A HG22 1 
ATOM   2009 H HG23 . VAL A 1 141 ? 85.266  117.198 119.376 1.00 64.58  ? 141 VAL A HG23 1 
ATOM   2010 N N    . CYS A 1 142 ? 83.787  120.073 116.105 1.00 67.56  ? 142 CYS A N    1 
ATOM   2011 C CA   . CYS A 1 142 ? 82.933  120.746 115.132 1.00 67.56  ? 142 CYS A CA   1 
ATOM   2012 C C    . CYS A 1 142 ? 83.315  122.205 114.919 1.00 67.56  ? 142 CYS A C    1 
ATOM   2013 O O    . CYS A 1 142 ? 83.608  122.609 113.790 1.00 67.56  ? 142 CYS A O    1 
ATOM   2014 C CB   . CYS A 1 142 ? 81.475  120.646 115.595 1.00 67.56  ? 142 CYS A CB   1 
ATOM   2015 S SG   . CYS A 1 142 ? 80.238  121.272 114.442 1.00 67.56  ? 142 CYS A SG   1 
ATOM   2016 H H    . CYS A 1 142 ? 83.699  120.369 116.908 1.00 67.56  ? 142 CYS A H    1 
ATOM   2017 H HA   . CYS A 1 142 ? 83.006  120.291 114.278 1.00 67.56  ? 142 CYS A HA   1 
ATOM   2018 H HB2  . CYS A 1 142 ? 81.270  119.714 115.763 1.00 67.56  ? 142 CYS A HB2  1 
ATOM   2019 H HB3  . CYS A 1 142 ? 81.380  121.151 116.417 1.00 67.56  ? 142 CYS A HB3  1 
ATOM   2020 N N    . ALA A 1 143 ? 83.311  123.015 115.978 1.00 64.91  ? 143 ALA A N    1 
ATOM   2021 C CA   . ALA A 1 143 ? 83.600  124.436 115.815 1.00 64.91  ? 143 ALA A CA   1 
ATOM   2022 C C    . ALA A 1 143 ? 85.078  124.673 115.541 1.00 64.91  ? 143 ALA A C    1 
ATOM   2023 O O    . ALA A 1 143 ? 85.434  125.485 114.681 1.00 64.91  ? 143 ALA A O    1 
ATOM   2024 C CB   . ALA A 1 143 ? 83.159  125.206 117.058 1.00 64.91  ? 143 ALA A CB   1 
ATOM   2025 H H    . ALA A 1 143 ? 83.147  122.771 116.786 1.00 64.91  ? 143 ALA A H    1 
ATOM   2026 H HA   . ALA A 1 143 ? 83.098  124.776 115.058 1.00 64.91  ? 143 ALA A HA   1 
ATOM   2027 H HB1  . ALA A 1 143 ? 83.370  126.145 116.939 1.00 64.91  ? 143 ALA A HB1  1 
ATOM   2028 H HB2  . ALA A 1 143 ? 82.204  125.092 117.178 1.00 64.91  ? 143 ALA A HB2  1 
ATOM   2029 H HB3  . ALA A 1 143 ? 83.634  124.856 117.828 1.00 64.91  ? 143 ALA A HB3  1 
ATOM   2030 N N    . ASP A 1 144 ? 85.952  123.974 116.260 1.00 57.00  ? 144 ASP A N    1 
ATOM   2031 C CA   . ASP A 1 144 ? 87.389  124.158 116.141 1.00 57.00  ? 144 ASP A CA   1 
ATOM   2032 C C    . ASP A 1 144 ? 88.049  123.077 115.299 1.00 57.00  ? 144 ASP A C    1 
ATOM   2033 O O    . ASP A 1 144 ? 89.273  122.930 115.353 1.00 57.00  ? 144 ASP A O    1 
ATOM   2034 C CB   . ASP A 1 144 ? 88.026  124.192 117.530 1.00 57.00  ? 144 ASP A CB   1 
ATOM   2035 C CG   . ASP A 1 144 ? 87.394  125.226 118.432 1.00 57.00  ? 144 ASP A CG   1 
ATOM   2036 O OD1  . ASP A 1 144 ? 86.416  125.871 117.999 1.00 57.00  ? 144 ASP A OD1  1 
ATOM   2037 O OD2  . ASP A 1 144 ? 87.872  125.395 119.572 1.00 57.00  ? 144 ASP A OD2  1 
ATOM   2038 H H    . ASP A 1 144 ? 85.727  123.375 116.835 1.00 57.00  ? 144 ASP A H    1 
ATOM   2039 H HA   . ASP A 1 144 ? 87.562  125.012 115.716 1.00 57.00  ? 144 ASP A HA   1 
ATOM   2040 H HB2  . ASP A 1 144 ? 87.920  123.323 117.948 1.00 57.00  ? 144 ASP A HB2  1 
ATOM   2041 H HB3  . ASP A 1 144 ? 88.969  124.404 117.441 1.00 57.00  ? 144 ASP A HB3  1 
ATOM   2042 N N    . SER A 1 145 ? 87.269  122.322 114.525 1.00 59.82  ? 145 SER A N    1 
ATOM   2043 C CA   . SER A 1 145 ? 87.789  121.215 113.729 1.00 59.82  ? 145 SER A CA   1 
ATOM   2044 C C    . SER A 1 145 ? 89.107  121.572 113.054 1.00 59.82  ? 145 SER A C    1 
ATOM   2045 O O    . SER A 1 145 ? 89.992  120.722 112.925 1.00 59.82  ? 145 SER A O    1 
ATOM   2046 C CB   . SER A 1 145 ? 86.767  120.794 112.673 1.00 59.82  ? 145 SER A CB   1 
ATOM   2047 O OG   . SER A 1 145 ? 86.491  121.861 111.784 1.00 59.82  ? 145 SER A OG   1 
ATOM   2048 H H    . SER A 1 145 ? 86.420  122.432 114.446 1.00 59.82  ? 145 SER A H    1 
ATOM   2049 H HA   . SER A 1 145 ? 87.947  120.455 114.311 1.00 59.82  ? 145 SER A HA   1 
ATOM   2050 H HB2  . SER A 1 145 ? 87.125  120.047 112.168 1.00 59.82  ? 145 SER A HB2  1 
ATOM   2051 H HB3  . SER A 1 145 ? 85.945  120.532 113.116 1.00 59.82  ? 145 SER A HB3  1 
ATOM   2052 H HG   . SER A 1 145 ? 86.103  122.483 112.196 1.00 59.82  ? 145 SER A HG   1 
ATOM   2053 N N    . TRP A 1 146 ? 89.245  122.824 112.616 1.00 54.99  ? 146 TRP A N    1 
ATOM   2054 C CA   . TRP A 1 146 ? 90.465  123.227 111.927 1.00 54.99  ? 146 TRP A CA   1 
ATOM   2055 C C    . TRP A 1 146 ? 91.702  123.012 112.789 1.00 54.99  ? 146 TRP A C    1 
ATOM   2056 O O    . TRP A 1 146 ? 92.798  122.807 112.256 1.00 54.99  ? 146 TRP A O    1 
ATOM   2057 C CB   . TRP A 1 146 ? 90.369  124.692 111.495 1.00 54.99  ? 146 TRP A CB   1 
ATOM   2058 C CG   . TRP A 1 146 ? 90.140  125.659 112.618 1.00 54.99  ? 146 TRP A CG   1 
ATOM   2059 C CD1  . TRP A 1 146 ? 88.938  126.093 113.092 1.00 54.99  ? 146 TRP A CD1  1 
ATOM   2060 C CD2  . TRP A 1 146 ? 91.141  126.321 113.398 1.00 54.99  ? 146 TRP A CD2  1 
ATOM   2061 N NE1  . TRP A 1 146 ? 89.128  126.982 114.122 1.00 54.99  ? 146 TRP A NE1  1 
ATOM   2062 C CE2  . TRP A 1 146 ? 90.472  127.139 114.329 1.00 54.99  ? 146 TRP A CE2  1 
ATOM   2063 C CE3  . TRP A 1 146 ? 92.537  126.301 113.401 1.00 54.99  ? 146 TRP A CE3  1 
ATOM   2064 C CZ2  . TRP A 1 146 ? 91.151  127.926 115.254 1.00 54.99  ? 146 TRP A CZ2  1 
ATOM   2065 C CZ3  . TRP A 1 146 ? 93.208  127.084 114.320 1.00 54.99  ? 146 TRP A CZ3  1 
ATOM   2066 C CH2  . TRP A 1 146 ? 92.515  127.885 115.233 1.00 54.99  ? 146 TRP A CH2  1 
ATOM   2067 H H    . TRP A 1 146 ? 88.657  123.445 112.703 1.00 54.99  ? 146 TRP A H    1 
ATOM   2068 H HA   . TRP A 1 146 ? 90.564  122.688 111.126 1.00 54.99  ? 146 TRP A HA   1 
ATOM   2069 H HB2  . TRP A 1 146 ? 91.197  124.942 111.057 1.00 54.99  ? 146 TRP A HB2  1 
ATOM   2070 H HB3  . TRP A 1 146 ? 89.630  124.784 110.874 1.00 54.99  ? 146 TRP A HB3  1 
ATOM   2071 H HD1  . TRP A 1 146 ? 88.109  125.826 112.767 1.00 54.99  ? 146 TRP A HD1  1 
ATOM   2072 H HE1  . TRP A 1 146 ? 88.504  127.375 114.566 1.00 54.99  ? 146 TRP A HE1  1 
ATOM   2073 H HE3  . TRP A 1 146 ? 93.005  125.770 112.797 1.00 54.99  ? 146 TRP A HE3  1 
ATOM   2074 H HZ2  . TRP A 1 146 ? 90.693  128.460 115.863 1.00 54.99  ? 146 TRP A HZ2  1 
ATOM   2075 H HZ3  . TRP A 1 146 ? 94.136  127.078 114.331 1.00 54.99  ? 146 TRP A HZ3  1 
ATOM   2076 H HH2  . TRP A 1 146 ? 92.995  128.401 115.840 1.00 54.99  ? 146 TRP A HH2  1 
ATOM   2077 N N    . LYS A 1 147 ? 91.552  123.042 114.114 1.00 53.75  ? 147 LYS A N    1 
ATOM   2078 C CA   . LYS A 1 147 ? 92.720  122.979 114.986 1.00 53.75  ? 147 LYS A CA   1 
ATOM   2079 C C    . LYS A 1 147 ? 93.542  121.715 114.763 1.00 53.75  ? 147 LYS A C    1 
ATOM   2080 O O    . LYS A 1 147 ? 94.765  121.746 114.918 1.00 53.75  ? 147 LYS A O    1 
ATOM   2081 C CB   . LYS A 1 147 ? 92.296  123.071 116.449 1.00 53.75  ? 147 LYS A CB   1 
ATOM   2082 C CG   . LYS A 1 147 ? 91.962  124.477 116.913 1.00 53.75  ? 147 LYS A CG   1 
ATOM   2083 C CD   . LYS A 1 147 ? 91.837  124.529 118.423 1.00 53.75  ? 147 LYS A CD   1 
ATOM   2084 C CE   . LYS A 1 147 ? 91.583  125.936 118.921 1.00 53.75  ? 147 LYS A CE   1 
ATOM   2085 N NZ   . LYS A 1 147 ? 91.634  126.001 120.408 1.00 53.75  ? 147 LYS A NZ   1 
ATOM   2086 H H    . LYS A 1 147 ? 90.798  123.097 114.525 1.00 53.75  ? 147 LYS A H    1 
ATOM   2087 H HA   . LYS A 1 147 ? 93.292  123.740 114.795 1.00 53.75  ? 147 LYS A HA   1 
ATOM   2088 H HB2  . LYS A 1 147 ? 91.507  122.522 116.579 1.00 53.75  ? 147 LYS A HB2  1 
ATOM   2089 H HB3  . LYS A 1 147 ? 93.020  122.742 117.004 1.00 53.75  ? 147 LYS A HB3  1 
ATOM   2090 H HG2  . LYS A 1 147 ? 92.671  125.082 116.642 1.00 53.75  ? 147 LYS A HG2  1 
ATOM   2091 H HG3  . LYS A 1 147 ? 91.117  124.752 116.525 1.00 53.75  ? 147 LYS A HG3  1 
ATOM   2092 H HD2  . LYS A 1 147 ? 91.094  123.971 118.700 1.00 53.75  ? 147 LYS A HD2  1 
ATOM   2093 H HD3  . LYS A 1 147 ? 92.662  124.210 118.823 1.00 53.75  ? 147 LYS A HD3  1 
ATOM   2094 H HE2  . LYS A 1 147 ? 92.262  126.530 118.566 1.00 53.75  ? 147 LYS A HE2  1 
ATOM   2095 H HE3  . LYS A 1 147 ? 90.702  126.223 118.635 1.00 53.75  ? 147 LYS A HE3  1 
ATOM   2096 H HZ1  . LYS A 1 147 ? 91.432  126.823 120.684 1.00 53.75  ? 147 LYS A HZ1  1 
ATOM   2097 H HZ2  . LYS A 1 147 ? 91.051  125.427 120.758 1.00 53.75  ? 147 LYS A HZ2  1 
ATOM   2098 H HZ3  . LYS A 1 147 ? 92.451  125.792 120.693 1.00 53.75  ? 147 LYS A HZ3  1 
ATOM   2099 N N    . VAL A 1 148 ? 92.902  120.594 114.423 1.00 53.60  ? 148 VAL A N    1 
ATOM   2100 C CA   . VAL A 1 148 ? 93.655  119.359 114.208 1.00 53.60  ? 148 VAL A CA   1 
ATOM   2101 C C    . VAL A 1 148 ? 94.588  119.504 113.012 1.00 53.60  ? 148 VAL A C    1 
ATOM   2102 O O    . VAL A 1 148 ? 95.745  119.059 113.044 1.00 53.60  ? 148 VAL A O    1 
ATOM   2103 C CB   . VAL A 1 148 ? 92.695  118.169 114.035 1.00 53.60  ? 148 VAL A CB   1 
ATOM   2104 C CG1  . VAL A 1 148 ? 93.470  116.912 113.684 1.00 53.60  ? 148 VAL A CG1  1 
ATOM   2105 C CG2  . VAL A 1 148 ? 91.885  117.960 115.300 1.00 53.60  ? 148 VAL A CG2  1 
ATOM   2106 H H    . VAL A 1 148 ? 92.052  120.523 114.314 1.00 53.60  ? 148 VAL A H    1 
ATOM   2107 H HA   . VAL A 1 148 ? 94.201  119.186 114.991 1.00 53.60  ? 148 VAL A HA   1 
ATOM   2108 H HB   . VAL A 1 148 ? 92.079  118.359 113.309 1.00 53.60  ? 148 VAL A HB   1 
ATOM   2109 H HG11 . VAL A 1 148 ? 92.892  116.143 113.807 1.00 53.60  ? 148 VAL A HG11 1 
ATOM   2110 H HG12 . VAL A 1 148 ? 93.758  116.962 112.759 1.00 53.60  ? 148 VAL A HG12 1 
ATOM   2111 H HG13 . VAL A 1 148 ? 94.240  116.843 114.269 1.00 53.60  ? 148 VAL A HG13 1 
ATOM   2112 H HG21 . VAL A 1 148 ? 91.309  117.188 115.181 1.00 53.60  ? 148 VAL A HG21 1 
ATOM   2113 H HG22 . VAL A 1 148 ? 92.492  117.808 116.041 1.00 53.60  ? 148 VAL A HG22 1 
ATOM   2114 H HG23 . VAL A 1 148 ? 91.348  118.750 115.467 1.00 53.60  ? 148 VAL A HG23 1 
ATOM   2115 N N    . ASP A 1 149 ? 94.097  120.111 111.931 1.00 55.56  ? 149 ASP A N    1 
ATOM   2116 C CA   . ASP A 1 149 ? 94.966  120.383 110.794 1.00 55.56  ? 149 ASP A CA   1 
ATOM   2117 C C    . ASP A 1 149 ? 96.108  121.303 111.195 1.00 55.56  ? 149 ASP A C    1 
ATOM   2118 O O    . ASP A 1 149 ? 97.241  121.135 110.731 1.00 55.56  ? 149 ASP A O    1 
ATOM   2119 C CB   . ASP A 1 149 ? 94.158  120.990 109.649 1.00 55.56  ? 149 ASP A CB   1 
ATOM   2120 C CG   . ASP A 1 149 ? 93.379  119.949 108.870 1.00 55.56  ? 149 ASP A CG   1 
ATOM   2121 O OD1  . ASP A 1 149 ? 93.550  118.743 109.148 1.00 55.56  ? 149 ASP A OD1  1 
ATOM   2122 O OD2  . ASP A 1 149 ? 92.595  120.335 107.978 1.00 55.56  ? 149 ASP A OD2  1 
ATOM   2123 H H    . ASP A 1 149 ? 93.282  120.368 111.834 1.00 55.56  ? 149 ASP A H    1 
ATOM   2124 H HA   . ASP A 1 149 ? 95.352  119.549 110.483 1.00 55.56  ? 149 ASP A HA   1 
ATOM   2125 H HB2  . ASP A 1 149 ? 93.524  121.628 110.013 1.00 55.56  ? 149 ASP A HB2  1 
ATOM   2126 H HB3  . ASP A 1 149 ? 94.763  121.436 109.035 1.00 55.56  ? 149 ASP A HB3  1 
ATOM   2127 N N    . LEU A 1 150 ? 95.831  122.282 112.058 1.00 50.17  ? 150 LEU A N    1 
ATOM   2128 C CA   . LEU A 1 150 ? 96.895  123.152 112.542 1.00 50.17  ? 150 LEU A CA   1 
ATOM   2129 C C    . LEU A 1 150 ? 97.940  122.357 113.311 1.00 50.17  ? 150 LEU A C    1 
ATOM   2130 O O    . LEU A 1 150 ? 99.141  122.604 113.178 1.00 50.17  ? 150 LEU A O    1 
ATOM   2131 C CB   . LEU A 1 150 ? 96.313  124.257 113.420 1.00 50.17  ? 150 LEU A CB   1 
ATOM   2132 C CG   . LEU A 1 150 ? 97.330  125.257 113.970 1.00 50.17  ? 150 LEU A CG   1 
ATOM   2133 C CD1  . LEU A 1 150 ? 98.022  125.993 112.839 1.00 50.17  ? 150 LEU A CD1  1 
ATOM   2134 C CD2  . LEU A 1 150 ? 96.663  126.241 114.909 1.00 50.17  ? 150 LEU A CD2  1 
ATOM   2135 H H    . LEU A 1 150 ? 95.050  122.458 112.371 1.00 50.17  ? 150 LEU A H    1 
ATOM   2136 H HA   . LEU A 1 150 ? 97.332  123.566 111.782 1.00 50.17  ? 150 LEU A HA   1 
ATOM   2137 H HB2  . LEU A 1 150 ? 95.666  124.756 112.897 1.00 50.17  ? 150 LEU A HB2  1 
ATOM   2138 H HB3  . LEU A 1 150 ? 95.869  123.846 114.178 1.00 50.17  ? 150 LEU A HB3  1 
ATOM   2139 H HG   . LEU A 1 150 ? 98.007  124.779 114.475 1.00 50.17  ? 150 LEU A HG   1 
ATOM   2140 H HD11 . LEU A 1 150 ? 98.575  126.695 113.214 1.00 50.17  ? 150 LEU A HD11 1 
ATOM   2141 H HD12 . LEU A 1 150 ? 98.572  125.367 112.343 1.00 50.17  ? 150 LEU A HD12 1 
ATOM   2142 H HD13 . LEU A 1 150 ? 97.349  126.378 112.256 1.00 50.17  ? 150 LEU A HD13 1 
ATOM   2143 H HD21 . LEU A 1 150 ? 97.348  126.730 115.391 1.00 50.17  ? 150 LEU A HD21 1 
ATOM   2144 H HD22 . LEU A 1 150 ? 96.125  126.856 114.388 1.00 50.17  ? 150 LEU A HD22 1 
ATOM   2145 H HD23 . LEU A 1 150 ? 96.103  125.754 115.534 1.00 50.17  ? 150 LEU A HD23 1 
ATOM   2146 N N    . PHE A 1 151 ? 97.497  121.403 114.128 1.00 48.89  ? 151 PHE A N    1 
ATOM   2147 C CA   . PHE A 1 151 ? 98.425  120.557 114.872 1.00 48.89  ? 151 PHE A CA   1 
ATOM   2148 C C    . PHE A 1 151 ? 99.315  119.762 113.925 1.00 48.89  ? 151 PHE A C    1 
ATOM   2149 O O    . PHE A 1 151 ? 100.542 119.710 114.092 1.00 48.89  ? 151 PHE A O    1 
ATOM   2150 C CB   . PHE A 1 151 ? 97.628  119.624 115.784 1.00 48.89  ? 151 PHE A CB   1 
ATOM   2151 C CG   . PHE A 1 151 ? 98.467  118.802 116.712 1.00 48.89  ? 151 PHE A CG   1 
ATOM   2152 C CD1  . PHE A 1 151 ? 99.023  117.608 116.293 1.00 48.89  ? 151 PHE A CD1  1 
ATOM   2153 C CD2  . PHE A 1 151 ? 98.671  119.207 118.016 1.00 48.89  ? 151 PHE A CD2  1 
ATOM   2154 C CE1  . PHE A 1 151 ? 99.782  116.847 117.151 1.00 48.89  ? 151 PHE A CE1  1 
ATOM   2155 C CE2  . PHE A 1 151 ? 99.428  118.450 118.877 1.00 48.89  ? 151 PHE A CE2  1 
ATOM   2156 C CZ   . PHE A 1 151 ? 99.983  117.267 118.445 1.00 48.89  ? 151 PHE A CZ   1 
ATOM   2157 H H    . PHE A 1 151 ? 96.667  121.225 114.267 1.00 48.89  ? 151 PHE A H    1 
ATOM   2158 H HA   . PHE A 1 151 ? 98.993  121.114 115.427 1.00 48.89  ? 151 PHE A HA   1 
ATOM   2159 H HB2  . PHE A 1 151 ? 97.027  120.159 116.326 1.00 48.89  ? 151 PHE A HB2  1 
ATOM   2160 H HB3  . PHE A 1 151 ? 97.114  119.014 115.232 1.00 48.89  ? 151 PHE A HB3  1 
ATOM   2161 H HD1  . PHE A 1 151 ? 98.889  117.320 115.419 1.00 48.89  ? 151 PHE A HD1  1 
ATOM   2162 H HD2  . PHE A 1 151 ? 98.297  120.005 118.312 1.00 48.89  ? 151 PHE A HD2  1 
ATOM   2163 H HE1  . PHE A 1 151 ? 100.157 116.048 116.858 1.00 48.89  ? 151 PHE A HE1  1 
ATOM   2164 H HE2  . PHE A 1 151 ? 99.564  118.736 119.751 1.00 48.89  ? 151 PHE A HE2  1 
ATOM   2165 H HZ   . PHE A 1 151 ? 100.497 116.755 119.027 1.00 48.89  ? 151 PHE A HZ   1 
ATOM   2166 N N    . GLN A 1 152 ? 98.709  119.135 112.916 1.00 51.86  ? 152 GLN A N    1 
ATOM   2167 C CA   . GLN A 1 152 ? 99.497  118.360 111.963 1.00 51.86  ? 152 GLN A CA   1 
ATOM   2168 C C    . GLN A 1 152 ? 100.488 119.249 111.221 1.00 51.86  ? 152 GLN A C    1 
ATOM   2169 O O    . GLN A 1 152 ? 101.654 118.875 111.032 1.00 51.86  ? 152 GLN A O    1 
ATOM   2170 C CB   . GLN A 1 152 ? 98.577  117.646 110.975 1.00 51.86  ? 152 GLN A CB   1 
ATOM   2171 C CG   . GLN A 1 152 ? 99.312  116.798 109.949 1.00 51.86  ? 152 GLN A CG   1 
ATOM   2172 C CD   . GLN A 1 152 ? 98.372  116.105 108.983 1.00 51.86  ? 152 GLN A CD   1 
ATOM   2173 O OE1  . GLN A 1 152 ? 97.429  115.429 109.393 1.00 51.86  ? 152 GLN A OE1  1 
ATOM   2174 N NE2  . GLN A 1 152 ? 98.622  116.275 107.690 1.00 51.86  ? 152 GLN A NE2  1 
ATOM   2175 H H    . GLN A 1 152 ? 97.862  119.142 112.765 1.00 51.86  ? 152 GLN A H    1 
ATOM   2176 H HA   . GLN A 1 152 ? 100.001 117.686 112.444 1.00 51.86  ? 152 GLN A HA   1 
ATOM   2177 H HB2  . GLN A 1 152 ? 97.981  117.061 111.470 1.00 51.86  ? 152 GLN A HB2  1 
ATOM   2178 H HB3  . GLN A 1 152 ? 98.059  118.310 110.494 1.00 51.86  ? 152 GLN A HB3  1 
ATOM   2179 H HG2  . GLN A 1 152 ? 99.906  117.363 109.431 1.00 51.86  ? 152 GLN A HG2  1 
ATOM   2180 H HG3  . GLN A 1 152 ? 99.823  116.115 110.411 1.00 51.86  ? 152 GLN A HG3  1 
ATOM   2181 H HE21 . GLN A 1 152 ? 99.290  116.756 107.440 1.00 51.86  ? 152 GLN A HE21 1 
ATOM   2182 H HE22 . GLN A 1 152 ? 98.116  115.903 107.102 1.00 51.86  ? 152 GLN A HE22 1 
ATOM   2183 N N    . SER A 1 153 ? 100.046 120.433 110.794 1.00 52.56  ? 153 SER A N    1 
ATOM   2184 C CA   . SER A 1 153 ? 100.933 121.337 110.070 1.00 52.56  ? 153 SER A CA   1 
ATOM   2185 C C    . SER A 1 153 ? 102.070 121.820 110.958 1.00 52.56  ? 153 SER A C    1 
ATOM   2186 O O    . SER A 1 153 ? 103.202 121.976 110.492 1.00 52.56  ? 153 SER A O    1 
ATOM   2187 C CB   . SER A 1 153 ? 100.145 122.525 109.528 1.00 52.56  ? 153 SER A CB   1 
ATOM   2188 O OG   . SER A 1 153 ? 99.801  123.414 110.575 1.00 52.56  ? 153 SER A OG   1 
ATOM   2189 H H    . SER A 1 153 ? 99.247  120.731 110.909 1.00 52.56  ? 153 SER A H    1 
ATOM   2190 H HA   . SER A 1 153 ? 101.320 120.864 109.317 1.00 52.56  ? 153 SER A HA   1 
ATOM   2191 H HB2  . SER A 1 153 ? 100.689 122.996 108.878 1.00 52.56  ? 153 SER A HB2  1 
ATOM   2192 H HB3  . SER A 1 153 ? 99.333  122.200 109.109 1.00 52.56  ? 153 SER A HB3  1 
ATOM   2193 H HG   . SER A 1 153 ? 99.348  123.010 111.156 1.00 52.56  ? 153 SER A HG   1 
ATOM   2194 N N    . CYS A 1 154 ? 101.786 122.088 112.233 1.00 49.01  ? 154 CYS A N    1 
ATOM   2195 C CA   . CYS A 1 154 ? 102.842 122.495 113.152 1.00 49.01  ? 154 CYS A CA   1 
ATOM   2196 C C    . CYS A 1 154 ? 103.867 121.385 113.333 1.00 49.01  ? 154 CYS A C    1 
ATOM   2197 O O    . CYS A 1 154 ? 105.076 121.641 113.336 1.00 49.01  ? 154 CYS A O    1 
ATOM   2198 C CB   . CYS A 1 154 ? 102.241 122.897 114.496 1.00 49.01  ? 154 CYS A CB   1 
ATOM   2199 S SG   . CYS A 1 154 ? 101.427 124.507 114.479 1.00 49.01  ? 154 CYS A SG   1 
ATOM   2200 H H    . CYS A 1 154 ? 101.002 122.043 112.584 1.00 49.01  ? 154 CYS A H    1 
ATOM   2201 H HA   . CYS A 1 154 ? 103.294 123.270 112.786 1.00 49.01  ? 154 CYS A HA   1 
ATOM   2202 H HB2  . CYS A 1 154 ? 101.581 122.234 114.752 1.00 49.01  ? 154 CYS A HB2  1 
ATOM   2203 H HB3  . CYS A 1 154 ? 102.949 122.929 115.159 1.00 49.01  ? 154 CYS A HB3  1 
ATOM   2204 H HG   . CYS A 1 154 ? 100.553 124.505 113.657 1.00 49.01  ? 154 CYS A HG   1 
ATOM   2205 N N    . VAL A 1 155 ? 103.411 120.140 113.471 1.00 49.42  ? 155 VAL A N    1 
ATOM   2206 C CA   . VAL A 1 155 ? 104.359 119.035 113.583 1.00 49.42  ? 155 VAL A CA   1 
ATOM   2207 C C    . VAL A 1 155 ? 105.211 118.938 112.323 1.00 49.42  ? 155 VAL A C    1 
ATOM   2208 O O    . VAL A 1 155 ? 106.429 118.730 112.393 1.00 49.42  ? 155 VAL A O    1 
ATOM   2209 C CB   . VAL A 1 155 ? 103.619 117.716 113.868 1.00 49.42  ? 155 VAL A CB   1 
ATOM   2210 C CG1  . VAL A 1 155 ? 104.577 116.538 113.775 1.00 49.42  ? 155 VAL A CG1  1 
ATOM   2211 C CG2  . VAL A 1 155 ? 102.972 117.765 115.237 1.00 49.42  ? 155 VAL A CG2  1 
ATOM   2212 H H    . VAL A 1 155 ? 102.581 119.915 113.503 1.00 49.42  ? 155 VAL A H    1 
ATOM   2213 H HA   . VAL A 1 155 ? 104.953 119.207 114.329 1.00 49.42  ? 155 VAL A HA   1 
ATOM   2214 H HB   . VAL A 1 155 ? 102.920 117.591 113.206 1.00 49.42  ? 155 VAL A HB   1 
ATOM   2215 H HG11 . VAL A 1 155 ? 104.167 115.766 114.196 1.00 49.42  ? 155 VAL A HG11 1 
ATOM   2216 H HG12 . VAL A 1 155 ? 104.758 116.345 112.841 1.00 49.42  ? 155 VAL A HG12 1 
ATOM   2217 H HG13 . VAL A 1 155 ? 105.400 116.764 114.235 1.00 49.42  ? 155 VAL A HG13 1 
ATOM   2218 H HG21 . VAL A 1 155 ? 102.509 116.929 115.399 1.00 49.42  ? 155 VAL A HG21 1 
ATOM   2219 H HG22 . VAL A 1 155 ? 103.663 117.898 115.905 1.00 49.42  ? 155 VAL A HG22 1 
ATOM   2220 H HG23 . VAL A 1 155 ? 102.343 118.503 115.262 1.00 49.42  ? 155 VAL A HG23 1 
ATOM   2221 N N    . ASN A 1 156 ? 104.588 119.079 111.150 1.00 52.07  ? 156 ASN A N    1 
ATOM   2222 C CA   . ASN A 1 156 ? 105.343 118.945 109.906 1.00 52.07  ? 156 ASN A CA   1 
ATOM   2223 C C    . ASN A 1 156 ? 106.348 120.079 109.730 1.00 52.07  ? 156 ASN A C    1 
ATOM   2224 O O    . ASN A 1 156 ? 107.479 119.848 109.287 1.00 52.07  ? 156 ASN A O    1 
ATOM   2225 C CB   . ASN A 1 156 ? 104.391 118.877 108.716 1.00 52.07  ? 156 ASN A CB   1 
ATOM   2226 C CG   . ASN A 1 156 ? 103.781 117.505 108.544 1.00 52.07  ? 156 ASN A CG   1 
ATOM   2227 O OD1  . ASN A 1 156 ? 103.595 116.771 109.513 1.00 52.07  ? 156 ASN A OD1  1 
ATOM   2228 N ND2  . ASN A 1 156 ? 103.480 117.143 107.305 1.00 52.07  ? 156 ASN A ND2  1 
ATOM   2229 H H    . ASN A 1 156 ? 103.751 119.247 111.050 1.00 52.07  ? 156 ASN A H    1 
ATOM   2230 H HA   . ASN A 1 156 ? 105.840 118.112 109.934 1.00 52.07  ? 156 ASN A HA   1 
ATOM   2231 H HB2  . ASN A 1 156 ? 103.673 119.516 108.842 1.00 52.07  ? 156 ASN A HB2  1 
ATOM   2232 H HB3  . ASN A 1 156 ? 104.886 119.082 107.910 1.00 52.07  ? 156 ASN A HB3  1 
ATOM   2233 H HD21 . ASN A 1 156 ? 103.132 116.371 107.155 1.00 52.07  ? 156 ASN A HD21 1 
ATOM   2234 H HD22 . ASN A 1 156 ? 103.627 117.683 106.652 1.00 52.07  ? 156 ASN A HD22 1 
ATOM   2235 N N    . VAL A 1 157 ? 105.964 121.313 110.062 1.00 49.10  ? 157 VAL A N    1 
ATOM   2236 C CA   . VAL A 1 157 ? 106.919 122.411 109.948 1.00 49.10  ? 157 VAL A CA   1 
ATOM   2237 C C    . VAL A 1 157 ? 108.024 122.250 110.981 1.00 49.10  ? 157 VAL A C    1 
ATOM   2238 O O    . VAL A 1 157 ? 109.169 122.654 110.744 1.00 49.10  ? 157 VAL A O    1 
ATOM   2239 C CB   . VAL A 1 157 ? 106.214 123.774 110.076 1.00 49.10  ? 157 VAL A CB   1 
ATOM   2240 C CG1  . VAL A 1 157 ? 105.744 124.008 111.491 1.00 49.10  ? 157 VAL A CG1  1 
ATOM   2241 C CG2  . VAL A 1 157 ? 107.138 124.891 109.628 1.00 49.10  ? 157 VAL A CG2  1 
ATOM   2242 H H    . VAL A 1 157 ? 105.183 121.533 110.346 1.00 49.10  ? 157 VAL A H    1 
ATOM   2243 H HA   . VAL A 1 157 ? 107.330 122.374 109.070 1.00 49.10  ? 157 VAL A HA   1 
ATOM   2244 H HB   . VAL A 1 157 ? 105.435 123.780 109.498 1.00 49.10  ? 157 VAL A HB   1 
ATOM   2245 H HG11 . VAL A 1 157 ? 105.202 124.812 111.512 1.00 49.10  ? 157 VAL A HG11 1 
ATOM   2246 H HG12 . VAL A 1 157 ? 105.215 123.248 111.764 1.00 49.10  ? 157 VAL A HG12 1 
ATOM   2247 H HG13 . VAL A 1 157 ? 106.512 124.112 112.075 1.00 49.10  ? 157 VAL A HG13 1 
ATOM   2248 H HG21 . VAL A 1 157 ? 106.662 125.734 109.683 1.00 49.10  ? 157 VAL A HG21 1 
ATOM   2249 H HG22 . VAL A 1 157 ? 107.915 124.911 110.208 1.00 49.10  ? 157 VAL A HG22 1 
ATOM   2250 H HG23 . VAL A 1 157 ? 107.412 124.725 108.712 1.00 49.10  ? 157 VAL A HG23 1 
ATOM   2251 N N    . GLY A 1 158 ? 107.712 121.660 112.134 1.00 47.87  ? 158 GLY A N    1 
ATOM   2252 C CA   . GLY A 1 158 ? 108.764 121.323 113.074 1.00 47.87  ? 158 GLY A CA   1 
ATOM   2253 C C    . GLY A 1 158 ? 109.753 120.335 112.489 1.00 47.87  ? 158 GLY A C    1 
ATOM   2254 O O    . GLY A 1 158 ? 110.965 120.503 112.625 1.00 47.87  ? 158 GLY A O    1 
ATOM   2255 H H    . GLY A 1 158 ? 106.917 121.449 112.387 1.00 47.87  ? 158 GLY A H    1 
ATOM   2256 H HA2  . GLY A 1 158 ? 109.242 122.127 113.327 1.00 47.87  ? 158 GLY A HA2  1 
ATOM   2257 H HA3  . GLY A 1 158 ? 108.374 120.930 113.870 1.00 47.87  ? 158 GLY A HA3  1 
ATOM   2258 N N    . PHE A 1 159 ? 109.247 119.289 111.834 1.00 45.48  ? 159 PHE A N    1 
ATOM   2259 C CA   . PHE A 1 159 ? 110.124 118.376 111.106 1.00 45.48  ? 159 PHE A CA   1 
ATOM   2260 C C    . PHE A 1 159 ? 111.002 119.142 110.129 1.00 45.48  ? 159 PHE A C    1 
ATOM   2261 O O    . PHE A 1 159 ? 112.218 118.931 110.061 1.00 45.48  ? 159 PHE A O    1 
ATOM   2262 C CB   . PHE A 1 159 ? 109.299 117.336 110.343 1.00 45.48  ? 159 PHE A CB   1 
ATOM   2263 C CG   . PHE A 1 159 ? 109.023 116.067 111.104 1.00 45.48  ? 159 PHE A CG   1 
ATOM   2264 C CD1  . PHE A 1 159 ? 109.391 115.910 112.428 1.00 45.48  ? 159 PHE A CD1  1 
ATOM   2265 C CD2  . PHE A 1 159 ? 108.391 115.017 110.468 1.00 45.48  ? 159 PHE A CD2  1 
ATOM   2266 C CE1  . PHE A 1 159 ? 109.126 114.735 113.095 1.00 45.48  ? 159 PHE A CE1  1 
ATOM   2267 C CE2  . PHE A 1 159 ? 108.126 113.845 111.130 1.00 45.48  ? 159 PHE A CE2  1 
ATOM   2268 C CZ   . PHE A 1 159 ? 108.494 113.703 112.444 1.00 45.48  ? 159 PHE A CZ   1 
ATOM   2269 H H    . PHE A 1 159 ? 108.411 119.087 111.799 1.00 45.48  ? 159 PHE A H    1 
ATOM   2270 H HA   . PHE A 1 159 ? 110.723 117.937 111.726 1.00 45.48  ? 159 PHE A HA   1 
ATOM   2271 H HB2  . PHE A 1 159 ? 108.444 117.727 110.107 1.00 45.48  ? 159 PHE A HB2  1 
ATOM   2272 H HB3  . PHE A 1 159 ? 109.779 117.092 109.537 1.00 45.48  ? 159 PHE A HB3  1 
ATOM   2273 H HD1  . PHE A 1 159 ? 109.818 116.601 112.878 1.00 45.48  ? 159 PHE A HD1  1 
ATOM   2274 H HD2  . PHE A 1 159 ? 108.138 115.106 109.577 1.00 45.48  ? 159 PHE A HD2  1 
ATOM   2275 H HE1  . PHE A 1 159 ? 109.375 114.638 113.985 1.00 45.48  ? 159 PHE A HE1  1 
ATOM   2276 H HE2  . PHE A 1 159 ? 107.698 113.148 110.689 1.00 45.48  ? 159 PHE A HE2  1 
ATOM   2277 H HZ   . PHE A 1 159 ? 108.314 112.909 112.893 1.00 45.48  ? 159 PHE A HZ   1 
ATOM   2278 N N    . PHE A 1 160 ? 110.388 120.030 109.348 1.00 47.90  ? 160 PHE A N    1 
ATOM   2279 C CA   . PHE A 1 160 ? 111.125 120.729 108.302 1.00 47.90  ? 160 PHE A CA   1 
ATOM   2280 C C    . PHE A 1 160 ? 112.256 121.562 108.890 1.00 47.90  ? 160 PHE A C    1 
ATOM   2281 O O    . PHE A 1 160 ? 113.395 121.507 108.415 1.00 47.90  ? 160 PHE A O    1 
ATOM   2282 C CB   . PHE A 1 160 ? 110.173 121.608 107.494 1.00 47.90  ? 160 PHE A CB   1 
ATOM   2283 C CG   . PHE A 1 160 ? 110.843 122.373 106.396 1.00 47.90  ? 160 PHE A CG   1 
ATOM   2284 C CD1  . PHE A 1 160 ? 111.000 121.815 105.141 1.00 47.90  ? 160 PHE A CD1  1 
ATOM   2285 C CD2  . PHE A 1 160 ? 111.314 123.654 106.616 1.00 47.90  ? 160 PHE A CD2  1 
ATOM   2286 C CE1  . PHE A 1 160 ? 111.616 122.518 104.129 1.00 47.90  ? 160 PHE A CE1  1 
ATOM   2287 C CE2  . PHE A 1 160 ? 111.931 124.361 105.607 1.00 47.90  ? 160 PHE A CE2  1 
ATOM   2288 C CZ   . PHE A 1 160 ? 112.082 123.793 104.362 1.00 47.90  ? 160 PHE A CZ   1 
ATOM   2289 H H    . PHE A 1 160 ? 109.557 120.242 109.403 1.00 47.90  ? 160 PHE A H    1 
ATOM   2290 H HA   . PHE A 1 160 ? 111.515 120.076 107.700 1.00 47.90  ? 160 PHE A HA   1 
ATOM   2291 H HB2  . PHE A 1 160 ? 109.494 121.044 107.091 1.00 47.90  ? 160 PHE A HB2  1 
ATOM   2292 H HB3  . PHE A 1 160 ? 109.756 122.248 108.092 1.00 47.90  ? 160 PHE A HB3  1 
ATOM   2293 H HD1  . PHE A 1 160 ? 110.687 120.954 104.979 1.00 47.90  ? 160 PHE A HD1  1 
ATOM   2294 H HD2  . PHE A 1 160 ? 111.215 124.041 107.454 1.00 47.90  ? 160 PHE A HD2  1 
ATOM   2295 H HE1  . PHE A 1 160 ? 111.717 122.132 103.289 1.00 47.90  ? 160 PHE A HE1  1 
ATOM   2296 H HE2  . PHE A 1 160 ? 112.244 125.222 105.767 1.00 47.90  ? 160 PHE A HE2  1 
ATOM   2297 H HZ   . PHE A 1 160 ? 112.497 124.269 103.680 1.00 47.90  ? 160 PHE A HZ   1 
ATOM   2298 N N    . LEU A 1 161 ? 111.961 122.345 109.928 1.00 46.62  ? 161 LEU A N    1 
ATOM   2299 C CA   . LEU A 1 161 ? 113.005 123.165 110.539 1.00 46.62  ? 161 LEU A CA   1 
ATOM   2300 C C    . LEU A 1 161 ? 114.073 122.300 111.197 1.00 46.62  ? 161 LEU A C    1 
ATOM   2301 O O    . LEU A 1 161 ? 115.273 122.562 111.049 1.00 46.62  ? 161 LEU A O    1 
ATOM   2302 C CB   . LEU A 1 161 ? 112.398 124.131 111.556 1.00 46.62  ? 161 LEU A CB   1 
ATOM   2303 C CG   . LEU A 1 161 ? 112.127 125.553 111.058 1.00 46.62  ? 161 LEU A CG   1 
ATOM   2304 C CD1  . LEU A 1 161 ? 113.424 126.263 110.710 1.00 46.62  ? 161 LEU A CD1  1 
ATOM   2305 C CD2  . LEU A 1 161 ? 111.198 125.535 109.862 1.00 46.62  ? 161 LEU A CD2  1 
ATOM   2306 H H    . LEU A 1 161 ? 111.184 122.418 110.289 1.00 46.62  ? 161 LEU A H    1 
ATOM   2307 H HA   . LEU A 1 161 ? 113.434 123.687 109.844 1.00 46.62  ? 161 LEU A HA   1 
ATOM   2308 H HB2  . LEU A 1 161 ? 111.553 123.765 111.861 1.00 46.62  ? 161 LEU A HB2  1 
ATOM   2309 H HB3  . LEU A 1 161 ? 113.008 124.202 112.307 1.00 46.62  ? 161 LEU A HB3  1 
ATOM   2310 H HG   . LEU A 1 161 ? 111.691 126.056 111.765 1.00 46.62  ? 161 LEU A HG   1 
ATOM   2311 H HD11 . LEU A 1 161 ? 113.239 127.205 110.565 1.00 46.62  ? 161 LEU A HD11 1 
ATOM   2312 H HD12 . LEU A 1 161 ? 114.049 126.158 111.445 1.00 46.62  ? 161 LEU A HD12 1 
ATOM   2313 H HD13 . LEU A 1 161 ? 113.794 125.872 109.904 1.00 46.62  ? 161 LEU A HD13 1 
ATOM   2314 H HD21 . LEU A 1 161 ? 110.927 126.444 109.660 1.00 46.62  ? 161 LEU A HD21 1 
ATOM   2315 H HD22 . LEU A 1 161 ? 111.669 125.155 109.105 1.00 46.62  ? 161 LEU A HD22 1 
ATOM   2316 H HD23 . LEU A 1 161 ? 110.419 124.997 110.074 1.00 46.62  ? 161 LEU A HD23 1 
ATOM   2317 N N    . GLY A 1 162 ? 113.661 121.261 111.924 1.00 46.63  ? 162 GLY A N    1 
ATOM   2318 C CA   . GLY A 1 162 ? 114.629 120.420 112.604 1.00 46.63  ? 162 GLY A CA   1 
ATOM   2319 C C    . GLY A 1 162 ? 115.574 119.732 111.643 1.00 46.63  ? 162 GLY A C    1 
ATOM   2320 O O    . GLY A 1 162 ? 116.749 119.525 111.956 1.00 46.63  ? 162 GLY A O    1 
ATOM   2321 H H    . GLY A 1 162 ? 112.840 121.031 112.039 1.00 46.63  ? 162 GLY A H    1 
ATOM   2322 H HA2  . GLY A 1 162 ? 115.152 120.959 113.217 1.00 46.63  ? 162 GLY A HA2  1 
ATOM   2323 H HA3  . GLY A 1 162 ? 114.164 119.737 113.112 1.00 46.63  ? 162 GLY A HA3  1 
ATOM   2324 N N    . SER A 1 163 ? 115.078 119.365 110.463 1.00 45.97  ? 163 SER A N    1 
ATOM   2325 C CA   . SER A 1 163 ? 115.947 118.738 109.477 1.00 45.97  ? 163 SER A CA   1 
ATOM   2326 C C    . SER A 1 163 ? 117.183 119.592 109.233 1.00 45.97  ? 163 SER A C    1 
ATOM   2327 O O    . SER A 1 163 ? 118.316 119.115 109.348 1.00 45.97  ? 163 SER A O    1 
ATOM   2328 C CB   . SER A 1 163 ? 115.179 118.519 108.176 1.00 45.97  ? 163 SER A CB   1 
ATOM   2329 O OG   . SER A 1 163 ? 113.969 117.814 108.408 1.00 45.97  ? 163 SER A OG   1 
ATOM   2330 H H    . SER A 1 163 ? 114.261 119.464 110.215 1.00 45.97  ? 163 SER A H    1 
ATOM   2331 H HA   . SER A 1 163 ? 116.243 117.878 109.815 1.00 45.97  ? 163 SER A HA   1 
ATOM   2332 H HB2  . SER A 1 163 ? 114.977 119.388 107.794 1.00 45.97  ? 163 SER A HB2  1 
ATOM   2333 H HB3  . SER A 1 163 ? 115.732 118.011 107.562 1.00 45.97  ? 163 SER A HB3  1 
ATOM   2334 H HG   . SER A 1 163 ? 113.401 117.997 107.814 1.00 45.97  ? 163 SER A HG   1 
ATOM   2335 N N    . LEU A 1 164 ? 116.982 120.873 108.922 1.00 48.91  ? 164 LEU A N    1 
ATOM   2336 C CA   . LEU A 1 164 ? 118.116 121.762 108.703 1.00 48.91  ? 164 LEU A CA   1 
ATOM   2337 C C    . LEU A 1 164 ? 118.885 122.017 109.992 1.00 48.91  ? 164 LEU A C    1 
ATOM   2338 O O    . LEU A 1 164 ? 120.120 122.036 109.991 1.00 48.91  ? 164 LEU A O    1 
ATOM   2339 C CB   . LEU A 1 164 ? 117.632 123.078 108.097 1.00 48.91  ? 164 LEU A CB   1 
ATOM   2340 C CG   . LEU A 1 164 ? 117.112 122.979 106.662 1.00 48.91  ? 164 LEU A CG   1 
ATOM   2341 C CD1  . LEU A 1 164 ? 116.529 124.304 106.200 1.00 48.91  ? 164 LEU A CD1  1 
ATOM   2342 C CD2  . LEU A 1 164 ? 118.229 122.533 105.735 1.00 48.91  ? 164 LEU A CD2  1 
ATOM   2343 H H    . LEU A 1 164 ? 116.213 121.246 108.832 1.00 48.91  ? 164 LEU A H    1 
ATOM   2344 H HA   . LEU A 1 164 ? 118.730 121.347 108.077 1.00 48.91  ? 164 LEU A HA   1 
ATOM   2345 H HB2  . LEU A 1 164 ? 116.907 123.418 108.644 1.00 48.91  ? 164 LEU A HB2  1 
ATOM   2346 H HB3  . LEU A 1 164 ? 118.365 123.713 108.099 1.00 48.91  ? 164 LEU A HB3  1 
ATOM   2347 H HG   . LEU A 1 164 ? 116.408 122.312 106.624 1.00 48.91  ? 164 LEU A HG   1 
ATOM   2348 H HD11 . LEU A 1 164 ? 116.276 124.231 105.267 1.00 48.91  ? 164 LEU A HD11 1 
ATOM   2349 H HD12 . LEU A 1 164 ? 115.749 124.510 106.739 1.00 48.91  ? 164 LEU A HD12 1 
ATOM   2350 H HD13 . LEU A 1 164 ? 117.200 124.996 106.307 1.00 48.91  ? 164 LEU A HD13 1 
ATOM   2351 H HD21 . LEU A 1 164 ? 117.983 122.729 104.818 1.00 48.91  ? 164 LEU A HD21 1 
ATOM   2352 H HD22 . LEU A 1 164 ? 119.039 123.012 105.971 1.00 48.91  ? 164 LEU A HD22 1 
ATOM   2353 H HD23 . LEU A 1 164 ? 118.368 121.580 105.845 1.00 48.91  ? 164 LEU A HD23 1 
ATOM   2354 N N    . GLY A 1 165 ? 118.175 122.219 111.103 1.00 52.31  ? 165 GLY A N    1 
ATOM   2355 C CA   . GLY A 1 165 ? 118.843 122.653 112.320 1.00 52.31  ? 165 GLY A CA   1 
ATOM   2356 C C    . GLY A 1 165 ? 119.765 121.605 112.916 1.00 52.31  ? 165 GLY A C    1 
ATOM   2357 O O    . GLY A 1 165 ? 120.895 121.911 113.305 1.00 52.31  ? 165 GLY A O    1 
ATOM   2358 H H    . GLY A 1 165 ? 117.326 122.108 111.176 1.00 52.31  ? 165 GLY A H    1 
ATOM   2359 H HA2  . GLY A 1 165 ? 119.374 123.440 112.123 1.00 52.31  ? 165 GLY A HA2  1 
ATOM   2360 H HA3  . GLY A 1 165 ? 118.180 122.895 112.985 1.00 52.31  ? 165 GLY A HA3  1 
ATOM   2361 N N    . VAL A 1 166 ? 119.302 120.356 112.996 1.00 50.06  ? 166 VAL A N    1 
ATOM   2362 C CA   . VAL A 1 166 ? 120.033 119.351 113.756 1.00 50.06  ? 166 VAL A CA   1 
ATOM   2363 C C    . VAL A 1 166 ? 121.316 118.921 113.060 1.00 50.06  ? 166 VAL A C    1 
ATOM   2364 O O    . VAL A 1 166 ? 122.236 118.426 113.720 1.00 50.06  ? 166 VAL A O    1 
ATOM   2365 C CB   . VAL A 1 166 ? 119.140 118.127 114.025 1.00 50.06  ? 166 VAL A CB   1 
ATOM   2366 C CG1  . VAL A 1 166 ? 118.867 117.380 112.735 1.00 50.06  ? 166 VAL A CG1  1 
ATOM   2367 C CG2  . VAL A 1 166 ? 119.795 117.214 115.047 1.00 50.06  ? 166 VAL A CG2  1 
ATOM   2368 H H    . VAL A 1 166 ? 118.581 120.072 112.622 1.00 50.06  ? 166 VAL A H    1 
ATOM   2369 H HA   . VAL A 1 166 ? 120.275 119.731 114.615 1.00 50.06  ? 166 VAL A HA   1 
ATOM   2370 H HB   . VAL A 1 166 ? 118.291 118.425 114.387 1.00 50.06  ? 166 VAL A HB   1 
ATOM   2371 H HG11 . VAL A 1 166 ? 118.103 116.797 112.864 1.00 50.06  ? 166 VAL A HG11 1 
ATOM   2372 H HG12 . VAL A 1 166 ? 118.679 118.020 112.031 1.00 50.06  ? 166 VAL A HG12 1 
ATOM   2373 H HG13 . VAL A 1 166 ? 119.649 116.857 112.504 1.00 50.06  ? 166 VAL A HG13 1 
ATOM   2374 H HG21 . VAL A 1 166 ? 119.153 116.545 115.329 1.00 50.06  ? 166 VAL A HG21 1 
ATOM   2375 H HG22 . VAL A 1 166 ? 120.564 116.784 114.641 1.00 50.06  ? 166 VAL A HG22 1 
ATOM   2376 H HG23 . VAL A 1 166 ? 120.075 117.744 115.809 1.00 50.06  ? 166 VAL A HG23 1 
ATOM   2377 N N    . GLY A 1 167 ? 121.411 119.093 111.742 1.00 50.24  ? 167 GLY A N    1 
ATOM   2378 C CA   . GLY A 1 167 ? 122.579 118.594 111.034 1.00 50.24  ? 167 GLY A CA   1 
ATOM   2379 C C    . GLY A 1 167 ? 123.868 119.246 111.497 1.00 50.24  ? 167 GLY A C    1 
ATOM   2380 O O    . GLY A 1 167 ? 124.868 118.568 111.751 1.00 50.24  ? 167 GLY A O    1 
ATOM   2381 H H    . GLY A 1 167 ? 120.827 119.486 111.249 1.00 50.24  ? 167 GLY A H    1 
ATOM   2382 H HA2  . GLY A 1 167 ? 122.654 117.637 111.168 1.00 50.24  ? 167 GLY A HA2  1 
ATOM   2383 H HA3  . GLY A 1 167 ? 122.476 118.765 110.085 1.00 50.24  ? 167 GLY A HA3  1 
ATOM   2384 N N    . TYR A 1 168 ? 123.863 120.575 111.616 1.00 53.85  ? 168 TYR A N    1 
ATOM   2385 C CA   . TYR A 1 168 ? 125.094 121.273 111.965 1.00 53.85  ? 168 TYR A CA   1 
ATOM   2386 C C    . TYR A 1 168 ? 125.527 120.952 113.389 1.00 53.85  ? 168 TYR A C    1 
ATOM   2387 O O    . TYR A 1 168 ? 126.709 120.691 113.638 1.00 53.85  ? 168 TYR A O    1 
ATOM   2388 C CB   . TYR A 1 168 ? 124.922 122.778 111.786 1.00 53.85  ? 168 TYR A CB   1 
ATOM   2389 C CG   . TYR A 1 168 ? 126.164 123.548 112.148 1.00 53.85  ? 168 TYR A CG   1 
ATOM   2390 C CD1  . TYR A 1 168 ? 127.368 123.288 111.514 1.00 53.85  ? 168 TYR A CD1  1 
ATOM   2391 C CD2  . TYR A 1 168 ? 126.139 124.528 113.125 1.00 53.85  ? 168 TYR A CD2  1 
ATOM   2392 C CE1  . TYR A 1 168 ? 128.512 123.983 111.842 1.00 53.85  ? 168 TYR A CE1  1 
ATOM   2393 C CE2  . TYR A 1 168 ? 127.279 125.230 113.460 1.00 53.85  ? 168 TYR A CE2  1 
ATOM   2394 C CZ   . TYR A 1 168 ? 128.463 124.953 112.815 1.00 53.85  ? 168 TYR A CZ   1 
ATOM   2395 O OH   . TYR A 1 168 ? 129.603 125.649 113.143 1.00 53.85  ? 168 TYR A OH   1 
ATOM   2396 H H    . TYR A 1 168 ? 123.178 121.082 111.501 1.00 53.85  ? 168 TYR A H    1 
ATOM   2397 H HA   . TYR A 1 168 ? 125.799 120.980 111.367 1.00 53.85  ? 168 TYR A HA   1 
ATOM   2398 H HB2  . TYR A 1 168 ? 124.712 122.964 110.857 1.00 53.85  ? 168 TYR A HB2  1 
ATOM   2399 H HB3  . TYR A 1 168 ? 124.201 123.085 112.358 1.00 53.85  ? 168 TYR A HB3  1 
ATOM   2400 H HD1  . TYR A 1 168 ? 127.405 122.631 110.857 1.00 53.85  ? 168 TYR A HD1  1 
ATOM   2401 H HD2  . TYR A 1 168 ? 125.340 124.717 113.563 1.00 53.85  ? 168 TYR A HD2  1 
ATOM   2402 H HE1  . TYR A 1 168 ? 129.313 123.797 111.407 1.00 53.85  ? 168 TYR A HE1  1 
ATOM   2403 H HE2  . TYR A 1 168 ? 127.247 125.887 114.118 1.00 53.85  ? 168 TYR A HE2  1 
ATOM   2404 H HH   . TYR A 1 168 ? 130.245 125.388 112.668 1.00 53.85  ? 168 TYR A HH   1 
ATOM   2405 N N    . ILE A 1 169 ? 124.590 120.962 114.339 1.00 52.26  ? 169 ILE A N    1 
ATOM   2406 C CA   . ILE A 1 169 ? 124.929 120.579 115.704 1.00 52.26  ? 169 ILE A CA   1 
ATOM   2407 C C    . ILE A 1 169 ? 125.364 119.127 115.762 1.00 52.26  ? 169 ILE A C    1 
ATOM   2408 O O    . ILE A 1 169 ? 126.089 118.735 116.681 1.00 52.26  ? 169 ILE A O    1 
ATOM   2409 C CB   . ILE A 1 169 ? 123.743 120.834 116.658 1.00 52.26  ? 169 ILE A CB   1 
ATOM   2410 C CG1  . ILE A 1 169 ? 124.130 120.478 118.095 1.00 52.26  ? 169 ILE A CG1  1 
ATOM   2411 C CG2  . ILE A 1 169 ? 122.532 120.025 116.236 1.00 52.26  ? 169 ILE A CG2  1 
ATOM   2412 C CD1  . ILE A 1 169 ? 123.082 120.856 119.127 1.00 52.26  ? 169 ILE A CD1  1 
ATOM   2413 H H    . ILE A 1 169 ? 123.769 121.186 114.219 1.00 52.26  ? 169 ILE A H    1 
ATOM   2414 H HA   . ILE A 1 169 ? 125.673 121.124 116.004 1.00 52.26  ? 169 ILE A HA   1 
ATOM   2415 H HB   . ILE A 1 169 ? 123.514 121.776 116.624 1.00 52.26  ? 169 ILE A HB   1 
ATOM   2416 H HG12 . ILE A 1 169 ? 124.264 119.520 118.157 1.00 52.26  ? 169 ILE A HG12 1 
ATOM   2417 H HG13 . ILE A 1 169 ? 124.952 120.941 118.323 1.00 52.26  ? 169 ILE A HG13 1 
ATOM   2418 H HG21 . ILE A 1 169 ? 121.784 120.253 116.809 1.00 52.26  ? 169 ILE A HG21 1 
ATOM   2419 H HG22 . ILE A 1 169 ? 122.317 120.239 115.317 1.00 52.26  ? 169 ILE A HG22 1 
ATOM   2420 H HG23 . ILE A 1 169 ? 122.735 119.080 116.318 1.00 52.26  ? 169 ILE A HG23 1 
ATOM   2421 H HD11 . ILE A 1 169 ? 123.448 120.713 120.014 1.00 52.26  ? 169 ILE A HD11 1 
ATOM   2422 H HD12 . ILE A 1 169 ? 122.850 121.791 119.013 1.00 52.26  ? 169 ILE A HD12 1 
ATOM   2423 H HD13 . ILE A 1 169 ? 122.297 120.302 119.001 1.00 52.26  ? 169 ILE A HD13 1 
ATOM   2424 N N    . ALA A 1 170 ? 124.935 118.311 114.800 1.00 51.30  ? 170 ALA A N    1 
ATOM   2425 C CA   . ALA A 1 170 ? 125.312 116.903 114.794 1.00 51.30  ? 170 ALA A CA   1 
ATOM   2426 C C    . ALA A 1 170 ? 126.752 116.716 114.334 1.00 51.30  ? 170 ALA A C    1 
ATOM   2427 O O    . ALA A 1 170 ? 127.572 116.134 115.051 1.00 51.30  ? 170 ALA A O    1 
ATOM   2428 C CB   . ALA A 1 170 ? 124.359 116.109 113.898 1.00 51.30  ? 170 ALA A CB   1 
ATOM   2429 H H    . ALA A 1 170 ? 124.427 118.546 114.147 1.00 51.30  ? 170 ALA A H    1 
ATOM   2430 H HA   . ALA A 1 170 ? 125.239 116.554 115.694 1.00 51.30  ? 170 ALA A HA   1 
ATOM   2431 H HB1  . ALA A 1 170 ? 124.584 115.168 113.951 1.00 51.30  ? 170 ALA A HB1  1 
ATOM   2432 H HB2  . ALA A 1 170 ? 123.449 116.251 114.203 1.00 51.30  ? 170 ALA A HB2  1 
ATOM   2433 H HB3  . ALA A 1 170 ? 124.451 116.422 112.984 1.00 51.30  ? 170 ALA A HB3  1 
ATOM   2434 N N    . ASP A 1 171 ? 127.079 117.204 113.138 1.00 54.57  ? 171 ASP A N    1 
ATOM   2435 C CA   . ASP A 1 171 ? 128.382 116.888 112.561 1.00 54.57  ? 171 ASP A CA   1 
ATOM   2436 C C    . ASP A 1 171 ? 129.523 117.668 113.197 1.00 54.57  ? 171 ASP A C    1 
ATOM   2437 O O    . ASP A 1 171 ? 130.623 117.126 113.337 1.00 54.57  ? 171 ASP A O    1 
ATOM   2438 C CB   . ASP A 1 171 ? 128.372 117.134 111.055 1.00 54.57  ? 171 ASP A CB   1 
ATOM   2439 C CG   . ASP A 1 171 ? 128.065 115.879 110.266 1.00 54.57  ? 171 ASP A CG   1 
ATOM   2440 O OD1  . ASP A 1 171 ? 127.759 114.842 110.889 1.00 54.57  ? 171 ASP A OD1  1 
ATOM   2441 O OD2  . ASP A 1 171 ? 128.134 115.924 109.021 1.00 54.57  ? 171 ASP A OD2  1 
ATOM   2442 H H    . ASP A 1 171 ? 126.577 117.704 112.652 1.00 54.57  ? 171 ASP A H    1 
ATOM   2443 H HA   . ASP A 1 171 ? 128.566 115.948 112.713 1.00 54.57  ? 171 ASP A HA   1 
ATOM   2444 H HB2  . ASP A 1 171 ? 127.695 117.796 110.846 1.00 54.57  ? 171 ASP A HB2  1 
ATOM   2445 H HB3  . ASP A 1 171 ? 129.246 117.457 110.782 1.00 54.57  ? 171 ASP A HB3  1 
ATOM   2446 N N    . ARG A 1 172 ? 129.305 118.925 113.585 1.00 58.77  ? 172 ARG A N    1 
ATOM   2447 C CA   . ARG A 1 172 ? 130.413 119.708 114.124 1.00 58.77  ? 172 ARG A CA   1 
ATOM   2448 C C    . ARG A 1 172 ? 130.877 119.170 115.473 1.00 58.77  ? 172 ARG A C    1 
ATOM   2449 O O    . ARG A 1 172 ? 132.073 119.210 115.781 1.00 58.77  ? 172 ARG A O    1 
ATOM   2450 C CB   . ARG A 1 172 ? 130.026 121.180 114.252 1.00 58.77  ? 172 ARG A CB   1 
ATOM   2451 C CG   . ARG A 1 172 ? 131.061 121.995 115.022 1.00 58.77  ? 172 ARG A CG   1 
ATOM   2452 C CD   . ARG A 1 172 ? 130.811 123.490 114.958 1.00 58.77  ? 172 ARG A CD   1 
ATOM   2453 N NE   . ARG A 1 172 ? 131.698 124.208 115.867 1.00 58.77  ? 172 ARG A NE   1 
ATOM   2454 C CZ   . ARG A 1 172 ? 131.688 125.521 116.051 1.00 58.77  ? 172 ARG A CZ   1 
ATOM   2455 N NH1  . ARG A 1 172 ? 130.851 126.306 115.393 1.00 58.77  ? 172 ARG A NH1  1 
ATOM   2456 N NH2  . ARG A 1 172 ? 132.538 126.060 116.920 1.00 58.77  ? 172 ARG A NH2  1 
ATOM   2457 H H    . ARG A 1 172 ? 128.551 119.336 113.547 1.00 58.77  ? 172 ARG A H    1 
ATOM   2458 H HA   . ARG A 1 172 ? 131.162 119.651 113.510 1.00 58.77  ? 172 ARG A HA   1 
ATOM   2459 H HB2  . ARG A 1 172 ? 129.942 121.563 113.365 1.00 58.77  ? 172 ARG A HB2  1 
ATOM   2460 H HB3  . ARG A 1 172 ? 129.181 121.245 114.724 1.00 58.77  ? 172 ARG A HB3  1 
ATOM   2461 H HG2  . ARG A 1 172 ? 131.039 121.738 115.957 1.00 58.77  ? 172 ARG A HG2  1 
ATOM   2462 H HG3  . ARG A 1 172 ? 131.940 121.821 114.651 1.00 58.77  ? 172 ARG A HG3  1 
ATOM   2463 H HD2  . ARG A 1 172 ? 130.980 123.805 114.056 1.00 58.77  ? 172 ARG A HD2  1 
ATOM   2464 H HD3  . ARG A 1 172 ? 129.894 123.676 115.214 1.00 58.77  ? 172 ARG A HD3  1 
ATOM   2465 H HE   . ARG A 1 172 ? 132.221 123.740 116.365 1.00 58.77  ? 172 ARG A HE   1 
ATOM   2466 H HH11 . ARG A 1 172 ? 130.296 125.970 114.828 1.00 58.77  ? 172 ARG A HH11 1 
ATOM   2467 H HH12 . ARG A 1 172 ? 130.864 127.155 115.529 1.00 58.77  ? 172 ARG A HH12 1 
ATOM   2468 H HH21 . ARG A 1 172 ? 133.086 125.558 117.354 1.00 58.77  ? 172 ARG A HH21 1 
ATOM   2469 H HH22 . ARG A 1 172 ? 132.542 126.910 117.049 1.00 58.77  ? 172 ARG A HH22 1 
ATOM   2470 N N    . PHE A 1 173 ? 129.952 118.677 116.299 1.00 55.57  ? 173 PHE A N    1 
ATOM   2471 C CA   . PHE A 1 173 ? 130.266 118.283 117.667 1.00 55.57  ? 173 PHE A CA   1 
ATOM   2472 C C    . PHE A 1 173 ? 130.245 116.770 117.873 1.00 55.57  ? 173 PHE A C    1 
ATOM   2473 O O    . PHE A 1 173 ? 130.155 116.309 119.014 1.00 55.57  ? 173 PHE A O    1 
ATOM   2474 C CB   . PHE A 1 173 ? 129.302 118.962 118.639 1.00 55.57  ? 173 PHE A CB   1 
ATOM   2475 C CG   . PHE A 1 173 ? 129.336 120.458 118.568 1.00 55.57  ? 173 PHE A CG   1 
ATOM   2476 C CD1  . PHE A 1 173 ? 130.393 121.164 119.112 1.00 55.57  ? 173 PHE A CD1  1 
ATOM   2477 C CD2  . PHE A 1 173 ? 128.313 121.158 117.956 1.00 55.57  ? 173 PHE A CD2  1 
ATOM   2478 C CE1  . PHE A 1 173 ? 130.429 122.542 119.047 1.00 55.57  ? 173 PHE A CE1  1 
ATOM   2479 C CE2  . PHE A 1 173 ? 128.343 122.536 117.888 1.00 55.57  ? 173 PHE A CE2  1 
ATOM   2480 C CZ   . PHE A 1 173 ? 129.403 123.228 118.434 1.00 55.57  ? 173 PHE A CZ   1 
ATOM   2481 H H    . PHE A 1 173 ? 129.127 118.562 116.086 1.00 55.57  ? 173 PHE A H    1 
ATOM   2482 H HA   . PHE A 1 173 ? 131.159 118.592 117.884 1.00 55.57  ? 173 PHE A HA   1 
ATOM   2483 H HB2  . PHE A 1 173 ? 128.398 118.675 118.436 1.00 55.57  ? 173 PHE A HB2  1 
ATOM   2484 H HB3  . PHE A 1 173 ? 129.535 118.702 119.544 1.00 55.57  ? 173 PHE A HB3  1 
ATOM   2485 H HD1  . PHE A 1 173 ? 131.088 120.706 119.526 1.00 55.57  ? 173 PHE A HD1  1 
ATOM   2486 H HD2  . PHE A 1 173 ? 127.597 120.695 117.586 1.00 55.57  ? 173 PHE A HD2  1 
ATOM   2487 H HE1  . PHE A 1 173 ? 131.145 123.007 119.416 1.00 55.57  ? 173 PHE A HE1  1 
ATOM   2488 H HE2  . PHE A 1 173 ? 127.650 122.997 117.474 1.00 55.57  ? 173 PHE A HE2  1 
ATOM   2489 H HZ   . PHE A 1 173 ? 129.425 124.157 118.389 1.00 55.57  ? 173 PHE A HZ   1 
ATOM   2490 N N    . GLY A 1 174 ? 130.323 115.993 116.806 1.00 54.74  ? 174 GLY A N    1 
ATOM   2491 C CA   . GLY A 1 174 ? 130.404 114.552 116.941 1.00 54.74  ? 174 GLY A CA   1 
ATOM   2492 C C    . GLY A 1 174 ? 129.052 113.882 116.790 1.00 54.74  ? 174 GLY A C    1 
ATOM   2493 O O    . GLY A 1 174 ? 127.997 114.477 117.035 1.00 54.74  ? 174 GLY A O    1 
ATOM   2494 H H    . GLY A 1 174 ? 130.334 116.275 115.993 1.00 54.74  ? 174 GLY A H    1 
ATOM   2495 H HA2  . GLY A 1 174 ? 130.994 114.198 116.260 1.00 54.74  ? 174 GLY A HA2  1 
ATOM   2496 H HA3  . GLY A 1 174 ? 130.767 114.324 117.811 1.00 54.74  ? 174 GLY A HA3  1 
ATOM   2497 N N    . ARG A 1 175 ? 129.080 112.613 116.380 1.00 54.11  ? 175 ARG A N    1 
ATOM   2498 C CA   . ARG A 1 175 ? 127.855 111.864 116.130 1.00 54.11  ? 175 ARG A CA   1 
ATOM   2499 C C    . ARG A 1 175 ? 127.273 111.219 117.378 1.00 54.11  ? 175 ARG A C    1 
ATOM   2500 O O    . ARG A 1 175 ? 126.123 110.772 117.334 1.00 54.11  ? 175 ARG A O    1 
ATOM   2501 C CB   . ARG A 1 175 ? 128.108 110.781 115.085 1.00 54.11  ? 175 ARG A CB   1 
ATOM   2502 C CG   . ARG A 1 175 ? 128.207 111.315 113.678 1.00 54.11  ? 175 ARG A CG   1 
ATOM   2503 C CD   . ARG A 1 175 ? 128.730 110.266 112.724 1.00 54.11  ? 175 ARG A CD   1 
ATOM   2504 N NE   . ARG A 1 175 ? 128.706 110.738 111.347 1.00 54.11  ? 175 ARG A NE   1 
ATOM   2505 C CZ   . ARG A 1 175 ? 129.542 111.638 110.853 1.00 54.11  ? 175 ARG A CZ   1 
ATOM   2506 N NH1  . ARG A 1 175 ? 130.474 112.201 111.603 1.00 54.11  ? 175 ARG A NH1  1 
ATOM   2507 N NH2  . ARG A 1 175 ? 129.438 111.987 109.576 1.00 54.11  ? 175 ARG A NH2  1 
ATOM   2508 H H    . ARG A 1 175 ? 129.800 112.164 116.239 1.00 54.11  ? 175 ARG A H    1 
ATOM   2509 H HA   . ARG A 1 175 ? 127.188 112.470 115.772 1.00 54.11  ? 175 ARG A HA   1 
ATOM   2510 H HB2  . ARG A 1 175 ? 128.943 110.333 115.293 1.00 54.11  ? 175 ARG A HB2  1 
ATOM   2511 H HB3  . ARG A 1 175 ? 127.377 110.145 115.111 1.00 54.11  ? 175 ARG A HB3  1 
ATOM   2512 H HG2  . ARG A 1 175 ? 127.326 111.586 113.377 1.00 54.11  ? 175 ARG A HG2  1 
ATOM   2513 H HG3  . ARG A 1 175 ? 128.814 112.070 113.665 1.00 54.11  ? 175 ARG A HG3  1 
ATOM   2514 H HD2  . ARG A 1 175 ? 129.648 110.052 112.956 1.00 54.11  ? 175 ARG A HD2  1 
ATOM   2515 H HD3  . ARG A 1 175 ? 128.177 109.471 112.785 1.00 54.11  ? 175 ARG A HD3  1 
ATOM   2516 H HE   . ARG A 1 175 ? 128.179 110.338 110.797 1.00 54.11  ? 175 ARG A HE   1 
ATOM   2517 H HH11 . ARG A 1 175 ? 131.006 112.784 111.261 1.00 54.11  ? 175 ARG A HH11 1 
ATOM   2518 H HH12 . ARG A 1 175 ? 130.554 111.985 112.431 1.00 54.11  ? 175 ARG A HH12 1 
ATOM   2519 H HH21 . ARG A 1 175 ? 129.975 112.572 109.245 1.00 54.11  ? 175 ARG A HH21 1 
ATOM   2520 H HH22 . ARG A 1 175 ? 128.835 111.628 109.079 1.00 54.11  ? 175 ARG A HH22 1 
ATOM   2521 N N    . LYS A 1 176 ? 128.020 111.154 118.479 1.00 55.40  ? 176 LYS A N    1 
ATOM   2522 C CA   . LYS A 1 176 ? 127.484 110.603 119.716 1.00 55.40  ? 176 LYS A CA   1 
ATOM   2523 C C    . LYS A 1 176 ? 127.056 111.678 120.701 1.00 55.40  ? 176 LYS A C    1 
ATOM   2524 O O    . LYS A 1 176 ? 126.217 111.403 121.565 1.00 55.40  ? 176 LYS A O    1 
ATOM   2525 C CB   . LYS A 1 176 ? 128.512 109.690 120.393 1.00 55.40  ? 176 LYS A CB   1 
ATOM   2526 C CG   . LYS A 1 176 ? 127.919 108.809 121.481 1.00 55.40  ? 176 LYS A CG   1 
ATOM   2527 C CD   . LYS A 1 176 ? 128.991 108.017 122.204 1.00 55.40  ? 176 LYS A CD   1 
ATOM   2528 C CE   . LYS A 1 176 ? 128.392 107.103 123.258 1.00 55.40  ? 176 LYS A CE   1 
ATOM   2529 N NZ   . LYS A 1 176 ? 129.439 106.393 124.043 1.00 55.40  ? 176 LYS A NZ   1 
ATOM   2530 H H    . LYS A 1 176 ? 128.836 111.420 118.534 1.00 55.40  ? 176 LYS A H    1 
ATOM   2531 H HA   . LYS A 1 176 ? 126.704 110.065 119.512 1.00 55.40  ? 176 LYS A HA   1 
ATOM   2532 H HB2  . LYS A 1 176 ? 128.905 109.110 119.722 1.00 55.40  ? 176 LYS A HB2  1 
ATOM   2533 H HB3  . LYS A 1 176 ? 129.200 110.240 120.799 1.00 55.40  ? 176 LYS A HB3  1 
ATOM   2534 H HG2  . LYS A 1 176 ? 127.462 109.363 122.132 1.00 55.40  ? 176 LYS A HG2  1 
ATOM   2535 H HG3  . LYS A 1 176 ? 127.297 108.181 121.080 1.00 55.40  ? 176 LYS A HG3  1 
ATOM   2536 H HD2  . LYS A 1 176 ? 129.473 107.469 121.565 1.00 55.40  ? 176 LYS A HD2  1 
ATOM   2537 H HD3  . LYS A 1 176 ? 129.599 108.630 122.646 1.00 55.40  ? 176 LYS A HD3  1 
ATOM   2538 H HE2  . LYS A 1 176 ? 127.860 107.632 123.873 1.00 55.40  ? 176 LYS A HE2  1 
ATOM   2539 H HE3  . LYS A 1 176 ? 127.836 106.437 122.824 1.00 55.40  ? 176 LYS A HE3  1 
ATOM   2540 H HZ1  . LYS A 1 176 ? 129.059 105.887 124.669 1.00 55.40  ? 176 LYS A HZ1  1 
ATOM   2541 H HZ2  . LYS A 1 176 ? 129.923 105.875 123.506 1.00 55.40  ? 176 LYS A HZ2  1 
ATOM   2542 H HZ3  . LYS A 1 176 ? 129.976 106.984 124.437 1.00 55.40  ? 176 LYS A HZ3  1 
ATOM   2543 N N    . LEU A 1 177 ? 127.609 112.887 120.597 1.00 51.70  ? 177 LEU A N    1 
ATOM   2544 C CA   . LEU A 1 177 ? 127.101 113.994 121.395 1.00 51.70  ? 177 LEU A CA   1 
ATOM   2545 C C    . LEU A 1 177 ? 125.707 114.398 120.939 1.00 51.70  ? 177 LEU A C    1 
ATOM   2546 O O    . LEU A 1 177 ? 124.902 114.867 121.749 1.00 51.70  ? 177 LEU A O    1 
ATOM   2547 C CB   . LEU A 1 177 ? 128.061 115.180 121.310 1.00 51.70  ? 177 LEU A CB   1 
ATOM   2548 C CG   . LEU A 1 177 ? 128.024 116.184 122.463 1.00 51.70  ? 177 LEU A CG   1 
ATOM   2549 C CD1  . LEU A 1 177 ? 129.228 117.107 122.385 1.00 51.70  ? 177 LEU A CD1  1 
ATOM   2550 C CD2  . LEU A 1 177 ? 126.737 116.988 122.460 1.00 51.70  ? 177 LEU A CD2  1 
ATOM   2551 H H    . LEU A 1 177 ? 128.268 113.087 120.081 1.00 51.70  ? 177 LEU A H    1 
ATOM   2552 H HA   . LEU A 1 177 ? 127.046 113.718 122.324 1.00 51.70  ? 177 LEU A HA   1 
ATOM   2553 H HB2  . LEU A 1 177 ? 128.965 114.832 121.264 1.00 51.70  ? 177 LEU A HB2  1 
ATOM   2554 H HB3  . LEU A 1 177 ? 127.866 115.670 120.496 1.00 51.70  ? 177 LEU A HB3  1 
ATOM   2555 H HG   . LEU A 1 177 ? 128.073 115.701 123.303 1.00 51.70  ? 177 LEU A HG   1 
ATOM   2556 H HD11 . LEU A 1 177 ? 129.205 117.722 123.135 1.00 51.70  ? 177 LEU A HD11 1 
ATOM   2557 H HD12 . LEU A 1 177 ? 130.037 116.573 122.420 1.00 51.70  ? 177 LEU A HD12 1 
ATOM   2558 H HD13 . LEU A 1 177 ? 129.193 117.601 121.551 1.00 51.70  ? 177 LEU A HD13 1 
ATOM   2559 H HD21 . LEU A 1 177 ? 126.919 117.876 122.805 1.00 51.70  ? 177 LEU A HD21 1 
ATOM   2560 H HD22 . LEU A 1 177 ? 126.403 117.048 121.551 1.00 51.70  ? 177 LEU A HD22 1 
ATOM   2561 H HD23 . LEU A 1 177 ? 126.085 116.542 123.023 1.00 51.70  ? 177 LEU A HD23 1 
ATOM   2562 N N    . CYS A 1 178 ? 125.406 114.221 119.652 1.00 47.29  ? 178 CYS A N    1 
ATOM   2563 C CA   . CYS A 1 178 ? 124.075 114.515 119.135 1.00 47.29  ? 178 CYS A CA   1 
ATOM   2564 C C    . CYS A 1 178 ? 123.090 113.399 119.462 1.00 47.29  ? 178 CYS A C    1 
ATOM   2565 O O    . CYS A 1 178 ? 122.044 113.640 120.073 1.00 47.29  ? 178 CYS A O    1 
ATOM   2566 C CB   . CYS A 1 178 ? 124.135 114.737 117.625 1.00 47.29  ? 178 CYS A CB   1 
ATOM   2567 S SG   . CYS A 1 178 ? 122.547 114.517 116.796 1.00 47.29  ? 178 CYS A SG   1 
ATOM   2568 H H    . CYS A 1 178 ? 125.958 113.933 119.058 1.00 47.29  ? 178 CYS A H    1 
ATOM   2569 H HA   . CYS A 1 178 ? 123.749 115.331 119.546 1.00 47.29  ? 178 CYS A HA   1 
ATOM   2570 H HB2  . CYS A 1 178 ? 124.429 115.645 117.464 1.00 47.29  ? 178 CYS A HB2  1 
ATOM   2571 H HB3  . CYS A 1 178 ? 124.766 114.110 117.237 1.00 47.29  ? 178 CYS A HB3  1 
ATOM   2572 H HG   . CYS A 1 178 ? 122.699 114.671 115.616 1.00 47.29  ? 178 CYS A HG   1 
ATOM   2573 N N    . LEU A 1 179 ? 123.407 112.168 119.057 1.00 46.95  ? 179 LEU A N    1 
ATOM   2574 C CA   . LEU A 1 179 ? 122.474 111.065 119.259 1.00 46.95  ? 179 LEU A CA   1 
ATOM   2575 C C    . LEU A 1 179 ? 122.042 110.967 120.716 1.00 46.95  ? 179 LEU A C    1 
ATOM   2576 O O    . LEU A 1 179 ? 120.884 110.655 121.009 1.00 46.95  ? 179 LEU A O    1 
ATOM   2577 C CB   . LEU A 1 179 ? 123.109 109.753 118.798 1.00 46.95  ? 179 LEU A CB   1 
ATOM   2578 C CG   . LEU A 1 179 ? 122.261 108.492 118.968 1.00 46.95  ? 179 LEU A CG   1 
ATOM   2579 C CD1  . LEU A 1 179 ? 122.486 107.550 117.801 1.00 46.95  ? 179 LEU A CD1  1 
ATOM   2580 C CD2  . LEU A 1 179 ? 122.583 107.787 120.276 1.00 46.95  ? 179 LEU A CD2  1 
ATOM   2581 H H    . LEU A 1 179 ? 124.143 111.949 118.670 1.00 46.95  ? 179 LEU A H    1 
ATOM   2582 H HA   . LEU A 1 179 ? 121.681 111.219 118.722 1.00 46.95  ? 179 LEU A HA   1 
ATOM   2583 H HB2  . LEU A 1 179 ? 123.321 109.833 117.855 1.00 46.95  ? 179 LEU A HB2  1 
ATOM   2584 H HB3  . LEU A 1 179 ? 123.928 109.618 119.299 1.00 46.95  ? 179 LEU A HB3  1 
ATOM   2585 H HG   . LEU A 1 179 ? 121.323 108.738 118.980 1.00 46.95  ? 179 LEU A HG   1 
ATOM   2586 H HD11 . LEU A 1 179 ? 121.953 106.750 117.934 1.00 46.95  ? 179 LEU A HD11 1 
ATOM   2587 H HD12 . LEU A 1 179 ? 122.218 107.992 116.981 1.00 46.95  ? 179 LEU A HD12 1 
ATOM   2588 H HD13 . LEU A 1 179 ? 123.426 107.316 117.761 1.00 46.95  ? 179 LEU A HD13 1 
ATOM   2589 H HD21 . LEU A 1 179 ? 122.054 106.976 120.333 1.00 46.95  ? 179 LEU A HD21 1 
ATOM   2590 H HD22 . LEU A 1 179 ? 123.527 107.566 120.291 1.00 46.95  ? 179 LEU A HD22 1 
ATOM   2591 H HD23 . LEU A 1 179 ? 122.368 108.372 121.018 1.00 46.95  ? 179 LEU A HD23 1 
ATOM   2592 N N    . LEU A 1 180 ? 122.963 111.222 121.645 1.00 49.72  ? 180 LEU A N    1 
ATOM   2593 C CA   . LEU A 1 180 ? 122.614 111.199 123.061 1.00 49.72  ? 180 LEU A CA   1 
ATOM   2594 C C    . LEU A 1 180 ? 121.661 112.337 123.409 1.00 49.72  ? 180 LEU A C    1 
ATOM   2595 O O    . LEU A 1 180 ? 120.583 112.117 123.975 1.00 49.72  ? 180 LEU A O    1 
ATOM   2596 C CB   . LEU A 1 180 ? 123.887 111.288 123.902 1.00 49.72  ? 180 LEU A CB   1 
ATOM   2597 C CG   . LEU A 1 180 ? 123.723 111.042 125.398 1.00 49.72  ? 180 LEU A CG   1 
ATOM   2598 C CD1  . LEU A 1 180 ? 123.450 109.573 125.656 1.00 49.72  ? 180 LEU A CD1  1 
ATOM   2599 C CD2  . LEU A 1 180 ? 124.956 111.507 126.156 1.00 49.72  ? 180 LEU A CD2  1 
ATOM   2600 H H    . LEU A 1 180 ? 123.787 111.407 121.483 1.00 49.72  ? 180 LEU A H    1 
ATOM   2601 H HA   . LEU A 1 180 ? 122.172 110.361 123.267 1.00 49.72  ? 180 LEU A HA   1 
ATOM   2602 H HB2  . LEU A 1 180 ? 124.521 110.634 123.568 1.00 49.72  ? 180 LEU A HB2  1 
ATOM   2603 H HB3  . LEU A 1 180 ? 124.258 112.178 123.797 1.00 49.72  ? 180 LEU A HB3  1 
ATOM   2604 H HG   . LEU A 1 180 ? 122.962 111.550 125.722 1.00 49.72  ? 180 LEU A HG   1 
ATOM   2605 H HD11 . LEU A 1 180 ? 123.428 109.422 126.613 1.00 49.72  ? 180 LEU A HD11 1 
ATOM   2606 H HD12 . LEU A 1 180 ? 122.595 109.336 125.263 1.00 49.72  ? 180 LEU A HD12 1 
ATOM   2607 H HD13 . LEU A 1 180 ? 124.158 109.046 125.254 1.00 49.72  ? 180 LEU A HD13 1 
ATOM   2608 H HD21 . LEU A 1 180 ? 124.834 111.321 127.100 1.00 49.72  ? 180 LEU A HD21 1 
ATOM   2609 H HD22 . LEU A 1 180 ? 125.732 111.031 125.821 1.00 49.72  ? 180 LEU A HD22 1 
ATOM   2610 H HD23 . LEU A 1 180 ? 125.068 112.461 126.019 1.00 49.72  ? 180 LEU A HD23 1 
ATOM   2611 N N    . ALA A 1 181 ? 122.042 113.569 123.063 1.00 47.74  ? 181 ALA A N    1 
ATOM   2612 C CA   . ALA A 1 181 ? 121.225 114.722 123.425 1.00 47.74  ? 181 ALA A CA   1 
ATOM   2613 C C    . ALA A 1 181 ? 119.872 114.684 122.728 1.00 47.74  ? 181 ALA A C    1 
ATOM   2614 O O    . ALA A 1 181 ? 118.843 114.993 123.339 1.00 47.74  ? 181 ALA A O    1 
ATOM   2615 C CB   . ALA A 1 181 ? 121.963 116.016 123.085 1.00 47.74  ? 181 ALA A CB   1 
ATOM   2616 H H    . ALA A 1 181 ? 122.758 113.759 122.627 1.00 47.74  ? 181 ALA A H    1 
ATOM   2617 H HA   . ALA A 1 181 ? 121.069 114.709 124.382 1.00 47.74  ? 181 ALA A HA   1 
ATOM   2618 H HB1  . ALA A 1 181 ? 121.403 116.771 123.324 1.00 47.74  ? 181 ALA A HB1  1 
ATOM   2619 H HB2  . ALA A 1 181 ? 122.793 116.047 123.586 1.00 47.74  ? 181 ALA A HB2  1 
ATOM   2620 H HB3  . ALA A 1 181 ? 122.150 116.032 122.133 1.00 47.74  ? 181 ALA A HB3  1 
ATOM   2621 N N    . THR A 1 182 ? 119.852 114.316 121.447 1.00 45.35  ? 182 THR A N    1 
ATOM   2622 C CA   . THR A 1 182 ? 118.597 114.316 120.705 1.00 45.35  ? 182 THR A CA   1 
ATOM   2623 C C    . THR A 1 182 ? 117.615 113.310 121.290 1.00 45.35  ? 182 THR A C    1 
ATOM   2624 O O    . THR A 1 182 ? 116.443 113.629 121.516 1.00 45.35  ? 182 THR A O    1 
ATOM   2625 C CB   . THR A 1 182 ? 118.854 114.017 119.231 1.00 45.35  ? 182 THR A CB   1 
ATOM   2626 O OG1  . THR A 1 182 ? 119.584 112.792 119.112 1.00 45.35  ? 182 THR A OG1  1 
ATOM   2627 C CG2  . THR A 1 182 ? 119.642 115.146 118.590 1.00 45.35  ? 182 THR A CG2  1 
ATOM   2628 H H    . THR A 1 182 ? 120.539 114.067 120.993 1.00 45.35  ? 182 THR A H    1 
ATOM   2629 H HA   . THR A 1 182 ? 118.201 115.198 120.770 1.00 45.35  ? 182 THR A HA   1 
ATOM   2630 H HB   . THR A 1 182 ? 118.008 113.932 118.766 1.00 45.35  ? 182 THR A HB   1 
ATOM   2631 H HG1  . THR A 1 182 ? 119.769 112.644 118.306 1.00 45.35  ? 182 THR A HG1  1 
ATOM   2632 H HG21 . THR A 1 182 ? 119.832 114.932 117.663 1.00 45.35  ? 182 THR A HG21 1 
ATOM   2633 H HG22 . THR A 1 182 ? 119.131 115.970 118.625 1.00 45.35  ? 182 THR A HG22 1 
ATOM   2634 H HG23 . THR A 1 182 ? 120.480 115.276 119.062 1.00 45.35  ? 182 THR A HG23 1 
ATOM   2635 N N    . THR A 1 183 ? 118.071 112.081 121.539 1.00 45.46  ? 183 THR A N    1 
ATOM   2636 C CA   . THR A 1 183 ? 117.165 111.088 122.102 1.00 45.46  ? 183 THR A CA   1 
ATOM   2637 C C    . THR A 1 183 ? 116.753 111.456 123.521 1.00 45.46  ? 183 THR A C    1 
ATOM   2638 O O    . THR A 1 183 ? 115.607 111.208 123.912 1.00 45.46  ? 183 THR A O    1 
ATOM   2639 C CB   . THR A 1 183 ? 117.799 109.697 122.073 1.00 45.46  ? 183 THR A CB   1 
ATOM   2640 O OG1  . THR A 1 183 ? 116.808 108.714 122.391 1.00 45.46  ? 183 THR A OG1  1 
ATOM   2641 C CG2  . THR A 1 183 ? 118.932 109.593 123.072 1.00 45.46  ? 183 THR A CG2  1 
ATOM   2642 H H    . THR A 1 183 ? 118.873 111.807 121.395 1.00 45.46  ? 183 THR A H    1 
ATOM   2643 H HA   . THR A 1 183 ? 116.361 111.058 121.560 1.00 45.46  ? 183 THR A HA   1 
ATOM   2644 H HB   . THR A 1 183 ? 118.154 109.523 121.187 1.00 45.46  ? 183 THR A HB   1 
ATOM   2645 H HG1  . THR A 1 183 ? 117.146 107.946 122.363 1.00 45.46  ? 183 THR A HG1  1 
ATOM   2646 H HG21 . THR A 1 183 ? 119.441 108.783 122.911 1.00 45.46  ? 183 THR A HG21 1 
ATOM   2647 H HG22 . THR A 1 183 ? 119.521 110.355 122.979 1.00 45.46  ? 183 THR A HG22 1 
ATOM   2648 H HG23 . THR A 1 183 ? 118.582 109.569 123.976 1.00 45.46  ? 183 THR A HG23 1 
ATOM   2649 N N    . LEU A 1 184 ? 117.653 112.059 124.302 1.00 44.11  ? 184 LEU A N    1 
ATOM   2650 C CA   . LEU A 1 184 ? 117.268 112.485 125.644 1.00 44.11  ? 184 LEU A CA   1 
ATOM   2651 C C    . LEU A 1 184 ? 116.175 113.545 125.593 1.00 44.11  ? 184 LEU A C    1 
ATOM   2652 O O    . LEU A 1 184 ? 115.200 113.480 126.353 1.00 44.11  ? 184 LEU A O    1 
ATOM   2653 C CB   . LEU A 1 184 ? 118.487 113.012 126.397 1.00 44.11  ? 184 LEU A CB   1 
ATOM   2654 C CG   . LEU A 1 184 ? 118.236 113.408 127.851 1.00 44.11  ? 184 LEU A CG   1 
ATOM   2655 C CD1  . LEU A 1 184 ? 117.741 112.217 128.653 1.00 44.11  ? 184 LEU A CD1  1 
ATOM   2656 C CD2  . LEU A 1 184 ? 119.498 113.984 128.470 1.00 44.11  ? 184 LEU A CD2  1 
ATOM   2657 H H    . LEU A 1 184 ? 118.468 112.228 124.085 1.00 44.11  ? 184 LEU A H    1 
ATOM   2658 H HA   . LEU A 1 184 ? 116.921 111.719 126.126 1.00 44.11  ? 184 LEU A HA   1 
ATOM   2659 H HB2  . LEU A 1 184 ? 119.170 112.323 126.397 1.00 44.11  ? 184 LEU A HB2  1 
ATOM   2660 H HB3  . LEU A 1 184 ? 118.818 113.797 125.934 1.00 44.11  ? 184 LEU A HB3  1 
ATOM   2661 H HG   . LEU A 1 184 ? 117.551 114.094 127.880 1.00 44.11  ? 184 LEU A HG   1 
ATOM   2662 H HD11 . LEU A 1 184 ? 117.733 112.453 129.594 1.00 44.11  ? 184 LEU A HD11 1 
ATOM   2663 H HD12 . LEU A 1 184 ? 116.843 111.990 128.363 1.00 44.11  ? 184 LEU A HD12 1 
ATOM   2664 H HD13 . LEU A 1 184 ? 118.338 111.467 128.505 1.00 44.11  ? 184 LEU A HD13 1 
ATOM   2665 H HD21 . LEU A 1 184 ? 119.311 114.240 129.387 1.00 44.11  ? 184 LEU A HD21 1 
ATOM   2666 H HD22 . LEU A 1 184 ? 120.195 113.311 128.450 1.00 44.11  ? 184 LEU A HD22 1 
ATOM   2667 H HD23 . LEU A 1 184 ? 119.773 114.762 127.960 1.00 44.11  ? 184 LEU A HD23 1 
ATOM   2668 N N    . ILE A 1 185 ? 116.319 114.532 124.705 1.00 43.18  ? 185 ILE A N    1 
ATOM   2669 C CA   . ILE A 1 185 ? 115.303 115.575 124.581 1.00 43.18  ? 185 ILE A CA   1 
ATOM   2670 C C    . ILE A 1 185 ? 113.988 114.982 124.097 1.00 43.18  ? 185 ILE A C    1 
ATOM   2671 O O    . ILE A 1 185 ? 112.910 115.340 124.586 1.00 43.18  ? 185 ILE A O    1 
ATOM   2672 C CB   . ILE A 1 185 ? 115.791 116.699 123.650 1.00 43.18  ? 185 ILE A CB   1 
ATOM   2673 C CG1  . ILE A 1 185 ? 116.754 117.618 124.403 1.00 43.18  ? 185 ILE A CG1  1 
ATOM   2674 C CG2  . ILE A 1 185 ? 114.607 117.484 123.099 1.00 43.18  ? 185 ILE A CG2  1 
ATOM   2675 C CD1  . ILE A 1 185 ? 117.380 118.699 123.549 1.00 43.18  ? 185 ILE A CD1  1 
ATOM   2676 H H    . ILE A 1 185 ? 116.988 114.619 124.171 1.00 43.18  ? 185 ILE A H    1 
ATOM   2677 H HA   . ILE A 1 185 ? 115.151 115.966 125.455 1.00 43.18  ? 185 ILE A HA   1 
ATOM   2678 H HB   . ILE A 1 185 ? 116.267 116.298 122.906 1.00 43.18  ? 185 ILE A HB   1 
ATOM   2679 H HG12 . ILE A 1 185 ? 116.270 118.054 125.122 1.00 43.18  ? 185 ILE A HG12 1 
ATOM   2680 H HG13 . ILE A 1 185 ? 117.473 117.081 124.772 1.00 43.18  ? 185 ILE A HG13 1 
ATOM   2681 H HG21 . ILE A 1 185 ? 114.922 118.312 122.708 1.00 43.18  ? 185 ILE A HG21 1 
ATOM   2682 H HG22 . ILE A 1 185 ? 114.163 116.957 122.417 1.00 43.18  ? 185 ILE A HG22 1 
ATOM   2683 H HG23 . ILE A 1 185 ? 113.992 117.679 123.824 1.00 43.18  ? 185 ILE A HG23 1 
ATOM   2684 H HD11 . ILE A 1 185 ? 118.141 119.072 124.022 1.00 43.18  ? 185 ILE A HD11 1 
ATOM   2685 H HD12 . ILE A 1 185 ? 117.671 118.309 122.710 1.00 43.18  ? 185 ILE A HD12 1 
ATOM   2686 H HD13 . ILE A 1 185 ? 116.724 119.393 123.382 1.00 43.18  ? 185 ILE A HD13 1 
ATOM   2687 N N    . SER A 1 186 ? 114.049 114.076 123.121 1.00 41.78  ? 186 SER A N    1 
ATOM   2688 C CA   . SER A 1 186 ? 112.826 113.445 122.646 1.00 41.78  ? 186 SER A CA   1 
ATOM   2689 C C    . SER A 1 186 ? 112.124 112.703 123.774 1.00 41.78  ? 186 SER A C    1 
ATOM   2690 O O    . SER A 1 186 ? 110.902 112.810 123.933 1.00 41.78  ? 186 SER A O    1 
ATOM   2691 C CB   . SER A 1 186 ? 113.141 112.492 121.495 1.00 41.78  ? 186 SER A CB   1 
ATOM   2692 O OG   . SER A 1 186 ? 112.005 111.722 121.152 1.00 41.78  ? 186 SER A OG   1 
ATOM   2693 H H    . SER A 1 186 ? 114.769 113.817 122.728 1.00 41.78  ? 186 SER A H    1 
ATOM   2694 H HA   . SER A 1 186 ? 112.223 114.129 122.315 1.00 41.78  ? 186 SER A HA   1 
ATOM   2695 H HB2  . SER A 1 186 ? 113.415 113.011 120.722 1.00 41.78  ? 186 SER A HB2  1 
ATOM   2696 H HB3  . SER A 1 186 ? 113.857 111.896 121.766 1.00 41.78  ? 186 SER A HB3  1 
ATOM   2697 H HG   . SER A 1 186 ? 112.180 111.229 120.495 1.00 41.78  ? 186 SER A HG   1 
ATOM   2698 N N    . ALA A 1 187 ? 112.881 111.960 124.583 1.00 44.64  ? 187 ALA A N    1 
ATOM   2699 C CA   . ALA A 1 187 ? 112.274 111.211 125.676 1.00 44.64  ? 187 ALA A CA   1 
ATOM   2700 C C    . ALA A 1 187 ? 111.655 112.144 126.709 1.00 44.64  ? 187 ALA A C    1 
ATOM   2701 O O    . ALA A 1 187 ? 110.524 111.923 127.156 1.00 44.64  ? 187 ALA A O    1 
ATOM   2702 C CB   . ALA A 1 187 ? 113.313 110.302 126.331 1.00 44.64  ? 187 ALA A CB   1 
ATOM   2703 H H    . ALA A 1 187 ? 113.734 111.875 124.518 1.00 44.64  ? 187 ALA A H    1 
ATOM   2704 H HA   . ALA A 1 187 ? 111.568 110.650 125.320 1.00 44.64  ? 187 ALA A HA   1 
ATOM   2705 H HB1  . ALA A 1 187 ? 112.889 109.808 127.050 1.00 44.64  ? 187 ALA A HB1  1 
ATOM   2706 H HB2  . ALA A 1 187 ? 113.659 109.688 125.666 1.00 44.64  ? 187 ALA A HB2  1 
ATOM   2707 H HB3  . ALA A 1 187 ? 114.032 110.849 126.685 1.00 44.64  ? 187 ALA A HB3  1 
ATOM   2708 N N    . VAL A 1 188 ? 112.376 113.195 127.105 1.00 42.91  ? 188 VAL A N    1 
ATOM   2709 C CA   . VAL A 1 188 ? 111.849 114.071 128.147 1.00 42.91  ? 188 VAL A CA   1 
ATOM   2710 C C    . VAL A 1 188 ? 110.613 114.808 127.647 1.00 42.91  ? 188 VAL A C    1 
ATOM   2711 O O    . VAL A 1 188 ? 109.655 115.013 128.400 1.00 42.91  ? 188 VAL A O    1 
ATOM   2712 C CB   . VAL A 1 188 ? 112.928 115.046 128.651 1.00 42.91  ? 188 VAL A CB   1 
ATOM   2713 C CG1  . VAL A 1 188 ? 113.256 116.079 127.603 1.00 42.91  ? 188 VAL A CG1  1 
ATOM   2714 C CG2  . VAL A 1 188 ? 112.470 115.721 129.931 1.00 42.91  ? 188 VAL A CG2  1 
ATOM   2715 H H    . VAL A 1 188 ? 113.148 113.416 126.797 1.00 42.91  ? 188 VAL A H    1 
ATOM   2716 H HA   . VAL A 1 188 ? 111.576 113.523 128.900 1.00 42.91  ? 188 VAL A HA   1 
ATOM   2717 H HB   . VAL A 1 188 ? 113.737 114.548 128.846 1.00 42.91  ? 188 VAL A HB   1 
ATOM   2718 H HG11 . VAL A 1 188 ? 114.027 116.589 127.896 1.00 42.91  ? 188 VAL A HG11 1 
ATOM   2719 H HG12 . VAL A 1 188 ? 113.458 115.621 126.776 1.00 42.91  ? 188 VAL A HG12 1 
ATOM   2720 H HG13 . VAL A 1 188 ? 112.496 116.670 127.481 1.00 42.91  ? 188 VAL A HG13 1 
ATOM   2721 H HG21 . VAL A 1 188 ? 113.190 116.276 130.269 1.00 42.91  ? 188 VAL A HG21 1 
ATOM   2722 H HG22 . VAL A 1 188 ? 111.692 116.268 129.741 1.00 42.91  ? 188 VAL A HG22 1 
ATOM   2723 H HG23 . VAL A 1 188 ? 112.244 115.039 130.584 1.00 42.91  ? 188 VAL A HG23 1 
ATOM   2724 N N    . SER A 1 189 ? 110.607 115.221 126.378 1.00 42.22  ? 189 SER A N    1 
ATOM   2725 C CA   . SER A 1 189 ? 109.411 115.852 125.830 1.00 42.22  ? 189 SER A CA   1 
ATOM   2726 C C    . SER A 1 189 ? 108.250 114.870 125.780 1.00 42.22  ? 189 SER A C    1 
ATOM   2727 O O    . SER A 1 189 ? 107.103 115.238 126.060 1.00 42.22  ? 189 SER A O    1 
ATOM   2728 C CB   . SER A 1 189 ? 109.694 116.404 124.436 1.00 42.22  ? 189 SER A CB   1 
ATOM   2729 O OG   . SER A 1 189 ? 109.640 115.370 123.472 1.00 42.22  ? 189 SER A OG   1 
ATOM   2730 H H    . SER A 1 189 ? 111.264 115.150 125.828 1.00 42.22  ? 189 SER A H    1 
ATOM   2731 H HA   . SER A 1 189 ? 109.153 116.593 126.400 1.00 42.22  ? 189 SER A HA   1 
ATOM   2732 H HB2  . SER A 1 189 ? 109.028 117.075 124.219 1.00 42.22  ? 189 SER A HB2  1 
ATOM   2733 H HB3  . SER A 1 189 ? 110.580 116.799 124.427 1.00 42.22  ? 189 SER A HB3  1 
ATOM   2734 H HG   . SER A 1 189 ? 110.219 114.786 123.645 1.00 42.22  ? 189 SER A HG   1 
ATOM   2735 N N    . GLY A 1 190 ? 108.524 113.615 125.420 1.00 43.62  ? 190 GLY A N    1 
ATOM   2736 C CA   . GLY A 1 190 ? 107.446 112.647 125.297 1.00 43.62  ? 190 GLY A CA   1 
ATOM   2737 C C    . GLY A 1 190 ? 106.703 112.431 126.601 1.00 43.62  ? 190 GLY A C    1 
ATOM   2738 O O    . GLY A 1 190 ? 105.472 112.481 126.642 1.00 43.62  ? 190 GLY A O    1 
ATOM   2739 H H    . GLY A 1 190 ? 109.308 113.309 125.248 1.00 43.62  ? 190 GLY A H    1 
ATOM   2740 H HA2  . GLY A 1 190 ? 106.812 112.954 124.630 1.00 43.62  ? 190 GLY A HA2  1 
ATOM   2741 H HA3  . GLY A 1 190 ? 107.809 111.796 125.007 1.00 43.62  ? 190 GLY A HA3  1 
ATOM   2742 N N    . VAL A 1 191 ? 107.439 112.196 127.688 1.00 44.86  ? 191 VAL A N    1 
ATOM   2743 C CA   . VAL A 1 191 ? 106.784 111.983 128.974 1.00 44.86  ? 191 VAL A CA   1 
ATOM   2744 C C    . VAL A 1 191 ? 106.160 113.278 129.474 1.00 44.86  ? 191 VAL A C    1 
ATOM   2745 O O    . VAL A 1 191 ? 105.071 113.272 130.058 1.00 44.86  ? 191 VAL A O    1 
ATOM   2746 C CB   . VAL A 1 191 ? 107.773 111.397 129.998 1.00 44.86  ? 191 VAL A CB   1 
ATOM   2747 C CG1  . VAL A 1 191 ? 108.891 112.384 130.297 1.00 44.86  ? 191 VAL A CG1  1 
ATOM   2748 C CG2  . VAL A 1 191 ? 107.040 111.015 131.274 1.00 44.86  ? 191 VAL A CG2  1 
ATOM   2749 H H    . VAL A 1 191 ? 108.297 112.156 127.705 1.00 44.86  ? 191 VAL A H    1 
ATOM   2750 H HA   . VAL A 1 191 ? 106.069 111.339 128.856 1.00 44.86  ? 191 VAL A HA   1 
ATOM   2751 H HB   . VAL A 1 191 ? 108.172 110.594 129.629 1.00 44.86  ? 191 VAL A HB   1 
ATOM   2752 H HG11 . VAL A 1 191 ? 109.564 111.939 130.836 1.00 44.86  ? 191 VAL A HG11 1 
ATOM   2753 H HG12 . VAL A 1 191 ? 109.283 112.686 129.464 1.00 44.86  ? 191 VAL A HG12 1 
ATOM   2754 H HG13 . VAL A 1 191 ? 108.527 113.139 130.786 1.00 44.86  ? 191 VAL A HG13 1 
ATOM   2755 H HG21 . VAL A 1 191 ? 107.642 110.512 131.845 1.00 44.86  ? 191 VAL A HG21 1 
ATOM   2756 H HG22 . VAL A 1 191 ? 106.753 111.823 131.729 1.00 44.86  ? 191 VAL A HG22 1 
ATOM   2757 H HG23 . VAL A 1 191 ? 106.270 110.472 131.046 1.00 44.86  ? 191 VAL A HG23 1 
ATOM   2758 N N    . LEU A 1 192 ? 106.838 114.408 129.264 1.00 43.85  ? 192 LEU A N    1 
ATOM   2759 C CA   . LEU A 1 192 ? 106.273 115.687 129.678 1.00 43.85  ? 192 LEU A CA   1 
ATOM   2760 C C    . LEU A 1 192 ? 104.953 115.963 128.974 1.00 43.85  ? 192 LEU A C    1 
ATOM   2761 O O    . LEU A 1 192 ? 104.075 116.624 129.539 1.00 43.85  ? 192 LEU A O    1 
ATOM   2762 C CB   . LEU A 1 192 ? 107.265 116.814 129.399 1.00 43.85  ? 192 LEU A CB   1 
ATOM   2763 C CG   . LEU A 1 192 ? 106.924 118.178 130.000 1.00 43.85  ? 192 LEU A CG   1 
ATOM   2764 C CD1  . LEU A 1 192 ? 106.984 118.127 131.517 1.00 43.85  ? 192 LEU A CD1  1 
ATOM   2765 C CD2  . LEU A 1 192 ? 107.866 119.244 129.468 1.00 43.85  ? 192 LEU A CD2  1 
ATOM   2766 H H    . LEU A 1 192 ? 107.611 114.459 128.890 1.00 43.85  ? 192 LEU A H    1 
ATOM   2767 H HA   . LEU A 1 192 ? 106.104 115.662 130.633 1.00 43.85  ? 192 LEU A HA   1 
ATOM   2768 H HB2  . LEU A 1 192 ? 108.131 116.552 129.749 1.00 43.85  ? 192 LEU A HB2  1 
ATOM   2769 H HB3  . LEU A 1 192 ? 107.329 116.931 128.438 1.00 43.85  ? 192 LEU A HB3  1 
ATOM   2770 H HG   . LEU A 1 192 ? 106.021 118.421 129.745 1.00 43.85  ? 192 LEU A HG   1 
ATOM   2771 H HD11 . LEU A 1 192 ? 106.923 119.030 131.865 1.00 43.85  ? 192 LEU A HD11 1 
ATOM   2772 H HD12 . LEU A 1 192 ? 106.243 117.594 131.848 1.00 43.85  ? 192 LEU A HD12 1 
ATOM   2773 H HD13 . LEU A 1 192 ? 107.826 117.727 131.786 1.00 43.85  ? 192 LEU A HD13 1 
ATOM   2774 H HD21 . LEU A 1 192 ? 107.550 120.115 129.755 1.00 43.85  ? 192 LEU A HD21 1 
ATOM   2775 H HD22 . LEU A 1 192 ? 108.755 119.084 129.820 1.00 43.85  ? 192 LEU A HD22 1 
ATOM   2776 H HD23 . LEU A 1 192 ? 107.880 119.198 128.500 1.00 43.85  ? 192 LEU A HD23 1 
ATOM   2777 N N    . MET A 1 193 ? 104.795 115.471 127.745 1.00 45.07  ? 193 MET A N    1 
ATOM   2778 C CA   . MET A 1 193 ? 103.557 115.697 127.007 1.00 45.07  ? 193 MET A CA   1 
ATOM   2779 C C    . MET A 1 193 ? 102.372 115.032 127.690 1.00 45.07  ? 193 MET A C    1 
ATOM   2780 O O    . MET A 1 193 ? 101.286 115.616 127.769 1.00 45.07  ? 193 MET A O    1 
ATOM   2781 C CB   . MET A 1 193 ? 103.701 115.175 125.579 1.00 45.07  ? 193 MET A CB   1 
ATOM   2782 C CG   . MET A 1 193 ? 102.488 115.421 124.701 1.00 45.07  ? 193 MET A CG   1 
ATOM   2783 S SD   . MET A 1 193 ? 102.603 114.574 123.117 1.00 45.07  ? 193 MET A SD   1 
ATOM   2784 C CE   . MET A 1 193 ? 104.140 115.247 122.493 1.00 45.07  ? 193 MET A CE   1 
ATOM   2785 H H    . MET A 1 193 ? 105.384 115.009 127.321 1.00 45.07  ? 193 MET A H    1 
ATOM   2786 H HA   . MET A 1 193 ? 103.392 116.651 126.959 1.00 45.07  ? 193 MET A HA   1 
ATOM   2787 H HB2  . MET A 1 193 ? 104.460 115.615 125.166 1.00 45.07  ? 193 MET A HB2  1 
ATOM   2788 H HB3  . MET A 1 193 ? 103.854 114.218 125.611 1.00 45.07  ? 193 MET A HB3  1 
ATOM   2789 H HG2  . MET A 1 193 ? 101.690 115.104 125.150 1.00 45.07  ? 193 MET A HG2  1 
ATOM   2790 H HG3  . MET A 1 193 ? 102.414 116.372 124.525 1.00 45.07  ? 193 MET A HG3  1 
ATOM   2791 H HE1  . MET A 1 193 ? 104.235 115.008 121.560 1.00 45.07  ? 193 MET A HE1  1 
ATOM   2792 H HE2  . MET A 1 193 ? 104.124 116.212 122.589 1.00 45.07  ? 193 MET A HE2  1 
ATOM   2793 H HE3  . MET A 1 193 ? 104.877 114.877 123.004 1.00 45.07  ? 193 MET A HE3  1 
ATOM   2794 N N    . ALA A 1 194 ? 102.560 113.816 128.201 1.00 45.98  ? 194 ALA A N    1 
ATOM   2795 C CA   . ALA A 1 194 ? 101.433 113.039 128.698 1.00 45.98  ? 194 ALA A CA   1 
ATOM   2796 C C    . ALA A 1 194 ? 100.721 113.724 129.855 1.00 45.98  ? 194 ALA A C    1 
ATOM   2797 O O    . ALA A 1 194 ? 99.587  113.353 130.173 1.00 45.98  ? 194 ALA A O    1 
ATOM   2798 C CB   . ALA A 1 194 ? 101.902 111.650 129.129 1.00 45.98  ? 194 ALA A CB   1 
ATOM   2799 H H    . ALA A 1 194 ? 103.323 113.425 128.272 1.00 45.98  ? 194 ALA A H    1 
ATOM   2800 H HA   . ALA A 1 194 ? 100.790 112.927 127.981 1.00 45.98  ? 194 ALA A HA   1 
ATOM   2801 H HB1  . ALA A 1 194 ? 101.139 111.146 129.454 1.00 45.98  ? 194 ALA A HB1  1 
ATOM   2802 H HB2  . ALA A 1 194 ? 102.296 111.200 128.365 1.00 45.98  ? 194 ALA A HB2  1 
ATOM   2803 H HB3  . ALA A 1 194 ? 102.561 111.744 129.834 1.00 45.98  ? 194 ALA A HB3  1 
ATOM   2804 N N    . VAL A 1 195 ? 101.353 114.705 130.493 1.00 46.28  ? 195 VAL A N    1 
ATOM   2805 C CA   . VAL A 1 195 ? 100.749 115.431 131.600 1.00 46.28  ? 195 VAL A CA   1 
ATOM   2806 C C    . VAL A 1 195 ? 100.298 116.824 131.162 1.00 46.28  ? 195 VAL A C    1 
ATOM   2807 O O    . VAL A 1 195 ? 100.094 117.701 131.996 1.00 46.28  ? 195 VAL A O    1 
ATOM   2808 C CB   . VAL A 1 195 ? 101.706 115.503 132.802 1.00 46.28  ? 195 VAL A CB   1 
ATOM   2809 C CG1  . VAL A 1 195 ? 100.985 116.030 134.038 1.00 46.28  ? 195 VAL A CG1  1 
ATOM   2810 C CG2  . VAL A 1 195 ? 102.314 114.135 133.080 1.00 46.28  ? 195 VAL A CG2  1 
ATOM   2811 H H    . VAL A 1 195 ? 102.148 114.970 130.301 1.00 46.28  ? 195 VAL A H    1 
ATOM   2812 H HA   . VAL A 1 195 ? 99.959  114.950 131.891 1.00 46.28  ? 195 VAL A HA   1 
ATOM   2813 H HB   . VAL A 1 195 ? 102.429 116.115 132.593 1.00 46.28  ? 195 VAL A HB   1 
ATOM   2814 H HG11 . VAL A 1 195 ? 101.428 115.688 134.830 1.00 46.28  ? 195 VAL A HG11 1 
ATOM   2815 H HG12 . VAL A 1 195 ? 101.019 116.999 134.038 1.00 46.28  ? 195 VAL A HG12 1 
ATOM   2816 H HG13 . VAL A 1 195 ? 100.064 115.727 134.021 1.00 46.28  ? 195 VAL A HG13 1 
ATOM   2817 H HG21 . VAL A 1 195 ? 102.820 114.176 133.906 1.00 46.28  ? 195 VAL A HG21 1 
ATOM   2818 H HG22 . VAL A 1 195 ? 101.599 113.485 133.162 1.00 46.28  ? 195 VAL A HG22 1 
ATOM   2819 H HG23 . VAL A 1 195 ? 102.900 113.892 132.347 1.00 46.28  ? 195 VAL A HG23 1 
ATOM   2820 N N    . ALA A 1 196 ? 100.136 117.039 129.867 1.00 47.38  ? 196 ALA A N    1 
ATOM   2821 C CA   . ALA A 1 196 ? 99.709  118.343 129.374 1.00 47.38  ? 196 ALA A CA   1 
ATOM   2822 C C    . ALA A 1 196 ? 98.249  118.586 129.736 1.00 47.38  ? 196 ALA A C    1 
ATOM   2823 O O    . ALA A 1 196 ? 97.386  117.790 129.345 1.00 47.38  ? 196 ALA A O    1 
ATOM   2824 C CB   . ALA A 1 196 ? 99.899  118.422 127.865 1.00 47.38  ? 196 ALA A CB   1 
ATOM   2825 H H    . ALA A 1 196 ? 100.264 116.453 129.252 1.00 47.38  ? 196 ALA A H    1 
ATOM   2826 H HA   . ALA A 1 196 ? 100.261 119.028 129.779 1.00 47.38  ? 196 ALA A HA   1 
ATOM   2827 H HB1  . ALA A 1 196 ? 99.570  119.279 127.550 1.00 47.38  ? 196 ALA A HB1  1 
ATOM   2828 H HB2  . ALA A 1 196 ? 100.843 118.334 127.660 1.00 47.38  ? 196 ALA A HB2  1 
ATOM   2829 H HB3  . ALA A 1 196 ? 99.400  117.703 127.446 1.00 47.38  ? 196 ALA A HB3  1 
ATOM   2830 N N    . PRO A 1 197 ? 97.922  119.650 130.479 1.00 52.92  ? 197 PRO A N    1 
ATOM   2831 C CA   . PRO A 1 197 ? 96.515  119.905 130.813 1.00 52.92  ? 197 PRO A CA   1 
ATOM   2832 C C    . PRO A 1 197 ? 95.797  120.752 129.775 1.00 52.92  ? 197 PRO A C    1 
ATOM   2833 O O    . PRO A 1 197 ? 94.579  120.636 129.609 1.00 52.92  ? 197 PRO A O    1 
ATOM   2834 C CB   . PRO A 1 197 ? 96.614  120.635 132.154 1.00 52.92  ? 197 PRO A CB   1 
ATOM   2835 C CG   . PRO A 1 197 ? 97.883  121.409 132.037 1.00 52.92  ? 197 PRO A CG   1 
ATOM   2836 C CD   . PRO A 1 197 ? 98.820  120.587 131.177 1.00 52.92  ? 197 PRO A CD   1 
ATOM   2837 H HA   . PRO A 1 197 ? 96.037  119.070 130.936 1.00 52.92  ? 197 PRO A HA   1 
ATOM   2838 H HB2  . PRO A 1 197 ? 95.855  121.229 132.264 1.00 52.92  ? 197 PRO A HB2  1 
ATOM   2839 H HB3  . PRO A 1 197 ? 96.663  119.993 132.879 1.00 52.92  ? 197 PRO A HB3  1 
ATOM   2840 H HG2  . PRO A 1 197 ? 97.701  122.265 131.618 1.00 52.92  ? 197 PRO A HG2  1 
ATOM   2841 H HG3  . PRO A 1 197 ? 98.261  121.540 132.921 1.00 52.92  ? 197 PRO A HG3  1 
ATOM   2842 H HD2  . PRO A 1 197 ? 99.278  121.156 130.538 1.00 52.92  ? 197 PRO A HD2  1 
ATOM   2843 H HD3  . PRO A 1 197 ? 99.448  120.101 131.734 1.00 52.92  ? 197 PRO A HD3  1 
ATOM   2844 N N    . ASP A 1 198 ? 96.537  121.605 129.076 1.00 55.65  ? 198 ASP A N    1 
ATOM   2845 C CA   . ASP A 1 198 ? 95.981  122.551 128.119 1.00 55.65  ? 198 ASP A CA   1 
ATOM   2846 C C    . ASP A 1 198 ? 96.309  122.093 126.699 1.00 55.65  ? 198 ASP A C    1 
ATOM   2847 O O    . ASP A 1 198 ? 96.970  121.074 126.487 1.00 55.65  ? 198 ASP A O    1 
ATOM   2848 C CB   . ASP A 1 198 ? 96.520  123.958 128.394 1.00 55.65  ? 198 ASP A CB   1 
ATOM   2849 C CG   . ASP A 1 198 ? 95.690  125.044 127.734 1.00 55.65  ? 198 ASP A CG   1 
ATOM   2850 O OD1  . ASP A 1 198 ? 94.743  124.706 126.994 1.00 55.65  ? 198 ASP A OD1  1 
ATOM   2851 O OD2  . ASP A 1 198 ? 95.986  126.237 127.956 1.00 55.65  ? 198 ASP A OD2  1 
ATOM   2852 H H    . ASP A 1 198 ? 97.393  121.655 129.142 1.00 55.65  ? 198 ASP A H    1 
ATOM   2853 H HA   . ASP A 1 198 ? 95.016  122.573 128.214 1.00 55.65  ? 198 ASP A HA   1 
ATOM   2854 H HB2  . ASP A 1 198 ? 96.516  124.117 129.350 1.00 55.65  ? 198 ASP A HB2  1 
ATOM   2855 H HB3  . ASP A 1 198 ? 97.424  124.022 128.050 1.00 55.65  ? 198 ASP A HB3  1 
ATOM   2856 N N    . TYR A 1 199 ? 95.826  122.852 125.716 1.00 51.35  ? 199 TYR A N    1 
ATOM   2857 C CA   . TYR A 1 199 ? 96.103  122.545 124.318 1.00 51.35  ? 199 TYR A CA   1 
ATOM   2858 C C    . TYR A 1 199 ? 97.399  123.163 123.818 1.00 51.35  ? 199 TYR A C    1 
ATOM   2859 O O    . TYR A 1 199 ? 98.002  122.633 122.878 1.00 51.35  ? 199 TYR A O    1 
ATOM   2860 C CB   . TYR A 1 199 ? 94.951  123.022 123.434 1.00 51.35  ? 199 TYR A CB   1 
ATOM   2861 C CG   . TYR A 1 199 ? 95.184  122.789 121.961 1.00 51.35  ? 199 TYR A CG   1 
ATOM   2862 C CD1  . TYR A 1 199 ? 94.962  121.545 121.392 1.00 51.35  ? 199 TYR A CD1  1 
ATOM   2863 C CD2  . TYR A 1 199 ? 95.624  123.814 121.138 1.00 51.35  ? 199 TYR A CD2  1 
ATOM   2864 C CE1  . TYR A 1 199 ? 95.171  121.329 120.046 1.00 51.35  ? 199 TYR A CE1  1 
ATOM   2865 C CE2  . TYR A 1 199 ? 95.835  123.606 119.791 1.00 51.35  ? 199 TYR A CE2  1 
ATOM   2866 C CZ   . TYR A 1 199 ? 95.608  122.363 119.251 1.00 51.35  ? 199 TYR A CZ   1 
ATOM   2867 O OH   . TYR A 1 199 ? 95.817  122.154 117.908 1.00 51.35  ? 199 TYR A OH   1 
ATOM   2868 H H    . TYR A 1 199 ? 95.329  123.544 125.828 1.00 51.35  ? 199 TYR A H    1 
ATOM   2869 H HA   . TYR A 1 199 ? 96.174  121.583 124.218 1.00 51.35  ? 199 TYR A HA   1 
ATOM   2870 H HB2  . TYR A 1 199 ? 94.145  122.545 123.686 1.00 51.35  ? 199 TYR A HB2  1 
ATOM   2871 H HB3  . TYR A 1 199 ? 94.826  123.975 123.569 1.00 51.35  ? 199 TYR A HB3  1 
ATOM   2872 H HD1  . TYR A 1 199 ? 94.666  120.845 121.927 1.00 51.35  ? 199 TYR A HD1  1 
ATOM   2873 H HD2  . TYR A 1 199 ? 95.777  124.656 121.500 1.00 51.35  ? 199 TYR A HD2  1 
ATOM   2874 H HE1  . TYR A 1 199 ? 95.018  120.488 119.679 1.00 51.35  ? 199 TYR A HE1  1 
ATOM   2875 H HE2  . TYR A 1 199 ? 96.130  124.304 119.251 1.00 51.35  ? 199 TYR A HE2  1 
ATOM   2876 H HH   . TYR A 1 199 ? 95.541  121.391 117.690 1.00 51.35  ? 199 TYR A HH   1 
ATOM   2877 N N    . THR A 1 200 ? 97.841  124.277 124.405 1.00 49.39  ? 200 THR A N    1 
ATOM   2878 C CA   . THR A 1 200 ? 99.084  124.898 123.959 1.00 49.39  ? 200 THR A CA   1 
ATOM   2879 C C    . THR A 1 200 ? 100.290 124.048 124.340 1.00 49.39  ? 200 THR A C    1 
ATOM   2880 O O    . THR A 1 200 ? 101.210 123.857 123.536 1.00 49.39  ? 200 THR A O    1 
ATOM   2881 C CB   . THR A 1 200 ? 99.216  126.302 124.548 1.00 49.39  ? 200 THR A CB   1 
ATOM   2882 O OG1  . THR A 1 200 ? 99.457  126.209 125.957 1.00 49.39  ? 200 THR A OG1  1 
ATOM   2883 C CG2  . THR A 1 200 ? 97.949  127.107 124.306 1.00 49.39  ? 200 THR A CG2  1 
ATOM   2884 H H    . THR A 1 200 ? 97.446  124.682 125.053 1.00 49.39  ? 200 THR A H    1 
ATOM   2885 H HA   . THR A 1 200 ? 99.068  124.979 122.992 1.00 49.39  ? 200 THR A HA   1 
ATOM   2886 H HB   . THR A 1 200 ? 99.957  126.762 124.124 1.00 49.39  ? 200 THR A HB   1 
ATOM   2887 H HG1  . THR A 1 200 ? 99.572  126.976 126.279 1.00 49.39  ? 200 THR A HG1  1 
ATOM   2888 H HG21 . THR A 1 200 ? 98.111  128.044 124.496 1.00 49.39  ? 200 THR A HG21 1 
ATOM   2889 H HG22 . THR A 1 200 ? 97.670  127.016 123.382 1.00 49.39  ? 200 THR A HG22 1 
ATOM   2890 H HG23 . THR A 1 200 ? 97.237  126.787 124.882 1.00 49.39  ? 200 THR A HG23 1 
ATOM   2891 N N    . SER A 1 201 ? 100.302 123.529 125.570 1.00 50.15  ? 201 SER A N    1 
ATOM   2892 C CA   . SER A 1 201 ? 101.431 122.722 126.017 1.00 50.15  ? 201 SER A CA   1 
ATOM   2893 C C    . SER A 1 201 ? 101.572 121.460 125.176 1.00 50.15  ? 201 SER A C    1 
ATOM   2894 O O    . SER A 1 201 ? 102.690 121.056 124.829 1.00 50.15  ? 201 SER A O    1 
ATOM   2895 C CB   . SER A 1 201 ? 101.263 122.365 127.494 1.00 50.15  ? 201 SER A CB   1 
ATOM   2896 O OG   . SER A 1 201 ? 100.046 121.678 127.714 1.00 50.15  ? 201 SER A OG   1 
ATOM   2897 H H    . SER A 1 201 ? 99.678  123.629 126.153 1.00 50.15  ? 201 SER A H    1 
ATOM   2898 H HA   . SER A 1 201 ? 102.246 123.239 125.924 1.00 50.15  ? 201 SER A HA   1 
ATOM   2899 H HB2  . SER A 1 201 ? 101.999 121.796 127.768 1.00 50.15  ? 201 SER A HB2  1 
ATOM   2900 H HB3  . SER A 1 201 ? 101.263 123.182 128.017 1.00 50.15  ? 201 SER A HB3  1 
ATOM   2901 H HG   . SER A 1 201 ? 99.397  122.156 127.476 1.00 50.15  ? 201 SER A HG   1 
ATOM   2902 N N    . MET A 1 202 ? 100.451 120.816 124.849 1.00 48.57  ? 202 MET A N    1 
ATOM   2903 C CA   . MET A 1 202 ? 100.497 119.637 123.995 1.00 48.57  ? 202 MET A CA   1 
ATOM   2904 C C    . MET A 1 202 ? 101.191 119.955 122.677 1.00 48.57  ? 202 MET A C    1 
ATOM   2905 O O    . MET A 1 202 ? 102.120 119.250 122.258 1.00 48.57  ? 202 MET A O    1 
ATOM   2906 C CB   . MET A 1 202 ? 99.077  119.127 123.750 1.00 48.57  ? 202 MET A CB   1 
ATOM   2907 C CG   . MET A 1 202 ? 98.974  117.960 122.784 1.00 48.57  ? 202 MET A CG   1 
ATOM   2908 S SD   . MET A 1 202 ? 99.747  116.458 123.404 1.00 48.57  ? 202 MET A SD   1 
ATOM   2909 C CE   . MET A 1 202 ? 99.531  115.366 121.999 1.00 48.57  ? 202 MET A CE   1 
ATOM   2910 H H    . MET A 1 202 ? 99.662  121.041 125.107 1.00 48.57  ? 202 MET A H    1 
ATOM   2911 H HA   . MET A 1 202 ? 100.991 118.937 124.449 1.00 48.57  ? 202 MET A HA   1 
ATOM   2912 H HB2  . MET A 1 202 ? 98.699  118.843 124.597 1.00 48.57  ? 202 MET A HB2  1 
ATOM   2913 H HB3  . MET A 1 202 ? 98.548  119.854 123.386 1.00 48.57  ? 202 MET A HB3  1 
ATOM   2914 H HG2  . MET A 1 202 ? 98.036  117.766 122.631 1.00 48.57  ? 202 MET A HG2  1 
ATOM   2915 H HG3  . MET A 1 202 ? 99.399  118.193 121.945 1.00 48.57  ? 202 MET A HG3  1 
ATOM   2916 H HE1  . MET A 1 202 ? 99.823  114.475 122.243 1.00 48.57  ? 202 MET A HE1  1 
ATOM   2917 H HE2  . MET A 1 202 ? 98.592  115.352 121.754 1.00 48.57  ? 202 MET A HE2  1 
ATOM   2918 H HE3  . MET A 1 202 ? 100.060 115.699 121.258 1.00 48.57  ? 202 MET A HE3  1 
ATOM   2919 N N    . LEU A 1 203 ? 100.751 121.025 122.013 1.00 47.24  ? 203 LEU A N    1 
ATOM   2920 C CA   . LEU A 1 203 ? 101.329 121.386 120.725 1.00 47.24  ? 203 LEU A CA   1 
ATOM   2921 C C    . LEU A 1 203 ? 102.811 121.706 120.857 1.00 47.24  ? 203 LEU A C    1 
ATOM   2922 O O    . LEU A 1 203 ? 103.620 121.279 120.028 1.00 47.24  ? 203 LEU A O    1 
ATOM   2923 C CB   . LEU A 1 203 ? 100.579 122.578 120.133 1.00 47.24  ? 203 LEU A CB   1 
ATOM   2924 C CG   . LEU A 1 203 ? 100.960 122.962 118.705 1.00 47.24  ? 203 LEU A CG   1 
ATOM   2925 C CD1  . LEU A 1 203 ? 100.457 121.920 117.729 1.00 47.24  ? 203 LEU A CD1  1 
ATOM   2926 C CD2  . LEU A 1 203 ? 100.411 124.332 118.355 1.00 47.24  ? 203 LEU A CD2  1 
ATOM   2927 H H    . LEU A 1 203 ? 100.127 121.550 122.286 1.00 47.24  ? 203 LEU A H    1 
ATOM   2928 H HA   . LEU A 1 203 ? 101.235 120.637 120.116 1.00 47.24  ? 203 LEU A HA   1 
ATOM   2929 H HB2  . LEU A 1 203 ? 99.630  122.375 120.136 1.00 47.24  ? 203 LEU A HB2  1 
ATOM   2930 H HB3  . LEU A 1 203 ? 100.744 123.352 120.695 1.00 47.24  ? 203 LEU A HB3  1 
ATOM   2931 H HG   . LEU A 1 203 ? 101.926 122.999 118.631 1.00 47.24  ? 203 LEU A HG   1 
ATOM   2932 H HD11 . LEU A 1 203 ? 100.653 122.213 116.826 1.00 47.24  ? 203 LEU A HD11 1 
ATOM   2933 H HD12 . LEU A 1 203 ? 100.902 121.076 117.907 1.00 47.24  ? 203 LEU A HD12 1 
ATOM   2934 H HD13 . LEU A 1 203 ? 99.499  121.822 117.843 1.00 47.24  ? 203 LEU A HD13 1 
ATOM   2935 H HD21 . LEU A 1 203 ? 100.573 124.505 117.415 1.00 47.24  ? 203 LEU A HD21 1 
ATOM   2936 H HD22 . LEU A 1 203 ? 99.458  124.345 118.536 1.00 47.24  ? 203 LEU A HD22 1 
ATOM   2937 H HD23 . LEU A 1 203 ? 100.861 124.999 118.897 1.00 47.24  ? 203 LEU A HD23 1 
ATOM   2938 N N    . LEU A 1 204 ? 103.188 122.451 121.896 1.00 45.74  ? 204 LEU A N    1 
ATOM   2939 C CA   . LEU A 1 204 ? 104.587 122.834 122.055 1.00 45.74  ? 204 LEU A CA   1 
ATOM   2940 C C    . LEU A 1 204 ? 105.471 121.607 122.254 1.00 45.74  ? 204 LEU A C    1 
ATOM   2941 O O    . LEU A 1 204 ? 106.525 121.471 121.614 1.00 45.74  ? 204 LEU A O    1 
ATOM   2942 C CB   . LEU A 1 204 ? 104.724 123.798 123.233 1.00 45.74  ? 204 LEU A CB   1 
ATOM   2943 C CG   . LEU A 1 204 ? 106.086 124.458 123.439 1.00 45.74  ? 204 LEU A CG   1 
ATOM   2944 C CD1  . LEU A 1 204 ? 106.390 125.426 122.310 1.00 45.74  ? 204 LEU A CD1  1 
ATOM   2945 C CD2  . LEU A 1 204 ? 106.128 125.165 124.784 1.00 45.74  ? 204 LEU A CD2  1 
ATOM   2946 H H    . LEU A 1 204 ? 102.663 122.743 122.511 1.00 45.74  ? 204 LEU A H    1 
ATOM   2947 H HA   . LEU A 1 204 ? 104.883 123.291 121.252 1.00 45.74  ? 204 LEU A HA   1 
ATOM   2948 H HB2  . LEU A 1 204 ? 104.077 124.511 123.115 1.00 45.74  ? 204 LEU A HB2  1 
ATOM   2949 H HB3  . LEU A 1 204 ? 104.518 123.311 124.046 1.00 45.74  ? 204 LEU A HB3  1 
ATOM   2950 H HG   . LEU A 1 204 ? 106.773 123.773 123.440 1.00 45.74  ? 204 LEU A HG   1 
ATOM   2951 H HD11 . LEU A 1 204 ? 107.218 125.892 122.510 1.00 45.74  ? 204 LEU A HD11 1 
ATOM   2952 H HD12 . LEU A 1 204 ? 106.482 124.929 121.482 1.00 45.74  ? 204 LEU A HD12 1 
ATOM   2953 H HD13 . LEU A 1 204 ? 105.662 126.064 122.237 1.00 45.74  ? 204 LEU A HD13 1 
ATOM   2954 H HD21 . LEU A 1 204 ? 107.007 125.556 124.908 1.00 45.74  ? 204 LEU A HD21 1 
ATOM   2955 H HD22 . LEU A 1 204 ? 105.452 125.860 124.796 1.00 45.74  ? 204 LEU A HD22 1 
ATOM   2956 H HD23 . LEU A 1 204 ? 105.951 124.519 125.485 1.00 45.74  ? 204 LEU A HD23 1 
ATOM   2957 N N    . PHE A 1 205 ? 105.057 120.698 123.138 1.00 43.43  ? 205 PHE A N    1 
ATOM   2958 C CA   . PHE A 1 205 ? 105.871 119.518 123.398 1.00 43.43  ? 205 PHE A CA   1 
ATOM   2959 C C    . PHE A 1 205 ? 105.964 118.630 122.163 1.00 43.43  ? 205 PHE A C    1 
ATOM   2960 O O    . PHE A 1 205 ? 107.043 118.107 121.848 1.00 43.43  ? 205 PHE A O    1 
ATOM   2961 C CB   . PHE A 1 205 ? 105.307 118.746 124.589 1.00 43.43  ? 205 PHE A CB   1 
ATOM   2962 C CG   . PHE A 1 205 ? 105.339 119.516 125.881 1.00 43.43  ? 205 PHE A CG   1 
ATOM   2963 C CD1  . PHE A 1 205 ? 106.310 120.473 126.117 1.00 43.43  ? 205 PHE A CD1  1 
ATOM   2964 C CD2  . PHE A 1 205 ? 104.393 119.283 126.861 1.00 43.43  ? 205 PHE A CD2  1 
ATOM   2965 C CE1  . PHE A 1 205 ? 106.336 121.177 127.302 1.00 43.43  ? 205 PHE A CE1  1 
ATOM   2966 C CE2  . PHE A 1 205 ? 104.416 119.986 128.047 1.00 43.43  ? 205 PHE A CE2  1 
ATOM   2967 C CZ   . PHE A 1 205 ? 105.387 120.934 128.267 1.00 43.43  ? 205 PHE A CZ   1 
ATOM   2968 H H    . PHE A 1 205 ? 104.327 120.742 123.590 1.00 43.43  ? 205 PHE A H    1 
ATOM   2969 H HA   . PHE A 1 205 ? 106.774 119.798 123.612 1.00 43.43  ? 205 PHE A HA   1 
ATOM   2970 H HB2  . PHE A 1 205 ? 104.384 118.513 124.404 1.00 43.43  ? 205 PHE A HB2  1 
ATOM   2971 H HB3  . PHE A 1 205 ? 105.831 117.939 124.713 1.00 43.43  ? 205 PHE A HB3  1 
ATOM   2972 H HD1  . PHE A 1 205 ? 106.956 120.644 125.471 1.00 43.43  ? 205 PHE A HD1  1 
ATOM   2973 H HD2  . PHE A 1 205 ? 103.733 118.645 126.718 1.00 43.43  ? 205 PHE A HD2  1 
ATOM   2974 H HE1  . PHE A 1 205 ? 106.994 121.817 127.449 1.00 43.43  ? 205 PHE A HE1  1 
ATOM   2975 H HE2  . PHE A 1 205 ? 103.773 119.820 128.698 1.00 43.43  ? 205 PHE A HE2  1 
ATOM   2976 H HZ   . PHE A 1 205 ? 105.403 121.407 129.067 1.00 43.43  ? 205 PHE A HZ   1 
ATOM   2977 N N    . ARG A 1 206 ? 104.853 118.447 121.444 1.00 44.05  ? 206 ARG A N    1 
ATOM   2978 C CA   . ARG A 1 206 ? 104.930 117.662 120.218 1.00 44.05  ? 206 ARG A CA   1 
ATOM   2979 C C    . ARG A 1 206 ? 105.837 118.330 119.197 1.00 44.05  ? 206 ARG A C    1 
ATOM   2980 O O    . ARG A 1 206 ? 106.542 117.643 118.450 1.00 44.05  ? 206 ARG A O    1 
ATOM   2981 C CB   . ARG A 1 206 ? 103.540 117.450 119.627 1.00 44.05  ? 206 ARG A CB   1 
ATOM   2982 C CG   . ARG A 1 206 ? 103.520 116.500 118.441 1.00 44.05  ? 206 ARG A CG   1 
ATOM   2983 C CD   . ARG A 1 206 ? 103.860 115.087 118.867 1.00 44.05  ? 206 ARG A CD   1 
ATOM   2984 N NE   . ARG A 1 206 ? 103.670 114.121 117.795 1.00 44.05  ? 206 ARG A NE   1 
ATOM   2985 C CZ   . ARG A 1 206 ? 103.666 112.807 117.969 1.00 44.05  ? 206 ARG A CZ   1 
ATOM   2986 N NH1  . ARG A 1 206 ? 103.837 112.268 119.165 1.00 44.05  ? 206 ARG A NH1  1 
ATOM   2987 N NH2  . ARG A 1 206 ? 103.479 112.014 116.920 1.00 44.05  ? 206 ARG A NH2  1 
ATOM   2988 H H    . ARG A 1 206 ? 104.074 118.756 121.636 1.00 44.05  ? 206 ARG A H    1 
ATOM   2989 H HA   . ARG A 1 206 ? 105.306 116.793 120.429 1.00 44.05  ? 206 ARG A HA   1 
ATOM   2990 H HB2  . ARG A 1 206 ? 102.962 117.079 120.312 1.00 44.05  ? 206 ARG A HB2  1 
ATOM   2991 H HB3  . ARG A 1 206 ? 103.191 118.304 119.330 1.00 44.05  ? 206 ARG A HB3  1 
ATOM   2992 H HG2  . ARG A 1 206 ? 102.633 116.492 118.050 1.00 44.05  ? 206 ARG A HG2  1 
ATOM   2993 H HG3  . ARG A 1 206 ? 104.173 116.784 117.784 1.00 44.05  ? 206 ARG A HG3  1 
ATOM   2994 H HD2  . ARG A 1 206 ? 104.789 115.051 119.143 1.00 44.05  ? 206 ARG A HD2  1 
ATOM   2995 H HD3  . ARG A 1 206 ? 103.281 114.833 119.602 1.00 44.05  ? 206 ARG A HD3  1 
ATOM   2996 H HE   . ARG A 1 206 ? 103.473 114.422 117.014 1.00 44.05  ? 206 ARG A HE   1 
ATOM   2997 H HH11 . ARG A 1 206 ? 103.959 112.769 119.852 1.00 44.05  ? 206 ARG A HH11 1 
ATOM   2998 H HH12 . ARG A 1 206 ? 103.830 111.412 119.254 1.00 44.05  ? 206 ARG A HH12 1 
ATOM   2999 H HH21 . ARG A 1 206 ? 103.366 112.354 116.138 1.00 44.05  ? 206 ARG A HH21 1 
ATOM   3000 H HH22 . ARG A 1 206 ? 103.474 111.160 117.022 1.00 44.05  ? 206 ARG A HH22 1 
ATOM   3001 N N    . LEU A 1 207 ? 105.838 119.664 119.151 1.00 45.45  ? 207 LEU A N    1 
ATOM   3002 C CA   . LEU A 1 207 ? 106.727 120.367 118.235 1.00 45.45  ? 207 LEU A CA   1 
ATOM   3003 C C    . LEU A 1 207 ? 108.182 120.088 118.573 1.00 45.45  ? 207 LEU A C    1 
ATOM   3004 O O    . LEU A 1 207 ? 108.998 119.837 117.680 1.00 45.45  ? 207 LEU A O    1 
ATOM   3005 C CB   . LEU A 1 207 ? 106.443 121.868 118.286 1.00 45.45  ? 207 LEU A CB   1 
ATOM   3006 C CG   . LEU A 1 207 ? 107.263 122.759 117.353 1.00 45.45  ? 207 LEU A CG   1 
ATOM   3007 C CD1  . LEU A 1 207 ? 107.037 122.373 115.907 1.00 45.45  ? 207 LEU A CD1  1 
ATOM   3008 C CD2  . LEU A 1 207 ? 106.914 124.219 117.573 1.00 45.45  ? 207 LEU A CD2  1 
ATOM   3009 H H    . LEU A 1 207 ? 105.341 120.174 119.632 1.00 45.45  ? 207 LEU A H    1 
ATOM   3010 H HA   . LEU A 1 207 ? 106.561 120.055 117.332 1.00 45.45  ? 207 LEU A HA   1 
ATOM   3011 H HB2  . LEU A 1 207 ? 105.508 122.006 118.064 1.00 45.45  ? 207 LEU A HB2  1 
ATOM   3012 H HB3  . LEU A 1 207 ? 106.606 122.175 119.191 1.00 45.45  ? 207 LEU A HB3  1 
ATOM   3013 H HG   . LEU A 1 207 ? 108.206 122.644 117.551 1.00 45.45  ? 207 LEU A HG   1 
ATOM   3014 H HD11 . LEU A 1 207 ? 107.503 123.003 115.336 1.00 45.45  ? 207 LEU A HD11 1 
ATOM   3015 H HD12 . LEU A 1 207 ? 107.379 121.478 115.763 1.00 45.45  ? 207 LEU A HD12 1 
ATOM   3016 H HD13 . LEU A 1 207 ? 106.085 122.399 115.720 1.00 45.45  ? 207 LEU A HD13 1 
ATOM   3017 H HD21 . LEU A 1 207 ? 107.422 124.762 116.950 1.00 45.45  ? 207 LEU A HD21 1 
ATOM   3018 H HD22 . LEU A 1 207 ? 105.964 124.342 117.420 1.00 45.45  ? 207 LEU A HD22 1 
ATOM   3019 H HD23 . LEU A 1 207 ? 107.137 124.463 118.485 1.00 45.45  ? 207 LEU A HD23 1 
ATOM   3020 N N    . LEU A 1 208 ? 108.525 120.120 119.861 1.00 43.19  ? 208 LEU A N    1 
ATOM   3021 C CA   . LEU A 1 208 ? 109.897 119.813 120.265 1.00 43.19  ? 208 LEU A CA   1 
ATOM   3022 C C    . LEU A 1 208 ? 110.276 118.388 119.869 1.00 43.19  ? 208 LEU A C    1 
ATOM   3023 O O    . LEU A 1 208 ? 111.353 118.140 119.296 1.00 43.19  ? 208 LEU A O    1 
ATOM   3024 C CB   . LEU A 1 208 ? 110.040 120.013 121.773 1.00 43.19  ? 208 LEU A CB   1 
ATOM   3025 C CG   . LEU A 1 208 ? 111.377 119.634 122.403 1.00 43.19  ? 208 LEU A CG   1 
ATOM   3026 C CD1  . LEU A 1 208 ? 112.496 120.474 121.818 1.00 43.19  ? 208 LEU A CD1  1 
ATOM   3027 C CD2  . LEU A 1 208 ? 111.305 119.800 123.912 1.00 43.19  ? 208 LEU A CD2  1 
ATOM   3028 H H    . LEU A 1 208 ? 107.993 120.312 120.509 1.00 43.19  ? 208 LEU A H    1 
ATOM   3029 H HA   . LEU A 1 208 ? 110.504 120.423 119.819 1.00 43.19  ? 208 LEU A HA   1 
ATOM   3030 H HB2  . LEU A 1 208 ? 109.891 120.952 121.967 1.00 43.19  ? 208 LEU A HB2  1 
ATOM   3031 H HB3  . LEU A 1 208 ? 109.357 119.484 122.214 1.00 43.19  ? 208 LEU A HB3  1 
ATOM   3032 H HG   . LEU A 1 208 ? 111.567 118.702 122.214 1.00 43.19  ? 208 LEU A HG   1 
ATOM   3033 H HD11 . LEU A 1 208 ? 113.318 120.276 122.293 1.00 43.19  ? 208 LEU A HD11 1 
ATOM   3034 H HD12 . LEU A 1 208 ? 112.597 120.256 120.878 1.00 43.19  ? 208 LEU A HD12 1 
ATOM   3035 H HD13 . LEU A 1 208 ? 112.273 121.412 121.920 1.00 43.19  ? 208 LEU A HD13 1 
ATOM   3036 H HD21 . LEU A 1 208 ? 112.145 119.509 124.302 1.00 43.19  ? 208 LEU A HD21 1 
ATOM   3037 H HD22 . LEU A 1 208 ? 111.150 120.735 124.120 1.00 43.19  ? 208 LEU A HD22 1 
ATOM   3038 H HD23 . LEU A 1 208 ? 110.577 119.259 124.255 1.00 43.19  ? 208 LEU A HD23 1 
ATOM   3039 N N    . GLN A 1 209 ? 109.389 117.435 120.157 1.00 41.23  ? 209 GLN A N    1 
ATOM   3040 C CA   . GLN A 1 209 ? 109.688 116.043 119.847 1.00 41.23  ? 209 GLN A CA   1 
ATOM   3041 C C    . GLN A 1 209 ? 109.895 115.854 118.350 1.00 41.23  ? 209 GLN A C    1 
ATOM   3042 O O    . GLN A 1 209 ? 110.812 115.140 117.926 1.00 41.23  ? 209 GLN A O    1 
ATOM   3043 C CB   . GLN A 1 209 ? 108.563 115.145 120.353 1.00 41.23  ? 209 GLN A CB   1 
ATOM   3044 C CG   . GLN A 1 209 ? 109.000 113.743 120.712 1.00 41.23  ? 209 GLN A CG   1 
ATOM   3045 C CD   . GLN A 1 209 ? 107.899 112.954 121.385 1.00 41.23  ? 209 GLN A CD   1 
ATOM   3046 O OE1  . GLN A 1 209 ? 108.134 112.257 122.370 1.00 41.23  ? 209 GLN A OE1  1 
ATOM   3047 N NE2  . GLN A 1 209 ? 106.687 113.060 120.858 1.00 41.23  ? 209 GLN A NE2  1 
ATOM   3048 H H    . GLN A 1 209 ? 108.623 117.567 120.524 1.00 41.23  ? 209 GLN A H    1 
ATOM   3049 H HA   . GLN A 1 209 ? 110.506 115.784 120.299 1.00 41.23  ? 209 GLN A HA   1 
ATOM   3050 H HB2  . GLN A 1 209 ? 108.178 115.546 121.148 1.00 41.23  ? 209 GLN A HB2  1 
ATOM   3051 H HB3  . GLN A 1 209 ? 107.887 115.077 119.660 1.00 41.23  ? 209 GLN A HB3  1 
ATOM   3052 H HG2  . GLN A 1 209 ? 109.258 113.273 119.904 1.00 41.23  ? 209 GLN A HG2  1 
ATOM   3053 H HG3  . GLN A 1 209 ? 109.750 113.792 121.324 1.00 41.23  ? 209 GLN A HG3  1 
ATOM   3054 H HE21 . GLN A 1 209 ? 106.029 112.630 121.206 1.00 41.23  ? 209 GLN A HE21 1 
ATOM   3055 H HE22 . GLN A 1 209 ? 106.558 113.556 120.168 1.00 41.23  ? 209 GLN A HE22 1 
ATOM   3056 N N    . GLY A 1 210 ? 109.050 116.485 117.535 1.00 40.71  ? 210 GLY A N    1 
ATOM   3057 C CA   . GLY A 1 210 ? 109.228 116.400 116.096 1.00 40.71  ? 210 GLY A CA   1 
ATOM   3058 C C    . GLY A 1 210 ? 110.518 117.049 115.637 1.00 40.71  ? 210 GLY A C    1 
ATOM   3059 O O    . GLY A 1 210 ? 111.192 116.546 114.736 1.00 40.71  ? 210 GLY A O    1 
ATOM   3060 H H    . GLY A 1 210 ? 108.378 116.959 117.788 1.00 40.71  ? 210 GLY A H    1 
ATOM   3061 H HA2  . GLY A 1 210 ? 109.242 115.467 115.833 1.00 40.71  ? 210 GLY A HA2  1 
ATOM   3062 H HA3  . GLY A 1 210 ? 108.486 116.836 115.650 1.00 40.71  ? 210 GLY A HA3  1 
ATOM   3063 N N    . LEU A 1 211 ? 110.880 118.177 116.250 1.00 43.29  ? 211 LEU A N    1 
ATOM   3064 C CA   . LEU A 1 211 ? 112.142 118.826 115.918 1.00 43.29  ? 211 LEU A CA   1 
ATOM   3065 C C    . LEU A 1 211 ? 113.318 117.885 116.109 1.00 43.29  ? 211 LEU A C    1 
ATOM   3066 O O    . LEU A 1 211 ? 114.264 117.907 115.315 1.00 43.29  ? 211 LEU A O    1 
ATOM   3067 C CB   . LEU A 1 211 ? 112.343 120.069 116.788 1.00 43.29  ? 211 LEU A CB   1 
ATOM   3068 C CG   . LEU A 1 211 ? 112.055 121.451 116.202 1.00 43.29  ? 211 LEU A CG   1 
ATOM   3069 C CD1  . LEU A 1 211 ? 113.006 121.760 115.069 1.00 43.29  ? 211 LEU A CD1  1 
ATOM   3070 C CD2  . LEU A 1 211 ? 110.618 121.561 115.733 1.00 43.29  ? 211 LEU A CD2  1 
ATOM   3071 H H    . LEU A 1 211 ? 110.416 118.580 116.852 1.00 43.29  ? 211 LEU A H    1 
ATOM   3072 H HA   . LEU A 1 211 ? 112.124 119.102 114.989 1.00 43.29  ? 211 LEU A HA   1 
ATOM   3073 H HB2  . LEU A 1 211 ? 111.780 119.975 117.572 1.00 43.29  ? 211 LEU A HB2  1 
ATOM   3074 H HB3  . LEU A 1 211 ? 113.271 120.077 117.072 1.00 43.29  ? 211 LEU A HB3  1 
ATOM   3075 H HG   . LEU A 1 211 ? 112.192 122.117 116.894 1.00 43.29  ? 211 LEU A HG   1 
ATOM   3076 H HD11 . LEU A 1 211 ? 112.938 122.702 114.849 1.00 43.29  ? 211 LEU A HD11 1 
ATOM   3077 H HD12 . LEU A 1 211 ? 112.756 121.222 114.303 1.00 43.29  ? 211 LEU A HD12 1 
ATOM   3078 H HD13 . LEU A 1 211 ? 113.911 121.549 115.347 1.00 43.29  ? 211 LEU A HD13 1 
ATOM   3079 H HD21 . LEU A 1 211 ? 110.380 120.760 115.241 1.00 43.29  ? 211 LEU A HD21 1 
ATOM   3080 H HD22 . LEU A 1 211 ? 110.042 121.659 116.507 1.00 43.29  ? 211 LEU A HD22 1 
ATOM   3081 H HD23 . LEU A 1 211 ? 110.534 122.340 115.161 1.00 43.29  ? 211 LEU A HD23 1 
ATOM   3082 N N    . VAL A 1 212 ? 113.284 117.053 117.148 1.00 43.47  ? 212 VAL A N    1 
ATOM   3083 C CA   . VAL A 1 212 ? 114.489 116.308 117.513 1.00 43.47  ? 212 VAL A CA   1 
ATOM   3084 C C    . VAL A 1 212 ? 114.509 114.882 116.958 1.00 43.47  ? 212 VAL A C    1 
ATOM   3085 O O    . VAL A 1 212 ? 115.585 114.282 116.806 1.00 43.47  ? 212 VAL A O    1 
ATOM   3086 C CB   . VAL A 1 212 ? 114.656 116.296 119.040 1.00 43.47  ? 212 VAL A CB   1 
ATOM   3087 C CG1  . VAL A 1 212 ? 115.901 115.535 119.428 1.00 43.47  ? 212 VAL A CG1  1 
ATOM   3088 C CG2  . VAL A 1 212 ? 114.721 117.720 119.565 1.00 43.47  ? 212 VAL A CG2  1 
ATOM   3089 H H    . VAL A 1 212 ? 112.598 116.902 117.645 1.00 43.47  ? 212 VAL A H    1 
ATOM   3090 H HA   . VAL A 1 212 ? 115.260 116.769 117.146 1.00 43.47  ? 212 VAL A HA   1 
ATOM   3091 H HB   . VAL A 1 212 ? 113.892 115.856 119.443 1.00 43.47  ? 212 VAL A HB   1 
ATOM   3092 H HG11 . VAL A 1 212 ? 116.102 115.724 120.358 1.00 43.47  ? 212 VAL A HG11 1 
ATOM   3093 H HG12 . VAL A 1 212 ? 115.747 114.584 119.313 1.00 43.47  ? 212 VAL A HG12 1 
ATOM   3094 H HG13 . VAL A 1 212 ? 116.637 115.825 118.867 1.00 43.47  ? 212 VAL A HG13 1 
ATOM   3095 H HG21 . VAL A 1 212 ? 115.156 117.723 120.431 1.00 43.47  ? 212 VAL A HG21 1 
ATOM   3096 H HG22 . VAL A 1 212 ? 115.226 118.261 118.939 1.00 43.47  ? 212 VAL A HG22 1 
ATOM   3097 H HG23 . VAL A 1 212 ? 113.819 118.068 119.646 1.00 43.47  ? 212 VAL A HG23 1 
ATOM   3098 N N    . SER A 1 213 ? 113.336 114.324 116.647 1.00 42.31  ? 213 SER A N    1 
ATOM   3099 C CA   . SER A 1 213 ? 113.260 112.890 116.371 1.00 42.31  ? 213 SER A CA   1 
ATOM   3100 C C    . SER A 1 213 ? 114.025 112.502 115.106 1.00 42.31  ? 213 SER A C    1 
ATOM   3101 O O    . SER A 1 213 ? 114.820 111.551 115.119 1.00 42.31  ? 213 SER A O    1 
ATOM   3102 C CB   . SER A 1 213 ? 111.799 112.464 116.259 1.00 42.31  ? 213 SER A CB   1 
ATOM   3103 O OG   . SER A 1 213 ? 111.671 111.062 116.398 1.00 42.31  ? 213 SER A OG   1 
ATOM   3104 H H    . SER A 1 213 ? 112.587 114.743 116.591 1.00 42.31  ? 213 SER A H    1 
ATOM   3105 H HA   . SER A 1 213 ? 113.656 112.407 117.113 1.00 42.31  ? 213 SER A HA   1 
ATOM   3106 H HB2  . SER A 1 213 ? 111.290 112.899 116.960 1.00 42.31  ? 213 SER A HB2  1 
ATOM   3107 H HB3  . SER A 1 213 ? 111.460 112.728 115.389 1.00 42.31  ? 213 SER A HB3  1 
ATOM   3108 H HG   . SER A 1 213 ? 111.956 110.821 117.150 1.00 42.31  ? 213 SER A HG   1 
ATOM   3109 N N    . LYS A 1 214 ? 113.778 113.197 113.993 1.00 44.17  ? 214 LYS A N    1 
ATOM   3110 C CA   . LYS A 1 214 ? 114.414 112.789 112.743 1.00 44.17  ? 214 LYS A CA   1 
ATOM   3111 C C    . LYS A 1 214 ? 115.922 112.963 112.822 1.00 44.17  ? 214 LYS A C    1 
ATOM   3112 O O    . LYS A 1 214 ? 116.678 112.157 112.264 1.00 44.17  ? 214 LYS A O    1 
ATOM   3113 C CB   . LYS A 1 214 ? 113.849 113.570 111.561 1.00 44.17  ? 214 LYS A CB   1 
ATOM   3114 C CG   . LYS A 1 214 ? 114.532 113.221 110.248 1.00 44.17  ? 214 LYS A CG   1 
ATOM   3115 C CD   . LYS A 1 214 ? 113.600 113.361 109.058 1.00 44.17  ? 214 LYS A CD   1 
ATOM   3116 C CE   . LYS A 1 214 ? 113.183 114.801 108.827 1.00 44.17  ? 214 LYS A CE   1 
ATOM   3117 N NZ   . LYS A 1 214 ? 113.489 115.247 107.442 1.00 44.17  ? 214 LYS A NZ   1 
ATOM   3118 H H    . LYS A 1 214 ? 113.267 113.887 113.936 1.00 44.17  ? 214 LYS A H    1 
ATOM   3119 H HA   . LYS A 1 214 ? 114.232 111.849 112.590 1.00 44.17  ? 214 LYS A HA   1 
ATOM   3120 H HB2  . LYS A 1 214 ? 112.903 113.368 111.472 1.00 44.17  ? 214 LYS A HB2  1 
ATOM   3121 H HB3  . LYS A 1 214 ? 113.971 114.519 111.718 1.00 44.17  ? 214 LYS A HB3  1 
ATOM   3122 H HG2  . LYS A 1 214 ? 115.286 113.814 110.107 1.00 44.17  ? 214 LYS A HG2  1 
ATOM   3123 H HG3  . LYS A 1 214 ? 114.835 112.301 110.288 1.00 44.17  ? 214 LYS A HG3  1 
ATOM   3124 H HD2  . LYS A 1 214 ? 114.051 113.042 108.260 1.00 44.17  ? 214 LYS A HD2  1 
ATOM   3125 H HD3  . LYS A 1 214 ? 112.799 112.839 109.219 1.00 44.17  ? 214 LYS A HD3  1 
ATOM   3126 H HE2  . LYS A 1 214 ? 112.226 114.878 108.961 1.00 44.17  ? 214 LYS A HE2  1 
ATOM   3127 H HE3  . LYS A 1 214 ? 113.656 115.379 109.446 1.00 44.17  ? 214 LYS A HE3  1 
ATOM   3128 H HZ1  . LYS A 1 214 ? 114.368 115.303 107.332 1.00 44.17  ? 214 LYS A HZ1  1 
ATOM   3129 H HZ2  . LYS A 1 214 ? 113.163 114.666 106.854 1.00 44.17  ? 214 LYS A HZ2  1 
ATOM   3130 H HZ3  . LYS A 1 214 ? 113.128 116.045 107.288 1.00 44.17  ? 214 LYS A HZ3  1 
ATOM   3131 N N    . GLY A 1 215 ? 116.378 114.013 113.502 1.00 44.35  ? 215 GLY A N    1 
ATOM   3132 C CA   . GLY A 1 215 ? 117.801 114.148 113.748 1.00 44.35  ? 215 GLY A CA   1 
ATOM   3133 C C    . GLY A 1 215 ? 118.363 112.953 114.490 1.00 44.35  ? 215 GLY A C    1 
ATOM   3134 O O    . GLY A 1 215 ? 119.412 112.416 114.120 1.00 44.35  ? 215 GLY A O    1 
ATOM   3135 H H    . GLY A 1 215 ? 115.892 114.646 113.823 1.00 44.35  ? 215 GLY A H    1 
ATOM   3136 H HA2  . GLY A 1 215 ? 118.271 114.243 112.909 1.00 44.35  ? 215 GLY A HA2  1 
ATOM   3137 H HA3  . GLY A 1 215 ? 117.961 114.941 114.282 1.00 44.35  ? 215 GLY A HA3  1 
ATOM   3138 N N    . SER A 1 216 ? 117.664 112.507 115.536 1.00 43.35  ? 216 SER A N    1 
ATOM   3139 C CA   . SER A 1 216 ? 118.122 111.328 116.262 1.00 43.35  ? 216 SER A CA   1 
ATOM   3140 C C    . SER A 1 216 ? 118.239 110.130 115.330 1.00 43.35  ? 216 SER A C    1 
ATOM   3141 O O    . SER A 1 216 ? 119.257 109.426 115.321 1.00 43.35  ? 216 SER A O    1 
ATOM   3142 C CB   . SER A 1 216 ? 117.168 111.013 117.412 1.00 43.35  ? 216 SER A CB   1 
ATOM   3143 O OG   . SER A 1 216 ? 117.474 109.757 117.988 1.00 43.35  ? 216 SER A OG   1 
ATOM   3144 H H    . SER A 1 216 ? 116.940 112.861 115.838 1.00 43.35  ? 216 SER A H    1 
ATOM   3145 H HA   . SER A 1 216 ? 118.999 111.504 116.637 1.00 43.35  ? 216 SER A HA   1 
ATOM   3146 H HB2  . SER A 1 216 ? 117.252 111.700 118.092 1.00 43.35  ? 216 SER A HB2  1 
ATOM   3147 H HB3  . SER A 1 216 ? 116.260 110.991 117.072 1.00 43.35  ? 216 SER A HB3  1 
ATOM   3148 H HG   . SER A 1 216 ? 118.260 109.760 118.286 1.00 43.35  ? 216 SER A HG   1 
ATOM   3149 N N    . TRP A 1 217 ? 117.205 109.893 114.524 1.00 41.58  ? 217 TRP A N    1 
ATOM   3150 C CA   . TRP A 1 217 ? 117.196 108.700 113.681 1.00 41.58  ? 217 TRP A CA   1 
ATOM   3151 C C    . TRP A 1 217 ? 118.322 108.735 112.656 1.00 41.58  ? 217 TRP A C    1 
ATOM   3152 O O    . TRP A 1 217 ? 119.010 107.729 112.443 1.00 41.58  ? 217 TRP A O    1 
ATOM   3153 C CB   . TRP A 1 217 ? 115.848 108.558 112.982 1.00 41.58  ? 217 TRP A CB   1 
ATOM   3154 C CG   . TRP A 1 217 ? 115.702 107.299 112.196 1.00 41.58  ? 217 TRP A CG   1 
ATOM   3155 C CD1  . TRP A 1 217 ? 115.327 106.081 112.669 1.00 41.58  ? 217 TRP A CD1  1 
ATOM   3156 C CD2  . TRP A 1 217 ? 115.911 107.136 110.791 1.00 41.58  ? 217 TRP A CD2  1 
ATOM   3157 N NE1  . TRP A 1 217 ? 115.294 105.165 111.649 1.00 41.58  ? 217 TRP A NE1  1 
ATOM   3158 C CE2  . TRP A 1 217 ? 115.648 105.790 110.484 1.00 41.58  ? 217 TRP A CE2  1 
ATOM   3159 C CE3  . TRP A 1 217 ? 116.297 107.997 109.763 1.00 41.58  ? 217 TRP A CE3  1 
ATOM   3160 C CZ2  . TRP A 1 217 ? 115.760 105.284 109.197 1.00 41.58  ? 217 TRP A CZ2  1 
ATOM   3161 C CZ3  . TRP A 1 217 ? 116.407 107.493 108.486 1.00 41.58  ? 217 TRP A CZ3  1 
ATOM   3162 C CH2  . TRP A 1 217 ? 116.140 106.149 108.213 1.00 41.58  ? 217 TRP A CH2  1 
ATOM   3163 H H    . TRP A 1 217 ? 116.511 110.396 114.445 1.00 41.58  ? 217 TRP A H    1 
ATOM   3164 H HA   . TRP A 1 217 ? 117.326 107.919 114.242 1.00 41.58  ? 217 TRP A HA   1 
ATOM   3165 H HB2  . TRP A 1 217 ? 115.146 108.569 113.652 1.00 41.58  ? 217 TRP A HB2  1 
ATOM   3166 H HB3  . TRP A 1 217 ? 115.732 109.303 112.372 1.00 41.58  ? 217 TRP A HB3  1 
ATOM   3167 H HD1  . TRP A 1 217 ? 115.123 105.895 113.557 1.00 41.58  ? 217 TRP A HD1  1 
ATOM   3168 H HE1  . TRP A 1 217 ? 115.084 104.335 111.728 1.00 41.58  ? 217 TRP A HE1  1 
ATOM   3169 H HE3  . TRP A 1 217 ? 116.476 108.892 109.937 1.00 41.58  ? 217 TRP A HE3  1 
ATOM   3170 H HZ2  . TRP A 1 217 ? 115.583 104.390 109.012 1.00 41.58  ? 217 TRP A HZ2  1 
ATOM   3171 H HZ3  . TRP A 1 217 ? 116.664 108.057 107.793 1.00 41.58  ? 217 TRP A HZ3  1 
ATOM   3172 H HH2  . TRP A 1 217 ? 116.223 105.837 107.341 1.00 41.58  ? 217 TRP A HH2  1 
ATOM   3173 N N    . MET A 1 218 ? 118.541 109.887 112.021 1.00 44.89  ? 218 MET A N    1 
ATOM   3174 C CA   . MET A 1 218 ? 119.566 109.943 110.985 1.00 44.89  ? 218 MET A CA   1 
ATOM   3175 C C    . MET A 1 218 ? 120.966 109.877 111.579 1.00 44.89  ? 218 MET A C    1 
ATOM   3176 O O    . MET A 1 218 ? 121.869 109.283 110.970 1.00 44.89  ? 218 MET A O    1 
ATOM   3177 C CB   . MET A 1 218 ? 119.405 111.211 110.156 1.00 44.89  ? 218 MET A CB   1 
ATOM   3178 C CG   . MET A 1 218 ? 120.055 111.148 108.789 1.00 44.89  ? 218 MET A CG   1 
ATOM   3179 S SD   . MET A 1 218 ? 119.335 109.901 107.703 1.00 44.89  ? 218 MET A SD   1 
ATOM   3180 C CE   . MET A 1 218 ? 117.661 110.510 107.516 1.00 44.89  ? 218 MET A CE   1 
ATOM   3181 H H    . MET A 1 218 ? 118.125 110.625 112.167 1.00 44.89  ? 218 MET A H    1 
ATOM   3182 H HA   . MET A 1 218 ? 119.446 109.183 110.395 1.00 44.89  ? 218 MET A HA   1 
ATOM   3183 H HB2  . MET A 1 218 ? 118.461 111.394 110.035 1.00 44.89  ? 218 MET A HB2  1 
ATOM   3184 H HB3  . MET A 1 218 ? 119.825 111.930 110.644 1.00 44.89  ? 218 MET A HB3  1 
ATOM   3185 H HG2  . MET A 1 218 ? 119.956 112.011 108.358 1.00 44.89  ? 218 MET A HG2  1 
ATOM   3186 H HG3  . MET A 1 218 ? 120.997 110.942 108.899 1.00 44.89  ? 218 MET A HG3  1 
ATOM   3187 H HE1  . MET A 1 218 ? 117.206 110.453 108.371 1.00 44.89  ? 218 MET A HE1  1 
ATOM   3188 H HE2  . MET A 1 218 ? 117.691 111.432 107.217 1.00 44.89  ? 218 MET A HE2  1 
ATOM   3189 H HE3  . MET A 1 218 ? 117.199 109.965 106.860 1.00 44.89  ? 218 MET A HE3  1 
ATOM   3190 N N    . SER A 1 219 ? 121.175 110.466 112.761 1.00 46.72  ? 219 SER A N    1 
ATOM   3191 C CA   . SER A 1 219 ? 122.481 110.346 113.397 1.00 46.72  ? 219 SER A CA   1 
ATOM   3192 C C    . SER A 1 219 ? 122.735 108.919 113.852 1.00 46.72  ? 219 SER A C    1 
ATOM   3193 O O    . SER A 1 219 ? 123.890 108.489 113.923 1.00 46.72  ? 219 SER A O    1 
ATOM   3194 C CB   . SER A 1 219 ? 122.589 111.304 114.580 1.00 46.72  ? 219 SER A CB   1 
ATOM   3195 O OG   . SER A 1 219 ? 121.793 110.862 115.665 1.00 46.72  ? 219 SER A OG   1 
ATOM   3196 H H    . SER A 1 219 ? 120.594 110.925 113.201 1.00 46.72  ? 219 SER A H    1 
ATOM   3197 H HA   . SER A 1 219 ? 123.168 110.583 112.755 1.00 46.72  ? 219 SER A HA   1 
ATOM   3198 H HB2  . SER A 1 219 ? 123.515 111.347 114.868 1.00 46.72  ? 219 SER A HB2  1 
ATOM   3199 H HB3  . SER A 1 219 ? 122.286 112.183 114.304 1.00 46.72  ? 219 SER A HB3  1 
ATOM   3200 H HG   . SER A 1 219 ? 121.846 111.407 116.301 1.00 46.72  ? 219 SER A HG   1 
ATOM   3201 N N    . GLY A 1 220 ? 121.678 108.174 114.173 1.00 47.25  ? 220 GLY A N    1 
ATOM   3202 C CA   . GLY A 1 220 ? 121.849 106.752 114.416 1.00 47.25  ? 220 GLY A CA   1 
ATOM   3203 C C    . GLY A 1 220 ? 122.206 105.992 113.153 1.00 47.25  ? 220 GLY A C    1 
ATOM   3204 O O    . GLY A 1 220 ? 123.042 105.087 113.177 1.00 47.25  ? 220 GLY A O    1 
ATOM   3205 H H    . GLY A 1 220 ? 120.872 108.463 114.253 1.00 47.25  ? 220 GLY A H    1 
ATOM   3206 H HA2  . GLY A 1 220 ? 122.557 106.616 115.066 1.00 47.25  ? 220 GLY A HA2  1 
ATOM   3207 H HA3  . GLY A 1 220 ? 121.027 106.383 114.775 1.00 47.25  ? 220 GLY A HA3  1 
ATOM   3208 N N    . TYR A 1 221 ? 121.581 106.354 112.033 1.00 46.90  ? 221 TYR A N    1 
ATOM   3209 C CA   . TYR A 1 221 ? 121.831 105.651 110.776 1.00 46.90  ? 221 TYR A CA   1 
ATOM   3210 C C    . TYR A 1 221 ? 123.277 105.822 110.323 1.00 46.90  ? 221 TYR A C    1 
ATOM   3211 O O    . TYR A 1 221 ? 123.973 104.838 110.015 1.00 46.90  ? 221 TYR A O    1 
ATOM   3212 C CB   . TYR A 1 221 ? 120.868 106.175 109.709 1.00 46.90  ? 221 TYR A CB   1 
ATOM   3213 C CG   . TYR A 1 221 ? 120.932 105.474 108.375 1.00 46.90  ? 221 TYR A CG   1 
ATOM   3214 C CD1  . TYR A 1 221 ? 121.907 105.792 107.447 1.00 46.90  ? 221 TYR A CD1  1 
ATOM   3215 C CD2  . TYR A 1 221 ? 119.993 104.516 108.033 1.00 46.90  ? 221 TYR A CD2  1 
ATOM   3216 C CE1  . TYR A 1 221 ? 121.957 105.160 106.225 1.00 46.90  ? 221 TYR A CE1  1 
ATOM   3217 C CE2  . TYR A 1 221 ? 120.035 103.881 106.814 1.00 46.90  ? 221 TYR A CE2  1 
ATOM   3218 C CZ   . TYR A 1 221 ? 121.017 104.206 105.914 1.00 46.90  ? 221 TYR A CZ   1 
ATOM   3219 O OH   . TYR A 1 221 ? 121.061 103.572 104.696 1.00 46.90  ? 221 TYR A OH   1 
ATOM   3220 H H    . TYR A 1 221 ? 121.012 106.996 111.974 1.00 46.90  ? 221 TYR A H    1 
ATOM   3221 H HA   . TYR A 1 221 ? 121.660 104.704 110.899 1.00 46.90  ? 221 TYR A HA   1 
ATOM   3222 H HB2  . TYR A 1 221 ? 119.962 106.084 110.042 1.00 46.90  ? 221 TYR A HB2  1 
ATOM   3223 H HB3  . TYR A 1 221 ? 121.063 107.113 109.554 1.00 46.90  ? 221 TYR A HB3  1 
ATOM   3224 H HD1  . TYR A 1 221 ? 122.544 106.436 107.655 1.00 46.90  ? 221 TYR A HD1  1 
ATOM   3225 H HD2  . TYR A 1 221 ? 119.326 104.292 108.641 1.00 46.90  ? 221 TYR A HD2  1 
ATOM   3226 H HE1  . TYR A 1 221 ? 122.622 105.379 105.612 1.00 46.90  ? 221 TYR A HE1  1 
ATOM   3227 H HE2  . TYR A 1 221 ? 119.401 103.234 106.601 1.00 46.90  ? 221 TYR A HE2  1 
ATOM   3228 H HH   . TYR A 1 221 ? 121.729 103.834 104.259 1.00 46.90  ? 221 TYR A HH   1 
ATOM   3229 N N    . THR A 1 222 ? 123.750 107.069 110.288 1.00 49.79  ? 222 THR A N    1 
ATOM   3230 C CA   . THR A 1 222 ? 125.088 107.328 109.767 1.00 49.79  ? 222 THR A CA   1 
ATOM   3231 C C    . THR A 1 222 ? 126.147 106.618 110.599 1.00 49.79  ? 222 THR A C    1 
ATOM   3232 O O    . THR A 1 222 ? 127.185 106.204 110.072 1.00 49.79  ? 222 THR A O    1 
ATOM   3233 C CB   . THR A 1 222 ? 125.364 108.830 109.725 1.00 49.79  ? 222 THR A CB   1 
ATOM   3234 O OG1  . THR A 1 222 ? 126.605 109.067 109.053 1.00 49.79  ? 222 THR A OG1  1 
ATOM   3235 C CG2  . THR A 1 222 ? 125.448 109.403 111.126 1.00 49.79  ? 222 THR A CG2  1 
ATOM   3236 H H    . THR A 1 222 ? 123.324 107.768 110.554 1.00 49.79  ? 222 THR A H    1 
ATOM   3237 H HA   . THR A 1 222 ? 125.143 106.988 108.860 1.00 49.79  ? 222 THR A HA   1 
ATOM   3238 H HB   . THR A 1 222 ? 124.647 109.279 109.250 1.00 49.79  ? 222 THR A HB   1 
ATOM   3239 H HG1  . THR A 1 222 ? 126.776 109.889 109.045 1.00 49.79  ? 222 THR A HG1  1 
ATOM   3240 H HG21 . THR A 1 222 ? 125.391 110.371 111.092 1.00 49.79  ? 222 THR A HG21 1 
ATOM   3241 H HG22 . THR A 1 222 ? 124.718 109.064 111.667 1.00 49.79  ? 222 THR A HG22 1 
ATOM   3242 H HG23 . THR A 1 222 ? 126.288 109.152 111.539 1.00 49.79  ? 222 THR A HG23 1 
ATOM   3243 N N    . LEU A 1 223 ? 125.903 106.465 111.901 1.00 52.48  ? 223 LEU A N    1 
ATOM   3244 C CA   . LEU A 1 223 ? 126.907 105.865 112.774 1.00 52.48  ? 223 LEU A CA   1 
ATOM   3245 C C    . LEU A 1 223 ? 127.199 104.425 112.371 1.00 52.48  ? 223 LEU A C    1 
ATOM   3246 O O    . LEU A 1 223 ? 128.359 104.049 112.169 1.00 52.48  ? 223 LEU A O    1 
ATOM   3247 C CB   . LEU A 1 223 ? 126.441 105.937 114.226 1.00 52.48  ? 223 LEU A CB   1 
ATOM   3248 C CG   . LEU A 1 223 ? 127.418 105.405 115.273 1.00 52.48  ? 223 LEU A CG   1 
ATOM   3249 C CD1  . LEU A 1 223 ? 128.772 106.057 115.124 1.00 52.48  ? 223 LEU A CD1  1 
ATOM   3250 C CD2  . LEU A 1 223 ? 126.869 105.637 116.666 1.00 52.48  ? 223 LEU A CD2  1 
ATOM   3251 H H    . LEU A 1 223 ? 125.175 106.696 112.297 1.00 52.48  ? 223 LEU A H    1 
ATOM   3252 H HA   . LEU A 1 223 ? 127.730 106.372 112.692 1.00 52.48  ? 223 LEU A HA   1 
ATOM   3253 H HB2  . LEU A 1 223 ? 126.261 106.865 114.444 1.00 52.48  ? 223 LEU A HB2  1 
ATOM   3254 H HB3  . LEU A 1 223 ? 125.623 105.423 114.309 1.00 52.48  ? 223 LEU A HB3  1 
ATOM   3255 H HG   . LEU A 1 223 ? 127.528 104.449 115.148 1.00 52.48  ? 223 LEU A HG   1 
ATOM   3256 H HD11 . LEU A 1 223 ? 129.318 105.829 115.893 1.00 52.48  ? 223 LEU A HD11 1 
ATOM   3257 H HD12 . LEU A 1 223 ? 129.190 105.727 114.314 1.00 52.48  ? 223 LEU A HD12 1 
ATOM   3258 H HD13 . LEU A 1 223 ? 128.658 107.019 115.073 1.00 52.48  ? 223 LEU A HD13 1 
ATOM   3259 H HD21 . LEU A 1 223 ? 127.476 105.244 117.313 1.00 52.48  ? 223 LEU A HD21 1 
ATOM   3260 H HD22 . LEU A 1 223 ? 126.793 106.592 116.820 1.00 52.48  ? 223 LEU A HD22 1 
ATOM   3261 H HD23 . LEU A 1 223 ? 125.996 105.219 116.734 1.00 52.48  ? 223 LEU A HD23 1 
ATOM   3262 N N    . ILE A 1 224 ? 126.159 103.600 112.242 1.00 50.52  ? 224 ILE A N    1 
ATOM   3263 C CA   . ILE A 1 224 ? 126.385 102.217 111.837 1.00 50.52  ? 224 ILE A CA   1 
ATOM   3264 C C    . ILE A 1 224 ? 126.908 102.164 110.410 1.00 50.52  ? 224 ILE A C    1 
ATOM   3265 O O    . ILE A 1 224 ? 127.774 101.339 110.084 1.00 50.52  ? 224 ILE A O    1 
ATOM   3266 C CB   . ILE A 1 224 ? 125.109 101.372 112.004 1.00 50.52  ? 224 ILE A CB   1 
ATOM   3267 C CG1  . ILE A 1 224 ? 123.989 101.891 111.103 1.00 50.52  ? 224 ILE A CG1  1 
ATOM   3268 C CG2  . ILE A 1 224 ? 124.666 101.375 113.445 1.00 50.52  ? 224 ILE A CG2  1 
ATOM   3269 C CD1  . ILE A 1 224 ? 122.689 101.145 111.265 1.00 50.52  ? 224 ILE A CD1  1 
ATOM   3270 H H    . ILE A 1 224 ? 125.337 103.810 112.383 1.00 50.52  ? 224 ILE A H    1 
ATOM   3271 H HA   . ILE A 1 224 ? 127.066 101.834 112.413 1.00 50.52  ? 224 ILE A HA   1 
ATOM   3272 H HB   . ILE A 1 224 ? 125.310 100.458 111.747 1.00 50.52  ? 224 ILE A HB   1 
ATOM   3273 H HG12 . ILE A 1 224 ? 123.822 102.822 111.315 1.00 50.52  ? 224 ILE A HG12 1 
ATOM   3274 H HG13 . ILE A 1 224 ? 124.260 101.806 110.176 1.00 50.52  ? 224 ILE A HG13 1 
ATOM   3275 H HG21 . ILE A 1 224 ? 124.011 100.672 113.581 1.00 50.52  ? 224 ILE A HG21 1 
ATOM   3276 H HG22 . ILE A 1 224 ? 125.437 101.223 114.014 1.00 50.52  ? 224 ILE A HG22 1 
ATOM   3277 H HG23 . ILE A 1 224 ? 124.274 102.239 113.641 1.00 50.52  ? 224 ILE A HG23 1 
ATOM   3278 H HD11 . ILE A 1 224 ? 122.101 101.371 110.527 1.00 50.52  ? 224 ILE A HD11 1 
ATOM   3279 H HD12 . ILE A 1 224 ? 122.867 100.192 111.267 1.00 50.52  ? 224 ILE A HD12 1 
ATOM   3280 H HD13 . ILE A 1 224 ? 122.282 101.406 112.106 1.00 50.52  ? 224 ILE A HD13 1 
ATOM   3281 N N    . THR A 1 225 ? 126.405 103.041 109.531 1.00 50.66  ? 225 THR A N    1 
ATOM   3282 C CA   . THR A 1 225 ? 126.909 103.020 108.162 1.00 50.66  ? 225 THR A CA   1 
ATOM   3283 C C    . THR A 1 225 ? 128.417 103.234 108.136 1.00 50.66  ? 225 THR A C    1 
ATOM   3284 O O    . THR A 1 225 ? 129.132 102.570 107.380 1.00 50.66  ? 225 THR A O    1 
ATOM   3285 C CB   . THR A 1 225 ? 126.203 104.074 107.312 1.00 50.66  ? 225 THR A CB   1 
ATOM   3286 O OG1  . THR A 1 225 ? 124.832 103.703 107.133 1.00 50.66  ? 225 THR A OG1  1 
ATOM   3287 C CG2  . THR A 1 225 ? 126.865 104.195 105.951 1.00 50.66  ? 225 THR A CG2  1 
ATOM   3288 H H    . THR A 1 225 ? 125.801 103.630 109.697 1.00 50.66  ? 225 THR A H    1 
ATOM   3289 H HA   . THR A 1 225 ? 126.724 102.151 107.773 1.00 50.66  ? 225 THR A HA   1 
ATOM   3290 H HB   . THR A 1 225 ? 126.251 104.936 107.756 1.00 50.66  ? 225 THR A HB   1 
ATOM   3291 H HG1  . THR A 1 225 ? 124.438 103.688 107.875 1.00 50.66  ? 225 THR A HG1  1 
ATOM   3292 H HG21 . THR A 1 225 ? 126.267 104.642 105.332 1.00 50.66  ? 225 THR A HG21 1 
ATOM   3293 H HG22 . THR A 1 225 ? 127.685 104.708 106.020 1.00 50.66  ? 225 THR A HG22 1 
ATOM   3294 H HG23 . THR A 1 225 ? 127.071 103.312 105.604 1.00 50.66  ? 225 THR A HG23 1 
ATOM   3295 N N    . GLU A 1 226 ? 128.920 104.153 108.962 1.00 56.01  ? 226 GLU A N    1 
ATOM   3296 C CA   . GLU A 1 226 ? 130.364 104.349 109.048 1.00 56.01  ? 226 GLU A CA   1 
ATOM   3297 C C    . GLU A 1 226 ? 131.050 103.151 109.690 1.00 56.01  ? 226 GLU A C    1 
ATOM   3298 O O    . GLU A 1 226 ? 132.114 102.721 109.232 1.00 56.01  ? 226 GLU A O    1 
ATOM   3299 C CB   . GLU A 1 226 ? 130.677 105.622 109.833 1.00 56.01  ? 226 GLU A CB   1 
ATOM   3300 C CG   . GLU A 1 226 ? 130.490 106.901 109.040 1.00 56.01  ? 226 GLU A CG   1 
ATOM   3301 C CD   . GLU A 1 226 ? 130.575 108.139 109.904 1.00 56.01  ? 226 GLU A CD   1 
ATOM   3302 O OE1  . GLU A 1 226 ? 130.874 108.004 111.107 1.00 56.01  ? 226 GLU A OE1  1 
ATOM   3303 O OE2  . GLU A 1 226 ? 130.339 109.249 109.386 1.00 56.01  ? 226 GLU A OE2  1 
ATOM   3304 H H    . GLU A 1 226 ? 128.455 104.664 109.474 1.00 56.01  ? 226 GLU A H    1 
ATOM   3305 H HA   . GLU A 1 226 ? 130.723 104.453 108.153 1.00 56.01  ? 226 GLU A HA   1 
ATOM   3306 H HB2  . GLU A 1 226 ? 130.089 105.664 110.603 1.00 56.01  ? 226 GLU A HB2  1 
ATOM   3307 H HB3  . GLU A 1 226 ? 131.601 105.588 110.129 1.00 56.01  ? 226 GLU A HB3  1 
ATOM   3308 H HG2  . GLU A 1 226 ? 131.186 106.958 108.365 1.00 56.01  ? 226 GLU A HG2  1 
ATOM   3309 H HG3  . GLU A 1 226 ? 129.617 106.888 108.618 1.00 56.01  ? 226 GLU A HG3  1 
ATOM   3310 N N    . PHE A 1 227 ? 130.461 102.600 110.754 1.00 58.23  ? 227 PHE A N    1 
ATOM   3311 C CA   . PHE A 1 227 ? 131.136 101.541 111.500 1.00 58.23  ? 227 PHE A CA   1 
ATOM   3312 C C    . PHE A 1 227 ? 131.364 100.305 110.642 1.00 58.23  ? 227 PHE A C    1 
ATOM   3313 O O    . PHE A 1 227 ? 132.456 99.726  110.656 1.00 58.23  ? 227 PHE A O    1 
ATOM   3314 C CB   . PHE A 1 227 ? 130.324 101.164 112.737 1.00 58.23  ? 227 PHE A CB   1 
ATOM   3315 C CG   . PHE A 1 227 ? 130.889 101.694 114.017 1.00 58.23  ? 227 PHE A CG   1 
ATOM   3316 C CD1  . PHE A 1 227 ? 132.108 101.245 114.487 1.00 58.23  ? 227 PHE A CD1  1 
ATOM   3317 C CD2  . PHE A 1 227 ? 130.194 102.629 114.759 1.00 58.23  ? 227 PHE A CD2  1 
ATOM   3318 C CE1  . PHE A 1 227 ? 132.628 101.727 115.666 1.00 58.23  ? 227 PHE A CE1  1 
ATOM   3319 C CE2  . PHE A 1 227 ? 130.708 103.113 115.938 1.00 58.23  ? 227 PHE A CE2  1 
ATOM   3320 C CZ   . PHE A 1 227 ? 131.927 102.662 116.393 1.00 58.23  ? 227 PHE A CZ   1 
ATOM   3321 H H    . PHE A 1 227 ? 129.686 102.817 111.056 1.00 58.23  ? 227 PHE A H    1 
ATOM   3322 H HA   . PHE A 1 227 ? 132.002 101.866 111.793 1.00 58.23  ? 227 PHE A HA   1 
ATOM   3323 H HB2  . PHE A 1 227 ? 129.425 101.514 112.642 1.00 58.23  ? 227 PHE A HB2  1 
ATOM   3324 H HB3  . PHE A 1 227 ? 130.294 100.197 112.806 1.00 58.23  ? 227 PHE A HB3  1 
ATOM   3325 H HD1  . PHE A 1 227 ? 132.585 100.614 113.998 1.00 58.23  ? 227 PHE A HD1  1 
ATOM   3326 H HD2  . PHE A 1 227 ? 129.371 102.937 114.455 1.00 58.23  ? 227 PHE A HD2  1 
ATOM   3327 H HE1  . PHE A 1 227 ? 133.451 101.421 115.972 1.00 58.23  ? 227 PHE A HE1  1 
ATOM   3328 H HE2  . PHE A 1 227 ? 130.233 103.745 116.428 1.00 58.23  ? 227 PHE A HE2  1 
ATOM   3329 H HZ   . PHE A 1 227 ? 132.276 102.989 117.190 1.00 58.23  ? 227 PHE A HZ   1 
ATOM   3330 N N    . VAL A 1 228 ? 130.348 99.880  109.891 1.00 55.70  ? 228 VAL A N    1 
ATOM   3331 C CA   . VAL A 1 228 ? 130.462 98.608  109.182 1.00 55.70  ? 228 VAL A CA   1 
ATOM   3332 C C    . VAL A 1 228 ? 131.473 98.730  108.047 1.00 55.70  ? 228 VAL A C    1 
ATOM   3333 O O    . VAL A 1 228 ? 131.818 99.824  107.589 1.00 55.70  ? 228 VAL A O    1 
ATOM   3334 C CB   . VAL A 1 228 ? 129.089 98.153  108.661 1.00 55.70  ? 228 VAL A CB   1 
ATOM   3335 C CG1  . VAL A 1 228 ? 128.654 99.010  107.485 1.00 55.70  ? 228 VAL A CG1  1 
ATOM   3336 C CG2  . VAL A 1 228 ? 129.126 96.683  108.279 1.00 55.70  ? 228 VAL A CG2  1 
ATOM   3337 H H    . VAL A 1 228 ? 129.604 100.295 109.778 1.00 55.70  ? 228 VAL A H    1 
ATOM   3338 H HA   . VAL A 1 228 ? 130.786 97.933  109.799 1.00 55.70  ? 228 VAL A HA   1 
ATOM   3339 H HB   . VAL A 1 228 ? 128.435 98.261  109.368 1.00 55.70  ? 228 VAL A HB   1 
ATOM   3340 H HG11 . VAL A 1 228 ? 127.701 98.894  107.348 1.00 55.70  ? 228 VAL A HG11 1 
ATOM   3341 H HG12 . VAL A 1 228 ? 128.849 99.939  107.684 1.00 55.70  ? 228 VAL A HG12 1 
ATOM   3342 H HG13 . VAL A 1 228 ? 129.138 98.732  106.692 1.00 55.70  ? 228 VAL A HG13 1 
ATOM   3343 H HG21 . VAL A 1 228 ? 129.655 96.577  107.474 1.00 55.70  ? 228 VAL A HG21 1 
ATOM   3344 H HG22 . VAL A 1 228 ? 128.220 96.378  108.117 1.00 55.70  ? 228 VAL A HG22 1 
ATOM   3345 H HG23 . VAL A 1 228 ? 129.519 96.176  109.006 1.00 55.70  ? 228 VAL A HG23 1 
ATOM   3346 N N    . GLY A 1 229 ? 131.957 97.581  107.589 1.00 59.85  ? 229 GLY A N    1 
ATOM   3347 C CA   . GLY A 1 229 ? 132.908 97.556  106.499 1.00 59.85  ? 229 GLY A CA   1 
ATOM   3348 C C    . GLY A 1 229 ? 132.297 98.058  105.205 1.00 59.85  ? 229 GLY A C    1 
ATOM   3349 O O    . GLY A 1 229 ? 131.088 98.246  105.076 1.00 59.85  ? 229 GLY A O    1 
ATOM   3350 H H    . GLY A 1 229 ? 131.747 96.804  107.895 1.00 59.85  ? 229 GLY A H    1 
ATOM   3351 H HA2  . GLY A 1 229 ? 133.669 98.116  106.719 1.00 59.85  ? 229 GLY A HA2  1 
ATOM   3352 H HA3  . GLY A 1 229 ? 133.221 96.649  106.361 1.00 59.85  ? 229 GLY A HA3  1 
ATOM   3353 N N    . SER A 1 230 ? 133.168 98.289  104.221 1.00 60.01  ? 230 SER A N    1 
ATOM   3354 C CA   . SER A 1 230 ? 132.710 98.856  102.956 1.00 60.01  ? 230 SER A CA   1 
ATOM   3355 C C    . SER A 1 230 ? 131.742 97.921  102.244 1.00 60.01  ? 230 SER A C    1 
ATOM   3356 O O    . SER A 1 230 ? 130.759 98.372  101.646 1.00 60.01  ? 230 SER A O    1 
ATOM   3357 C CB   . SER A 1 230 ? 133.903 99.173  102.057 1.00 60.01  ? 230 SER A CB   1 
ATOM   3358 O OG   . SER A 1 230 ? 134.613 97.995  101.720 1.00 60.01  ? 230 SER A OG   1 
ATOM   3359 H H    . SER A 1 230 ? 134.012 98.129  104.259 1.00 60.01  ? 230 SER A H    1 
ATOM   3360 H HA   . SER A 1 230 ? 132.243 99.687  103.138 1.00 60.01  ? 230 SER A HA   1 
ATOM   3361 H HB2  . SER A 1 230 ? 133.582 99.589  101.242 1.00 60.01  ? 230 SER A HB2  1 
ATOM   3362 H HB3  . SER A 1 230 ? 134.499 99.778  102.525 1.00 60.01  ? 230 SER A HB3  1 
ATOM   3363 H HG   . SER A 1 230 ? 135.280 98.187  101.246 1.00 60.01  ? 230 SER A HG   1 
ATOM   3364 N N    . GLY A 1 231 ? 132.010 96.614  102.281 1.00 53.34  ? 231 GLY A N    1 
ATOM   3365 C CA   . GLY A 1 231 ? 131.186 95.676  101.539 1.00 53.34  ? 231 GLY A CA   1 
ATOM   3366 C C    . GLY A 1 231 ? 129.853 95.365  102.183 1.00 53.34  ? 231 GLY A C    1 
ATOM   3367 O O    . GLY A 1 231 ? 128.890 95.038  101.483 1.00 53.34  ? 231 GLY A O    1 
ATOM   3368 H H    . GLY A 1 231 ? 132.654 96.255  102.724 1.00 53.34  ? 231 GLY A H    1 
ATOM   3369 H HA2  . GLY A 1 231 ? 131.016 96.036  100.655 1.00 53.34  ? 231 GLY A HA2  1 
ATOM   3370 H HA3  . GLY A 1 231 ? 131.672 94.843  101.436 1.00 53.34  ? 231 GLY A HA3  1 
ATOM   3371 N N    . TYR A 1 232 ? 129.765 95.467  103.509 1.00 53.63  ? 232 TYR A N    1 
ATOM   3372 C CA   . TYR A 1 232 ? 128.588 95.039  104.252 1.00 53.63  ? 232 TYR A CA   1 
ATOM   3373 C C    . TYR A 1 232 ? 127.641 96.190  104.573 1.00 53.63  ? 232 TYR A C    1 
ATOM   3374 O O    . TYR A 1 232 ? 126.871 96.098  105.533 1.00 53.63  ? 232 TYR A O    1 
ATOM   3375 C CB   . TYR A 1 232 ? 129.013 94.344  105.546 1.00 53.63  ? 232 TYR A CB   1 
ATOM   3376 C CG   . TYR A 1 232 ? 129.577 92.956  105.353 1.00 53.63  ? 232 TYR A CG   1 
ATOM   3377 C CD1  . TYR A 1 232 ? 130.710 92.745  104.583 1.00 53.63  ? 232 TYR A CD1  1 
ATOM   3378 C CD2  . TYR A 1 232 ? 128.985 91.858  105.958 1.00 53.63  ? 232 TYR A CD2  1 
ATOM   3379 C CE1  . TYR A 1 232 ? 131.230 91.479  104.410 1.00 53.63  ? 232 TYR A CE1  1 
ATOM   3380 C CE2  . TYR A 1 232 ? 129.498 90.590  105.793 1.00 53.63  ? 232 TYR A CE2  1 
ATOM   3381 C CZ   . TYR A 1 232 ? 130.621 90.406  105.018 1.00 53.63  ? 232 TYR A CZ   1 
ATOM   3382 O OH   . TYR A 1 232 ? 131.137 89.143  104.848 1.00 53.63  ? 232 TYR A OH   1 
ATOM   3383 H H    . TYR A 1 232 ? 130.388 95.788  104.007 1.00 53.63  ? 232 TYR A H    1 
ATOM   3384 H HA   . TYR A 1 232 ? 128.099 94.395  103.718 1.00 53.63  ? 232 TYR A HA   1 
ATOM   3385 H HB2  . TYR A 1 232 ? 129.696 94.880  105.976 1.00 53.63  ? 232 TYR A HB2  1 
ATOM   3386 H HB3  . TYR A 1 232 ? 128.242 94.265  106.129 1.00 53.63  ? 232 TYR A HB3  1 
ATOM   3387 H HD1  . TYR A 1 232 ? 131.123 93.468  104.169 1.00 53.63  ? 232 TYR A HD1  1 
ATOM   3388 H HD2  . TYR A 1 232 ? 128.226 91.979  106.482 1.00 53.63  ? 232 TYR A HD2  1 
ATOM   3389 H HE1  . TYR A 1 232 ? 131.988 91.352  103.887 1.00 53.63  ? 232 TYR A HE1  1 
ATOM   3390 H HE2  . TYR A 1 232 ? 129.088 89.862  106.202 1.00 53.63  ? 232 TYR A HE2  1 
ATOM   3391 H HH   . TYR A 1 232 ? 130.646 88.579  105.230 1.00 53.63  ? 232 TYR A HH   1 
ATOM   3392 N N    . ARG A 1 233 ? 127.677 97.273  103.795 1.00 53.68  ? 233 ARG A N    1 
ATOM   3393 C CA   . ARG A 1 233 ? 126.780 98.390  104.071 1.00 53.68  ? 233 ARG A CA   1 
ATOM   3394 C C    . ARG A 1 233 ? 125.332 98.025  103.769 1.00 53.68  ? 233 ARG A C    1 
ATOM   3395 O O    . ARG A 1 233 ? 124.415 98.452  104.485 1.00 53.68  ? 233 ARG A O    1 
ATOM   3396 C CB   . ARG A 1 233 ? 127.198 99.618  103.263 1.00 53.68  ? 233 ARG A CB   1 
ATOM   3397 C CG   . ARG A 1 233 ? 128.491 100.259 103.731 1.00 53.68  ? 233 ARG A CG   1 
ATOM   3398 C CD   . ARG A 1 233 ? 128.680 101.632 103.110 1.00 53.68  ? 233 ARG A CD   1 
ATOM   3399 N NE   . ARG A 1 233 ? 128.779 101.569 101.657 1.00 53.68  ? 233 ARG A NE   1 
ATOM   3400 C CZ   . ARG A 1 233 ? 129.915 101.444 100.985 1.00 53.68  ? 233 ARG A CZ   1 
ATOM   3401 N NH1  . ARG A 1 233 ? 131.082 101.361 101.604 1.00 53.68  ? 233 ARG A NH1  1 
ATOM   3402 N NH2  . ARG A 1 233 ? 129.882 101.401 99.656  1.00 53.68  ? 233 ARG A NH2  1 
ATOM   3403 H H    . ARG A 1 233 ? 128.198 97.383  103.120 1.00 53.68  ? 233 ARG A H    1 
ATOM   3404 H HA   . ARG A 1 233 ? 126.841 98.617  105.012 1.00 53.68  ? 233 ARG A HA   1 
ATOM   3405 H HB2  . ARG A 1 233 ? 127.315 99.355  102.337 1.00 53.68  ? 233 ARG A HB2  1 
ATOM   3406 H HB3  . ARG A 1 233 ? 126.497 100.285 103.328 1.00 53.68  ? 233 ARG A HB3  1 
ATOM   3407 H HG2  . ARG A 1 233 ? 128.467 100.362 104.696 1.00 53.68  ? 233 ARG A HG2  1 
ATOM   3408 H HG3  . ARG A 1 233 ? 129.240 99.700  103.471 1.00 53.68  ? 233 ARG A HG3  1 
ATOM   3409 H HD2  . ARG A 1 233 ? 127.914 102.184 103.332 1.00 53.68  ? 233 ARG A HD2  1 
ATOM   3410 H HD3  . ARG A 1 233 ? 129.488 102.035 103.461 1.00 53.68  ? 233 ARG A HD3  1 
ATOM   3411 H HE   . ARG A 1 233 ? 128.046 101.505 101.212 1.00 53.68  ? 233 ARG A HE   1 
ATOM   3412 H HH11 . ARG A 1 233 ? 131.122 101.387 102.461 1.00 53.68  ? 233 ARG A HH11 1 
ATOM   3413 H HH12 . ARG A 1 233 ? 131.804 101.280 101.144 1.00 53.68  ? 233 ARG A HH12 1 
ATOM   3414 H HH21 . ARG A 1 233 ? 129.130 101.453 99.243  1.00 53.68  ? 233 ARG A HH21 1 
ATOM   3415 H HH22 . ARG A 1 233 ? 130.612 101.319 99.210  1.00 53.68  ? 233 ARG A HH22 1 
ATOM   3416 N N    . ARG A 1 234 ? 125.104 97.242  102.713 1.00 52.50  ? 234 ARG A N    1 
ATOM   3417 C CA   . ARG A 1 234 ? 123.737 96.913  102.323 1.00 52.50  ? 234 ARG A CA   1 
ATOM   3418 C C    . ARG A 1 234 ? 122.987 96.248  103.468 1.00 52.50  ? 234 ARG A C    1 
ATOM   3419 O O    . ARG A 1 234 ? 121.863 96.642  103.799 1.00 52.50  ? 234 ARG A O    1 
ATOM   3420 C CB   . ARG A 1 234 ? 123.735 96.011  101.085 1.00 52.50  ? 234 ARG A CB   1 
ATOM   3421 C CG   . ARG A 1 234 ? 124.651 94.798  101.174 1.00 52.50  ? 234 ARG A CG   1 
ATOM   3422 C CD   . ARG A 1 234 ? 124.094 93.607  100.416 1.00 52.50  ? 234 ARG A CD   1 
ATOM   3423 N NE   . ARG A 1 234 ? 124.877 92.403  100.664 1.00 52.50  ? 234 ARG A NE   1 
ATOM   3424 C CZ   . ARG A 1 234 ? 124.633 91.220  100.117 1.00 52.50  ? 234 ARG A CZ   1 
ATOM   3425 N NH1  . ARG A 1 234 ? 123.629 91.041  99.276  1.00 52.50  ? 234 ARG A NH1  1 
ATOM   3426 N NH2  . ARG A 1 234 ? 125.420 90.191  100.419 1.00 52.50  ? 234 ARG A NH2  1 
ATOM   3427 H H    . ARG A 1 234 ? 125.715 96.897  102.214 1.00 52.50  ? 234 ARG A H    1 
ATOM   3428 H HA   . ARG A 1 234 ? 123.269 97.732  102.097 1.00 52.50  ? 234 ARG A HA   1 
ATOM   3429 H HB2  . ARG A 1 234 ? 122.832 95.687  100.943 1.00 52.50  ? 234 ARG A HB2  1 
ATOM   3430 H HB3  . ARG A 1 234 ? 124.018 96.537  100.321 1.00 52.50  ? 234 ARG A HB3  1 
ATOM   3431 H HG2  . ARG A 1 234 ? 125.510 95.024  100.784 1.00 52.50  ? 234 ARG A HG2  1 
ATOM   3432 H HG3  . ARG A 1 234 ? 124.771 94.534  102.095 1.00 52.50  ? 234 ARG A HG3  1 
ATOM   3433 H HD2  . ARG A 1 234 ? 123.183 93.440  100.704 1.00 52.50  ? 234 ARG A HD2  1 
ATOM   3434 H HD3  . ARG A 1 234 ? 124.117 93.794  99.464  1.00 52.50  ? 234 ARG A HD3  1 
ATOM   3435 H HE   . ARG A 1 234 ? 125.601 92.487  101.122 1.00 52.50  ? 234 ARG A HE   1 
ATOM   3436 H HH11 . ARG A 1 234 ? 123.113 91.699  99.071  1.00 52.50  ? 234 ARG A HH11 1 
ATOM   3437 H HH12 . ARG A 1 234 ? 123.491 90.265  98.932  1.00 52.50  ? 234 ARG A HH12 1 
ATOM   3438 H HH21 . ARG A 1 234 ? 126.076 90.297  100.964 1.00 52.50  ? 234 ARG A HH21 1 
ATOM   3439 H HH22 . ARG A 1 234 ? 125.272 89.420  100.069 1.00 52.50  ? 234 ARG A HH22 1 
ATOM   3440 N N    . THR A 1 235 ? 123.592 95.237  104.090 1.00 50.35  ? 235 THR A N    1 
ATOM   3441 C CA   . THR A 1 235 ? 122.887 94.506  105.132 1.00 50.35  ? 235 THR A CA   1 
ATOM   3442 C C    . THR A 1 235 ? 122.560 95.421  106.301 1.00 50.35  ? 235 THR A C    1 
ATOM   3443 O O    . THR A 1 235 ? 121.428 95.435  106.792 1.00 50.35  ? 235 THR A O    1 
ATOM   3444 C CB   . THR A 1 235 ? 123.715 93.310  105.600 1.00 50.35  ? 235 THR A CB   1 
ATOM   3445 O OG1  . THR A 1 235 ? 124.927 93.772  106.205 1.00 50.35  ? 235 THR A OG1  1 
ATOM   3446 C CG2  . THR A 1 235 ? 124.046 92.405  104.427 1.00 50.35  ? 235 THR A CG2  1 
ATOM   3447 H H    . THR A 1 235 ? 124.395 94.970  103.945 1.00 50.35  ? 235 THR A H    1 
ATOM   3448 H HA   . THR A 1 235 ? 122.052 94.169  104.772 1.00 50.35  ? 235 THR A HA   1 
ATOM   3449 H HB   . THR A 1 235 ? 123.206 92.798  106.248 1.00 50.35  ? 235 THR A HB   1 
ATOM   3450 H HG1  . THR A 1 235 ? 125.357 93.122  106.519 1.00 50.35  ? 235 THR A HG1  1 
ATOM   3451 H HG21 . THR A 1 235 ? 124.391 91.557  104.750 1.00 50.35  ? 235 THR A HG21 1 
ATOM   3452 H HG22 . THR A 1 235 ? 123.248 92.241  103.901 1.00 50.35  ? 235 THR A HG22 1 
ATOM   3453 H HG23 . THR A 1 235 ? 124.715 92.823  103.863 1.00 50.35  ? 235 THR A HG23 1 
ATOM   3454 N N    . VAL A 1 236 ? 123.529 96.223  106.741 1.00 51.05  ? 236 VAL A N    1 
ATOM   3455 C CA   . VAL A 1 236 ? 123.296 97.083  107.897 1.00 51.05  ? 236 VAL A CA   1 
ATOM   3456 C C    . VAL A 1 236 ? 122.172 98.067  107.606 1.00 51.05  ? 236 VAL A C    1 
ATOM   3457 O O    . VAL A 1 236 ? 121.226 98.205  108.390 1.00 51.05  ? 236 VAL A O    1 
ATOM   3458 C CB   . VAL A 1 236 ? 124.590 97.807  108.301 1.00 51.05  ? 236 VAL A CB   1 
ATOM   3459 C CG1  . VAL A 1 236 ? 124.296 98.857  109.354 1.00 51.05  ? 236 VAL A CG1  1 
ATOM   3460 C CG2  . VAL A 1 236 ? 125.608 96.811  108.823 1.00 51.05  ? 236 VAL A CG2  1 
ATOM   3461 H H    . VAL A 1 236 ? 124.313 96.289  106.393 1.00 51.05  ? 236 VAL A H    1 
ATOM   3462 H HA   . VAL A 1 236 ? 123.019 96.531  108.645 1.00 51.05  ? 236 VAL A HA   1 
ATOM   3463 H HB   . VAL A 1 236 ? 124.967 98.250  107.525 1.00 51.05  ? 236 VAL A HB   1 
ATOM   3464 H HG11 . VAL A 1 236 ? 125.130 99.129  109.769 1.00 51.05  ? 236 VAL A HG11 1 
ATOM   3465 H HG12 . VAL A 1 236 ? 123.873 99.623  108.936 1.00 51.05  ? 236 VAL A HG12 1 
ATOM   3466 H HG13 . VAL A 1 236 ? 123.707 98.473  110.022 1.00 51.05  ? 236 VAL A HG13 1 
ATOM   3467 H HG21 . VAL A 1 236 ? 126.366 97.295  109.185 1.00 51.05  ? 236 VAL A HG21 1 
ATOM   3468 H HG22 . VAL A 1 236 ? 125.195 96.274  109.518 1.00 51.05  ? 236 VAL A HG22 1 
ATOM   3469 H HG23 . VAL A 1 236 ? 125.896 96.242  108.092 1.00 51.05  ? 236 VAL A HG23 1 
ATOM   3470 N N    . ALA A 1 237 ? 122.245 98.756  106.467 1.00 47.68  ? 237 ALA A N    1 
ATOM   3471 C CA   . ALA A 1 237 ? 121.239 99.771  106.165 1.00 47.68  ? 237 ALA A CA   1 
ATOM   3472 C C    . ALA A 1 237 ? 119.853 99.152  106.009 1.00 47.68  ? 237 ALA A C    1 
ATOM   3473 O O    . ALA A 1 237 ? 118.867 99.639  106.584 1.00 47.68  ? 237 ALA A O    1 
ATOM   3474 C CB   . ALA A 1 237 ? 121.632 100.533 104.902 1.00 47.68  ? 237 ALA A CB   1 
ATOM   3475 H H    . ALA A 1 237 ? 122.853 98.659  105.867 1.00 47.68  ? 237 ALA A H    1 
ATOM   3476 H HA   . ALA A 1 237 ? 121.201 100.404 106.899 1.00 47.68  ? 237 ALA A HA   1 
ATOM   3477 H HB1  . ALA A 1 237 ? 120.918 101.148 104.674 1.00 47.68  ? 237 ALA A HB1  1 
ATOM   3478 H HB2  . ALA A 1 237 ? 122.452 101.022 105.071 1.00 47.68  ? 237 ALA A HB2  1 
ATOM   3479 H HB3  . ALA A 1 237 ? 121.764 99.900  104.180 1.00 47.68  ? 237 ALA A HB3  1 
ATOM   3480 N N    . ILE A 1 238 ? 119.751 98.077  105.228 1.00 48.54  ? 238 ILE A N    1 
ATOM   3481 C CA   . ILE A 1 238 ? 118.440 97.505  104.956 1.00 48.54  ? 238 ILE A CA   1 
ATOM   3482 C C    . ILE A 1 238 ? 117.852 96.887  106.217 1.00 48.54  ? 238 ILE A C    1 
ATOM   3483 O O    . ILE A 1 238 ? 116.643 96.970  106.451 1.00 48.54  ? 238 ILE A O    1 
ATOM   3484 C CB   . ILE A 1 238 ? 118.530 96.489  103.806 1.00 48.54  ? 238 ILE A CB   1 
ATOM   3485 C CG1  . ILE A 1 238 ? 119.052 97.174  102.537 1.00 48.54  ? 238 ILE A CG1  1 
ATOM   3486 C CG2  . ILE A 1 238 ? 117.174 95.849  103.564 1.00 48.54  ? 238 ILE A CG2  1 
ATOM   3487 C CD1  . ILE A 1 238 ? 118.308 98.433  102.157 1.00 48.54  ? 238 ILE A CD1  1 
ATOM   3488 H H    . ILE A 1 238 ? 120.410 97.672  104.851 1.00 48.54  ? 238 ILE A H    1 
ATOM   3489 H HA   . ILE A 1 238 ? 117.840 98.217  104.688 1.00 48.54  ? 238 ILE A HA   1 
ATOM   3490 H HB   . ILE A 1 238 ? 119.157 95.793  104.057 1.00 48.54  ? 238 ILE A HB   1 
ATOM   3491 H HG12 . ILE A 1 238 ? 119.979 97.421  102.674 1.00 48.54  ? 238 ILE A HG12 1 
ATOM   3492 H HG13 . ILE A 1 238 ? 118.987 96.555  101.793 1.00 48.54  ? 238 ILE A HG13 1 
ATOM   3493 H HG21 . ILE A 1 238 ? 117.190 95.382  102.714 1.00 48.54  ? 238 ILE A HG21 1 
ATOM   3494 H HG22 . ILE A 1 238 ? 116.988 95.222  104.280 1.00 48.54  ? 238 ILE A HG22 1 
ATOM   3495 H HG23 . ILE A 1 238 ? 116.497 96.543  103.548 1.00 48.54  ? 238 ILE A HG23 1 
ATOM   3496 H HD11 . ILE A 1 238 ? 118.598 98.716  101.277 1.00 48.54  ? 238 ILE A HD11 1 
ATOM   3497 H HD12 . ILE A 1 238 ? 117.356 98.247  102.152 1.00 48.54  ? 238 ILE A HD12 1 
ATOM   3498 H HD13 . ILE A 1 238 ? 118.507 99.127  102.805 1.00 48.54  ? 238 ILE A HD13 1 
ATOM   3499 N N    . LEU A 1 239 ? 118.684 96.264  107.054 1.00 46.01  ? 239 LEU A N    1 
ATOM   3500 C CA   . LEU A 1 239 ? 118.173 95.719  108.303 1.00 46.01  ? 239 LEU A CA   1 
ATOM   3501 C C    . LEU A 1 239 ? 117.780 96.823  109.272 1.00 46.01  ? 239 LEU A C    1 
ATOM   3502 O O    . LEU A 1 239 ? 116.859 96.637  110.069 1.00 46.01  ? 239 LEU A O    1 
ATOM   3503 C CB   . LEU A 1 239 ? 119.208 94.791  108.932 1.00 46.01  ? 239 LEU A CB   1 
ATOM   3504 C CG   . LEU A 1 239 ? 119.204 93.353  108.412 1.00 46.01  ? 239 LEU A CG   1 
ATOM   3505 C CD1  . LEU A 1 239 ? 118.101 92.574  109.090 1.00 46.01  ? 239 LEU A CD1  1 
ATOM   3506 C CD2  . LEU A 1 239 ? 119.027 93.299  106.905 1.00 46.01  ? 239 LEU A CD2  1 
ATOM   3507 H H    . LEU A 1 239 ? 119.526 96.148  106.923 1.00 46.01  ? 239 LEU A H    1 
ATOM   3508 H HA   . LEU A 1 239 ? 117.377 95.197  108.117 1.00 46.01  ? 239 LEU A HA   1 
ATOM   3509 H HB2  . LEU A 1 239 ? 120.091 95.160  108.780 1.00 46.01  ? 239 LEU A HB2  1 
ATOM   3510 H HB3  . LEU A 1 239 ? 119.033 94.742  109.883 1.00 46.01  ? 239 LEU A HB3  1 
ATOM   3511 H HG   . LEU A 1 239 ? 120.051 92.933  108.630 1.00 46.01  ? 239 LEU A HG   1 
ATOM   3512 H HD11 . LEU A 1 239 ? 118.065 91.682  108.711 1.00 46.01  ? 239 LEU A HD11 1 
ATOM   3513 H HD12 . LEU A 1 239 ? 118.288 92.524  110.040 1.00 46.01  ? 239 LEU A HD12 1 
ATOM   3514 H HD13 . LEU A 1 239 ? 117.258 93.031  108.942 1.00 46.01  ? 239 LEU A HD13 1 
ATOM   3515 H HD21 . LEU A 1 239 ? 119.195 92.393  106.603 1.00 46.01  ? 239 LEU A HD21 1 
ATOM   3516 H HD22 . LEU A 1 239 ? 118.119 93.556  106.683 1.00 46.01  ? 239 LEU A HD22 1 
ATOM   3517 H HD23 . LEU A 1 239 ? 119.656 93.907  106.487 1.00 46.01  ? 239 LEU A HD23 1 
ATOM   3518 N N    . TYR A 1 240 ? 118.445 97.976  109.218 1.00 45.64  ? 240 TYR A N    1 
ATOM   3519 C CA   . TYR A 1 240 ? 117.992 99.122  110.000 1.00 45.64  ? 240 TYR A CA   1 
ATOM   3520 C C    . TYR A 1 240 ? 116.590 99.542  109.575 1.00 45.64  ? 240 TYR A C    1 
ATOM   3521 O O    . TYR A 1 240 ? 115.696 99.733  110.412 1.00 45.64  ? 240 TYR A O    1 
ATOM   3522 C CB   . TYR A 1 240 ? 118.979 100.272 109.821 1.00 45.64  ? 240 TYR A CB   1 
ATOM   3523 C CG   . TYR A 1 240 ? 118.938 101.331 110.889 1.00 45.64  ? 240 TYR A CG   1 
ATOM   3524 C CD1  . TYR A 1 240 ? 119.554 101.133 112.111 1.00 45.64  ? 240 TYR A CD1  1 
ATOM   3525 C CD2  . TYR A 1 240 ? 118.314 102.543 110.662 1.00 45.64  ? 240 TYR A CD2  1 
ATOM   3526 C CE1  . TYR A 1 240 ? 119.535 102.104 113.080 1.00 45.64  ? 240 TYR A CE1  1 
ATOM   3527 C CE2  . TYR A 1 240 ? 118.288 103.519 111.626 1.00 45.64  ? 240 TYR A CE2  1 
ATOM   3528 C CZ   . TYR A 1 240 ? 118.901 103.295 112.833 1.00 45.64  ? 240 TYR A CZ   1 
ATOM   3529 O OH   . TYR A 1 240 ? 118.881 104.267 113.804 1.00 45.64  ? 240 TYR A OH   1 
ATOM   3530 H H    . TYR A 1 240 ? 119.151 98.118  108.748 1.00 45.64  ? 240 TYR A H    1 
ATOM   3531 H HA   . TYR A 1 240 ? 117.967 98.883  110.940 1.00 45.64  ? 240 TYR A HA   1 
ATOM   3532 H HB2  . TYR A 1 240 ? 119.878 99.908  109.807 1.00 45.64  ? 240 TYR A HB2  1 
ATOM   3533 H HB3  . TYR A 1 240 ? 118.793 100.707 108.974 1.00 45.64  ? 240 TYR A HB3  1 
ATOM   3534 H HD1  . TYR A 1 240 ? 119.985 100.327 112.281 1.00 45.64  ? 240 TYR A HD1  1 
ATOM   3535 H HD2  . TYR A 1 240 ? 117.899 102.697 109.844 1.00 45.64  ? 240 TYR A HD2  1 
ATOM   3536 H HE1  . TYR A 1 240 ? 119.948 101.956 113.900 1.00 45.64  ? 240 TYR A HE1  1 
ATOM   3537 H HE2  . TYR A 1 240 ? 117.860 104.327 111.461 1.00 45.64  ? 240 TYR A HE2  1 
ATOM   3538 H HH   . TYR A 1 240 ? 118.468 104.944 113.526 1.00 45.64  ? 240 TYR A HH   1 
ATOM   3539 N N    . GLN A 1 241 ? 116.374 99.670  108.266 1.00 45.79  ? 241 GLN A N    1 
ATOM   3540 C CA   . GLN A 1 241 ? 115.042 100.025 107.784 1.00 45.79  ? 241 GLN A CA   1 
ATOM   3541 C C    . GLN A 1 241 ? 114.011 98.967  108.177 1.00 45.79  ? 241 GLN A C    1 
ATOM   3542 O O    . GLN A 1 241 ? 112.883 99.295  108.570 1.00 45.79  ? 241 GLN A O    1 
ATOM   3543 C CB   . GLN A 1 241 ? 115.069 100.215 106.269 1.00 45.79  ? 241 GLN A CB   1 
ATOM   3544 C CG   . GLN A 1 241 ? 115.946 101.363 105.807 1.00 45.79  ? 241 GLN A CG   1 
ATOM   3545 C CD   . GLN A 1 241 ? 115.341 102.713 106.115 1.00 45.79  ? 241 GLN A CD   1 
ATOM   3546 O OE1  . GLN A 1 241 ? 114.365 102.812 106.855 1.00 45.79  ? 241 GLN A OE1  1 
ATOM   3547 N NE2  . GLN A 1 241 ? 115.916 103.763 105.544 1.00 45.79  ? 241 GLN A NE2  1 
ATOM   3548 H H    . GLN A 1 241 ? 116.968 99.567  107.652 1.00 45.79  ? 241 GLN A H    1 
ATOM   3549 H HA   . GLN A 1 241 ? 114.777 100.866 108.188 1.00 45.79  ? 241 GLN A HA   1 
ATOM   3550 H HB2  . GLN A 1 241 ? 115.404 99.403  105.856 1.00 45.79  ? 241 GLN A HB2  1 
ATOM   3551 H HB3  . GLN A 1 241 ? 114.166 100.392 105.960 1.00 45.79  ? 241 GLN A HB3  1 
ATOM   3552 H HG2  . GLN A 1 241 ? 116.802 101.310 106.258 1.00 45.79  ? 241 GLN A HG2  1 
ATOM   3553 H HG3  . GLN A 1 241 ? 116.074 101.302 104.847 1.00 45.79  ? 241 GLN A HG3  1 
ATOM   3554 H HE21 . GLN A 1 241 ? 116.597 103.653 105.030 1.00 45.79  ? 241 GLN A HE21 1 
ATOM   3555 H HE22 . GLN A 1 241 ? 115.608 104.553 105.687 1.00 45.79  ? 241 GLN A HE22 1 
ATOM   3556 N N    . MET A 1 242 ? 114.379 97.689  108.079 1.00 45.51  ? 242 MET A N    1 
ATOM   3557 C CA   . MET A 1 242 ? 113.448 96.625  108.441 1.00 45.51  ? 242 MET A CA   1 
ATOM   3558 C C    . MET A 1 242 ? 113.145 96.627  109.935 1.00 45.51  ? 242 MET A C    1 
ATOM   3559 O O    . MET A 1 242 ? 112.020 96.312  110.338 1.00 45.51  ? 242 MET A O    1 
ATOM   3560 C CB   . MET A 1 242 ? 114.007 95.271  108.012 1.00 45.51  ? 242 MET A CB   1 
ATOM   3561 C CG   . MET A 1 242 ? 113.001 94.152  108.115 1.00 45.51  ? 242 MET A CG   1 
ATOM   3562 S SD   . MET A 1 242 ? 113.502 92.662  107.239 1.00 45.51  ? 242 MET A SD   1 
ATOM   3563 C CE   . MET A 1 242 ? 113.748 91.535  108.608 1.00 45.51  ? 242 MET A CE   1 
ATOM   3564 H H    . MET A 1 242 ? 115.145 97.418  107.797 1.00 45.51  ? 242 MET A H    1 
ATOM   3565 H HA   . MET A 1 242 ? 112.619 96.763  107.958 1.00 45.51  ? 242 MET A HA   1 
ATOM   3566 H HB2  . MET A 1 242 ? 114.299 95.328  107.088 1.00 45.51  ? 242 MET A HB2  1 
ATOM   3567 H HB3  . MET A 1 242 ? 114.759 95.050  108.584 1.00 45.51  ? 242 MET A HB3  1 
ATOM   3568 H HG2  . MET A 1 242 ? 112.887 93.922  109.050 1.00 45.51  ? 242 MET A HG2  1 
ATOM   3569 H HG3  . MET A 1 242 ? 112.158 94.455  107.743 1.00 45.51  ? 242 MET A HG3  1 
ATOM   3570 H HE1  . MET A 1 242 ? 114.044 90.679  108.261 1.00 45.51  ? 242 MET A HE1  1 
ATOM   3571 H HE2  . MET A 1 242 ? 114.421 91.903  109.201 1.00 45.51  ? 242 MET A HE2  1 
ATOM   3572 H HE3  . MET A 1 242 ? 112.910 91.427  109.085 1.00 45.51  ? 242 MET A HE3  1 
ATOM   3573 N N    . ALA A 1 243 ? 114.126 96.973  110.768 1.00 43.44  ? 243 ALA A N    1 
ATOM   3574 C CA   . ALA A 1 243 ? 113.853 97.172  112.186 1.00 43.44  ? 243 ALA A CA   1 
ATOM   3575 C C    . ALA A 1 243 ? 112.863 98.302  112.390 1.00 43.44  ? 243 ALA A C    1 
ATOM   3576 O O    . ALA A 1 243 ? 111.988 98.223  113.258 1.00 43.44  ? 243 ALA A O    1 
ATOM   3577 C CB   . ALA A 1 243 ? 115.143 97.476  112.936 1.00 43.44  ? 243 ALA A CB   1 
ATOM   3578 H H    . ALA A 1 243 ? 114.948 97.087  110.543 1.00 43.44  ? 243 ALA A H    1 
ATOM   3579 H HA   . ALA A 1 243 ? 113.471 96.360  112.555 1.00 43.44  ? 243 ALA A HA   1 
ATOM   3580 H HB1  . ALA A 1 243 ? 114.915 97.710  113.849 1.00 43.44  ? 243 ALA A HB1  1 
ATOM   3581 H HB2  . ALA A 1 243 ? 115.710 96.692  112.920 1.00 43.44  ? 243 ALA A HB2  1 
ATOM   3582 H HB3  . ALA A 1 243 ? 115.584 98.228  112.506 1.00 43.44  ? 243 ALA A HB3  1 
ATOM   3583 N N    . PHE A 1 244 ? 112.997 99.376  111.615 1.00 39.50  ? 244 PHE A N    1 
ATOM   3584 C CA   . PHE A 1 244 ? 112.010 100.445 111.700 1.00 39.50  ? 244 PHE A CA   1 
ATOM   3585 C C    . PHE A 1 244 ? 110.616 99.922  111.370 1.00 39.50  ? 244 PHE A C    1 
ATOM   3586 O O    . PHE A 1 244 ? 109.639 100.256 112.051 1.00 39.50  ? 244 PHE A O    1 
ATOM   3587 C CB   . PHE A 1 244 ? 112.393 101.590 110.767 1.00 39.50  ? 244 PHE A CB   1 
ATOM   3588 C CG   . PHE A 1 244 ? 111.303 102.592 110.569 1.00 39.50  ? 244 PHE A CG   1 
ATOM   3589 C CD1  . PHE A 1 244 ? 111.041 103.539 111.533 1.00 39.50  ? 244 PHE A CD1  1 
ATOM   3590 C CD2  . PHE A 1 244 ? 110.541 102.588 109.421 1.00 39.50  ? 244 PHE A CD2  1 
ATOM   3591 C CE1  . PHE A 1 244 ? 110.042 104.461 111.358 1.00 39.50  ? 244 PHE A CE1  1 
ATOM   3592 C CE2  . PHE A 1 244 ? 109.542 103.509 109.240 1.00 39.50  ? 244 PHE A CE2  1 
ATOM   3593 C CZ   . PHE A 1 244 ? 109.291 104.446 110.210 1.00 39.50  ? 244 PHE A CZ   1 
ATOM   3594 H H    . PHE A 1 244 ? 113.632 99.508  111.048 1.00 39.50  ? 244 PHE A H    1 
ATOM   3595 H HA   . PHE A 1 244 ? 111.998 100.790 112.606 1.00 39.50  ? 244 PHE A HA   1 
ATOM   3596 H HB2  . PHE A 1 244 ? 113.155 102.057 111.144 1.00 39.50  ? 244 PHE A HB2  1 
ATOM   3597 H HB3  . PHE A 1 244 ? 112.629 101.231 109.898 1.00 39.50  ? 244 PHE A HB3  1 
ATOM   3598 H HD1  . PHE A 1 244 ? 111.548 103.552 112.313 1.00 39.50  ? 244 PHE A HD1  1 
ATOM   3599 H HD2  . PHE A 1 244 ? 110.708 101.954 108.760 1.00 39.50  ? 244 PHE A HD2  1 
ATOM   3600 H HE1  . PHE A 1 244 ? 109.874 105.095 112.017 1.00 39.50  ? 244 PHE A HE1  1 
ATOM   3601 H HE2  . PHE A 1 244 ? 109.033 103.497 108.462 1.00 39.50  ? 244 PHE A HE2  1 
ATOM   3602 H HZ   . PHE A 1 244 ? 108.613 105.071 110.090 1.00 39.50  ? 244 PHE A HZ   1 
ATOM   3603 N N    . THR A 1 245 ? 110.507 99.090  110.333 1.00 41.46  ? 245 THR A N    1 
ATOM   3604 C CA   . THR A 1 245 ? 109.202 98.535  109.970 1.00 41.46  ? 245 THR A CA   1 
ATOM   3605 C C    . THR A 1 245 ? 108.642 97.654  111.084 1.00 41.46  ? 245 THR A C    1 
ATOM   3606 O O    . THR A 1 245 ? 107.442 97.706  111.392 1.00 41.46  ? 245 THR A O    1 
ATOM   3607 C CB   . THR A 1 245 ? 109.307 97.741  108.669 1.00 41.46  ? 245 THR A CB   1 
ATOM   3608 O OG1  . THR A 1 245 ? 109.730 98.608  107.610 1.00 41.46  ? 245 THR A OG1  1 
ATOM   3609 C CG2  . THR A 1 245 ? 107.965 97.124  108.302 1.00 41.46  ? 245 THR A CG2  1 
ATOM   3610 H H    . THR A 1 245 ? 111.159 98.833  109.835 1.00 41.46  ? 245 THR A H    1 
ATOM   3611 H HA   . THR A 1 245 ? 108.581 99.267  109.825 1.00 41.46  ? 245 THR A HA   1 
ATOM   3612 H HB   . THR A 1 245 ? 109.953 97.025  108.778 1.00 41.46  ? 245 THR A HB   1 
ATOM   3613 H HG1  . THR A 1 245 ? 109.218 99.272  107.560 1.00 41.46  ? 245 THR A HG1  1 
ATOM   3614 H HG21 . THR A 1 245 ? 108.014 96.743  107.410 1.00 41.46  ? 245 THR A HG21 1 
ATOM   3615 H HG22 . THR A 1 245 ? 107.729 96.420  108.926 1.00 41.46  ? 245 THR A HG22 1 
ATOM   3616 H HG23 . THR A 1 245 ? 107.272 97.803  108.311 1.00 41.46  ? 245 THR A HG23 1 
ATOM   3617 N N    . VAL A 1 246 ? 109.492 96.823  111.688 1.00 41.72  ? 246 VAL A N    1 
ATOM   3618 C CA   . VAL A 1 246 ? 109.047 95.986  112.800 1.00 41.72  ? 246 VAL A CA   1 
ATOM   3619 C C    . VAL A 1 246 ? 108.574 96.855  113.955 1.00 41.72  ? 246 VAL A C    1 
ATOM   3620 O O    . VAL A 1 246 ? 107.584 96.541  114.628 1.00 41.72  ? 246 VAL A O    1 
ATOM   3621 C CB   . VAL A 1 246 ? 110.173 95.031  113.237 1.00 41.72  ? 246 VAL A CB   1 
ATOM   3622 C CG1  . VAL A 1 246 ? 109.823 94.349  114.551 1.00 41.72  ? 246 VAL A CG1  1 
ATOM   3623 C CG2  . VAL A 1 246 ? 110.439 93.997  112.160 1.00 41.72  ? 246 VAL A CG2  1 
ATOM   3624 H H    . VAL A 1 246 ? 110.321 96.728  111.479 1.00 41.72  ? 246 VAL A H    1 
ATOM   3625 H HA   . VAL A 1 246 ? 108.295 95.447  112.507 1.00 41.72  ? 246 VAL A HA   1 
ATOM   3626 H HB   . VAL A 1 246 ? 110.985 95.544  113.371 1.00 41.72  ? 246 VAL A HB   1 
ATOM   3627 H HG11 . VAL A 1 246 ? 110.395 93.572  114.658 1.00 41.72  ? 246 VAL A HG11 1 
ATOM   3628 H HG12 . VAL A 1 246 ? 109.972 94.967  115.284 1.00 41.72  ? 246 VAL A HG12 1 
ATOM   3629 H HG13 . VAL A 1 246 ? 108.894 94.071  114.530 1.00 41.72  ? 246 VAL A HG13 1 
ATOM   3630 H HG21 . VAL A 1 246 ? 111.242 93.504  112.392 1.00 41.72  ? 246 VAL A HG21 1 
ATOM   3631 H HG22 . VAL A 1 246 ? 109.683 93.392  112.110 1.00 41.72  ? 246 VAL A HG22 1 
ATOM   3632 H HG23 . VAL A 1 246 ? 110.564 94.448  111.310 1.00 41.72  ? 246 VAL A HG23 1 
ATOM   3633 N N    . GLY A 1 247 ? 109.280 97.954  114.213 1.00 41.29  ? 247 GLY A N    1 
ATOM   3634 C CA   . GLY A 1 247 ? 108.830 98.881  115.233 1.00 41.29  ? 247 GLY A CA   1 
ATOM   3635 C C    . GLY A 1 247 ? 107.468 99.461  114.913 1.00 41.29  ? 247 GLY A C    1 
ATOM   3636 O O    . GLY A 1 247 ? 106.638 99.649  115.802 1.00 41.29  ? 247 GLY A O    1 
ATOM   3637 H H    . GLY A 1 247 ? 110.009 98.180  113.815 1.00 41.29  ? 247 GLY A H    1 
ATOM   3638 H HA2  . GLY A 1 247 ? 108.779 98.427  116.089 1.00 41.29  ? 247 GLY A HA2  1 
ATOM   3639 H HA3  . GLY A 1 247 ? 109.463 99.612  115.310 1.00 41.29  ? 247 GLY A HA3  1 
ATOM   3640 N N    . LEU A 1 248 ? 107.218 99.749  113.636 1.00 39.93  ? 248 LEU A N    1 
ATOM   3641 C CA   . LEU A 1 248 ? 105.908 100.262 113.243 1.00 39.93  ? 248 LEU A CA   1 
ATOM   3642 C C    . LEU A 1 248 ? 104.812 99.236  113.513 1.00 39.93  ? 248 LEU A C    1 
ATOM   3643 O O    . LEU A 1 248 ? 103.738 99.576  114.032 1.00 39.93  ? 248 LEU A O    1 
ATOM   3644 C CB   . LEU A 1 248 ? 105.925 100.648 111.765 1.00 39.93  ? 248 LEU A CB   1 
ATOM   3645 C CG   . LEU A 1 248 ? 104.947 101.739 111.340 1.00 39.93  ? 248 LEU A CG   1 
ATOM   3646 C CD1  . LEU A 1 248 ? 105.335 103.068 111.961 1.00 39.93  ? 248 LEU A CD1  1 
ATOM   3647 C CD2  . LEU A 1 248 ? 104.912 101.845 109.831 1.00 39.93  ? 248 LEU A CD2  1 
ATOM   3648 H H    . LEU A 1 248 ? 107.780 99.662  112.991 1.00 39.93  ? 248 LEU A H    1 
ATOM   3649 H HA   . LEU A 1 248 ? 105.713 101.056 113.763 1.00 39.93  ? 248 LEU A HA   1 
ATOM   3650 H HB2  . LEU A 1 248 ? 106.816 100.961 111.542 1.00 39.93  ? 248 LEU A HB2  1 
ATOM   3651 H HB3  . LEU A 1 248 ? 105.722 99.859  111.239 1.00 39.93  ? 248 LEU A HB3  1 
ATOM   3652 H HG   . LEU A 1 248 ? 104.057 101.508 111.649 1.00 39.93  ? 248 LEU A HG   1 
ATOM   3653 H HD11 . LEU A 1 248 ? 104.797 103.771 111.564 1.00 39.93  ? 248 LEU A HD11 1 
ATOM   3654 H HD12 . LEU A 1 248 ? 105.176 103.031 112.917 1.00 39.93  ? 248 LEU A HD12 1 
ATOM   3655 H HD13 . LEU A 1 248 ? 106.275 103.233 111.787 1.00 39.93  ? 248 LEU A HD13 1 
ATOM   3656 H HD21 . LEU A 1 248 ? 104.317 102.568 109.578 1.00 39.93  ? 248 LEU A HD21 1 
ATOM   3657 H HD22 . LEU A 1 248 ? 105.808 102.025 109.508 1.00 39.93  ? 248 LEU A HD22 1 
ATOM   3658 H HD23 . LEU A 1 248 ? 104.590 101.006 109.464 1.00 39.93  ? 248 LEU A HD23 1 
ATOM   3659 N N    . VAL A 1 249 ? 105.063 97.972  113.170 1.00 39.14  ? 249 VAL A N    1 
ATOM   3660 C CA   . VAL A 1 249 ? 104.066 96.928  113.417 1.00 39.14  ? 249 VAL A CA   1 
ATOM   3661 C C    . VAL A 1 249 ? 103.807 96.788  114.913 1.00 39.14  ? 249 VAL A C    1 
ATOM   3662 O O    . VAL A 1 249 ? 102.657 96.669  115.359 1.00 39.14  ? 249 VAL A O    1 
ATOM   3663 C CB   . VAL A 1 249 ? 104.513 95.593  112.797 1.00 39.14  ? 249 VAL A CB   1 
ATOM   3664 C CG1  . VAL A 1 249 ? 103.651 94.454  113.313 1.00 39.14  ? 249 VAL A CG1  1 
ATOM   3665 C CG2  . VAL A 1 249 ? 104.439 95.663  111.285 1.00 39.14  ? 249 VAL A CG2  1 
ATOM   3666 H H    . VAL A 1 249 ? 105.789 97.696  112.800 1.00 39.14  ? 249 VAL A H    1 
ATOM   3667 H HA   . VAL A 1 249 ? 103.232 97.187  112.995 1.00 39.14  ? 249 VAL A HA   1 
ATOM   3668 H HB   . VAL A 1 249 ? 105.432 95.415  113.049 1.00 39.14  ? 249 VAL A HB   1 
ATOM   3669 H HG11 . VAL A 1 249 ? 103.757 93.690  112.724 1.00 39.14  ? 249 VAL A HG11 1 
ATOM   3670 H HG12 . VAL A 1 249 ? 103.934 94.217  114.210 1.00 39.14  ? 249 VAL A HG12 1 
ATOM   3671 H HG13 . VAL A 1 249 ? 102.722 94.736  113.319 1.00 39.14  ? 249 VAL A HG13 1 
ATOM   3672 H HG21 . VAL A 1 249 ? 104.735 94.816  110.916 1.00 39.14  ? 249 VAL A HG21 1 
ATOM   3673 H HG22 . VAL A 1 249 ? 103.522 95.836  111.020 1.00 39.14  ? 249 VAL A HG22 1 
ATOM   3674 H HG23 . VAL A 1 249 ? 105.015 96.378  110.973 1.00 39.14  ? 249 VAL A HG23 1 
ATOM   3675 N N    . LEU A 1 250 ? 104.878 96.784  115.710 1.00 40.87  ? 250 LEU A N    1 
ATOM   3676 C CA   . LEU A 1 250 ? 104.714 96.692  117.156 1.00 40.87  ? 250 LEU A CA   1 
ATOM   3677 C C    . LEU A 1 250 ? 103.941 97.884  117.701 1.00 40.87  ? 250 LEU A C    1 
ATOM   3678 O O    . LEU A 1 250 ? 103.145 97.735  118.637 1.00 40.87  ? 250 LEU A O    1 
ATOM   3679 C CB   . LEU A 1 250 ? 106.078 96.596  117.835 1.00 40.87  ? 250 LEU A CB   1 
ATOM   3680 C CG   . LEU A 1 250 ? 106.028 96.360  119.345 1.00 40.87  ? 250 LEU A CG   1 
ATOM   3681 C CD1  . LEU A 1 250 ? 105.644 94.921  119.643 1.00 40.87  ? 250 LEU A CD1  1 
ATOM   3682 C CD2  . LEU A 1 250 ? 107.354 96.718  119.996 1.00 40.87  ? 250 LEU A CD2  1 
ATOM   3683 H H    . LEU A 1 250 ? 105.693 96.831  115.442 1.00 40.87  ? 250 LEU A H    1 
ATOM   3684 H HA   . LEU A 1 250 ? 104.214 95.888  117.366 1.00 40.87  ? 250 LEU A HA   1 
ATOM   3685 H HB2  . LEU A 1 250 ? 106.570 95.859  117.440 1.00 40.87  ? 250 LEU A HB2  1 
ATOM   3686 H HB3  . LEU A 1 250 ? 106.558 97.425  117.685 1.00 40.87  ? 250 LEU A HB3  1 
ATOM   3687 H HG   . LEU A 1 250 ? 105.348 96.933  119.733 1.00 40.87  ? 250 LEU A HG   1 
ATOM   3688 H HD11 . LEU A 1 250 ? 105.591 94.803  120.605 1.00 40.87  ? 250 LEU A HD11 1 
ATOM   3689 H HD12 . LEU A 1 250 ? 104.784 94.731  119.238 1.00 40.87  ? 250 LEU A HD12 1 
ATOM   3690 H HD13 . LEU A 1 250 ? 106.321 94.332  119.275 1.00 40.87  ? 250 LEU A HD13 1 
ATOM   3691 H HD21 . LEU A 1 250 ? 107.289 96.557  120.951 1.00 40.87  ? 250 LEU A HD21 1 
ATOM   3692 H HD22 . LEU A 1 250 ? 108.054 96.166  119.614 1.00 40.87  ? 250 LEU A HD22 1 
ATOM   3693 H HD23 . LEU A 1 250 ? 107.543 97.655  119.831 1.00 40.87  ? 250 LEU A HD23 1 
ATOM   3694 N N    . LEU A 1 251 ? 104.170 99.074  117.143 1.00 41.16  ? 251 LEU A N    1 
ATOM   3695 C CA   . LEU A 1 251 ? 103.410 100.241 117.569 1.00 41.16  ? 251 LEU A CA   1 
ATOM   3696 C C    . LEU A 1 251 ? 101.932 100.056 117.274 1.00 41.16  ? 251 LEU A C    1 
ATOM   3697 O O    . LEU A 1 251 ? 101.084 100.396 118.101 1.00 41.16  ? 251 LEU A O    1 
ATOM   3698 C CB   . LEU A 1 251 ? 103.933 101.501 116.884 1.00 41.16  ? 251 LEU A CB   1 
ATOM   3699 C CG   . LEU A 1 251 ? 103.310 102.814 117.368 1.00 41.16  ? 251 LEU A CG   1 
ATOM   3700 C CD1  . LEU A 1 251 ? 104.217 103.970 117.028 1.00 41.16  ? 251 LEU A CD1  1 
ATOM   3701 C CD2  . LEU A 1 251 ? 101.927 103.055 116.776 1.00 41.16  ? 251 LEU A CD2  1 
ATOM   3702 H H    . LEU A 1 251 ? 104.752 99.228  116.529 1.00 41.16  ? 251 LEU A H    1 
ATOM   3703 H HA   . LEU A 1 251 ? 103.519 100.358 118.524 1.00 41.16  ? 251 LEU A HA   1 
ATOM   3704 H HB2  . LEU A 1 251 ? 104.889 101.558 117.038 1.00 41.16  ? 251 LEU A HB2  1 
ATOM   3705 H HB3  . LEU A 1 251 ? 103.763 101.427 115.932 1.00 41.16  ? 251 LEU A HB3  1 
ATOM   3706 H HG   . LEU A 1 251 ? 103.219 102.781 118.333 1.00 41.16  ? 251 LEU A HG   1 
ATOM   3707 H HD11 . LEU A 1 251 ? 103.805 104.784 117.352 1.00 41.16  ? 251 LEU A HD11 1 
ATOM   3708 H HD12 . LEU A 1 251 ? 105.077 103.837 117.456 1.00 41.16  ? 251 LEU A HD12 1 
ATOM   3709 H HD13 . LEU A 1 251 ? 104.329 104.014 116.065 1.00 41.16  ? 251 LEU A HD13 1 
ATOM   3710 H HD21 . LEU A 1 251 ? 101.783 104.011 116.691 1.00 41.16  ? 251 LEU A HD21 1 
ATOM   3711 H HD22 . LEU A 1 251 ? 101.876 102.636 115.903 1.00 41.16  ? 251 LEU A HD22 1 
ATOM   3712 H HD23 . LEU A 1 251 ? 101.258 102.674 117.366 1.00 41.16  ? 251 LEU A HD23 1 
ATOM   3713 N N    . SER A 1 252 ? 101.601 99.530  116.095 1.00 40.61  ? 252 SER A N    1 
ATOM   3714 C CA   . SER A 1 252 ? 100.194 99.279  115.793 1.00 40.61  ? 252 SER A CA   1 
ATOM   3715 C C    . SER A 1 252 ? 99.591  98.308  116.798 1.00 40.61  ? 252 SER A C    1 
ATOM   3716 O O    . SER A 1 252 ? 98.481  98.526  117.310 1.00 40.61  ? 252 SER A O    1 
ATOM   3717 C CB   . SER A 1 252 ? 100.048 98.725  114.380 1.00 40.61  ? 252 SER A CB   1 
ATOM   3718 O OG   . SER A 1 252 ? 100.363 97.346  114.359 1.00 40.61  ? 252 SER A OG   1 
ATOM   3719 H H    . SER A 1 252 ? 102.153 99.315  115.471 1.00 40.61  ? 252 SER A H    1 
ATOM   3720 H HA   . SER A 1 252 ? 99.702  100.113 115.844 1.00 40.61  ? 252 SER A HA   1 
ATOM   3721 H HB2  . SER A 1 252 ? 99.132  98.846  114.084 1.00 40.61  ? 252 SER A HB2  1 
ATOM   3722 H HB3  . SER A 1 252 ? 100.654 99.198  113.789 1.00 40.61  ? 252 SER A HB3  1 
ATOM   3723 H HG   . SER A 1 252 ? 101.145 97.226  114.641 1.00 40.61  ? 252 SER A HG   1 
ATOM   3724 N N    . GLY A 1 253 ? 100.313 97.229  117.095 1.00 40.58  ? 253 GLY A N    1 
ATOM   3725 C CA   . GLY A 1 253 ? 99.807  96.268  118.060 1.00 40.58  ? 253 GLY A CA   1 
ATOM   3726 C C    . GLY A 1 253 ? 99.537  96.900  119.412 1.00 40.58  ? 253 GLY A C    1 
ATOM   3727 O O    . GLY A 1 253 ? 98.443  96.774  119.968 1.00 40.58  ? 253 GLY A O    1 
ATOM   3728 H H    . GLY A 1 253 ? 101.079 97.036  116.757 1.00 40.58  ? 253 GLY A H    1 
ATOM   3729 H HA2  . GLY A 1 253 ? 98.981  95.881  117.730 1.00 40.58  ? 253 GLY A HA2  1 
ATOM   3730 H HA3  . GLY A 1 253 ? 100.456 95.557  118.178 1.00 40.58  ? 253 GLY A HA3  1 
ATOM   3731 N N    . VAL A 1 254 ? 100.528 97.611  119.953 1.00 42.11  ? 254 VAL A N    1 
ATOM   3732 C CA   . VAL A 1 254 ? 100.357 98.206  121.275 1.00 42.11  ? 254 VAL A CA   1 
ATOM   3733 C C    . VAL A 1 254 ? 99.281  99.282  121.244 1.00 42.11  ? 254 VAL A C    1 
ATOM   3734 O O    . VAL A 1 254 ? 98.585  99.502  122.242 1.00 42.11  ? 254 VAL A O    1 
ATOM   3735 C CB   . VAL A 1 254 ? 101.694 98.762  121.802 1.00 42.11  ? 254 VAL A CB   1 
ATOM   3736 C CG1  . VAL A 1 254 ? 102.167 99.917  120.948 1.00 42.11  ? 254 VAL A CG1  1 
ATOM   3737 C CG2  . VAL A 1 254 ? 101.551 99.194  123.250 1.00 42.11  ? 254 VAL A CG2  1 
ATOM   3738 H H    . VAL A 1 254 ? 101.291 97.761  119.584 1.00 42.11  ? 254 VAL A H    1 
ATOM   3739 H HA   . VAL A 1 254 ? 100.063 97.516  121.890 1.00 42.11  ? 254 VAL A HA   1 
ATOM   3740 H HB   . VAL A 1 254 ? 102.366 98.064  121.761 1.00 42.11  ? 254 VAL A HB   1 
ATOM   3741 H HG11 . VAL A 1 254 ? 103.063 100.166 121.223 1.00 42.11  ? 254 VAL A HG11 1 
ATOM   3742 H HG12 . VAL A 1 254 ? 102.173 99.632  120.024 1.00 42.11  ? 254 VAL A HG12 1 
ATOM   3743 H HG13 . VAL A 1 254 ? 101.565 100.669 121.061 1.00 42.11  ? 254 VAL A HG13 1 
ATOM   3744 H HG21 . VAL A 1 254 ? 102.420 99.463  123.585 1.00 42.11  ? 254 VAL A HG21 1 
ATOM   3745 H HG22 . VAL A 1 254 ? 100.933 99.940  123.299 1.00 42.11  ? 254 VAL A HG22 1 
ATOM   3746 H HG23 . VAL A 1 254 ? 101.212 98.448  123.768 1.00 42.11  ? 254 VAL A HG23 1 
ATOM   3747 N N    . ALA A 1 255 ? 99.121  99.970  120.112 1.00 42.92  ? 255 ALA A N    1 
ATOM   3748 C CA   . ALA A 1 255 ? 98.066  100.969 120.000 1.00 42.92  ? 255 ALA A CA   1 
ATOM   3749 C C    . ALA A 1 255 ? 96.700  100.319 120.136 1.00 42.92  ? 255 ALA A C    1 
ATOM   3750 O O    . ALA A 1 255 ? 95.821  100.838 120.833 1.00 42.92  ? 255 ALA A O    1 
ATOM   3751 C CB   . ALA A 1 255 ? 98.180  101.710 118.668 1.00 42.92  ? 255 ALA A CB   1 
ATOM   3752 H H    . ALA A 1 255 ? 99.602  99.877  119.405 1.00 42.92  ? 255 ALA A H    1 
ATOM   3753 H HA   . ALA A 1 255 ? 98.165  101.617 120.715 1.00 42.92  ? 255 ALA A HA   1 
ATOM   3754 H HB1  . ALA A 1 255 ? 97.467  102.366 118.610 1.00 42.92  ? 255 ALA A HB1  1 
ATOM   3755 H HB2  . ALA A 1 255 ? 99.042  102.152 118.626 1.00 42.92  ? 255 ALA A HB2  1 
ATOM   3756 H HB3  . ALA A 1 255 ? 98.100  101.070 117.944 1.00 42.92  ? 255 ALA A HB3  1 
ATOM   3757 N N    . TYR A 1 256 ? 96.502  99.177  119.479 1.00 42.78  ? 256 TYR A N    1 
ATOM   3758 C CA   . TYR A 1 256 ? 95.261  98.442  119.700 1.00 42.78  ? 256 TYR A CA   1 
ATOM   3759 C C    . TYR A 1 256 ? 95.173  97.924  121.128 1.00 42.78  ? 256 TYR A C    1 
ATOM   3760 O O    . TYR A 1 256 ? 94.070  97.737  121.653 1.00 42.78  ? 256 TYR A O    1 
ATOM   3761 C CB   . TYR A 1 256 ? 95.134  97.281  118.719 1.00 42.78  ? 256 TYR A CB   1 
ATOM   3762 C CG   . TYR A 1 256 ? 93.921  96.417  118.978 1.00 42.78  ? 256 TYR A CG   1 
ATOM   3763 C CD1  . TYR A 1 256 ? 92.692  96.723  118.415 1.00 42.78  ? 256 TYR A CD1  1 
ATOM   3764 C CD2  . TYR A 1 256 ? 94.005  95.297  119.791 1.00 42.78  ? 256 TYR A CD2  1 
ATOM   3765 C CE1  . TYR A 1 256 ? 91.584  95.935  118.652 1.00 42.78  ? 256 TYR A CE1  1 
ATOM   3766 C CE2  . TYR A 1 256 ? 92.904  94.505  120.033 1.00 42.78  ? 256 TYR A CE2  1 
ATOM   3767 C CZ   . TYR A 1 256 ? 91.697  94.827  119.462 1.00 42.78  ? 256 TYR A CZ   1 
ATOM   3768 O OH   . TYR A 1 256 ? 90.599  94.036  119.706 1.00 42.78  ? 256 TYR A OH   1 
ATOM   3769 H H    . TYR A 1 256 ? 97.049  98.818  118.921 1.00 42.78  ? 256 TYR A H    1 
ATOM   3770 H HA   . TYR A 1 256 ? 94.511  99.041  119.553 1.00 42.78  ? 256 TYR A HA   1 
ATOM   3771 H HB2  . TYR A 1 256 ? 95.063  97.633  117.819 1.00 42.78  ? 256 TYR A HB2  1 
ATOM   3772 H HB3  . TYR A 1 256 ? 95.921  96.720  118.793 1.00 42.78  ? 256 TYR A HB3  1 
ATOM   3773 H HD1  . TYR A 1 256 ? 92.614  97.471  117.867 1.00 42.78  ? 256 TYR A HD1  1 
ATOM   3774 H HD2  . TYR A 1 256 ? 94.821  95.075  120.179 1.00 42.78  ? 256 TYR A HD2  1 
ATOM   3775 H HE1  . TYR A 1 256 ? 90.766  96.152  118.267 1.00 42.78  ? 256 TYR A HE1  1 
ATOM   3776 H HE2  . TYR A 1 256 ? 92.978  93.756  120.580 1.00 42.78  ? 256 TYR A HE2  1 
ATOM   3777 H HH   . TYR A 1 256 ? 89.906  94.407  119.410 1.00 42.78  ? 256 TYR A HH   1 
ATOM   3778 N N    . ALA A 1 257 ? 96.316  97.670  121.767 1.00 42.84  ? 257 ALA A N    1 
ATOM   3779 C CA   . ALA A 1 257 ? 96.295  97.144  123.128 1.00 42.84  ? 257 ALA A CA   1 
ATOM   3780 C C    . ALA A 1 257 ? 95.674  98.142  124.099 1.00 42.84  ? 257 ALA A C    1 
ATOM   3781 O O    . ALA A 1 257 ? 94.748  97.805  124.844 1.00 42.84  ? 257 ALA A O    1 
ATOM   3782 C CB   . ALA A 1 257 ? 97.711  96.777  123.569 1.00 42.84  ? 257 ALA A CB   1 
ATOM   3783 H H    . ALA A 1 257 ? 97.102  97.792  121.440 1.00 42.84  ? 257 ALA A H    1 
ATOM   3784 H HA   . ALA A 1 257 ? 95.757  96.337  123.146 1.00 42.84  ? 257 ALA A HA   1 
ATOM   3785 H HB1  . ALA A 1 257 ? 97.674  96.383  124.454 1.00 42.84  ? 257 ALA A HB1  1 
ATOM   3786 H HB2  . ALA A 1 257 ? 98.082  96.140  122.938 1.00 42.84  ? 257 ALA A HB2  1 
ATOM   3787 H HB3  . ALA A 1 257 ? 98.255  97.579  123.587 1.00 42.84  ? 257 ALA A HB3  1 
ATOM   3788 N N    . ILE A 1 258 ? 96.170  99.374  124.104 1.00 44.43  ? 258 ILE A N    1 
ATOM   3789 C CA   . ILE A 1 258 ? 95.683  100.424 124.989 1.00 44.43  ? 258 ILE A CA   1 
ATOM   3790 C C    . ILE A 1 258 ? 95.198  101.582 124.124 1.00 44.43  ? 258 ILE A C    1 
ATOM   3791 O O    . ILE A 1 258 ? 96.002  102.219 123.439 1.00 44.43  ? 258 ILE A O    1 
ATOM   3792 C CB   . ILE A 1 258 ? 96.757  100.901 125.982 1.00 44.43  ? 258 ILE A CB   1 
ATOM   3793 C CG1  . ILE A 1 258 ? 98.092  101.142 125.278 1.00 44.43  ? 258 ILE A CG1  1 
ATOM   3794 C CG2  . ILE A 1 258 ? 96.927  99.885  127.096 1.00 44.43  ? 258 ILE A CG2  1 
ATOM   3795 C CD1  . ILE A 1 258 ? 99.172  101.656 126.200 1.00 44.43  ? 258 ILE A CD1  1 
ATOM   3796 H H    . ILE A 1 258 ? 96.805  99.634  123.586 1.00 44.43  ? 258 ILE A H    1 
ATOM   3797 H HA   . ILE A 1 258 ? 94.941  100.081 125.507 1.00 44.43  ? 258 ILE A HA   1 
ATOM   3798 H HB   . ILE A 1 258 ? 96.462  101.738 126.373 1.00 44.43  ? 258 ILE A HB   1 
ATOM   3799 H HG12 . ILE A 1 258 ? 98.404  100.307 124.896 1.00 44.43  ? 258 ILE A HG12 1 
ATOM   3800 H HG13 . ILE A 1 258 ? 97.971  101.800 124.578 1.00 44.43  ? 258 ILE A HG13 1 
ATOM   3801 H HG21 . ILE A 1 258 ? 97.468  100.275 127.801 1.00 44.43  ? 258 ILE A HG21 1 
ATOM   3802 H HG22 . ILE A 1 258 ? 96.053  99.650  127.445 1.00 44.43  ? 258 ILE A HG22 1 
ATOM   3803 H HG23 . ILE A 1 258 ? 97.364  99.096  126.740 1.00 44.43  ? 258 ILE A HG23 1 
ATOM   3804 H HD11 . ILE A 1 258 ? 99.952  101.888 125.673 1.00 44.43  ? 258 ILE A HD11 1 
ATOM   3805 H HD12 . ILE A 1 258 ? 98.840  102.440 126.664 1.00 44.43  ? 258 ILE A HD12 1 
ATOM   3806 H HD13 . ILE A 1 258 ? 99.400  100.964 126.840 1.00 44.43  ? 258 ILE A HD13 1 
ATOM   3807 N N    . PRO A 1 259 ? 93.904  101.890 124.107 1.00 46.65  ? 259 PRO A N    1 
ATOM   3808 C CA   . PRO A 1 259 ? 93.423  102.971 123.241 1.00 46.65  ? 259 PRO A CA   1 
ATOM   3809 C C    . PRO A 1 259 ? 93.728  104.356 123.788 1.00 46.65  ? 259 PRO A C    1 
ATOM   3810 O O    . PRO A 1 259 ? 94.018  105.276 123.018 1.00 46.65  ? 259 PRO A O    1 
ATOM   3811 C CB   . PRO A 1 259 ? 91.915  102.711 123.178 1.00 46.65  ? 259 PRO A CB   1 
ATOM   3812 C CG   . PRO A 1 259 ? 91.604  102.087 124.486 1.00 46.65  ? 259 PRO A CG   1 
ATOM   3813 C CD   . PRO A 1 259 ? 92.802  101.257 124.854 1.00 46.65  ? 259 PRO A CD   1 
ATOM   3814 H HA   . PRO A 1 259 ? 93.801  102.886 122.353 1.00 46.65  ? 259 PRO A HA   1 
ATOM   3815 H HB2  . PRO A 1 259 ? 91.440  103.550 123.073 1.00 46.65  ? 259 PRO A HB2  1 
ATOM   3816 H HB3  . PRO A 1 259 ? 91.715  102.104 122.448 1.00 46.65  ? 259 PRO A HB3  1 
ATOM   3817 H HG2  . PRO A 1 259 ? 91.456  102.780 125.147 1.00 46.65  ? 259 PRO A HG2  1 
ATOM   3818 H HG3  . PRO A 1 259 ? 90.817  101.527 124.399 1.00 46.65  ? 259 PRO A HG3  1 
ATOM   3819 H HD2  . PRO A 1 259 ? 92.968  101.310 125.809 1.00 46.65  ? 259 PRO A HD2  1 
ATOM   3820 H HD3  . PRO A 1 259 ? 92.680  100.340 124.564 1.00 46.65  ? 259 PRO A HD3  1 
ATOM   3821 N N    . HIS A 1 260 ? 93.671  104.516 125.109 1.00 48.77  ? 260 HIS A N    1 
ATOM   3822 C CA   . HIS A 1 260 ? 93.797  105.840 125.706 1.00 48.77  ? 260 HIS A CA   1 
ATOM   3823 C C    . HIS A 1 260 ? 95.094  106.506 125.267 1.00 48.77  ? 260 HIS A C    1 
ATOM   3824 O O    . HIS A 1 260 ? 96.165  105.895 125.286 1.00 48.77  ? 260 HIS A O    1 
ATOM   3825 C CB   . HIS A 1 260 ? 93.751  105.737 127.229 1.00 48.77  ? 260 HIS A CB   1 
ATOM   3826 C CG   . HIS A 1 260 ? 92.523  105.058 127.749 1.00 48.77  ? 260 HIS A CG   1 
ATOM   3827 N ND1  . HIS A 1 260 ? 91.387  105.750 128.108 1.00 48.77  ? 260 HIS A ND1  1 
ATOM   3828 C CD2  . HIS A 1 260 ? 92.252  103.750 127.968 1.00 48.77  ? 260 HIS A CD2  1 
ATOM   3829 C CE1  . HIS A 1 260 ? 90.469  104.898 128.526 1.00 48.77  ? 260 HIS A CE1  1 
ATOM   3830 N NE2  . HIS A 1 260 ? 90.968  103.677 128.451 1.00 48.77  ? 260 HIS A NE2  1 
ATOM   3831 H H    . HIS A 1 260 ? 93.562  103.878 125.674 1.00 48.77  ? 260 HIS A H    1 
ATOM   3832 H HA   . HIS A 1 260 ? 93.057  106.395 125.415 1.00 48.77  ? 260 HIS A HA   1 
ATOM   3833 H HB2  . HIS A 1 260 ? 94.521  105.232 127.534 1.00 48.77  ? 260 HIS A HB2  1 
ATOM   3834 H HB3  . HIS A 1 260 ? 93.775  106.631 127.603 1.00 48.77  ? 260 HIS A HB3  1 
ATOM   3835 H HD2  . HIS A 1 260 ? 92.827  103.035 127.820 1.00 48.77  ? 260 HIS A HD2  1 
ATOM   3836 H HE1  . HIS A 1 260 ? 89.615  105.120 128.822 1.00 48.77  ? 260 HIS A HE1  1 
ATOM   3837 H HE2  . HIS A 1 260 ? 90.556  102.955 128.670 1.00 48.77  ? 260 HIS A HE2  1 
ATOM   3838 N N    . TRP A 1 261 ? 94.995  107.776 124.870 1.00 48.42  ? 261 TRP A N    1 
ATOM   3839 C CA   . TRP A 1 261 ? 96.157  108.456 124.307 1.00 48.42  ? 261 TRP A CA   1 
ATOM   3840 C C    . TRP A 1 261 ? 97.199  108.758 125.374 1.00 48.42  ? 261 TRP A C    1 
ATOM   3841 O O    . TRP A 1 261 ? 98.400  108.602 125.132 1.00 48.42  ? 261 TRP A O    1 
ATOM   3842 C CB   . TRP A 1 261 ? 95.729  109.741 123.603 1.00 48.42  ? 261 TRP A CB   1 
ATOM   3843 C CG   . TRP A 1 261 ? 95.450  110.872 124.529 1.00 48.42  ? 261 TRP A CG   1 
ATOM   3844 C CD1  . TRP A 1 261 ? 94.345  111.038 125.305 1.00 48.42  ? 261 TRP A CD1  1 
ATOM   3845 C CD2  . TRP A 1 261 ? 96.288  112.005 124.775 1.00 48.42  ? 261 TRP A CD2  1 
ATOM   3846 N NE1  . TRP A 1 261 ? 94.441  112.205 126.021 1.00 48.42  ? 261 TRP A NE1  1 
ATOM   3847 C CE2  . TRP A 1 261 ? 95.626  112.817 125.713 1.00 48.42  ? 261 TRP A CE2  1 
ATOM   3848 C CE3  . TRP A 1 261 ? 97.533  112.411 124.292 1.00 48.42  ? 261 TRP A CE3  1 
ATOM   3849 C CZ2  . TRP A 1 261 ? 96.167  114.009 126.180 1.00 48.42  ? 261 TRP A CZ2  1 
ATOM   3850 C CZ3  . TRP A 1 261 ? 98.066  113.595 124.755 1.00 48.42  ? 261 TRP A CZ3  1 
ATOM   3851 C CH2  . TRP A 1 261 ? 97.385  114.380 125.689 1.00 48.42  ? 261 TRP A CH2  1 
ATOM   3852 H H    . TRP A 1 261 ? 94.282  108.255 124.915 1.00 48.42  ? 261 TRP A H    1 
ATOM   3853 H HA   . TRP A 1 261 ? 96.568  107.877 123.646 1.00 48.42  ? 261 TRP A HA   1 
ATOM   3854 H HB2  . TRP A 1 261 ? 96.440  110.019 123.004 1.00 48.42  ? 261 TRP A HB2  1 
ATOM   3855 H HB3  . TRP A 1 261 ? 94.921  109.566 123.096 1.00 48.42  ? 261 TRP A HB3  1 
ATOM   3856 H HD1  . TRP A 1 261 ? 93.629  110.447 125.344 1.00 48.42  ? 261 TRP A HD1  1 
ATOM   3857 H HE1  . TRP A 1 261 ? 93.853  112.502 126.575 1.00 48.42  ? 261 TRP A HE1  1 
ATOM   3858 H HE3  . TRP A 1 261 ? 97.992  111.895 123.671 1.00 48.42  ? 261 TRP A HE3  1 
ATOM   3859 H HZ2  . TRP A 1 261 ? 95.715  114.533 126.801 1.00 48.42  ? 261 TRP A HZ2  1 
ATOM   3860 H HZ3  . TRP A 1 261 ? 98.895  113.875 124.442 1.00 48.42  ? 261 TRP A HZ3  1 
ATOM   3861 H HH2  . TRP A 1 261 ? 97.770  115.173 125.984 1.00 48.42  ? 261 TRP A HH2  1 
ATOM   3862 N N    . ARG A 1 262 ? 96.769  109.191 126.560 1.00 48.03  ? 262 ARG A N    1 
ATOM   3863 C CA   . ARG A 1 262 ? 97.734  109.520 127.603 1.00 48.03  ? 262 ARG A CA   1 
ATOM   3864 C C    . ARG A 1 262 ? 98.576  108.305 127.964 1.00 48.03  ? 262 ARG A C    1 
ATOM   3865 O O    . ARG A 1 262 ? 99.812  108.362 127.952 1.00 48.03  ? 262 ARG A O    1 
ATOM   3866 C CB   . ARG A 1 262 ? 97.014  110.060 128.838 1.00 48.03  ? 262 ARG A CB   1 
ATOM   3867 C CG   . ARG A 1 262 ? 96.291  111.371 128.608 1.00 48.03  ? 262 ARG A CG   1 
ATOM   3868 C CD   . ARG A 1 262 ? 95.730  111.928 129.903 1.00 48.03  ? 262 ARG A CD   1 
ATOM   3869 N NE   . ARG A 1 262 ? 94.977  113.157 129.685 1.00 48.03  ? 262 ARG A NE   1 
ATOM   3870 C CZ   . ARG A 1 262 ? 95.523  114.360 129.574 1.00 48.03  ? 262 ARG A CZ   1 
ATOM   3871 N NH1  . ARG A 1 262 ? 96.831  114.535 129.641 1.00 48.03  ? 262 ARG A NH1  1 
ATOM   3872 N NH2  . ARG A 1 262 ? 94.734  115.414 129.390 1.00 48.03  ? 262 ARG A NH2  1 
ATOM   3873 H H    . ARG A 1 262 ? 95.945  109.300 126.780 1.00 48.03  ? 262 ARG A H    1 
ATOM   3874 H HA   . ARG A 1 262 ? 98.330  110.213 127.277 1.00 48.03  ? 262 ARG A HA   1 
ATOM   3875 H HB2  . ARG A 1 262 ? 96.356  109.407 129.124 1.00 48.03  ? 262 ARG A HB2  1 
ATOM   3876 H HB3  . ARG A 1 262 ? 97.664  110.200 129.544 1.00 48.03  ? 262 ARG A HB3  1 
ATOM   3877 H HG2  . ARG A 1 262 ? 96.908  112.020 128.236 1.00 48.03  ? 262 ARG A HG2  1 
ATOM   3878 H HG3  . ARG A 1 262 ? 95.552  111.218 128.002 1.00 48.03  ? 262 ARG A HG3  1 
ATOM   3879 H HD2  . ARG A 1 262 ? 95.129  111.274 130.294 1.00 48.03  ? 262 ARG A HD2  1 
ATOM   3880 H HD3  . ARG A 1 262 ? 96.458  112.118 130.514 1.00 48.03  ? 262 ARG A HD3  1 
ATOM   3881 H HE   . ARG A 1 262 ? 94.130  113.088 129.551 1.00 48.03  ? 262 ARG A HE   1 
ATOM   3882 H HH11 . ARG A 1 262 ? 97.352  113.861 129.760 1.00 48.03  ? 262 ARG A HH11 1 
ATOM   3883 H HH12 . ARG A 1 262 ? 97.162  115.325 129.567 1.00 48.03  ? 262 ARG A HH12 1 
ATOM   3884 H HH21 . ARG A 1 262 ? 93.882  115.311 129.345 1.00 48.03  ? 262 ARG A HH21 1 
ATOM   3885 H HH22 . ARG A 1 262 ? 95.077  116.200 129.317 1.00 48.03  ? 262 ARG A HH22 1 
ATOM   3886 N N    . TRP A 1 263 ? 97.922  107.186 128.277 1.00 48.74  ? 263 TRP A N    1 
ATOM   3887 C CA   . TRP A 1 263 ? 98.663  105.977 128.608 1.00 48.74  ? 263 TRP A CA   1 
ATOM   3888 C C    . TRP A 1 263 ? 99.470  105.487 127.416 1.00 48.74  ? 263 TRP A C    1 
ATOM   3889 O O    . TRP A 1 263 ? 100.604 105.026 127.576 1.00 48.74  ? 263 TRP A O    1 
ATOM   3890 C CB   . TRP A 1 263 ? 97.710  104.890 129.099 1.00 48.74  ? 263 TRP A CB   1 
ATOM   3891 C CG   . TRP A 1 263 ? 97.008  105.266 130.358 1.00 48.74  ? 263 TRP A CG   1 
ATOM   3892 C CD1  . TRP A 1 263 ? 95.671  105.467 130.522 1.00 48.74  ? 263 TRP A CD1  1 
ATOM   3893 C CD2  . TRP A 1 263 ? 97.609  105.502 131.634 1.00 48.74  ? 263 TRP A CD2  1 
ATOM   3894 N NE1  . TRP A 1 263 ? 95.399  105.809 131.823 1.00 48.74  ? 263 TRP A NE1  1 
ATOM   3895 C CE2  . TRP A 1 263 ? 96.574  105.838 132.527 1.00 48.74  ? 263 TRP A CE2  1 
ATOM   3896 C CE3  . TRP A 1 263 ? 98.922  105.461 132.109 1.00 48.74  ? 263 TRP A CE3  1 
ATOM   3897 C CZ2  . TRP A 1 263 ? 96.810  106.129 133.868 1.00 48.74  ? 263 TRP A CZ2  1 
ATOM   3898 C CZ3  . TRP A 1 263 ? 99.155  105.750 133.441 1.00 48.74  ? 263 TRP A CZ3  1 
ATOM   3899 C CH2  . TRP A 1 263 ? 98.105  106.080 134.304 1.00 48.74  ? 263 TRP A CH2  1 
ATOM   3900 H H    . TRP A 1 263 ? 97.066  107.104 128.303 1.00 48.74  ? 263 TRP A H    1 
ATOM   3901 H HA   . TRP A 1 263 ? 99.284  106.177 129.327 1.00 48.74  ? 263 TRP A HA   1 
ATOM   3902 H HB2  . TRP A 1 263 ? 97.039  104.726 128.418 1.00 48.74  ? 263 TRP A HB2  1 
ATOM   3903 H HB3  . TRP A 1 263 ? 98.216  104.080 129.269 1.00 48.74  ? 263 TRP A HB3  1 
ATOM   3904 H HD1  . TRP A 1 263 ? 95.034  105.382 129.850 1.00 48.74  ? 263 TRP A HD1  1 
ATOM   3905 H HE1  . TRP A 1 263 ? 94.620  105.977 132.144 1.00 48.74  ? 263 TRP A HE1  1 
ATOM   3906 H HE3  . TRP A 1 263 ? 99.625  105.243 131.541 1.00 48.74  ? 263 TRP A HE3  1 
ATOM   3907 H HZ2  . TRP A 1 263 ? 96.114  106.348 134.444 1.00 48.74  ? 263 TRP A HZ2  1 
ATOM   3908 H HZ3  . TRP A 1 263 ? 100.025 105.726 133.768 1.00 48.74  ? 263 TRP A HZ3  1 
ATOM   3909 H HH2  . TRP A 1 263 ? 98.292  106.270 135.195 1.00 48.74  ? 263 TRP A HH2  1 
ATOM   3910 N N    . LEU A 1 264 ? 98.905  105.575 126.211 1.00 44.66  ? 264 LEU A N    1 
ATOM   3911 C CA   . LEU A 1 264 ? 99.634  105.127 125.029 1.00 44.66  ? 264 LEU A CA   1 
ATOM   3912 C C    . LEU A 1 264 ? 100.960 105.860 124.903 1.00 44.66  ? 264 LEU A C    1 
ATOM   3913 O O    . LEU A 1 264 ? 102.017 105.238 124.745 1.00 44.66  ? 264 LEU A O    1 
ATOM   3914 C CB   . LEU A 1 264 ? 98.785  105.340 123.776 1.00 44.66  ? 264 LEU A CB   1 
ATOM   3915 C CG   . LEU A 1 264 ? 99.480  105.069 122.440 1.00 44.66  ? 264 LEU A CG   1 
ATOM   3916 C CD1  . LEU A 1 264 ? 100.024 103.656 122.390 1.00 44.66  ? 264 LEU A CD1  1 
ATOM   3917 C CD2  . LEU A 1 264 ? 98.522  105.304 121.292 1.00 44.66  ? 264 LEU A CD2  1 
ATOM   3918 H H    . LEU A 1 264 ? 98.117  105.883 126.055 1.00 44.66  ? 264 LEU A H    1 
ATOM   3919 H HA   . LEU A 1 264 ? 99.819  104.179 125.112 1.00 44.66  ? 264 LEU A HA   1 
ATOM   3920 H HB2  . LEU A 1 264 ? 98.016  104.751 123.825 1.00 44.66  ? 264 LEU A HB2  1 
ATOM   3921 H HB3  . LEU A 1 264 ? 98.484  106.262 123.764 1.00 44.66  ? 264 LEU A HB3  1 
ATOM   3922 H HG   . LEU A 1 264 ? 100.224 105.682 122.336 1.00 44.66  ? 264 LEU A HG   1 
ATOM   3923 H HD11 . LEU A 1 264 ? 100.388 103.492 121.506 1.00 44.66  ? 264 LEU A HD11 1 
ATOM   3924 H HD12 . LEU A 1 264 ? 100.721 103.560 123.057 1.00 44.66  ? 264 LEU A HD12 1 
ATOM   3925 H HD13 . LEU A 1 264 ? 99.302  103.035 122.571 1.00 44.66  ? 264 LEU A HD13 1 
ATOM   3926 H HD21 . LEU A 1 264 ? 98.987  105.146 120.455 1.00 44.66  ? 264 LEU A HD21 1 
ATOM   3927 H HD22 . LEU A 1 264 ? 97.773  104.694 121.375 1.00 44.66  ? 264 LEU A HD22 1 
ATOM   3928 H HD23 . LEU A 1 264 ? 98.207  106.221 121.326 1.00 44.66  ? 264 LEU A HD23 1 
ATOM   3929 N N    . GLN A 1 265 ? 100.922 107.189 124.971 1.00 44.19  ? 265 GLN A N    1 
ATOM   3930 C CA   . GLN A 1 265 ? 102.146 107.970 124.860 1.00 44.19  ? 265 GLN A CA   1 
ATOM   3931 C C    . GLN A 1 265 ? 103.090 107.660 126.011 1.00 44.19  ? 265 GLN A C    1 
ATOM   3932 O O    . GLN A 1 265 ? 104.287 107.423 125.805 1.00 44.19  ? 265 GLN A O    1 
ATOM   3933 C CB   . GLN A 1 265 ? 101.803 109.461 124.824 1.00 44.19  ? 265 GLN A CB   1 
ATOM   3934 C CG   . GLN A 1 265 ? 102.991 110.389 124.667 1.00 44.19  ? 265 GLN A CG   1 
ATOM   3935 C CD   . GLN A 1 265 ? 103.576 110.354 123.275 1.00 44.19  ? 265 GLN A CD   1 
ATOM   3936 O OE1  . GLN A 1 265 ? 103.609 109.309 122.627 1.00 44.19  ? 265 GLN A OE1  1 
ATOM   3937 N NE2  . GLN A 1 265 ? 104.035 111.504 122.800 1.00 44.19  ? 265 GLN A NE2  1 
ATOM   3938 H H    . GLN A 1 265 ? 100.208 107.656 125.082 1.00 44.19  ? 265 GLN A H    1 
ATOM   3939 H HA   . GLN A 1 265 ? 102.592 107.737 124.032 1.00 44.19  ? 265 GLN A HA   1 
ATOM   3940 H HB2  . GLN A 1 265 ? 101.209 109.621 124.074 1.00 44.19  ? 265 GLN A HB2  1 
ATOM   3941 H HB3  . GLN A 1 265 ? 101.353 109.696 125.650 1.00 44.19  ? 265 GLN A HB3  1 
ATOM   3942 H HG2  . GLN A 1 265 ? 102.704 111.298 124.845 1.00 44.19  ? 265 GLN A HG2  1 
ATOM   3943 H HG3  . GLN A 1 265 ? 103.686 110.134 125.292 1.00 44.19  ? 265 GLN A HG3  1 
ATOM   3944 H HE21 . GLN A 1 265 ? 103.993 112.215 123.282 1.00 44.19  ? 265 GLN A HE21 1 
ATOM   3945 H HE22 . GLN A 1 265 ? 104.377 111.537 122.012 1.00 44.19  ? 265 GLN A HE22 1 
ATOM   3946 N N    . LEU A 1 266 ? 102.564 107.643 127.238 1.00 46.48  ? 266 LEU A N    1 
ATOM   3947 C CA   . LEU A 1 266 ? 103.423 107.457 128.400 1.00 46.48  ? 266 LEU A CA   1 
ATOM   3948 C C    . LEU A 1 266 ? 104.099 106.096 128.380 1.00 46.48  ? 266 LEU A C    1 
ATOM   3949 O O    . LEU A 1 266 ? 105.192 105.941 128.934 1.00 46.48  ? 266 LEU A O    1 
ATOM   3950 C CB   . LEU A 1 266 ? 102.607 107.634 129.680 1.00 46.48  ? 266 LEU A CB   1 
ATOM   3951 C CG   . LEU A 1 266 ? 103.397 107.865 130.969 1.00 46.48  ? 266 LEU A CG   1 
ATOM   3952 C CD1  . LEU A 1 266 ? 102.646 108.829 131.872 1.00 46.48  ? 266 LEU A CD1  1 
ATOM   3953 C CD2  . LEU A 1 266 ? 103.653 106.555 131.691 1.00 46.48  ? 266 LEU A CD2  1 
ATOM   3954 H H    . LEU A 1 266 ? 101.728 107.737 127.419 1.00 46.48  ? 266 LEU A H    1 
ATOM   3955 H HA   . LEU A 1 266 ? 104.116 108.135 128.390 1.00 46.48  ? 266 LEU A HA   1 
ATOM   3956 H HB2  . LEU A 1 266 ? 102.021 108.398 129.561 1.00 46.48  ? 266 LEU A HB2  1 
ATOM   3957 H HB3  . LEU A 1 266 ? 102.071 106.837 129.810 1.00 46.48  ? 266 LEU A HB3  1 
ATOM   3958 H HG   . LEU A 1 266 ? 104.254 108.262 130.750 1.00 46.48  ? 266 LEU A HG   1 
ATOM   3959 H HD11 . LEU A 1 266 ? 103.152 108.956 132.690 1.00 46.48  ? 266 LEU A HD11 1 
ATOM   3960 H HD12 . LEU A 1 266 ? 102.544 109.677 131.412 1.00 46.48  ? 266 LEU A HD12 1 
ATOM   3961 H HD13 . LEU A 1 266 ? 101.774 108.457 132.076 1.00 46.48  ? 266 LEU A HD13 1 
ATOM   3962 H HD21 . LEU A 1 266 ? 104.101 106.742 132.531 1.00 46.48  ? 266 LEU A HD21 1 
ATOM   3963 H HD22 . LEU A 1 266 ? 102.804 106.117 131.861 1.00 46.48  ? 266 LEU A HD22 1 
ATOM   3964 H HD23 . LEU A 1 266 ? 104.212 105.989 131.138 1.00 46.48  ? 266 LEU A HD23 1 
ATOM   3965 N N    . ALA A 1 267 ? 103.475 105.101 127.753 1.00 45.83  ? 267 ALA A N    1 
ATOM   3966 C CA   . ALA A 1 267 ? 104.080 103.777 127.690 1.00 45.83  ? 267 ALA A CA   1 
ATOM   3967 C C    . ALA A 1 267 ? 105.060 103.670 126.531 1.00 45.83  ? 267 ALA A C    1 
ATOM   3968 O O    . ALA A 1 267 ? 106.177 103.171 126.700 1.00 45.83  ? 267 ALA A O    1 
ATOM   3969 C CB   . ALA A 1 267 ? 102.995 102.706 127.571 1.00 45.83  ? 267 ALA A CB   1 
ATOM   3970 H H    . ALA A 1 267 ? 102.711 105.166 127.363 1.00 45.83  ? 267 ALA A H    1 
ATOM   3971 H HA   . ALA A 1 267 ? 104.570 103.615 128.512 1.00 45.83  ? 267 ALA A HA   1 
ATOM   3972 H HB1  . ALA A 1 267 ? 103.418 101.833 127.536 1.00 45.83  ? 267 ALA A HB1  1 
ATOM   3973 H HB2  . ALA A 1 267 ? 102.412 102.760 128.344 1.00 45.83  ? 267 ALA A HB2  1 
ATOM   3974 H HB3  . ALA A 1 267 ? 102.486 102.860 126.760 1.00 45.83  ? 267 ALA A HB3  1 
ATOM   3975 N N    . VAL A 1 268 ? 104.664 104.130 125.342 1.00 44.88  ? 268 VAL A N    1 
ATOM   3976 C CA   . VAL A 1 268 ? 105.525 103.969 124.179 1.00 44.88  ? 268 VAL A CA   1 
ATOM   3977 C C    . VAL A 1 268 ? 106.749 104.872 124.247 1.00 44.88  ? 268 VAL A C    1 
ATOM   3978 O O    . VAL A 1 268 ? 107.741 104.608 123.560 1.00 44.88  ? 268 VAL A O    1 
ATOM   3979 C CB   . VAL A 1 268 ? 104.739 104.233 122.882 1.00 44.88  ? 268 VAL A CB   1 
ATOM   3980 C CG1  . VAL A 1 268 ? 104.486 105.719 122.703 1.00 44.88  ? 268 VAL A CG1  1 
ATOM   3981 C CG2  . VAL A 1 268 ? 105.485 103.667 121.689 1.00 44.88  ? 268 VAL A CG2  1 
ATOM   3982 H H    . VAL A 1 268 ? 103.919 104.531 125.188 1.00 44.88  ? 268 VAL A H    1 
ATOM   3983 H HA   . VAL A 1 268 ? 105.839 103.052 124.151 1.00 44.88  ? 268 VAL A HA   1 
ATOM   3984 H HB   . VAL A 1 268 ? 103.880 103.786 122.937 1.00 44.88  ? 268 VAL A HB   1 
ATOM   3985 H HG11 . VAL A 1 268 ? 103.761 105.840 122.070 1.00 44.88  ? 268 VAL A HG11 1 
ATOM   3986 H HG12 . VAL A 1 268 ? 104.243 106.102 123.561 1.00 44.88  ? 268 VAL A HG12 1 
ATOM   3987 H HG13 . VAL A 1 268 ? 105.292 106.142 122.369 1.00 44.88  ? 268 VAL A HG13 1 
ATOM   3988 H HG21 . VAL A 1 268 ? 104.936 103.773 120.897 1.00 44.88  ? 268 VAL A HG21 1 
ATOM   3989 H HG22 . VAL A 1 268 ? 106.319 104.149 121.580 1.00 44.88  ? 268 VAL A HG22 1 
ATOM   3990 H HG23 . VAL A 1 268 ? 105.662 102.726 121.846 1.00 44.88  ? 268 VAL A HG23 1 
ATOM   3991 N N    . SER A 1 269 ? 106.713 105.939 125.050 1.00 47.41  ? 269 SER A N    1 
ATOM   3992 C CA   . SER A 1 269 ? 107.867 106.828 125.124 1.00 47.41  ? 269 SER A CA   1 
ATOM   3993 C C    . SER A 1 269 ? 108.960 106.294 126.042 1.00 47.41  ? 269 SER A C    1 
ATOM   3994 O O    . SER A 1 269 ? 110.141 106.577 125.815 1.00 47.41  ? 269 SER A O    1 
ATOM   3995 C CB   . SER A 1 269 ? 107.428 108.212 125.599 1.00 47.41  ? 269 SER A CB   1 
ATOM   3996 O OG   . SER A 1 269 ? 108.524 109.105 125.631 1.00 47.41  ? 269 SER A OG   1 
ATOM   3997 H H    . SER A 1 269 ? 106.050 106.162 125.550 1.00 47.41  ? 269 SER A H    1 
ATOM   3998 H HA   . SER A 1 269 ? 108.244 106.925 124.236 1.00 47.41  ? 269 SER A HA   1 
ATOM   3999 H HB2  . SER A 1 269 ? 106.756 108.556 124.989 1.00 47.41  ? 269 SER A HB2  1 
ATOM   4000 H HB3  . SER A 1 269 ? 107.057 108.135 126.492 1.00 47.41  ? 269 SER A HB3  1 
ATOM   4001 H HG   . SER A 1 269 ? 108.277 109.853 125.924 1.00 47.41  ? 269 SER A HG   1 
ATOM   4002 N N    . LEU A 1 270 ? 108.596 105.534 127.075 1.00 49.30  ? 270 LEU A N    1 
ATOM   4003 C CA   . LEU A 1 270 ? 109.593 105.091 128.047 1.00 49.30  ? 270 LEU A CA   1 
ATOM   4004 C C    . LEU A 1 270 ? 110.701 104.242 127.436 1.00 49.30  ? 270 LEU A C    1 
ATOM   4005 O O    . LEU A 1 270 ? 111.866 104.442 127.817 1.00 49.30  ? 270 LEU A O    1 
ATOM   4006 C CB   . LEU A 1 270 ? 108.903 104.337 129.191 1.00 49.30  ? 270 LEU A CB   1 
ATOM   4007 C CG   . LEU A 1 270 ? 108.015 105.187 130.105 1.00 49.30  ? 270 LEU A CG   1 
ATOM   4008 C CD1  . LEU A 1 270 ? 107.204 104.292 131.030 1.00 49.30  ? 270 LEU A CD1  1 
ATOM   4009 C CD2  . LEU A 1 270 ? 108.822 106.195 130.915 1.00 49.30  ? 270 LEU A CD2  1 
ATOM   4010 H H    . LEU A 1 270 ? 107.795 105.267 127.234 1.00 49.30  ? 270 LEU A H    1 
ATOM   4011 H HA   . LEU A 1 270 ? 110.016 105.877 128.425 1.00 49.30  ? 270 LEU A HA   1 
ATOM   4012 H HB2  . LEU A 1 270 ? 108.340 103.647 128.809 1.00 49.30  ? 270 LEU A HB2  1 
ATOM   4013 H HB3  . LEU A 1 270 ? 109.585 103.928 129.745 1.00 49.30  ? 270 LEU A HB3  1 
ATOM   4014 H HG   . LEU A 1 270 ? 107.396 105.685 129.553 1.00 49.30  ? 270 LEU A HG   1 
ATOM   4015 H HD11 . LEU A 1 270 ? 106.604 104.844 131.555 1.00 49.30  ? 270 LEU A HD11 1 
ATOM   4016 H HD12 . LEU A 1 270 ? 106.694 103.665 130.494 1.00 49.30  ? 270 LEU A HD12 1 
ATOM   4017 H HD13 . LEU A 1 270 ? 107.810 103.811 131.615 1.00 49.30  ? 270 LEU A HD13 1 
ATOM   4018 H HD21 . LEU A 1 270 ? 108.208 106.801 131.359 1.00 49.30  ? 270 LEU A HD21 1 
ATOM   4019 H HD22 . LEU A 1 270 ? 109.352 105.720 131.573 1.00 49.30  ? 270 LEU A HD22 1 
ATOM   4020 H HD23 . LEU A 1 270 ? 109.400 106.696 130.321 1.00 49.30  ? 270 LEU A HD23 1 
ATOM   4021 N N    . PRO A 1 271 ? 110.434 103.297 126.531 1.00 51.00  ? 271 PRO A N    1 
ATOM   4022 C CA   . PRO A 1 271 ? 111.542 102.521 125.948 1.00 51.00  ? 271 PRO A CA   1 
ATOM   4023 C C    . PRO A 1 271 ? 112.617 103.382 125.303 1.00 51.00  ? 271 PRO A C    1 
ATOM   4024 O O    . PRO A 1 271 ? 113.806 103.036 125.374 1.00 51.00  ? 271 PRO A O    1 
ATOM   4025 C CB   . PRO A 1 271 ? 110.833 101.632 124.919 1.00 51.00  ? 271 PRO A CB   1 
ATOM   4026 C CG   . PRO A 1 271 ? 109.457 101.476 125.452 1.00 51.00  ? 271 PRO A CG   1 
ATOM   4027 C CD   . PRO A 1 271 ? 109.121 102.774 126.122 1.00 51.00  ? 271 PRO A CD   1 
ATOM   4028 H HA   . PRO A 1 271 ? 111.950 101.960 126.626 1.00 51.00  ? 271 PRO A HA   1 
ATOM   4029 H HB2  . PRO A 1 271 ? 110.820 102.076 124.056 1.00 51.00  ? 271 PRO A HB2  1 
ATOM   4030 H HB3  . PRO A 1 271 ? 111.280 100.774 124.860 1.00 51.00  ? 271 PRO A HB3  1 
ATOM   4031 H HG2  . PRO A 1 271 ? 108.843 101.303 124.721 1.00 51.00  ? 271 PRO A HG2  1 
ATOM   4032 H HG3  . PRO A 1 271 ? 109.437 100.747 126.093 1.00 51.00  ? 271 PRO A HG3  1 
ATOM   4033 H HD2  . PRO A 1 271 ? 108.697 103.379 125.495 1.00 51.00  ? 271 PRO A HD2  1 
ATOM   4034 H HD3  . PRO A 1 271 ? 108.563 102.615 126.898 1.00 51.00  ? 271 PRO A HD3  1 
ATOM   4035 N N    . THR A 1 272 ? 112.241 104.497 124.674 1.00 50.52  ? 272 THR A N    1 
ATOM   4036 C CA   . THR A 1 272 ? 113.247 105.414 124.151 1.00 50.52  ? 272 THR A CA   1 
ATOM   4037 C C    . THR A 1 272 ? 114.120 105.955 125.274 1.00 50.52  ? 272 THR A C    1 
ATOM   4038 O O    . THR A 1 272 ? 115.338 106.092 125.115 1.00 50.52  ? 272 THR A O    1 
ATOM   4039 C CB   . THR A 1 272 ? 112.574 106.562 123.402 1.00 50.52  ? 272 THR A CB   1 
ATOM   4040 O OG1  . THR A 1 272 ? 111.758 106.034 122.349 1.00 50.52  ? 272 THR A OG1  1 
ATOM   4041 C CG2  . THR A 1 272 ? 113.617 107.499 122.811 1.00 50.52  ? 272 THR A CG2  1 
ATOM   4042 H H    . THR A 1 272 ? 111.427 104.739 124.541 1.00 50.52  ? 272 THR A H    1 
ATOM   4043 H HA   . THR A 1 272 ? 113.818 104.939 123.527 1.00 50.52  ? 272 THR A HA   1 
ATOM   4044 H HB   . THR A 1 272 ? 112.020 107.068 124.016 1.00 50.52  ? 272 THR A HB   1 
ATOM   4045 H HG1  . THR A 1 272 ? 111.384 106.660 121.934 1.00 50.52  ? 272 THR A HG1  1 
ATOM   4046 H HG21 . THR A 1 272 ? 113.192 108.120 122.199 1.00 50.52  ? 272 THR A HG21 1 
ATOM   4047 H HG22 . THR A 1 272 ? 114.052 108.002 123.517 1.00 50.52  ? 272 THR A HG22 1 
ATOM   4048 H HG23 . THR A 1 272 ? 114.285 106.989 122.327 1.00 50.52  ? 272 THR A HG23 1 
ATOM   4049 N N    . PHE A 1 273 ? 113.512 106.277 126.416 1.00 51.82  ? 273 PHE A N    1 
ATOM   4050 C CA   . PHE A 1 273 ? 114.289 106.712 127.571 1.00 51.82  ? 273 PHE A CA   1 
ATOM   4051 C C    . PHE A 1 273 ? 115.214 105.603 128.059 1.00 51.82  ? 273 PHE A C    1 
ATOM   4052 O O    . PHE A 1 273 ? 116.374 105.856 128.401 1.00 51.82  ? 273 PHE A O    1 
ATOM   4053 C CB   . PHE A 1 273 ? 113.345 107.155 128.687 1.00 51.82  ? 273 PHE A CB   1 
ATOM   4054 C CG   . PHE A 1 273 ? 114.007 107.974 129.751 1.00 51.82  ? 273 PHE A CG   1 
ATOM   4055 C CD1  . PHE A 1 273 ? 114.761 107.371 130.741 1.00 51.82  ? 273 PHE A CD1  1 
ATOM   4056 C CD2  . PHE A 1 273 ? 113.864 109.350 129.769 1.00 51.82  ? 273 PHE A CD2  1 
ATOM   4057 C CE1  . PHE A 1 273 ? 115.368 108.124 131.724 1.00 51.82  ? 273 PHE A CE1  1 
ATOM   4058 C CE2  . PHE A 1 273 ? 114.468 110.109 130.748 1.00 51.82  ? 273 PHE A CE2  1 
ATOM   4059 C CZ   . PHE A 1 273 ? 115.221 109.496 131.728 1.00 51.82  ? 273 PHE A CZ   1 
ATOM   4060 H H    . PHE A 1 273 ? 112.663 106.251 126.546 1.00 51.82  ? 273 PHE A H    1 
ATOM   4061 H HA   . PHE A 1 273 ? 114.836 107.473 127.317 1.00 51.82  ? 273 PHE A HA   1 
ATOM   4062 H HB2  . PHE A 1 273 ? 112.633 107.688 128.301 1.00 51.82  ? 273 PHE A HB2  1 
ATOM   4063 H HB3  . PHE A 1 273 ? 112.972 106.366 129.110 1.00 51.82  ? 273 PHE A HB3  1 
ATOM   4064 H HD1  . PHE A 1 273 ? 114.863 106.446 130.741 1.00 51.82  ? 273 PHE A HD1  1 
ATOM   4065 H HD2  . PHE A 1 273 ? 113.358 109.768 129.110 1.00 51.82  ? 273 PHE A HD2  1 
ATOM   4066 H HE1  . PHE A 1 273 ? 115.874 107.708 132.383 1.00 51.82  ? 273 PHE A HE1  1 
ATOM   4067 H HE2  . PHE A 1 273 ? 114.367 111.033 130.749 1.00 51.82  ? 273 PHE A HE2  1 
ATOM   4068 H HZ   . PHE A 1 273 ? 115.628 110.006 132.390 1.00 51.82  ? 273 PHE A HZ   1 
ATOM   4069 N N    . LEU A 1 274 ? 114.715 104.365 128.095 1.00 55.66  ? 274 LEU A N    1 
ATOM   4070 C CA   . LEU A 1 274 ? 115.528 103.244 128.558 1.00 55.66  ? 274 LEU A CA   1 
ATOM   4071 C C    . LEU A 1 274 ? 116.712 102.999 127.638 1.00 55.66  ? 274 LEU A C    1 
ATOM   4072 O O    . LEU A 1 274 ? 117.764 102.537 128.091 1.00 55.66  ? 274 LEU A O    1 
ATOM   4073 C CB   . LEU A 1 274 ? 114.671 101.982 128.662 1.00 55.66  ? 274 LEU A CB   1 
ATOM   4074 C CG   . LEU A 1 274 ? 115.380 100.700 129.111 1.00 55.66  ? 274 LEU A CG   1 
ATOM   4075 C CD1  . LEU A 1 274 ? 114.426 99.829  129.912 1.00 55.66  ? 274 LEU A CD1  1 
ATOM   4076 C CD2  . LEU A 1 274 ? 115.931 99.915  127.926 1.00 55.66  ? 274 LEU A CD2  1 
ATOM   4077 H H    . LEU A 1 274 ? 113.917 104.151 127.858 1.00 55.66  ? 274 LEU A H    1 
ATOM   4078 H HA   . LEU A 1 274 ? 115.872 103.447 129.442 1.00 55.66  ? 274 LEU A HA   1 
ATOM   4079 H HB2  . LEU A 1 274 ? 113.958 102.153 129.298 1.00 55.66  ? 274 LEU A HB2  1 
ATOM   4080 H HB3  . LEU A 1 274 ? 114.284 101.807 127.790 1.00 55.66  ? 274 LEU A HB3  1 
ATOM   4081 H HG   . LEU A 1 274 ? 116.124 100.936 129.687 1.00 55.66  ? 274 LEU A HG   1 
ATOM   4082 H HD11 . LEU A 1 274 ? 114.895 99.031  130.202 1.00 55.66  ? 274 LEU A HD11 1 
ATOM   4083 H HD12 . LEU A 1 274 ? 114.114 100.328 130.684 1.00 55.66  ? 274 LEU A HD12 1 
ATOM   4084 H HD13 . LEU A 1 274 ? 113.674 99.585  129.350 1.00 55.66  ? 274 LEU A HD13 1 
ATOM   4085 H HD21 . LEU A 1 274 ? 116.191 99.032  128.231 1.00 55.66  ? 274 LEU A HD21 1 
ATOM   4086 H HD22 . LEU A 1 274 ? 115.242 99.839  127.248 1.00 55.66  ? 274 LEU A HD22 1 
ATOM   4087 H HD23 . LEU A 1 274 ? 116.703 100.376 127.564 1.00 55.66  ? 274 LEU A HD23 1 
ATOM   4088 N N    . PHE A 1 275 ? 116.559 103.295 126.346 1.00 53.46  ? 275 PHE A N    1 
ATOM   4089 C CA   . PHE A 1 275 ? 117.686 103.153 125.430 1.00 53.46  ? 275 PHE A CA   1 
ATOM   4090 C C    . PHE A 1 275 ? 118.899 103.932 125.919 1.00 53.46  ? 275 PHE A C    1 
ATOM   4091 O O    . PHE A 1 275 ? 120.040 103.531 125.661 1.00 53.46  ? 275 PHE A O    1 
ATOM   4092 C CB   . PHE A 1 275 ? 117.305 103.620 124.026 1.00 53.46  ? 275 PHE A CB   1 
ATOM   4093 C CG   . PHE A 1 275 ? 118.484 104.015 123.185 1.00 53.46  ? 275 PHE A CG   1 
ATOM   4094 C CD1  . PHE A 1 275 ? 119.298 103.054 122.614 1.00 53.46  ? 275 PHE A CD1  1 
ATOM   4095 C CD2  . PHE A 1 275 ? 118.785 105.349 122.976 1.00 53.46  ? 275 PHE A CD2  1 
ATOM   4096 C CE1  . PHE A 1 275 ? 120.386 103.415 121.846 1.00 53.46  ? 275 PHE A CE1  1 
ATOM   4097 C CE2  . PHE A 1 275 ? 119.871 105.715 122.208 1.00 53.46  ? 275 PHE A CE2  1 
ATOM   4098 C CZ   . PHE A 1 275 ? 120.672 104.746 121.643 1.00 53.46  ? 275 PHE A CZ   1 
ATOM   4099 H H    . PHE A 1 275 ? 115.830 103.572 125.984 1.00 53.46  ? 275 PHE A H    1 
ATOM   4100 H HA   . PHE A 1 275 ? 117.933 102.216 125.378 1.00 53.46  ? 275 PHE A HA   1 
ATOM   4101 H HB2  . PHE A 1 275 ? 116.842 102.900 123.571 1.00 53.46  ? 275 PHE A HB2  1 
ATOM   4102 H HB3  . PHE A 1 275 ? 116.722 104.392 124.100 1.00 53.46  ? 275 PHE A HB3  1 
ATOM   4103 H HD1  . PHE A 1 275 ? 119.109 102.153 122.748 1.00 53.46  ? 275 PHE A HD1  1 
ATOM   4104 H HD2  . PHE A 1 275 ? 118.248 106.007 123.355 1.00 53.46  ? 275 PHE A HD2  1 
ATOM   4105 H HE1  . PHE A 1 275 ? 120.925 102.760 121.465 1.00 53.46  ? 275 PHE A HE1  1 
ATOM   4106 H HE2  . PHE A 1 275 ? 120.063 106.615 122.072 1.00 53.46  ? 275 PHE A HE2  1 
ATOM   4107 H HZ   . PHE A 1 275 ? 121.404 104.991 121.125 1.00 53.46  ? 275 PHE A HZ   1 
ATOM   4108 N N    . LEU A 1 276 ? 118.677 105.042 126.627 1.00 56.53  ? 276 LEU A N    1 
ATOM   4109 C CA   . LEU A 1 276 ? 119.795 105.798 127.179 1.00 56.53  ? 276 LEU A CA   1 
ATOM   4110 C C    . LEU A 1 276 ? 120.684 104.919 128.045 1.00 56.53  ? 276 LEU A C    1 
ATOM   4111 O O    . LEU A 1 276 ? 121.891 105.162 128.143 1.00 56.53  ? 276 LEU A O    1 
ATOM   4112 C CB   . LEU A 1 276 ? 119.278 106.983 127.996 1.00 56.53  ? 276 LEU A CB   1 
ATOM   4113 C CG   . LEU A 1 276 ? 120.300 107.686 128.894 1.00 56.53  ? 276 LEU A CG   1 
ATOM   4114 C CD1  . LEU A 1 276 ? 121.410 108.303 128.065 1.00 56.53  ? 276 LEU A CD1  1 
ATOM   4115 C CD2  . LEU A 1 276 ? 119.623 108.739 129.758 1.00 56.53  ? 276 LEU A CD2  1 
ATOM   4116 H H    . LEU A 1 276 ? 117.902 105.372 126.799 1.00 56.53  ? 276 LEU A H    1 
ATOM   4117 H HA   . LEU A 1 276 ? 120.333 106.145 126.451 1.00 56.53  ? 276 LEU A HA   1 
ATOM   4118 H HB2  . LEU A 1 276 ? 118.928 107.647 127.381 1.00 56.53  ? 276 LEU A HB2  1 
ATOM   4119 H HB3  . LEU A 1 276 ? 118.564 106.669 128.571 1.00 56.53  ? 276 LEU A HB3  1 
ATOM   4120 H HG   . LEU A 1 276 ? 120.701 107.040 129.495 1.00 56.53  ? 276 LEU A HG   1 
ATOM   4121 H HD11 . LEU A 1 276 ? 122.058 108.710 128.660 1.00 56.53  ? 276 LEU A HD11 1 
ATOM   4122 H HD12 . LEU A 1 276 ? 121.836 107.608 127.539 1.00 56.53  ? 276 LEU A HD12 1 
ATOM   4123 H HD13 . LEU A 1 276 ? 121.029 108.975 127.479 1.00 56.53  ? 276 LEU A HD13 1 
ATOM   4124 H HD21 . LEU A 1 276 ? 120.287 109.144 130.339 1.00 56.53  ? 276 LEU A HD21 1 
ATOM   4125 H HD22 . LEU A 1 276 ? 119.229 109.414 129.185 1.00 56.53  ? 276 LEU A HD22 1 
ATOM   4126 H HD23 . LEU A 1 276 ? 118.934 108.313 130.291 1.00 56.53  ? 276 LEU A HD23 1 
ATOM   4127 N N    . LEU A 1 277 ? 120.112 103.895 128.680 1.00 61.45  ? 277 LEU A N    1 
ATOM   4128 C CA   . LEU A 1 277 ? 120.895 103.040 129.563 1.00 61.45  ? 277 LEU A CA   1 
ATOM   4129 C C    . LEU A 1 277 ? 122.042 102.354 128.834 1.00 61.45  ? 277 LEU A C    1 
ATOM   4130 O O    . LEU A 1 277 ? 123.027 101.974 129.476 1.00 61.45  ? 277 LEU A O    1 
ATOM   4131 C CB   . LEU A 1 277 ? 119.984 101.997 130.214 1.00 61.45  ? 277 LEU A CB   1 
ATOM   4132 C CG   . LEU A 1 277 ? 120.575 101.206 131.384 1.00 61.45  ? 277 LEU A CG   1 
ATOM   4133 C CD1  . LEU A 1 277 ? 119.514 100.966 132.447 1.00 61.45  ? 277 LEU A CD1  1 
ATOM   4134 C CD2  . LEU A 1 277 ? 121.158 99.884  130.913 1.00 61.45  ? 277 LEU A CD2  1 
ATOM   4135 H H    . LEU A 1 277 ? 119.282 103.679 128.617 1.00 61.45  ? 277 LEU A H    1 
ATOM   4136 H HA   . LEU A 1 277 ? 121.275 103.584 130.270 1.00 61.45  ? 277 LEU A HA   1 
ATOM   4137 H HB2  . LEU A 1 277 ? 119.193 102.450 130.544 1.00 61.45  ? 277 LEU A HB2  1 
ATOM   4138 H HB3  . LEU A 1 277 ? 119.725 101.356 129.534 1.00 61.45  ? 277 LEU A HB3  1 
ATOM   4139 H HG   . LEU A 1 277 ? 121.290 101.723 131.785 1.00 61.45  ? 277 LEU A HG   1 
ATOM   4140 H HD11 . LEU A 1 277 ? 119.897 100.429 133.158 1.00 61.45  ? 277 LEU A HD11 1 
ATOM   4141 H HD12 . LEU A 1 277 ? 119.221 101.821 132.799 1.00 61.45  ? 277 LEU A HD12 1 
ATOM   4142 H HD13 . LEU A 1 277 ? 118.765 100.498 132.045 1.00 61.45  ? 277 LEU A HD13 1 
ATOM   4143 H HD21 . LEU A 1 277 ? 121.402 99.354  131.688 1.00 61.45  ? 277 LEU A HD21 1 
ATOM   4144 H HD22 . LEU A 1 277 ? 120.491 99.413  130.389 1.00 61.45  ? 277 LEU A HD22 1 
ATOM   4145 H HD23 . LEU A 1 277 ? 121.943 100.057 130.372 1.00 61.45  ? 277 LEU A HD23 1 
ATOM   4146 N N    . TYR A 1 278 ? 121.944 102.191 127.514 1.00 64.09  ? 278 TYR A N    1 
ATOM   4147 C CA   . TYR A 1 278 ? 122.999 101.581 126.714 1.00 64.09  ? 278 TYR A CA   1 
ATOM   4148 C C    . TYR A 1 278 ? 123.760 102.604 125.875 1.00 64.09  ? 278 TYR A C    1 
ATOM   4149 O O    . TYR A 1 278 ? 124.145 102.308 124.739 1.00 64.09  ? 278 TYR A O    1 
ATOM   4150 C CB   . TYR A 1 278 ? 122.418 100.489 125.815 1.00 64.09  ? 278 TYR A CB   1 
ATOM   4151 C CG   . TYR A 1 278 ? 121.921 99.256  126.545 1.00 64.09  ? 278 TYR A CG   1 
ATOM   4152 C CD1  . TYR A 1 278 ? 122.327 98.971  127.843 1.00 64.09  ? 278 TYR A CD1  1 
ATOM   4153 C CD2  . TYR A 1 278 ? 121.051 98.368  125.925 1.00 64.09  ? 278 TYR A CD2  1 
ATOM   4154 C CE1  . TYR A 1 278 ? 121.876 97.842  128.502 1.00 64.09  ? 278 TYR A CE1  1 
ATOM   4155 C CE2  . TYR A 1 278 ? 120.595 97.238  126.577 1.00 64.09  ? 278 TYR A CE2  1 
ATOM   4156 C CZ   . TYR A 1 278 ? 121.010 96.980  127.864 1.00 64.09  ? 278 TYR A CZ   1 
ATOM   4157 O OH   . TYR A 1 278 ? 120.559 95.857  128.517 1.00 64.09  ? 278 TYR A OH   1 
ATOM   4158 H H    . TYR A 1 278 ? 121.259 102.431 127.052 1.00 64.09  ? 278 TYR A H    1 
ATOM   4159 H HA   . TYR A 1 278 ? 123.648 101.173 127.306 1.00 64.09  ? 278 TYR A HA   1 
ATOM   4160 H HB2  . TYR A 1 278 ? 121.669 100.861 125.321 1.00 64.09  ? 278 TYR A HB2  1 
ATOM   4161 H HB3  . TYR A 1 278 ? 123.105 100.200 125.194 1.00 64.09  ? 278 TYR A HB3  1 
ATOM   4162 H HD1  . TYR A 1 278 ? 122.910 99.547  128.280 1.00 64.09  ? 278 TYR A HD1  1 
ATOM   4163 H HD2  . TYR A 1 278 ? 120.768 98.538  125.055 1.00 64.09  ? 278 TYR A HD2  1 
ATOM   4164 H HE1  . TYR A 1 278 ? 122.154 97.666  129.372 1.00 64.09  ? 278 TYR A HE1  1 
ATOM   4165 H HE2  . TYR A 1 278 ? 120.011 96.654  126.148 1.00 64.09  ? 278 TYR A HE2  1 
ATOM   4166 H HH   . TYR A 1 278 ? 120.053 95.415  128.012 1.00 64.09  ? 278 TYR A HH   1 
ATOM   4167 N N    . TYR A 1 279 ? 123.983 103.809 126.405 1.00 63.26  ? 279 TYR A N    1 
ATOM   4168 C CA   . TYR A 1 279 ? 124.799 104.780 125.682 1.00 63.26  ? 279 TYR A CA   1 
ATOM   4169 C C    . TYR A 1 279 ? 126.265 104.370 125.661 1.00 63.26  ? 279 TYR A C    1 
ATOM   4170 O O    . TYR A 1 279 ? 126.993 104.724 124.728 1.00 63.26  ? 279 TYR A O    1 
ATOM   4171 C CB   . TYR A 1 279 ? 124.651 106.176 126.295 1.00 63.26  ? 279 TYR A CB   1 
ATOM   4172 C CG   . TYR A 1 279 ? 125.304 106.361 127.653 1.00 63.26  ? 279 TYR A CG   1 
ATOM   4173 C CD1  . TYR A 1 279 ? 126.675 106.557 127.772 1.00 63.26  ? 279 TYR A CD1  1 
ATOM   4174 C CD2  . TYR A 1 279 ? 124.542 106.369 128.814 1.00 63.26  ? 279 TYR A CD2  1 
ATOM   4175 C CE1  . TYR A 1 279 ? 127.268 106.732 129.010 1.00 63.26  ? 279 TYR A CE1  1 
ATOM   4176 C CE2  . TYR A 1 279 ? 125.126 106.546 130.055 1.00 63.26  ? 279 TYR A CE2  1 
ATOM   4177 C CZ   . TYR A 1 279 ? 126.488 106.727 130.147 1.00 63.26  ? 279 TYR A CZ   1 
ATOM   4178 O OH   . TYR A 1 279 ? 127.068 106.903 131.383 1.00 63.26  ? 279 TYR A OH   1 
ATOM   4179 H H    . TYR A 1 279 ? 123.680 104.082 127.163 1.00 63.26  ? 279 TYR A H    1 
ATOM   4180 H HA   . TYR A 1 279 ? 124.490 104.824 124.764 1.00 63.26  ? 279 TYR A HA   1 
ATOM   4181 H HB2  . TYR A 1 279 ? 125.048 106.822 125.690 1.00 63.26  ? 279 TYR A HB2  1 
ATOM   4182 H HB3  . TYR A 1 279 ? 123.706 106.367 126.398 1.00 63.26  ? 279 TYR A HB3  1 
ATOM   4183 H HD1  . TYR A 1 279 ? 127.205 106.558 127.008 1.00 63.26  ? 279 TYR A HD1  1 
ATOM   4184 H HD2  . TYR A 1 279 ? 123.624 106.247 128.759 1.00 63.26  ? 279 TYR A HD2  1 
ATOM   4185 H HE1  . TYR A 1 279 ? 128.188 106.856 129.076 1.00 63.26  ? 279 TYR A HE1  1 
ATOM   4186 H HE2  . TYR A 1 279 ? 124.601 106.542 130.823 1.00 63.26  ? 279 TYR A HE2  1 
ATOM   4187 H HH   . TYR A 1 279 ? 126.476 106.897 131.980 1.00 63.26  ? 279 TYR A HH   1 
ATOM   4188 N N    . TRP A 1 280 ? 126.717 103.636 126.677 1.00 66.47  ? 280 TRP A N    1 
ATOM   4189 C CA   . TRP A 1 280 ? 128.125 103.285 126.798 1.00 66.47  ? 280 TRP A CA   1 
ATOM   4190 C C    . TRP A 1 280 ? 128.549 102.165 125.858 1.00 66.47  ? 280 TRP A C    1 
ATOM   4191 O O    . TRP A 1 280 ? 129.747 101.876 125.773 1.00 66.47  ? 280 TRP A O    1 
ATOM   4192 C CB   . TRP A 1 280 ? 128.441 102.877 128.239 1.00 66.47  ? 280 TRP A CB   1 
ATOM   4193 C CG   . TRP A 1 280 ? 127.809 101.583 128.654 1.00 66.47  ? 280 TRP A CG   1 
ATOM   4194 C CD1  . TRP A 1 280 ? 126.568 101.414 129.192 1.00 66.47  ? 280 TRP A CD1  1 
ATOM   4195 C CD2  . TRP A 1 280 ? 128.392 100.276 128.571 1.00 66.47  ? 280 TRP A CD2  1 
ATOM   4196 N NE1  . TRP A 1 280 ? 126.340 100.084 129.449 1.00 66.47  ? 280 TRP A NE1  1 
ATOM   4197 C CE2  . TRP A 1 280 ? 127.444 99.364  129.076 1.00 66.47  ? 280 TRP A CE2  1 
ATOM   4198 C CE3  . TRP A 1 280 ? 129.622 99.789  128.119 1.00 66.47  ? 280 TRP A CE3  1 
ATOM   4199 C CZ2  . TRP A 1 280 ? 127.687 97.994  129.141 1.00 66.47  ? 280 TRP A CZ2  1 
ATOM   4200 C CZ3  . TRP A 1 280 ? 129.861 98.428  128.184 1.00 66.47  ? 280 TRP A CZ3  1 
ATOM   4201 C CH2  . TRP A 1 280 ? 128.898 97.547  128.691 1.00 66.47  ? 280 TRP A CH2  1 
ATOM   4202 H H    . TRP A 1 280 ? 126.224 103.328 127.311 1.00 66.47  ? 280 TRP A H    1 
ATOM   4203 H HA   . TRP A 1 280 ? 128.659 104.066 126.587 1.00 66.47  ? 280 TRP A HA   1 
ATOM   4204 H HB2  . TRP A 1 280 ? 129.401 102.782 128.334 1.00 66.47  ? 280 TRP A HB2  1 
ATOM   4205 H HB3  . TRP A 1 280 ? 128.118 103.569 128.836 1.00 66.47  ? 280 TRP A HB3  1 
ATOM   4206 H HD1  . TRP A 1 280 ? 125.964 102.100 129.362 1.00 66.47  ? 280 TRP A HD1  1 
ATOM   4207 H HE1  . TRP A 1 280 ? 125.620 99.757  129.787 1.00 66.47  ? 280 TRP A HE1  1 
ATOM   4208 H HE3  . TRP A 1 280 ? 130.266 100.369 127.782 1.00 66.47  ? 280 TRP A HE3  1 
ATOM   4209 H HZ2  . TRP A 1 280 ? 127.050 97.406  129.477 1.00 66.47  ? 280 TRP A HZ2  1 
ATOM   4210 H HZ3  . TRP A 1 280 ? 130.675 98.092  127.886 1.00 66.47  ? 280 TRP A HZ3  1 
ATOM   4211 H HH2  . TRP A 1 280 ? 129.087 96.637  128.723 1.00 66.47  ? 280 TRP A HH2  1 
ATOM   4212 N N    . CYS A 1 281 ? 127.612 101.526 125.157 1.00 66.09  ? 281 CYS A N    1 
ATOM   4213 C CA   . CYS A 1 281 ? 127.970 100.400 124.300 1.00 66.09  ? 281 CYS A CA   1 
ATOM   4214 C C    . CYS A 1 281 ? 128.687 100.869 123.039 1.00 66.09  ? 281 CYS A C    1 
ATOM   4215 O O    . CYS A 1 281 ? 129.764 100.366 122.700 1.00 66.09  ? 281 CYS A O    1 
ATOM   4216 C CB   . CYS A 1 281 ? 126.718 99.599  123.941 1.00 66.09  ? 281 CYS A CB   1 
ATOM   4217 S SG   . CYS A 1 281 ? 127.045 98.148  122.917 1.00 66.09  ? 281 CYS A SG   1 
ATOM   4218 H H    . CYS A 1 281 ? 126.774 101.721 125.161 1.00 66.09  ? 281 CYS A H    1 
ATOM   4219 H HA   . CYS A 1 281 ? 128.571 99.813  124.785 1.00 66.09  ? 281 CYS A HA   1 
ATOM   4220 H HB2  . CYS A 1 281 ? 126.296 99.296  124.760 1.00 66.09  ? 281 CYS A HB2  1 
ATOM   4221 H HB3  . CYS A 1 281 ? 126.108 100.175 123.453 1.00 66.09  ? 281 CYS A HB3  1 
ATOM   4222 H HG   . CYS A 1 281 ? 126.016 97.559  122.728 1.00 66.09  ? 281 CYS A HG   1 
ATOM   4223 N N    . VAL A 1 282 ? 128.102 101.827 122.327 1.00 59.59  ? 282 VAL A N    1 
ATOM   4224 C CA   . VAL A 1 282 ? 128.641 102.278 121.045 1.00 59.59  ? 282 VAL A CA   1 
ATOM   4225 C C    . VAL A 1 282 ? 129.535 103.497 121.246 1.00 59.59  ? 282 VAL A C    1 
ATOM   4226 O O    . VAL A 1 282 ? 129.087 104.503 121.815 1.00 59.59  ? 282 VAL A O    1 
ATOM   4227 C CB   . VAL A 1 282 ? 127.514 102.583 120.045 1.00 59.59  ? 282 VAL A CB   1 
ATOM   4228 C CG1  . VAL A 1 282 ? 126.831 101.296 119.625 1.00 59.59  ? 282 VAL A CG1  1 
ATOM   4229 C CG2  . VAL A 1 282 ? 126.501 103.559 120.634 1.00 59.59  ? 282 VAL A CG2  1 
ATOM   4230 H H    . VAL A 1 282 ? 127.389 102.237 122.573 1.00 59.59  ? 282 VAL A H    1 
ATOM   4231 H HA   . VAL A 1 282 ? 129.170 101.560 120.668 1.00 59.59  ? 282 VAL A HA   1 
ATOM   4232 H HB   . VAL A 1 282 ? 127.898 102.990 119.252 1.00 59.59  ? 282 VAL A HB   1 
ATOM   4233 H HG11 . VAL A 1 282 ? 126.156 101.499 118.959 1.00 59.59  ? 282 VAL A HG11 1 
ATOM   4234 H HG12 . VAL A 1 282 ? 127.495 100.696 119.250 1.00 59.59  ? 282 VAL A HG12 1 
ATOM   4235 H HG13 . VAL A 1 282 ? 126.419 100.890 120.403 1.00 59.59  ? 282 VAL A HG13 1 
ATOM   4236 H HG21 . VAL A 1 282 ? 125.844 103.773 119.953 1.00 59.59  ? 282 VAL A HG21 1 
ATOM   4237 H HG22 . VAL A 1 282 ? 126.060 103.144 121.392 1.00 59.59  ? 282 VAL A HG22 1 
ATOM   4238 H HG23 . VAL A 1 282 ? 126.954 104.367 120.915 1.00 59.59  ? 282 VAL A HG23 1 
ATOM   4239 N N    . PRO A 1 283 ? 130.805 103.457 120.812 1.00 62.35  ? 283 PRO A N    1 
ATOM   4240 C CA   . PRO A 1 283 ? 131.644 104.659 120.890 1.00 62.35  ? 283 PRO A CA   1 
ATOM   4241 C C    . PRO A 1 283 ? 131.523 105.538 119.655 1.00 62.35  ? 283 PRO A C    1 
ATOM   4242 O O    . PRO A 1 283 ? 130.791 105.207 118.719 1.00 62.35  ? 283 PRO A O    1 
ATOM   4243 C CB   . PRO A 1 283 ? 133.055 104.081 121.030 1.00 62.35  ? 283 PRO A CB   1 
ATOM   4244 C CG   . PRO A 1 283 ? 132.995 102.813 120.261 1.00 62.35  ? 283 PRO A CG   1 
ATOM   4245 C CD   . PRO A 1 283 ? 131.591 102.274 120.420 1.00 62.35  ? 283 PRO A CD   1 
ATOM   4246 H HA   . PRO A 1 283 ? 131.428 105.177 121.682 1.00 62.35  ? 283 PRO A HA   1 
ATOM   4247 H HB2  . PRO A 1 283 ? 133.701 104.692 120.644 1.00 62.35  ? 283 PRO A HB2  1 
ATOM   4248 H HB3  . PRO A 1 283 ? 133.251 103.910 121.965 1.00 62.35  ? 283 PRO A HB3  1 
ATOM   4249 H HG2  . PRO A 1 283 ? 133.185 102.993 119.327 1.00 62.35  ? 283 PRO A HG2  1 
ATOM   4250 H HG3  . PRO A 1 283 ? 133.642 102.188 120.623 1.00 62.35  ? 283 PRO A HG3  1 
ATOM   4251 H HD2  . PRO A 1 283 ? 131.269 101.919 119.577 1.00 62.35  ? 283 PRO A HD2  1 
ATOM   4252 H HD3  . PRO A 1 283 ? 131.567 101.604 121.120 1.00 62.35  ? 283 PRO A HD3  1 
ATOM   4253 N N    . GLU A 1 284 ? 132.242 106.658 119.643 1.00 63.21  ? 284 GLU A N    1 
ATOM   4254 C CA   . GLU A 1 284 ? 132.207 107.562 118.502 1.00 63.21  ? 284 GLU A CA   1 
ATOM   4255 C C    . GLU A 1 284 ? 132.735 106.860 117.257 1.00 63.21  ? 284 GLU A C    1 
ATOM   4256 O O    . GLU A 1 284 ? 133.570 105.955 117.334 1.00 63.21  ? 284 GLU A O    1 
ATOM   4257 C CB   . GLU A 1 284 ? 133.044 108.808 118.791 1.00 63.21  ? 284 GLU A CB   1 
ATOM   4258 C CG   . GLU A 1 284 ? 132.791 109.967 117.845 1.00 63.21  ? 284 GLU A CG   1 
ATOM   4259 C CD   . GLU A 1 284 ? 131.558 110.757 118.219 1.00 63.21  ? 284 GLU A CD   1 
ATOM   4260 O OE1  . GLU A 1 284 ? 131.369 111.026 119.423 1.00 63.21  ? 284 GLU A OE1  1 
ATOM   4261 O OE2  . GLU A 1 284 ? 130.773 111.104 117.313 1.00 63.21  ? 284 GLU A OE2  1 
ATOM   4262 H H    . GLU A 1 284 ? 132.756 106.915 120.282 1.00 63.21  ? 284 GLU A H    1 
ATOM   4263 H HA   . GLU A 1 284 ? 131.292 107.838 118.337 1.00 63.21  ? 284 GLU A HA   1 
ATOM   4264 H HB2  . GLU A 1 284 ? 132.848 109.112 119.691 1.00 63.21  ? 284 GLU A HB2  1 
ATOM   4265 H HB3  . GLU A 1 284 ? 133.983 108.574 118.725 1.00 63.21  ? 284 GLU A HB3  1 
ATOM   4266 H HG2  . GLU A 1 284 ? 133.551 110.569 117.874 1.00 63.21  ? 284 GLU A HG2  1 
ATOM   4267 H HG3  . GLU A 1 284 ? 132.669 109.629 116.945 1.00 63.21  ? 284 GLU A HG3  1 
ATOM   4268 N N    . SER A 1 285 ? 132.239 107.280 116.098 1.00 61.14  ? 285 SER A N    1 
ATOM   4269 C CA   . SER A 1 285 ? 132.667 106.665 114.851 1.00 61.14  ? 285 SER A CA   1 
ATOM   4270 C C    . SER A 1 285 ? 134.152 106.939 114.616 1.00 61.14  ? 285 SER A C    1 
ATOM   4271 O O    . SER A 1 285 ? 134.613 108.067 114.822 1.00 61.14  ? 285 SER A O    1 
ATOM   4272 C CB   . SER A 1 285 ? 131.849 107.203 113.680 1.00 61.14  ? 285 SER A CB   1 
ATOM   4273 O OG   . SER A 1 285 ? 131.944 108.612 113.607 1.00 61.14  ? 285 SER A OG   1 
ATOM   4274 H H    . SER A 1 285 ? 131.662 107.912 116.009 1.00 61.14  ? 285 SER A H    1 
ATOM   4275 H HA   . SER A 1 285 ? 132.517 105.711 114.911 1.00 61.14  ? 285 SER A HA   1 
ATOM   4276 H HB2  . SER A 1 285 ? 132.190 106.820 112.857 1.00 61.14  ? 285 SER A HB2  1 
ATOM   4277 H HB3  . SER A 1 285 ? 130.921 106.957 113.800 1.00 61.14  ? 285 SER A HB3  1 
ATOM   4278 H HG   . SER A 1 285 ? 131.527 108.894 112.934 1.00 61.14  ? 285 SER A HG   1 
ATOM   4279 N N    . PRO A 1 286 ? 134.930 105.941 114.183 1.00 68.01  ? 286 PRO A N    1 
ATOM   4280 C CA   . PRO A 1 286 ? 136.365 106.200 113.976 1.00 68.01  ? 286 PRO A CA   1 
ATOM   4281 C C    . PRO A 1 286 ? 136.643 107.223 112.891 1.00 68.01  ? 286 PRO A C    1 
ATOM   4282 O O    . PRO A 1 286 ? 137.533 108.066 113.058 1.00 68.01  ? 286 PRO A O    1 
ATOM   4283 C CB   . PRO A 1 286 ? 136.925 104.818 113.607 1.00 68.01  ? 286 PRO A CB   1 
ATOM   4284 C CG   . PRO A 1 286 ? 135.903 103.842 114.058 1.00 68.01  ? 286 PRO A CG   1 
ATOM   4285 C CD   . PRO A 1 286 ? 134.590 104.534 113.919 1.00 68.01  ? 286 PRO A CD   1 
ATOM   4286 H HA   . PRO A 1 286 ? 136.773 106.497 114.805 1.00 68.01  ? 286 PRO A HA   1 
ATOM   4287 H HB2  . PRO A 1 286 ? 137.051 104.763 112.647 1.00 68.01  ? 286 PRO A HB2  1 
ATOM   4288 H HB3  . PRO A 1 286 ? 137.764 104.673 114.072 1.00 68.01  ? 286 PRO A HB3  1 
ATOM   4289 H HG2  . PRO A 1 286 ? 135.936 103.053 113.495 1.00 68.01  ? 286 PRO A HG2  1 
ATOM   4290 H HG3  . PRO A 1 286 ? 136.068 103.605 114.985 1.00 68.01  ? 286 PRO A HG3  1 
ATOM   4291 H HD2  . PRO A 1 286 ? 134.245 104.431 113.018 1.00 68.01  ? 286 PRO A HD2  1 
ATOM   4292 H HD3  . PRO A 1 286 ? 133.967 104.194 114.580 1.00 68.01  ? 286 PRO A HD3  1 
ATOM   4293 N N    . ARG A 1 287 ? 135.911 107.171 111.777 1.00 66.83  ? 287 ARG A N    1 
ATOM   4294 C CA   . ARG A 1 287 ? 136.224 108.042 110.649 1.00 66.83  ? 287 ARG A CA   1 
ATOM   4295 C C    . ARG A 1 287 ? 136.068 109.509 111.021 1.00 66.83  ? 287 ARG A C    1 
ATOM   4296 O O    . ARG A 1 287 ? 136.913 110.339 110.667 1.00 66.83  ? 287 ARG A O    1 
ATOM   4297 C CB   . ARG A 1 287 ? 135.332 107.696 109.460 1.00 66.83  ? 287 ARG A CB   1 
ATOM   4298 C CG   . ARG A 1 287 ? 135.507 106.278 108.960 1.00 66.83  ? 287 ARG A CG   1 
ATOM   4299 C CD   . ARG A 1 287 ? 134.436 105.914 107.957 1.00 66.83  ? 287 ARG A CD   1 
ATOM   4300 N NE   . ARG A 1 287 ? 134.554 104.531 107.513 1.00 66.83  ? 287 ARG A NE   1 
ATOM   4301 C CZ   . ARG A 1 287 ? 135.352 104.124 106.536 1.00 66.83  ? 287 ARG A CZ   1 
ATOM   4302 N NH1  . ARG A 1 287 ? 136.141 104.967 105.890 1.00 66.83  ? 287 ARG A NH1  1 
ATOM   4303 N NH2  . ARG A 1 287 ? 135.361 102.837 106.199 1.00 66.83  ? 287 ARG A NH2  1 
ATOM   4304 H H    . ARG A 1 287 ? 135.239 106.649 111.652 1.00 66.83  ? 287 ARG A H    1 
ATOM   4305 H HA   . ARG A 1 287 ? 137.146 107.897 110.385 1.00 66.83  ? 287 ARG A HA   1 
ATOM   4306 H HB2  . ARG A 1 287 ? 134.405 107.806 109.722 1.00 66.83  ? 287 ARG A HB2  1 
ATOM   4307 H HB3  . ARG A 1 287 ? 135.540 108.298 108.727 1.00 66.83  ? 287 ARG A HB3  1 
ATOM   4308 H HG2  . ARG A 1 287 ? 136.372 106.196 108.527 1.00 66.83  ? 287 ARG A HG2  1 
ATOM   4309 H HG3  . ARG A 1 287 ? 135.447 105.663 109.708 1.00 66.83  ? 287 ARG A HG3  1 
ATOM   4310 H HD2  . ARG A 1 287 ? 133.566 106.024 108.371 1.00 66.83  ? 287 ARG A HD2  1 
ATOM   4311 H HD3  . ARG A 1 287 ? 134.512 106.493 107.183 1.00 66.83  ? 287 ARG A HD3  1 
ATOM   4312 H HE   . ARG A 1 287 ? 134.200 103.926 108.011 1.00 66.83  ? 287 ARG A HE   1 
ATOM   4313 H HH11 . ARG A 1 287 ? 136.145 105.802 106.096 1.00 66.83  ? 287 ARG A HH11 1 
ATOM   4314 H HH12 . ARG A 1 287 ? 136.651 104.680 105.260 1.00 66.83  ? 287 ARG A HH12 1 
ATOM   4315 H HH21 . ARG A 1 287 ? 134.853 102.281 106.613 1.00 66.83  ? 287 ARG A HH21 1 
ATOM   4316 H HH22 . ARG A 1 287 ? 135.876 102.562 105.568 1.00 66.83  ? 287 ARG A HH22 1 
ATOM   4317 N N    . TRP A 1 288 ? 134.995 109.852 111.734 1.00 63.21  ? 288 TRP A N    1 
ATOM   4318 C CA   . TRP A 1 288 ? 134.796 111.241 112.127 1.00 63.21  ? 288 TRP A CA   1 
ATOM   4319 C C    . TRP A 1 288 ? 135.946 111.727 112.998 1.00 63.21  ? 288 TRP A C    1 
ATOM   4320 O O    . TRP A 1 288 ? 136.478 112.824 112.790 1.00 63.21  ? 288 TRP A O    1 
ATOM   4321 C CB   . TRP A 1 288 ? 133.465 111.396 112.859 1.00 63.21  ? 288 TRP A CB   1 
ATOM   4322 C CG   . TRP A 1 288 ? 133.418 112.615 113.714 1.00 63.21  ? 288 TRP A CG   1 
ATOM   4323 C CD1  . TRP A 1 288 ? 133.385 112.659 115.075 1.00 63.21  ? 288 TRP A CD1  1 
ATOM   4324 C CD2  . TRP A 1 288 ? 133.420 113.974 113.269 1.00 63.21  ? 288 TRP A CD2  1 
ATOM   4325 N NE1  . TRP A 1 288 ? 133.360 113.962 115.506 1.00 63.21  ? 288 TRP A NE1  1 
ATOM   4326 C CE2  . TRP A 1 288 ? 133.380 114.789 114.415 1.00 63.21  ? 288 TRP A CE2  1 
ATOM   4327 C CE3  . TRP A 1 288 ? 133.450 114.581 112.012 1.00 63.21  ? 288 TRP A CE3  1 
ATOM   4328 C CZ2  . TRP A 1 288 ? 133.370 116.177 114.342 1.00 63.21  ? 288 TRP A CZ2  1 
ATOM   4329 C CZ3  . TRP A 1 288 ? 133.438 115.960 111.942 1.00 63.21  ? 288 TRP A CZ3  1 
ATOM   4330 C CH2  . TRP A 1 288 ? 133.402 116.742 113.099 1.00 63.21  ? 288 TRP A CH2  1 
ATOM   4331 H H    . TRP A 1 288 ? 134.381 109.310 111.997 1.00 63.21  ? 288 TRP A H    1 
ATOM   4332 H HA   . TRP A 1 288 ? 134.767 111.795 111.331 1.00 63.21  ? 288 TRP A HA   1 
ATOM   4333 H HB2  . TRP A 1 288 ? 132.754 111.457 112.205 1.00 63.21  ? 288 TRP A HB2  1 
ATOM   4334 H HB3  . TRP A 1 288 ? 133.327 110.625 113.431 1.00 63.21  ? 288 TRP A HB3  1 
ATOM   4335 H HD1  . TRP A 1 288 ? 133.378 111.914 115.631 1.00 63.21  ? 288 TRP A HD1  1 
ATOM   4336 H HE1  . TRP A 1 288 ? 133.334 114.217 116.327 1.00 63.21  ? 288 TRP A HE1  1 
ATOM   4337 H HE3  . TRP A 1 288 ? 133.477 114.066 111.238 1.00 63.21  ? 288 TRP A HE3  1 
ATOM   4338 H HZ2  . TRP A 1 288 ? 133.343 116.701 115.110 1.00 63.21  ? 288 TRP A HZ2  1 
ATOM   4339 H HZ3  . TRP A 1 288 ? 133.457 116.375 111.110 1.00 63.21  ? 288 TRP A HZ3  1 
ATOM   4340 H HH2  . TRP A 1 288 ? 133.391 117.669 113.021 1.00 63.21  ? 288 TRP A HH2  1 
ATOM   4341 N N    . LEU A 1 289 ? 136.355 110.914 113.973 1.00 70.90  ? 289 LEU A N    1 
ATOM   4342 C CA   . LEU A 1 289 ? 137.470 111.303 114.830 1.00 70.90  ? 289 LEU A CA   1 
ATOM   4343 C C    . LEU A 1 289 ? 138.746 111.483 114.021 1.00 70.90  ? 289 LEU A C    1 
ATOM   4344 O O    . LEU A 1 289 ? 139.491 112.448 114.229 1.00 70.90  ? 289 LEU A O    1 
ATOM   4345 C CB   . LEU A 1 289 ? 137.678 110.260 115.927 1.00 70.90  ? 289 LEU A CB   1 
ATOM   4346 C CG   . LEU A 1 289 ? 136.645 110.246 117.053 1.00 70.90  ? 289 LEU A CG   1 
ATOM   4347 C CD1  . LEU A 1 289 ? 136.979 109.156 118.056 1.00 70.90  ? 289 LEU A CD1  1 
ATOM   4348 C CD2  . LEU A 1 289 ? 136.578 111.603 117.738 1.00 70.90  ? 289 LEU A CD2  1 
ATOM   4349 H H    . LEU A 1 289 ? 136.011 110.148 114.155 1.00 70.90  ? 289 LEU A H    1 
ATOM   4350 H HA   . LEU A 1 289 ? 137.265 112.153 115.248 1.00 70.90  ? 289 LEU A HA   1 
ATOM   4351 H HB2  . LEU A 1 289 ? 137.668 109.382 115.517 1.00 70.90  ? 289 LEU A HB2  1 
ATOM   4352 H HB3  . LEU A 1 289 ? 138.546 110.414 116.333 1.00 70.90  ? 289 LEU A HB3  1 
ATOM   4353 H HG   . LEU A 1 289 ? 135.771 110.053 116.680 1.00 70.90  ? 289 LEU A HG   1 
ATOM   4354 H HD11 . LEU A 1 289 ? 136.341 109.192 118.786 1.00 70.90  ? 289 LEU A HD11 1 
ATOM   4355 H HD12 . LEU A 1 289 ? 136.931 108.293 117.615 1.00 70.90  ? 289 LEU A HD12 1 
ATOM   4356 H HD13 . LEU A 1 289 ? 137.876 109.304 118.395 1.00 70.90  ? 289 LEU A HD13 1 
ATOM   4357 H HD21 . LEU A 1 289 ? 136.116 111.508 118.585 1.00 70.90  ? 289 LEU A HD21 1 
ATOM   4358 H HD22 . LEU A 1 289 ? 137.481 111.924 117.887 1.00 70.90  ? 289 LEU A HD22 1 
ATOM   4359 H HD23 . LEU A 1 289 ? 136.099 112.223 117.166 1.00 70.90  ? 289 LEU A HD23 1 
ATOM   4360 N N    . LEU A 1 290 ? 139.014 110.567 113.090 1.00 76.05  ? 290 LEU A N    1 
ATOM   4361 C CA   . LEU A 1 290 ? 140.221 110.680 112.280 1.00 76.05  ? 290 LEU A CA   1 
ATOM   4362 C C    . LEU A 1 290 ? 140.192 111.949 111.440 1.00 76.05  ? 290 LEU A C    1 
ATOM   4363 O O    . LEU A 1 290 ? 141.225 112.599 111.246 1.00 76.05  ? 290 LEU A O    1 
ATOM   4364 C CB   . LEU A 1 290 ? 140.373 109.450 111.387 1.00 76.05  ? 290 LEU A CB   1 
ATOM   4365 C CG   . LEU A 1 290 ? 141.756 109.273 110.759 1.00 76.05  ? 290 LEU A CG   1 
ATOM   4366 C CD1  . LEU A 1 290 ? 142.749 108.769 111.793 1.00 76.05  ? 290 LEU A CD1  1 
ATOM   4367 C CD2  . LEU A 1 290 ? 141.693 108.333 109.568 1.00 76.05  ? 290 LEU A CD2  1 
ATOM   4368 H H    . LEU A 1 290 ? 138.522 109.884 112.911 1.00 76.05  ? 290 LEU A H    1 
ATOM   4369 H HA   . LEU A 1 290 ? 140.993 110.725 112.866 1.00 76.05  ? 290 LEU A HA   1 
ATOM   4370 H HB2  . LEU A 1 290 ? 140.191 108.660 111.919 1.00 76.05  ? 290 LEU A HB2  1 
ATOM   4371 H HB3  . LEU A 1 290 ? 139.729 109.512 110.664 1.00 76.05  ? 290 LEU A HB3  1 
ATOM   4372 H HG   . LEU A 1 290 ? 142.069 110.134 110.441 1.00 76.05  ? 290 LEU A HG   1 
ATOM   4373 H HD11 . LEU A 1 290 ? 143.576 108.534 111.347 1.00 76.05  ? 290 LEU A HD11 1 
ATOM   4374 H HD12 . LEU A 1 290 ? 142.911 109.468 112.446 1.00 76.05  ? 290 LEU A HD12 1 
ATOM   4375 H HD13 . LEU A 1 290 ? 142.379 107.986 112.231 1.00 76.05  ? 290 LEU A HD13 1 
ATOM   4376 H HD21 . LEU A 1 290 ? 142.577 108.265 109.175 1.00 76.05  ? 290 LEU A HD21 1 
ATOM   4377 H HD22 . LEU A 1 290 ? 141.396 107.461 109.870 1.00 76.05  ? 290 LEU A HD22 1 
ATOM   4378 H HD23 . LEU A 1 290 ? 141.068 108.689 108.918 1.00 76.05  ? 290 LEU A HD23 1 
ATOM   4379 N N    . SER A 1 291 ? 139.015 112.316 110.933 1.00 70.51  ? 291 SER A N    1 
ATOM   4380 C CA   . SER A 1 291 ? 138.900 113.514 110.112 1.00 70.51  ? 291 SER A CA   1 
ATOM   4381 C C    . SER A 1 291 ? 139.006 114.789 110.935 1.00 70.51  ? 291 SER A C    1 
ATOM   4382 O O    . SER A 1 291 ? 139.281 115.853 110.372 1.00 70.51  ? 291 SER A O    1 
ATOM   4383 C CB   . SER A 1 291 ? 137.575 113.505 109.354 1.00 70.51  ? 291 SER A CB   1 
ATOM   4384 O OG   . SER A 1 291 ? 136.488 113.619 110.253 1.00 70.51  ? 291 SER A OG   1 
ATOM   4385 H H    . SER A 1 291 ? 138.275 111.894 111.053 1.00 70.51  ? 291 SER A H    1 
ATOM   4386 H HA   . SER A 1 291 ? 139.619 113.518 109.460 1.00 70.51  ? 291 SER A HA   1 
ATOM   4387 H HB2  . SER A 1 291 ? 137.557 114.254 108.738 1.00 70.51  ? 291 SER A HB2  1 
ATOM   4388 H HB3  . SER A 1 291 ? 137.496 112.671 108.865 1.00 70.51  ? 291 SER A HB3  1 
ATOM   4389 H HG   . SER A 1 291 ? 136.517 112.997 110.817 1.00 70.51  ? 291 SER A HG   1 
ATOM   4390 N N    . GLN A 1 292 ? 138.792 114.710 112.245 1.00 72.02  ? 292 GLN A N    1 
ATOM   4391 C CA   . GLN A 1 292 ? 138.885 115.870 113.119 1.00 72.02  ? 292 GLN A CA   1 
ATOM   4392 C C    . GLN A 1 292 ? 140.280 116.049 113.708 1.00 72.02  ? 292 GLN A C    1 
ATOM   4393 O O    . GLN A 1 292 ? 140.489 116.971 114.503 1.00 72.02  ? 292 GLN A O    1 
ATOM   4394 C CB   . GLN A 1 292 ? 137.850 115.756 114.244 1.00 72.02  ? 292 GLN A CB   1 
ATOM   4395 C CG   . GLN A 1 292 ? 137.661 117.021 115.069 1.00 72.02  ? 292 GLN A CG   1 
ATOM   4396 C CD   . GLN A 1 292 ? 137.389 118.243 114.216 1.00 72.02  ? 292 GLN A CD   1 
ATOM   4397 O OE1  . GLN A 1 292 ? 138.031 119.281 114.377 1.00 72.02  ? 292 GLN A OE1  1 
ATOM   4398 N NE2  . GLN A 1 292 ? 136.430 118.129 113.305 1.00 72.02  ? 292 GLN A NE2  1 
ATOM   4399 H H    . GLN A 1 292 ? 138.587 113.983 112.657 1.00 72.02  ? 292 GLN A H    1 
ATOM   4400 H HA   . GLN A 1 292 ? 138.682 116.661 112.598 1.00 72.02  ? 292 GLN A HA   1 
ATOM   4401 H HB2  . GLN A 1 292 ? 136.991 115.529 113.854 1.00 72.02  ? 292 GLN A HB2  1 
ATOM   4402 H HB3  . GLN A 1 292 ? 138.128 115.050 114.849 1.00 72.02  ? 292 GLN A HB3  1 
ATOM   4403 H HG2  . GLN A 1 292 ? 136.898 116.899 115.655 1.00 72.02  ? 292 GLN A HG2  1 
ATOM   4404 H HG3  . GLN A 1 292 ? 138.457 117.187 115.597 1.00 72.02  ? 292 GLN A HG3  1 
ATOM   4405 H HE21 . GLN A 1 292 ? 136.002 117.388 113.222 1.00 72.02  ? 292 GLN A HE21 1 
ATOM   4406 H HE22 . GLN A 1 292 ? 136.237 118.795 112.796 1.00 72.02  ? 292 GLN A HE22 1 
ATOM   4407 N N    . LYS A 1 293 ? 141.236 115.200 113.329 1.00 79.46  ? 293 LYS A N    1 
ATOM   4408 C CA   . LYS A 1 293 ? 142.621 115.259 113.782 1.00 79.46  ? 293 LYS A CA   1 
ATOM   4409 C C    . LYS A 1 293 ? 142.806 114.698 115.186 1.00 79.46  ? 293 LYS A C    1 
ATOM   4410 O O    . LYS A 1 293 ? 143.845 114.937 115.811 1.00 79.46  ? 293 LYS A O    1 
ATOM   4411 C CB   . LYS A 1 293 ? 143.166 116.690 113.729 1.00 79.46  ? 293 LYS A CB   1 
ATOM   4412 C CG   . LYS A 1 293 ? 144.623 116.776 113.309 1.00 79.46  ? 293 LYS A CG   1 
ATOM   4413 C CD   . LYS A 1 293 ? 145.102 118.215 113.247 1.00 79.46  ? 293 LYS A CD   1 
ATOM   4414 C CE   . LYS A 1 293 ? 145.347 118.787 114.633 1.00 79.46  ? 293 LYS A CE   1 
ATOM   4415 N NZ   . LYS A 1 293 ? 145.805 120.203 114.577 1.00 79.46  ? 293 LYS A NZ   1 
ATOM   4416 H H    . LYS A 1 293 ? 141.096 114.551 112.783 1.00 79.46  ? 293 LYS A H    1 
ATOM   4417 H HA   . LYS A 1 293 ? 143.161 114.721 113.181 1.00 79.46  ? 293 LYS A HA   1 
ATOM   4418 H HB2  . LYS A 1 293 ? 142.645 117.203 113.091 1.00 79.46  ? 293 LYS A HB2  1 
ATOM   4419 H HB3  . LYS A 1 293 ? 143.087 117.086 114.610 1.00 79.46  ? 293 LYS A HB3  1 
ATOM   4420 H HG2  . LYS A 1 293 ? 145.171 116.300 113.952 1.00 79.46  ? 293 LYS A HG2  1 
ATOM   4421 H HG3  . LYS A 1 293 ? 144.725 116.385 112.427 1.00 79.46  ? 293 LYS A HG3  1 
ATOM   4422 H HD2  . LYS A 1 293 ? 145.933 118.257 112.747 1.00 79.46  ? 293 LYS A HD2  1 
ATOM   4423 H HD3  . LYS A 1 293 ? 144.422 118.754 112.816 1.00 79.46  ? 293 LYS A HD3  1 
ATOM   4424 H HE2  . LYS A 1 293 ? 144.522 118.757 115.142 1.00 79.46  ? 293 LYS A HE2  1 
ATOM   4425 H HE3  . LYS A 1 293 ? 146.034 118.265 115.076 1.00 79.46  ? 293 LYS A HE3  1 
ATOM   4426 H HZ1  . LYS A 1 293 ? 146.071 120.468 115.383 1.00 79.46  ? 293 LYS A HZ1  1 
ATOM   4427 H HZ2  . LYS A 1 293 ? 146.484 120.280 114.007 1.00 79.46  ? 293 LYS A HZ2  1 
ATOM   4428 H HZ3  . LYS A 1 293 ? 145.139 120.727 114.304 1.00 79.46  ? 293 LYS A HZ3  1 
ATOM   4429 N N    . ARG A 1 294 ? 141.828 113.955 115.706 1.00 75.17  ? 294 ARG A N    1 
ATOM   4430 C CA   . ARG A 1 294 ? 141.953 113.290 117.002 1.00 75.17  ? 294 ARG A CA   1 
ATOM   4431 C C    . ARG A 1 294 ? 142.353 111.839 116.748 1.00 75.17  ? 294 ARG A C    1 
ATOM   4432 O O    . ARG A 1 294 ? 141.545 110.913 116.821 1.00 75.17  ? 294 ARG A O    1 
ATOM   4433 C CB   . ARG A 1 294 ? 140.652 113.400 117.792 1.00 75.17  ? 294 ARG A CB   1 
ATOM   4434 C CG   . ARG A 1 294 ? 140.426 114.772 118.411 1.00 75.17  ? 294 ARG A CG   1 
ATOM   4435 C CD   . ARG A 1 294 ? 139.180 114.802 119.284 1.00 75.17  ? 294 ARG A CD   1 
ATOM   4436 N NE   . ARG A 1 294 ? 137.953 114.814 118.498 1.00 75.17  ? 294 ARG A NE   1 
ATOM   4437 C CZ   . ARG A 1 294 ? 136.731 114.801 119.015 1.00 75.17  ? 294 ARG A CZ   1 
ATOM   4438 N NH1  . ARG A 1 294 ? 136.533 114.755 120.322 1.00 75.17  ? 294 ARG A NH1  1 
ATOM   4439 N NH2  . ARG A 1 294 ? 135.681 114.834 118.199 1.00 75.17  ? 294 ARG A NH2  1 
ATOM   4440 H H    . ARG A 1 294 ? 141.071 113.819 115.321 1.00 75.17  ? 294 ARG A H    1 
ATOM   4441 H HA   . ARG A 1 294 ? 142.657 113.714 117.518 1.00 75.17  ? 294 ARG A HA   1 
ATOM   4442 H HB2  . ARG A 1 294 ? 139.909 113.217 117.197 1.00 75.17  ? 294 ARG A HB2  1 
ATOM   4443 H HB3  . ARG A 1 294 ? 140.667 112.749 118.511 1.00 75.17  ? 294 ARG A HB3  1 
ATOM   4444 H HG2  . ARG A 1 294 ? 141.189 115.000 118.965 1.00 75.17  ? 294 ARG A HG2  1 
ATOM   4445 H HG3  . ARG A 1 294 ? 140.318 115.427 117.704 1.00 75.17  ? 294 ARG A HG3  1 
ATOM   4446 H HD2  . ARG A 1 294 ? 139.168 114.013 119.848 1.00 75.17  ? 294 ARG A HD2  1 
ATOM   4447 H HD3  . ARG A 1 294 ? 139.195 115.603 119.831 1.00 75.17  ? 294 ARG A HD3  1 
ATOM   4448 H HE   . ARG A 1 294 ? 138.025 114.885 117.644 1.00 75.17  ? 294 ARG A HE   1 
ATOM   4449 H HH11 . ARG A 1 294 ? 137.203 114.734 120.861 1.00 75.17  ? 294 ARG A HH11 1 
ATOM   4450 H HH12 . ARG A 1 294 ? 135.732 114.747 120.634 1.00 75.17  ? 294 ARG A HH12 1 
ATOM   4451 H HH21 . ARG A 1 294 ? 135.799 114.863 117.348 1.00 75.17  ? 294 ARG A HH21 1 
ATOM   4452 H HH22 . ARG A 1 294 ? 134.884 114.825 118.522 1.00 75.17  ? 294 ARG A HH22 1 
ATOM   4453 N N    . ASN A 1 295 ? 143.640 111.649 116.449 1.00 81.05  ? 295 ASN A N    1 
ATOM   4454 C CA   . ASN A 1 295 ? 144.131 110.336 116.040 1.00 81.05  ? 295 ASN A CA   1 
ATOM   4455 C C    . ASN A 1 295 ? 144.244 109.370 117.214 1.00 81.05  ? 295 ASN A C    1 
ATOM   4456 O O    . ASN A 1 295 ? 143.966 108.175 117.062 1.00 81.05  ? 295 ASN A O    1 
ATOM   4457 C CB   . ASN A 1 295 ? 145.483 110.482 115.341 1.00 81.05  ? 295 ASN A CB   1 
ATOM   4458 C CG   . ASN A 1 295 ? 146.518 111.171 116.208 1.00 81.05  ? 295 ASN A CG   1 
ATOM   4459 O OD1  . ASN A 1 295 ? 147.205 110.531 117.004 1.00 81.05  ? 295 ASN A OD1  1 
ATOM   4460 N ND2  . ASN A 1 295 ? 146.636 112.486 116.056 1.00 81.05  ? 295 ASN A ND2  1 
ATOM   4461 H H    . ASN A 1 295 ? 144.242 112.262 116.477 1.00 81.05  ? 295 ASN A H    1 
ATOM   4462 H HA   . ASN A 1 295 ? 143.507 109.955 115.402 1.00 81.05  ? 295 ASN A HA   1 
ATOM   4463 H HB2  . ASN A 1 295 ? 145.820 109.600 115.116 1.00 81.05  ? 295 ASN A HB2  1 
ATOM   4464 H HB3  . ASN A 1 295 ? 145.368 111.009 114.535 1.00 81.05  ? 295 ASN A HB3  1 
ATOM   4465 H HD21 . ASN A 1 295 ? 147.210 112.922 116.525 1.00 81.05  ? 295 ASN A HD21 1 
ATOM   4466 H HD22 . ASN A 1 295 ? 146.140 112.900 115.490 1.00 81.05  ? 295 ASN A HD22 1 
ATOM   4467 N N    . THR A 1 296 ? 144.666 109.857 118.385 1.00 83.59  ? 296 THR A N    1 
ATOM   4468 C CA   . THR A 1 296 ? 144.842 108.963 119.526 1.00 83.59  ? 296 THR A CA   1 
ATOM   4469 C C    . THR A 1 296 ? 143.520 108.319 119.928 1.00 83.59  ? 296 THR A C    1 
ATOM   4470 O O    . THR A 1 296 ? 143.462 107.111 120.190 1.00 83.59  ? 296 THR A O    1 
ATOM   4471 C CB   . THR A 1 296 ? 145.455 109.723 120.706 1.00 83.59  ? 296 THR A CB   1 
ATOM   4472 O OG1  . THR A 1 296 ? 145.707 108.814 121.784 1.00 83.59  ? 296 THR A OG1  1 
ATOM   4473 C CG2  . THR A 1 296 ? 144.528 110.832 121.191 1.00 83.59  ? 296 THR A CG2  1 
ATOM   4474 H H    . THR A 1 296 ? 144.854 110.681 118.538 1.00 83.59  ? 296 THR A H    1 
ATOM   4475 H HA   . THR A 1 296 ? 145.461 108.259 119.281 1.00 83.59  ? 296 THR A HA   1 
ATOM   4476 H HB   . THR A 1 296 ? 146.291 110.127 120.427 1.00 83.59  ? 296 THR A HB   1 
ATOM   4477 H HG1  . THR A 1 296 ? 146.067 109.220 122.425 1.00 83.59  ? 296 THR A HG1  1 
ATOM   4478 H HG21 . THR A 1 296 ? 145.017 111.441 121.767 1.00 83.59  ? 296 THR A HG21 1 
ATOM   4479 H HG22 . THR A 1 296 ? 144.176 111.328 120.436 1.00 83.59  ? 296 THR A HG22 1 
ATOM   4480 H HG23 . THR A 1 296 ? 143.789 110.452 121.691 1.00 83.59  ? 296 THR A HG23 1 
ATOM   4481 N N    . GLN A 1 297 ? 142.443 109.104 119.964 1.00 79.83  ? 297 GLN A N    1 
ATOM   4482 C CA   . GLN A 1 297 ? 141.139 108.543 120.296 1.00 79.83  ? 297 GLN A CA   1 
ATOM   4483 C C    . GLN A 1 297 ? 140.683 107.553 119.232 1.00 79.83  ? 297 GLN A C    1 
ATOM   4484 O O    . GLN A 1 297 ? 140.098 106.510 119.550 1.00 79.83  ? 297 GLN A O    1 
ATOM   4485 C CB   . GLN A 1 297 ? 140.118 109.666 120.468 1.00 79.83  ? 297 GLN A CB   1 
ATOM   4486 C CG   . GLN A 1 297 ? 140.460 110.632 121.591 1.00 79.83  ? 297 GLN A CG   1 
ATOM   4487 C CD   . GLN A 1 297 ? 139.413 111.711 121.775 1.00 79.83  ? 297 GLN A CD   1 
ATOM   4488 O OE1  . GLN A 1 297 ? 138.320 111.634 121.216 1.00 79.83  ? 297 GLN A OE1  1 
ATOM   4489 N NE2  . GLN A 1 297 ? 139.746 112.728 122.562 1.00 79.83  ? 297 GLN A NE2  1 
ATOM   4490 H H    . GLN A 1 297 ? 142.441 109.949 119.803 1.00 79.83  ? 297 GLN A H    1 
ATOM   4491 H HA   . GLN A 1 297 ? 141.205 108.067 121.139 1.00 79.83  ? 297 GLN A HA   1 
ATOM   4492 H HB2  . GLN A 1 297 ? 140.072 110.176 119.643 1.00 79.83  ? 297 GLN A HB2  1 
ATOM   4493 H HB3  . GLN A 1 297 ? 139.251 109.277 120.662 1.00 79.83  ? 297 GLN A HB3  1 
ATOM   4494 H HG2  . GLN A 1 297 ? 140.530 110.137 122.422 1.00 79.83  ? 297 GLN A HG2  1 
ATOM   4495 H HG3  . GLN A 1 297 ? 141.305 111.064 121.390 1.00 79.83  ? 297 GLN A HG3  1 
ATOM   4496 H HE21 . GLN A 1 297 ? 140.521 112.747 122.935 1.00 79.83  ? 297 GLN A HE21 1 
ATOM   4497 H HE22 . GLN A 1 297 ? 139.187 113.367 122.698 1.00 79.83  ? 297 GLN A HE22 1 
ATOM   4498 N N    . ALA A 1 298 ? 140.939 107.863 117.960 1.00 79.61  ? 298 ALA A N    1 
ATOM   4499 C CA   . ALA A 1 298 ? 140.554 106.948 116.892 1.00 79.61  ? 298 ALA A CA   1 
ATOM   4500 C C    . ALA A 1 298 ? 141.264 105.607 117.032 1.00 79.61  ? 298 ALA A C    1 
ATOM   4501 O O    . ALA A 1 298 ? 140.636 104.549 116.907 1.00 79.61  ? 298 ALA A O    1 
ATOM   4502 C CB   . ALA A 1 298 ? 140.858 107.574 115.532 1.00 79.61  ? 298 ALA A CB   1 
ATOM   4503 H H    . ALA A 1 298 ? 141.328 108.583 117.695 1.00 79.61  ? 298 ALA A H    1 
ATOM   4504 H HA   . ALA A 1 298 ? 139.599 106.788 116.941 1.00 79.61  ? 298 ALA A HA   1 
ATOM   4505 H HB1  . ALA A 1 298 ? 140.596 106.956 114.833 1.00 79.61  ? 298 ALA A HB1  1 
ATOM   4506 H HB2  . ALA A 1 298 ? 140.358 108.401 115.448 1.00 79.61  ? 298 ALA A HB2  1 
ATOM   4507 H HB3  . ALA A 1 298 ? 141.809 107.756 115.475 1.00 79.61  ? 298 ALA A HB3  1 
ATOM   4508 N N    . ILE A 1 299 ? 142.572 105.628 117.296 1.00 84.19  ? 299 ILE A N    1 
ATOM   4509 C CA   . ILE A 1 299 ? 143.300 104.371 117.451 1.00 84.19  ? 299 ILE A CA   1 
ATOM   4510 C C    . ILE A 1 299 ? 142.833 103.638 118.701 1.00 84.19  ? 299 ILE A C    1 
ATOM   4511 O O    . ILE A 1 299 ? 142.759 102.404 118.718 1.00 84.19  ? 299 ILE A O    1 
ATOM   4512 C CB   . ILE A 1 299 ? 144.822 104.608 117.468 1.00 84.19  ? 299 ILE A CB   1 
ATOM   4513 C CG1  . ILE A 1 299 ? 145.558 103.276 117.644 1.00 84.19  ? 299 ILE A CG1  1 
ATOM   4514 C CG2  . ILE A 1 299 ? 145.214 105.567 118.573 1.00 84.19  ? 299 ILE A CG2  1 
ATOM   4515 C CD1  . ILE A 1 299 ? 147.063 103.379 117.518 1.00 84.19  ? 299 ILE A CD1  1 
ATOM   4516 H H    . ILE A 1 299 ? 143.047 106.338 117.385 1.00 84.19  ? 299 ILE A H    1 
ATOM   4517 H HA   . ILE A 1 299 ? 143.102 103.805 116.689 1.00 84.19  ? 299 ILE A HA   1 
ATOM   4518 H HB   . ILE A 1 299 ? 145.084 104.994 116.617 1.00 84.19  ? 299 ILE A HB   1 
ATOM   4519 H HG12 . ILE A 1 299 ? 145.367 102.925 118.528 1.00 84.19  ? 299 ILE A HG12 1 
ATOM   4520 H HG13 . ILE A 1 299 ? 145.244 102.653 116.970 1.00 84.19  ? 299 ILE A HG13 1 
ATOM   4521 H HG21 . ILE A 1 299 ? 146.178 105.672 118.576 1.00 84.19  ? 299 ILE A HG21 1 
ATOM   4522 H HG22 . ILE A 1 299 ? 144.795 106.420 118.401 1.00 84.19  ? 299 ILE A HG22 1 
ATOM   4523 H HG23 . ILE A 1 299 ? 144.919 105.213 119.426 1.00 84.19  ? 299 ILE A HG23 1 
ATOM   4524 H HD11 . ILE A 1 299 ? 147.428 102.494 117.360 1.00 84.19  ? 299 ILE A HD11 1 
ATOM   4525 H HD12 . ILE A 1 299 ? 147.277 103.964 116.776 1.00 84.19  ? 299 ILE A HD12 1 
ATOM   4526 H HD13 . ILE A 1 299 ? 147.424 103.744 118.341 1.00 84.19  ? 299 ILE A HD13 1 
ATOM   4527 N N    . LYS A 1 300 ? 142.516 104.374 119.769 1.00 80.76  ? 300 LYS A N    1 
ATOM   4528 C CA   . LYS A 1 300 ? 141.995 103.726 120.968 1.00 80.76  ? 300 LYS A CA   1 
ATOM   4529 C C    . LYS A 1 300 ? 140.699 102.986 120.660 1.00 80.76  ? 300 LYS A C    1 
ATOM   4530 O O    . LYS A 1 300 ? 140.508 101.839 121.080 1.00 80.76  ? 300 LYS A O    1 
ATOM   4531 C CB   . LYS A 1 300 ? 141.774 104.759 122.073 1.00 80.76  ? 300 LYS A CB   1 
ATOM   4532 C CG   . LYS A 1 300 ? 141.392 104.149 123.416 1.00 80.76  ? 300 LYS A CG   1 
ATOM   4533 C CD   . LYS A 1 300 ? 141.022 105.209 124.441 1.00 80.76  ? 300 LYS A CD   1 
ATOM   4534 C CE   . LYS A 1 300 ? 139.664 105.825 124.143 1.00 80.76  ? 300 LYS A CE   1 
ATOM   4535 N NZ   . LYS A 1 300 ? 139.241 106.781 125.202 1.00 80.76  ? 300 LYS A NZ   1 
ATOM   4536 H H    . LYS A 1 300 ? 142.592 105.229 119.823 1.00 80.76  ? 300 LYS A H    1 
ATOM   4537 H HA   . LYS A 1 300 ? 142.643 103.079 121.286 1.00 80.76  ? 300 LYS A HA   1 
ATOM   4538 H HB2  . LYS A 1 300 ? 142.594 105.262 122.199 1.00 80.76  ? 300 LYS A HB2  1 
ATOM   4539 H HB3  . LYS A 1 300 ? 141.061 105.357 121.801 1.00 80.76  ? 300 LYS A HB3  1 
ATOM   4540 H HG2  . LYS A 1 300 ? 140.625 103.567 123.297 1.00 80.76  ? 300 LYS A HG2  1 
ATOM   4541 H HG3  . LYS A 1 300 ? 142.144 103.643 123.762 1.00 80.76  ? 300 LYS A HG3  1 
ATOM   4542 H HD2  . LYS A 1 300 ? 140.985 104.805 125.321 1.00 80.76  ? 300 LYS A HD2  1 
ATOM   4543 H HD3  . LYS A 1 300 ? 141.686 105.916 124.423 1.00 80.76  ? 300 LYS A HD3  1 
ATOM   4544 H HE2  . LYS A 1 300 ? 139.708 106.308 123.303 1.00 80.76  ? 300 LYS A HE2  1 
ATOM   4545 H HE3  . LYS A 1 300 ? 138.999 105.121 124.088 1.00 80.76  ? 300 LYS A HE3  1 
ATOM   4546 H HZ1  . LYS A 1 300 ? 138.443 107.121 125.002 1.00 80.76  ? 300 LYS A HZ1  1 
ATOM   4547 H HZ2  . LYS A 1 300 ? 139.189 106.363 125.986 1.00 80.76  ? 300 LYS A HZ2  1 
ATOM   4548 H HZ3  . LYS A 1 300 ? 139.830 107.445 125.266 1.00 80.76  ? 300 LYS A HZ3  1 
ATOM   4549 N N    . ILE A 1 301 ? 139.794 103.630 119.919 1.00 74.45  ? 301 ILE A N    1 
ATOM   4550 C CA   . ILE A 1 301 ? 138.532 102.983 119.570 1.00 74.45  ? 301 ILE A CA   1 
ATOM   4551 C C    . ILE A 1 301 ? 138.784 101.774 118.679 1.00 74.45  ? 301 ILE A C    1 
ATOM   4552 O O    . ILE A 1 301 ? 138.171 100.715 118.858 1.00 74.45  ? 301 ILE A O    1 
ATOM   4553 C CB   . ILE A 1 301 ? 137.574 103.986 118.900 1.00 74.45  ? 301 ILE A CB   1 
ATOM   4554 C CG1  . ILE A 1 301 ? 137.204 105.116 119.867 1.00 74.45  ? 301 ILE A CG1  1 
ATOM   4555 C CG2  . ILE A 1 301 ? 136.320 103.276 118.410 1.00 74.45  ? 301 ILE A CG2  1 
ATOM   4556 C CD1  . ILE A 1 301 ? 136.545 104.654 121.155 1.00 74.45  ? 301 ILE A CD1  1 
ATOM   4557 H H    . ILE A 1 301 ? 139.886 104.428 119.612 1.00 74.45  ? 301 ILE A H    1 
ATOM   4558 H HA   . ILE A 1 301 ? 138.111 102.660 120.382 1.00 74.45  ? 301 ILE A HA   1 
ATOM   4559 H HB   . ILE A 1 301 ? 138.024 104.374 118.133 1.00 74.45  ? 301 ILE A HB   1 
ATOM   4560 H HG12 . ILE A 1 301 ? 138.009 105.597 120.108 1.00 74.45  ? 301 ILE A HG12 1 
ATOM   4561 H HG13 . ILE A 1 301 ? 136.586 105.716 119.420 1.00 74.45  ? 301 ILE A HG13 1 
ATOM   4562 H HG21 . ILE A 1 301 ? 135.634 103.938 118.232 1.00 74.45  ? 301 ILE A HG21 1 
ATOM   4563 H HG22 . ILE A 1 301 ? 136.526 102.789 117.597 1.00 74.45  ? 301 ILE A HG22 1 
ATOM   4564 H HG23 . ILE A 1 301 ? 136.016 102.663 119.097 1.00 74.45  ? 301 ILE A HG23 1 
ATOM   4565 H HD11 . ILE A 1 301 ? 136.173 105.425 121.611 1.00 74.45  ? 301 ILE A HD11 1 
ATOM   4566 H HD12 . ILE A 1 301 ? 135.840 104.022 120.946 1.00 74.45  ? 301 ILE A HD12 1 
ATOM   4567 H HD13 . ILE A 1 301 ? 137.212 104.229 121.716 1.00 74.45  ? 301 ILE A HD13 1 
ATOM   4568 N N    . MET A 1 302 ? 139.686 101.910 117.705 1.00 79.85  ? 302 MET A N    1 
ATOM   4569 C CA   . MET A 1 302 ? 139.969 100.793 116.808 1.00 79.85  ? 302 MET A CA   1 
ATOM   4570 C C    . MET A 1 302 ? 140.523 99.600  117.575 1.00 79.85  ? 302 MET A C    1 
ATOM   4571 O O    . MET A 1 302 ? 140.159 98.451  117.298 1.00 79.85  ? 302 MET A O    1 
ATOM   4572 C CB   . MET A 1 302 ? 140.947 101.227 115.718 1.00 79.85  ? 302 MET A CB   1 
ATOM   4573 C CG   . MET A 1 302 ? 140.285 101.819 114.485 1.00 79.85  ? 302 MET A CG   1 
ATOM   4574 S SD   . MET A 1 302 ? 139.305 100.607 113.580 1.00 79.85  ? 302 MET A SD   1 
ATOM   4575 C CE   . MET A 1 302 ? 138.796 101.574 112.162 1.00 79.85  ? 302 MET A CE   1 
ATOM   4576 H H    . MET A 1 302 ? 140.138 102.624 117.546 1.00 79.85  ? 302 MET A H    1 
ATOM   4577 H HA   . MET A 1 302 ? 139.142 100.526 116.378 1.00 79.85  ? 302 MET A HA   1 
ATOM   4578 H HB2  . MET A 1 302 ? 141.544 101.898 116.083 1.00 79.85  ? 302 MET A HB2  1 
ATOM   4579 H HB3  . MET A 1 302 ? 141.460 100.453 115.435 1.00 79.85  ? 302 MET A HB3  1 
ATOM   4580 H HG2  . MET A 1 302 ? 139.695 102.539 114.758 1.00 79.85  ? 302 MET A HG2  1 
ATOM   4581 H HG3  . MET A 1 302 ? 140.971 102.157 113.889 1.00 79.85  ? 302 MET A HG3  1 
ATOM   4582 H HE1  . MET A 1 302 ? 138.294 101.005 111.557 1.00 79.85  ? 302 MET A HE1  1 
ATOM   4583 H HE2  . MET A 1 302 ? 138.240 102.309 112.463 1.00 79.85  ? 302 MET A HE2  1 
ATOM   4584 H HE3  . MET A 1 302 ? 139.585 101.916 111.715 1.00 79.85  ? 302 MET A HE3  1 
ATOM   4585 N N    . ASP A 1 303 ? 141.411 99.849  118.539 1.00 80.51  ? 303 ASP A N    1 
ATOM   4586 C CA   . ASP A 1 303 ? 141.955 98.755  119.336 1.00 80.51  ? 303 ASP A CA   1 
ATOM   4587 C C    . ASP A 1 303 ? 140.855 98.057  120.127 1.00 80.51  ? 303 ASP A C    1 
ATOM   4588 O O    . ASP A 1 303 ? 140.845 96.825  120.236 1.00 80.51  ? 303 ASP A O    1 
ATOM   4589 C CB   . ASP A 1 303 ? 143.041 99.282  120.273 1.00 80.51  ? 303 ASP A CB   1 
ATOM   4590 C CG   . ASP A 1 303 ? 143.722 98.177  121.056 1.00 80.51  ? 303 ASP A CG   1 
ATOM   4591 O OD1  . ASP A 1 303 ? 144.439 97.364  120.437 1.00 80.51  ? 303 ASP A OD1  1 
ATOM   4592 O OD2  . ASP A 1 303 ? 143.542 98.124  122.292 1.00 80.51  ? 303 ASP A OD2  1 
ATOM   4593 H H    . ASP A 1 303 ? 141.708 100.629 118.748 1.00 80.51  ? 303 ASP A H    1 
ATOM   4594 H HA   . ASP A 1 303 ? 142.359 98.102  118.744 1.00 80.51  ? 303 ASP A HA   1 
ATOM   4595 H HB2  . ASP A 1 303 ? 143.718 99.738  119.748 1.00 80.51  ? 303 ASP A HB2  1 
ATOM   4596 H HB3  . ASP A 1 303 ? 142.642 99.898  120.908 1.00 80.51  ? 303 ASP A HB3  1 
ATOM   4597 N N    . HIS A 1 304 ? 139.917 98.827  120.683 1.00 76.65  ? 304 HIS A N    1 
ATOM   4598 C CA   . HIS A 1 304 ? 138.817 98.227  121.430 1.00 76.65  ? 304 HIS A CA   1 
ATOM   4599 C C    . HIS A 1 304 ? 137.983 97.312  120.544 1.00 76.65  ? 304 HIS A C    1 
ATOM   4600 O O    . HIS A 1 304 ? 137.572 96.228  120.972 1.00 76.65  ? 304 HIS A O    1 
ATOM   4601 C CB   . HIS A 1 304 ? 137.940 99.320  122.042 1.00 76.65  ? 304 HIS A CB   1 
ATOM   4602 C CG   . HIS A 1 304 ? 136.584 98.842  122.456 1.00 76.65  ? 304 HIS A CG   1 
ATOM   4603 N ND1  . HIS A 1 304 ? 135.442 99.138  121.744 1.00 76.65  ? 304 HIS A ND1  1 
ATOM   4604 C CD2  . HIS A 1 304 ? 136.186 98.085  123.506 1.00 76.65  ? 304 HIS A CD2  1 
ATOM   4605 C CE1  . HIS A 1 304 ? 134.399 98.588  122.339 1.00 76.65  ? 304 HIS A CE1  1 
ATOM   4606 N NE2  . HIS A 1 304 ? 134.823 97.943  123.410 1.00 76.65  ? 304 HIS A NE2  1 
ATOM   4607 H H    . HIS A 1 304 ? 139.897 99.686  120.642 1.00 76.65  ? 304 HIS A H    1 
ATOM   4608 H HA   . HIS A 1 304 ? 139.180 97.694  122.155 1.00 76.65  ? 304 HIS A HA   1 
ATOM   4609 H HB2  . HIS A 1 304 ? 138.384 99.673  122.829 1.00 76.65  ? 304 HIS A HB2  1 
ATOM   4610 H HB3  . HIS A 1 304 ? 137.819 100.026 121.388 1.00 76.65  ? 304 HIS A HB3  1 
ATOM   4611 H HD2  . HIS A 1 304 ? 136.733 97.730  124.169 1.00 76.65  ? 304 HIS A HD2  1 
ATOM   4612 H HE1  . HIS A 1 304 ? 133.516 98.644  122.051 1.00 76.65  ? 304 HIS A HE1  1 
ATOM   4613 H HE2  . HIS A 1 304 ? 134.327 97.505  123.959 1.00 76.65  ? 304 HIS A HE2  1 
ATOM   4614 N N    . ILE A 1 305 ? 137.718 97.732  119.306 1.00 74.38  ? 305 ILE A N    1 
ATOM   4615 C CA   . ILE A 1 305 ? 136.957 96.888  118.390 1.00 74.38  ? 305 ILE A CA   1 
ATOM   4616 C C    . ILE A 1 305 ? 137.688 95.574  118.158 1.00 74.38  ? 305 ILE A C    1 
ATOM   4617 O O    . ILE A 1 305 ? 137.079 94.498  118.153 1.00 74.38  ? 305 ILE A O    1 
ATOM   4618 C CB   . ILE A 1 305 ? 136.696 97.628  117.065 1.00 74.38  ? 305 ILE A CB   1 
ATOM   4619 C CG1  . ILE A 1 305 ? 135.835 98.870  117.309 1.00 74.38  ? 305 ILE A CG1  1 
ATOM   4620 C CG2  . ILE A 1 305 ? 136.028 96.696  116.064 1.00 74.38  ? 305 ILE A CG2  1 
ATOM   4621 C CD1  . ILE A 1 305 ? 135.698 99.771  116.099 1.00 74.38  ? 305 ILE A CD1  1 
ATOM   4622 H H    . ILE A 1 305 ? 137.964 98.488  118.978 1.00 74.38  ? 305 ILE A H    1 
ATOM   4623 H HA   . ILE A 1 305 ? 136.097 96.684  118.792 1.00 74.38  ? 305 ILE A HA   1 
ATOM   4624 H HB   . ILE A 1 305 ? 137.549 97.913  116.699 1.00 74.38  ? 305 ILE A HB   1 
ATOM   4625 H HG12 . ILE A 1 305 ? 134.944 98.586  117.568 1.00 74.38  ? 305 ILE A HG12 1 
ATOM   4626 H HG13 . ILE A 1 305 ? 136.232 99.394  118.021 1.00 74.38  ? 305 ILE A HG13 1 
ATOM   4627 H HG21 . ILE A 1 305 ? 135.695 97.215  115.316 1.00 74.38  ? 305 ILE A HG21 1 
ATOM   4628 H HG22 . ILE A 1 305 ? 136.678 96.050  115.747 1.00 74.38  ? 305 ILE A HG22 1 
ATOM   4629 H HG23 . ILE A 1 305 ? 135.292 96.240  116.502 1.00 74.38  ? 305 ILE A HG23 1 
ATOM   4630 H HD11 . ILE A 1 305 ? 135.371 100.637 116.387 1.00 74.38  ? 305 ILE A HD11 1 
ATOM   4631 H HD12 . ILE A 1 305 ? 136.568 99.869  115.680 1.00 74.38  ? 305 ILE A HD12 1 
ATOM   4632 H HD13 . ILE A 1 305 ? 135.074 99.371  115.473 1.00 74.38  ? 305 ILE A HD13 1 
ATOM   4633 N N    . ALA A 1 306 ? 139.005 95.641  117.958 1.00 79.74  ? 306 ALA A N    1 
ATOM   4634 C CA   . ALA A 1 306 ? 139.783 94.422  117.767 1.00 79.74  ? 306 ALA A CA   1 
ATOM   4635 C C    . ALA A 1 306 ? 139.760 93.553  119.017 1.00 79.74  ? 306 ALA A C    1 
ATOM   4636 O O    . ALA A 1 306 ? 139.645 92.325  118.928 1.00 79.74  ? 306 ALA A O    1 
ATOM   4637 C CB   . ALA A 1 306 ? 141.220 94.776  117.386 1.00 79.74  ? 306 ALA A CB   1 
ATOM   4638 H H    . ALA A 1 306 ? 139.464 96.368  117.930 1.00 79.74  ? 306 ALA A H    1 
ATOM   4639 H HA   . ALA A 1 306 ? 139.397 93.910  117.039 1.00 79.74  ? 306 ALA A HA   1 
ATOM   4640 H HB1  . ALA A 1 306 ? 141.726 93.958  117.263 1.00 79.74  ? 306 ALA A HB1  1 
ATOM   4641 H HB2  . ALA A 1 306 ? 141.210 95.287  116.561 1.00 79.74  ? 306 ALA A HB2  1 
ATOM   4642 H HB3  . ALA A 1 306 ? 141.613 95.305  118.098 1.00 79.74  ? 306 ALA A HB3  1 
ATOM   4643 N N    . GLN A 1 307 ? 139.872 94.173  120.194 1.00 77.26  ? 307 GLN A N    1 
ATOM   4644 C CA   . GLN A 1 307 ? 139.920 93.405  121.434 1.00 77.26  ? 307 GLN A CA   1 
ATOM   4645 C C    . GLN A 1 307 ? 138.618 92.647  121.662 1.00 77.26  ? 307 GLN A C    1 
ATOM   4646 O O    . GLN A 1 307 ? 138.629 91.458  121.998 1.00 77.26  ? 307 GLN A O    1 
ATOM   4647 C CB   . GLN A 1 307 ? 140.217 94.338  122.608 1.00 77.26  ? 307 GLN A CB   1 
ATOM   4648 C CG   . GLN A 1 307 ? 140.426 93.622  123.933 1.00 77.26  ? 307 GLN A CG   1 
ATOM   4649 C CD   . GLN A 1 307 ? 140.802 94.568  125.057 1.00 77.26  ? 307 GLN A CD   1 
ATOM   4650 O OE1  . GLN A 1 307 ? 141.689 94.274  125.859 1.00 77.26  ? 307 GLN A OE1  1 
ATOM   4651 N NE2  . GLN A 1 307 ? 140.126 95.710  125.126 1.00 77.26  ? 307 GLN A NE2  1 
ATOM   4652 H H    . GLN A 1 307 ? 139.921 95.025  120.300 1.00 77.26  ? 307 GLN A H    1 
ATOM   4653 H HA   . GLN A 1 307 ? 140.639 92.756  121.377 1.00 77.26  ? 307 GLN A HA   1 
ATOM   4654 H HB2  . GLN A 1 307 ? 141.024 94.839  122.413 1.00 77.26  ? 307 GLN A HB2  1 
ATOM   4655 H HB3  . GLN A 1 307 ? 139.469 94.947  122.714 1.00 77.26  ? 307 GLN A HB3  1 
ATOM   4656 H HG2  . GLN A 1 307 ? 139.604 93.171  124.183 1.00 77.26  ? 307 GLN A HG2  1 
ATOM   4657 H HG3  . GLN A 1 307 ? 141.142 92.975  123.832 1.00 77.26  ? 307 GLN A HG3  1 
ATOM   4658 H HE21 . GLN A 1 307 ? 139.511 95.884  124.551 1.00 77.26  ? 307 GLN A HE21 1 
ATOM   4659 H HE22 . GLN A 1 307 ? 140.305 96.277  125.747 1.00 77.26  ? 307 GLN A HE22 1 
ATOM   4660 N N    . LYS A 1 308 ? 137.479 93.322  121.484 1.00 74.22  ? 308 LYS A N    1 
ATOM   4661 C CA   . LYS A 1 308 ? 136.197 92.649  121.666 1.00 74.22  ? 308 LYS A CA   1 
ATOM   4662 C C    . LYS A 1 308 ? 135.979 91.591  120.596 1.00 74.22  ? 308 LYS A C    1 
ATOM   4663 O O    . LYS A 1 308 ? 135.466 90.504  120.885 1.00 74.22  ? 308 LYS A O    1 
ATOM   4664 C CB   . LYS A 1 308 ? 135.057 93.668  121.645 1.00 74.22  ? 308 LYS A CB   1 
ATOM   4665 C CG   . LYS A 1 308 ? 133.679 93.065  121.900 1.00 74.22  ? 308 LYS A CG   1 
ATOM   4666 C CD   . LYS A 1 308 ? 132.565 94.032  121.530 1.00 74.22  ? 308 LYS A CD   1 
ATOM   4667 C CE   . LYS A 1 308 ? 132.450 95.177  122.521 1.00 74.22  ? 308 LYS A CE   1 
ATOM   4668 N NZ   . LYS A 1 308 ? 131.900 94.730  123.830 1.00 74.22  ? 308 LYS A NZ   1 
ATOM   4669 H H    . LYS A 1 308 ? 137.424 94.151  121.262 1.00 74.22  ? 308 LYS A H    1 
ATOM   4670 H HA   . LYS A 1 308 ? 136.191 92.209  122.531 1.00 74.22  ? 308 LYS A HA   1 
ATOM   4671 H HB2  . LYS A 1 308 ? 135.222 94.332  122.332 1.00 74.22  ? 308 LYS A HB2  1 
ATOM   4672 H HB3  . LYS A 1 308 ? 135.037 94.094  120.774 1.00 74.22  ? 308 LYS A HB3  1 
ATOM   4673 H HG2  . LYS A 1 308 ? 133.567 92.262  121.368 1.00 74.22  ? 308 LYS A HG2  1 
ATOM   4674 H HG3  . LYS A 1 308 ? 133.594 92.855  122.844 1.00 74.22  ? 308 LYS A HG3  1 
ATOM   4675 H HD2  . LYS A 1 308 ? 132.747 94.408  120.655 1.00 74.22  ? 308 LYS A HD2  1 
ATOM   4676 H HD3  . LYS A 1 308 ? 131.720 93.555  121.519 1.00 74.22  ? 308 LYS A HD3  1 
ATOM   4677 H HE2  . LYS A 1 308 ? 133.329 95.557  122.677 1.00 74.22  ? 308 LYS A HE2  1 
ATOM   4678 H HE3  . LYS A 1 308 ? 131.855 95.853  122.159 1.00 74.22  ? 308 LYS A HE3  1 
ATOM   4679 H HZ1  . LYS A 1 308 ? 131.798 95.429  124.371 1.00 74.22  ? 308 LYS A HZ1  1 
ATOM   4680 H HZ2  . LYS A 1 308 ? 131.109 94.340  123.709 1.00 74.22  ? 308 LYS A HZ2  1 
ATOM   4681 H HZ3  . LYS A 1 308 ? 132.455 94.147  124.210 1.00 74.22  ? 308 LYS A HZ3  1 
ATOM   4682 N N    . ASN A 1 309 ? 136.360 91.889  119.353 1.00 77.80  ? 309 ASN A N    1 
ATOM   4683 C CA   . ASN A 1 309 ? 136.211 90.907  118.286 1.00 77.80  ? 309 ASN A CA   1 
ATOM   4684 C C    . ASN A 1 309 ? 137.174 89.744  118.471 1.00 77.80  ? 309 ASN A C    1 
ATOM   4685 O O    . ASN A 1 309 ? 136.841 88.604  118.126 1.00 77.80  ? 309 ASN A O    1 
ATOM   4686 C CB   . ASN A 1 309 ? 136.424 91.573  116.929 1.00 77.80  ? 309 ASN A CB   1 
ATOM   4687 C CG   . ASN A 1 309 ? 136.030 90.678  115.776 1.00 77.80  ? 309 ASN A CG   1 
ATOM   4688 O OD1  . ASN A 1 309 ? 135.524 89.575  115.977 1.00 77.80  ? 309 ASN A OD1  1 
ATOM   4689 N ND2  . ASN A 1 309 ? 136.250 91.154  114.557 1.00 77.80  ? 309 ASN A ND2  1 
ATOM   4690 H H    . ASN A 1 309 ? 136.702 92.639  119.107 1.00 77.80  ? 309 ASN A H    1 
ATOM   4691 H HA   . ASN A 1 309 ? 135.307 90.554  118.308 1.00 77.80  ? 309 ASN A HA   1 
ATOM   4692 H HB2  . ASN A 1 309 ? 135.883 92.378  116.884 1.00 77.80  ? 309 ASN A HB2  1 
ATOM   4693 H HB3  . ASN A 1 309 ? 137.362 91.797  116.830 1.00 77.80  ? 309 ASN A HB3  1 
ATOM   4694 H HD21 . ASN A 1 309 ? 136.043 90.684  113.868 1.00 77.80  ? 309 ASN A HD21 1 
ATOM   4695 H HD22 . ASN A 1 309 ? 136.604 91.932  114.457 1.00 77.80  ? 309 ASN A HD22 1 
ATOM   4696 N N    . GLY A 1 310 ? 138.363 90.009  119.002 1.00 82.36  ? 310 GLY A N    1 
ATOM   4697 C CA   . GLY A 1 310 ? 139.246 88.961  119.465 1.00 82.36  ? 310 GLY A CA   1 
ATOM   4698 C C    . GLY A 1 310 ? 140.160 88.346  118.431 1.00 82.36  ? 310 GLY A C    1 
ATOM   4699 O O    . GLY A 1 310 ? 140.722 87.276  118.693 1.00 82.36  ? 310 GLY A O    1 
ATOM   4700 H H    . GLY A 1 310 ? 138.681 90.802  119.103 1.00 82.36  ? 310 GLY A H    1 
ATOM   4701 H HA2  . GLY A 1 310 ? 139.803 89.316  120.176 1.00 82.36  ? 310 GLY A HA2  1 
ATOM   4702 H HA3  . GLY A 1 310 ? 138.707 88.247  119.841 1.00 82.36  ? 310 GLY A HA3  1 
ATOM   4703 N N    . LYS A 1 311 ? 140.335 88.972  117.266 1.00 84.04  ? 311 LYS A N    1 
ATOM   4704 C CA   . LYS A 1 311 ? 141.229 88.392  116.265 1.00 84.04  ? 311 LYS A CA   1 
ATOM   4705 C C    . LYS A 1 311 ? 142.686 88.720  116.578 1.00 84.04  ? 311 LYS A C    1 
ATOM   4706 O O    . LYS A 1 311 ? 143.465 87.840  116.954 1.00 84.04  ? 311 LYS A O    1 
ATOM   4707 C CB   . LYS A 1 311 ? 140.849 88.891  114.867 1.00 84.04  ? 311 LYS A CB   1 
ATOM   4708 C CG   . LYS A 1 311 ? 139.560 88.305  114.325 1.00 84.04  ? 311 LYS A CG   1 
ATOM   4709 C CD   . LYS A 1 311 ? 139.446 88.539  112.829 1.00 84.04  ? 311 LYS A CD   1 
ATOM   4710 C CE   . LYS A 1 311 ? 138.128 88.022  112.283 1.00 84.04  ? 311 LYS A CE   1 
ATOM   4711 N NZ   . LYS A 1 311 ? 137.406 89.072  111.517 1.00 84.04  ? 311 LYS A NZ   1 
ATOM   4712 H H    . LYS A 1 311 ? 139.959 89.711  117.036 1.00 84.04  ? 311 LYS A H    1 
ATOM   4713 H HA   . LYS A 1 311 ? 141.130 87.427  116.274 1.00 84.04  ? 311 LYS A HA   1 
ATOM   4714 H HB2  . LYS A 1 311 ? 140.744 89.854  114.900 1.00 84.04  ? 311 LYS A HB2  1 
ATOM   4715 H HB3  . LYS A 1 311 ? 141.561 88.660  114.250 1.00 84.04  ? 311 LYS A HB3  1 
ATOM   4716 H HG2  . LYS A 1 311 ? 139.546 87.349  114.489 1.00 84.04  ? 311 LYS A HG2  1 
ATOM   4717 H HG3  . LYS A 1 311 ? 138.806 88.733  114.760 1.00 84.04  ? 311 LYS A HG3  1 
ATOM   4718 H HD2  . LYS A 1 311 ? 139.500 89.491  112.648 1.00 84.04  ? 311 LYS A HD2  1 
ATOM   4719 H HD3  . LYS A 1 311 ? 140.165 88.070  112.378 1.00 84.04  ? 311 LYS A HD3  1 
ATOM   4720 H HE2  . LYS A 1 311 ? 138.299 87.276  111.687 1.00 84.04  ? 311 LYS A HE2  1 
ATOM   4721 H HE3  . LYS A 1 311 ? 137.563 87.740  113.020 1.00 84.04  ? 311 LYS A HE3  1 
ATOM   4722 H HZ1  . LYS A 1 311 ? 136.601 88.779  111.280 1.00 84.04  ? 311 LYS A HZ1  1 
ATOM   4723 H HZ2  . LYS A 1 311 ? 137.313 89.800  112.020 1.00 84.04  ? 311 LYS A HZ2  1 
ATOM   4724 H HZ3  . LYS A 1 311 ? 137.866 89.285  110.785 1.00 84.04  ? 311 LYS A HZ3  1 
ATOM   4725 N N    . LEU A 1 312 ? 143.064 89.992  116.447 1.00 88.46  ? 312 LEU A N    1 
ATOM   4726 C CA   . LEU A 1 312 ? 144.409 90.439  116.787 1.00 88.46  ? 312 LEU A CA   1 
ATOM   4727 C C    . LEU A 1 312 ? 144.495 91.951  116.614 1.00 88.46  ? 312 LEU A C    1 
ATOM   4728 O O    . LEU A 1 312 ? 143.749 92.520  115.807 1.00 88.46  ? 312 LEU A O    1 
ATOM   4729 C CB   . LEU A 1 312 ? 145.453 89.743  115.906 1.00 88.46  ? 312 LEU A CB   1 
ATOM   4730 C CG   . LEU A 1 312 ? 146.867 89.592  116.473 1.00 88.46  ? 312 LEU A CG   1 
ATOM   4731 C CD1  . LEU A 1 312 ? 146.852 88.772  117.755 1.00 88.46  ? 312 LEU A CD1  1 
ATOM   4732 C CD2  . LEU A 1 312 ? 147.779 88.950  115.441 1.00 88.46  ? 312 LEU A CD2  1 
ATOM   4733 H H    . LEU A 1 312 ? 142.553 90.619  116.156 1.00 88.46  ? 312 LEU A H    1 
ATOM   4734 H HA   . LEU A 1 312 ? 144.586 90.219  117.714 1.00 88.46  ? 312 LEU A HA   1 
ATOM   4735 H HB2  . LEU A 1 312 ? 145.142 88.852  115.690 1.00 88.46  ? 312 LEU A HB2  1 
ATOM   4736 H HB3  . LEU A 1 312 ? 145.534 90.254  115.085 1.00 88.46  ? 312 LEU A HB3  1 
ATOM   4737 H HG   . LEU A 1 312 ? 147.223 90.470  116.676 1.00 88.46  ? 312 LEU A HG   1 
ATOM   4738 H HD11 . LEU A 1 312 ? 147.763 88.532  117.986 1.00 88.46  ? 312 LEU A HD11 1 
ATOM   4739 H HD12 . LEU A 1 312 ? 146.459 89.300  118.467 1.00 88.46  ? 312 LEU A HD12 1 
ATOM   4740 H HD13 . LEU A 1 312 ? 146.327 87.970  117.608 1.00 88.46  ? 312 LEU A HD13 1 
ATOM   4741 H HD21 . LEU A 1 312 ? 148.667 88.855  115.820 1.00 88.46  ? 312 LEU A HD21 1 
ATOM   4742 H HD22 . LEU A 1 312 ? 147.424 88.078  115.207 1.00 88.46  ? 312 LEU A HD22 1 
ATOM   4743 H HD23 . LEU A 1 312 ? 147.813 89.516  114.654 1.00 88.46  ? 312 LEU A HD23 1 
ATOM   4744 N N    . PRO A 1 313 ? 145.375 92.639  117.336 1.00 90.73  ? 313 PRO A N    1 
ATOM   4745 C CA   . PRO A 1 313 ? 145.617 94.053  117.048 1.00 90.73  ? 313 PRO A CA   1 
ATOM   4746 C C    . PRO A 1 313 ? 146.743 94.214  116.043 1.00 90.73  ? 313 PRO A C    1 
ATOM   4747 O O    . PRO A 1 313 ? 147.842 93.677  116.245 1.00 90.73  ? 313 PRO A O    1 
ATOM   4748 C CB   . PRO A 1 313 ? 146.002 94.628  118.416 1.00 90.73  ? 313 PRO A CB   1 
ATOM   4749 C CG   . PRO A 1 313 ? 146.663 93.492  119.107 1.00 90.73  ? 313 PRO A CG   1 
ATOM   4750 C CD   . PRO A 1 313 ? 145.988 92.232  118.614 1.00 90.73  ? 313 PRO A CD   1 
ATOM   4751 H HA   . PRO A 1 313 ? 144.806 94.481  116.738 1.00 90.73  ? 313 PRO A HA   1 
ATOM   4752 H HB2  . PRO A 1 313 ? 146.617 95.370  118.302 1.00 90.73  ? 313 PRO A HB2  1 
ATOM   4753 H HB3  . PRO A 1 313 ? 145.205 94.907  118.893 1.00 90.73  ? 313 PRO A HB3  1 
ATOM   4754 H HG2  . PRO A 1 313 ? 147.606 93.483  118.881 1.00 90.73  ? 313 PRO A HG2  1 
ATOM   4755 H HG3  . PRO A 1 313 ? 146.545 93.587  120.065 1.00 90.73  ? 313 PRO A HG3  1 
ATOM   4756 H HD2  . PRO A 1 313 ? 146.647 91.536  118.473 1.00 90.73  ? 313 PRO A HD2  1 
ATOM   4757 H HD3  . PRO A 1 313 ? 145.303 91.950  119.241 1.00 90.73  ? 313 PRO A HD3  1 
ATOM   4758 N N    . PRO A 1 314 ? 146.519 94.943  114.947 1.00 91.90  ? 314 PRO A N    1 
ATOM   4759 C CA   . PRO A 1 314 ? 147.603 95.166  113.979 1.00 91.90  ? 314 PRO A CA   1 
ATOM   4760 C C    . PRO A 1 314 ? 148.557 96.250  114.464 1.00 91.90  ? 314 PRO A C    1 
ATOM   4761 O O    . PRO A 1 314 ? 148.132 97.332  114.878 1.00 91.90  ? 314 PRO A O    1 
ATOM   4762 C CB   . PRO A 1 314 ? 146.864 95.593  112.706 1.00 91.90  ? 314 PRO A CB   1 
ATOM   4763 C CG   . PRO A 1 314 ? 145.603 96.204  113.199 1.00 91.90  ? 314 PRO A CG   1 
ATOM   4764 C CD   . PRO A 1 314 ? 145.233 95.478  114.463 1.00 91.90  ? 314 PRO A CD   1 
ATOM   4765 H HA   . PRO A 1 314 ? 148.094 94.345  113.815 1.00 91.90  ? 314 PRO A HA   1 
ATOM   4766 H HB2  . PRO A 1 314 ? 147.395 96.243  112.220 1.00 91.90  ? 314 PRO A HB2  1 
ATOM   4767 H HB3  . PRO A 1 314 ? 146.680 94.816  112.156 1.00 91.90  ? 314 PRO A HB3  1 
ATOM   4768 H HG2  . PRO A 1 314 ? 145.750 97.145  113.379 1.00 91.90  ? 314 PRO A HG2  1 
ATOM   4769 H HG3  . PRO A 1 314 ? 144.909 96.093  112.530 1.00 91.90  ? 314 PRO A HG3  1 
ATOM   4770 H HD2  . PRO A 1 314 ? 144.861 96.098  115.110 1.00 91.90  ? 314 PRO A HD2  1 
ATOM   4771 H HD3  . PRO A 1 314 ? 144.617 94.754  114.270 1.00 91.90  ? 314 PRO A HD3  1 
ATOM   4772 N N    . ALA A 1 315 ? 149.857 95.952  114.403 1.00 95.91  ? 315 ALA A N    1 
ATOM   4773 C CA   . ALA A 1 315 ? 150.868 96.880  114.897 1.00 95.91  ? 315 ALA A CA   1 
ATOM   4774 C C    . ALA A 1 315 ? 150.937 98.165  114.082 1.00 95.91  ? 315 ALA A C    1 
ATOM   4775 O O    . ALA A 1 315 ? 151.476 99.163  114.570 1.00 95.91  ? 315 ALA A O    1 
ATOM   4776 C CB   . ALA A 1 315 ? 152.238 96.201  114.903 1.00 95.91  ? 315 ALA A CB   1 
ATOM   4777 H H    . ALA A 1 315 ? 150.174 95.220  114.084 1.00 95.91  ? 315 ALA A H    1 
ATOM   4778 H HA   . ALA A 1 315 ? 150.652 97.120  115.811 1.00 95.91  ? 315 ALA A HA   1 
ATOM   4779 H HB1  . ALA A 1 315 ? 152.901 96.828  115.233 1.00 95.91  ? 315 ALA A HB1  1 
ATOM   4780 H HB2  . ALA A 1 315 ? 152.202 95.423  115.481 1.00 95.91  ? 315 ALA A HB2  1 
ATOM   4781 H HB3  . ALA A 1 315 ? 152.458 95.931  113.997 1.00 95.91  ? 315 ALA A HB3  1 
ATOM   4782 N N    . ASP A 1 316 ? 150.407 98.166  112.858 1.00 94.49  ? 316 ASP A N    1 
ATOM   4783 C CA   . ASP A 1 316 ? 150.496 99.340  111.999 1.00 94.49  ? 316 ASP A CA   1 
ATOM   4784 C C    . ASP A 1 316 ? 149.634 100.499 112.484 1.00 94.49  ? 316 ASP A C    1 
ATOM   4785 O O    . ASP A 1 316 ? 149.749 101.601 111.937 1.00 94.49  ? 316 ASP A O    1 
ATOM   4786 C CB   . ASP A 1 316 ? 150.098 98.971  110.569 1.00 94.49  ? 316 ASP A CB   1 
ATOM   4787 H H    . ASP A 1 316 ? 149.992 97.501  112.505 1.00 94.49  ? 316 ASP A H    1 
ATOM   4788 H HA   . ASP A 1 316 ? 151.417 99.645  111.983 1.00 94.49  ? 316 ASP A HA   1 
ATOM   4789 N N    . LEU A 1 317 ? 148.781 100.284 113.487 1.00 89.69  ? 317 LEU A N    1 
ATOM   4790 C CA   . LEU A 1 317 ? 147.903 101.350 113.955 1.00 89.69  ? 317 LEU A CA   1 
ATOM   4791 C C    . LEU A 1 317 ? 148.676 102.542 114.500 1.00 89.69  ? 317 LEU A C    1 
ATOM   4792 O O    . LEU A 1 317 ? 148.136 103.653 114.529 1.00 89.69  ? 317 LEU A O    1 
ATOM   4793 C CB   . LEU A 1 317 ? 146.961 100.815 115.032 1.00 89.69  ? 317 LEU A CB   1 
ATOM   4794 C CG   . LEU A 1 317 ? 145.930 99.795  114.552 1.00 89.69  ? 317 LEU A CG   1 
ATOM   4795 C CD1  . LEU A 1 317 ? 145.317 99.061  115.732 1.00 89.69  ? 317 LEU A CD1  1 
ATOM   4796 C CD2  . LEU A 1 317 ? 144.850 100.474 113.725 1.00 89.69  ? 317 LEU A CD2  1 
ATOM   4797 H H    . LEU A 1 317 ? 148.694 99.539  113.908 1.00 89.69  ? 317 LEU A H    1 
ATOM   4798 H HA   . LEU A 1 317 ? 147.364 101.661 113.211 1.00 89.69  ? 317 LEU A HA   1 
ATOM   4799 H HB2  . LEU A 1 317 ? 147.493 100.389 115.722 1.00 89.69  ? 317 LEU A HB2  1 
ATOM   4800 H HB3  . LEU A 1 317 ? 146.475 101.563 115.413 1.00 89.69  ? 317 LEU A HB3  1 
ATOM   4801 H HG   . LEU A 1 317 ? 146.375 99.144  113.988 1.00 89.69  ? 317 LEU A HG   1 
ATOM   4802 H HD11 . LEU A 1 317 ? 144.611 98.479  115.409 1.00 89.69  ? 317 LEU A HD11 1 
ATOM   4803 H HD12 . LEU A 1 317 ? 146.005 98.536  116.168 1.00 89.69  ? 317 LEU A HD12 1 
ATOM   4804 H HD13 . LEU A 1 317 ? 144.952 99.711  116.352 1.00 89.69  ? 317 LEU A HD13 1 
ATOM   4805 H HD21 . LEU A 1 317 ? 144.203 99.809  113.444 1.00 89.69  ? 317 LEU A HD21 1 
ATOM   4806 H HD22 . LEU A 1 317 ? 144.415 101.150 114.269 1.00 89.69  ? 317 LEU A HD22 1 
ATOM   4807 H HD23 . LEU A 1 317 ? 145.257 100.887 112.948 1.00 89.69  ? 317 LEU A HD23 1 
ATOM   4808 N N    . LYS A 1 318 ? 149.925 102.343 114.926 1.00 93.29  ? 318 LYS A N    1 
ATOM   4809 C CA   . LYS A 1 318 ? 150.682 103.439 115.519 1.00 93.29  ? 318 LYS A CA   1 
ATOM   4810 C C    . LYS A 1 318 ? 150.800 104.620 114.565 1.00 93.29  ? 318 LYS A C    1 
ATOM   4811 O O    . LYS A 1 318 ? 150.926 105.766 115.011 1.00 93.29  ? 318 LYS A O    1 
ATOM   4812 C CB   . LYS A 1 318 ? 152.072 102.954 115.933 1.00 93.29  ? 318 LYS A CB   1 
ATOM   4813 C CG   . LYS A 1 318 ? 152.069 101.730 116.845 1.00 93.29  ? 318 LYS A CG   1 
ATOM   4814 C CD   . LYS A 1 318 ? 151.196 101.922 118.081 1.00 93.29  ? 318 LYS A CD   1 
ATOM   4815 C CE   . LYS A 1 318 ? 151.665 103.091 118.936 1.00 93.29  ? 318 LYS A CE   1 
ATOM   4816 N NZ   . LYS A 1 318 ? 150.835 103.250 120.162 1.00 93.29  ? 318 LYS A NZ   1 
ATOM   4817 H H    . LYS A 1 318 ? 150.347 101.595 114.882 1.00 93.29  ? 318 LYS A H    1 
ATOM   4818 H HA   . LYS A 1 318 ? 150.221 103.749 116.313 1.00 93.29  ? 318 LYS A HA   1 
ATOM   4819 H HB2  . LYS A 1 318 ? 152.569 102.721 115.133 1.00 93.29  ? 318 LYS A HB2  1 
ATOM   4820 H HB3  . LYS A 1 318 ? 152.528 103.672 116.399 1.00 93.29  ? 318 LYS A HB3  1 
ATOM   4821 H HG2  . LYS A 1 318 ? 151.729 100.967 116.352 1.00 93.29  ? 318 LYS A HG2  1 
ATOM   4822 H HG3  . LYS A 1 318 ? 152.976 101.556 117.142 1.00 93.29  ? 318 LYS A HG3  1 
ATOM   4823 H HD2  . LYS A 1 318 ? 150.280 102.089 117.811 1.00 93.29  ? 318 LYS A HD2  1 
ATOM   4824 H HD3  . LYS A 1 318 ? 151.238 101.119 118.624 1.00 93.29  ? 318 LYS A HD3  1 
ATOM   4825 H HE2  . LYS A 1 318 ? 152.583 102.939 119.209 1.00 93.29  ? 318 LYS A HE2  1 
ATOM   4826 H HE3  . LYS A 1 318 ? 151.599 103.912 118.423 1.00 93.29  ? 318 LYS A HE3  1 
ATOM   4827 H HZ1  . LYS A 1 318 ? 151.148 103.921 120.656 1.00 93.29  ? 318 LYS A HZ1  1 
ATOM   4828 H HZ2  . LYS A 1 318 ? 149.992 103.426 119.938 1.00 93.29  ? 318 LYS A HZ2  1 
ATOM   4829 H HZ3  . LYS A 1 318 ? 150.856 102.502 120.643 1.00 93.29  ? 318 LYS A HZ3  1 
ATOM   4830 N N    . MET A 1 319 ? 150.761 104.366 113.257 1.00 90.11  ? 319 MET A N    1 
ATOM   4831 C CA   . MET A 1 319 ? 150.869 105.410 112.246 1.00 90.11  ? 319 MET A CA   1 
ATOM   4832 C C    . MET A 1 319 ? 149.542 105.648 111.530 1.00 90.11  ? 319 MET A C    1 
ATOM   4833 O O    . MET A 1 319 ? 149.523 106.062 110.369 1.00 90.11  ? 319 MET A O    1 
ATOM   4834 C CB   . MET A 1 319 ? 151.958 105.056 111.235 1.00 90.11  ? 319 MET A CB   1 
ATOM   4835 H H    . MET A 1 319 ? 150.671 103.578 112.926 1.00 90.11  ? 319 MET A H    1 
ATOM   4836 H HA   . MET A 1 319 ? 151.134 106.236 112.679 1.00 90.11  ? 319 MET A HA   1 
ATOM   4837 N N    . LEU A 1 320 ? 148.426 105.393 112.209 1.00 86.76  ? 320 LEU A N    1 
ATOM   4838 C CA   . LEU A 1 320 ? 147.119 105.567 111.589 1.00 86.76  ? 320 LEU A CA   1 
ATOM   4839 C C    . LEU A 1 320 ? 146.853 107.041 111.312 1.00 86.76  ? 320 LEU A C    1 
ATOM   4840 O O    . LEU A 1 320 ? 147.056 107.897 112.179 1.00 86.76  ? 320 LEU A O    1 
ATOM   4841 C CB   . LEU A 1 320 ? 146.025 104.993 112.487 1.00 86.76  ? 320 LEU A CB   1 
ATOM   4842 C CG   . LEU A 1 320 ? 144.587 105.228 112.017 1.00 86.76  ? 320 LEU A CG   1 
ATOM   4843 C CD1  . LEU A 1 320 ? 144.371 104.672 110.619 1.00 86.76  ? 320 LEU A CD1  1 
ATOM   4844 C CD2  . LEU A 1 320 ? 143.603 104.612 112.994 1.00 86.76  ? 320 LEU A CD2  1 
ATOM   4845 H H    . LEU A 1 320 ? 148.400 105.119 113.024 1.00 86.76  ? 320 LEU A H    1 
ATOM   4846 H HA   . LEU A 1 320 ? 147.102 105.090 110.745 1.00 86.76  ? 320 LEU A HA   1 
ATOM   4847 H HB2  . LEU A 1 320 ? 146.155 104.034 112.554 1.00 86.76  ? 320 LEU A HB2  1 
ATOM   4848 H HB3  . LEU A 1 320 ? 146.112 105.392 113.367 1.00 86.76  ? 320 LEU A HB3  1 
ATOM   4849 H HG   . LEU A 1 320 ? 144.415 106.182 111.989 1.00 86.76  ? 320 LEU A HG   1 
ATOM   4850 H HD11 . LEU A 1 320 ? 143.437 104.781 110.380 1.00 86.76  ? 320 LEU A HD11 1 
ATOM   4851 H HD12 . LEU A 1 320 ? 144.930 105.157 109.993 1.00 86.76  ? 320 LEU A HD12 1 
ATOM   4852 H HD13 . LEU A 1 320 ? 144.606 103.731 110.614 1.00 86.76  ? 320 LEU A HD13 1 
ATOM   4853 H HD21 . LEU A 1 320 ? 142.700 104.811 112.699 1.00 86.76  ? 320 LEU A HD21 1 
ATOM   4854 H HD22 . LEU A 1 320 ? 143.740 103.652 113.017 1.00 86.76  ? 320 LEU A HD22 1 
ATOM   4855 H HD23 . LEU A 1 320 ? 143.754 104.991 113.874 1.00 86.76  ? 320 LEU A HD23 1 
ATOM   4856 N N    . SER A 1 321 ? 146.394 107.333 110.101 1.00 84.91  ? 321 SER A N    1 
ATOM   4857 C CA   . SER A 1 321 ? 146.053 108.690 109.686 1.00 84.91  ? 321 SER A CA   1 
ATOM   4858 C C    . SER A 1 321 ? 145.367 108.592 108.329 1.00 84.91  ? 321 SER A C    1 
ATOM   4859 O O    . SER A 1 321 ? 145.251 107.508 107.748 1.00 84.91  ? 321 SER A O    1 
ATOM   4860 C CB   . SER A 1 321 ? 147.291 109.587 109.627 1.00 84.91  ? 321 SER A CB   1 
ATOM   4861 O OG   . SER A 1 321 ? 148.227 109.103 108.680 1.00 84.91  ? 321 SER A OG   1 
ATOM   4862 H H    . SER A 1 321 ? 146.269 106.747 109.485 1.00 84.91  ? 321 SER A H    1 
ATOM   4863 H HA   . SER A 1 321 ? 145.429 109.076 110.319 1.00 84.91  ? 321 SER A HA   1 
ATOM   4864 H HB2  . SER A 1 321 ? 147.018 110.483 109.372 1.00 84.91  ? 321 SER A HB2  1 
ATOM   4865 H HB3  . SER A 1 321 ? 147.710 109.606 110.502 1.00 84.91  ? 321 SER A HB3  1 
ATOM   4866 H HG   . SER A 1 321 ? 148.874 109.635 108.618 1.00 84.91  ? 321 SER A HG   1 
ATOM   4867 N N    . LEU A 1 322 ? 144.912 109.735 107.826 1.00 81.15  ? 322 LEU A N    1 
ATOM   4868 C CA   . LEU A 1 322 ? 144.310 109.775 106.503 1.00 81.15  ? 322 LEU A CA   1 
ATOM   4869 C C    . LEU A 1 322 ? 145.360 109.492 105.433 1.00 81.15  ? 322 LEU A C    1 
ATOM   4870 O O    . LEU A 1 322 ? 146.568 109.583 105.668 1.00 81.15  ? 322 LEU A O    1 
ATOM   4871 C CB   . LEU A 1 322 ? 143.657 111.133 106.249 1.00 81.15  ? 322 LEU A CB   1 
ATOM   4872 C CG   . LEU A 1 322 ? 142.392 111.428 107.056 1.00 81.15  ? 322 LEU A CG   1 
ATOM   4873 C CD1  . LEU A 1 322 ? 141.983 112.883 106.889 1.00 81.15  ? 322 LEU A CD1  1 
ATOM   4874 C CD2  . LEU A 1 322 ? 141.260 110.504 106.638 1.00 81.15  ? 322 LEU A CD2  1 
ATOM   4875 H H    . LEU A 1 322 ? 144.941 110.495 108.228 1.00 81.15  ? 322 LEU A H    1 
ATOM   4876 H HA   . LEU A 1 322 ? 143.627 109.090 106.442 1.00 81.15  ? 322 LEU A HA   1 
ATOM   4877 H HB2  . LEU A 1 322 ? 144.303 111.826 106.460 1.00 81.15  ? 322 LEU A HB2  1 
ATOM   4878 H HB3  . LEU A 1 322 ? 143.422 111.188 105.310 1.00 81.15  ? 322 LEU A HB3  1 
ATOM   4879 H HG   . LEU A 1 322 ? 142.574 111.274 107.996 1.00 81.15  ? 322 LEU A HG   1 
ATOM   4880 H HD11 . LEU A 1 322 ? 141.165 113.040 107.387 1.00 81.15  ? 322 LEU A HD11 1 
ATOM   4881 H HD12 . LEU A 1 322 ? 142.692 113.451 107.230 1.00 81.15  ? 322 LEU A HD12 1 
ATOM   4882 H HD13 . LEU A 1 322 ? 141.838 113.064 105.948 1.00 81.15  ? 322 LEU A HD13 1 
ATOM   4883 H HD21 . LEU A 1 322 ? 140.454 110.758 107.114 1.00 81.15  ? 322 LEU A HD21 1 
ATOM   4884 H HD22 . LEU A 1 322 ? 141.121 110.590 105.682 1.00 81.15  ? 322 LEU A HD22 1 
ATOM   4885 H HD23 . LEU A 1 322 ? 141.498 109.590 106.856 1.00 81.15  ? 322 LEU A HD23 1 
ATOM   4886 N N    . LYS A 1 323 ? 144.880 109.134 104.241 1.00 89.32  ? 323 LYS A N    1 
ATOM   4887 C CA   . LYS A 1 323 ? 145.785 108.815 103.141 1.00 89.32  ? 323 LYS A CA   1 
ATOM   4888 C C    . LYS A 1 323 ? 146.787 109.940 102.912 1.00 89.32  ? 323 LYS A C    1 
ATOM   4889 O O    . LYS A 1 323 ? 147.998 109.706 102.837 1.00 89.32  ? 323 LYS A O    1 
ATOM   4890 C CB   . LYS A 1 323 ? 144.982 108.544 101.869 1.00 89.32  ? 323 LYS A CB   1 
ATOM   4891 H H    . LYS A 1 323 ? 144.044 109.068 104.047 1.00 89.32  ? 323 LYS A H    1 
ATOM   4892 H HA   . LYS A 1 323 ? 146.281 108.011 103.361 1.00 89.32  ? 323 LYS A HA   1 
ATOM   4893 N N    . GLU A 1 324 ? 146.297 111.170 102.802 1.00 92.30  ? 324 GLU A N    1 
ATOM   4894 C CA   . GLU A 1 324 ? 147.141 112.343 102.639 1.00 92.30  ? 324 GLU A CA   1 
ATOM   4895 C C    . GLU A 1 324 ? 147.119 113.184 103.910 1.00 92.30  ? 324 GLU A C    1 
ATOM   4896 O O    . GLU A 1 324 ? 146.103 113.266 104.604 1.00 92.30  ? 324 GLU A O    1 
ATOM   4897 C CB   . GLU A 1 324 ? 146.679 113.188 101.450 1.00 92.30  ? 324 GLU A CB   1 
ATOM   4898 H H    . GLU A 1 324 ? 145.457 111.354 102.817 1.00 92.30  ? 324 GLU A H    1 
ATOM   4899 H HA   . GLU A 1 324 ? 148.055 112.064 102.476 1.00 92.30  ? 324 GLU A HA   1 
ATOM   4900 N N    . ASP A 1 325 ? 148.256 113.810 104.209 1.00 93.33  ? 325 ASP A N    1 
ATOM   4901 C CA   . ASP A 1 325 ? 148.346 114.685 105.370 1.00 93.33  ? 325 ASP A CA   1 
ATOM   4902 C C    . ASP A 1 325 ? 147.356 115.833 105.224 1.00 93.33  ? 325 ASP A C    1 
ATOM   4903 O O    . ASP A 1 325 ? 147.537 116.714 104.378 1.00 93.33  ? 325 ASP A O    1 
ATOM   4904 C CB   . ASP A 1 325 ? 149.770 115.219 105.536 1.00 93.33  ? 325 ASP A CB   1 
ATOM   4905 H H    . ASP A 1 325 ? 148.985 113.743 103.758 1.00 93.33  ? 325 ASP A H    1 
ATOM   4906 H HA   . ASP A 1 325 ? 148.115 114.183 106.168 1.00 93.33  ? 325 ASP A HA   1 
ATOM   4907 N N    . SER A 1 326 ? 146.309 115.830 106.044 1.00 88.06  ? 326 SER A N    1 
ATOM   4908 C CA   . SER A 1 326 ? 145.250 116.818 105.932 1.00 88.06  ? 326 SER A CA   1 
ATOM   4909 C C    . SER A 1 326 ? 145.634 118.094 106.678 1.00 88.06  ? 326 SER A C    1 
ATOM   4910 O O    . SER A 1 326 ? 146.700 118.197 107.290 1.00 88.06  ? 326 SER A O    1 
ATOM   4911 C CB   . SER A 1 326 ? 143.938 116.247 106.464 1.00 88.06  ? 326 SER A CB   1 
ATOM   4912 O OG   . SER A 1 326 ? 144.068 115.853 107.819 1.00 88.06  ? 326 SER A OG   1 
ATOM   4913 H H    . SER A 1 326 ? 146.192 115.261 106.678 1.00 88.06  ? 326 SER A H    1 
ATOM   4914 H HA   . SER A 1 326 ? 145.123 117.043 104.997 1.00 88.06  ? 326 SER A HA   1 
ATOM   4915 H HB2  . SER A 1 326 ? 143.248 116.925 106.398 1.00 88.06  ? 326 SER A HB2  1 
ATOM   4916 H HB3  . SER A 1 326 ? 143.694 115.473 105.934 1.00 88.06  ? 326 SER A HB3  1 
ATOM   4917 H HG   . SER A 1 326 ? 143.338 115.550 108.103 1.00 88.06  ? 326 SER A HG   1 
ATOM   4918 N N    . THR A 1 327 ? 144.749 119.083 106.623 1.00 88.50  ? 327 THR A N    1 
ATOM   4919 C CA   . THR A 1 327 ? 144.958 120.344 107.314 1.00 88.50  ? 327 THR A CA   1 
ATOM   4920 C C    . THR A 1 327 ? 144.492 120.234 108.761 1.00 88.50  ? 327 THR A C    1 
ATOM   4921 O O    . THR A 1 327 ? 143.723 119.343 109.129 1.00 88.50  ? 327 THR A O    1 
ATOM   4922 C CB   . THR A 1 327 ? 144.212 121.478 106.610 1.00 88.50  ? 327 THR A CB   1 
ATOM   4923 H H    . THR A 1 327 ? 144.009 119.044 106.186 1.00 88.50  ? 327 THR A H    1 
ATOM   4924 H HA   . THR A 1 327 ? 145.904 120.556 107.314 1.00 88.50  ? 327 THR A HA   1 
ATOM   4925 N N    . GLU A 1 328 ? 144.970 121.167 109.587 1.00 82.19  ? 328 GLU A N    1 
ATOM   4926 C CA   . GLU A 1 328 ? 144.645 121.132 111.008 1.00 82.19  ? 328 GLU A CA   1 
ATOM   4927 C C    . GLU A 1 328 ? 143.138 121.186 111.228 1.00 82.19  ? 328 GLU A C    1 
ATOM   4928 O O    . GLU A 1 328 ? 142.582 120.399 112.003 1.00 82.19  ? 328 GLU A O    1 
ATOM   4929 C CB   . GLU A 1 328 ? 145.336 122.290 111.729 1.00 82.19  ? 328 GLU A CB   1 
ATOM   4930 H H    . GLU A 1 328 ? 145.480 121.818 109.351 1.00 82.19  ? 328 GLU A H    1 
ATOM   4931 H HA   . GLU A 1 328 ? 144.977 120.304 111.386 1.00 82.19  ? 328 GLU A HA   1 
ATOM   4932 N N    . LYS A 1 329 ? 142.459 122.105 110.549 1.00 78.73  ? 329 LYS A N    1 
ATOM   4933 C CA   . LYS A 1 329 ? 141.029 122.311 110.719 1.00 78.73  ? 329 LYS A CA   1 
ATOM   4934 C C    . LYS A 1 329 ? 140.265 121.731 109.536 1.00 78.73  ? 329 LYS A C    1 
ATOM   4935 O O    . LYS A 1 329 ? 140.689 121.860 108.384 1.00 78.73  ? 329 LYS A O    1 
ATOM   4936 C CB   . LYS A 1 329 ? 140.709 123.800 110.863 1.00 78.73  ? 329 LYS A CB   1 
ATOM   4937 H H    . LYS A 1 329 ? 142.816 122.632 109.970 1.00 78.73  ? 329 LYS A H    1 
ATOM   4938 H HA   . LYS A 1 329 ? 140.731 121.859 111.524 1.00 78.73  ? 329 LYS A HA   1 
ATOM   4939 N N    . LEU A 1 330 ? 139.138 121.086 109.832 1.00 69.72  ? 330 LEU A N    1 
ATOM   4940 C CA   . LEU A 1 330 ? 138.253 120.528 108.815 1.00 69.72  ? 330 LEU A CA   1 
ATOM   4941 C C    . LEU A 1 330 ? 136.799 120.789 109.191 1.00 69.72  ? 330 LEU A C    1 
ATOM   4942 O O    . LEU A 1 330 ? 135.946 119.899 109.113 1.00 69.72  ? 330 LEU A O    1 
ATOM   4943 C CB   . LEU A 1 330 ? 138.513 119.033 108.627 1.00 69.72  ? 330 LEU A CB   1 
ATOM   4944 C CG   . LEU A 1 330 ? 137.882 118.363 107.405 1.00 69.72  ? 330 LEU A CG   1 
ATOM   4945 C CD1  . LEU A 1 330 ? 138.328 119.041 106.122 1.00 69.72  ? 330 LEU A CD1  1 
ATOM   4946 C CD2  . LEU A 1 330 ? 138.236 116.888 107.375 1.00 69.72  ? 330 LEU A CD2  1 
ATOM   4947 H H    . LEU A 1 330 ? 138.861 120.956 110.635 1.00 69.72  ? 330 LEU A H    1 
ATOM   4948 H HA   . LEU A 1 330 ? 138.427 120.974 107.972 1.00 69.72  ? 330 LEU A HA   1 
ATOM   4949 H HB2  . LEU A 1 330 ? 139.472 118.902 108.560 1.00 69.72  ? 330 LEU A HB2  1 
ATOM   4950 H HB3  . LEU A 1 330 ? 138.182 118.569 109.412 1.00 69.72  ? 330 LEU A HB3  1 
ATOM   4951 H HG   . LEU A 1 330 ? 136.917 118.437 107.464 1.00 69.72  ? 330 LEU A HG   1 
ATOM   4952 H HD11 . LEU A 1 330 ? 138.080 118.483 105.369 1.00 69.72  ? 330 LEU A HD11 1 
ATOM   4953 H HD12 . LEU A 1 330 ? 137.890 119.904 106.052 1.00 69.72  ? 330 LEU A HD12 1 
ATOM   4954 H HD13 . LEU A 1 330 ? 139.290 119.157 106.145 1.00 69.72  ? 330 LEU A HD13 1 
ATOM   4955 H HD21 . LEU A 1 330 ? 137.828 116.482 106.594 1.00 69.72  ? 330 LEU A HD21 1 
ATOM   4956 H HD22 . LEU A 1 330 ? 139.201 116.796 107.331 1.00 69.72  ? 330 LEU A HD22 1 
ATOM   4957 H HD23 . LEU A 1 330 ? 137.900 116.467 108.181 1.00 69.72  ? 330 LEU A HD23 1 
ATOM   4958 N N    . SER A 1 331 ? 136.504 122.016 109.602 1.00 66.16  ? 331 SER A N    1 
ATOM   4959 C CA   . SER A 1 331 ? 135.199 122.332 110.168 1.00 66.16  ? 331 SER A CA   1 
ATOM   4960 C C    . SER A 1 331 ? 134.093 122.135 109.134 1.00 66.16  ? 331 SER A C    1 
ATOM   4961 O O    . SER A 1 331 ? 134.267 122.514 107.968 1.00 66.16  ? 331 SER A O    1 
ATOM   4962 C CB   . SER A 1 331 ? 135.183 123.772 110.674 1.00 66.16  ? 331 SER A CB   1 
ATOM   4963 O OG   . SER A 1 331 ? 135.340 124.685 109.602 1.00 66.16  ? 331 SER A OG   1 
ATOM   4964 H H    . SER A 1 331 ? 137.043 122.685 109.566 1.00 66.16  ? 331 SER A H    1 
ATOM   4965 H HA   . SER A 1 331 ? 135.040 121.747 110.923 1.00 66.16  ? 331 SER A HA   1 
ATOM   4966 H HB2  . SER A 1 331 ? 134.336 123.944 111.114 1.00 66.16  ? 331 SER A HB2  1 
ATOM   4967 H HB3  . SER A 1 331 ? 135.913 123.895 111.302 1.00 66.16  ? 331 SER A HB3  1 
ATOM   4968 H HG   . SER A 1 331 ? 136.050 124.518 109.185 1.00 66.16  ? 331 SER A HG   1 
ATOM   4969 N N    . PRO A 1 332 ? 132.953 121.554 109.511 1.00 61.93  ? 332 PRO A N    1 
ATOM   4970 C CA   . PRO A 1 332 ? 131.813 121.494 108.588 1.00 61.93  ? 332 PRO A CA   1 
ATOM   4971 C C    . PRO A 1 332 ? 131.058 122.812 108.541 1.00 61.93  ? 332 PRO A C    1 
ATOM   4972 O O    . PRO A 1 332 ? 130.818 123.452 109.567 1.00 61.93  ? 332 PRO A O    1 
ATOM   4973 C CB   . PRO A 1 332 ? 130.943 120.382 109.182 1.00 61.93  ? 332 PRO A CB   1 
ATOM   4974 C CG   . PRO A 1 332 ? 131.216 120.452 110.639 1.00 61.93  ? 332 PRO A CG   1 
ATOM   4975 C CD   . PRO A 1 332 ? 132.663 120.858 110.778 1.00 61.93  ? 332 PRO A CD   1 
ATOM   4976 H HA   . PRO A 1 332 ? 132.104 121.246 107.697 1.00 61.93  ? 332 PRO A HA   1 
ATOM   4977 H HB2  . PRO A 1 332 ? 130.008 120.558 108.995 1.00 61.93  ? 332 PRO A HB2  1 
ATOM   4978 H HB3  . PRO A 1 332 ? 131.215 119.523 108.821 1.00 61.93  ? 332 PRO A HB3  1 
ATOM   4979 H HG2  . PRO A 1 332 ? 130.635 121.114 111.046 1.00 61.93  ? 332 PRO A HG2  1 
ATOM   4980 H HG3  . PRO A 1 332 ? 131.069 119.580 111.037 1.00 61.93  ? 332 PRO A HG3  1 
ATOM   4981 H HD2  . PRO A 1 332 ? 132.773 121.463 111.528 1.00 61.93  ? 332 PRO A HD2  1 
ATOM   4982 H HD3  . PRO A 1 332 ? 133.227 120.074 110.868 1.00 61.93  ? 332 PRO A HD3  1 
ATOM   4983 N N    . SER A 1 333 ? 130.678 123.215 107.331 1.00 60.23  ? 333 SER A N    1 
ATOM   4984 C CA   . SER A 1 333 ? 129.957 124.464 107.138 1.00 60.23  ? 333 SER A CA   1 
ATOM   4985 C C    . SER A 1 333 ? 129.034 124.340 105.936 1.00 60.23  ? 333 SER A C    1 
ATOM   4986 O O    . SER A 1 333 ? 129.301 123.574 105.006 1.00 60.23  ? 333 SER A O    1 
ATOM   4987 C CB   . SER A 1 333 ? 130.920 125.639 106.942 1.00 60.23  ? 333 SER A CB   1 
ATOM   4988 O OG   . SER A 1 333 ? 130.217 126.823 106.610 1.00 60.23  ? 333 SER A OG   1 
ATOM   4989 H H    . SER A 1 333 ? 130.828 122.780 106.604 1.00 60.23  ? 333 SER A H    1 
ATOM   4990 H HA   . SER A 1 333 ? 129.413 124.643 107.921 1.00 60.23  ? 333 SER A HA   1 
ATOM   4991 H HB2  . SER A 1 333 ? 131.410 125.785 107.766 1.00 60.23  ? 333 SER A HB2  1 
ATOM   4992 H HB3  . SER A 1 333 ? 131.537 125.425 106.225 1.00 60.23  ? 333 SER A HB3  1 
ATOM   4993 H HG   . SER A 1 333 ? 130.758 127.455 106.494 1.00 60.23  ? 333 SER A HG   1 
ATOM   4994 N N    . PHE A 1 334 ? 127.939 125.106 105.965 1.00 56.36  ? 334 PHE A N    1 
ATOM   4995 C CA   . PHE A 1 334 ? 127.034 125.141 104.821 1.00 56.36  ? 334 PHE A CA   1 
ATOM   4996 C C    . PHE A 1 334 ? 127.740 125.636 103.568 1.00 56.36  ? 334 PHE A C    1 
ATOM   4997 O O    . PHE A 1 334 ? 127.434 125.178 102.462 1.00 56.36  ? 334 PHE A O    1 
ATOM   4998 C CB   . PHE A 1 334 ? 125.832 126.034 105.122 1.00 56.36  ? 334 PHE A CB   1 
ATOM   4999 C CG   . PHE A 1 334 ? 124.735 125.346 105.877 1.00 56.36  ? 334 PHE A CG   1 
ATOM   5000 C CD1  . PHE A 1 334 ? 123.806 124.566 105.215 1.00 56.36  ? 334 PHE A CD1  1 
ATOM   5001 C CD2  . PHE A 1 334 ? 124.620 125.493 107.247 1.00 56.36  ? 334 PHE A CD2  1 
ATOM   5002 C CE1  . PHE A 1 334 ? 122.791 123.937 105.906 1.00 56.36  ? 334 PHE A CE1  1 
ATOM   5003 C CE2  . PHE A 1 334 ? 123.607 124.866 107.942 1.00 56.36  ? 334 PHE A CE2  1 
ATOM   5004 C CZ   . PHE A 1 334 ? 122.692 124.088 107.270 1.00 56.36  ? 334 PHE A CZ   1 
ATOM   5005 H H    . PHE A 1 334 ? 127.705 125.606 106.624 1.00 56.36  ? 334 PHE A H    1 
ATOM   5006 H HA   . PHE A 1 334 ? 126.708 124.244 104.649 1.00 56.36  ? 334 PHE A HA   1 
ATOM   5007 H HB2  . PHE A 1 334 ? 126.129 126.789 105.653 1.00 56.36  ? 334 PHE A HB2  1 
ATOM   5008 H HB3  . PHE A 1 334 ? 125.460 126.350 104.283 1.00 56.36  ? 334 PHE A HB3  1 
ATOM   5009 H HD1  . PHE A 1 334 ? 123.868 124.460 104.293 1.00 56.36  ? 334 PHE A HD1  1 
ATOM   5010 H HD2  . PHE A 1 334 ? 125.236 126.017 107.706 1.00 56.36  ? 334 PHE A HD2  1 
ATOM   5011 H HE1  . PHE A 1 334 ? 122.174 123.411 105.450 1.00 56.36  ? 334 PHE A HE1  1 
ATOM   5012 H HE2  . PHE A 1 334 ? 123.542 124.969 108.864 1.00 56.36  ? 334 PHE A HE2  1 
ATOM   5013 H HZ   . PHE A 1 334 ? 122.008 123.664 107.737 1.00 56.36  ? 334 PHE A HZ   1 
ATOM   5014 N N    . ALA A 1 335 ? 128.685 126.566 103.718 1.00 62.01  ? 335 ALA A N    1 
ATOM   5015 C CA   . ALA A 1 335 ? 129.361 127.128 102.554 1.00 62.01  ? 335 ALA A CA   1 
ATOM   5016 C C    . ALA A 1 335 ? 130.104 126.052 101.773 1.00 62.01  ? 335 ALA A C    1 
ATOM   5017 O O    . ALA A 1 335 ? 130.087 126.047 100.537 1.00 62.01  ? 335 ALA A O    1 
ATOM   5018 C CB   . ALA A 1 335 ? 130.322 128.232 102.992 1.00 62.01  ? 335 ALA A CB   1 
ATOM   5019 H H    . ALA A 1 335 ? 128.948 126.882 104.473 1.00 62.01  ? 335 ALA A H    1 
ATOM   5020 H HA   . ALA A 1 335 ? 128.699 127.522 101.964 1.00 62.01  ? 335 ALA A HA   1 
ATOM   5021 H HB1  . ALA A 1 335 ? 130.756 128.602 102.207 1.00 62.01  ? 335 ALA A HB1  1 
ATOM   5022 H HB2  . ALA A 1 335 ? 129.820 128.923 103.451 1.00 62.01  ? 335 ALA A HB2  1 
ATOM   5023 H HB3  . ALA A 1 335 ? 130.986 127.853 103.590 1.00 62.01  ? 335 ALA A HB3  1 
ATOM   5024 N N    . ASP A 1 336 ? 130.759 125.127 102.477 1.00 62.22  ? 336 ASP A N    1 
ATOM   5025 C CA   . ASP A 1 336 ? 131.519 124.070 101.825 1.00 62.22  ? 336 ASP A CA   1 
ATOM   5026 C C    . ASP A 1 336 ? 130.636 123.101 101.050 1.00 62.22  ? 336 ASP A C    1 
ATOM   5027 O O    . ASP A 1 336 ? 131.160 122.315 100.254 1.00 62.22  ? 336 ASP A O    1 
ATOM   5028 C CB   . ASP A 1 336 ? 132.331 123.302 102.870 1.00 62.22  ? 336 ASP A CB   1 
ATOM   5029 C CG   . ASP A 1 336 ? 133.350 122.368 102.250 1.00 62.22  ? 336 ASP A CG   1 
ATOM   5030 O OD1  . ASP A 1 336 ? 134.418 122.853 101.820 1.00 62.22  ? 336 ASP A OD1  1 
ATOM   5031 O OD2  . ASP A 1 336 ? 133.085 121.150 102.193 1.00 62.22  ? 336 ASP A OD2  1 
ATOM   5032 H H    . ASP A 1 336 ? 130.776 125.093 103.337 1.00 62.22  ? 336 ASP A H    1 
ATOM   5033 H HA   . ASP A 1 336 ? 132.142 124.471 101.199 1.00 62.22  ? 336 ASP A HA   1 
ATOM   5034 H HB2  . ASP A 1 336 ? 132.806 123.935 103.431 1.00 62.22  ? 336 ASP A HB2  1 
ATOM   5035 H HB3  . ASP A 1 336 ? 131.727 122.768 103.410 1.00 62.22  ? 336 ASP A HB3  1 
ATOM   5036 N N    . LEU A 1 337 ? 129.319 123.134 101.263 1.00 58.61  ? 337 LEU A N    1 
ATOM   5037 C CA   . LEU A 1 337 ? 128.437 122.180 100.601 1.00 58.61  ? 337 LEU A CA   1 
ATOM   5038 C C    . LEU A 1 337 ? 128.219 122.525 99.133  1.00 58.61  ? 337 LEU A C    1 
ATOM   5039 O O    . LEU A 1 337 ? 127.955 121.628 98.324  1.00 58.61  ? 337 LEU A O    1 
ATOM   5040 C CB   . LEU A 1 337 ? 127.096 122.119 101.332 1.00 58.61  ? 337 LEU A CB   1 
ATOM   5041 C CG   . LEU A 1 337 ? 126.088 121.095 100.808 1.00 58.61  ? 337 LEU A CG   1 
ATOM   5042 C CD1  . LEU A 1 337 ? 126.663 119.692 100.874 1.00 58.61  ? 337 LEU A CD1  1 
ATOM   5043 C CD2  . LEU A 1 337 ? 124.791 121.173 101.592 1.00 58.61  ? 337 LEU A CD2  1 
ATOM   5044 H H    . LEU A 1 337 ? 128.918 123.693 101.779 1.00 58.61  ? 337 LEU A H    1 
ATOM   5045 H HA   . LEU A 1 337 ? 128.843 121.301 100.643 1.00 58.61  ? 337 LEU A HA   1 
ATOM   5046 H HB2  . LEU A 1 337 ? 127.266 121.905 102.263 1.00 58.61  ? 337 LEU A HB2  1 
ATOM   5047 H HB3  . LEU A 1 337 ? 126.677 122.992 101.274 1.00 58.61  ? 337 LEU A HB3  1 
ATOM   5048 H HG   . LEU A 1 337 ? 125.889 121.292 99.879  1.00 58.61  ? 337 LEU A HG   1 
ATOM   5049 H HD11 . LEU A 1 337 ? 125.955 119.056 100.689 1.00 58.61  ? 337 LEU A HD11 1 
ATOM   5050 H HD12 . LEU A 1 337 ? 127.367 119.605 100.212 1.00 58.61  ? 337 LEU A HD12 1 
ATOM   5051 H HD13 . LEU A 1 337 ? 127.021 119.538 101.762 1.00 58.61  ? 337 LEU A HD13 1 
ATOM   5052 H HD21 . LEU A 1 337 ? 124.167 120.522 101.234 1.00 58.61  ? 337 LEU A HD21 1 
ATOM   5053 H HD22 . LEU A 1 337 ? 124.973 120.979 102.524 1.00 58.61  ? 337 LEU A HD22 1 
ATOM   5054 H HD23 . LEU A 1 337 ? 124.423 122.066 101.504 1.00 58.61  ? 337 LEU A HD23 1 
ATOM   5055 N N    . PHE A 1 338 ? 128.313 123.803 98.769  1.00 58.74  ? 338 PHE A N    1 
ATOM   5056 C CA   . PHE A 1 338 ? 127.981 124.266 97.426  1.00 58.74  ? 338 PHE A CA   1 
ATOM   5057 C C    . PHE A 1 338 ? 129.189 124.844 96.690  1.00 58.74  ? 338 PHE A C    1 
ATOM   5058 O O    . PHE A 1 338 ? 129.049 125.778 95.898  1.00 58.74  ? 338 PHE A O    1 
ATOM   5059 C CB   . PHE A 1 338 ? 126.856 125.296 97.497  1.00 58.74  ? 338 PHE A CB   1 
ATOM   5060 C CG   . PHE A 1 338 ? 125.492 124.691 97.661  1.00 58.74  ? 338 PHE A CG   1 
ATOM   5061 C CD1  . PHE A 1 338 ? 125.204 123.879 98.742  1.00 58.74  ? 338 PHE A CD1  1 
ATOM   5062 C CD2  . PHE A 1 338 ? 124.496 124.940 96.736  1.00 58.74  ? 338 PHE A CD2  1 
ATOM   5063 C CE1  . PHE A 1 338 ? 123.949 123.323 98.891  1.00 58.74  ? 338 PHE A CE1  1 
ATOM   5064 C CE2  . PHE A 1 338 ? 123.240 124.387 96.882  1.00 58.74  ? 338 PHE A CE2  1 
ATOM   5065 C CZ   . PHE A 1 338 ? 122.967 123.579 97.960  1.00 58.74  ? 338 PHE A CZ   1 
ATOM   5066 H H    . PHE A 1 338 ? 128.572 124.433 99.294  1.00 58.74  ? 338 PHE A H    1 
ATOM   5067 H HA   . PHE A 1 338 ? 127.656 123.515 96.907  1.00 58.74  ? 338 PHE A HA   1 
ATOM   5068 H HB2  . PHE A 1 338 ? 127.014 125.880 98.255  1.00 58.74  ? 338 PHE A HB2  1 
ATOM   5069 H HB3  . PHE A 1 338 ? 126.847 125.816 96.678  1.00 58.74  ? 338 PHE A HB3  1 
ATOM   5070 H HD1  . PHE A 1 338 ? 125.864 123.701 99.373  1.00 58.74  ? 338 PHE A HD1  1 
ATOM   5071 H HD2  . PHE A 1 338 ? 124.675 125.486 96.004  1.00 58.74  ? 338 PHE A HD2  1 
ATOM   5072 H HE1  . PHE A 1 338 ? 123.766 122.776 99.620  1.00 58.74  ? 338 PHE A HE1  1 
ATOM   5073 H HE2  . PHE A 1 338 ? 122.579 124.562 96.251  1.00 58.74  ? 338 PHE A HE2  1 
ATOM   5074 H HZ   . PHE A 1 338 ? 122.121 123.206 98.059  1.00 58.74  ? 338 PHE A HZ   1 
ATOM   5075 N N    . ARG A 1 339 ? 130.382 124.303 96.935  1.00 63.13  ? 339 ARG A N    1 
ATOM   5076 C CA   . ARG A 1 339 ? 131.585 124.805 96.281  1.00 63.13  ? 339 ARG A CA   1 
ATOM   5077 C C    . ARG A 1 339 ? 131.976 123.972 95.065  1.00 63.13  ? 339 ARG A C    1 
ATOM   5078 O O    . ARG A 1 339 ? 132.136 124.513 93.967  1.00 63.13  ? 339 ARG A O    1 
ATOM   5079 C CB   . ARG A 1 339 ? 132.743 124.850 97.281  1.00 63.13  ? 339 ARG A CB   1 
ATOM   5080 C CG   . ARG A 1 339 ? 132.519 125.828 98.421  1.00 63.13  ? 339 ARG A CG   1 
ATOM   5081 C CD   . ARG A 1 339 ? 133.703 125.873 99.370  1.00 63.13  ? 339 ARG A CD   1 
ATOM   5082 N NE   . ARG A 1 339 ? 133.466 126.782 100.485 1.00 63.13  ? 339 ARG A NE   1 
ATOM   5083 C CZ   . ARG A 1 339 ? 133.694 128.089 100.451 1.00 63.13  ? 339 ARG A CZ   1 
ATOM   5084 N NH1  . ARG A 1 339 ? 134.169 128.682 99.368  1.00 63.13  ? 339 ARG A NH1  1 
ATOM   5085 N NH2  . ARG A 1 339 ? 133.437 128.819 101.532 1.00 63.13  ? 339 ARG A NH2  1 
ATOM   5086 H H    . ARG A 1 339 ? 130.519 123.646 97.473  1.00 63.13  ? 339 ARG A H    1 
ATOM   5087 H HA   . ARG A 1 339 ? 131.424 125.712 95.978  1.00 63.13  ? 339 ARG A HA   1 
ATOM   5088 H HB2  . ARG A 1 339 ? 132.860 123.967 97.665  1.00 63.13  ? 339 ARG A HB2  1 
ATOM   5089 H HB3  . ARG A 1 339 ? 133.550 125.116 96.814  1.00 63.13  ? 339 ARG A HB3  1 
ATOM   5090 H HG2  . ARG A 1 339 ? 132.387 126.718 98.057  1.00 63.13  ? 339 ARG A HG2  1 
ATOM   5091 H HG3  . ARG A 1 339 ? 131.738 125.552 98.924  1.00 63.13  ? 339 ARG A HG3  1 
ATOM   5092 H HD2  . ARG A 1 339 ? 133.854 124.985 99.731  1.00 63.13  ? 339 ARG A HD2  1 
ATOM   5093 H HD3  . ARG A 1 339 ? 134.490 126.173 98.889  1.00 63.13  ? 339 ARG A HD3  1 
ATOM   5094 H HE   . ARG A 1 339 ? 133.131 126.453 101.205 1.00 63.13  ? 339 ARG A HE   1 
ATOM   5095 H HH11 . ARG A 1 339 ? 134.340 128.223 98.661  1.00 63.13  ? 339 ARG A HH11 1 
ATOM   5096 H HH12 . ARG A 1 339 ? 134.309 129.530 99.371  1.00 63.13  ? 339 ARG A HH12 1 
ATOM   5097 H HH21 . ARG A 1 339 ? 133.128 128.444 102.241 1.00 63.13  ? 339 ARG A HH21 1 
ATOM   5098 H HH22 . ARG A 1 339 ? 133.581 129.667 101.522 1.00 63.13  ? 339 ARG A HH22 1 
ATOM   5099 N N    . THR A 1 340 ? 132.132 122.666 95.239  1.00 67.33  ? 340 THR A N    1 
ATOM   5100 C CA   . THR A 1 340 ? 132.580 121.816 94.140  1.00 67.33  ? 340 THR A CA   1 
ATOM   5101 C C    . THR A 1 340 ? 131.432 121.580 93.163  1.00 67.33  ? 340 THR A C    1 
ATOM   5102 O O    . THR A 1 340 ? 130.349 121.163 93.582  1.00 67.33  ? 340 THR A O    1 
ATOM   5103 C CB   . THR A 1 340 ? 133.097 120.481 94.669  1.00 67.33  ? 340 THR A CB   1 
ATOM   5104 O OG1  . THR A 1 340 ? 134.194 120.710 95.561  1.00 67.33  ? 340 THR A OG1  1 
ATOM   5105 C CG2  . THR A 1 340 ? 133.558 119.590 93.522  1.00 67.33  ? 340 THR A CG2  1 
ATOM   5106 H H    . THR A 1 340 ? 131.987 122.249 95.976  1.00 67.33  ? 340 THR A H    1 
ATOM   5107 H HA   . THR A 1 340 ? 133.312 122.256 93.684  1.00 67.33  ? 340 THR A HA   1 
ATOM   5108 H HB   . THR A 1 340 ? 132.385 120.024 95.144  1.00 67.33  ? 340 THR A HB   1 
ATOM   5109 H HG1  . THR A 1 340 ? 134.473 119.979 95.867  1.00 67.33  ? 340 THR A HG1  1 
ATOM   5110 H HG21 . THR A 1 340 ? 134.069 118.843 93.871  1.00 67.33  ? 340 THR A HG21 1 
ATOM   5111 H HG22 . THR A 1 340 ? 132.793 119.246 93.036  1.00 67.33  ? 340 THR A HG22 1 
ATOM   5112 H HG23 . THR A 1 340 ? 134.119 120.096 92.914  1.00 67.33  ? 340 THR A HG23 1 
ATOM   5113 N N    . PRO A 1 341 ? 131.624 121.832 91.864  1.00 64.26  ? 341 PRO A N    1 
ATOM   5114 C CA   . PRO A 1 341 ? 130.508 121.633 90.924  1.00 64.26  ? 341 PRO A CA   1 
ATOM   5115 C C    . PRO A 1 341 ? 129.928 120.231 90.959  1.00 64.26  ? 341 PRO A C    1 
ATOM   5116 O O    . PRO A 1 341 ? 128.704 120.073 90.874  1.00 64.26  ? 341 PRO A O    1 
ATOM   5117 C CB   . PRO A 1 341 ? 131.140 121.953 89.563  1.00 64.26  ? 341 PRO A CB   1 
ATOM   5118 C CG   . PRO A 1 341 ? 132.284 122.845 89.875  1.00 64.26  ? 341 PRO A CG   1 
ATOM   5119 C CD   . PRO A 1 341 ? 132.816 122.377 91.191  1.00 64.26  ? 341 PRO A CD   1 
ATOM   5120 H HA   . PRO A 1 341 ? 129.802 122.274 91.105  1.00 64.26  ? 341 PRO A HA   1 
ATOM   5121 H HB2  . PRO A 1 341 ? 131.448 121.134 89.144  1.00 64.26  ? 341 PRO A HB2  1 
ATOM   5122 H HB3  . PRO A 1 341 ? 130.494 122.407 89.000  1.00 64.26  ? 341 PRO A HB3  1 
ATOM   5123 H HG2  . PRO A 1 341 ? 132.959 122.762 89.184  1.00 64.26  ? 341 PRO A HG2  1 
ATOM   5124 H HG3  . PRO A 1 341 ? 131.972 123.762 89.940  1.00 64.26  ? 341 PRO A HG3  1 
ATOM   5125 H HD2  . PRO A 1 341 ? 133.480 121.682 91.061  1.00 64.26  ? 341 PRO A HD2  1 
ATOM   5126 H HD3  . PRO A 1 341 ? 133.178 123.126 91.689  1.00 64.26  ? 341 PRO A HD3  1 
ATOM   5127 N N    . GLN A 1 342 ? 130.769 119.202 91.085  1.00 65.02  ? 342 GLN A N    1 
ATOM   5128 C CA   . GLN A 1 342 ? 130.259 117.835 91.138  1.00 65.02  ? 342 GLN A CA   1 
ATOM   5129 C C    . GLN A 1 342 ? 129.387 117.626 92.369  1.00 65.02  ? 342 GLN A C    1 
ATOM   5130 O O    . GLN A 1 342 ? 128.306 117.028 92.289  1.00 65.02  ? 342 GLN A O    1 
ATOM   5131 C CB   . GLN A 1 342 ? 131.421 116.841 91.127  1.00 65.02  ? 342 GLN A CB   1 
ATOM   5132 C CG   . GLN A 1 342 ? 131.912 116.479 89.735  1.00 65.02  ? 342 GLN A CG   1 
ATOM   5133 C CD   . GLN A 1 342 ? 130.957 115.558 89.002  1.00 65.02  ? 342 GLN A CD   1 
ATOM   5134 O OE1  . GLN A 1 342 ? 129.881 115.235 89.504  1.00 65.02  ? 342 GLN A OE1  1 
ATOM   5135 N NE2  . GLN A 1 342 ? 131.348 115.125 87.809  1.00 65.02  ? 342 GLN A NE2  1 
ATOM   5136 H H    . GLN A 1 342 ? 131.625 119.269 91.141  1.00 65.02  ? 342 GLN A H    1 
ATOM   5137 H HA   . GLN A 1 342 ? 129.714 117.670 90.353  1.00 65.02  ? 342 GLN A HA   1 
ATOM   5138 H HB2  . GLN A 1 342 ? 132.166 117.226 91.613  1.00 65.02  ? 342 GLN A HB2  1 
ATOM   5139 H HB3  . GLN A 1 342 ? 131.134 116.022 91.561  1.00 65.02  ? 342 GLN A HB3  1 
ATOM   5140 H HG2  . GLN A 1 342 ? 132.008 117.290 89.212  1.00 65.02  ? 342 GLN A HG2  1 
ATOM   5141 H HG3  . GLN A 1 342 ? 132.768 116.028 89.808  1.00 65.02  ? 342 GLN A HG3  1 
ATOM   5142 H HE21 . GLN A 1 342 ? 132.109 115.372 87.491  1.00 65.02  ? 342 GLN A HE21 1 
ATOM   5143 H HE22 . GLN A 1 342 ? 130.842 114.600 87.354  1.00 65.02  ? 342 GLN A HE22 1 
ATOM   5144 N N    . LEU A 1 343 ? 129.844 118.112 93.524  1.00 61.85  ? 343 LEU A N    1 
ATOM   5145 C CA   . LEU A 1 343 ? 129.046 117.986 94.737  1.00 61.85  ? 343 LEU A CA   1 
ATOM   5146 C C    . LEU A 1 343 ? 127.742 118.762 94.611  1.00 61.85  ? 343 LEU A C    1 
ATOM   5147 O O    . LEU A 1 343 ? 126.696 118.314 95.092  1.00 61.85  ? 343 LEU A O    1 
ATOM   5148 C CB   . LEU A 1 343 ? 129.849 118.468 95.944  1.00 61.85  ? 343 LEU A CB   1 
ATOM   5149 C CG   . LEU A 1 343 ? 129.260 118.128 97.314  1.00 61.85  ? 343 LEU A CG   1 
ATOM   5150 C CD1  . LEU A 1 343 ? 129.170 116.625 97.504  1.00 61.85  ? 343 LEU A CD1  1 
ATOM   5151 C CD2  . LEU A 1 343 ? 130.090 118.752 98.419  1.00 61.85  ? 343 LEU A CD2  1 
ATOM   5152 H H    . LEU A 1 343 ? 130.599 118.512 93.629  1.00 61.85  ? 343 LEU A H    1 
ATOM   5153 H HA   . LEU A 1 343 ? 128.827 117.051 94.869  1.00 61.85  ? 343 LEU A HA   1 
ATOM   5154 H HB2  . LEU A 1 343 ? 130.732 118.070 95.902  1.00 61.85  ? 343 LEU A HB2  1 
ATOM   5155 H HB3  . LEU A 1 343 ? 129.927 119.433 95.894  1.00 61.85  ? 343 LEU A HB3  1 
ATOM   5156 H HG   . LEU A 1 343 ? 128.362 118.492 97.371  1.00 61.85  ? 343 LEU A HG   1 
ATOM   5157 H HD11 . LEU A 1 343 ? 128.960 116.438 98.432  1.00 61.85  ? 343 LEU A HD11 1 
ATOM   5158 H HD12 . LEU A 1 343 ? 128.471 116.273 96.931  1.00 61.85  ? 343 LEU A HD12 1 
ATOM   5159 H HD13 . LEU A 1 343 ? 130.023 116.226 97.272  1.00 61.85  ? 343 LEU A HD13 1 
ATOM   5160 H HD21 . LEU A 1 343 ? 129.682 118.543 99.274  1.00 61.85  ? 343 LEU A HD21 1 
ATOM   5161 H HD22 . LEU A 1 343 ? 130.988 118.387 98.383  1.00 61.85  ? 343 LEU A HD22 1 
ATOM   5162 H HD23 . LEU A 1 343 ? 130.117 119.712 98.290  1.00 61.85  ? 343 LEU A HD23 1 
ATOM   5163 N N    . ARG A 1 344 ? 127.783 119.928 93.966  1.00 61.92  ? 344 ARG A N    1 
ATOM   5164 C CA   . ARG A 1 344 ? 126.564 120.701 93.751  1.00 61.92  ? 344 ARG A CA   1 
ATOM   5165 C C    . ARG A 1 344 ? 125.571 119.929 92.890  1.00 61.92  ? 344 ARG A C    1 
ATOM   5166 O O    . ARG A 1 344 ? 124.373 119.874 93.197  1.00 61.92  ? 344 ARG A O    1 
ATOM   5167 C CB   . ARG A 1 344 ? 126.915 122.041 93.105  1.00 61.92  ? 344 ARG A CB   1 
ATOM   5168 C CG   . ARG A 1 344 ? 125.731 122.793 92.525  1.00 61.92  ? 344 ARG A CG   1 
ATOM   5169 C CD   . ARG A 1 344 ? 126.129 124.199 92.111  1.00 61.92  ? 344 ARG A CD   1 
ATOM   5170 N NE   . ARG A 1 344 ? 127.314 124.205 91.261  1.00 61.92  ? 344 ARG A NE   1 
ATOM   5171 C CZ   . ARG A 1 344 ? 127.954 125.299 90.874  1.00 61.92  ? 344 ARG A CZ   1 
ATOM   5172 N NH1  . ARG A 1 344 ? 127.550 126.504 91.241  1.00 61.92  ? 344 ARG A NH1  1 
ATOM   5173 N NH2  . ARG A 1 344 ? 129.029 125.181 90.100  1.00 61.92  ? 344 ARG A NH2  1 
ATOM   5174 H H    . ARG A 1 344 ? 128.496 120.288 93.646  1.00 61.92  ? 344 ARG A H    1 
ATOM   5175 H HA   . ARG A 1 344 ? 126.146 120.879 94.608  1.00 61.92  ? 344 ARG A HA   1 
ATOM   5176 H HB2  . ARG A 1 344 ? 127.325 122.610 93.775  1.00 61.92  ? 344 ARG A HB2  1 
ATOM   5177 H HB3  . ARG A 1 344 ? 127.544 121.880 92.385  1.00 61.92  ? 344 ARG A HB3  1 
ATOM   5178 H HG2  . ARG A 1 344 ? 125.405 122.328 91.738  1.00 61.92  ? 344 ARG A HG2  1 
ATOM   5179 H HG3  . ARG A 1 344 ? 125.033 122.856 93.194  1.00 61.92  ? 344 ARG A HG3  1 
ATOM   5180 H HD2  . ARG A 1 344 ? 125.400 124.602 91.613  1.00 61.92  ? 344 ARG A HD2  1 
ATOM   5181 H HD3  . ARG A 1 344 ? 126.323 124.723 92.903  1.00 61.92  ? 344 ARG A HD3  1 
ATOM   5182 H HE   . ARG A 1 344 ? 127.557 123.457 90.912  1.00 61.92  ? 344 ARG A HE   1 
ATOM   5183 H HH11 . ARG A 1 344 ? 126.857 126.594 91.741  1.00 61.92  ? 344 ARG A HH11 1 
ATOM   5184 H HH12 . ARG A 1 344 ? 127.982 127.199 90.977  1.00 61.92  ? 344 ARG A HH12 1 
ATOM   5185 H HH21 . ARG A 1 344 ? 129.300 124.402 89.856  1.00 61.92  ? 344 ARG A HH21 1 
ATOM   5186 H HH22 . ARG A 1 344 ? 129.454 125.884 89.842  1.00 61.92  ? 344 ARG A HH22 1 
ATOM   5187 N N    . LYS A 1 345 ? 126.052 119.331 91.799  1.00 59.82  ? 345 LYS A N    1 
ATOM   5188 C CA   . LYS A 1 345 ? 125.170 118.546 90.941  1.00 59.82  ? 345 LYS A CA   1 
ATOM   5189 C C    . LYS A 1 345 ? 124.574 117.373 91.704  1.00 59.82  ? 345 LYS A C    1 
ATOM   5190 O O    . LYS A 1 345 ? 123.371 117.095 91.598  1.00 59.82  ? 345 LYS A O    1 
ATOM   5191 C CB   . LYS A 1 345 ? 125.939 118.054 89.716  1.00 59.82  ? 345 LYS A CB   1 
ATOM   5192 C CG   . LYS A 1 345 ? 125.104 117.244 88.736  1.00 59.82  ? 345 LYS A CG   1 
ATOM   5193 C CD   . LYS A 1 345 ? 125.935 116.747 87.560  1.00 59.82  ? 345 LYS A CD   1 
ATOM   5194 C CE   . LYS A 1 345 ? 126.427 117.893 86.688  1.00 59.82  ? 345 LYS A CE   1 
ATOM   5195 N NZ   . LYS A 1 345 ? 127.161 117.407 85.489  1.00 59.82  ? 345 LYS A NZ   1 
ATOM   5196 H H    . LYS A 1 345 ? 126.871 119.363 91.538  1.00 59.82  ? 345 LYS A H    1 
ATOM   5197 H HA   . LYS A 1 345 ? 124.442 119.109 90.634  1.00 59.82  ? 345 LYS A HA   1 
ATOM   5198 H HB2  . LYS A 1 345 ? 126.290 118.825 89.244  1.00 59.82  ? 345 LYS A HB2  1 
ATOM   5199 H HB3  . LYS A 1 345 ? 126.672 117.491 90.013  1.00 59.82  ? 345 LYS A HB3  1 
ATOM   5200 H HG2  . LYS A 1 345 ? 124.734 116.470 89.188  1.00 59.82  ? 345 LYS A HG2  1 
ATOM   5201 H HG3  . LYS A 1 345 ? 124.390 117.801 88.388  1.00 59.82  ? 345 LYS A HG3  1 
ATOM   5202 H HD2  . LYS A 1 345 ? 126.708 116.267 87.895  1.00 59.82  ? 345 LYS A HD2  1 
ATOM   5203 H HD3  . LYS A 1 345 ? 125.391 116.161 87.010  1.00 59.82  ? 345 LYS A HD3  1 
ATOM   5204 H HE2  . LYS A 1 345 ? 125.666 118.414 86.386  1.00 59.82  ? 345 LYS A HE2  1 
ATOM   5205 H HE3  . LYS A 1 345 ? 127.031 118.451 87.201  1.00 59.82  ? 345 LYS A HE3  1 
ATOM   5206 H HZ1  . LYS A 1 345 ? 127.423 118.097 84.993  1.00 59.82  ? 345 LYS A HZ1  1 
ATOM   5207 H HZ2  . LYS A 1 345 ? 127.877 116.941 85.739  1.00 59.82  ? 345 LYS A HZ2  1 
ATOM   5208 H HZ3  . LYS A 1 345 ? 126.632 116.884 85.000  1.00 59.82  ? 345 LYS A HZ3  1 
ATOM   5209 N N    . HIS A 1 346 ? 125.401 116.674 92.482  1.00 58.60  ? 346 HIS A N    1 
ATOM   5210 C CA   . HIS A 1 346 ? 124.896 115.556 93.270  1.00 58.60  ? 346 HIS A CA   1 
ATOM   5211 C C    . HIS A 1 346 ? 123.831 116.019 94.256  1.00 58.60  ? 346 HIS A C    1 
ATOM   5212 O O    . HIS A 1 346 ? 122.792 115.367 94.413  1.00 58.60  ? 346 HIS A O    1 
ATOM   5213 C CB   . HIS A 1 346 ? 126.048 114.873 94.003  1.00 58.60  ? 346 HIS A CB   1 
ATOM   5214 C CG   . HIS A 1 346 ? 127.059 114.255 93.090  1.00 58.60  ? 346 HIS A CG   1 
ATOM   5215 N ND1  . HIS A 1 346 ? 126.760 113.874 91.800  1.00 58.60  ? 346 HIS A ND1  1 
ATOM   5216 C CD2  . HIS A 1 346 ? 128.366 113.954 93.277  1.00 58.60  ? 346 HIS A CD2  1 
ATOM   5217 C CE1  . HIS A 1 346 ? 127.838 113.364 91.232  1.00 58.60  ? 346 HIS A CE1  1 
ATOM   5218 N NE2  . HIS A 1 346 ? 128.826 113.400 92.107  1.00 58.60  ? 346 HIS A NE2  1 
ATOM   5219 H H    . HIS A 1 346 ? 126.243 116.824 92.569  1.00 58.60  ? 346 HIS A H    1 
ATOM   5220 H HA   . HIS A 1 346 ? 124.490 114.906 92.675  1.00 58.60  ? 346 HIS A HA   1 
ATOM   5221 H HB2  . HIS A 1 346 ? 126.505 115.531 94.551  1.00 58.60  ? 346 HIS A HB2  1 
ATOM   5222 H HB3  . HIS A 1 346 ? 125.688 114.170 94.566  1.00 58.60  ? 346 HIS A HB3  1 
ATOM   5223 H HD2  . HIS A 1 346 ? 128.859 114.096 94.053  1.00 58.60  ? 346 HIS A HD2  1 
ATOM   5224 H HE1  . HIS A 1 346 ? 127.892 113.034 90.364  1.00 58.60  ? 346 HIS A HE1  1 
ATOM   5225 H HE2  . HIS A 1 346 ? 129.628 113.124 91.967  1.00 58.60  ? 346 HIS A HE2  1 
ATOM   5226 N N    . THR A 1 347 ? 124.072 117.145 94.929  1.00 56.37  ? 347 THR A N    1 
ATOM   5227 C CA   . THR A 1 347 ? 123.103 117.641 95.898  1.00 56.37  ? 347 THR A CA   1 
ATOM   5228 C C    . THR A 1 347 ? 121.785 117.990 95.225  1.00 56.37  ? 347 THR A C    1 
ATOM   5229 O O    . THR A 1 347 ? 120.713 117.652 95.738  1.00 56.37  ? 347 THR A O    1 
ATOM   5230 C CB   . THR A 1 347 ? 123.663 118.858 96.629  1.00 56.37  ? 347 THR A CB   1 
ATOM   5231 O OG1  . THR A 1 347 ? 124.883 118.504 97.291  1.00 56.37  ? 347 THR A OG1  1 
ATOM   5232 C CG2  . THR A 1 347 ? 122.666 119.363 97.655  1.00 56.37  ? 347 THR A CG2  1 
ATOM   5233 H H    . THR A 1 347 ? 124.777 117.630 94.844  1.00 56.37  ? 347 THR A H    1 
ATOM   5234 H HA   . THR A 1 347 ? 122.931 116.948 96.555  1.00 56.37  ? 347 THR A HA   1 
ATOM   5235 H HB   . THR A 1 347 ? 123.835 119.568 95.991  1.00 56.37  ? 347 THR A HB   1 
ATOM   5236 H HG1  . THR A 1 347 ? 125.444 118.227 96.731  1.00 56.37  ? 347 THR A HG1  1 
ATOM   5237 H HG21 . THR A 1 347 ? 123.106 119.968 98.273  1.00 56.37  ? 347 THR A HG21 1 
ATOM   5238 H HG22 . THR A 1 347 ? 121.943 119.836 97.214  1.00 56.37  ? 347 THR A HG22 1 
ATOM   5239 H HG23 . THR A 1 347 ? 122.298 118.617 98.154  1.00 56.37  ? 347 THR A HG23 1 
ATOM   5240 N N    . PHE A 1 348 ? 121.838 118.671 94.080  1.00 56.27  ? 348 PHE A N    1 
ATOM   5241 C CA   . PHE A 1 348 ? 120.603 119.023 93.384  1.00 56.27  ? 348 PHE A CA   1 
ATOM   5242 C C    . PHE A 1 348 ? 119.838 117.773 92.968  1.00 56.27  ? 348 PHE A C    1 
ATOM   5243 O O    . PHE A 1 348 ? 118.616 117.682 93.154  1.00 56.27  ? 348 PHE A O    1 
ATOM   5244 C CB   . PHE A 1 348 ? 120.913 119.891 92.163  1.00 56.27  ? 348 PHE A CB   1 
ATOM   5245 C CG   . PHE A 1 348 ? 121.151 121.339 92.485  1.00 56.27  ? 348 PHE A CG   1 
ATOM   5246 C CD1  . PHE A 1 348 ? 120.288 122.033 93.310  1.00 56.27  ? 348 PHE A CD1  1 
ATOM   5247 C CD2  . PHE A 1 348 ? 122.240 122.006 91.956  1.00 56.27  ? 348 PHE A CD2  1 
ATOM   5248 C CE1  . PHE A 1 348 ? 120.508 123.361 93.602  1.00 56.27  ? 348 PHE A CE1  1 
ATOM   5249 C CE2  . PHE A 1 348 ? 122.462 123.333 92.245  1.00 56.27  ? 348 PHE A CE2  1 
ATOM   5250 C CZ   . PHE A 1 348 ? 121.596 124.011 93.069  1.00 56.27  ? 348 PHE A CZ   1 
ATOM   5251 H H    . PHE A 1 348 ? 122.560 118.934 93.692  1.00 56.27  ? 348 PHE A H    1 
ATOM   5252 H HA   . PHE A 1 348 ? 120.035 119.523 93.988  1.00 56.27  ? 348 PHE A HA   1 
ATOM   5253 H HB2  . PHE A 1 348 ? 121.712 119.550 91.732  1.00 56.27  ? 348 PHE A HB2  1 
ATOM   5254 H HB3  . PHE A 1 348 ? 120.164 119.845 91.548  1.00 56.27  ? 348 PHE A HB3  1 
ATOM   5255 H HD1  . PHE A 1 348 ? 119.550 121.599 93.673  1.00 56.27  ? 348 PHE A HD1  1 
ATOM   5256 H HD2  . PHE A 1 348 ? 122.830 121.553 91.398  1.00 56.27  ? 348 PHE A HD2  1 
ATOM   5257 H HE1  . PHE A 1 348 ? 119.920 123.817 94.160  1.00 56.27  ? 348 PHE A HE1  1 
ATOM   5258 H HE2  . PHE A 1 348 ? 123.199 123.771 91.884  1.00 56.27  ? 348 PHE A HE2  1 
ATOM   5259 H HZ   . PHE A 1 348 ? 121.745 124.907 93.266  1.00 56.27  ? 348 PHE A HZ   1 
ATOM   5260 N N    . ILE A 1 349 ? 120.545 116.790 92.406  1.00 56.18  ? 349 ILE A N    1 
ATOM   5261 C CA   . ILE A 1 349 ? 119.872 115.581 91.945  1.00 56.18  ? 349 ILE A CA   1 
ATOM   5262 C C    . ILE A 1 349 ? 119.233 114.852 93.119  1.00 56.18  ? 349 ILE A C    1 
ATOM   5263 O O    . ILE A 1 349 ? 118.096 114.374 93.026  1.00 56.18  ? 349 ILE A O    1 
ATOM   5264 C CB   . ILE A 1 349 ? 120.857 114.680 91.181  1.00 56.18  ? 349 ILE A CB   1 
ATOM   5265 C CG1  . ILE A 1 349 ? 121.330 115.388 89.911  1.00 56.18  ? 349 ILE A CG1  1 
ATOM   5266 C CG2  . ILE A 1 349 ? 120.198 113.355 90.835  1.00 56.18  ? 349 ILE A CG2  1 
ATOM   5267 C CD1  . ILE A 1 349 ? 122.446 114.675 89.184  1.00 56.18  ? 349 ILE A CD1  1 
ATOM   5268 H H    . ILE A 1 349 ? 121.396 116.800 92.281  1.00 56.18  ? 349 ILE A H    1 
ATOM   5269 H HA   . ILE A 1 349 ? 119.164 115.832 91.332  1.00 56.18  ? 349 ILE A HA   1 
ATOM   5270 H HB   . ILE A 1 349 ? 121.626 114.507 91.746  1.00 56.18  ? 349 ILE A HB   1 
ATOM   5271 H HG12 . ILE A 1 349 ? 120.580 115.459 89.299  1.00 56.18  ? 349 ILE A HG12 1 
ATOM   5272 H HG13 . ILE A 1 349 ? 121.646 116.275 90.142  1.00 56.18  ? 349 ILE A HG13 1 
ATOM   5273 H HG21 . ILE A 1 349 ? 120.762 112.869 90.214  1.00 56.18  ? 349 ILE A HG21 1 
ATOM   5274 H HG22 . ILE A 1 349 ? 120.083 112.833 91.644  1.00 56.18  ? 349 ILE A HG22 1 
ATOM   5275 H HG23 . ILE A 1 349 ? 119.336 113.530 90.427  1.00 56.18  ? 349 ILE A HG23 1 
ATOM   5276 H HD11 . ILE A 1 349 ? 122.828 115.278 88.527  1.00 56.18  ? 349 ILE A HD11 1 
ATOM   5277 H HD12 . ILE A 1 349 ? 123.124 114.413 89.826  1.00 56.18  ? 349 ILE A HD12 1 
ATOM   5278 H HD13 . ILE A 1 349 ? 122.087 113.890 88.742  1.00 56.18  ? 349 ILE A HD13 1 
ATOM   5279 N N    . LEU A 1 350 ? 119.944 114.760 94.243  1.00 53.98  ? 350 LEU A N    1 
ATOM   5280 C CA   . LEU A 1 350 ? 119.393 114.065 95.401  1.00 53.98  ? 350 LEU A CA   1 
ATOM   5281 C C    . LEU A 1 350 ? 118.207 114.819 95.991  1.00 53.98  ? 350 LEU A C    1 
ATOM   5282 O O    . LEU A 1 350 ? 117.237 114.200 96.449  1.00 53.98  ? 350 LEU A O    1 
ATOM   5283 C CB   . LEU A 1 350 ? 120.485 113.855 96.448  1.00 53.98  ? 350 LEU A CB   1 
ATOM   5284 C CG   . LEU A 1 350 ? 121.385 112.650 96.163  1.00 53.98  ? 350 LEU A CG   1 
ATOM   5285 C CD1  . LEU A 1 350 ? 122.663 112.709 96.980  1.00 53.98  ? 350 LEU A CD1  1 
ATOM   5286 C CD2  . LEU A 1 350 ? 120.632 111.355 96.434  1.00 53.98  ? 350 LEU A CD2  1 
ATOM   5287 H H    . LEU A 1 350 ? 120.732 115.084 94.358  1.00 53.98  ? 350 LEU A H    1 
ATOM   5288 H HA   . LEU A 1 350 ? 119.076 113.193 95.118  1.00 53.98  ? 350 LEU A HA   1 
ATOM   5289 H HB2  . LEU A 1 350 ? 121.047 114.644 96.476  1.00 53.98  ? 350 LEU A HB2  1 
ATOM   5290 H HB3  . LEU A 1 350 ? 120.068 113.717 97.313  1.00 53.98  ? 350 LEU A HB3  1 
ATOM   5291 H HG   . LEU A 1 350 ? 121.631 112.658 95.224  1.00 53.98  ? 350 LEU A HG   1 
ATOM   5292 H HD11 . LEU A 1 350 ? 123.118 111.854 96.915  1.00 53.98  ? 350 LEU A HD11 1 
ATOM   5293 H HD12 . LEU A 1 350 ? 123.230 113.413 96.628  1.00 53.98  ? 350 LEU A HD12 1 
ATOM   5294 H HD13 . LEU A 1 350 ? 122.442 112.895 97.905  1.00 53.98  ? 350 LEU A HD13 1 
ATOM   5295 H HD21 . LEU A 1 350 ? 121.256 110.613 96.405  1.00 53.98  ? 350 LEU A HD21 1 
ATOM   5296 H HD22 . LEU A 1 350 ? 120.221 111.407 97.311  1.00 53.98  ? 350 LEU A HD22 1 
ATOM   5297 H HD23 . LEU A 1 350 ? 119.948 111.237 95.757  1.00 53.98  ? 350 LEU A HD23 1 
ATOM   5298 N N    . MET A 1 351 ? 118.260 116.151 95.995  1.00 53.57  ? 351 MET A N    1 
ATOM   5299 C CA   . MET A 1 351 ? 117.121 116.928 96.469  1.00 53.57  ? 351 MET A CA   1 
ATOM   5300 C C    . MET A 1 351 ? 115.891 116.649 95.619  1.00 53.57  ? 351 MET A C    1 
ATOM   5301 O O    . MET A 1 351 ? 114.794 116.411 96.142  1.00 53.57  ? 351 MET A O    1 
ATOM   5302 C CB   . MET A 1 351 ? 117.463 118.418 96.448  1.00 53.57  ? 351 MET A CB   1 
ATOM   5303 C CG   . MET A 1 351 ? 118.281 118.882 97.643  1.00 53.57  ? 351 MET A CG   1 
ATOM   5304 S SD   . MET A 1 351 ? 118.922 120.558 97.464  1.00 53.57  ? 351 MET A SD   1 
ATOM   5305 C CE   . MET A 1 351 ? 117.408 121.485 97.241  1.00 53.57  ? 351 MET A CE   1 
ATOM   5306 H H    . MET A 1 351 ? 118.932 116.619 95.733  1.00 53.57  ? 351 MET A H    1 
ATOM   5307 H HA   . MET A 1 351 ? 116.930 116.678 97.387  1.00 53.57  ? 351 MET A HA   1 
ATOM   5308 H HB2  . MET A 1 351 ? 117.980 118.605 95.649  1.00 53.57  ? 351 MET A HB2  1 
ATOM   5309 H HB3  . MET A 1 351 ? 116.641 118.930 96.430  1.00 53.57  ? 351 MET A HB3  1 
ATOM   5310 H HG2  . MET A 1 351 ? 117.719 118.860 98.433  1.00 53.57  ? 351 MET A HG2  1 
ATOM   5311 H HG3  . MET A 1 351 ? 119.035 118.284 97.758  1.00 53.57  ? 351 MET A HG3  1 
ATOM   5312 H HE1  . MET A 1 351 ? 117.618 122.432 97.233  1.00 53.57  ? 351 MET A HE1  1 
ATOM   5313 H HE2  . MET A 1 351 ? 117.003 121.229 96.398  1.00 53.57  ? 351 MET A HE2  1 
ATOM   5314 H HE3  . MET A 1 351 ? 116.805 121.286 97.974  1.00 53.57  ? 351 MET A HE3  1 
ATOM   5315 N N    . TYR A 1 352 ? 116.059 116.662 94.296  1.00 56.60  ? 352 TYR A N    1 
ATOM   5316 C CA   . TYR A 1 352 ? 114.925 116.373 93.427  1.00 56.60  ? 352 TYR A CA   1 
ATOM   5317 C C    . TYR A 1 352 ? 114.421 114.955 93.645  1.00 56.60  ? 352 TYR A C    1 
ATOM   5318 O O    . TYR A 1 352 ? 113.211 114.707 93.618  1.00 56.60  ? 352 TYR A O    1 
ATOM   5319 C CB   . TYR A 1 352 ? 115.301 116.581 91.963  1.00 56.60  ? 352 TYR A CB   1 
ATOM   5320 C CG   . TYR A 1 352 ? 114.127 116.403 91.034  1.00 56.60  ? 352 TYR A CG   1 
ATOM   5321 C CD1  . TYR A 1 352 ? 113.120 117.353 90.976  1.00 56.60  ? 352 TYR A CD1  1 
ATOM   5322 C CD2  . TYR A 1 352 ? 114.019 115.283 90.225  1.00 56.60  ? 352 TYR A CD2  1 
ATOM   5323 C CE1  . TYR A 1 352 ? 112.040 117.197 90.136  1.00 56.60  ? 352 TYR A CE1  1 
ATOM   5324 C CE2  . TYR A 1 352 ? 112.942 115.118 89.379  1.00 56.60  ? 352 TYR A CE2  1 
ATOM   5325 C CZ   . TYR A 1 352 ? 111.955 116.080 89.339  1.00 56.60  ? 352 TYR A CZ   1 
ATOM   5326 O OH   . TYR A 1 352 ? 110.876 115.927 88.501  1.00 56.60  ? 352 TYR A OH   1 
ATOM   5327 H H    . TYR A 1 352 ? 116.798 116.829 93.889  1.00 56.60  ? 352 TYR A H    1 
ATOM   5328 H HA   . TYR A 1 352 ? 114.202 116.983 93.640  1.00 56.60  ? 352 TYR A HA   1 
ATOM   5329 H HB2  . TYR A 1 352 ? 115.643 117.481 91.848  1.00 56.60  ? 352 TYR A HB2  1 
ATOM   5330 H HB3  . TYR A 1 352 ? 115.980 115.933 91.717  1.00 56.60  ? 352 TYR A HB3  1 
ATOM   5331 H HD1  . TYR A 1 352 ? 113.174 118.109 91.514  1.00 56.60  ? 352 TYR A HD1  1 
ATOM   5332 H HD2  . TYR A 1 352 ? 114.684 114.634 90.251  1.00 56.60  ? 352 TYR A HD2  1 
ATOM   5333 H HE1  . TYR A 1 352 ? 111.373 117.844 90.107  1.00 56.60  ? 352 TYR A HE1  1 
ATOM   5334 H HE2  . TYR A 1 352 ? 112.882 114.363 88.839  1.00 56.60  ? 352 TYR A HE2  1 
ATOM   5335 H HH   . TYR A 1 352 ? 110.946 115.209 88.070  1.00 56.60  ? 352 TYR A HH   1 
ATOM   5336 N N    . LEU A 1 353 ? 115.336 114.006 93.847  1.00 54.77  ? 353 LEU A N    1 
ATOM   5337 C CA   . LEU A 1 353 ? 114.929 112.627 94.093  1.00 54.77  ? 353 LEU A CA   1 
ATOM   5338 C C    . LEU A 1 353 ? 114.062 112.530 95.341  1.00 54.77  ? 353 LEU A C    1 
ATOM   5339 O O    . LEU A 1 353 ? 112.996 111.902 95.325  1.00 54.77  ? 353 LEU A O    1 
ATOM   5340 C CB   . LEU A 1 353 ? 116.163 111.739 94.234  1.00 54.77  ? 353 LEU A CB   1 
ATOM   5341 C CG   . LEU A 1 353 ? 116.451 110.774 93.090  1.00 54.77  ? 353 LEU A CG   1 
ATOM   5342 C CD1  . LEU A 1 353 ? 117.791 110.098 93.329  1.00 54.77  ? 353 LEU A CD1  1 
ATOM   5343 C CD2  . LEU A 1 353 ? 115.332 109.753 92.972  1.00 54.77  ? 353 LEU A CD2  1 
ATOM   5344 H H    . LEU A 1 353 ? 116.186 114.136 93.845  1.00 54.77  ? 353 LEU A H    1 
ATOM   5345 H HA   . LEU A 1 353 ? 114.409 112.310 93.338  1.00 54.77  ? 353 LEU A HA   1 
ATOM   5346 H HB2  . LEU A 1 353 ? 116.942 112.309 94.328  1.00 54.77  ? 353 LEU A HB2  1 
ATOM   5347 H HB3  . LEU A 1 353 ? 116.061 111.206 95.038  1.00 54.77  ? 353 LEU A HB3  1 
ATOM   5348 H HG   . LEU A 1 353 ? 116.503 111.268 92.256  1.00 54.77  ? 353 LEU A HG   1 
ATOM   5349 H HD11 . LEU A 1 353 ? 117.941 109.426 92.650  1.00 54.77  ? 353 LEU A HD11 1 
ATOM   5350 H HD12 . LEU A 1 353 ? 118.491 110.769 93.290  1.00 54.77  ? 353 LEU A HD12 1 
ATOM   5351 H HD13 . LEU A 1 353 ? 117.780 109.684 94.206  1.00 54.77  ? 353 LEU A HD13 1 
ATOM   5352 H HD21 . LEU A 1 353 ? 115.657 108.974 92.496  1.00 54.77  ? 353 LEU A HD21 1 
ATOM   5353 H HD22 . LEU A 1 353 ? 115.047 109.497 93.863  1.00 54.77  ? 353 LEU A HD22 1 
ATOM   5354 H HD23 . LEU A 1 353 ? 114.590 110.152 92.492  1.00 54.77  ? 353 LEU A HD23 1 
ATOM   5355 N N    . TRP A 1 354 ? 114.503 113.153 96.435  1.00 51.68  ? 354 TRP A N    1 
ATOM   5356 C CA   . TRP A 1 354 ? 113.714 113.131 97.663  1.00 51.68  ? 354 TRP A CA   1 
ATOM   5357 C C    . TRP A 1 354 ? 112.345 113.754 97.431  1.00 51.68  ? 354 TRP A C    1 
ATOM   5358 O O    . TRP A 1 354 ? 111.318 113.213 97.863  1.00 51.68  ? 354 TRP A O    1 
ATOM   5359 C CB   . TRP A 1 354 ? 114.445 113.877 98.779  1.00 51.68  ? 354 TRP A CB   1 
ATOM   5360 C CG   . TRP A 1 354 ? 115.444 113.063 99.530  1.00 51.68  ? 354 TRP A CG   1 
ATOM   5361 C CD1  . TRP A 1 354 ? 116.796 113.084 99.376  1.00 51.68  ? 354 TRP A CD1  1 
ATOM   5362 C CD2  . TRP A 1 354 ? 115.173 112.119 100.568 1.00 51.68  ? 354 TRP A CD2  1 
ATOM   5363 N NE1  . TRP A 1 354 ? 117.385 112.207 100.251 1.00 51.68  ? 354 TRP A NE1  1 
ATOM   5364 C CE2  . TRP A 1 354 ? 116.408 111.601 100.994 1.00 51.68  ? 354 TRP A CE2  1 
ATOM   5365 C CE3  . TRP A 1 354 ? 114.004 111.657 101.176 1.00 51.68  ? 354 TRP A CE3  1 
ATOM   5366 C CZ2  . TRP A 1 354 ? 116.510 110.645 101.998 1.00 51.68  ? 354 TRP A CZ2  1 
ATOM   5367 C CZ3  . TRP A 1 354 ? 114.107 110.708 102.173 1.00 51.68  ? 354 TRP A CZ3  1 
ATOM   5368 C CH2  . TRP A 1 354 ? 115.351 110.212 102.574 1.00 51.68  ? 354 TRP A CH2  1 
ATOM   5369 H H    . TRP A 1 354 ? 115.244 113.586 96.491  1.00 51.68  ? 354 TRP A H    1 
ATOM   5370 H HA   . TRP A 1 354 ? 113.587 112.212 97.945  1.00 51.68  ? 354 TRP A HA   1 
ATOM   5371 H HB2  . TRP A 1 354 ? 114.915 114.631 98.390  1.00 51.68  ? 354 TRP A HB2  1 
ATOM   5372 H HB3  . TRP A 1 354 ? 113.789 114.197 99.418  1.00 51.68  ? 354 TRP A HB3  1 
ATOM   5373 H HD1  . TRP A 1 354 ? 117.255 113.616 98.767  1.00 51.68  ? 354 TRP A HD1  1 
ATOM   5374 H HE1  . TRP A 1 354 ? 118.230 112.061 100.320 1.00 51.68  ? 354 TRP A HE1  1 
ATOM   5375 H HE3  . TRP A 1 354 ? 113.173 111.982 100.915 1.00 51.68  ? 354 TRP A HE3  1 
ATOM   5376 H HZ2  . TRP A 1 354 ? 117.336 110.312 102.267 1.00 51.68  ? 354 TRP A HZ2  1 
ATOM   5377 H HZ3  . TRP A 1 354 ? 113.335 110.393 102.586 1.00 51.68  ? 354 TRP A HZ3  1 
ATOM   5378 H HH2  . TRP A 1 354 ? 115.389 109.573 103.249 1.00 51.68  ? 354 TRP A HH2  1 
ATOM   5379 N N    . PHE A 1 355 ? 112.313 114.903 96.753  1.00 57.58  ? 355 PHE A N    1 
ATOM   5380 C CA   . PHE A 1 355 ? 111.046 115.594 96.547  1.00 57.58  ? 355 PHE A CA   1 
ATOM   5381 C C    . PHE A 1 355 ? 110.077 114.737 95.744  1.00 57.58  ? 355 PHE A C    1 
ATOM   5382 O O    . PHE A 1 355 ? 108.904 114.593 96.111  1.00 57.58  ? 355 PHE A O    1 
ATOM   5383 C CB   . PHE A 1 355 ? 111.288 116.928 95.846  1.00 57.58  ? 355 PHE A CB   1 
ATOM   5384 C CG   . PHE A 1 355 ? 110.035 117.698 95.576  1.00 57.58  ? 355 PHE A CG   1 
ATOM   5385 C CD1  . PHE A 1 355 ? 109.454 118.463 96.568  1.00 57.58  ? 355 PHE A CD1  1 
ATOM   5386 C CD2  . PHE A 1 355 ? 109.436 117.655 94.331  1.00 57.58  ? 355 PHE A CD2  1 
ATOM   5387 C CE1  . PHE A 1 355 ? 108.300 119.173 96.326  1.00 57.58  ? 355 PHE A CE1  1 
ATOM   5388 C CE2  . PHE A 1 355 ? 108.282 118.364 94.082  1.00 57.58  ? 355 PHE A CE2  1 
ATOM   5389 C CZ   . PHE A 1 355 ? 107.712 119.124 95.081  1.00 57.58  ? 355 PHE A CZ   1 
ATOM   5390 H H    . PHE A 1 355 ? 112.998 115.294 96.409  1.00 57.58  ? 355 PHE A H    1 
ATOM   5391 H HA   . PHE A 1 355 ? 110.641 115.777 97.409  1.00 57.58  ? 355 PHE A HA   1 
ATOM   5392 H HB2  . PHE A 1 355 ? 111.860 117.477 96.404  1.00 57.58  ? 355 PHE A HB2  1 
ATOM   5393 H HB3  . PHE A 1 355 ? 111.722 116.760 94.995  1.00 57.58  ? 355 PHE A HB3  1 
ATOM   5394 H HD1  . PHE A 1 355 ? 109.848 118.499 97.410  1.00 57.58  ? 355 PHE A HD1  1 
ATOM   5395 H HD2  . PHE A 1 355 ? 109.817 117.144 93.655  1.00 57.58  ? 355 PHE A HD2  1 
ATOM   5396 H HE1  . PHE A 1 355 ? 107.918 119.685 97.001  1.00 57.58  ? 355 PHE A HE1  1 
ATOM   5397 H HE2  . PHE A 1 355 ? 107.887 118.329 93.241  1.00 57.58  ? 355 PHE A HE2  1 
ATOM   5398 H HZ   . PHE A 1 355 ? 106.933 119.603 94.915  1.00 57.58  ? 355 PHE A HZ   1 
ATOM   5399 N N    . THR A 1 356 ? 110.551 114.155 94.639  1.00 60.27  ? 356 THR A N    1 
ATOM   5400 C CA   . THR A 1 356 ? 109.674 113.335 93.812  1.00 60.27  ? 356 THR A CA   1 
ATOM   5401 C C    . THR A 1 356 ? 109.209 112.103 94.568  1.00 60.27  ? 356 THR A C    1 
ATOM   5402 O O    . THR A 1 356 ? 108.045 111.706 94.457  1.00 60.27  ? 356 THR A O    1 
ATOM   5403 C CB   . THR A 1 356 ? 110.378 112.915 92.524  1.00 60.27  ? 356 THR A CB   1 
ATOM   5404 O OG1  . THR A 1 356 ? 111.462 112.032 92.835  1.00 60.27  ? 356 THR A OG1  1 
ATOM   5405 C CG2  . THR A 1 356 ? 110.903 114.128 91.771  1.00 60.27  ? 356 THR A CG2  1 
ATOM   5406 H H    . THR A 1 356 ? 111.361 114.218 94.356  1.00 60.27  ? 356 THR A H    1 
ATOM   5407 H HA   . THR A 1 356 ? 108.890 113.853 93.572  1.00 60.27  ? 356 THR A HA   1 
ATOM   5408 H HB   . THR A 1 356 ? 109.746 112.453 91.951  1.00 60.27  ? 356 THR A HB   1 
ATOM   5409 H HG1  . THR A 1 356 ? 112.028 112.428 93.313  1.00 60.27  ? 356 THR A HG1  1 
ATOM   5410 H HG21 . THR A 1 356 ? 110.586 114.110 90.855  1.00 60.27  ? 356 THR A HG21 1 
ATOM   5411 H HG22 . THR A 1 356 ? 110.597 114.945 92.195  1.00 60.27  ? 356 THR A HG22 1 
ATOM   5412 H HG23 . THR A 1 356 ? 111.872 114.118 91.765  1.00 60.27  ? 356 THR A HG23 1 
ATOM   5413 N N    . SER A 1 357 ? 110.101 111.477 95.338  1.00 58.76  ? 357 SER A N    1 
ATOM   5414 C CA   . SER A 1 357 ? 109.705 110.300 96.100  1.00 58.76  ? 357 SER A CA   1 
ATOM   5415 C C    . SER A 1 357 ? 108.596 110.640 97.085  1.00 58.76  ? 357 SER A C    1 
ATOM   5416 O O    . SER A 1 357 ? 107.584 109.932 97.170  1.00 58.76  ? 357 SER A O    1 
ATOM   5417 C CB   . SER A 1 357 ? 110.918 109.722 96.827  1.00 58.76  ? 357 SER A CB   1 
ATOM   5418 O OG   . SER A 1 357 ? 111.573 110.720 97.589  1.00 58.76  ? 357 SER A OG   1 
ATOM   5419 H H    . SER A 1 357 ? 110.924 111.707 95.432  1.00 58.76  ? 357 SER A H    1 
ATOM   5420 H HA   . SER A 1 357 ? 109.369 109.624 95.491  1.00 58.76  ? 357 SER A HA   1 
ATOM   5421 H HB2  . SER A 1 357 ? 110.624 109.012 97.420  1.00 58.76  ? 357 SER A HB2  1 
ATOM   5422 H HB3  . SER A 1 357 ? 111.539 109.369 96.171  1.00 58.76  ? 357 SER A HB3  1 
ATOM   5423 H HG   . SER A 1 357 ? 111.054 111.023 98.176  1.00 58.76  ? 357 SER A HG   1 
ATOM   5424 N N    . SER A 1 358 ? 108.753 111.740 97.823  1.00 57.95  ? 358 SER A N    1 
ATOM   5425 C CA   . SER A 1 358 ? 107.736 112.098 98.806  1.00 57.95  ? 358 SER A CA   1 
ATOM   5426 C C    . SER A 1 358 ? 106.418 112.449 98.129  1.00 57.95  ? 358 SER A C    1 
ATOM   5427 O O    . SER A 1 358 ? 105.344 112.025 98.583  1.00 57.95  ? 358 SER A O    1 
ATOM   5428 C CB   . SER A 1 358 ? 108.222 113.263 99.662  1.00 57.95  ? 358 SER A CB   1 
ATOM   5429 O OG   . SER A 1 358 ? 107.503 113.328 100.880 1.00 57.95  ? 358 SER A OG   1 
ATOM   5430 H H    . SER A 1 358 ? 109.420 112.281 97.776  1.00 57.95  ? 358 SER A H    1 
ATOM   5431 H HA   . SER A 1 358 ? 107.582 111.340 99.392  1.00 57.95  ? 358 SER A HA   1 
ATOM   5432 H HB2  . SER A 1 358 ? 109.166 113.147 99.850  1.00 57.95  ? 358 SER A HB2  1 
ATOM   5433 H HB3  . SER A 1 358 ? 108.084 114.090 99.174  1.00 57.95  ? 358 SER A HB3  1 
ATOM   5434 H HG   . SER A 1 358 ? 107.795 113.957 101.353 1.00 57.95  ? 358 SER A HG   1 
ATOM   5435 N N    . VAL A 1 359 ? 106.477 113.216 97.038  1.00 62.80  ? 359 VAL A N    1 
ATOM   5436 C CA   . VAL A 1 359 ? 105.254 113.611 96.347  1.00 62.80  ? 359 VAL A CA   1 
ATOM   5437 C C    . VAL A 1 359 ? 104.527 112.388 95.811  1.00 62.80  ? 359 VAL A C    1 
ATOM   5438 O O    . VAL A 1 359 ? 103.303 112.275 95.934  1.00 62.80  ? 359 VAL A O    1 
ATOM   5439 C CB   . VAL A 1 359 ? 105.574 114.614 95.224  1.00 62.80  ? 359 VAL A CB   1 
ATOM   5440 C CG1  . VAL A 1 359 ? 104.393 114.750 94.281  1.00 62.80  ? 359 VAL A CG1  1 
ATOM   5441 C CG2  . VAL A 1 359 ? 105.937 115.964 95.816  1.00 62.80  ? 359 VAL A CG2  1 
ATOM   5442 H H    . VAL A 1 359 ? 107.202 113.517 96.687  1.00 62.80  ? 359 VAL A H    1 
ATOM   5443 H HA   . VAL A 1 359 ? 104.666 114.052 96.980  1.00 62.80  ? 359 VAL A HA   1 
ATOM   5444 H HB   . VAL A 1 359 ? 106.333 114.292 94.715  1.00 62.80  ? 359 VAL A HB   1 
ATOM   5445 H HG11 . VAL A 1 359 ? 104.505 115.557 93.755  1.00 62.80  ? 359 VAL A HG11 1 
ATOM   5446 H HG12 . VAL A 1 359 ? 104.361 113.978 93.695  1.00 62.80  ? 359 VAL A HG12 1 
ATOM   5447 H HG13 . VAL A 1 359 ? 103.577 114.809 94.802  1.00 62.80  ? 359 VAL A HG13 1 
ATOM   5448 H HG21 . VAL A 1 359 ? 106.174 116.570 95.096  1.00 62.80  ? 359 VAL A HG21 1 
ATOM   5449 H HG22 . VAL A 1 359 ? 105.174 116.310 96.304  1.00 62.80  ? 359 VAL A HG22 1 
ATOM   5450 H HG23 . VAL A 1 359 ? 106.691 115.851 96.415  1.00 62.80  ? 359 VAL A HG23 1 
ATOM   5451 N N    . LEU A 1 360 ? 105.262 111.457 95.201  1.00 64.17  ? 360 LEU A N    1 
ATOM   5452 C CA   . LEU A 1 360 ? 104.623 110.270 94.649  1.00 64.17  ? 360 LEU A CA   1 
ATOM   5453 C C    . LEU A 1 360 ? 104.040 109.398 95.753  1.00 64.17  ? 360 LEU A C    1 
ATOM   5454 O O    . LEU A 1 360 ? 102.957 108.826 95.590  1.00 64.17  ? 360 LEU A O    1 
ATOM   5455 C CB   . LEU A 1 360 ? 105.623 109.484 93.803  1.00 64.17  ? 360 LEU A CB   1 
ATOM   5456 C CG   . LEU A 1 360 ? 105.035 108.656 92.658  1.00 64.17  ? 360 LEU A CG   1 
ATOM   5457 C CD1  . LEU A 1 360 ? 104.300 109.548 91.668  1.00 64.17  ? 360 LEU A CD1  1 
ATOM   5458 C CD2  . LEU A 1 360 ? 106.126 107.870 91.949  1.00 64.17  ? 360 LEU A CD2  1 
ATOM   5459 H H    . LEU A 1 360 ? 106.115 111.490 95.098  1.00 64.17  ? 360 LEU A H    1 
ATOM   5460 H HA   . LEU A 1 360 ? 103.891 110.551 94.078  1.00 64.17  ? 360 LEU A HA   1 
ATOM   5461 H HB2  . LEU A 1 360 ? 106.251 110.111 93.412  1.00 64.17  ? 360 LEU A HB2  1 
ATOM   5462 H HB3  . LEU A 1 360 ? 106.101 108.872 94.385  1.00 64.17  ? 360 LEU A HB3  1 
ATOM   5463 H HG   . LEU A 1 360 ? 104.397 108.023 93.021  1.00 64.17  ? 360 LEU A HG   1 
ATOM   5464 H HD11 . LEU A 1 360 ? 104.190 109.066 90.834  1.00 64.17  ? 360 LEU A HD11 1 
ATOM   5465 H HD12 . LEU A 1 360 ? 103.431 109.780 92.032  1.00 64.17  ? 360 LEU A HD12 1 
ATOM   5466 H HD13 . LEU A 1 360 ? 104.824 110.350 91.518  1.00 64.17  ? 360 LEU A HD13 1 
ATOM   5467 H HD21 . LEU A 1 360 ? 105.714 107.272 91.306  1.00 64.17  ? 360 LEU A HD21 1 
ATOM   5468 H HD22 . LEU A 1 360 ? 106.715 108.491 91.493  1.00 64.17  ? 360 LEU A HD22 1 
ATOM   5469 H HD23 . LEU A 1 360 ? 106.627 107.359 92.602  1.00 64.17  ? 360 LEU A HD23 1 
ATOM   5470 N N    . TYR A 1 361 ? 104.735 109.288 96.887  1.00 64.17  ? 361 TYR A N    1 
ATOM   5471 C CA   . TYR A 1 361 ? 104.192 108.519 98.002  1.00 64.17  ? 361 TYR A CA   1 
ATOM   5472 C C    . TYR A 1 361 ? 102.870 109.106 98.475  1.00 64.17  ? 361 TYR A C    1 
ATOM   5473 O O    . TYR A 1 361 ? 101.880 108.383 98.663  1.00 64.17  ? 361 TYR A O    1 
ATOM   5474 C CB   . TYR A 1 361 ? 105.196 108.489 99.152  1.00 64.17  ? 361 TYR A CB   1 
ATOM   5475 C CG   . TYR A 1 361 ? 104.648 107.871 100.416 1.00 64.17  ? 361 TYR A CG   1 
ATOM   5476 C CD1  . TYR A 1 361 ? 104.646 106.496 100.594 1.00 64.17  ? 361 TYR A CD1  1 
ATOM   5477 C CD2  . TYR A 1 361 ? 104.135 108.664 101.431 1.00 64.17  ? 361 TYR A CD2  1 
ATOM   5478 C CE1  . TYR A 1 361 ? 104.148 105.928 101.747 1.00 64.17  ? 361 TYR A CE1  1 
ATOM   5479 C CE2  . TYR A 1 361 ? 103.635 108.107 102.587 1.00 64.17  ? 361 TYR A CE2  1 
ATOM   5480 C CZ   . TYR A 1 361 ? 103.644 106.739 102.741 1.00 64.17  ? 361 TYR A CZ   1 
ATOM   5481 O OH   . TYR A 1 361 ? 103.145 106.179 103.895 1.00 64.17  ? 361 TYR A OH   1 
ATOM   5482 H H    . TYR A 1 361 ? 105.504 109.643 97.034  1.00 64.17  ? 361 TYR A H    1 
ATOM   5483 H HA   . TYR A 1 361 ? 104.033 107.607 97.713  1.00 64.17  ? 361 TYR A HA   1 
ATOM   5484 H HB2  . TYR A 1 361 ? 105.976 107.983 98.882  1.00 64.17  ? 361 TYR A HB2  1 
ATOM   5485 H HB3  . TYR A 1 361 ? 105.455 109.400 99.360  1.00 64.17  ? 361 TYR A HB3  1 
ATOM   5486 H HD1  . TYR A 1 361 ? 104.986 105.947 99.925  1.00 64.17  ? 361 TYR A HD1  1 
ATOM   5487 H HD2  . TYR A 1 361 ? 104.128 109.589 101.330 1.00 64.17  ? 361 TYR A HD2  1 
ATOM   5488 H HE1  . TYR A 1 361 ? 104.153 105.004 101.854 1.00 64.17  ? 361 TYR A HE1  1 
ATOM   5489 H HE2  . TYR A 1 361 ? 103.294 108.651 103.259 1.00 64.17  ? 361 TYR A HE2  1 
ATOM   5490 H HH   . TYR A 1 361 ? 102.895 106.782 104.423 1.00 64.17  ? 361 TYR A HH   1 
ATOM   5491 N N    . GLN A 1 362 ? 102.838 110.422 98.686  1.00 66.90  ? 362 GLN A N    1 
ATOM   5492 C CA   . GLN A 1 362 ? 101.611 111.033 99.179  1.00 66.90  ? 362 GLN A CA   1 
ATOM   5493 C C    . GLN A 1 362 ? 100.502 110.933 98.142  1.00 66.90  ? 362 GLN A C    1 
ATOM   5494 O O    . GLN A 1 362 ? 99.338  110.716 98.491  1.00 66.90  ? 362 GLN A O    1 
ATOM   5495 C CB   . GLN A 1 362 ? 101.857 112.486 99.573  1.00 66.90  ? 362 GLN A CB   1 
ATOM   5496 C CG   . GLN A 1 362 ? 101.046 112.926 100.784 1.00 66.90  ? 362 GLN A CG   1 
ATOM   5497 C CD   . GLN A 1 362 ? 101.400 112.152 102.037 1.00 66.90  ? 362 GLN A CD   1 
ATOM   5498 O OE1  . GLN A 1 362 ? 102.254 111.267 102.015 1.00 66.90  ? 362 GLN A OE1  1 
ATOM   5499 N NE2  . GLN A 1 362 ? 100.743 112.484 103.142 1.00 66.90  ? 362 GLN A NE2  1 
ATOM   5500 H H    . GLN A 1 362 ? 103.492 110.965 98.556  1.00 66.90  ? 362 GLN A H    1 
ATOM   5501 H HA   . GLN A 1 362 ? 101.328 110.554 99.967  1.00 66.90  ? 362 GLN A HA   1 
ATOM   5502 H HB2  . GLN A 1 362 ? 102.797 112.602 99.783  1.00 66.90  ? 362 GLN A HB2  1 
ATOM   5503 H HB3  . GLN A 1 362 ? 101.612 113.055 98.827  1.00 66.90  ? 362 GLN A HB3  1 
ATOM   5504 H HG2  . GLN A 1 362 ? 101.216 113.862 100.963 1.00 66.90  ? 362 GLN A HG2  1 
ATOM   5505 H HG3  . GLN A 1 362 ? 100.104 112.788 100.601 1.00 66.90  ? 362 GLN A HG3  1 
ATOM   5506 H HE21 . GLN A 1 362 ? 100.152 113.109 103.120 1.00 66.90  ? 362 GLN A HE21 1 
ATOM   5507 H HE22 . GLN A 1 362 ? 100.908 112.074 103.879 1.00 66.90  ? 362 GLN A HE22 1 
ATOM   5508 N N    . GLY A 1 363 ? 100.841 111.077 96.861  1.00 69.13  ? 363 GLY A N    1 
ATOM   5509 C CA   . GLY A 1 363 ? 99.838  110.905 95.827  1.00 69.13  ? 363 GLY A CA   1 
ATOM   5510 C C    . GLY A 1 363 ? 99.246  109.510 95.830  1.00 69.13  ? 363 GLY A C    1 
ATOM   5511 O O    . GLY A 1 363 ? 98.029  109.341 95.719  1.00 69.13  ? 363 GLY A O    1 
ATOM   5512 H H    . GLY A 1 363 ? 101.629 111.270 96.575  1.00 69.13  ? 363 GLY A H    1 
ATOM   5513 H HA2  . GLY A 1 363 ? 99.121  111.544 95.961  1.00 69.13  ? 363 GLY A HA2  1 
ATOM   5514 H HA3  . GLY A 1 363 ? 100.237 111.068 94.958  1.00 69.13  ? 363 GLY A HA3  1 
ATOM   5515 N N    . LEU A 1 364 ? 100.095 108.491 95.968  1.00 70.63  ? 364 LEU A N    1 
ATOM   5516 C CA   . LEU A 1 364 ? 99.593  107.123 96.015  1.00 70.63  ? 364 LEU A CA   1 
ATOM   5517 C C    . LEU A 1 364 ? 98.655  106.928 97.197  1.00 70.63  ? 364 LEU A C    1 
ATOM   5518 O O    . LEU A 1 364 ? 97.541  106.419 97.038  1.00 70.63  ? 364 LEU A O    1 
ATOM   5519 C CB   . LEU A 1 364 ? 100.754 106.130 96.090  1.00 70.63  ? 364 LEU A CB   1 
ATOM   5520 C CG   . LEU A 1 364 ? 101.119 105.406 94.794  1.00 70.63  ? 364 LEU A CG   1 
ATOM   5521 C CD1  . LEU A 1 364 ? 102.309 104.498 95.026  1.00 70.63  ? 364 LEU A CD1  1 
ATOM   5522 C CD2  . LEU A 1 364 ? 99.941  104.609 94.253  1.00 70.63  ? 364 LEU A CD2  1 
ATOM   5523 H H    . LEU A 1 364 ? 100.950 108.566 96.032  1.00 70.63  ? 364 LEU A H    1 
ATOM   5524 H HA   . LEU A 1 364 ? 99.090  106.948 95.206  1.00 70.63  ? 364 LEU A HA   1 
ATOM   5525 H HB2  . LEU A 1 364 ? 101.544 106.607 96.387  1.00 70.63  ? 364 LEU A HB2  1 
ATOM   5526 H HB3  . LEU A 1 364 ? 100.526 105.450 96.744  1.00 70.63  ? 364 LEU A HB3  1 
ATOM   5527 H HG   . LEU A 1 364 ? 101.370 106.064 94.128  1.00 70.63  ? 364 LEU A HG   1 
ATOM   5528 H HD11 . LEU A 1 364 ? 102.535 104.054 94.193  1.00 70.63  ? 364 LEU A HD11 1 
ATOM   5529 H HD12 . LEU A 1 364 ? 103.056 105.034 95.329  1.00 70.63  ? 364 LEU A HD12 1 
ATOM   5530 H HD13 . LEU A 1 364 ? 102.078 103.840 95.700  1.00 70.63  ? 364 LEU A HD13 1 
ATOM   5531 H HD21 . LEU A 1 364 ? 100.267 103.971 93.599  1.00 70.63  ? 364 LEU A HD21 1 
ATOM   5532 H HD22 . LEU A 1 364 ? 99.513  104.142 94.987  1.00 70.63  ? 364 LEU A HD22 1 
ATOM   5533 H HD23 . LEU A 1 364 ? 99.311  105.217 93.835  1.00 70.63  ? 364 LEU A HD23 1 
ATOM   5534 N N    . ILE A 1 365 ? 99.081  107.339 98.394  1.00 73.89  ? 365 ILE A N    1 
ATOM   5535 C CA   . ILE A 1 365 ? 98.234  107.112 99.565  1.00 73.89  ? 365 ILE A CA   1 
ATOM   5536 C C    . ILE A 1 365 ? 96.922  107.874 99.423  1.00 73.89  ? 365 ILE A C    1 
ATOM   5537 O O    . ILE A 1 365 ? 95.854  107.374 99.797  1.00 73.89  ? 365 ILE A O    1 
ATOM   5538 C CB   . ILE A 1 365 ? 98.968  107.486 100.866 1.00 73.89  ? 365 ILE A CB   1 
ATOM   5539 C CG1  . ILE A 1 365 ? 98.089  107.159 102.077 1.00 73.89  ? 365 ILE A CG1  1 
ATOM   5540 C CG2  . ILE A 1 365 ? 99.329  108.949 100.875 1.00 73.89  ? 365 ILE A CG2  1 
ATOM   5541 C CD1  . ILE A 1 365 ? 98.768  107.379 103.411 1.00 73.89  ? 365 ILE A CD1  1 
ATOM   5542 H H    . ILE A 1 365 ? 99.827  107.735 98.551  1.00 73.89  ? 365 ILE A H    1 
ATOM   5543 H HA   . ILE A 1 365 ? 98.022  106.168 99.614  1.00 73.89  ? 365 ILE A HA   1 
ATOM   5544 H HB   . ILE A 1 365 ? 99.783  106.964 100.924 1.00 73.89  ? 365 ILE A HB   1 
ATOM   5545 H HG12 . ILE A 1 365 ? 97.301  107.725 102.055 1.00 73.89  ? 365 ILE A HG12 1 
ATOM   5546 H HG13 . ILE A 1 365 ? 97.824  106.227 102.029 1.00 73.89  ? 365 ILE A HG13 1 
ATOM   5547 H HG21 . ILE A 1 365 ? 99.887  109.136 101.645 1.00 73.89  ? 365 ILE A HG21 1 
ATOM   5548 H HG22 . ILE A 1 365 ? 99.815  109.138 100.063 1.00 73.89  ? 365 ILE A HG22 1 
ATOM   5549 H HG23 . ILE A 1 365 ? 98.520  109.482 100.913 1.00 73.89  ? 365 ILE A HG23 1 
ATOM   5550 H HD11 . ILE A 1 365 ? 98.187  107.055 104.116 1.00 73.89  ? 365 ILE A HD11 1 
ATOM   5551 H HD12 . ILE A 1 365 ? 99.606  106.891 103.422 1.00 73.89  ? 365 ILE A HD12 1 
ATOM   5552 H HD13 . ILE A 1 365 ? 98.935  108.327 103.530 1.00 73.89  ? 365 ILE A HD13 1 
ATOM   5553 N N    . MET A 1 366 ? 96.974  109.093 98.879  1.00 76.42  ? 366 MET A N    1 
ATOM   5554 C CA   . MET A 1 366 ? 95.754  109.873 98.704  1.00 76.42  ? 366 MET A CA   1 
ATOM   5555 C C    . MET A 1 366 ? 94.809  109.201 97.718  1.00 76.42  ? 366 MET A C    1 
ATOM   5556 O O    . MET A 1 366 ? 93.593  109.161 97.939  1.00 76.42  ? 366 MET A O    1 
ATOM   5557 C CB   . MET A 1 366 ? 96.106  111.283 98.231  1.00 76.42  ? 366 MET A CB   1 
ATOM   5558 C CG   . MET A 1 366 ? 94.914  112.218 98.096  1.00 76.42  ? 366 MET A CG   1 
ATOM   5559 S SD   . MET A 1 366 ? 94.004  112.437 99.637  1.00 76.42  ? 366 MET A SD   1 
ATOM   5560 C CE   . MET A 1 366 ? 95.275  113.121 100.698 1.00 76.42  ? 366 MET A CE   1 
ATOM   5561 H H    . MET A 1 366 ? 97.691  109.481 98.608  1.00 76.42  ? 366 MET A H    1 
ATOM   5562 H HA   . MET A 1 366 ? 95.308  109.948 99.561  1.00 76.42  ? 366 MET A HA   1 
ATOM   5563 H HB2  . MET A 1 366 ? 96.725  111.679 98.864  1.00 76.42  ? 366 MET A HB2  1 
ATOM   5564 H HB3  . MET A 1 366 ? 96.527  111.220 97.360  1.00 76.42  ? 366 MET A HB3  1 
ATOM   5565 H HG2  . MET A 1 366 ? 95.232  113.090 97.812  1.00 76.42  ? 366 MET A HG2  1 
ATOM   5566 H HG3  . MET A 1 366 ? 94.302  111.860 97.434  1.00 76.42  ? 366 MET A HG3  1 
ATOM   5567 H HE1  . MET A 1 366 ? 94.870  113.399 101.534 1.00 76.42  ? 366 MET A HE1  1 
ATOM   5568 H HE2  . MET A 1 366 ? 95.946  112.442 100.865 1.00 76.42  ? 366 MET A HE2  1 
ATOM   5569 H HE3  . MET A 1 366 ? 95.678  113.885 100.256 1.00 76.42  ? 366 MET A HE3  1 
ATOM   5570 N N    . HIS A 1 367 ? 95.347  108.666 96.627  1.00 83.15  ? 367 HIS A N    1 
ATOM   5571 C CA   . HIS A 1 367 ? 94.541  108.052 95.581  1.00 83.15  ? 367 HIS A CA   1 
ATOM   5572 C C    . HIS A 1 367 ? 94.161  106.607 95.894  1.00 83.15  ? 367 HIS A C    1 
ATOM   5573 O O    . HIS A 1 367 ? 93.653  105.911 95.008  1.00 83.15  ? 367 HIS A O    1 
ATOM   5574 C CB   . HIS A 1 367 ? 95.297  108.120 94.251  1.00 83.15  ? 367 HIS A CB   1 
ATOM   5575 C CG   . HIS A 1 367 ? 94.426  107.951 93.047  1.00 83.15  ? 367 HIS A CG   1 
ATOM   5576 N ND1  . HIS A 1 367 ? 94.225  106.730 92.441  1.00 83.15  ? 367 HIS A ND1  1 
ATOM   5577 C CD2  . HIS A 1 367 ? 93.712  108.849 92.329  1.00 83.15  ? 367 HIS A CD2  1 
ATOM   5578 C CE1  . HIS A 1 367 ? 93.421  106.882 91.404  1.00 83.15  ? 367 HIS A CE1  1 
ATOM   5579 N NE2  . HIS A 1 367 ? 93.095  108.159 91.314  1.00 83.15  ? 367 HIS A NE2  1 
ATOM   5580 H H    . HIS A 1 367 ? 96.192  108.648 96.467  1.00 83.15  ? 367 HIS A H    1 
ATOM   5581 H HA   . HIS A 1 367 ? 93.720  108.559 95.481  1.00 83.15  ? 367 HIS A HA   1 
ATOM   5582 H HB2  . HIS A 1 367 ? 95.729  108.986 94.183  1.00 83.15  ? 367 HIS A HB2  1 
ATOM   5583 H HB3  . HIS A 1 367 ? 95.966  107.418 94.235  1.00 83.15  ? 367 HIS A HB3  1 
ATOM   5584 H HD1  . HIS A 1 367 ? 94.569  105.986 92.699  1.00 83.15  ? 367 HIS A HD1  1 
ATOM   5585 H HD2  . HIS A 1 367 ? 93.649  109.762 92.493  1.00 83.15  ? 367 HIS A HD2  1 
ATOM   5586 H HE1  . HIS A 1 367 ? 93.133  106.205 90.834  1.00 83.15  ? 367 HIS A HE1  1 
ATOM   5587 N N    . MET A 1 368 ? 94.389  106.142 97.120  1.00 84.54  ? 368 MET A N    1 
ATOM   5588 C CA   . MET A 1 368 ? 94.059  104.772 97.485  1.00 84.54  ? 368 MET A CA   1 
ATOM   5589 C C    . MET A 1 368 ? 92.545  104.579 97.517  1.00 84.54  ? 368 MET A C    1 
ATOM   5590 O O    . MET A 1 368 ? 91.760  105.511 97.318  1.00 84.54  ? 368 MET A O    1 
ATOM   5591 C CB   . MET A 1 368 ? 94.661  104.419 98.843  1.00 84.54  ? 368 MET A CB   1 
ATOM   5592 C CG   . MET A 1 368 ? 96.150  104.126 98.823  1.00 84.54  ? 368 MET A CG   1 
ATOM   5593 S SD   . MET A 1 368 ? 96.606  102.748 97.753  1.00 84.54  ? 368 MET A SD   1 
ATOM   5594 C CE   . MET A 1 368 ? 95.582  101.434 98.409  1.00 84.54  ? 368 MET A CE   1 
ATOM   5595 H H    . MET A 1 368 ? 94.736  106.601 97.759  1.00 84.54  ? 368 MET A H    1 
ATOM   5596 H HA   . MET A 1 368 ? 94.435  104.173 96.822  1.00 84.54  ? 368 MET A HA   1 
ATOM   5597 H HB2  . MET A 1 368 ? 94.520  105.167 99.445  1.00 84.54  ? 368 MET A HB2  1 
ATOM   5598 H HB3  . MET A 1 368 ? 94.211  103.635 99.193  1.00 84.54  ? 368 MET A HB3  1 
ATOM   5599 H HG2  . MET A 1 368 ? 96.615  104.912 98.506  1.00 84.54  ? 368 MET A HG2  1 
ATOM   5600 H HG3  . MET A 1 368 ? 96.440  103.912 99.723  1.00 84.54  ? 368 MET A HG3  1 
ATOM   5601 H HE1  . MET A 1 368 ? 95.840  100.597 97.993  1.00 84.54  ? 368 MET A HE1  1 
ATOM   5602 H HE2  . MET A 1 368 ? 95.711  101.382 99.369  1.00 84.54  ? 368 MET A HE2  1 
ATOM   5603 H HE3  . MET A 1 368 ? 94.653  101.629 98.211  1.00 84.54  ? 368 MET A HE3  1 
ATOM   5604 N N    . GLY A 1 369 ? 92.135  103.338 97.773  1.00 88.34  ? 369 GLY A N    1 
ATOM   5605 C CA   . GLY A 1 369 ? 90.734  103.008 97.905  1.00 88.34  ? 369 GLY A CA   1 
ATOM   5606 C C    . GLY A 1 369 ? 90.178  103.387 99.264  1.00 88.34  ? 369 GLY A C    1 
ATOM   5607 O O    . GLY A 1 369 ? 90.858  103.945 100.125 1.00 88.34  ? 369 GLY A O    1 
ATOM   5608 H H    . GLY A 1 369 ? 92.662  102.667 97.875  1.00 88.34  ? 369 GLY A H    1 
ATOM   5609 H HA2  . GLY A 1 369 ? 90.227  103.476 97.224  1.00 88.34  ? 369 GLY A HA2  1 
ATOM   5610 H HA3  . GLY A 1 369 ? 90.613  102.055 97.778  1.00 88.34  ? 369 GLY A HA3  1 
ATOM   5611 N N    . ALA A 1 370 ? 88.901  103.067 99.453  1.00 90.69  ? 370 ALA A N    1 
ATOM   5612 C CA   . ALA A 1 370 ? 88.215  103.428 100.685 1.00 90.69  ? 370 ALA A CA   1 
ATOM   5613 C C    . ALA A 1 370 ? 88.864  102.745 101.882 1.00 90.69  ? 370 ALA A C    1 
ATOM   5614 O O    . ALA A 1 370 ? 89.348  101.614 101.789 1.00 90.69  ? 370 ALA A O    1 
ATOM   5615 C CB   . ALA A 1 370 ? 86.737  103.049 100.599 1.00 90.69  ? 370 ALA A CB   1 
ATOM   5616 H H    . ALA A 1 370 ? 88.413  102.643 98.885  1.00 90.69  ? 370 ALA A H    1 
ATOM   5617 H HA   . ALA A 1 370 ? 88.276  104.388 100.814 1.00 90.69  ? 370 ALA A HA   1 
ATOM   5618 H HB1  . ALA A 1 370 ? 86.300  103.296 101.429 1.00 90.69  ? 370 ALA A HB1  1 
ATOM   5619 H HB2  . ALA A 1 370 ? 86.333  103.526 99.857  1.00 90.69  ? 370 ALA A HB2  1 
ATOM   5620 H HB3  . ALA A 1 370 ? 86.664  102.093 100.457 1.00 90.69  ? 370 ALA A HB3  1 
ATOM   5621 N N    . THR A 1 371 ? 88.873  103.446 103.013 1.00 88.08  ? 371 THR A N    1 
ATOM   5622 C CA   . THR A 1 371 ? 89.473  102.910 104.226 1.00 88.08  ? 371 THR A CA   1 
ATOM   5623 C C    . THR A 1 371 ? 88.656  101.738 104.756 1.00 88.08  ? 371 THR A C    1 
ATOM   5624 O O    . THR A 1 371 ? 87.424  101.736 104.689 1.00 88.08  ? 371 THR A O    1 
ATOM   5625 C CB   . THR A 1 371 ? 89.574  103.999 105.294 1.00 88.08  ? 371 THR A CB   1 
ATOM   5626 H H    . THR A 1 371 ? 88.535  104.232 103.103 1.00 88.08  ? 371 THR A H    1 
ATOM   5627 H HA   . THR A 1 371 ? 90.368  102.594 104.029 1.00 88.08  ? 371 THR A HA   1 
ATOM   5628 N N    . GLY A 1 372 ? 89.352  100.737 105.287 1.00 73.74  ? 372 GLY A N    1 
ATOM   5629 C CA   . GLY A 1 372 ? 88.684  99.579  105.839 1.00 73.74  ? 372 GLY A CA   1 
ATOM   5630 C C    . GLY A 1 372 ? 88.001  99.887  107.158 1.00 73.74  ? 372 GLY A C    1 
ATOM   5631 O O    . GLY A 1 372 ? 88.211  100.926 107.785 1.00 73.74  ? 372 GLY A O    1 
ATOM   5632 H H    . GLY A 1 372 ? 90.210  100.712 105.339 1.00 73.74  ? 372 GLY A H    1 
ATOM   5633 H HA2  . GLY A 1 372 ? 88.016  99.260  105.213 1.00 73.74  ? 372 GLY A HA2  1 
ATOM   5634 H HA3  . GLY A 1 372 ? 89.331  98.871  105.986 1.00 73.74  ? 372 GLY A HA3  1 
ATOM   5635 N N    . GLY A 1 373 ? 87.158  98.946  107.587 1.00 67.35  ? 373 GLY A N    1 
ATOM   5636 C CA   . GLY A 1 373 ? 86.424  99.142  108.827 1.00 67.35  ? 373 GLY A CA   1 
ATOM   5637 C C    . GLY A 1 373 ? 87.343  99.328  110.019 1.00 67.35  ? 373 GLY A C    1 
ATOM   5638 O O    . GLY A 1 373 ? 87.176  100.258 110.811 1.00 67.35  ? 373 GLY A O    1 
ATOM   5639 H H    . GLY A 1 373 ? 86.995  98.204  107.184 1.00 67.35  ? 373 GLY A H    1 
ATOM   5640 H HA2  . GLY A 1 373 ? 85.860  99.926  108.747 1.00 67.35  ? 373 GLY A HA2  1 
ATOM   5641 H HA3  . GLY A 1 373 ? 85.858  98.372  108.992 1.00 67.35  ? 373 GLY A HA3  1 
ATOM   5642 N N    . ASN A 1 374 ? 88.331  98.448  110.157 1.00 55.24  ? 374 ASN A N    1 
ATOM   5643 C CA   . ASN A 1 374 ? 89.302  98.526  111.243 1.00 55.24  ? 374 ASN A CA   1 
ATOM   5644 C C    . ASN A 1 374 ? 90.491  99.357  110.779 1.00 55.24  ? 374 ASN A C    1 
ATOM   5645 O O    . ASN A 1 374 ? 91.230  98.949  109.878 1.00 55.24  ? 374 ASN A O    1 
ATOM   5646 C CB   . ASN A 1 374 ? 89.747  97.130  111.671 1.00 55.24  ? 374 ASN A CB   1 
ATOM   5647 C CG   . ASN A 1 374 ? 88.715  96.426  112.526 1.00 55.24  ? 374 ASN A CG   1 
ATOM   5648 O OD1  . ASN A 1 374 ? 87.922  97.067  113.214 1.00 55.24  ? 374 ASN A OD1  1 
ATOM   5649 N ND2  . ASN A 1 374 ? 88.723  95.098  112.493 1.00 55.24  ? 374 ASN A ND2  1 
ATOM   5650 H H    . ASN A 1 374 ? 88.460  97.786  109.624 1.00 55.24  ? 374 ASN A H    1 
ATOM   5651 H HA   . ASN A 1 374 ? 88.899  98.968  112.006 1.00 55.24  ? 374 ASN A HA   1 
ATOM   5652 H HB2  . ASN A 1 374 ? 89.899  96.591  110.879 1.00 55.24  ? 374 ASN A HB2  1 
ATOM   5653 H HB3  . ASN A 1 374 ? 90.566  97.203  112.186 1.00 55.24  ? 374 ASN A HB3  1 
ATOM   5654 H HD21 . ASN A 1 374 ? 88.156  94.654  112.963 1.00 55.24  ? 374 ASN A HD21 1 
ATOM   5655 H HD22 . ASN A 1 374 ? 89.294  94.684  112.001 1.00 55.24  ? 374 ASN A HD22 1 
ATOM   5656 N N    . LEU A 1 375 ? 90.671  100.530 111.388 1.00 49.55  ? 375 LEU A N    1 
ATOM   5657 C CA   . LEU A 1 375 ? 91.847  101.338 111.086 1.00 49.55  ? 375 LEU A CA   1 
ATOM   5658 C C    . LEU A 1 375 ? 93.126  100.586 111.428 1.00 49.55  ? 375 LEU A C    1 
ATOM   5659 O O    . LEU A 1 375 ? 94.110  100.641 110.679 1.00 49.55  ? 375 LEU A O    1 
ATOM   5660 C CB   . LEU A 1 375 ? 91.785  102.660 111.850 1.00 49.55  ? 375 LEU A CB   1 
ATOM   5661 C CG   . LEU A 1 375 ? 92.963  103.617 111.650 1.00 49.55  ? 375 LEU A CG   1 
ATOM   5662 C CD1  . LEU A 1 375 ? 93.094  104.025 110.191 1.00 49.55  ? 375 LEU A CD1  1 
ATOM   5663 C CD2  . LEU A 1 375 ? 92.802  104.842 112.535 1.00 49.55  ? 375 LEU A CD2  1 
ATOM   5664 H H    . LEU A 1 375 ? 90.136  100.874 111.967 1.00 49.55  ? 375 LEU A H    1 
ATOM   5665 H HA   . LEU A 1 375 ? 91.858  101.536 110.137 1.00 49.55  ? 375 LEU A HA   1 
ATOM   5666 H HB2  . LEU A 1 375 ? 90.981  103.131 111.578 1.00 49.55  ? 375 LEU A HB2  1 
ATOM   5667 H HB3  . LEU A 1 375 ? 91.735  102.460 112.798 1.00 49.55  ? 375 LEU A HB3  1 
ATOM   5668 H HG   . LEU A 1 375 ? 93.783  103.170 111.910 1.00 49.55  ? 375 LEU A HG   1 
ATOM   5669 H HD11 . LEU A 1 375 ? 93.812  104.673 110.108 1.00 49.55  ? 375 LEU A HD11 1 
ATOM   5670 H HD12 . LEU A 1 375 ? 93.295  103.240 109.658 1.00 49.55  ? 375 LEU A HD12 1 
ATOM   5671 H HD13 . LEU A 1 375 ? 92.258  104.420 109.898 1.00 49.55  ? 375 LEU A HD13 1 
ATOM   5672 H HD21 . LEU A 1 375 ? 93.555  105.436 112.391 1.00 49.55  ? 375 LEU A HD21 1 
ATOM   5673 H HD22 . LEU A 1 375 ? 91.975  105.292 112.302 1.00 49.55  ? 375 LEU A HD22 1 
ATOM   5674 H HD23 . LEU A 1 375 ? 92.775  104.560 113.463 1.00 49.55  ? 375 LEU A HD23 1 
ATOM   5675 N N    . TYR A 1 376 ? 93.131  99.877  112.559 1.00 44.86  ? 376 TYR A N    1 
ATOM   5676 C CA   . TYR A 1 376 ? 94.334  99.168  112.981 1.00 44.86  ? 376 TYR A CA   1 
ATOM   5677 C C    . TYR A 1 376 ? 94.729  98.099  111.971 1.00 44.86  ? 376 TYR A C    1 
ATOM   5678 O O    . TYR A 1 376 ? 95.910  97.954  111.645 1.00 44.86  ? 376 TYR A O    1 
ATOM   5679 C CB   . TYR A 1 376 ? 94.118  98.548  114.360 1.00 44.86  ? 376 TYR A CB   1 
ATOM   5680 C CG   . TYR A 1 376 ? 93.868  99.560  115.453 1.00 44.86  ? 376 TYR A CG   1 
ATOM   5681 C CD1  . TYR A 1 376 ? 92.621  100.146 115.608 1.00 44.86  ? 376 TYR A CD1  1 
ATOM   5682 C CD2  . TYR A 1 376 ? 94.875  99.925  116.332 1.00 44.86  ? 376 TYR A CD2  1 
ATOM   5683 C CE1  . TYR A 1 376 ? 92.384  101.069 116.603 1.00 44.86  ? 376 TYR A CE1  1 
ATOM   5684 C CE2  . TYR A 1 376 ? 94.647  100.846 117.333 1.00 44.86  ? 376 TYR A CE2  1 
ATOM   5685 C CZ   . TYR A 1 376 ? 93.399  101.416 117.463 1.00 44.86  ? 376 TYR A CZ   1 
ATOM   5686 O OH   . TYR A 1 376 ? 93.161  102.337 118.457 1.00 44.86  ? 376 TYR A OH   1 
ATOM   5687 H H    . TYR A 1 376 ? 92.459  99.791  113.086 1.00 44.86  ? 376 TYR A H    1 
ATOM   5688 H HA   . TYR A 1 376 ? 95.066  99.801  113.048 1.00 44.86  ? 376 TYR A HA   1 
ATOM   5689 H HB2  . TYR A 1 376 ? 93.350  97.958  114.320 1.00 44.86  ? 376 TYR A HB2  1 
ATOM   5690 H HB3  . TYR A 1 376 ? 94.909  98.041  114.601 1.00 44.86  ? 376 TYR A HB3  1 
ATOM   5691 H HD1  . TYR A 1 376 ? 91.932  99.914  115.027 1.00 44.86  ? 376 TYR A HD1  1 
ATOM   5692 H HD2  . TYR A 1 376 ? 95.718  99.542  116.246 1.00 44.86  ? 376 TYR A HD2  1 
ATOM   5693 H HE1  . TYR A 1 376 ? 91.543  101.454 116.693 1.00 44.86  ? 376 TYR A HE1  1 
ATOM   5694 H HE2  . TYR A 1 376 ? 95.332  101.083 117.916 1.00 44.86  ? 376 TYR A HE2  1 
ATOM   5695 H HH   . TYR A 1 376 ? 93.860  102.464 118.905 1.00 44.86  ? 376 TYR A HH   1 
ATOM   5696 N N    . LEU A 1 377 ? 93.756  97.337  111.466 1.00 47.71  ? 377 LEU A N    1 
ATOM   5697 C CA   . LEU A 1 377 ? 94.070  96.305  110.481 1.00 47.71  ? 377 LEU A CA   1 
ATOM   5698 C C    . LEU A 1 377 ? 94.599  96.918  109.190 1.00 47.71  ? 377 LEU A C    1 
ATOM   5699 O O    . LEU A 1 377 ? 95.529  96.381  108.576 1.00 47.71  ? 377 LEU A O    1 
ATOM   5700 C CB   . LEU A 1 377 ? 92.835  95.449  110.189 1.00 30.00  ? 377 LEU A CB   1 
ATOM   5701 C CG   . LEU A 1 377 ? 92.579  94.281  111.146 1.00 30.00  ? 377 LEU A CG   1 
ATOM   5702 C CD1  . LEU A 1 377 ? 92.246  94.793  112.539 1.00 30.00  ? 377 LEU A CD1  1 
ATOM   5703 C CD2  . LEU A 1 377 ? 91.469  93.386  110.618 1.00 30.00  ? 377 LEU A CD2  1 
ATOM   5704 H H    . LEU A 1 377 ? 92.924  97.396  111.674 1.00 47.71  ? 377 LEU A H    1 
ATOM   5705 H HA   . LEU A 1 377 ? 94.759  95.725  110.841 1.00 47.71  ? 377 LEU A HA   1 
ATOM   5706 N N    . ASP A 1 378 ? 94.013  98.035  108.755 1.00 49.18  ? 378 ASP A N    1 
ATOM   5707 C CA   . ASP A 1 378 ? 94.505  98.697  107.553 1.00 49.18  ? 378 ASP A CA   1 
ATOM   5708 C C    . ASP A 1 378 ? 95.942  99.163  107.736 1.00 49.18  ? 378 ASP A C    1 
ATOM   5709 O O    . ASP A 1 378 ? 96.781  98.985  106.844 1.00 49.18  ? 378 ASP A O    1 
ATOM   5710 C CB   . ASP A 1 378 ? 93.608  99.882  107.189 1.00 30.00  ? 378 ASP A CB   1 
ATOM   5711 C CG   . ASP A 1 378 ? 94.021  100.547 105.890 1.00 30.00  ? 378 ASP A CG   1 
ATOM   5712 O OD1  . ASP A 1 378 ? 94.992  100.076 105.262 1.00 30.00  ? 378 ASP A OD1  1 
ATOM   5713 O OD2  . ASP A 1 378 ? 93.433  101.544 105.420 1.00 30.00  ? 378 ASP A OD2  1 
ATOM   5714 H H    . ASP A 1 378 ? 93.343  98.420  109.132 1.00 49.18  ? 378 ASP A H    1 
ATOM   5715 H HA   . ASP A 1 378 ? 94.484  98.068  106.815 1.00 49.18  ? 378 ASP A HA   1 
ATOM   5716 N N    . PHE A 1 379 ? 96.247  99.761  108.889 1.00 43.28  ? 379 PHE A N    1 
ATOM   5717 C CA   . PHE A 1 379 ? 97.614  100.195 109.152 1.00 43.28  ? 379 PHE A CA   1 
ATOM   5718 C C    . PHE A 1 379 ? 98.563  99.006  109.212 1.00 43.28  ? 379 PHE A C    1 
ATOM   5719 O O    . PHE A 1 379 ? 99.698  99.078  108.727 1.00 43.28  ? 379 PHE A O    1 
ATOM   5720 C CB   . PHE A 1 379 ? 97.665  100.987 110.455 1.00 43.28  ? 379 PHE A CB   1 
ATOM   5721 C CG   . PHE A 1 379 ? 98.993  101.618 110.724 1.00 43.28  ? 379 PHE A CG   1 
ATOM   5722 C CD1  . PHE A 1 379 ? 99.469  102.625 109.908 1.00 43.28  ? 379 PHE A CD1  1 
ATOM   5723 C CD2  . PHE A 1 379 ? 99.759  101.214 111.798 1.00 43.28  ? 379 PHE A CD2  1 
ATOM   5724 C CE1  . PHE A 1 379 ? 100.687 103.211 110.152 1.00 43.28  ? 379 PHE A CE1  1 
ATOM   5725 C CE2  . PHE A 1 379 ? 100.978 101.798 112.048 1.00 43.28  ? 379 PHE A CE2  1 
ATOM   5726 C CZ   . PHE A 1 379 ? 101.444 102.798 111.224 1.00 43.28  ? 379 PHE A CZ   1 
ATOM   5727 H H    . PHE A 1 379 ? 95.689  99.923  109.523 1.00 43.28  ? 379 PHE A H    1 
ATOM   5728 H HA   . PHE A 1 379 ? 97.906  100.777 108.433 1.00 43.28  ? 379 PHE A HA   1 
ATOM   5729 H HB2  . PHE A 1 379 ? 97.003  101.695 110.415 1.00 43.28  ? 379 PHE A HB2  1 
ATOM   5730 H HB3  . PHE A 1 379 ? 97.464  100.391 111.193 1.00 43.28  ? 379 PHE A HB3  1 
ATOM   5731 H HD1  . PHE A 1 379 ? 98.961  102.906 109.181 1.00 43.28  ? 379 PHE A HD1  1 
ATOM   5732 H HD2  . PHE A 1 379 ? 99.449  100.539 112.357 1.00 43.28  ? 379 PHE A HD2  1 
ATOM   5733 H HE1  . PHE A 1 379 ? 100.999 103.887 109.594 1.00 43.28  ? 379 PHE A HE1  1 
ATOM   5734 H HE2  . PHE A 1 379 ? 101.489 101.518 112.773 1.00 43.28  ? 379 PHE A HE2  1 
ATOM   5735 H HZ   . PHE A 1 379 ? 102.268 103.194 111.391 1.00 43.28  ? 379 PHE A HZ   1 
ATOM   5736 N N    . PHE A 1 380 ? 98.112  97.902  109.806 1.00 45.79  ? 380 PHE A N    1 
ATOM   5737 C CA   . PHE A 1 380 ? 98.932  96.700  109.866 1.00 45.79  ? 380 PHE A CA   1 
ATOM   5738 C C    . PHE A 1 380 ? 99.264  96.195  108.469 1.00 45.79  ? 380 PHE A C    1 
ATOM   5739 O O    . PHE A 1 380 ? 100.413 95.841  108.188 1.00 45.79  ? 380 PHE A O    1 
ATOM   5740 C CB   . PHE A 1 380 ? 98.198  95.631  110.675 1.00 45.79  ? 380 PHE A CB   1 
ATOM   5741 C CG   . PHE A 1 380 ? 98.873  94.294  110.682 1.00 45.79  ? 380 PHE A CG   1 
ATOM   5742 C CD1  . PHE A 1 380 ? 99.818  93.989  111.640 1.00 45.79  ? 380 PHE A CD1  1 
ATOM   5743 C CD2  . PHE A 1 380 ? 98.542  93.334  109.746 1.00 45.79  ? 380 PHE A CD2  1 
ATOM   5744 C CE1  . PHE A 1 380 ? 100.432 92.759  111.654 1.00 45.79  ? 380 PHE A CE1  1 
ATOM   5745 C CE2  . PHE A 1 380 ? 99.152  92.102  109.756 1.00 45.79  ? 380 PHE A CE2  1 
ATOM   5746 C CZ   . PHE A 1 380 ? 100.098 91.814  110.711 1.00 45.79  ? 380 PHE A CZ   1 
ATOM   5747 H H    . PHE A 1 380 ? 97.341  97.827  110.179 1.00 45.79  ? 380 PHE A H    1 
ATOM   5748 H HA   . PHE A 1 380 ? 99.765  96.904  110.319 1.00 45.79  ? 380 PHE A HA   1 
ATOM   5749 H HB2  . PHE A 1 380 ? 98.128  95.931  111.594 1.00 45.79  ? 380 PHE A HB2  1 
ATOM   5750 H HB3  . PHE A 1 380 ? 97.311  95.512  110.301 1.00 45.79  ? 380 PHE A HB3  1 
ATOM   5751 H HD1  . PHE A 1 380 ? 100.048 94.625  112.278 1.00 45.79  ? 380 PHE A HD1  1 
ATOM   5752 H HD2  . PHE A 1 380 ? 97.903  93.525  109.098 1.00 45.79  ? 380 PHE A HD2  1 
ATOM   5753 H HE1  . PHE A 1 380 ? 101.072 92.566  112.300 1.00 45.79  ? 380 PHE A HE1  1 
ATOM   5754 H HE2  . PHE A 1 380 ? 98.925  91.465  109.118 1.00 45.79  ? 380 PHE A HE2  1 
ATOM   5755 H HZ   . PHE A 1 380 ? 100.513 90.981  110.719 1.00 45.79  ? 380 PHE A HZ   1 
ATOM   5756 N N    . TYR A 1 381 ? 98.272  96.159  107.576 1.00 50.19  ? 381 TYR A N    1 
ATOM   5757 C CA   . TYR A 1 381 ? 98.534  95.732  106.203 1.00 50.19  ? 381 TYR A CA   1 
ATOM   5758 C C    . TYR A 1 381 ? 99.483  96.694  105.499 1.00 50.19  ? 381 TYR A C    1 
ATOM   5759 O O    . TYR A 1 381 ? 100.402 96.266  104.787 1.00 50.19  ? 381 TYR A O    1 
ATOM   5760 C CB   . TYR A 1 381 ? 97.225  95.624  105.421 1.00 50.19  ? 381 TYR A CB   1 
ATOM   5761 C CG   . TYR A 1 381 ? 96.235  94.632  105.985 1.00 50.19  ? 381 TYR A CG   1 
ATOM   5762 C CD1  . TYR A 1 381 ? 96.660  93.451  106.576 1.00 50.19  ? 381 TYR A CD1  1 
ATOM   5763 C CD2  . TYR A 1 381 ? 94.871  94.879  105.926 1.00 50.19  ? 381 TYR A CD2  1 
ATOM   5764 C CE1  . TYR A 1 381 ? 95.756  92.545  107.090 1.00 50.19  ? 381 TYR A CE1  1 
ATOM   5765 C CE2  . TYR A 1 381 ? 93.961  93.981  106.439 1.00 50.19  ? 381 TYR A CE2  1 
ATOM   5766 C CZ   . TYR A 1 381 ? 94.408  92.816  107.019 1.00 50.19  ? 381 TYR A CZ   1 
ATOM   5767 O OH   . TYR A 1 381 ? 93.502  91.916  107.532 1.00 50.19  ? 381 TYR A OH   1 
ATOM   5768 H H    . TYR A 1 381 ? 97.454  96.371  107.737 1.00 50.19  ? 381 TYR A H    1 
ATOM   5769 H HA   . TYR A 1 381 ? 98.955  94.859  106.217 1.00 50.19  ? 381 TYR A HA   1 
ATOM   5770 H HB2  . TYR A 1 381 ? 96.796  96.494  105.412 1.00 50.19  ? 381 TYR A HB2  1 
ATOM   5771 H HB3  . TYR A 1 381 ? 97.428  95.351  104.513 1.00 50.19  ? 381 TYR A HB3  1 
ATOM   5772 H HD1  . TYR A 1 381 ? 97.570  93.266  106.625 1.00 50.19  ? 381 TYR A HD1  1 
ATOM   5773 H HD2  . TYR A 1 381 ? 94.566  95.666  105.534 1.00 50.19  ? 381 TYR A HD2  1 
ATOM   5774 H HE1  . TYR A 1 381 ? 96.055  91.758  107.484 1.00 50.19  ? 381 TYR A HE1  1 
ATOM   5775 H HE2  . TYR A 1 381 ? 93.049  94.161  106.392 1.00 50.19  ? 381 TYR A HE2  1 
ATOM   5776 H HH   . TYR A 1 381 ? 92.730  92.247  107.521 1.00 50.19  ? 381 TYR A HH   1 
ATOM   5777 N N    . SER A 1 382 ? 99.266  98.000  105.672 1.00 50.03  ? 382 SER A N    1 
ATOM   5778 C CA   . SER A 1 382 ? 100.118 98.979  105.009 1.00 50.03  ? 382 SER A CA   1 
ATOM   5779 C C    . SER A 1 382 ? 101.558 98.870  105.484 1.00 50.03  ? 382 SER A C    1 
ATOM   5780 O O    . SER A 1 382 ? 102.487 99.120  104.710 1.00 50.03  ? 382 SER A O    1 
ATOM   5781 C CB   . SER A 1 382 ? 99.584  100.390 105.252 1.00 50.03  ? 382 SER A CB   1 
ATOM   5782 O OG   . SER A 1 382 ? 100.402 101.357 104.619 1.00 50.03  ? 382 SER A OG   1 
ATOM   5783 H H    . SER A 1 382 ? 98.642  98.336  106.160 1.00 50.03  ? 382 SER A H    1 
ATOM   5784 H HA   . SER A 1 382 ? 100.103 98.813  104.054 1.00 50.03  ? 382 SER A HA   1 
ATOM   5785 H HB2  . SER A 1 382 ? 98.685  100.453 104.891 1.00 50.03  ? 382 SER A HB2  1 
ATOM   5786 H HB3  . SER A 1 382 ? 99.571  100.563 106.206 1.00 50.03  ? 382 SER A HB3  1 
ATOM   5787 H HG   . SER A 1 382 ? 100.061 102.120 104.700 1.00 50.03  ? 382 SER A HG   1 
ATOM   5788 N N    . ALA A 1 383 ? 101.765 98.515  106.751 1.00 46.37  ? 383 ALA A N    1 
ATOM   5789 C CA   . ALA A 1 383 ? 103.125 98.305  107.235 1.00 46.37  ? 383 ALA A CA   1 
ATOM   5790 C C    . ALA A 1 383 ? 103.697 96.994  106.716 1.00 46.37  ? 383 ALA A C    1 
ATOM   5791 O O    . ALA A 1 383 ? 104.861 96.937  106.308 1.00 46.37  ? 383 ALA A O    1 
ATOM   5792 C CB   . ALA A 1 383 ? 103.151 98.330  108.761 1.00 46.37  ? 383 ALA A CB   1 
ATOM   5793 H H    . ALA A 1 383 ? 101.149 98.391  107.338 1.00 46.37  ? 383 ALA A H    1 
ATOM   5794 H HA   . ALA A 1 383 ? 103.689 99.026  106.914 1.00 46.37  ? 383 ALA A HA   1 
ATOM   5795 H HB1  . ALA A 1 383 ? 104.062 98.191  109.063 1.00 46.37  ? 383 ALA A HB1  1 
ATOM   5796 H HB2  . ALA A 1 383 ? 102.829 99.193  109.068 1.00 46.37  ? 383 ALA A HB2  1 
ATOM   5797 H HB3  . ALA A 1 383 ? 102.578 97.624  109.098 1.00 46.37  ? 383 ALA A HB3  1 
ATOM   5798 N N    . LEU A 1 384 ? 102.893 95.930  106.719 1.00 48.53  ? 384 LEU A N    1 
ATOM   5799 C CA   . LEU A 1 384 ? 103.386 94.619  106.318 1.00 48.53  ? 384 LEU A CA   1 
ATOM   5800 C C    . LEU A 1 384 ? 103.733 94.557  104.841 1.00 48.53  ? 384 LEU A C    1 
ATOM   5801 O O    . LEU A 1 384 ? 104.547 93.718  104.447 1.00 48.53  ? 384 LEU A O    1 
ATOM   5802 C CB   . LEU A 1 384 ? 102.351 93.545  106.647 1.00 48.53  ? 384 LEU A CB   1 
ATOM   5803 C CG   . LEU A 1 384 ? 102.747 92.110  106.298 1.00 48.53  ? 384 LEU A CG   1 
ATOM   5804 C CD1  . LEU A 1 384 ? 102.256 91.158  107.370 1.00 48.53  ? 384 LEU A CD1  1 
ATOM   5805 C CD2  . LEU A 1 384 ? 102.188 91.705  104.944 1.00 48.53  ? 384 LEU A CD2  1 
ATOM   5806 H H    . LEU A 1 384 ? 102.063 95.943  106.946 1.00 48.53  ? 384 LEU A H    1 
ATOM   5807 H HA   . LEU A 1 384 ? 104.191 94.421  106.820 1.00 48.53  ? 384 LEU A HA   1 
ATOM   5808 H HB2  . LEU A 1 384 ? 102.172 93.574  107.600 1.00 48.53  ? 384 LEU A HB2  1 
ATOM   5809 H HB3  . LEU A 1 384 ? 101.537 93.747  106.160 1.00 48.53  ? 384 LEU A HB3  1 
ATOM   5810 H HG   . LEU A 1 384 ? 103.714 92.047  106.258 1.00 48.53  ? 384 LEU A HG   1 
ATOM   5811 H HD11 . LEU A 1 384 ? 102.508 90.253  107.129 1.00 48.53  ? 384 LEU A HD11 1 
ATOM   5812 H HD12 . LEU A 1 384 ? 102.661 91.400  108.218 1.00 48.53  ? 384 LEU A HD12 1 
ATOM   5813 H HD13 . LEU A 1 384 ? 101.290 91.226  107.433 1.00 48.53  ? 384 LEU A HD13 1 
ATOM   5814 H HD21 . LEU A 1 384 ? 102.407 90.775  104.781 1.00 48.53  ? 384 LEU A HD21 1 
ATOM   5815 H HD22 . LEU A 1 384 ? 101.225 91.821  104.954 1.00 48.53  ? 384 LEU A HD22 1 
ATOM   5816 H HD23 . LEU A 1 384 ? 102.580 92.261  104.253 1.00 48.53  ? 384 LEU A HD23 1 
ATOM   5817 N N    . VAL A 1 385 ? 103.134 95.412  104.011 1.00 52.39  ? 385 VAL A N    1 
ATOM   5818 C CA   . VAL A 1 385 ? 103.470 95.407  102.594 1.00 52.39  ? 385 VAL A CA   1 
ATOM   5819 C C    . VAL A 1 385 ? 104.929 95.765  102.343 1.00 52.39  ? 385 VAL A C    1 
ATOM   5820 O O    . VAL A 1 385 ? 105.404 95.624  101.214 1.00 52.39  ? 385 VAL A O    1 
ATOM   5821 C CB   . VAL A 1 385 ? 102.550 96.370  101.812 1.00 52.39  ? 385 VAL A CB   1 
ATOM   5822 C CG1  . VAL A 1 385 ? 103.050 97.802  101.923 1.00 52.39  ? 385 VAL A CG1  1 
ATOM   5823 C CG2  . VAL A 1 385 ? 102.455 95.945  100.356 1.00 52.39  ? 385 VAL A CG2  1 
ATOM   5824 H H    . VAL A 1 385 ? 102.543 95.993  104.241 1.00 52.39  ? 385 VAL A H    1 
ATOM   5825 H HA   . VAL A 1 385 ? 103.323 94.514  102.246 1.00 52.39  ? 385 VAL A HA   1 
ATOM   5826 H HB   . VAL A 1 385 ? 101.659 96.334  102.192 1.00 52.39  ? 385 VAL A HB   1 
ATOM   5827 H HG11 . VAL A 1 385 ? 102.317 98.407  101.725 1.00 52.39  ? 385 VAL A HG11 1 
ATOM   5828 H HG12 . VAL A 1 385 ? 103.370 97.955  102.825 1.00 52.39  ? 385 VAL A HG12 1 
ATOM   5829 H HG13 . VAL A 1 385 ? 103.771 97.938  101.289 1.00 52.39  ? 385 VAL A HG13 1 
ATOM   5830 H HG21 . VAL A 1 385 ? 101.850 96.545  99.892  1.00 52.39  ? 385 VAL A HG21 1 
ATOM   5831 H HG22 . VAL A 1 385 ? 103.337 95.991  99.956  1.00 52.39  ? 385 VAL A HG22 1 
ATOM   5832 H HG23 . VAL A 1 385 ? 102.118 95.037  100.314 1.00 52.39  ? 385 VAL A HG23 1 
ATOM   5833 N N    . GLU A 1 386 ? 105.652 96.228  103.366 1.00 49.76  ? 386 GLU A N    1 
ATOM   5834 C CA   . GLU A 1 386 ? 107.038 96.641  103.176 1.00 49.76  ? 386 GLU A CA   1 
ATOM   5835 C C    . GLU A 1 386 ? 108.019 95.480  103.288 1.00 49.76  ? 386 GLU A C    1 
ATOM   5836 O O    . GLU A 1 386 ? 109.086 95.523  102.668 1.00 49.76  ? 386 GLU A O    1 
ATOM   5837 C CB   . GLU A 1 386 ? 107.416 97.713  104.199 1.00 49.76  ? 386 GLU A CB   1 
ATOM   5838 C CG   . GLU A 1 386 ? 106.591 98.985  104.119 1.00 49.76  ? 386 GLU A CG   1 
ATOM   5839 C CD   . GLU A 1 386 ? 107.095 100.062 105.062 1.00 49.76  ? 386 GLU A CD   1 
ATOM   5840 O OE1  . GLU A 1 386 ? 108.116 99.828  105.743 1.00 49.76  ? 386 GLU A OE1  1 
ATOM   5841 O OE2  . GLU A 1 386 ? 106.471 101.141 105.123 1.00 49.76  ? 386 GLU A OE2  1 
ATOM   5842 H H    . GLU A 1 386 ? 105.366 96.318  104.171 1.00 49.76  ? 386 GLU A H    1 
ATOM   5843 H HA   . GLU A 1 386 ? 107.133 97.026  102.291 1.00 49.76  ? 386 GLU A HA   1 
ATOM   5844 H HB2  . GLU A 1 386 ? 107.302 97.346  105.090 1.00 49.76  ? 386 GLU A HB2  1 
ATOM   5845 H HB3  . GLU A 1 386 ? 108.345 97.956  104.064 1.00 49.76  ? 386 GLU A HB3  1 
ATOM   5846 H HG2  . GLU A 1 386 ? 106.630 99.332  103.215 1.00 49.76  ? 386 GLU A HG2  1 
ATOM   5847 H HG3  . GLU A 1 386 ? 105.673 98.782  104.357 1.00 49.76  ? 386 GLU A HG3  1 
ATOM   5848 N N    . PHE A 1 387 ? 107.691 94.449  104.064 1.00 47.83  ? 387 PHE A N    1 
ATOM   5849 C CA   . PHE A 1 387 ? 108.664 93.389  104.324 1.00 47.83  ? 387 PHE A CA   1 
ATOM   5850 C C    . PHE A 1 387 ? 109.222 92.779  103.049 1.00 47.83  ? 387 PHE A C    1 
ATOM   5851 O O    . PHE A 1 387 ? 110.452 92.636  102.946 1.00 47.83  ? 387 PHE A O    1 
ATOM   5852 C CB   . PHE A 1 387 ? 108.033 92.312  105.209 1.00 47.83  ? 387 PHE A CB   1 
ATOM   5853 C CG   . PHE A 1 387 ? 108.262 92.524  106.672 1.00 47.83  ? 387 PHE A CG   1 
ATOM   5854 C CD1  . PHE A 1 387 ? 109.503 92.287  107.229 1.00 47.83  ? 387 PHE A CD1  1 
ATOM   5855 C CD2  . PHE A 1 387 ? 107.237 92.952  107.493 1.00 47.83  ? 387 PHE A CD2  1 
ATOM   5856 C CE1  . PHE A 1 387 ? 109.718 92.479  108.574 1.00 47.83  ? 387 PHE A CE1  1 
ATOM   5857 C CE2  . PHE A 1 387 ? 107.446 93.145  108.839 1.00 47.83  ? 387 PHE A CE2  1 
ATOM   5858 C CZ   . PHE A 1 387 ? 108.688 92.908  109.380 1.00 47.83  ? 387 PHE A CZ   1 
ATOM   5859 H H    . PHE A 1 387 ? 106.928 94.340  104.446 1.00 47.83  ? 387 PHE A H    1 
ATOM   5860 H HA   . PHE A 1 387 ? 109.410 93.770  104.814 1.00 47.83  ? 387 PHE A HA   1 
ATOM   5861 H HB2  . PHE A 1 387 ? 107.075 92.303  105.059 1.00 47.83  ? 387 PHE A HB2  1 
ATOM   5862 H HB3  . PHE A 1 387 ? 108.411 91.450  104.971 1.00 47.83  ? 387 PHE A HB3  1 
ATOM   5863 H HD1  . PHE A 1 387 ? 110.202 91.998  106.688 1.00 47.83  ? 387 PHE A HD1  1 
ATOM   5864 H HD2  . PHE A 1 387 ? 106.395 93.114  107.131 1.00 47.83  ? 387 PHE A HD2  1 
ATOM   5865 H HE1  . PHE A 1 387 ? 110.558 92.318  108.939 1.00 47.83  ? 387 PHE A HE1  1 
ATOM   5866 H HE2  . PHE A 1 387 ? 106.750 93.435  109.383 1.00 47.83  ? 387 PHE A HE2  1 
ATOM   5867 H HZ   . PHE A 1 387 ? 108.831 93.038  110.289 1.00 47.83  ? 387 PHE A HZ   1 
ATOM   5868 N N    . PRO A 1 388 ? 108.414 92.404  102.057 1.00 53.76  ? 388 PRO A N    1 
ATOM   5869 C CA   . PRO A 1 388 ? 108.994 91.857  100.822 1.00 53.76  ? 388 PRO A CA   1 
ATOM   5870 C C    . PRO A 1 388 ? 109.940 92.816  100.129 1.00 53.76  ? 388 PRO A C    1 
ATOM   5871 O O    . PRO A 1 388 ? 110.837 92.364  99.408  1.00 53.76  ? 388 PRO A O    1 
ATOM   5872 C CB   . PRO A 1 388 ? 107.764 91.557  99.956  1.00 53.76  ? 388 PRO A CB   1 
ATOM   5873 C CG   . PRO A 1 388 ? 106.653 91.386  100.928 1.00 53.76  ? 388 PRO A CG   1 
ATOM   5874 C CD   . PRO A 1 388 ? 106.944 92.337  102.049 1.00 53.76  ? 388 PRO A CD   1 
ATOM   5875 H HA   . PRO A 1 388 ? 109.462 91.028  101.010 1.00 53.76  ? 388 PRO A HA   1 
ATOM   5876 H HB2  . PRO A 1 388 ? 107.590 92.304  99.362  1.00 53.76  ? 388 PRO A HB2  1 
ATOM   5877 H HB3  . PRO A 1 388 ? 107.909 90.741  99.452  1.00 53.76  ? 388 PRO A HB3  1 
ATOM   5878 H HG2  . PRO A 1 388 ? 105.810 91.606  100.501 1.00 53.76  ? 388 PRO A HG2  1 
ATOM   5879 H HG3  . PRO A 1 388 ? 106.643 90.471  101.251 1.00 53.76  ? 388 PRO A HG3  1 
ATOM   5880 H HD2  . PRO A 1 388 ? 106.567 93.210  101.858 1.00 53.76  ? 388 PRO A HD2  1 
ATOM   5881 H HD3  . PRO A 1 388 ? 106.614 91.980  102.887 1.00 53.76  ? 388 PRO A HD3  1 
ATOM   5882 N N    . ALA A 1 389 ? 109.777 94.126  100.322 1.00 53.37  ? 389 ALA A N    1 
ATOM   5883 C CA   . ALA A 1 389 ? 110.703 95.072  99.711  1.00 53.37  ? 389 ALA A CA   1 
ATOM   5884 C C    . ALA A 1 389 ? 112.122 94.852  100.217 1.00 53.37  ? 389 ALA A C    1 
ATOM   5885 O O    . ALA A 1 389 ? 113.079 94.876  99.435  1.00 53.37  ? 389 ALA A O    1 
ATOM   5886 C CB   . ALA A 1 389 ? 110.253 96.504  99.990  1.00 53.37  ? 389 ALA A CB   1 
ATOM   5887 H H    . ALA A 1 389 ? 109.152 94.484  100.792 1.00 53.37  ? 389 ALA A H    1 
ATOM   5888 H HA   . ALA A 1 389 ? 110.703 94.938  98.750  1.00 53.37  ? 389 ALA A HA   1 
ATOM   5889 H HB1  . ALA A 1 389 ? 110.833 97.116  99.510  1.00 53.37  ? 389 ALA A HB1  1 
ATOM   5890 H HB2  . ALA A 1 389 ? 109.337 96.611  99.690  1.00 53.37  ? 389 ALA A HB2  1 
ATOM   5891 H HB3  . ALA A 1 389 ? 110.310 96.674  100.943 1.00 53.37  ? 389 ALA A HB3  1 
ATOM   5892 N N    . ALA A 1 390 ? 112.278 94.632  101.522 1.00 50.27  ? 390 ALA A N    1 
ATOM   5893 C CA   . ALA A 1 390 ? 113.607 94.399  102.071 1.00 50.27  ? 390 ALA A CA   1 
ATOM   5894 C C    . ALA A 1 390 ? 114.235 93.152  101.462 1.00 50.27  ? 390 ALA A C    1 
ATOM   5895 O O    . ALA A 1 390 ? 115.393 93.172  101.032 1.00 50.27  ? 390 ALA A O    1 
ATOM   5896 C CB   . ALA A 1 390 ? 113.532 94.279  103.592 1.00 50.27  ? 390 ALA A CB   1 
ATOM   5897 H H    . ALA A 1 390 ? 111.641 94.613  102.100 1.00 50.27  ? 390 ALA A H    1 
ATOM   5898 H HA   . ALA A 1 390 ? 114.174 95.157  101.861 1.00 50.27  ? 390 ALA A HA   1 
ATOM   5899 H HB1  . ALA A 1 390 ? 114.424 94.131  103.942 1.00 50.27  ? 390 ALA A HB1  1 
ATOM   5900 H HB2  . ALA A 1 390 ? 113.167 95.102  103.955 1.00 50.27  ? 390 ALA A HB2  1 
ATOM   5901 H HB3  . ALA A 1 390 ? 112.957 93.533  103.823 1.00 50.27  ? 390 ALA A HB3  1 
ATOM   5902 N N    . PHE A 1 391 ? 113.480 92.055  101.405 1.00 52.80  ? 391 PHE A N    1 
ATOM   5903 C CA   . PHE A 1 391 ? 114.017 90.820  100.850 1.00 52.80  ? 391 PHE A CA   1 
ATOM   5904 C C    . PHE A 1 391 ? 114.199 90.882  99.341  1.00 52.80  ? 391 PHE A C    1 
ATOM   5905 O O    . PHE A 1 391 ? 114.888 90.021  98.784  1.00 52.80  ? 391 PHE A O    1 
ATOM   5906 C CB   . PHE A 1 391 ? 113.112 89.644  101.216 1.00 52.80  ? 391 PHE A CB   1 
ATOM   5907 C CG   . PHE A 1 391 ? 113.586 88.871  102.410 1.00 52.80  ? 391 PHE A CG   1 
ATOM   5908 C CD1  . PHE A 1 391 ? 113.411 89.366  103.691 1.00 52.80  ? 391 PHE A CD1  1 
ATOM   5909 C CD2  . PHE A 1 391 ? 114.212 87.647  102.249 1.00 52.80  ? 391 PHE A CD2  1 
ATOM   5910 C CE1  . PHE A 1 391 ? 113.852 88.653  104.791 1.00 52.80  ? 391 PHE A CE1  1 
ATOM   5911 C CE2  . PHE A 1 391 ? 114.654 86.929  103.343 1.00 52.80  ? 391 PHE A CE2  1 
ATOM   5912 C CZ   . PHE A 1 391 ? 114.474 87.433  104.616 1.00 52.80  ? 391 PHE A CZ   1 
ATOM   5913 H H    . PHE A 1 391 ? 112.665 92.003  101.676 1.00 52.80  ? 391 PHE A H    1 
ATOM   5914 H HA   . PHE A 1 391 ? 114.888 90.656  101.244 1.00 52.80  ? 391 PHE A HA   1 
ATOM   5915 H HB2  . PHE A 1 391 ? 112.224 89.979  101.413 1.00 52.80  ? 391 PHE A HB2  1 
ATOM   5916 H HB3  . PHE A 1 391 ? 113.073 89.034  100.463 1.00 52.80  ? 391 PHE A HB3  1 
ATOM   5917 H HD1  . PHE A 1 391 ? 112.994 90.188  103.814 1.00 52.80  ? 391 PHE A HD1  1 
ATOM   5918 H HD2  . PHE A 1 391 ? 114.337 87.303  101.394 1.00 52.80  ? 391 PHE A HD2  1 
ATOM   5919 H HE1  . PHE A 1 391 ? 113.729 88.994  105.647 1.00 52.80  ? 391 PHE A HE1  1 
ATOM   5920 H HE2  . PHE A 1 391 ? 115.073 86.108  103.222 1.00 52.80  ? 391 PHE A HE2  1 
ATOM   5921 H HZ   . PHE A 1 391 ? 114.771 86.950  105.353 1.00 52.80  ? 391 PHE A HZ   1 
ATOM   5922 N N    . ILE A 1 392 ? 113.595 91.858  98.668  1.00 52.04  ? 392 ILE A N    1 
ATOM   5923 C CA   . ILE A 1 392 ? 113.892 92.072  97.256  1.00 52.04  ? 392 ILE A CA   1 
ATOM   5924 C C    . ILE A 1 392 ? 115.189 92.849  97.099  1.00 52.04  ? 392 ILE A C    1 
ATOM   5925 O O    . ILE A 1 392 ? 116.061 92.483  96.304  1.00 52.04  ? 392 ILE A O    1 
ATOM   5926 C CB   . ILE A 1 392 ? 112.720 92.794  96.565  1.00 52.04  ? 392 ILE A CB   1 
ATOM   5927 C CG1  . ILE A 1 392 ? 111.567 91.818  96.328  1.00 52.04  ? 392 ILE A CG1  1 
ATOM   5928 C CG2  . ILE A 1 392 ? 113.182 93.418  95.255  1.00 52.04  ? 392 ILE A CG2  1 
ATOM   5929 C CD1  . ILE A 1 392 ? 110.291 92.476  95.849  1.00 52.04  ? 392 ILE A CD1  1 
ATOM   5930 H H    . ILE A 1 392 ? 113.018 92.402  99.000  1.00 52.04  ? 392 ILE A H    1 
ATOM   5931 H HA   . ILE A 1 392 ? 114.006 91.211  96.824  1.00 52.04  ? 392 ILE A HA   1 
ATOM   5932 H HB   . ILE A 1 392 ? 112.408 93.502  97.150  1.00 52.04  ? 392 ILE A HB   1 
ATOM   5933 H HG12 . ILE A 1 392 ? 111.837 91.173  95.656  1.00 52.04  ? 392 ILE A HG12 1 
ATOM   5934 H HG13 . ILE A 1 392 ? 111.369 91.360  97.160  1.00 52.04  ? 392 ILE A HG13 1 
ATOM   5935 H HG21 . ILE A 1 392 ? 112.408 93.648  94.720  1.00 52.04  ? 392 ILE A HG21 1 
ATOM   5936 H HG22 . ILE A 1 392 ? 113.693 94.220  95.446  1.00 52.04  ? 392 ILE A HG22 1 
ATOM   5937 H HG23 . ILE A 1 392 ? 113.733 92.778  94.777  1.00 52.04  ? 392 ILE A HG23 1 
ATOM   5938 H HD11 . ILE A 1 392 ? 109.560 91.845  95.935  1.00 52.04  ? 392 ILE A HD11 1 
ATOM   5939 H HD12 . ILE A 1 392 ? 110.117 93.259  96.394  1.00 52.04  ? 392 ILE A HD12 1 
ATOM   5940 H HD13 . ILE A 1 392 ? 110.396 92.735  94.920  1.00 52.04  ? 392 ILE A HD13 1 
ATOM   5941 N N    . ILE A 1 393 ? 115.333 93.939  97.853  1.00 52.12  ? 393 ILE A N    1 
ATOM   5942 C CA   . ILE A 1 393 ? 116.525 94.772  97.738  1.00 52.12  ? 393 ILE A CA   1 
ATOM   5943 C C    . ILE A 1 393 ? 117.740 94.059  98.314  1.00 52.12  ? 393 ILE A C    1 
ATOM   5944 O O    . ILE A 1 393 ? 118.855 94.185  97.794  1.00 52.12  ? 393 ILE A O    1 
ATOM   5945 C CB   . ILE A 1 393 ? 116.292 96.129  98.424  1.00 52.12  ? 393 ILE A CB   1 
ATOM   5946 C CG1  . ILE A 1 393 ? 117.488 97.046  98.193  1.00 52.12  ? 393 ILE A CG1  1 
ATOM   5947 C CG2  . ILE A 1 393 ? 116.061 95.942  99.910  1.00 52.12  ? 393 ILE A CG2  1 
ATOM   5948 C CD1  . ILE A 1 393 ? 117.285 98.449  98.709  1.00 52.12  ? 393 ILE A CD1  1 
ATOM   5949 H H    . ILE A 1 393 ? 114.759 94.212  98.431  1.00 52.12  ? 393 ILE A H    1 
ATOM   5950 H HA   . ILE A 1 393 ? 116.698 94.940  96.798  1.00 52.12  ? 393 ILE A HA   1 
ATOM   5951 H HB   . ILE A 1 393 ? 115.504 96.542  98.036  1.00 52.12  ? 393 ILE A HB   1 
ATOM   5952 H HG12 . ILE A 1 393 ? 118.265 96.675  98.640  1.00 52.12  ? 393 ILE A HG12 1 
ATOM   5953 H HG13 . ILE A 1 393 ? 117.649 97.100  97.240  1.00 52.12  ? 393 ILE A HG13 1 
ATOM   5954 H HG21 . ILE A 1 393 ? 115.770 96.782  100.296 1.00 52.12  ? 393 ILE A HG21 1 
ATOM   5955 H HG22 . ILE A 1 393 ? 115.376 95.272  100.038 1.00 52.12  ? 393 ILE A HG22 1 
ATOM   5956 H HG23 . ILE A 1 393 ? 116.888 95.654  100.327 1.00 52.12  ? 393 ILE A HG23 1 
ATOM   5957 H HD11 . ILE A 1 393 ? 118.104 98.949  98.580  1.00 52.12  ? 393 ILE A HD11 1 
ATOM   5958 H HD12 . ILE A 1 393 ? 116.559 98.862  98.218  1.00 52.12  ? 393 ILE A HD12 1 
ATOM   5959 H HD13 . ILE A 1 393 ? 117.070 98.416  99.653  1.00 52.12  ? 393 ILE A HD13 1 
ATOM   5960 N N    . LEU A 1 394 ? 117.547 93.297  99.392  1.00 49.02  ? 394 LEU A N    1 
ATOM   5961 C CA   . LEU A 1 394 ? 118.682 92.767  100.142 1.00 49.02  ? 394 LEU A CA   1 
ATOM   5962 C C    . LEU A 1 394 ? 119.570 91.875  99.286  1.00 49.02  ? 394 LEU A C    1 
ATOM   5963 O O    . LEU A 1 394 ? 120.736 91.654  99.632  1.00 49.02  ? 394 LEU A O    1 
ATOM   5964 C CB   . LEU A 1 394 ? 118.182 91.995  101.362 1.00 49.02  ? 394 LEU A CB   1 
ATOM   5965 C CG   . LEU A 1 394 ? 119.259 91.464  102.306 1.00 49.02  ? 394 LEU A CG   1 
ATOM   5966 C CD1  . LEU A 1 394 ? 120.086 92.607  102.861 1.00 49.02  ? 394 LEU A CD1  1 
ATOM   5967 C CD2  . LEU A 1 394 ? 118.635 90.664  103.432 1.00 49.02  ? 394 LEU A CD2  1 
ATOM   5968 H H    . LEU A 1 394 ? 116.778 93.075  99.705  1.00 49.02  ? 394 LEU A H    1 
ATOM   5969 H HA   . LEU A 1 394 ? 119.220 93.510  100.455 1.00 49.02  ? 394 LEU A HA   1 
ATOM   5970 H HB2  . LEU A 1 394 ? 117.610 92.582  101.881 1.00 49.02  ? 394 LEU A HB2  1 
ATOM   5971 H HB3  . LEU A 1 394 ? 117.667 91.233  101.053 1.00 49.02  ? 394 LEU A HB3  1 
ATOM   5972 H HG   . LEU A 1 394 ? 119.852 90.874  101.815 1.00 49.02  ? 394 LEU A HG   1 
ATOM   5973 H HD11 . LEU A 1 394 ? 120.661 92.266  103.564 1.00 49.02  ? 394 LEU A HD11 1 
ATOM   5974 H HD12 . LEU A 1 394 ? 120.626 92.983  102.148 1.00 49.02  ? 394 LEU A HD12 1 
ATOM   5975 H HD13 . LEU A 1 394 ? 119.491 93.283  103.220 1.00 49.02  ? 394 LEU A HD13 1 
ATOM   5976 H HD21 . LEU A 1 394 ? 119.338 90.344  104.018 1.00 49.02  ? 394 LEU A HD21 1 
ATOM   5977 H HD22 . LEU A 1 394 ? 118.028 91.238  103.927 1.00 49.02  ? 394 LEU A HD22 1 
ATOM   5978 H HD23 . LEU A 1 394 ? 118.149 89.913  103.056 1.00 49.02  ? 394 LEU A HD23 1 
ATOM   5979 N N    . VAL A 1 395 ? 119.044 91.340  98.182  1.00 51.12  ? 395 VAL A N    1 
ATOM   5980 C CA   . VAL A 1 395 ? 119.799 90.403  97.356  1.00 51.12  ? 395 VAL A CA   1 
ATOM   5981 C C    . VAL A 1 395 ? 120.248 90.996  96.027  1.00 51.12  ? 395 VAL A C    1 
ATOM   5982 O O    . VAL A 1 395 ? 121.061 90.367  95.331  1.00 51.12  ? 395 VAL A O    1 
ATOM   5983 C CB   . VAL A 1 395 ? 118.979 89.122  97.093  1.00 51.12  ? 395 VAL A CB   1 
ATOM   5984 C CG1  . VAL A 1 395 ? 117.874 89.399  96.092  1.00 51.12  ? 395 VAL A CG1  1 
ATOM   5985 C CG2  . VAL A 1 395 ? 119.882 87.997  96.613  1.00 51.12  ? 395 VAL A CG2  1 
ATOM   5986 H H    . VAL A 1 395 ? 118.253 91.507  97.889  1.00 51.12  ? 395 VAL A H    1 
ATOM   5987 H HA   . VAL A 1 395 ? 120.598 90.139  97.837  1.00 51.12  ? 395 VAL A HA   1 
ATOM   5988 H HB   . VAL A 1 395 ? 118.565 88.839  97.923  1.00 51.12  ? 395 VAL A HB   1 
ATOM   5989 H HG11 . VAL A 1 395 ? 117.204 88.700  96.161  1.00 51.12  ? 395 VAL A HG11 1 
ATOM   5990 H HG12 . VAL A 1 395 ? 117.475 90.260  96.291  1.00 51.12  ? 395 VAL A HG12 1 
ATOM   5991 H HG13 . VAL A 1 395 ? 118.249 89.408  95.197  1.00 51.12  ? 395 VAL A HG13 1 
ATOM   5992 H HG21 . VAL A 1 395 ? 119.390 87.162  96.655  1.00 51.12  ? 395 VAL A HG21 1 
ATOM   5993 H HG22 . VAL A 1 395 ? 120.155 88.173  95.700  1.00 51.12  ? 395 VAL A HG22 1 
ATOM   5994 H HG23 . VAL A 1 395 ? 120.660 87.948  97.190  1.00 51.12  ? 395 VAL A HG23 1 
ATOM   5995 N N    . THR A 1 396 ? 119.757 92.175  95.650  1.00 53.82  ? 396 THR A N    1 
ATOM   5996 C CA   . THR A 1 396 ? 120.030 92.717  94.323  1.00 53.82  ? 396 THR A CA   1 
ATOM   5997 C C    . THR A 1 396 ? 121.109 93.790  94.299  1.00 53.82  ? 396 THR A C    1 
ATOM   5998 O O    . THR A 1 396 ? 121.728 93.994  93.251  1.00 53.82  ? 396 THR A O    1 
ATOM   5999 C CB   . THR A 1 396 ? 118.752 93.303  93.712  1.00 53.82  ? 396 THR A CB   1 
ATOM   6000 O OG1  . THR A 1 396 ? 118.162 94.235  94.624  1.00 53.82  ? 396 THR A OG1  1 
ATOM   6001 C CG2  . THR A 1 396 ? 117.757 92.202  93.393  1.00 53.82  ? 396 THR A CG2  1 
ATOM   6002 H H    . THR A 1 396 ? 119.265 92.679  96.143  1.00 53.82  ? 396 THR A H    1 
ATOM   6003 H HA   . THR A 1 396 ? 120.324 91.995  93.747  1.00 53.82  ? 396 THR A HA   1 
ATOM   6004 H HB   . THR A 1 396 ? 118.975 93.760  92.885  1.00 53.82  ? 396 THR A HB   1 
ATOM   6005 H HG1  . THR A 1 396 ? 117.901 93.836  95.316  1.00 53.82  ? 396 THR A HG1  1 
ATOM   6006 H HG21 . THR A 1 396 ? 116.930 92.588  93.066  1.00 53.82  ? 396 THR A HG21 1 
ATOM   6007 H HG22 . THR A 1 396 ? 118.122 91.614  92.713  1.00 53.82  ? 396 THR A HG22 1 
ATOM   6008 H HG23 . THR A 1 396 ? 117.570 91.684  94.191  1.00 53.82  ? 396 THR A HG23 1 
ATOM   6009 N N    . ILE A 1 397 ? 121.352 94.487  95.409  1.00 55.76  ? 397 ILE A N    1 
ATOM   6010 C CA   . ILE A 1 397 ? 122.223 95.662  95.368  1.00 55.76  ? 397 ILE A CA   1 
ATOM   6011 C C    . ILE A 1 397 ? 123.624 95.276  94.910  1.00 55.76  ? 397 ILE A C    1 
ATOM   6012 O O    . ILE A 1 397 ? 124.082 95.687  93.838  1.00 55.76  ? 397 ILE A O    1 
ATOM   6013 C CB   . ILE A 1 397 ? 122.262 96.355  96.740  1.00 55.76  ? 397 ILE A CB   1 
ATOM   6014 C CG1  . ILE A 1 397 ? 120.867 96.828  97.140  1.00 55.76  ? 397 ILE A CG1  1 
ATOM   6015 C CG2  . ILE A 1 397 ? 123.227 97.523  96.707  1.00 55.76  ? 397 ILE A CG2  1 
ATOM   6016 C CD1  . ILE A 1 397 ? 120.229 97.750  96.135  1.00 55.76  ? 397 ILE A CD1  1 
ATOM   6017 H H    . ILE A 1 397 ? 121.032 94.305  96.186  1.00 55.76  ? 397 ILE A H    1 
ATOM   6018 H HA   . ILE A 1 397 ? 121.877 96.288  94.715  1.00 55.76  ? 397 ILE A HA   1 
ATOM   6019 H HB   . ILE A 1 397 ? 122.573 95.716  97.400  1.00 55.76  ? 397 ILE A HB   1 
ATOM   6020 H HG12 . ILE A 1 397 ? 120.291 96.055  97.241  1.00 55.76  ? 397 ILE A HG12 1 
ATOM   6021 H HG13 . ILE A 1 397 ? 120.928 97.304  97.982  1.00 55.76  ? 397 ILE A HG13 1 
ATOM   6022 H HG21 . ILE A 1 397 ? 123.007 98.135  97.426  1.00 55.76  ? 397 ILE A HG21 1 
ATOM   6023 H HG22 . ILE A 1 397 ? 124.131 97.191  96.819  1.00 55.76  ? 397 ILE A HG22 1 
ATOM   6024 H HG23 . ILE A 1 397 ? 123.142 97.973  95.852  1.00 55.76  ? 397 ILE A HG23 1 
ATOM   6025 H HD11 . ILE A 1 397 ? 119.395 98.073  96.501  1.00 55.76  ? 397 ILE A HD11 1 
ATOM   6026 H HD12 . ILE A 1 397 ? 120.825 98.494  95.959  1.00 55.76  ? 397 ILE A HD12 1 
ATOM   6027 H HD13 . ILE A 1 397 ? 120.055 97.262  95.316  1.00 55.76  ? 397 ILE A HD13 1 
ATOM   6028 N N    . ASP A 1 398 ? 124.325 94.482  95.719  1.00 58.31  ? 398 ASP A N    1 
ATOM   6029 C CA   . ASP A 1 398 ? 125.717 94.174  95.413  1.00 58.31  ? 398 ASP A CA   1 
ATOM   6030 C C    . ASP A 1 398 ? 125.846 93.355  94.138  1.00 58.31  ? 398 ASP A C    1 
ATOM   6031 O O    . ASP A 1 398 ? 126.896 93.387  93.486  1.00 58.31  ? 398 ASP A O    1 
ATOM   6032 C CB   . ASP A 1 398 ? 126.356 93.442  96.590  1.00 58.31  ? 398 ASP A CB   1 
ATOM   6033 C CG   . ASP A 1 398 ? 126.351 94.272  97.856  1.00 58.31  ? 398 ASP A CG   1 
ATOM   6034 O OD1  . ASP A 1 398 ? 125.688 95.330  97.866  1.00 58.31  ? 398 ASP A OD1  1 
ATOM   6035 O OD2  . ASP A 1 398 ? 127.012 93.874  98.838  1.00 58.31  ? 398 ASP A OD2  1 
ATOM   6036 H H    . ASP A 1 398 ? 124.023 94.112  96.434  1.00 58.31  ? 398 ASP A H    1 
ATOM   6037 H HA   . ASP A 1 398 ? 126.201 95.005  95.283  1.00 58.31  ? 398 ASP A HA   1 
ATOM   6038 H HB2  . ASP A 1 398 ? 125.857 92.628  96.763  1.00 58.31  ? 398 ASP A HB2  1 
ATOM   6039 H HB3  . ASP A 1 398 ? 127.276 93.227  96.371  1.00 58.31  ? 398 ASP A HB3  1 
ATOM   6040 N N    . ARG A 1 399 ? 124.801 92.614  93.770  1.00 59.03  ? 399 ARG A N    1 
ATOM   6041 C CA   . ARG A 1 399 ? 124.862 91.802  92.560  1.00 59.03  ? 399 ARG A CA   1 
ATOM   6042 C C    . ARG A 1 399 ? 124.713 92.653  91.303  1.00 59.03  ? 399 ARG A C    1 
ATOM   6043 O O    . ARG A 1 399 ? 125.331 92.356  90.274  1.00 59.03  ? 399 ARG A O    1 
ATOM   6044 C CB   . ARG A 1 399 ? 123.785 90.721  92.607  1.00 59.03  ? 399 ARG A CB   1 
ATOM   6045 C CG   . ARG A 1 399 ? 123.922 89.762  93.780  1.00 59.03  ? 399 ARG A CG   1 
ATOM   6046 C CD   . ARG A 1 399 ? 125.195 88.936  93.697  1.00 59.03  ? 399 ARG A CD   1 
ATOM   6047 N NE   . ARG A 1 399 ? 125.285 88.203  92.441  1.00 59.03  ? 399 ARG A NE   1 
ATOM   6048 C CZ   . ARG A 1 399 ? 124.681 87.048  92.201  1.00 59.03  ? 399 ARG A CZ   1 
ATOM   6049 N NH1  . ARG A 1 399 ? 123.930 86.455  93.116  1.00 59.03  ? 399 ARG A NH1  1 
ATOM   6050 N NH2  . ARG A 1 399 ? 124.829 86.473  91.011  1.00 59.03  ? 399 ARG A NH2  1 
ATOM   6051 H H    . ARG A 1 399 ? 124.055 92.567  94.197  1.00 59.03  ? 399 ARG A H    1 
ATOM   6052 H HA   . ARG A 1 399 ? 125.728 91.366  92.518  1.00 59.03  ? 399 ARG A HA   1 
ATOM   6053 H HB2  . ARG A 1 399 ? 122.918 91.150  92.680  1.00 59.03  ? 399 ARG A HB2  1 
ATOM   6054 H HB3  . ARG A 1 399 ? 123.824 90.203  91.788  1.00 59.03  ? 399 ARG A HB3  1 
ATOM   6055 H HG2  . ARG A 1 399 ? 123.945 90.270  94.605  1.00 59.03  ? 399 ARG A HG2  1 
ATOM   6056 H HG3  . ARG A 1 399 ? 123.166 89.154  93.782  1.00 59.03  ? 399 ARG A HG3  1 
ATOM   6057 H HD2  . ARG A 1 399 ? 125.964 89.524  93.762  1.00 59.03  ? 399 ARG A HD2  1 
ATOM   6058 H HD3  . ARG A 1 399 ? 125.206 88.296  94.425  1.00 59.03  ? 399 ARG A HD3  1 
ATOM   6059 H HE   . ARG A 1 399 ? 125.699 88.580  91.788  1.00 59.03  ? 399 ARG A HE   1 
ATOM   6060 H HH11 . ARG A 1 399 ? 123.825 86.816  93.890  1.00 59.03  ? 399 ARG A HH11 1 
ATOM   6061 H HH12 . ARG A 1 399 ? 123.547 85.706  92.937  1.00 59.03  ? 399 ARG A HH12 1 
ATOM   6062 H HH21 . ARG A 1 399 ? 125.314 86.849  90.408  1.00 59.03  ? 399 ARG A HH21 1 
ATOM   6063 H HH22 . ARG A 1 399 ? 124.441 85.724  90.844  1.00 59.03  ? 399 ARG A HH22 1 
ATOM   6064 N N    . VAL A 1 400 ? 123.895 93.704  91.356  1.00 58.67  ? 400 VAL A N    1 
ATOM   6065 C CA   . VAL A 1 400 ? 123.571 94.500  90.178  1.00 58.67  ? 400 VAL A CA   1 
ATOM   6066 C C    . VAL A 1 400 ? 123.953 95.966  90.326  1.00 58.67  ? 400 VAL A C    1 
ATOM   6067 O O    . VAL A 1 400 ? 123.876 96.711  89.345  1.00 58.67  ? 400 VAL A O    1 
ATOM   6068 C CB   . VAL A 1 400 ? 122.074 94.375  89.825  1.00 58.67  ? 400 VAL A CB   1 
ATOM   6069 C CG1  . VAL A 1 400 ? 121.751 95.126  88.534  1.00 58.67  ? 400 VAL A CG1  1 
ATOM   6070 C CG2  . VAL A 1 400 ? 121.668 92.906  89.712  1.00 58.67  ? 400 VAL A CG2  1 
ATOM   6071 H H    . VAL A 1 400 ? 123.506 93.975  92.074  1.00 58.67  ? 400 VAL A H    1 
ATOM   6072 H HA   . VAL A 1 400 ? 124.072 94.151  89.424  1.00 58.67  ? 400 VAL A HA   1 
ATOM   6073 H HB   . VAL A 1 400 ? 121.549 94.769  90.538  1.00 58.67  ? 400 VAL A HB   1 
ATOM   6074 H HG11 . VAL A 1 400 ? 121.033 94.667  88.071  1.00 58.67  ? 400 VAL A HG11 1 
ATOM   6075 H HG12 . VAL A 1 400 ? 121.469 96.027  88.751  1.00 58.67  ? 400 VAL A HG12 1 
ATOM   6076 H HG13 . VAL A 1 400 ? 122.541 95.148  87.972  1.00 58.67  ? 400 VAL A HG13 1 
ATOM   6077 H HG21 . VAL A 1 400 ? 120.763 92.852  89.367  1.00 58.67  ? 400 VAL A HG21 1 
ATOM   6078 H HG22 . VAL A 1 400 ? 122.278 92.455  89.106  1.00 58.67  ? 400 VAL A HG22 1 
ATOM   6079 H HG23 . VAL A 1 400 ? 121.708 92.494  90.589  1.00 58.67  ? 400 VAL A HG23 1 
ATOM   6080 N N    . GLY A 1 401 ? 124.383 96.402  91.504  1.00 58.69  ? 401 GLY A N    1 
ATOM   6081 C CA   . GLY A 1 401 ? 124.646 97.811  91.722  1.00 58.69  ? 401 GLY A CA   1 
ATOM   6082 C C    . GLY A 1 401 ? 123.449 98.521  92.315  1.00 58.69  ? 401 GLY A C    1 
ATOM   6083 O O    . GLY A 1 401 ? 122.422 97.924  92.650  1.00 58.69  ? 401 GLY A O    1 
ATOM   6084 H H    . GLY A 1 401 ? 124.527 95.904  92.191  1.00 58.69  ? 401 GLY A H    1 
ATOM   6085 H HA2  . GLY A 1 401 ? 125.397 97.915  92.329  1.00 58.69  ? 401 GLY A HA2  1 
ATOM   6086 H HA3  . GLY A 1 401 ? 124.873 98.237  90.881  1.00 58.69  ? 401 GLY A HA3  1 
ATOM   6087 N N    . ARG A 1 402 ? 123.590 99.839  92.457  1.00 55.64  ? 402 ARG A N    1 
ATOM   6088 C CA   . ARG A 1 402 ? 122.577 100.647 93.121  1.00 55.64  ? 402 ARG A CA   1 
ATOM   6089 C C    . ARG A 1 402 ? 121.780 101.547 92.190  1.00 55.64  ? 402 ARG A C    1 
ATOM   6090 O O    . ARG A 1 402 ? 120.600 101.778 92.454  1.00 55.64  ? 402 ARG A O    1 
ATOM   6091 C CB   . ARG A 1 402 ? 123.224 101.512 94.210  1.00 55.64  ? 402 ARG A CB   1 
ATOM   6092 C CG   . ARG A 1 402 ? 123.736 100.701 95.391  1.00 55.64  ? 402 ARG A CG   1 
ATOM   6093 C CD   . ARG A 1 402 ? 124.351 101.576 96.464  1.00 55.64  ? 402 ARG A CD   1 
ATOM   6094 N NE   . ARG A 1 402 ? 124.860 100.779 97.575  1.00 55.64  ? 402 ARG A NE   1 
ATOM   6095 C CZ   . ARG A 1 402 ? 126.049 100.194 97.597  1.00 55.64  ? 402 ARG A CZ   1 
ATOM   6096 N NH1  . ARG A 1 402 ? 126.895 100.305 96.587  1.00 55.64  ? 402 ARG A NH1  1 
ATOM   6097 N NH2  . ARG A 1 402 ? 126.398 99.474  98.659  1.00 55.64  ? 402 ARG A NH2  1 
ATOM   6098 H H    . ARG A 1 402 ? 124.266 100.289 92.175  1.00 55.64  ? 402 ARG A H    1 
ATOM   6099 H HA   . ARG A 1 402 ? 121.944 100.054 93.555  1.00 55.64  ? 402 ARG A HA   1 
ATOM   6100 H HB2  . ARG A 1 402 ? 123.978 101.983 93.826  1.00 55.64  ? 402 ARG A HB2  1 
ATOM   6101 H HB3  . ARG A 1 402 ? 122.571 102.149 94.540  1.00 55.64  ? 402 ARG A HB3  1 
ATOM   6102 H HG2  . ARG A 1 402 ? 122.998 100.212 95.787  1.00 55.64  ? 402 ARG A HG2  1 
ATOM   6103 H HG3  . ARG A 1 402 ? 124.416 100.082 95.081  1.00 55.64  ? 402 ARG A HG3  1 
ATOM   6104 H HD2  . ARG A 1 402 ? 125.086 102.081 96.084  1.00 55.64  ? 402 ARG A HD2  1 
ATOM   6105 H HD3  . ARG A 1 402 ? 123.675 102.181 96.809  1.00 55.64  ? 402 ARG A HD3  1 
ATOM   6106 H HE   . ARG A 1 402 ? 124.316 100.599 98.216  1.00 55.64  ? 402 ARG A HE   1 
ATOM   6107 H HH11 . ARG A 1 402 ? 126.685 100.766 95.893  1.00 55.64  ? 402 ARG A HH11 1 
ATOM   6108 H HH12 . ARG A 1 402 ? 127.661 99.915  96.626  1.00 55.64  ? 402 ARG A HH12 1 
ATOM   6109 H HH21 . ARG A 1 402 ? 125.856 99.394  99.322  1.00 55.64  ? 402 ARG A HH21 1 
ATOM   6110 H HH22 . ARG A 1 402 ? 127.167 99.090  98.684  1.00 55.64  ? 402 ARG A HH22 1 
ATOM   6111 N N    . ILE A 1 403 ? 122.375 102.061 91.112  1.00 57.47  ? 403 ILE A N    1 
ATOM   6112 C CA   . ILE A 1 403 ? 121.654 103.016 90.272  1.00 57.47  ? 403 ILE A CA   1 
ATOM   6113 C C    . ILE A 1 403 ? 120.490 102.340 89.554  1.00 57.47  ? 403 ILE A C    1 
ATOM   6114 O O    . ILE A 1 403 ? 119.372 102.870 89.521  1.00 57.47  ? 403 ILE A O    1 
ATOM   6115 C CB   . ILE A 1 403 ? 122.610 103.703 89.279  1.00 57.47  ? 403 ILE A CB   1 
ATOM   6116 C CG1  . ILE A 1 403 ? 123.456 102.681 88.513  1.00 57.47  ? 403 ILE A CG1  1 
ATOM   6117 C CG2  . ILE A 1 403 ? 123.504 104.677 90.016  1.00 57.47  ? 403 ILE A CG2  1 
ATOM   6118 C CD1  . ILE A 1 403 ? 124.213 103.274 87.339  1.00 57.47  ? 403 ILE A CD1  1 
ATOM   6119 H H    . ILE A 1 403 ? 123.173 101.877 90.853  1.00 57.47  ? 403 ILE A H    1 
ATOM   6120 H HA   . ILE A 1 403 ? 121.279 103.707 90.842  1.00 57.47  ? 403 ILE A HA   1 
ATOM   6121 H HB   . ILE A 1 403 ? 122.078 104.200 88.637  1.00 57.47  ? 403 ILE A HB   1 
ATOM   6122 H HG12 . ILE A 1 403 ? 124.115 102.306 89.117  1.00 57.47  ? 403 ILE A HG12 1 
ATOM   6123 H HG13 . ILE A 1 403 ? 122.888 101.977 88.168  1.00 57.47  ? 403 ILE A HG13 1 
ATOM   6124 H HG21 . ILE A 1 403 ? 124.091 105.114 89.381  1.00 57.47  ? 403 ILE A HG21 1 
ATOM   6125 H HG22 . ILE A 1 403 ? 122.950 105.336 90.462  1.00 57.47  ? 403 ILE A HG22 1 
ATOM   6126 H HG23 . ILE A 1 403 ? 124.028 104.187 90.670  1.00 57.47  ? 403 ILE A HG23 1 
ATOM   6127 H HD11 . ILE A 1 403 ? 124.687 102.566 86.877  1.00 57.47  ? 403 ILE A HD11 1 
ATOM   6128 H HD12 . ILE A 1 403 ? 123.579 103.696 86.737  1.00 57.47  ? 403 ILE A HD12 1 
ATOM   6129 H HD13 . ILE A 1 403 ? 124.844 103.932 87.669  1.00 57.47  ? 403 ILE A HD13 1 
ATOM   6130 N N    . TYR A 1 404 ? 120.727 101.158 88.969  1.00 57.66  ? 404 TYR A N    1 
ATOM   6131 C CA   . TYR A 1 404 ? 119.699 100.548 88.125  1.00 57.66  ? 404 TYR A CA   1 
ATOM   6132 C C    . TYR A 1 404 ? 118.441 100.209 88.911  1.00 57.66  ? 404 TYR A C    1 
ATOM   6133 O O    . TYR A 1 404 ? 117.335 100.552 88.455  1.00 57.66  ? 404 TYR A O    1 
ATOM   6134 C CB   . TYR A 1 404 ? 120.274 99.327  87.408  1.00 57.66  ? 404 TYR A CB   1 
ATOM   6135 C CG   . TYR A 1 404 ? 121.462 99.659  86.536  1.00 57.66  ? 404 TYR A CG   1 
ATOM   6136 C CD1  . TYR A 1 404 ? 121.295 100.297 85.315  1.00 57.66  ? 404 TYR A CD1  1 
ATOM   6137 C CD2  . TYR A 1 404 ? 122.750 99.341  86.937  1.00 57.66  ? 404 TYR A CD2  1 
ATOM   6138 C CE1  . TYR A 1 404 ? 122.381 100.607 84.517  1.00 57.66  ? 404 TYR A CE1  1 
ATOM   6139 C CE2  . TYR A 1 404 ? 123.840 99.645  86.148  1.00 57.66  ? 404 TYR A CE2  1 
ATOM   6140 C CZ   . TYR A 1 404 ? 123.651 100.278 84.939  1.00 57.66  ? 404 TYR A CZ   1 
ATOM   6141 O OH   . TYR A 1 404 ? 124.738 100.582 84.151  1.00 57.66  ? 404 TYR A OH   1 
ATOM   6142 H H    . TYR A 1 404 ? 121.453 100.702 89.042  1.00 57.66  ? 404 TYR A H    1 
ATOM   6143 H HA   . TYR A 1 404 ? 119.444 101.186 87.440  1.00 57.66  ? 404 TYR A HA   1 
ATOM   6144 H HB2  . TYR A 1 404 ? 120.560 98.678  88.070  1.00 57.66  ? 404 TYR A HB2  1 
ATOM   6145 H HB3  . TYR A 1 404 ? 119.586 98.940  86.843  1.00 57.66  ? 404 TYR A HB3  1 
ATOM   6146 H HD1  . TYR A 1 404 ? 120.439 100.521 85.028  1.00 57.66  ? 404 TYR A HD1  1 
ATOM   6147 H HD2  . TYR A 1 404 ? 122.882 98.914  87.753  1.00 57.66  ? 404 TYR A HD2  1 
ATOM   6148 H HE1  . TYR A 1 404 ? 122.256 101.034 83.701  1.00 57.66  ? 404 TYR A HE1  1 
ATOM   6149 H HE2  . TYR A 1 404 ? 124.698 99.425  86.430  1.00 57.66  ? 404 TYR A HE2  1 
ATOM   6150 H HH   . TYR A 1 404 ? 124.485 100.925 83.427  1.00 57.66  ? 404 TYR A HH   1 
ATOM   6151 N N    . PRO A 1 405 ? 118.512 99.518  90.052  1.00 56.64  ? 405 PRO A N    1 
ATOM   6152 C CA   . PRO A 1 405 ? 117.267 99.215  90.774  1.00 56.64  ? 405 PRO A CA   1 
ATOM   6153 C C    . PRO A 1 405 ? 116.531 100.458 91.229  1.00 56.64  ? 405 PRO A C    1 
ATOM   6154 O O    . PRO A 1 405 ? 115.298 100.516 91.137  1.00 56.64  ? 405 PRO A O    1 
ATOM   6155 C CB   . PRO A 1 405 ? 117.743 98.364  91.958  1.00 56.64  ? 405 PRO A CB   1 
ATOM   6156 C CG   . PRO A 1 405 ? 119.169 98.705  92.127  1.00 56.64  ? 405 PRO A CG   1 
ATOM   6157 C CD   . PRO A 1 405 ? 119.694 99.000  90.759  1.00 56.64  ? 405 PRO A CD   1 
ATOM   6158 H HA   . PRO A 1 405 ? 116.676 98.684  90.217  1.00 56.64  ? 405 PRO A HA   1 
ATOM   6159 H HB2  . PRO A 1 405 ? 117.238 98.597  92.753  1.00 56.64  ? 405 PRO A HB2  1 
ATOM   6160 H HB3  . PRO A 1 405 ? 117.638 97.423  91.748  1.00 56.64  ? 405 PRO A HB3  1 
ATOM   6161 H HG2  . PRO A 1 405 ? 119.252 99.483  92.701  1.00 56.64  ? 405 PRO A HG2  1 
ATOM   6162 H HG3  . PRO A 1 405 ? 119.637 97.948  92.512  1.00 56.64  ? 405 PRO A HG3  1 
ATOM   6163 H HD2  . PRO A 1 405 ? 120.390 99.669  90.815  1.00 56.64  ? 405 PRO A HD2  1 
ATOM   6164 H HD3  . PRO A 1 405 ? 120.012 98.187  90.336  1.00 56.64  ? 405 PRO A HD3  1 
ATOM   6165 N N    . LEU A 1 406 ? 117.258 101.465 91.709  1.00 54.56  ? 406 LEU A N    1 
ATOM   6166 C CA   . LEU A 1 406 ? 116.611 102.707 92.111  1.00 54.56  ? 406 LEU A CA   1 
ATOM   6167 C C    . LEU A 1 406 ? 115.858 103.322 90.941  1.00 54.56  ? 406 LEU A C    1 
ATOM   6168 O O    . LEU A 1 406 ? 114.688 103.702 91.069  1.00 54.56  ? 406 LEU A O    1 
ATOM   6169 C CB   . LEU A 1 406 ? 117.652 103.680 92.664  1.00 54.56  ? 406 LEU A CB   1 
ATOM   6170 C CG   . LEU A 1 406 ? 117.163 105.081 93.025  1.00 54.56  ? 406 LEU A CG   1 
ATOM   6171 C CD1  . LEU A 1 406 ? 117.867 105.567 94.275  1.00 54.56  ? 406 LEU A CD1  1 
ATOM   6172 C CD2  . LEU A 1 406 ? 117.400 106.049 91.884  1.00 54.56  ? 406 LEU A CD2  1 
ATOM   6173 H H    . LEU A 1 406 ? 118.111 101.453 91.816  1.00 54.56  ? 406 LEU A H    1 
ATOM   6174 H HA   . LEU A 1 406 ? 115.972 102.518 92.816  1.00 54.56  ? 406 LEU A HA   1 
ATOM   6175 H HB2  . LEU A 1 406 ? 118.025 103.291 93.471  1.00 54.56  ? 406 LEU A HB2  1 
ATOM   6176 H HB3  . LEU A 1 406 ? 118.355 103.781 92.004  1.00 54.56  ? 406 LEU A HB3  1 
ATOM   6177 H HG   . LEU A 1 406 ? 116.210 105.050 93.203  1.00 54.56  ? 406 LEU A HG   1 
ATOM   6178 H HD11 . LEU A 1 406 ? 117.669 106.508 94.406  1.00 54.56  ? 406 LEU A HD11 1 
ATOM   6179 H HD12 . LEU A 1 406 ? 117.546 105.054 95.032  1.00 54.56  ? 406 LEU A HD12 1 
ATOM   6180 H HD13 . LEU A 1 406 ? 118.823 105.442 94.169  1.00 54.56  ? 406 LEU A HD13 1 
ATOM   6181 H HD21 . LEU A 1 406 ? 117.183 106.943 92.188  1.00 54.56  ? 406 LEU A HD21 1 
ATOM   6182 H HD22 . LEU A 1 406 ? 118.333 106.008 91.621  1.00 54.56  ? 406 LEU A HD22 1 
ATOM   6183 H HD23 . LEU A 1 406 ? 116.833 105.806 91.136  1.00 54.56  ? 406 LEU A HD23 1 
ATOM   6184 N N    . ALA A 1 407 ? 116.512 103.416 89.781  1.00 57.68  ? 407 ALA A N    1 
ATOM   6185 C CA   . ALA A 1 407 ? 115.859 104.017 88.624  1.00 57.68  ? 407 ALA A CA   1 
ATOM   6186 C C    . ALA A 1 407 ? 114.632 103.218 88.204  1.00 57.68  ? 407 ALA A C    1 
ATOM   6187 O O    . ALA A 1 407 ? 113.571 103.792 87.927  1.00 57.68  ? 407 ALA A O    1 
ATOM   6188 C CB   . ALA A 1 407 ? 116.845 104.128 87.464  1.00 57.68  ? 407 ALA A CB   1 
ATOM   6189 H H    . ALA A 1 407 ? 117.316 103.142 89.643  1.00 57.68  ? 407 ALA A H    1 
ATOM   6190 H HA   . ALA A 1 407 ? 115.565 104.911 88.856  1.00 57.68  ? 407 ALA A HA   1 
ATOM   6191 H HB1  . ALA A 1 407 ? 116.397 104.537 86.707  1.00 57.68  ? 407 ALA A HB1  1 
ATOM   6192 H HB2  . ALA A 1 407 ? 117.595 104.677 87.741  1.00 57.68  ? 407 ALA A HB2  1 
ATOM   6193 H HB3  . ALA A 1 407 ? 117.155 103.240 87.225  1.00 57.68  ? 407 ALA A HB3  1 
ATOM   6194 N N    . VAL A 1 408 ? 114.750 101.890 88.161  1.00 58.77  ? 408 VAL A N    1 
ATOM   6195 C CA   . VAL A 1 408 ? 113.647 101.074 87.664  1.00 58.77  ? 408 VAL A CA   1 
ATOM   6196 C C    . VAL A 1 408 ? 112.461 101.129 88.620  1.00 58.77  ? 408 VAL A C    1 
ATOM   6197 O O    . VAL A 1 408 ? 111.305 101.161 88.186  1.00 58.77  ? 408 VAL A O    1 
ATOM   6198 C CB   . VAL A 1 408 ? 114.117 99.630  87.417  1.00 58.77  ? 408 VAL A CB   1 
ATOM   6199 C CG1  . VAL A 1 408 ? 112.937 98.747  87.062  1.00 58.77  ? 408 VAL A CG1  1 
ATOM   6200 C CG2  . VAL A 1 408 ? 115.147 99.602  86.302  1.00 58.77  ? 408 VAL A CG2  1 
ATOM   6201 H H    . VAL A 1 408 ? 115.445 101.449 88.410  1.00 58.77  ? 408 VAL A H    1 
ATOM   6202 H HA   . VAL A 1 408 ? 113.353 101.435 86.813  1.00 58.77  ? 408 VAL A HA   1 
ATOM   6203 H HB   . VAL A 1 408 ? 114.529 99.283  88.223  1.00 58.77  ? 408 VAL A HB   1 
ATOM   6204 H HG11 . VAL A 1 408 ? 113.270 97.918  86.683  1.00 58.77  ? 408 VAL A HG11 1 
ATOM   6205 H HG12 . VAL A 1 408 ? 112.422 98.559  87.862  1.00 58.77  ? 408 VAL A HG12 1 
ATOM   6206 H HG13 . VAL A 1 408 ? 112.387 99.210  86.411  1.00 58.77  ? 408 VAL A HG13 1 
ATOM   6207 H HG21 . VAL A 1 408 ? 115.464 98.693  86.184  1.00 58.77  ? 408 VAL A HG21 1 
ATOM   6208 H HG22 . VAL A 1 408 ? 114.731 99.917  85.484  1.00 58.77  ? 408 VAL A HG22 1 
ATOM   6209 H HG23 . VAL A 1 408 ? 115.887 100.182 86.539  1.00 58.77  ? 408 VAL A HG23 1 
ATOM   6210 N N    . SER A 1 409 ? 112.717 101.142 89.931  1.00 57.53  ? 409 SER A N    1 
ATOM   6211 C CA   . SER A 1 409 ? 111.616 101.255 90.883  1.00 57.53  ? 409 SER A CA   1 
ATOM   6212 C C    . SER A 1 409 ? 110.972 102.635 90.818  1.00 57.53  ? 409 SER A C    1 
ATOM   6213 O O    . SER A 1 409 ? 109.739 102.760 90.875  1.00 57.53  ? 409 SER A O    1 
ATOM   6214 C CB   . SER A 1 409 ? 112.113 100.970 92.297  1.00 57.53  ? 409 SER A CB   1 
ATOM   6215 O OG   . SER A 1 409 ? 112.887 102.050 92.783  1.00 57.53  ? 409 SER A OG   1 
ATOM   6216 H H    . SER A 1 409 ? 113.499 101.091 90.285  1.00 57.53  ? 409 SER A H    1 
ATOM   6217 H HA   . SER A 1 409 ? 110.940 100.596 90.665  1.00 57.53  ? 409 SER A HA   1 
ATOM   6218 H HB2  . SER A 1 409 ? 111.351 100.836 92.881  1.00 57.53  ? 409 SER A HB2  1 
ATOM   6219 H HB3  . SER A 1 409 ? 112.664 100.171 92.281  1.00 57.53  ? 409 SER A HB3  1 
ATOM   6220 H HG   . SER A 1 409 ? 113.147 101.888 93.565  1.00 57.53  ? 409 SER A HG   1 
ATOM   6221 N N    . ASN A 1 410 ? 111.789 103.686 90.706  1.00 59.73  ? 410 ASN A N    1 
ATOM   6222 C CA   . ASN A 1 410 ? 111.240 105.027 90.566  1.00 59.73  ? 410 ASN A CA   1 
ATOM   6223 C C    . ASN A 1 410 ? 110.375 105.136 89.320  1.00 59.73  ? 410 ASN A C    1 
ATOM   6224 O O    . ASN A 1 410 ? 109.382 105.871 89.314  1.00 59.73  ? 410 ASN A O    1 
ATOM   6225 C CB   . ASN A 1 410 ? 112.380 106.045 90.523  1.00 59.73  ? 410 ASN A CB   1 
ATOM   6226 C CG   . ASN A 1 410 ? 111.893 107.476 90.610  1.00 59.73  ? 410 ASN A CG   1 
ATOM   6227 O OD1  . ASN A 1 410 ? 111.634 108.120 89.594  1.00 59.73  ? 410 ASN A OD1  1 
ATOM   6228 N ND2  . ASN A 1 410 ? 111.775 107.987 91.830  1.00 59.73  ? 410 ASN A ND2  1 
ATOM   6229 H H    . ASN A 1 410 ? 112.647 103.647 90.711  1.00 59.73  ? 410 ASN A H    1 
ATOM   6230 H HA   . ASN A 1 410 ? 110.686 105.227 91.337  1.00 59.73  ? 410 ASN A HA   1 
ATOM   6231 H HB2  . ASN A 1 410 ? 112.972 105.885 91.275  1.00 59.73  ? 410 ASN A HB2  1 
ATOM   6232 H HB3  . ASN A 1 410 ? 112.866 105.942 89.691  1.00 59.73  ? 410 ASN A HB3  1 
ATOM   6233 H HD21 . ASN A 1 410 ? 111.503 108.796 91.934  1.00 59.73  ? 410 ASN A HD21 1 
ATOM   6234 H HD22 . ASN A 1 410 ? 111.966 107.507 92.518  1.00 59.73  ? 410 ASN A HD22 1 
ATOM   6235 N N    . LEU A 1 411 ? 110.735 104.415 88.257  1.00 63.02  ? 411 LEU A N    1 
ATOM   6236 C CA   . LEU A 1 411 ? 109.915 104.420 87.050  1.00 63.02  ? 411 LEU A CA   1 
ATOM   6237 C C    . LEU A 1 411 ? 108.631 103.618 87.240  1.00 63.02  ? 411 LEU A C    1 
ATOM   6238 O O    . LEU A 1 411 ? 107.550 104.059 86.828  1.00 63.02  ? 411 LEU A O    1 
ATOM   6239 C CB   . LEU A 1 411 ? 110.716 103.865 85.874  1.00 63.02  ? 411 LEU A CB   1 
ATOM   6240 C CG   . LEU A 1 411 ? 109.998 103.851 84.523  1.00 63.02  ? 411 LEU A CG   1 
ATOM   6241 C CD1  . LEU A 1 411 ? 109.668 105.268 84.079  1.00 63.02  ? 411 LEU A CD1  1 
ATOM   6242 C CD2  . LEU A 1 411 ? 110.841 103.143 83.475  1.00 63.02  ? 411 LEU A CD2  1 
ATOM   6243 H H    . LEU A 1 411 ? 111.438 103.923 88.212  1.00 63.02  ? 411 LEU A H    1 
ATOM   6244 H HA   . LEU A 1 411 ? 109.669 105.335 86.843  1.00 63.02  ? 411 LEU A HA   1 
ATOM   6245 H HB2  . LEU A 1 411 ? 111.517 104.402 85.769  1.00 63.02  ? 411 LEU A HB2  1 
ATOM   6246 H HB3  . LEU A 1 411 ? 110.967 102.950 86.078  1.00 63.02  ? 411 LEU A HB3  1 
ATOM   6247 H HG   . LEU A 1 411 ? 109.165 103.364 84.611  1.00 63.02  ? 411 LEU A HG   1 
ATOM   6248 H HD11 . LEU A 1 411 ? 109.266 105.237 83.197  1.00 63.02  ? 411 LEU A HD11 1 
ATOM   6249 H HD12 . LEU A 1 411 ? 109.046 105.661 84.711  1.00 63.02  ? 411 LEU A HD12 1 
ATOM   6250 H HD13 . LEU A 1 411 ? 110.486 105.788 84.053  1.00 63.02  ? 411 LEU A HD13 1 
ATOM   6251 H HD21 . LEU A 1 411 ? 110.379 103.178 82.623  1.00 63.02  ? 411 LEU A HD21 1 
ATOM   6252 H HD22 . LEU A 1 411 ? 111.699 103.591 83.405  1.00 63.02  ? 411 LEU A HD22 1 
ATOM   6253 H HD23 . LEU A 1 411 ? 110.970 102.220 83.744  1.00 63.02  ? 411 LEU A HD23 1 
ATOM   6254 N N    . VAL A 1 412 ? 108.730 102.434 87.849  1.00 65.83  ? 412 VAL A N    1 
ATOM   6255 C CA   . VAL A 1 412 ? 107.573 101.547 87.924  1.00 65.83  ? 412 VAL A CA   1 
ATOM   6256 C C    . VAL A 1 412 ? 106.517 102.099 88.870  1.00 65.83  ? 412 VAL A C    1 
ATOM   6257 O O    . VAL A 1 412 ? 105.323 101.855 88.677  1.00 65.83  ? 412 VAL A O    1 
ATOM   6258 C CB   . VAL A 1 412 ? 107.999 100.125 88.334  1.00 65.83  ? 412 VAL A CB   1 
ATOM   6259 C CG1  . VAL A 1 412 ? 108.266 100.052 89.823  1.00 65.83  ? 412 VAL A CG1  1 
ATOM   6260 C CG2  . VAL A 1 412 ? 106.933 99.118  87.930  1.00 65.83  ? 412 VAL A CG2  1 
ATOM   6261 H H    . VAL A 1 412 ? 109.442 102.127 88.219  1.00 65.83  ? 412 VAL A H    1 
ATOM   6262 H HA   . VAL A 1 412 ? 107.172 101.491 87.042  1.00 65.83  ? 412 VAL A HA   1 
ATOM   6263 H HB   . VAL A 1 412 ? 108.819 99.896  87.869  1.00 65.83  ? 412 VAL A HB   1 
ATOM   6264 H HG11 . VAL A 1 412 ? 108.769 99.245  90.013  1.00 65.83  ? 412 VAL A HG11 1 
ATOM   6265 H HG12 . VAL A 1 412 ? 108.779 100.829 90.085  1.00 65.83  ? 412 VAL A HG12 1 
ATOM   6266 H HG13 . VAL A 1 412 ? 107.421 100.036 90.299  1.00 65.83  ? 412 VAL A HG13 1 
ATOM   6267 H HG21 . VAL A 1 412 ? 107.259 98.223  88.114  1.00 65.83  ? 412 VAL A HG21 1 
ATOM   6268 H HG22 . VAL A 1 412 ? 106.127 99.288  88.443  1.00 65.83  ? 412 VAL A HG22 1 
ATOM   6269 H HG23 . VAL A 1 412 ? 106.749 99.213  86.982  1.00 65.83  ? 412 VAL A HG23 1 
ATOM   6270 N N    . ALA A 1 413 ? 106.915 102.836 89.908  1.00 64.59  ? 413 ALA A N    1 
ATOM   6271 C CA   . ALA A 1 413 ? 105.908 103.457 90.765  1.00 64.59  ? 413 ALA A CA   1 
ATOM   6272 C C    . ALA A 1 413 ? 105.025 104.410 89.963  1.00 64.59  ? 413 ALA A C    1 
ATOM   6273 O O    . ALA A 1 413 ? 103.788 104.343 90.024  1.00 64.59  ? 413 ALA A O    1 
ATOM   6274 C CB   . ALA A 1 413 ? 106.584 104.192 91.921  1.00 64.59  ? 413 ALA A CB   1 
ATOM   6275 H H    . ALA A 1 413 ? 107.732 102.987 90.131  1.00 64.59  ? 413 ALA A H    1 
ATOM   6276 H HA   . ALA A 1 413 ? 105.341 102.766 91.140  1.00 64.59  ? 413 ALA A HA   1 
ATOM   6277 H HB1  . ALA A 1 413 ? 105.903 104.594 92.482  1.00 64.59  ? 413 ALA A HB1  1 
ATOM   6278 H HB2  . ALA A 1 413 ? 107.105 103.556 92.437  1.00 64.59  ? 413 ALA A HB2  1 
ATOM   6279 H HB3  . ALA A 1 413 ? 107.166 104.880 91.560  1.00 64.59  ? 413 ALA A HB3  1 
ATOM   6280 N N    . GLY A 1 414 ? 105.649 105.302 89.193  1.00 70.38  ? 414 GLY A N    1 
ATOM   6281 C CA   . GLY A 1 414 ? 104.880 106.212 88.362  1.00 70.38  ? 414 GLY A CA   1 
ATOM   6282 C C    . GLY A 1 414 ? 104.081 105.488 87.296  1.00 70.38  ? 414 GLY A C    1 
ATOM   6283 O O    . GLY A 1 414 ? 102.965 105.893 86.960  1.00 70.38  ? 414 GLY A O    1 
ATOM   6284 H H    . GLY A 1 414 ? 106.502 105.396 89.137  1.00 70.38  ? 414 GLY A H    1 
ATOM   6285 H HA2  . GLY A 1 414 ? 104.265 106.716 88.918  1.00 70.38  ? 414 GLY A HA2  1 
ATOM   6286 H HA3  . GLY A 1 414 ? 105.481 106.836 87.925  1.00 70.38  ? 414 GLY A HA3  1 
ATOM   6287 N N    . ALA A 1 415 ? 104.641 104.410 86.745  1.00 74.70  ? 415 ALA A N    1 
ATOM   6288 C CA   . ALA A 1 415 ? 103.898 103.628 85.762  1.00 74.70  ? 415 ALA A CA   1 
ATOM   6289 C C    . ALA A 1 415 ? 102.647 103.021 86.382  1.00 74.70  ? 415 ALA A C    1 
ATOM   6290 O O    . ALA A 1 415 ? 101.588 102.978 85.747  1.00 74.70  ? 415 ALA A O    1 
ATOM   6291 C CB   . ALA A 1 415 ? 104.787 102.533 85.174  1.00 74.70  ? 415 ALA A CB   1 
ATOM   6292 H H    . ALA A 1 415 ? 105.430 104.116 86.921  1.00 74.70  ? 415 ALA A H    1 
ATOM   6293 H HA   . ALA A 1 415 ? 103.620 104.211 85.039  1.00 74.70  ? 415 ALA A HA   1 
ATOM   6294 H HB1  . ALA A 1 415 ? 104.271 102.025 84.527  1.00 74.70  ? 415 ALA A HB1  1 
ATOM   6295 H HB2  . ALA A 1 415 ? 105.550 102.944 84.740  1.00 74.70  ? 415 ALA A HB2  1 
ATOM   6296 H HB3  . ALA A 1 415 ? 105.084 101.950 85.890  1.00 74.70  ? 415 ALA A HB3  1 
ATOM   6297 N N    . ALA A 1 416 ? 102.753 102.534 87.618  1.00 77.74  ? 416 ALA A N    1 
ATOM   6298 C CA   . ALA A 1 416 ? 101.584 101.990 88.298  1.00 77.74  ? 416 ALA A CA   1 
ATOM   6299 C C    . ALA A 1 416 ? 100.552 103.077 88.564  1.00 77.74  ? 416 ALA A C    1 
ATOM   6300 O O    . ALA A 1 416 ? 99.347  102.845 88.413  1.00 77.74  ? 416 ALA A O    1 
ATOM   6301 C CB   . ALA A 1 416 ? 102.002 101.313 89.602  1.00 77.74  ? 416 ALA A CB   1 
ATOM   6302 H H    . ALA A 1 416 ? 103.480 102.507 88.077  1.00 77.74  ? 416 ALA A H    1 
ATOM   6303 H HA   . ALA A 1 416 ? 101.173 101.320 87.730  1.00 77.74  ? 416 ALA A HA   1 
ATOM   6304 H HB1  . ALA A 1 416 ? 101.213 100.957 90.040  1.00 77.74  ? 416 ALA A HB1  1 
ATOM   6305 H HB2  . ALA A 1 416 ? 102.619 100.592 89.397  1.00 77.74  ? 416 ALA A HB2  1 
ATOM   6306 H HB3  . ALA A 1 416 ? 102.434 101.965 90.175  1.00 77.74  ? 416 ALA A HB3  1 
ATOM   6307 N N    . CYS A 1 417 ? 100.998 104.269 88.962  1.00 78.43  ? 417 CYS A N    1 
ATOM   6308 C CA   . CYS A 1 417 ? 100.046 105.364 89.135  1.00 78.43  ? 417 CYS A CA   1 
ATOM   6309 C C    . CYS A 1 417 ? 99.327  105.672 87.825  1.00 78.43  ? 417 CYS A C    1 
ATOM   6310 O O    . CYS A 1 417 ? 98.101  105.851 87.801  1.00 78.43  ? 417 CYS A O    1 
ATOM   6311 C CB   . CYS A 1 417 ? 100.760 106.607 89.663  1.00 78.43  ? 417 CYS A CB   1 
ATOM   6312 S SG   . CYS A 1 417 ? 101.311 106.464 91.373  1.00 78.43  ? 417 CYS A SG   1 
ATOM   6313 H H    . CYS A 1 417 ? 101.818 104.466 89.131  1.00 78.43  ? 417 CYS A H    1 
ATOM   6314 H HA   . CYS A 1 417 ? 99.378  105.103 89.788  1.00 78.43  ? 417 CYS A HA   1 
ATOM   6315 H HB2  . CYS A 1 417 ? 101.541 106.777 89.114  1.00 78.43  ? 417 CYS A HB2  1 
ATOM   6316 H HB3  . CYS A 1 417 ? 100.153 107.362 89.611  1.00 78.43  ? 417 CYS A HB3  1 
ATOM   6317 H HG   . CYS A 1 417 ? 101.817 107.502 91.699  1.00 78.43  ? 417 CYS A HG   1 
ATOM   6318 N N    . LEU A 1 418 ? 100.075 105.720 86.721  1.00 81.85  ? 418 LEU A N    1 
ATOM   6319 C CA   . LEU A 1 418 ? 99.470  105.987 85.419  1.00 81.85  ? 418 LEU A CA   1 
ATOM   6320 C C    . LEU A 1 418 ? 98.468  104.905 85.035  1.00 81.85  ? 418 LEU A C    1 
ATOM   6321 O O    . LEU A 1 418 ? 97.384  105.207 84.524  1.00 81.85  ? 418 LEU A O    1 
ATOM   6322 C CB   . LEU A 1 418 ? 100.560 106.105 84.353  1.00 81.85  ? 418 LEU A CB   1 
ATOM   6323 C CG   . LEU A 1 418 ? 100.087 106.357 82.920  1.00 81.85  ? 418 LEU A CG   1 
ATOM   6324 C CD1  . LEU A 1 418 ? 101.075 107.253 82.195  1.00 81.85  ? 418 LEU A CD1  1 
ATOM   6325 C CD2  . LEU A 1 418 ? 99.896  105.051 82.157  1.00 81.85  ? 418 LEU A CD2  1 
ATOM   6326 H H    . LEU A 1 418 ? 100.928 105.611 86.701  1.00 81.85  ? 418 LEU A H    1 
ATOM   6327 H HA   . LEU A 1 418 ? 98.997  106.834 85.459  1.00 81.85  ? 418 LEU A HA   1 
ATOM   6328 H HB2  . LEU A 1 418 ? 101.145 106.839 84.592  1.00 81.85  ? 418 LEU A HB2  1 
ATOM   6329 H HB3  . LEU A 1 418 ? 101.071 105.281 84.350  1.00 81.85  ? 418 LEU A HB3  1 
ATOM   6330 H HG   . LEU A 1 418 ? 99.232  106.814 82.948  1.00 81.85  ? 418 LEU A HG   1 
ATOM   6331 H HD11 . LEU A 1 418 ? 100.784 107.363 81.277  1.00 81.85  ? 418 LEU A HD11 1 
ATOM   6332 H HD12 . LEU A 1 418 ? 101.103 108.115 82.639  1.00 81.85  ? 418 LEU A HD12 1 
ATOM   6333 H HD13 . LEU A 1 418 ? 101.953 106.839 82.217  1.00 81.85  ? 418 LEU A HD13 1 
ATOM   6334 H HD21 . LEU A 1 418 ? 99.776  105.254 81.216  1.00 81.85  ? 418 LEU A HD21 1 
ATOM   6335 H HD22 . LEU A 1 418 ? 100.681 104.494 82.276  1.00 81.85  ? 418 LEU A HD22 1 
ATOM   6336 H HD23 . LEU A 1 418 ? 99.112  104.593 82.496  1.00 81.85  ? 418 LEU A HD23 1 
ATOM   6337 N N    . ILE A 1 419 ? 98.816  103.635 85.255  1.00 87.98  ? 419 ILE A N    1 
ATOM   6338 C CA   . ILE A 1 419 ? 97.912  102.556 84.870  1.00 87.98  ? 419 ILE A CA   1 
ATOM   6339 C C    . ILE A 1 419 ? 96.666  102.567 85.745  1.00 87.98  ? 419 ILE A C    1 
ATOM   6340 O O    . ILE A 1 419 ? 95.570  102.232 85.279  1.00 87.98  ? 419 ILE A O    1 
ATOM   6341 C CB   . ILE A 1 419 ? 98.638  101.199 84.924  1.00 87.98  ? 419 ILE A CB   1 
ATOM   6342 C CG1  . ILE A 1 419 ? 98.097  100.261 83.846  1.00 87.98  ? 419 ILE A CG1  1 
ATOM   6343 C CG2  . ILE A 1 419 ? 98.475  100.539 86.279  1.00 87.98  ? 419 ILE A CG2  1 
ATOM   6344 C CD1  . ILE A 1 419 ? 98.537  100.617 82.444  1.00 87.98  ? 419 ILE A CD1  1 
ATOM   6345 H H    . ILE A 1 419 ? 99.553  103.377 85.616  1.00 87.98  ? 419 ILE A H    1 
ATOM   6346 H HA   . ILE A 1 419 ? 97.628  102.698 83.953  1.00 87.98  ? 419 ILE A HA   1 
ATOM   6347 H HB   . ILE A 1 419 ? 99.581  101.343 84.757  1.00 87.98  ? 419 ILE A HB   1 
ATOM   6348 H HG12 . ILE A 1 419 ? 98.409  99.363  84.039  1.00 87.98  ? 419 ILE A HG12 1 
ATOM   6349 H HG13 . ILE A 1 419 ? 97.128  100.292 83.866  1.00 87.98  ? 419 ILE A HG13 1 
ATOM   6350 H HG21 . ILE A 1 419 ? 99.100  99.801  86.342  1.00 87.98  ? 419 ILE A HG21 1 
ATOM   6351 H HG22 . ILE A 1 419 ? 98.662  101.184 86.976  1.00 87.98  ? 419 ILE A HG22 1 
ATOM   6352 H HG23 . ILE A 1 419 ? 97.568  100.206 86.361  1.00 87.98  ? 419 ILE A HG23 1 
ATOM   6353 H HD11 . ILE A 1 419 ? 98.261  99.915  81.835  1.00 87.98  ? 419 ILE A HD11 1 
ATOM   6354 H HD12 . ILE A 1 419 ? 98.127  101.457 82.186  1.00 87.98  ? 419 ILE A HD12 1 
ATOM   6355 H HD13 . ILE A 1 419 ? 99.503  100.700 82.435  1.00 87.98  ? 419 ILE A HD13 1 
ATOM   6356 N N    . MET A 1 420 ? 96.803  102.940 87.020  1.00 88.97  ? 420 MET A N    1 
ATOM   6357 C CA   . MET A 1 420 ? 95.630  103.075 87.875  1.00 88.97  ? 420 MET A CA   1 
ATOM   6358 C C    . MET A 1 420 ? 94.739  104.212 87.394  1.00 88.97  ? 420 MET A C    1 
ATOM   6359 O O    . MET A 1 420 ? 93.508  104.119 87.464  1.00 88.97  ? 420 MET A O    1 
ATOM   6360 C CB   . MET A 1 420 ? 96.063  103.304 89.323  1.00 88.97  ? 420 MET A CB   1 
ATOM   6361 C CG   . MET A 1 420 ? 94.908  103.394 90.307  1.00 88.97  ? 420 MET A CG   1 
ATOM   6362 S SD   . MET A 1 420 ? 95.456  103.648 92.006  1.00 88.97  ? 420 MET A SD   1 
ATOM   6363 C CE   . MET A 1 420 ? 93.892  103.593 92.882  1.00 88.97  ? 420 MET A CE   1 
ATOM   6364 H H    . MET A 1 420 ? 97.549  103.121 87.407  1.00 88.97  ? 420 MET A H    1 
ATOM   6365 H HA   . MET A 1 420 ? 95.123  102.249 87.846  1.00 88.97  ? 420 MET A HA   1 
ATOM   6366 H HB2  . MET A 1 420 ? 96.629  102.566 89.599  1.00 88.97  ? 420 MET A HB2  1 
ATOM   6367 H HB3  . MET A 1 420 ? 96.560  104.135 89.371  1.00 88.97  ? 420 MET A HB3  1 
ATOM   6368 H HG2  . MET A 1 420 ? 94.338  104.139 90.063  1.00 88.97  ? 420 MET A HG2  1 
ATOM   6369 H HG3  . MET A 1 420 ? 94.404  102.566 90.275  1.00 88.97  ? 420 MET A HG3  1 
ATOM   6370 H HE1  . MET A 1 420 ? 94.047  103.789 93.819  1.00 88.97  ? 420 MET A HE1  1 
ATOM   6371 H HE2  . MET A 1 420 ? 93.292  104.252 92.501  1.00 88.97  ? 420 MET A HE2  1 
ATOM   6372 H HE3  . MET A 1 420 ? 93.509  102.708 92.790  1.00 88.97  ? 420 MET A HE3  1 
ATOM   6373 N N    . ILE A 1 421 ? 95.345  105.296 86.909  1.00 89.47  ? 421 ILE A N    1 
ATOM   6374 C CA   . ILE A 1 421 ? 94.562  106.394 86.350  1.00 89.47  ? 421 ILE A CA   1 
ATOM   6375 C C    . ILE A 1 421 ? 93.812  105.935 85.103  1.00 89.47  ? 421 ILE A C    1 
ATOM   6376 O O    . ILE A 1 421 ? 92.604  106.161 84.966  1.00 89.47  ? 421 ILE A O    1 
ATOM   6377 C CB   . ILE A 1 421 ? 95.474  107.595 86.043  1.00 89.47  ? 421 ILE A CB   1 
ATOM   6378 H H    . ILE A 1 421 ? 96.196  105.418 86.893  1.00 89.47  ? 421 ILE A H    1 
ATOM   6379 H HA   . ILE A 1 421 ? 93.906  106.680 87.004  1.00 89.47  ? 421 ILE A HA   1 
ATOM   6380 N N    . PHE A 1 422 ? 94.515  105.278 84.179  1.00 93.39  ? 422 PHE A N    1 
ATOM   6381 C CA   . PHE A 1 422 ? 93.913  104.931 82.894  1.00 93.39  ? 422 PHE A CA   1 
ATOM   6382 C C    . PHE A 1 422 ? 92.953  103.754 83.028  1.00 93.39  ? 422 PHE A C    1 
ATOM   6383 O O    . PHE A 1 422 ? 91.772  103.863 82.680  1.00 93.39  ? 422 PHE A O    1 
ATOM   6384 C CB   . PHE A 1 422 ? 95.008  104.617 81.874  1.00 93.39  ? 422 PHE A CB   1 
ATOM   6385 C CG   . PHE A 1 422 ? 94.487  104.090 80.566  1.00 93.39  ? 422 PHE A CG   1 
ATOM   6386 C CD1  . PHE A 1 422 ? 94.059  104.956 79.573  1.00 93.39  ? 422 PHE A CD1  1 
ATOM   6387 C CD2  . PHE A 1 422 ? 94.431  102.727 80.327  1.00 93.39  ? 422 PHE A CD2  1 
ATOM   6388 C CE1  . PHE A 1 422 ? 93.580  104.471 78.368  1.00 93.39  ? 422 PHE A CE1  1 
ATOM   6389 C CE2  . PHE A 1 422 ? 93.954  102.237 79.125  1.00 93.39  ? 422 PHE A CE2  1 
ATOM   6390 C CZ   . PHE A 1 422 ? 93.529  103.111 78.145  1.00 93.39  ? 422 PHE A CZ   1 
ATOM   6391 H H    . PHE A 1 422 ? 95.331  105.024 84.272  1.00 93.39  ? 422 PHE A H    1 
ATOM   6392 H HA   . PHE A 1 422 ? 93.408  105.691 82.567  1.00 93.39  ? 422 PHE A HA   1 
ATOM   6393 H HB2  . PHE A 1 422 ? 95.504  105.430 81.689  1.00 93.39  ? 422 PHE A HB2  1 
ATOM   6394 H HB3  . PHE A 1 422 ? 95.603  103.949 82.249  1.00 93.39  ? 422 PHE A HB3  1 
ATOM   6395 H HD1  . PHE A 1 422 ? 94.091  105.874 79.718  1.00 93.39  ? 422 PHE A HD1  1 
ATOM   6396 H HD2  . PHE A 1 422 ? 94.716  102.133 80.985  1.00 93.39  ? 422 PHE A HD2  1 
ATOM   6397 H HE1  . PHE A 1 422 ? 93.294  105.062 77.709  1.00 93.39  ? 422 PHE A HE1  1 
ATOM   6398 H HE2  . PHE A 1 422 ? 93.921  101.319 78.977  1.00 93.39  ? 422 PHE A HE2  1 
ATOM   6399 H HZ   . PHE A 1 422 ? 93.208  102.783 77.336  1.00 93.39  ? 422 PHE A HZ   1 
ATOM   6400 N N    . ILE A 1 423 ? 93.442  102.618 83.532  1.00 95.31  ? 423 ILE A N    1 
ATOM   6401 C CA   . ILE A 1 423 ? 92.590  101.437 83.630  1.00 95.31  ? 423 ILE A CA   1 
ATOM   6402 C C    . ILE A 1 423 ? 91.485  101.681 84.656  1.00 95.31  ? 423 ILE A C    1 
ATOM   6403 O O    . ILE A 1 423 ? 91.587  102.542 85.539  1.00 95.31  ? 423 ILE A O    1 
ATOM   6404 C CB   . ILE A 1 423 ? 93.429  100.193 83.979  1.00 95.31  ? 423 ILE A CB   1 
ATOM   6405 C CG1  . ILE A 1 423 ? 94.379  99.866  82.816  1.00 95.31  ? 423 ILE A CG1  1 
ATOM   6406 C CG2  . ILE A 1 423 ? 92.529  99.001  84.337  1.00 95.31  ? 423 ILE A CG2  1 
ATOM   6407 C CD1  . ILE A 1 423 ? 95.070  98.506  82.900  1.00 95.31  ? 423 ILE A CD1  1 
ATOM   6408 H H    . ILE A 1 423 ? 94.245  102.510 83.820  1.00 95.31  ? 423 ILE A H    1 
ATOM   6409 H HA   . ILE A 1 423 ? 92.172  101.280 82.769  1.00 95.31  ? 423 ILE A HA   1 
ATOM   6410 H HB   . ILE A 1 423 ? 93.969  100.403 84.755  1.00 95.31  ? 423 ILE A HB   1 
ATOM   6411 H HG12 . ILE A 1 423 ? 93.877  99.889  81.987  1.00 95.31  ? 423 ILE A HG12 1 
ATOM   6412 H HG13 . ILE A 1 423 ? 95.076  100.540 82.791  1.00 95.31  ? 423 ILE A HG13 1 
ATOM   6413 H HG21 . ILE A 1 423 ? 93.060  98.196  84.419  1.00 95.31  ? 423 ILE A HG21 1 
ATOM   6414 H HG22 . ILE A 1 423 ? 92.097  99.175  85.187  1.00 95.31  ? 423 ILE A HG22 1 
ATOM   6415 H HG23 . ILE A 1 423 ? 91.862  98.889  83.643  1.00 95.31  ? 423 ILE A HG23 1 
ATOM   6416 H HD11 . ILE A 1 423 ? 95.897  98.541  82.393  1.00 95.31  ? 423 ILE A HD11 1 
ATOM   6417 H HD12 . ILE A 1 423 ? 95.260  98.299  83.828  1.00 95.31  ? 423 ILE A HD12 1 
ATOM   6418 H HD13 . ILE A 1 423 ? 94.483  97.830  82.528  1.00 95.31  ? 423 ILE A HD13 1 
ATOM   6419 N N    . SER A 1 424 ? 90.408  100.906 84.530  1.00 103.31 ? 424 SER A N    1 
ATOM   6420 C CA   . SER A 1 424 ? 89.229  101.110 85.361  1.00 103.31 ? 424 SER A CA   1 
ATOM   6421 C C    . SER A 1 424 ? 89.596  101.091 86.838  1.00 103.31 ? 424 SER A C    1 
ATOM   6422 O O    . SER A 1 424 ? 90.307  100.196 87.306  1.00 103.31 ? 424 SER A O    1 
ATOM   6423 C CB   . SER A 1 424 ? 88.191  100.027 85.066  1.00 103.31 ? 424 SER A CB   1 
ATOM   6424 O OG   . SER A 1 424 ? 87.088  100.126 85.951  1.00 103.31 ? 424 SER A OG   1 
ATOM   6425 H H    . SER A 1 424 ? 90.332  100.261 83.967  1.00 103.31 ? 424 SER A H    1 
ATOM   6426 H HA   . SER A 1 424 ? 88.835  101.972 85.154  1.00 103.31 ? 424 SER A HA   1 
ATOM   6427 H HB2  . SER A 1 424 ? 87.877  100.129 84.154  1.00 103.31 ? 424 SER A HB2  1 
ATOM   6428 H HB3  . SER A 1 424 ? 88.604  99.156  85.178  1.00 103.31 ? 424 SER A HB3  1 
ATOM   6429 H HG   . SER A 1 424 ? 86.570  99.475  85.839  1.00 103.31 ? 424 SER A HG   1 
ATOM   6430 N N    . GLN A 1 425 ? 89.102  102.086 87.572  1.00 103.86 ? 425 GLN A N    1 
ATOM   6431 C CA   . GLN A 1 425 ? 89.308  102.187 89.010  1.00 103.86 ? 425 GLN A CA   1 
ATOM   6432 C C    . GLN A 1 425 ? 88.136  101.636 89.808  1.00 103.86 ? 425 GLN A C    1 
ATOM   6433 O O    . GLN A 1 425 ? 88.141  101.733 91.039  1.00 103.86 ? 425 GLN A O    1 
ATOM   6434 C CB   . GLN A 1 425 ? 89.558  103.647 89.404  1.00 103.86 ? 425 GLN A CB   1 
ATOM   6435 H H    . GLN A 1 425 ? 88.630  102.728 87.249  1.00 103.86 ? 425 GLN A H    1 
ATOM   6436 H HA   . GLN A 1 425 ? 90.097  101.676 89.250  1.00 103.86 ? 425 GLN A HA   1 
ATOM   6437 N N    . ASP A 1 426 ? 87.137  101.064 89.142  1.00 105.78 ? 426 ASP A N    1 
ATOM   6438 C CA   . ASP A 1 426 ? 85.985  100.518 89.840  1.00 105.78 ? 426 ASP A CA   1 
ATOM   6439 C C    . ASP A 1 426 ? 86.406  99.355  90.730  1.00 105.78 ? 426 ASP A C    1 
ATOM   6440 O O    . ASP A 1 426 ? 87.401  98.673  90.472  1.00 105.78 ? 426 ASP A O    1 
ATOM   6441 C CB   . ASP A 1 426 ? 84.924  100.059 88.841  1.00 105.78 ? 426 ASP A CB   1 
ATOM   6442 C CG   . ASP A 1 426 ? 84.337  101.208 88.047  1.00 105.78 ? 426 ASP A CG   1 
ATOM   6443 O OD1  . ASP A 1 426 ? 84.773  102.360 88.253  1.00 105.78 ? 426 ASP A OD1  1 
ATOM   6444 O OD2  . ASP A 1 426 ? 83.438  100.959 87.216  1.00 105.78 ? 426 ASP A OD2  1 
ATOM   6445 H H    . ASP A 1 426 ? 87.105  100.977 88.287  1.00 105.78 ? 426 ASP A H    1 
ATOM   6446 H HA   . ASP A 1 426 ? 85.595  101.207 90.402  1.00 105.78 ? 426 ASP A HA   1 
ATOM   6447 H HB2  . ASP A 1 426 ? 85.330  99.442  88.214  1.00 105.78 ? 426 ASP A HB2  1 
ATOM   6448 H HB3  . ASP A 1 426 ? 84.202  99.623  89.320  1.00 105.78 ? 426 ASP A HB3  1 
ATOM   6449 N N    . LEU A 1 427 ? 85.634  99.138  91.792  1.00 105.14 ? 427 LEU A N    1 
ATOM   6450 C CA   . LEU A 1 427 ? 85.977  98.133  92.790  1.00 105.14 ? 427 LEU A CA   1 
ATOM   6451 C C    . LEU A 1 427 ? 86.230  96.782  92.138  1.00 105.14 ? 427 LEU A C    1 
ATOM   6452 O O    . LEU A 1 427 ? 85.311  96.157  91.600  1.00 105.14 ? 427 LEU A O    1 
ATOM   6453 C CB   . LEU A 1 427 ? 84.850  98.023  93.819  1.00 105.14 ? 427 LEU A CB   1 
ATOM   6454 H H    . LEU A 1 427 ? 84.904  99.562  91.956  1.00 105.14 ? 427 LEU A H    1 
ATOM   6455 H HA   . LEU A 1 427 ? 86.786  98.404  93.252  1.00 105.14 ? 427 LEU A HA   1 
ATOM   6456 N N    . HIS A 1 428 ? 87.482  96.335  92.193  1.00 101.39 ? 428 HIS A N    1 
ATOM   6457 C CA   . HIS A 1 428 ? 87.871  95.039  91.655  1.00 101.39 ? 428 HIS A CA   1 
ATOM   6458 C C    . HIS A 1 428 ? 89.100  94.555  92.408  1.00 101.39 ? 428 HIS A C    1 
ATOM   6459 O O    . HIS A 1 428 ? 89.817  95.340  93.034  1.00 101.39 ? 428 HIS A O    1 
ATOM   6460 C CB   . HIS A 1 428 ? 88.149  95.111  90.149  1.00 101.39 ? 428 HIS A CB   1 
ATOM   6461 C CG   . HIS A 1 428 ? 86.938  95.423  89.326  1.00 101.39 ? 428 HIS A CG   1 
ATOM   6462 N ND1  . HIS A 1 428 ? 86.620  96.703  88.925  1.00 101.39 ? 428 HIS A ND1  1 
ATOM   6463 C CD2  . HIS A 1 428 ? 85.961  94.622  88.840  1.00 101.39 ? 428 HIS A CD2  1 
ATOM   6464 C CE1  . HIS A 1 428 ? 85.502  96.675  88.221  1.00 101.39 ? 428 HIS A CE1  1 
ATOM   6465 N NE2  . HIS A 1 428 ? 85.082  95.425  88.155  1.00 101.39 ? 428 HIS A NE2  1 
ATOM   6466 H H    . HIS A 1 428 ? 88.135  96.774  92.542  1.00 101.39 ? 428 HIS A H    1 
ATOM   6467 H HA   . HIS A 1 428 ? 87.153  94.403  91.801  1.00 101.39 ? 428 HIS A HA   1 
ATOM   6468 H HB2  . HIS A 1 428 ? 88.805  95.807  89.985  1.00 101.39 ? 428 HIS A HB2  1 
ATOM   6469 H HB3  . HIS A 1 428 ? 88.496  94.255  89.853  1.00 101.39 ? 428 HIS A HB3  1 
ATOM   6470 H HD2  . HIS A 1 428 ? 85.898  93.701  88.947  1.00 101.39 ? 428 HIS A HD2  1 
ATOM   6471 H HE1  . HIS A 1 428 ? 85.082  97.411  87.837  1.00 101.39 ? 428 HIS A HE1  1 
ATOM   6472 H HE2  . HIS A 1 428 ? 84.372  95.157  87.749  1.00 101.39 ? 428 HIS A HE2  1 
ATOM   6473 N N    . TRP A 1 429 ? 89.333  93.242  92.341  1.00 94.64  ? 429 TRP A N    1 
ATOM   6474 C CA   . TRP A 1 429 ? 90.461  92.657  93.059  1.00 94.64  ? 429 TRP A CA   1 
ATOM   6475 C C    . TRP A 1 429 ? 91.795  93.191  92.549  1.00 94.64  ? 429 TRP A C    1 
ATOM   6476 O O    . TRP A 1 429 ? 92.777  93.222  93.298  1.00 94.64  ? 429 TRP A O    1 
ATOM   6477 C CB   . TRP A 1 429 ? 90.422  91.132  92.943  1.00 94.64  ? 429 TRP A CB   1 
ATOM   6478 C CG   . TRP A 1 429 ? 90.789  90.612  91.586  1.00 94.64  ? 429 TRP A CG   1 
ATOM   6479 C CD1  . TRP A 1 429 ? 89.955  90.436  90.521  1.00 94.64  ? 429 TRP A CD1  1 
ATOM   6480 C CD2  . TRP A 1 429 ? 92.088  90.194  91.151  1.00 94.64  ? 429 TRP A CD2  1 
ATOM   6481 N NE1  . TRP A 1 429 ? 90.655  89.937  89.449  1.00 94.64  ? 429 TRP A NE1  1 
ATOM   6482 C CE2  . TRP A 1 429 ? 91.967  89.779  89.810  1.00 94.64  ? 429 TRP A CE2  1 
ATOM   6483 C CE3  . TRP A 1 429 ? 93.343  90.130  91.765  1.00 94.64  ? 429 TRP A CE3  1 
ATOM   6484 C CZ2  . TRP A 1 429 ? 93.051  89.309  89.073  1.00 94.64  ? 429 TRP A CZ2  1 
ATOM   6485 C CZ3  . TRP A 1 429 ? 94.418  89.663  91.032  1.00 94.64  ? 429 TRP A CZ3  1 
ATOM   6486 C CH2  . TRP A 1 429 ? 94.266  89.258  89.700  1.00 94.64  ? 429 TRP A CH2  1 
ATOM   6487 H H    . TRP A 1 429 ? 88.860  92.679  91.894  1.00 94.64  ? 429 TRP A H    1 
ATOM   6488 H HA   . TRP A 1 429 ? 90.388  92.886  93.998  1.00 94.64  ? 429 TRP A HA   1 
ATOM   6489 H HB2  . TRP A 1 429 ? 91.045  90.753  93.583  1.00 94.64  ? 429 TRP A HB2  1 
ATOM   6490 H HB3  . TRP A 1 429 ? 89.523  90.827  93.142  1.00 94.64  ? 429 TRP A HB3  1 
ATOM   6491 H HD1  . TRP A 1 429 ? 89.045  90.627  90.519  1.00 94.64  ? 429 TRP A HD1  1 
ATOM   6492 H HE1  . TRP A 1 429 ? 90.324  89.754  88.676  1.00 94.64  ? 429 TRP A HE1  1 
ATOM   6493 H HE3  . TRP A 1 429 ? 93.452  90.397  92.650  1.00 94.64  ? 429 TRP A HE3  1 
ATOM   6494 H HZ2  . TRP A 1 429 ? 92.954  89.039  88.188  1.00 94.64  ? 429 TRP A HZ2  1 
ATOM   6495 H HZ3  . TRP A 1 429 ? 95.257  89.617  91.430  1.00 94.64  ? 429 TRP A HZ3  1 
ATOM   6496 H HH2  . TRP A 1 429 ? 95.007  88.949  89.232  1.00 94.64  ? 429 TRP A HH2  1 
ATOM   6497 N N    . LEU A 1 430 ? 91.853  93.612  91.284  1.00 93.74  ? 430 LEU A N    1 
ATOM   6498 C CA   . LEU A 1 430 ? 93.125  94.020  90.693  1.00 93.74  ? 430 LEU A CA   1 
ATOM   6499 C C    . LEU A 1 430 ? 93.688  95.257  91.385  1.00 93.74  ? 430 LEU A C    1 
ATOM   6500 O O    . LEU A 1 430 ? 94.868  95.289  91.760  1.00 93.74  ? 430 LEU A O    1 
ATOM   6501 C CB   . LEU A 1 430 ? 92.952  94.287  89.195  1.00 93.74  ? 430 LEU A CB   1 
ATOM   6502 C CG   . LEU A 1 430 ? 92.377  93.180  88.303  1.00 93.74  ? 430 LEU A CG   1 
ATOM   6503 C CD1  . LEU A 1 430 ? 90.854  93.168  88.328  1.00 93.74  ? 430 LEU A CD1  1 
ATOM   6504 C CD2  . LEU A 1 430 ? 92.881  93.335  86.874  1.00 93.74  ? 430 LEU A CD2  1 
ATOM   6505 H H    . LEU A 1 430 ? 91.177  93.679  90.760  1.00 93.74  ? 430 LEU A H    1 
ATOM   6506 H HA   . LEU A 1 430 ? 93.766  93.300  90.798  1.00 93.74  ? 430 LEU A HA   1 
ATOM   6507 H HB2  . LEU A 1 430 ? 92.375  95.061  89.096  1.00 93.74  ? 430 LEU A HB2  1 
ATOM   6508 H HB3  . LEU A 1 430 ? 93.827  94.503  88.836  1.00 93.74  ? 430 LEU A HB3  1 
ATOM   6509 H HG   . LEU A 1 430 ? 92.685  92.322  88.634  1.00 93.74  ? 430 LEU A HG   1 
ATOM   6510 H HD11 . LEU A 1 430 ? 90.533  92.686  87.549  1.00 93.74  ? 430 LEU A HD11 1 
ATOM   6511 H HD12 . LEU A 1 430 ? 90.550  92.726  89.134  1.00 93.74  ? 430 LEU A HD12 1 
ATOM   6512 H HD13 . LEU A 1 430 ? 90.528  94.081  88.304  1.00 93.74  ? 430 LEU A HD13 1 
ATOM   6513 H HD21 . LEU A 1 430 ? 92.484  92.642  86.323  1.00 93.74  ? 430 LEU A HD21 1 
ATOM   6514 H HD22 . LEU A 1 430 ? 92.624  94.209  86.542  1.00 93.74  ? 430 LEU A HD22 1 
ATOM   6515 H HD23 . LEU A 1 430 ? 93.847  93.249  86.867  1.00 93.74  ? 430 LEU A HD23 1 
ATOM   6516 N N    . ASN A 1 431 ? 92.847  96.276  91.578  1.00 90.92  ? 431 ASN A N    1 
ATOM   6517 C CA   . ASN A 1 431 ? 93.339  97.601  91.946  1.00 90.92  ? 431 ASN A CA   1 
ATOM   6518 C C    . ASN A 1 431 ? 94.103  97.572  93.264  1.00 90.92  ? 431 ASN A C    1 
ATOM   6519 O O    . ASN A 1 431 ? 95.130  98.247  93.408  1.00 90.92  ? 431 ASN A O    1 
ATOM   6520 C CB   . ASN A 1 431 ? 92.168  98.581  92.021  1.00 90.92  ? 431 ASN A CB   1 
ATOM   6521 C CG   . ASN A 1 431 ? 92.615  100.018 92.205  1.00 90.92  ? 431 ASN A CG   1 
ATOM   6522 O OD1  . ASN A 1 431 ? 93.401  100.328 93.099  1.00 90.92  ? 431 ASN A OD1  1 
ATOM   6523 N ND2  . ASN A 1 431 ? 92.114  100.904 91.351  1.00 90.92  ? 431 ASN A ND2  1 
ATOM   6524 H H    . ASN A 1 431 ? 91.991  96.224  91.503  1.00 90.92  ? 431 ASN A H    1 
ATOM   6525 H HA   . ASN A 1 431 ? 93.946  97.913  91.256  1.00 90.92  ? 431 ASN A HA   1 
ATOM   6526 H HB2  . ASN A 1 431 ? 91.660  98.529  91.196  1.00 90.92  ? 431 ASN A HB2  1 
ATOM   6527 H HB3  . ASN A 1 431 ? 91.603  98.344  92.773  1.00 90.92  ? 431 ASN A HB3  1 
ATOM   6528 H HD21 . ASN A 1 431 ? 92.335  101.733 91.410  1.00 90.92  ? 431 ASN A HD21 1 
ATOM   6529 H HD22 . ASN A 1 431 ? 91.567  100.649 90.738  1.00 90.92  ? 431 ASN A HD22 1 
ATOM   6530 N N    . ILE A 1 432 ? 93.620  96.805  94.242  1.00 85.56  ? 432 ILE A N    1 
ATOM   6531 C CA   . ILE A 1 432 ? 94.291  96.760  95.538  1.00 85.56  ? 432 ILE A CA   1 
ATOM   6532 C C    . ILE A 1 432 ? 95.709  96.221  95.376  1.00 85.56  ? 432 ILE A C    1 
ATOM   6533 O O    . ILE A 1 432 ? 96.675  96.784  95.906  1.00 85.56  ? 432 ILE A O    1 
ATOM   6534 C CB   . ILE A 1 432 ? 93.479  95.917  96.539  1.00 85.56  ? 432 ILE A CB   1 
ATOM   6535 C CG1  . ILE A 1 432 ? 92.011  96.351  96.553  1.00 85.56  ? 432 ILE A CG1  1 
ATOM   6536 C CG2  . ILE A 1 432 ? 94.063  96.051  97.935  1.00 85.56  ? 432 ILE A CG2  1 
ATOM   6537 C CD1  . ILE A 1 432 ? 91.075  95.396  95.832  1.00 85.56  ? 432 ILE A CD1  1 
ATOM   6538 H H    . ILE A 1 432 ? 92.921  96.309  94.177  1.00 85.56  ? 432 ILE A H    1 
ATOM   6539 H HA   . ILE A 1 432 ? 94.353  97.661  95.890  1.00 85.56  ? 432 ILE A HA   1 
ATOM   6540 H HB   . ILE A 1 432 ? 93.526  94.986  96.270  1.00 85.56  ? 432 ILE A HB   1 
ATOM   6541 H HG12 . ILE A 1 432 ? 91.714  96.412  97.474  1.00 85.56  ? 432 ILE A HG12 1 
ATOM   6542 H HG13 . ILE A 1 432 ? 91.934  97.220  96.128  1.00 85.56  ? 432 ILE A HG13 1 
ATOM   6543 H HG21 . ILE A 1 432 ? 93.510  95.553  98.558  1.00 85.56  ? 432 ILE A HG21 1 
ATOM   6544 H HG22 . ILE A 1 432 ? 94.965  95.696  97.939  1.00 85.56  ? 432 ILE A HG22 1 
ATOM   6545 H HG23 . ILE A 1 432 ? 94.075  96.989  98.181  1.00 85.56  ? 432 ILE A HG23 1 
ATOM   6546 H HD11 . ILE A 1 432 ? 90.212  95.826  95.719  1.00 85.56  ? 432 ILE A HD11 1 
ATOM   6547 H HD12 . ILE A 1 432 ? 91.448  95.172  94.967  1.00 85.56  ? 432 ILE A HD12 1 
ATOM   6548 H HD13 . ILE A 1 432 ? 90.975  94.592  96.365  1.00 85.56  ? 432 ILE A HD13 1 
ATOM   6549 N N    . THR A 1 433 ? 95.854  95.123  94.632  1.00 82.56  ? 433 THR A N    1 
ATOM   6550 C CA   . THR A 1 433 ? 97.174  94.532  94.437  1.00 82.56  ? 433 THR A CA   1 
ATOM   6551 C C    . THR A 1 433 ? 98.086  95.457  93.640  1.00 82.56  ? 433 THR A C    1 
ATOM   6552 O O    . THR A 1 433 ? 99.285  95.554  93.927  1.00 82.56  ? 433 THR A O    1 
ATOM   6553 C CB   . THR A 1 433 ? 97.043  93.180  93.741  1.00 82.56  ? 433 THR A CB   1 
ATOM   6554 O OG1  . THR A 1 433 ? 96.275  93.329  92.540  1.00 82.56  ? 433 THR A OG1  1 
ATOM   6555 C CG2  . THR A 1 433 ? 96.367  92.169  94.660  1.00 82.56  ? 433 THR A CG2  1 
ATOM   6556 H H    . THR A 1 433 ? 95.212  94.710  94.235  1.00 82.56  ? 433 THR A H    1 
ATOM   6557 H HA   . THR A 1 433 ? 97.583  94.385  95.305  1.00 82.56  ? 433 THR A HA   1 
ATOM   6558 H HB   . THR A 1 433 ? 97.926  92.847  93.518  1.00 82.56  ? 433 THR A HB   1 
ATOM   6559 H HG1  . THR A 1 433 ? 95.490  93.564  92.725  1.00 82.56  ? 433 THR A HG1  1 
ATOM   6560 H HG21 . THR A 1 433 ? 96.393  91.286  94.259  1.00 82.56  ? 433 THR A HG21 1 
ATOM   6561 H HG22 . THR A 1 433 ? 96.826  92.141  95.514  1.00 82.56  ? 433 THR A HG22 1 
ATOM   6562 H HG23 . THR A 1 433 ? 95.442  92.421  94.808  1.00 82.56  ? 433 THR A HG23 1 
ATOM   6563 N N    . VAL A 1 434 ? 97.548  96.131  92.623  1.00 80.95  ? 434 VAL A N    1 
ATOM   6564 C CA   . VAL A 1 434 ? 98.365  97.074  91.863  1.00 80.95  ? 434 VAL A CA   1 
ATOM   6565 C C    . VAL A 1 434 ? 98.867  98.188  92.776  1.00 80.95  ? 434 VAL A C    1 
ATOM   6566 O O    . VAL A 1 434 ? 100.036 98.601  92.707  1.00 80.95  ? 434 VAL A O    1 
ATOM   6567 C CB   . VAL A 1 434 ? 97.571  97.632  90.668  1.00 80.95  ? 434 VAL A CB   1 
ATOM   6568 C CG1  . VAL A 1 434 ? 98.409  98.643  89.894  1.00 80.95  ? 434 VAL A CG1  1 
ATOM   6569 C CG2  . VAL A 1 434 ? 97.124  96.506  89.756  1.00 80.95  ? 434 VAL A CG2  1 
ATOM   6570 H H    . VAL A 1 434 ? 96.732  96.065  92.360  1.00 80.95  ? 434 VAL A H    1 
ATOM   6571 H HA   . VAL A 1 434 ? 99.139  96.606  91.508  1.00 80.95  ? 434 VAL A HA   1 
ATOM   6572 H HB   . VAL A 1 434 ? 96.778  98.082  90.995  1.00 80.95  ? 434 VAL A HB   1 
ATOM   6573 H HG11 . VAL A 1 434 ? 97.973  98.831  89.048  1.00 80.95  ? 434 VAL A HG11 1 
ATOM   6574 H HG12 . VAL A 1 434 ? 98.485  99.460  90.410  1.00 80.95  ? 434 VAL A HG12 1 
ATOM   6575 H HG13 . VAL A 1 434 ? 99.288  98.265  89.736  1.00 80.95  ? 434 VAL A HG13 1 
ATOM   6576 H HG21 . VAL A 1 434 ? 96.573  96.875  89.048  1.00 80.95  ? 434 VAL A HG21 1 
ATOM   6577 H HG22 . VAL A 1 434 ? 97.909  96.079  89.379  1.00 80.95  ? 434 VAL A HG22 1 
ATOM   6578 H HG23 . VAL A 1 434 ? 96.611  95.864  90.269  1.00 80.95  ? 434 VAL A HG23 1 
ATOM   6579 N N    . ALA A 1 435 ? 97.992  98.692  93.648  1.00 78.03  ? 435 ALA A N    1 
ATOM   6580 C CA   . ALA A 1 435 ? 98.415  99.708  94.602  1.00 78.03  ? 435 ALA A CA   1 
ATOM   6581 C C    . ALA A 1 435 ? 99.493  99.169  95.530  1.00 78.03  ? 435 ALA A C    1 
ATOM   6582 O O    . ALA A 1 435 ? 100.416 99.898  95.904  1.00 78.03  ? 435 ALA A O    1 
ATOM   6583 C CB   . ALA A 1 435 ? 97.217  100.204 95.406  1.00 78.03  ? 435 ALA A CB   1 
ATOM   6584 H H    . ALA A 1 435 ? 97.162  98.473  93.703  1.00 78.03  ? 435 ALA A H    1 
ATOM   6585 H HA   . ALA A 1 435 ? 98.785  100.462 94.117  1.00 78.03  ? 435 ALA A HA   1 
ATOM   6586 H HB1  . ALA A 1 435 ? 97.527  100.877 96.029  1.00 78.03  ? 435 ALA A HB1  1 
ATOM   6587 H HB2  . ALA A 1 435 ? 96.562  100.586 94.800  1.00 78.03  ? 435 ALA A HB2  1 
ATOM   6588 H HB3  . ALA A 1 435 ? 96.829  99.458  95.889  1.00 78.03  ? 435 ALA A HB3  1 
ATOM   6589 N N    . CYS A 1 436 ? 99.384  97.903  95.932  1.00 72.10  ? 436 CYS A N    1 
ATOM   6590 C CA   . CYS A 1 436 ? 100.450 97.301  96.729  1.00 72.10  ? 436 CYS A CA   1 
ATOM   6591 C C    . CYS A 1 436 ? 101.762 97.255  95.957  1.00 72.10  ? 436 CYS A C    1 
ATOM   6592 O O    . CYS A 1 436 ? 102.837 97.450  96.540  1.00 72.10  ? 436 CYS A O    1 
ATOM   6593 C CB   . CYS A 1 436 ? 100.046 95.897  97.174  1.00 72.10  ? 436 CYS A CB   1 
ATOM   6594 S SG   . CYS A 1 436 ? 98.746  95.868  98.433  1.00 72.10  ? 436 CYS A SG   1 
ATOM   6595 H H    . CYS A 1 436 ? 98.719  97.384  95.764  1.00 72.10  ? 436 CYS A H    1 
ATOM   6596 H HA   . CYS A 1 436 ? 100.591 97.839  97.524  1.00 72.10  ? 436 CYS A HA   1 
ATOM   6597 H HB2  . CYS A 1 436 ? 99.718  95.410  96.402  1.00 72.10  ? 436 CYS A HB2  1 
ATOM   6598 H HB3  . CYS A 1 436 ? 100.824 95.448  97.539  1.00 72.10  ? 436 CYS A HB3  1 
ATOM   6599 H HG   . CYS A 1 436 ? 98.501  94.729  98.718  1.00 72.10  ? 436 CYS A HG   1 
ATOM   6600 N N    . VAL A 1 437 ? 101.698 96.993  94.652  1.00 70.17  ? 437 VAL A N    1 
ATOM   6601 C CA   . VAL A 1 437 ? 102.909 97.013  93.832  1.00 70.17  ? 437 VAL A CA   1 
ATOM   6602 C C    . VAL A 1 437 ? 103.542 98.396  93.881  1.00 70.17  ? 437 VAL A C    1 
ATOM   6603 O O    . VAL A 1 437 ? 104.759 98.546  94.059  1.00 70.17  ? 437 VAL A O    1 
ATOM   6604 C CB   . VAL A 1 437 ? 102.590 96.593  92.385  1.00 70.17  ? 437 VAL A CB   1 
ATOM   6605 C CG1  . VAL A 1 437 ? 103.838 96.679  91.511  1.00 70.17  ? 437 VAL A CG1  1 
ATOM   6606 C CG2  . VAL A 1 437 ? 102.011 95.187  92.349  1.00 70.17  ? 437 VAL A CG2  1 
ATOM   6607 H H    . VAL A 1 437 ? 100.976 96.808  94.222  1.00 70.17  ? 437 VAL A H    1 
ATOM   6608 H HA   . VAL A 1 437 ? 103.548 96.381  94.196  1.00 70.17  ? 437 VAL A HA   1 
ATOM   6609 H HB   . VAL A 1 437 ? 101.927 97.199  92.019  1.00 70.17  ? 437 VAL A HB   1 
ATOM   6610 H HG11 . VAL A 1 437 ? 103.629 96.325  90.632  1.00 70.17  ? 437 VAL A HG11 1 
ATOM   6611 H HG12 . VAL A 1 437 ? 104.115 97.605  91.432  1.00 70.17  ? 437 VAL A HG12 1 
ATOM   6612 H HG13 . VAL A 1 437 ? 104.546 96.154  91.915  1.00 70.17  ? 437 VAL A HG13 1 
ATOM   6613 H HG21 . VAL A 1 437 ? 102.256 94.767  91.510  1.00 70.17  ? 437 VAL A HG21 1 
ATOM   6614 H HG22 . VAL A 1 437 ? 102.370 94.676  93.091  1.00 70.17  ? 437 VAL A HG22 1 
ATOM   6615 H HG23 . VAL A 1 437 ? 101.047 95.242  92.422  1.00 70.17  ? 437 VAL A HG23 1 
ATOM   6616 N N    . GLY A 1 438 ? 102.718 99.429  93.722  1.00 68.67  ? 438 GLY A N    1 
ATOM   6617 C CA   . GLY A 1 438 ? 103.233 100.786 93.818  1.00 68.67  ? 438 GLY A CA   1 
ATOM   6618 C C    . GLY A 1 438 ? 103.809 101.092 95.189  1.00 68.67  ? 438 GLY A C    1 
ATOM   6619 O O    . GLY A 1 438 ? 104.821 101.787 95.310  1.00 68.67  ? 438 GLY A O    1 
ATOM   6620 H H    . GLY A 1 438 ? 101.876 99.371  93.559  1.00 68.67  ? 438 GLY A H    1 
ATOM   6621 H HA2  . GLY A 1 438 ? 103.937 100.907 93.161  1.00 68.67  ? 438 GLY A HA2  1 
ATOM   6622 H HA3  . GLY A 1 438 ? 102.524 101.422 93.630  1.00 68.67  ? 438 GLY A HA3  1 
ATOM   6623 N N    . ARG A 1 439 ? 103.165 100.585 96.241  1.00 61.49  ? 439 ARG A N    1 
ATOM   6624 C CA   . ARG A 1 439 ? 103.674 100.768 97.597  1.00 61.49  ? 439 ARG A CA   1 
ATOM   6625 C C    . ARG A 1 439 ? 105.070 100.178 97.737  1.00 61.49  ? 439 ARG A C    1 
ATOM   6626 O O    . ARG A 1 439 ? 105.975 100.809 98.298  1.00 61.49  ? 439 ARG A O    1 
ATOM   6627 C CB   . ARG A 1 439 ? 102.723 100.118 98.601  1.00 61.49  ? 439 ARG A CB   1 
ATOM   6628 C CG   . ARG A 1 439 ? 101.502 100.949 98.954  1.00 61.49  ? 439 ARG A CG   1 
ATOM   6629 C CD   . ARG A 1 439 ? 101.828 102.061 99.935  1.00 61.49  ? 439 ARG A CD   1 
ATOM   6630 N NE   . ARG A 1 439 ? 102.410 101.550 101.170 1.00 61.49  ? 439 ARG A NE   1 
ATOM   6631 C CZ   . ARG A 1 439 ? 102.529 102.253 102.287 1.00 61.49  ? 439 ARG A CZ   1 
ATOM   6632 N NH1  . ARG A 1 439 ? 102.087 103.498 102.372 1.00 61.49  ? 439 ARG A NH1  1 
ATOM   6633 N NH2  . ARG A 1 439 ? 103.101 101.693 103.349 1.00 61.49  ? 439 ARG A NH2  1 
ATOM   6634 H H    . ARG A 1 439 ? 102.435 100.133 96.193  1.00 61.49  ? 439 ARG A H    1 
ATOM   6635 H HA   . ARG A 1 439 ? 103.725 101.716 97.794  1.00 61.49  ? 439 ARG A HA   1 
ATOM   6636 H HB2  . ARG A 1 439 ? 102.403 99.284  98.222  1.00 61.49  ? 439 ARG A HB2  1 
ATOM   6637 H HB3  . ARG A 1 439 ? 103.211 99.935  99.417  1.00 61.49  ? 439 ARG A HB3  1 
ATOM   6638 H HG2  . ARG A 1 439 ? 101.145 101.353 98.147  1.00 61.49  ? 439 ARG A HG2  1 
ATOM   6639 H HG3  . ARG A 1 439 ? 100.837 100.375 99.364  1.00 61.49  ? 439 ARG A HG3  1 
ATOM   6640 H HD2  . ARG A 1 439 ? 102.463 102.671 99.529  1.00 61.49  ? 439 ARG A HD2  1 
ATOM   6641 H HD3  . ARG A 1 439 ? 101.010 102.532 100.160 1.00 61.49  ? 439 ARG A HD3  1 
ATOM   6642 H HE   . ARG A 1 439 ? 102.563 100.705 101.217 1.00 61.49  ? 439 ARG A HE   1 
ATOM   6643 H HH11 . ARG A 1 439 ? 101.713 103.871 101.694 1.00 61.49  ? 439 ARG A HH11 1 
ATOM   6644 H HH12 . ARG A 1 439 ? 102.172 103.934 103.108 1.00 61.49  ? 439 ARG A HH12 1 
ATOM   6645 H HH21 . ARG A 1 439 ? 103.391 100.884 103.304 1.00 61.49  ? 439 ARG A HH21 1 
ATOM   6646 H HH22 . ARG A 1 439 ? 103.182 102.139 104.080 1.00 61.49  ? 439 ARG A HH22 1 
ATOM   6647 N N    . MET A 1 440 ? 105.253 98.949  97.253  1.00 57.38  ? 440 MET A N    1 
ATOM   6648 C CA   . MET A 1 440 ? 106.568 98.323  97.327  1.00 57.38  ? 440 MET A CA   1 
ATOM   6649 C C    . MET A 1 440 ? 107.591 99.118  96.527  1.00 57.38  ? 440 MET A C    1 
ATOM   6650 O O    . MET A 1 440 ? 108.730 99.314  96.975  1.00 57.38  ? 440 MET A O    1 
ATOM   6651 C CB   . MET A 1 440 ? 106.490 96.882  96.829  1.00 57.38  ? 440 MET A CB   1 
ATOM   6652 C CG   . MET A 1 440 ? 107.797 96.124  96.934  1.00 57.38  ? 440 MET A CG   1 
ATOM   6653 S SD   . MET A 1 440 ? 107.551 94.366  97.234  1.00 57.38  ? 440 MET A SD   1 
ATOM   6654 C CE   . MET A 1 440 ? 106.368 93.967  95.953  1.00 57.38  ? 440 MET A CE   1 
ATOM   6655 H H    . MET A 1 440 ? 104.645 98.466  96.884  1.00 57.38  ? 440 MET A H    1 
ATOM   6656 H HA   . MET A 1 440 ? 106.852 98.300  98.255  1.00 57.38  ? 440 MET A HA   1 
ATOM   6657 H HB2  . MET A 1 440 ? 105.827 96.405  97.354  1.00 57.38  ? 440 MET A HB2  1 
ATOM   6658 H HB3  . MET A 1 440 ? 106.226 96.888  95.896  1.00 57.38  ? 440 MET A HB3  1 
ATOM   6659 H HG2  . MET A 1 440 ? 108.287 96.223  96.103  1.00 57.38  ? 440 MET A HG2  1 
ATOM   6660 H HG3  . MET A 1 440 ? 108.314 96.486  97.670  1.00 57.38  ? 440 MET A HG3  1 
ATOM   6661 H HE1  . MET A 1 440 ? 106.265 93.003  95.909  1.00 57.38  ? 440 MET A HE1  1 
ATOM   6662 H HE2  . MET A 1 440 ? 105.518 94.381  96.170  1.00 57.38  ? 440 MET A HE2  1 
ATOM   6663 H HE3  . MET A 1 440 ? 106.696 94.303  95.104  1.00 57.38  ? 440 MET A HE3  1 
ATOM   6664 N N    . GLY A 1 441 ? 107.201 99.592  95.343  1.00 58.94  ? 441 GLY A N    1 
ATOM   6665 C CA   . GLY A 1 441 ? 108.107 100.420 94.564  1.00 58.94  ? 441 GLY A CA   1 
ATOM   6666 C C    . GLY A 1 441 ? 108.542 101.664 95.316  1.00 58.94  ? 441 GLY A C    1 
ATOM   6667 O O    . GLY A 1 441 ? 109.727 102.006 95.342  1.00 58.94  ? 441 GLY A O    1 
ATOM   6668 H H    . GLY A 1 441 ? 106.434 99.453  94.979  1.00 58.94  ? 441 GLY A H    1 
ATOM   6669 H HA2  . GLY A 1 441 ? 108.897 99.907  94.333  1.00 58.94  ? 441 GLY A HA2  1 
ATOM   6670 H HA3  . GLY A 1 441 ? 107.670 100.695 93.743  1.00 58.94  ? 441 GLY A HA3  1 
ATOM   6671 N N    . ILE A 1 442 ? 107.591 102.347 95.953  1.00 60.14  ? 442 ILE A N    1 
ATOM   6672 C CA   . ILE A 1 442 ? 107.912 103.576 96.670  1.00 60.14  ? 442 ILE A CA   1 
ATOM   6673 C C    . ILE A 1 442 ? 108.805 103.286 97.868  1.00 60.14  ? 442 ILE A C    1 
ATOM   6674 O O    . ILE A 1 442 ? 109.721 104.058 98.173  1.00 60.14  ? 442 ILE A O    1 
ATOM   6675 C CB   . ILE A 1 442 ? 106.622 104.296 97.095  1.00 60.14  ? 442 ILE A CB   1 
ATOM   6676 C CG1  . ILE A 1 442 ? 105.892 104.854 95.872  1.00 60.14  ? 442 ILE A CG1  1 
ATOM   6677 C CG2  . ILE A 1 442 ? 106.935 105.399 98.084  1.00 60.14  ? 442 ILE A CG2  1 
ATOM   6678 C CD1  . ILE A 1 442 ? 106.653 105.926 95.114  1.00 60.14  ? 442 ILE A CD1  1 
ATOM   6679 H H    . ILE A 1 442 ? 106.761 102.123 95.983  1.00 60.14  ? 442 ILE A H    1 
ATOM   6680 H HA   . ILE A 1 442 ? 108.408 104.162 96.079  1.00 60.14  ? 442 ILE A HA   1 
ATOM   6681 H HB   . ILE A 1 442 ? 106.042 103.652 97.529  1.00 60.14  ? 442 ILE A HB   1 
ATOM   6682 H HG12 . ILE A 1 442 ? 105.714 104.127 95.256  1.00 60.14  ? 442 ILE A HG12 1 
ATOM   6683 H HG13 . ILE A 1 442 ? 105.057 105.246 96.168  1.00 60.14  ? 442 ILE A HG13 1 
ATOM   6684 H HG21 . ILE A 1 442 ? 106.175 105.999 98.120  1.00 60.14  ? 442 ILE A HG21 1 
ATOM   6685 H HG22 . ILE A 1 442 ? 107.088 105.010 98.959  1.00 60.14  ? 442 ILE A HG22 1 
ATOM   6686 H HG23 . ILE A 1 442 ? 107.723 105.880 97.787  1.00 60.14  ? 442 ILE A HG23 1 
ATOM   6687 H HD11 . ILE A 1 442 ? 106.081 106.265 94.409  1.00 60.14  ? 442 ILE A HD11 1 
ATOM   6688 H HD12 . ILE A 1 442 ? 106.887 106.645 95.720  1.00 60.14  ? 442 ILE A HD12 1 
ATOM   6689 H HD13 . ILE A 1 442 ? 107.455 105.541 94.728  1.00 60.14  ? 442 ILE A HD13 1 
ATOM   6690 N N    . THR A 1 443 ? 108.542 102.193 98.585  1.00 54.59  ? 443 THR A N    1 
ATOM   6691 C CA   . THR A 1 443 ? 109.393 101.853 99.722  1.00 54.59  ? 443 THR A CA   1 
ATOM   6692 C C    . THR A 1 443 ? 110.821 101.573 99.269  1.00 54.59  ? 443 THR A C    1 
ATOM   6693 O O    . THR A 1 443 ? 111.789 102.021 99.906  1.00 54.59  ? 443 THR A O    1 
ATOM   6694 C CB   . THR A 1 443 ? 108.821 100.650 100.467 1.00 54.59  ? 443 THR A CB   1 
ATOM   6695 O OG1  . THR A 1 443 ? 108.640 99.561  99.555  1.00 54.59  ? 443 THR A OG1  1 
ATOM   6696 C CG2  . THR A 1 443 ? 107.488 101.003 101.101 1.00 54.59  ? 443 THR A CG2  1 
ATOM   6697 H H    . THR A 1 443 ? 107.896 101.646 98.437  1.00 54.59  ? 443 THR A H    1 
ATOM   6698 H HA   . THR A 1 443 ? 109.414 102.604 100.335 1.00 54.59  ? 443 THR A HA   1 
ATOM   6699 H HB   . THR A 1 443 ? 109.434 100.383 101.169 1.00 54.59  ? 443 THR A HB   1 
ATOM   6700 H HG1  . THR A 1 443 ? 109.386 99.278  99.293  1.00 54.59  ? 443 THR A HG1  1 
ATOM   6701 H HG21 . THR A 1 443 ? 106.970 100.197 101.248 1.00 54.59  ? 443 THR A HG21 1 
ATOM   6702 H HG22 . THR A 1 443 ? 107.630 101.448 101.951 1.00 54.59  ? 443 THR A HG22 1 
ATOM   6703 H HG23 . THR A 1 443 ? 106.985 101.592 100.516 1.00 54.59  ? 443 THR A HG23 1 
ATOM   6704 N N    . ILE A 1 444 ? 110.975 100.834 98.168  1.00 52.55  ? 444 ILE A N    1 
ATOM   6705 C CA   . ILE A 1 444 ? 112.311 100.586 97.637  1.00 52.55  ? 444 ILE A CA   1 
ATOM   6706 C C    . ILE A 1 444 ? 112.979 101.901 97.266  1.00 52.55  ? 444 ILE A C    1 
ATOM   6707 O O    . ILE A 1 444 ? 114.169 102.107 97.534  1.00 52.55  ? 444 ILE A O    1 
ATOM   6708 C CB   . ILE A 1 444 ? 112.246 99.625  96.438  1.00 52.55  ? 444 ILE A CB   1 
ATOM   6709 C CG1  . ILE A 1 444 ? 111.837 98.230  96.911  1.00 52.55  ? 444 ILE A CG1  1 
ATOM   6710 C CG2  . ILE A 1 444 ? 113.588 99.579  95.733  1.00 52.55  ? 444 ILE A CG2  1 
ATOM   6711 C CD1  . ILE A 1 444 ? 111.502 97.269  95.792  1.00 52.55  ? 444 ILE A CD1  1 
ATOM   6712 H H    . ILE A 1 444 ? 110.335 100.475 97.719  1.00 52.55  ? 444 ILE A H    1 
ATOM   6713 H HA   . ILE A 1 444 ? 112.848 100.165 98.326  1.00 52.55  ? 444 ILE A HA   1 
ATOM   6714 H HB   . ILE A 1 444 ? 111.578 99.949  95.814  1.00 52.55  ? 444 ILE A HB   1 
ATOM   6715 H HG12 . ILE A 1 444 ? 112.570 97.846  97.418  1.00 52.55  ? 444 ILE A HG12 1 
ATOM   6716 H HG13 . ILE A 1 444 ? 111.053 98.309  97.477  1.00 52.55  ? 444 ILE A HG13 1 
ATOM   6717 H HG21 . ILE A 1 444 ? 113.626 98.797  95.163  1.00 52.55  ? 444 ILE A HG21 1 
ATOM   6718 H HG22 . ILE A 1 444 ? 113.692 100.379 95.195  1.00 52.55  ? 444 ILE A HG22 1 
ATOM   6719 H HG23 . ILE A 1 444 ? 114.292 99.534  96.400  1.00 52.55  ? 444 ILE A HG23 1 
ATOM   6720 H HD11 . ILE A 1 444 ? 111.096 96.474  96.172  1.00 52.55  ? 444 ILE A HD11 1 
ATOM   6721 H HD12 . ILE A 1 444 ? 110.879 97.698  95.184  1.00 52.55  ? 444 ILE A HD12 1 
ATOM   6722 H HD13 . ILE A 1 444 ? 112.315 97.031  95.320  1.00 52.55  ? 444 ILE A HD13 1 
ATOM   6723 N N    . VAL A 1 445 ? 112.230 102.812 96.642  1.00 55.02  ? 445 VAL A N    1 
ATOM   6724 C CA   . VAL A 1 445 ? 112.802 104.104 96.276  1.00 55.02  ? 445 VAL A CA   1 
ATOM   6725 C C    . VAL A 1 445 ? 113.294 104.835 97.518  1.00 55.02  ? 445 VAL A C    1 
ATOM   6726 O O    . VAL A 1 445 ? 114.407 105.371 97.541  1.00 55.02  ? 445 VAL A O    1 
ATOM   6727 C CB   . VAL A 1 445 ? 111.779 104.952 95.500  1.00 55.02  ? 445 VAL A CB   1 
ATOM   6728 C CG1  . VAL A 1 445 ? 112.258 106.393 95.401  1.00 55.02  ? 445 VAL A CG1  1 
ATOM   6729 C CG2  . VAL A 1 445 ? 111.550 104.374 94.115  1.00 55.02  ? 445 VAL A CG2  1 
ATOM   6730 H H    . VAL A 1 445 ? 111.404 102.708 96.425  1.00 55.02  ? 445 VAL A H    1 
ATOM   6731 H HA   . VAL A 1 445 ? 113.566 103.956 95.697  1.00 55.02  ? 445 VAL A HA   1 
ATOM   6732 H HB   . VAL A 1 445 ? 110.935 104.947 95.977  1.00 55.02  ? 445 VAL A HB   1 
ATOM   6733 H HG11 . VAL A 1 445 ? 111.782 106.832 94.680  1.00 55.02  ? 445 VAL A HG11 1 
ATOM   6734 H HG12 . VAL A 1 445 ? 112.078 106.848 96.239  1.00 55.02  ? 445 VAL A HG12 1 
ATOM   6735 H HG13 . VAL A 1 445 ? 113.211 106.398 95.217  1.00 55.02  ? 445 VAL A HG13 1 
ATOM   6736 H HG21 . VAL A 1 445 ? 110.864 104.894 93.667  1.00 55.02  ? 445 VAL A HG21 1 
ATOM   6737 H HG22 . VAL A 1 445 ? 112.379 104.418 93.614  1.00 55.02  ? 445 VAL A HG22 1 
ATOM   6738 H HG23 . VAL A 1 445 ? 111.263 103.452 94.200  1.00 55.02  ? 445 VAL A HG23 1 
ATOM   6739 N N    . PHE A 1 446 ? 112.471 104.875 98.567  1.00 54.11  ? 446 PHE A N    1 
ATOM   6740 C CA   . PHE A 1 446 ? 112.865 105.580 99.785  1.00 54.11  ? 446 PHE A CA   1 
ATOM   6741 C C    . PHE A 1 446 ? 114.163 105.014 100.344 1.00 54.11  ? 446 PHE A C    1 
ATOM   6742 O O    . PHE A 1 446 ? 115.125 105.753 100.598 1.00 54.11  ? 446 PHE A O    1 
ATOM   6743 C CB   . PHE A 1 446 ? 111.761 105.481 100.842 1.00 54.11  ? 446 PHE A CB   1 
ATOM   6744 C CG   . PHE A 1 446 ? 110.765 106.610 100.813 1.00 54.11  ? 446 PHE A CG   1 
ATOM   6745 C CD1  . PHE A 1 446 ? 111.174 107.924 100.679 1.00 54.11  ? 446 PHE A CD1  1 
ATOM   6746 C CD2  . PHE A 1 446 ? 109.414 106.348 100.939 1.00 54.11  ? 446 PHE A CD2  1 
ATOM   6747 C CE1  . PHE A 1 446 ? 110.252 108.950 100.659 1.00 54.11  ? 446 PHE A CE1  1 
ATOM   6748 C CE2  . PHE A 1 446 ? 108.491 107.370 100.919 1.00 54.11  ? 446 PHE A CE2  1 
ATOM   6749 C CZ   . PHE A 1 446 ? 108.911 108.672 100.780 1.00 54.11  ? 446 PHE A CZ   1 
ATOM   6750 H H    . PHE A 1 446 ? 111.693 104.509 98.599  1.00 54.11  ? 446 PHE A H    1 
ATOM   6751 H HA   . PHE A 1 446 ? 113.023 106.511 99.570  1.00 54.11  ? 446 PHE A HA   1 
ATOM   6752 H HB2  . PHE A 1 446 ? 111.274 104.654 100.706 1.00 54.11  ? 446 PHE A HB2  1 
ATOM   6753 H HB3  . PHE A 1 446 ? 112.173 105.478 101.721 1.00 54.11  ? 446 PHE A HB3  1 
ATOM   6754 H HD1  . PHE A 1 446 ? 112.079 108.119 100.597 1.00 54.11  ? 446 PHE A HD1  1 
ATOM   6755 H HD2  . PHE A 1 446 ? 109.123 105.470 101.032 1.00 54.11  ? 446 PHE A HD2  1 
ATOM   6756 H HE1  . PHE A 1 446 ? 110.537 109.831 100.565 1.00 54.11  ? 446 PHE A HE1  1 
ATOM   6757 H HE2  . PHE A 1 446 ? 107.584 107.180 101.000 1.00 54.11  ? 446 PHE A HE2  1 
ATOM   6758 H HZ   . PHE A 1 446 ? 108.288 109.363 100.766 1.00 54.11  ? 446 PHE A HZ   1 
ATOM   6759 N N    . GLN A 1 447 ? 114.207 103.696 100.540 1.00 51.29  ? 447 GLN A N    1 
ATOM   6760 C CA   . GLN A 1 447 ? 115.375 103.097 101.175 1.00 51.29  ? 447 GLN A CA   1 
ATOM   6761 C C    . GLN A 1 447 ? 116.625 103.292 100.323 1.00 51.29  ? 447 GLN A C    1 
ATOM   6762 O O    . GLN A 1 447 ? 117.695 103.646 100.838 1.00 51.29  ? 447 GLN A O    1 
ATOM   6763 C CB   . GLN A 1 447 ? 115.114 101.616 101.445 1.00 51.29  ? 447 GLN A CB   1 
ATOM   6764 C CG   . GLN A 1 447 ? 114.054 101.384 102.509 1.00 51.29  ? 447 GLN A CG   1 
ATOM   6765 C CD   . GLN A 1 447 ? 113.551 99.958  102.543 1.00 51.29  ? 447 GLN A CD   1 
ATOM   6766 O OE1  . GLN A 1 447 ? 112.371 99.714  102.785 1.00 51.29  ? 447 GLN A OE1  1 
ATOM   6767 N NE2  . GLN A 1 447 ? 114.445 99.005  102.306 1.00 51.29  ? 447 GLN A NE2  1 
ATOM   6768 H H    . GLN A 1 447 ? 113.589 103.140 100.319 1.00 51.29  ? 447 GLN A H    1 
ATOM   6769 H HA   . GLN A 1 447 ? 115.526 103.533 102.029 1.00 51.29  ? 447 GLN A HA   1 
ATOM   6770 H HB2  . GLN A 1 447 ? 114.811 101.196 100.625 1.00 51.29  ? 447 GLN A HB2  1 
ATOM   6771 H HB3  . GLN A 1 447 ? 115.937 101.201 101.746 1.00 51.29  ? 447 GLN A HB3  1 
ATOM   6772 H HG2  . GLN A 1 447 ? 114.432 101.588 103.379 1.00 51.29  ? 447 GLN A HG2  1 
ATOM   6773 H HG3  . GLN A 1 447 ? 113.298 101.965 102.334 1.00 51.29  ? 447 GLN A HG3  1 
ATOM   6774 H HE21 . GLN A 1 447 ? 114.203 98.180  102.316 1.00 51.29  ? 447 GLN A HE21 1 
ATOM   6775 H HE22 . GLN A 1 447 ? 115.263 99.209  102.142 1.00 51.29  ? 447 GLN A HE22 1 
ATOM   6776 N N    . MET A 1 448 ? 116.508 103.080 99.010  1.00 51.51  ? 448 MET A N    1 
ATOM   6777 C CA   . MET A 1 448 ? 117.672 103.223 98.143  1.00 51.51  ? 448 MET A CA   1 
ATOM   6778 C C    . MET A 1 448 ? 118.165 104.661 98.106  1.00 51.51  ? 448 MET A C    1 
ATOM   6779 O O    . MET A 1 448 ? 119.377 104.906 98.110  1.00 51.51  ? 448 MET A O    1 
ATOM   6780 C CB   . MET A 1 448 ? 117.339 102.738 96.735  1.00 51.51  ? 448 MET A CB   1 
ATOM   6781 C CG   . MET A 1 448 ? 117.477 101.247 96.562  1.00 51.51  ? 448 MET A CG   1 
ATOM   6782 S SD   . MET A 1 448 ? 119.170 100.711 96.831  1.00 51.51  ? 448 MET A SD   1 
ATOM   6783 C CE   . MET A 1 448 ? 119.993 101.499 95.457  1.00 51.51  ? 448 MET A CE   1 
ATOM   6784 H H    . MET A 1 448 ? 115.782 102.859 98.607  1.00 51.51  ? 448 MET A H    1 
ATOM   6785 H HA   . MET A 1 448 ? 118.383 102.667 98.496  1.00 51.51  ? 448 MET A HA   1 
ATOM   6786 H HB2  . MET A 1 448 ? 116.423 102.978 96.529  1.00 51.51  ? 448 MET A HB2  1 
ATOM   6787 H HB3  . MET A 1 448 ? 117.941 103.167 96.108  1.00 51.51  ? 448 MET A HB3  1 
ATOM   6788 H HG2  . MET A 1 448 ? 116.907 100.798 97.205  1.00 51.51  ? 448 MET A HG2  1 
ATOM   6789 H HG3  . MET A 1 448 ? 117.222 101.005 95.658  1.00 51.51  ? 448 MET A HG3  1 
ATOM   6790 H HE1  . MET A 1 448 ? 120.822 101.029 95.285  1.00 51.51  ? 448 MET A HE1  1 
ATOM   6791 H HE2  . MET A 1 448 ? 119.418 101.454 94.677  1.00 51.51  ? 448 MET A HE2  1 
ATOM   6792 H HE3  . MET A 1 448 ? 120.173 102.425 95.683  1.00 51.51  ? 448 MET A HE3  1 
ATOM   6793 N N    . VAL A 1 449 ? 117.248 105.628 98.047  1.00 50.86  ? 449 VAL A N    1 
ATOM   6794 C CA   . VAL A 1 449 ? 117.671 107.022 98.036  1.00 50.86  ? 449 VAL A CA   1 
ATOM   6795 C C    . VAL A 1 449 ? 118.408 107.349 99.320  1.00 50.86  ? 449 VAL A C    1 
ATOM   6796 O O    . VAL A 1 449 ? 119.460 107.999 99.300  1.00 50.86  ? 449 VAL A O    1 
ATOM   6797 C CB   . VAL A 1 449 ? 116.467 107.957 97.827  1.00 50.86  ? 449 VAL A CB   1 
ATOM   6798 C CG1  . VAL A 1 449 ? 116.888 109.399 98.033  1.00 50.86  ? 449 VAL A CG1  1 
ATOM   6799 C CG2  . VAL A 1 449 ? 115.887 107.771 96.441  1.00 50.86  ? 449 VAL A CG2  1 
ATOM   6800 H H    . VAL A 1 449 ? 116.397 105.506 98.015  1.00 50.86  ? 449 VAL A H    1 
ATOM   6801 H HA   . VAL A 1 449 ? 118.283 107.159 97.296  1.00 50.86  ? 449 VAL A HA   1 
ATOM   6802 H HB   . VAL A 1 449 ? 115.780 107.744 98.477  1.00 50.86  ? 449 VAL A HB   1 
ATOM   6803 H HG11 . VAL A 1 449 ? 116.220 109.980 97.635  1.00 50.86  ? 449 VAL A HG11 1 
ATOM   6804 H HG12 . VAL A 1 449 ? 116.957 109.580 98.983  1.00 50.86  ? 449 VAL A HG12 1 
ATOM   6805 H HG13 . VAL A 1 449 ? 117.746 109.541 97.603  1.00 50.86  ? 449 VAL A HG13 1 
ATOM   6806 H HG21 . VAL A 1 449 ? 115.003 108.170 96.414  1.00 50.86  ? 449 VAL A HG21 1 
ATOM   6807 H HG22 . VAL A 1 449 ? 116.466 108.207 95.797  1.00 50.86  ? 449 VAL A HG22 1 
ATOM   6808 H HG23 . VAL A 1 449 ? 115.828 106.824 96.245  1.00 50.86  ? 449 VAL A HG23 1 
ATOM   6809 N N    . CYS A 1 450 ? 117.879 106.901 100.459 1.00 49.09  ? 450 CYS A N    1 
ATOM   6810 C CA   . CYS A 1 450 ? 118.560 107.174 101.719 1.00 49.09  ? 450 CYS A CA   1 
ATOM   6811 C C    . CYS A 1 450 ? 119.969 106.593 101.707 1.00 49.09  ? 450 CYS A C    1 
ATOM   6812 O O    . CYS A 1 450 ? 120.940 107.275 102.058 1.00 49.09  ? 450 CYS A O    1 
ATOM   6813 C CB   . CYS A 1 450 ? 117.754 106.613 102.888 1.00 49.09  ? 450 CYS A CB   1 
ATOM   6814 S SG   . CYS A 1 450 ? 118.311 107.195 104.502 1.00 49.09  ? 450 CYS A SG   1 
ATOM   6815 H H    . CYS A 1 450 ? 117.150 106.450 100.528 1.00 49.09  ? 450 CYS A H    1 
ATOM   6816 H HA   . CYS A 1 450 ? 118.633 108.134 101.838 1.00 49.09  ? 450 CYS A HA   1 
ATOM   6817 H HB2  . CYS A 1 450 ? 116.826 106.873 102.782 1.00 49.09  ? 450 CYS A HB2  1 
ATOM   6818 H HB3  . CYS A 1 450 ? 117.827 105.645 102.882 1.00 49.09  ? 450 CYS A HB3  1 
ATOM   6819 H HG   . CYS A 1 450 ? 119.468 106.904 104.638 1.00 49.09  ? 450 CYS A HG   1 
ATOM   6820 N N    . LEU A 1 451 ? 120.103 105.335 101.279 1.00 50.11  ? 451 LEU A N    1 
ATOM   6821 C CA   . LEU A 1 451 ? 121.415 104.692 101.303 1.00 50.11  ? 451 LEU A CA   1 
ATOM   6822 C C    . LEU A 1 451 ? 122.400 105.410 100.388 1.00 50.11  ? 451 LEU A C    1 
ATOM   6823 O O    . LEU A 1 451 ? 123.531 105.716 100.789 1.00 50.11  ? 451 LEU A O    1 
ATOM   6824 C CB   . LEU A 1 451 ? 121.289 103.221 100.905 1.00 50.11  ? 451 LEU A CB   1 
ATOM   6825 C CG   . LEU A 1 451 ? 122.608 102.458 100.782 1.00 50.11  ? 451 LEU A CG   1 
ATOM   6826 C CD1  . LEU A 1 451 ? 123.387 102.514 102.081 1.00 50.11  ? 451 LEU A CD1  1 
ATOM   6827 C CD2  . LEU A 1 451 ? 122.355 101.019 100.377 1.00 50.11  ? 451 LEU A CD2  1 
ATOM   6828 H H    . LEU A 1 451 ? 119.465 104.844 100.977 1.00 50.11  ? 451 LEU A H    1 
ATOM   6829 H HA   . LEU A 1 451 ? 121.765 104.729 102.207 1.00 50.11  ? 451 LEU A HA   1 
ATOM   6830 H HB2  . LEU A 1 451 ? 120.752 102.767 101.574 1.00 50.11  ? 451 LEU A HB2  1 
ATOM   6831 H HB3  . LEU A 1 451 ? 120.843 103.172 100.045 1.00 50.11  ? 451 LEU A HB3  1 
ATOM   6832 H HG   . LEU A 1 451 ? 123.151 102.867 100.090 1.00 50.11  ? 451 LEU A HG   1 
ATOM   6833 H HD11 . LEU A 1 451 ? 124.156 101.927 102.012 1.00 50.11  ? 451 LEU A HD11 1 
ATOM   6834 H HD12 . LEU A 1 451 ? 123.680 103.425 102.236 1.00 50.11  ? 451 LEU A HD12 1 
ATOM   6835 H HD13 . LEU A 1 451 ? 122.813 102.222 102.806 1.00 50.11  ? 451 LEU A HD13 1 
ATOM   6836 H HD21 . LEU A 1 451 ? 123.204 100.552 100.329 1.00 50.11  ? 451 LEU A HD21 1 
ATOM   6837 H HD22 . LEU A 1 451 ? 121.784 100.600 101.040 1.00 50.11  ? 451 LEU A HD22 1 
ATOM   6838 H HD23 . LEU A 1 451 ? 121.920 101.007 99.510  1.00 50.11  ? 451 LEU A HD23 1 
ATOM   6839 N N    . VAL A 1 452 ? 121.991 105.689 99.149  1.00 51.53  ? 452 VAL A N    1 
ATOM   6840 C CA   . VAL A 1 452 ? 122.919 106.293 98.199  1.00 51.53  ? 452 VAL A CA   1 
ATOM   6841 C C    . VAL A 1 452 ? 123.299 107.696 98.649  1.00 51.53  ? 452 VAL A C    1 
ATOM   6842 O O    . VAL A 1 452 ? 124.464 108.100 98.544  1.00 51.53  ? 452 VAL A O    1 
ATOM   6843 C CB   . VAL A 1 452 ? 122.325 106.291 96.779  1.00 51.53  ? 452 VAL A CB   1 
ATOM   6844 C CG1  . VAL A 1 452 ? 121.127 107.211 96.693  1.00 51.53  ? 452 VAL A CG1  1 
ATOM   6845 C CG2  . VAL A 1 452 ? 123.380 106.698 95.767  1.00 51.53  ? 452 VAL A CG2  1 
ATOM   6846 H H    . VAL A 1 452 ? 121.201 105.541 98.842  1.00 51.53  ? 452 VAL A H    1 
ATOM   6847 H HA   . VAL A 1 452 ? 123.730 105.762 98.178  1.00 51.53  ? 452 VAL A HA   1 
ATOM   6848 H HB   . VAL A 1 452 ? 122.030 105.393 96.560  1.00 51.53  ? 452 VAL A HB   1 
ATOM   6849 H HG11 . VAL A 1 452 ? 120.675 107.059 95.849  1.00 51.53  ? 452 VAL A HG11 1 
ATOM   6850 H HG12 . VAL A 1 452 ? 120.527 107.014 97.428  1.00 51.53  ? 452 VAL A HG12 1 
ATOM   6851 H HG13 . VAL A 1 452 ? 121.426 108.132 96.745  1.00 51.53  ? 452 VAL A HG13 1 
ATOM   6852 H HG21 . VAL A 1 452 ? 123.005 106.626 94.875  1.00 51.53  ? 452 VAL A HG21 1 
ATOM   6853 H HG22 . VAL A 1 452 ? 123.649 107.614 95.938  1.00 51.53  ? 452 VAL A HG22 1 
ATOM   6854 H HG23 . VAL A 1 452 ? 124.144 106.106 95.852  1.00 51.53  ? 452 VAL A HG23 1 
ATOM   6855 N N    . ASN A 1 453 ? 122.335 108.462 99.164  1.00 51.18  ? 453 ASN A N    1 
ATOM   6856 C CA   . ASN A 1 453 ? 122.652 109.802 99.636  1.00 51.18  ? 453 ASN A CA   1 
ATOM   6857 C C    . ASN A 1 453 ? 123.629 109.750 100.799 1.00 51.18  ? 453 ASN A C    1 
ATOM   6858 O O    . ASN A 1 453 ? 124.558 110.561 100.873 1.00 51.18  ? 453 ASN A O    1 
ATOM   6859 C CB   . ASN A 1 453 ? 121.375 110.534 100.040 1.00 51.18  ? 453 ASN A CB   1 
ATOM   6860 C CG   . ASN A 1 453 ? 121.615 111.998 100.325 1.00 51.18  ? 453 ASN A CG   1 
ATOM   6861 O OD1  . ASN A 1 453 ? 122.571 112.362 101.007 1.00 51.18  ? 453 ASN A OD1  1 
ATOM   6862 N ND2  . ASN A 1 453 ? 120.753 112.850 99.792  1.00 51.18  ? 453 ASN A ND2  1 
ATOM   6863 H H    . ASN A 1 453 ? 121.510 108.232 99.250  1.00 51.18  ? 453 ASN A H    1 
ATOM   6864 H HA   . ASN A 1 453 ? 123.069 110.300 98.916  1.00 51.18  ? 453 ASN A HA   1 
ATOM   6865 H HB2  . ASN A 1 453 ? 120.732 110.470 99.318  1.00 51.18  ? 453 ASN A HB2  1 
ATOM   6866 H HB3  . ASN A 1 453 ? 121.016 110.126 100.844 1.00 51.18  ? 453 ASN A HB3  1 
ATOM   6867 H HD21 . ASN A 1 453 ? 120.851 113.693 99.923  1.00 51.18  ? 453 ASN A HD21 1 
ATOM   6868 H HD22 . ASN A 1 453 ? 120.098 112.560 99.317  1.00 51.18  ? 453 ASN A HD22 1 
ATOM   6869 N N    . ALA A 1 454 ? 123.442 108.802 101.720 1.00 51.09  ? 454 ALA A N    1 
ATOM   6870 C CA   . ALA A 1 454 ? 124.388 108.675 102.821 1.00 51.09  ? 454 ALA A CA   1 
ATOM   6871 C C    . ALA A 1 454 ? 125.779 108.341 102.303 1.00 51.09  ? 454 ALA A C    1 
ATOM   6872 O O    . ALA A 1 454 ? 126.778 108.883 102.789 1.00 51.09  ? 454 ALA A O    1 
ATOM   6873 C CB   . ALA A 1 454 ? 123.914 107.608 103.806 1.00 51.09  ? 454 ALA A CB   1 
ATOM   6874 H H    . ALA A 1 454 ? 122.795 108.235 101.727 1.00 51.09  ? 454 ALA A H    1 
ATOM   6875 H HA   . ALA A 1 454 ? 124.440 109.520 103.295 1.00 51.09  ? 454 ALA A HA   1 
ATOM   6876 H HB1  . ALA A 1 454 ? 124.558 107.537 104.528 1.00 51.09  ? 454 ALA A HB1  1 
ATOM   6877 H HB2  . ALA A 1 454 ? 123.048 107.867 104.159 1.00 51.09  ? 454 ALA A HB2  1 
ATOM   6878 H HB3  . ALA A 1 454 ? 123.843 106.759 103.342 1.00 51.09  ? 454 ALA A HB3  1 
ATOM   6879 N N    . GLU A 1 455 ? 125.864 107.461 101.307 1.00 54.92  ? 455 GLU A N    1 
ATOM   6880 C CA   . GLU A 1 455 ? 127.164 107.018 100.819 1.00 54.92  ? 455 GLU A CA   1 
ATOM   6881 C C    . GLU A 1 455 ? 127.875 108.058 99.962  1.00 54.92  ? 455 GLU A C    1 
ATOM   6882 O O    . GLU A 1 455 ? 129.105 108.015 99.864  1.00 54.92  ? 455 GLU A O    1 
ATOM   6883 C CB   . GLU A 1 455 ? 127.007 105.728 100.014 1.00 54.92  ? 455 GLU A CB   1 
ATOM   6884 C CG   . GLU A 1 455 ? 128.306 105.208 99.431  1.00 54.92  ? 455 GLU A CG   1 
ATOM   6885 C CD   . GLU A 1 455 ? 128.173 103.805 98.882  1.00 54.92  ? 455 GLU A CD   1 
ATOM   6886 O OE1  . GLU A 1 455 ? 127.032 103.305 98.794  1.00 54.92  ? 455 GLU A OE1  1 
ATOM   6887 O OE2  . GLU A 1 455 ? 129.211 103.199 98.545  1.00 54.92  ? 455 GLU A OE2  1 
ATOM   6888 H H    . GLU A 1 455 ? 125.192 107.110 100.902 1.00 54.92  ? 455 GLU A H    1 
ATOM   6889 H HA   . GLU A 1 455 ? 127.733 106.824 101.580 1.00 54.92  ? 455 GLU A HA   1 
ATOM   6890 H HB2  . GLU A 1 455 ? 126.645 105.040 100.594 1.00 54.92  ? 455 GLU A HB2  1 
ATOM   6891 H HB3  . GLU A 1 455 ? 126.397 105.892 99.278  1.00 54.92  ? 455 GLU A HB3  1 
ATOM   6892 H HG2  . GLU A 1 455 ? 128.584 105.786 98.703  1.00 54.92  ? 455 GLU A HG2  1 
ATOM   6893 H HG3  . GLU A 1 455 ? 128.983 105.197 100.125 1.00 54.92  ? 455 GLU A HG3  1 
ATOM   6894 N N    . LEU A 1 456 ? 127.145 108.983 99.340  1.00 56.01  ? 456 LEU A N    1 
ATOM   6895 C CA   . LEU A 1 456 ? 127.753 109.824 98.312  1.00 56.01  ? 456 LEU A CA   1 
ATOM   6896 C C    . LEU A 1 456 ? 128.472 111.045 98.877  1.00 56.01  ? 456 LEU A C    1 
ATOM   6897 O O    . LEU A 1 456 ? 129.406 111.548 98.244  1.00 56.01  ? 456 LEU A O    1 
ATOM   6898 C CB   . LEU A 1 456 ? 126.685 110.272 97.316  1.00 56.01  ? 456 LEU A CB   1 
ATOM   6899 C CG   . LEU A 1 456 ? 127.182 110.930 96.031  1.00 56.01  ? 456 LEU A CG   1 
ATOM   6900 C CD1  . LEU A 1 456 ? 128.035 109.966 95.222  1.00 56.01  ? 456 LEU A CD1  1 
ATOM   6901 C CD2  . LEU A 1 456 ? 126.000 111.417 95.211  1.00 56.01  ? 456 LEU A CD2  1 
ATOM   6902 H H    . LEU A 1 456 ? 126.313 109.141 99.490  1.00 56.01  ? 456 LEU A H    1 
ATOM   6903 H HA   . LEU A 1 456 ? 128.408 109.296 97.830  1.00 56.01  ? 456 LEU A HA   1 
ATOM   6904 H HB2  . LEU A 1 456 ? 126.170 109.492 97.056  1.00 56.01  ? 456 LEU A HB2  1 
ATOM   6905 H HB3  . LEU A 1 456 ? 126.102 110.907 97.759  1.00 56.01  ? 456 LEU A HB3  1 
ATOM   6906 H HG   . LEU A 1 456 ? 127.728 111.699 96.257  1.00 56.01  ? 456 LEU A HG   1 
ATOM   6907 H HD11 . LEU A 1 456 ? 128.164 110.331 94.333  1.00 56.01  ? 456 LEU A HD11 1 
ATOM   6908 H HD12 . LEU A 1 456 ? 128.892 109.856 95.662  1.00 56.01  ? 456 LEU A HD12 1 
ATOM   6909 H HD13 . LEU A 1 456 ? 127.578 109.112 95.164  1.00 56.01  ? 456 LEU A HD13 1 
ATOM   6910 H HD21 . LEU A 1 456 ? 126.329 111.830 94.397  1.00 56.01  ? 456 LEU A HD21 1 
ATOM   6911 H HD22 . LEU A 1 456 ? 125.435 110.660 94.992  1.00 56.01  ? 456 LEU A HD22 1 
ATOM   6912 H HD23 . LEU A 1 456 ? 125.500 112.064 95.732  1.00 56.01  ? 456 LEU A HD23 1 
ATOM   6913 N N    . TYR A 1 457 ? 128.064 111.542 100.039 1.00 55.92  ? 457 TYR A N    1 
ATOM   6914 C CA   . TYR A 1 457 ? 128.626 112.775 100.571 1.00 55.92  ? 457 TYR A CA   1 
ATOM   6915 C C    . TYR A 1 457 ? 129.964 112.533 101.265 1.00 55.92  ? 457 TYR A C    1 
ATOM   6916 O O    . TYR A 1 457 ? 130.316 111.395 101.582 1.00 55.92  ? 457 TYR A O    1 
ATOM   6917 C CB   . TYR A 1 457 ? 127.656 113.416 101.557 1.00 55.92  ? 457 TYR A CB   1 
ATOM   6918 C CG   . TYR A 1 457 ? 126.643 114.338 100.922 1.00 55.92  ? 457 TYR A CG   1 
ATOM   6919 C CD1  . TYR A 1 457 ? 127.018 115.582 100.442 1.00 55.92  ? 457 TYR A CD1  1 
ATOM   6920 C CD2  . TYR A 1 457 ? 125.312 113.971 100.819 1.00 55.92  ? 457 TYR A CD2  1 
ATOM   6921 C CE1  . TYR A 1 457 ? 126.100 116.428 99.868  1.00 55.92  ? 457 TYR A CE1  1 
ATOM   6922 C CE2  . TYR A 1 457 ? 124.385 114.811 100.247 1.00 55.92  ? 457 TYR A CE2  1 
ATOM   6923 C CZ   . TYR A 1 457 ? 124.784 116.039 99.773  1.00 55.92  ? 457 TYR A CZ   1 
ATOM   6924 O OH   . TYR A 1 457 ? 123.863 116.884 99.201  1.00 55.92  ? 457 TYR A OH   1 
ATOM   6925 H H    . TYR A 1 457 ? 127.462 111.183 100.538 1.00 55.92  ? 457 TYR A H    1 
ATOM   6926 H HA   . TYR A 1 457 ? 128.765 113.393 99.838  1.00 55.92  ? 457 TYR A HA   1 
ATOM   6927 H HB2  . TYR A 1 457 ? 127.169 112.713 102.015 1.00 55.92  ? 457 TYR A HB2  1 
ATOM   6928 H HB3  . TYR A 1 457 ? 128.164 113.934 102.200 1.00 55.92  ? 457 TYR A HB3  1 
ATOM   6929 H HD1  . TYR A 1 457 ? 127.907 115.847 100.504 1.00 55.92  ? 457 TYR A HD1  1 
ATOM   6930 H HD2  . TYR A 1 457 ? 125.040 113.141 101.139 1.00 55.92  ? 457 TYR A HD2  1 
ATOM   6931 H HE1  . TYR A 1 457 ? 126.366 117.259 99.547  1.00 55.92  ? 457 TYR A HE1  1 
ATOM   6932 H HE2  . TYR A 1 457 ? 123.495 114.551 100.181 1.00 55.92  ? 457 TYR A HE2  1 
ATOM   6933 H HH   . TYR A 1 457 ? 124.236 117.599 98.964  1.00 55.92  ? 457 TYR A HH   1 
ATOM   6934 N N    . PRO A 1 458 ? 130.735 113.593 101.508 1.00 58.68  ? 458 PRO A N    1 
ATOM   6935 C CA   . PRO A 1 458 ? 131.956 113.446 102.306 1.00 58.68  ? 458 PRO A CA   1 
ATOM   6936 C C    . PRO A 1 458 ? 131.637 113.049 103.737 1.00 58.68  ? 458 PRO A C    1 
ATOM   6937 O O    . PRO A 1 458 ? 130.552 113.320 104.256 1.00 58.68  ? 458 PRO A O    1 
ATOM   6938 C CB   . PRO A 1 458 ? 132.596 114.839 102.248 1.00 58.68  ? 458 PRO A CB   1 
ATOM   6939 C CG   . PRO A 1 458 ? 131.967 115.513 101.085 1.00 58.68  ? 458 PRO A CG   1 
ATOM   6940 C CD   . PRO A 1 458 ? 130.581 114.963 100.994 1.00 58.68  ? 458 PRO A CD   1 
ATOM   6941 H HA   . PRO A 1 458 ? 132.553 112.794 101.907 1.00 58.68  ? 458 PRO A HA   1 
ATOM   6942 H HB2  . PRO A 1 458 ? 132.405 115.321 103.068 1.00 58.68  ? 458 PRO A HB2  1 
ATOM   6943 H HB3  . PRO A 1 458 ? 133.554 114.753 102.118 1.00 58.68  ? 458 PRO A HB3  1 
ATOM   6944 H HG2  . PRO A 1 458 ? 131.945 116.470 101.237 1.00 58.68  ? 458 PRO A HG2  1 
ATOM   6945 H HG3  . PRO A 1 458 ? 132.469 115.307 100.280 1.00 58.68  ? 458 PRO A HG3  1 
ATOM   6946 H HD2  . PRO A 1 458 ? 129.978 115.472 101.558 1.00 58.68  ? 458 PRO A HD2  1 
ATOM   6947 H HD3  . PRO A 1 458 ? 130.286 114.954 100.071 1.00 58.68  ? 458 PRO A HD3  1 
ATOM   6948 N N    . THR A 1 459 ? 132.605 112.391 104.376 1.00 59.60  ? 459 THR A N    1 
ATOM   6949 C CA   . THR A 1 459 ? 132.385 111.882 105.725 1.00 59.60  ? 459 THR A CA   1 
ATOM   6950 C C    . THR A 1 459 ? 132.196 113.011 106.731 1.00 59.60  ? 459 THR A C    1 
ATOM   6951 O O    . THR A 1 459 ? 131.380 112.897 107.652 1.00 59.60  ? 459 THR A O    1 
ATOM   6952 C CB   . THR A 1 459 ? 133.550 110.987 106.149 1.00 59.60  ? 459 THR A CB   1 
ATOM   6953 O OG1  . THR A 1 459 ? 133.247 110.376 107.408 1.00 59.60  ? 459 THR A OG1  1 
ATOM   6954 C CG2  . THR A 1 459 ? 134.831 111.794 106.287 1.00 59.60  ? 459 THR A CG2  1 
ATOM   6955 H H    . THR A 1 459 ? 133.386 112.228 104.053 1.00 59.60  ? 459 THR A H    1 
ATOM   6956 H HA   . THR A 1 459 ? 131.577 111.349 105.728 1.00 59.60  ? 459 THR A HA   1 
ATOM   6957 H HB   . THR A 1 459 ? 133.690 110.299 105.480 1.00 59.60  ? 459 THR A HB   1 
ATOM   6958 H HG1  . THR A 1 459 ? 133.891 109.898 107.657 1.00 59.60  ? 459 THR A HG1  1 
ATOM   6959 H HG21 . THR A 1 459 ? 135.599 111.201 106.269 1.00 59.60  ? 459 THR A HG21 1 
ATOM   6960 H HG22 . THR A 1 459 ? 134.906 112.429 105.558 1.00 59.60  ? 459 THR A HG22 1 
ATOM   6961 H HG23 . THR A 1 459 ? 134.829 112.280 107.127 1.00 59.60  ? 459 THR A HG23 1 
ATOM   6962 N N    . PHE A 1 460 ? 132.946 114.105 106.585 1.00 60.14  ? 460 PHE A N    1 
ATOM   6963 C CA   . PHE A 1 460 ? 132.928 115.137 107.616 1.00 60.14  ? 460 PHE A CA   1 
ATOM   6964 C C    . PHE A 1 460 ? 131.665 115.988 107.574 1.00 60.14  ? 460 PHE A C    1 
ATOM   6965 O O    . PHE A 1 460 ? 131.358 116.655 108.566 1.00 60.14  ? 460 PHE A O    1 
ATOM   6966 C CB   . PHE A 1 460 ? 134.178 116.016 107.506 1.00 60.14  ? 460 PHE A CB   1 
ATOM   6967 C CG   . PHE A 1 460 ? 134.080 117.104 106.477 1.00 60.14  ? 460 PHE A CG   1 
ATOM   6968 C CD1  . PHE A 1 460 ? 134.144 116.813 105.127 1.00 60.14  ? 460 PHE A CD1  1 
ATOM   6969 C CD2  . PHE A 1 460 ? 133.960 118.426 106.866 1.00 60.14  ? 460 PHE A CD2  1 
ATOM   6970 C CE1  . PHE A 1 460 ? 134.067 117.820 104.184 1.00 60.14  ? 460 PHE A CE1  1 
ATOM   6971 C CE2  . PHE A 1 460 ? 133.883 119.434 105.928 1.00 60.14  ? 460 PHE A CE2  1 
ATOM   6972 C CZ   . PHE A 1 460 ? 133.936 119.131 104.586 1.00 60.14  ? 460 PHE A CZ   1 
ATOM   6973 H H    . PHE A 1 460 ? 133.460 114.270 105.915 1.00 60.14  ? 460 PHE A H    1 
ATOM   6974 H HA   . PHE A 1 460 ? 132.956 114.703 108.483 1.00 60.14  ? 460 PHE A HA   1 
ATOM   6975 H HB2  . PHE A 1 460 ? 134.339 116.437 108.365 1.00 60.14  ? 460 PHE A HB2  1 
ATOM   6976 H HB3  . PHE A 1 460 ? 134.933 115.455 107.270 1.00 60.14  ? 460 PHE A HB3  1 
ATOM   6977 H HD1  . PHE A 1 460 ? 134.230 115.929 104.850 1.00 60.14  ? 460 PHE A HD1  1 
ATOM   6978 H HD2  . PHE A 1 460 ? 133.922 118.637 107.771 1.00 60.14  ? 460 PHE A HD2  1 
ATOM   6979 H HE1  . PHE A 1 460 ? 134.104 117.613 103.278 1.00 60.14  ? 460 PHE A HE1  1 
ATOM   6980 H HE2  . PHE A 1 460 ? 133.795 120.319 106.201 1.00 60.14  ? 460 PHE A HE2  1 
ATOM   6981 H HZ   . PHE A 1 460 ? 133.884 119.810 103.953 1.00 60.14  ? 460 PHE A HZ   1 
ATOM   6982 N N    . ILE A 1 461 ? 130.926 115.984 106.465 1.00 56.63  ? 461 ILE A N    1 
ATOM   6983 C CA   . ILE A 1 461 ? 129.630 116.647 106.394 1.00 56.63  ? 461 ILE A CA   1 
ATOM   6984 C C    . ILE A 1 461 ? 128.542 115.697 105.897 1.00 56.63  ? 461 ILE A C    1 
ATOM   6985 O O    . ILE A 1 461 ? 127.542 116.139 105.349 1.00 56.63  ? 461 ILE A O    1 
ATOM   6986 C CB   . ILE A 1 461 ? 129.689 117.913 105.516 1.00 56.63  ? 461 ILE A CB   1 
ATOM   6987 C CG1  . ILE A 1 461 ? 130.173 117.572 104.106 1.00 56.63  ? 461 ILE A CG1  1 
ATOM   6988 C CG2  . ILE A 1 461 ? 130.582 118.960 106.155 1.00 56.63  ? 461 ILE A CG2  1 
ATOM   6989 C CD1  . ILE A 1 461 ? 129.908 118.664 103.089 1.00 56.63  ? 461 ILE A CD1  1 
ATOM   6990 H H    . ILE A 1 461 ? 131.159 115.599 105.732 1.00 56.63  ? 461 ILE A H    1 
ATOM   6991 H HA   . ILE A 1 461 ? 129.379 116.932 107.285 1.00 56.63  ? 461 ILE A HA   1 
ATOM   6992 H HB   . ILE A 1 461 ? 128.793 118.279 105.449 1.00 56.63  ? 461 ILE A HB   1 
ATOM   6993 H HG12 . ILE A 1 461 ? 131.130 117.421 104.134 1.00 56.63  ? 461 ILE A HG12 1 
ATOM   6994 H HG13 . ILE A 1 461 ? 129.723 116.771 103.799 1.00 56.63  ? 461 ILE A HG13 1 
ATOM   6995 H HG21 . ILE A 1 461 ? 131.033 119.463 105.460 1.00 56.63  ? 461 ILE A HG21 1 
ATOM   6996 H HG22 . ILE A 1 461 ? 130.033 119.555 106.690 1.00 56.63  ? 461 ILE A HG22 1 
ATOM   6997 H HG23 . ILE A 1 461 ? 131.235 118.519 106.718 1.00 56.63  ? 461 ILE A HG23 1 
ATOM   6998 H HD11 . ILE A 1 461 ? 130.221 118.365 102.220 1.00 56.63  ? 461 ILE A HD11 1 
ATOM   6999 H HD12 . ILE A 1 461 ? 128.954 118.838 103.053 1.00 56.63  ? 461 ILE A HD12 1 
ATOM   7000 H HD13 . ILE A 1 461 ? 130.382 119.468 103.351 1.00 56.63  ? 461 ILE A HD13 1 
ATOM   7001 N N    . ARG A 1 462 ? 128.724 114.388 106.086 1.00 54.65  ? 462 ARG A N    1 
ATOM   7002 C CA   . ARG A 1 462 ? 127.755 113.432 105.558 1.00 54.65  ? 462 ARG A CA   1 
ATOM   7003 C C    . ARG A 1 462 ? 126.375 113.662 106.156 1.00 54.65  ? 462 ARG A C    1 
ATOM   7004 O O    . ARG A 1 462 ? 125.366 113.607 105.445 1.00 54.65  ? 462 ARG A O    1 
ATOM   7005 C CB   . ARG A 1 462 ? 128.212 112.002 105.838 1.00 54.65  ? 462 ARG A CB   1 
ATOM   7006 C CG   . ARG A 1 462 ? 127.447 110.957 105.045 1.00 54.65  ? 462 ARG A CG   1 
ATOM   7007 C CD   . ARG A 1 462 ? 127.544 109.584 105.683 1.00 54.65  ? 462 ARG A CD   1 
ATOM   7008 N NE   . ARG A 1 462 ? 128.842 109.352 106.299 1.00 54.65  ? 462 ARG A NE   1 
ATOM   7009 C CZ   . ARG A 1 462 ? 129.976 109.212 105.629 1.00 54.65  ? 462 ARG A CZ   1 
ATOM   7010 N NH1  . ARG A 1 462 ? 130.020 109.319 104.312 1.00 54.65  ? 462 ARG A NH1  1 
ATOM   7011 N NH2  . ARG A 1 462 ? 131.098 108.966 106.298 1.00 54.65  ? 462 ARG A NH2  1 
ATOM   7012 H H    . ARG A 1 462 ? 129.386 114.036 106.508 1.00 54.65  ? 462 ARG A H    1 
ATOM   7013 H HA   . ARG A 1 462 ? 127.690 113.545 104.597 1.00 54.65  ? 462 ARG A HA   1 
ATOM   7014 H HB2  . ARG A 1 462 ? 129.151 111.919 105.612 1.00 54.65  ? 462 ARG A HB2  1 
ATOM   7015 H HB3  . ARG A 1 462 ? 128.082 111.813 106.781 1.00 54.65  ? 462 ARG A HB3  1 
ATOM   7016 H HG2  . ARG A 1 462 ? 126.510 111.205 105.007 1.00 54.65  ? 462 ARG A HG2  1 
ATOM   7017 H HG3  . ARG A 1 462 ? 127.814 110.903 104.149 1.00 54.65  ? 462 ARG A HG3  1 
ATOM   7018 H HD2  . ARG A 1 462 ? 126.865 109.505 106.371 1.00 54.65  ? 462 ARG A HD2  1 
ATOM   7019 H HD3  . ARG A 1 462 ? 127.410 108.903 105.007 1.00 54.65  ? 462 ARG A HD3  1 
ATOM   7020 H HE   . ARG A 1 462 ? 128.874 109.298 107.157 1.00 54.65  ? 462 ARG A HE   1 
ATOM   7021 H HH11 . ARG A 1 462 ? 129.302 109.477 103.866 1.00 54.65  ? 462 ARG A HH11 1 
ATOM   7022 H HH12 . ARG A 1 462 ? 130.769 109.227 103.900 1.00 54.65  ? 462 ARG A HH12 1 
ATOM   7023 H HH21 . ARG A 1 462 ? 131.081 108.897 107.156 1.00 54.65  ? 462 ARG A HH21 1 
ATOM   7024 H HH22 . ARG A 1 462 ? 131.841 108.877 105.875 1.00 54.65  ? 462 ARG A HH22 1 
ATOM   7025 N N    . ASN A 1 463 ? 126.310 113.913 107.463 1.00 51.39  ? 463 ASN A N    1 
ATOM   7026 C CA   . ASN A 1 463 ? 125.018 114.099 108.113 1.00 51.39  ? 463 ASN A CA   1 
ATOM   7027 C C    . ASN A 1 463 ? 124.304 115.330 107.570 1.00 51.39  ? 463 ASN A C    1 
ATOM   7028 O O    . ASN A 1 463 ? 123.094 115.296 107.309 1.00 51.39  ? 463 ASN A O    1 
ATOM   7029 C CB   . ASN A 1 463 ? 125.215 114.208 109.623 1.00 51.39  ? 463 ASN A CB   1 
ATOM   7030 C CG   . ASN A 1 463 ? 124.017 113.724 110.401 1.00 51.39  ? 463 ASN A CG   1 
ATOM   7031 O OD1  . ASN A 1 463 ? 122.909 113.658 109.875 1.00 51.39  ? 463 ASN A OD1  1 
ATOM   7032 N ND2  . ASN A 1 463 ? 124.232 113.382 111.664 1.00 51.39  ? 463 ASN A ND2  1 
ATOM   7033 H H    . ASN A 1 463 ? 126.989 113.979 107.987 1.00 51.39  ? 463 ASN A H    1 
ATOM   7034 H HA   . ASN A 1 463 ? 124.461 113.325 107.938 1.00 51.39  ? 463 ASN A HA   1 
ATOM   7035 H HB2  . ASN A 1 463 ? 125.974 113.663 109.879 1.00 51.39  ? 463 ASN A HB2  1 
ATOM   7036 H HB3  . ASN A 1 463 ? 125.374 115.136 109.858 1.00 51.39  ? 463 ASN A HB3  1 
ATOM   7037 H HD21 . ASN A 1 463 ? 123.581 113.100 112.150 1.00 51.39  ? 463 ASN A HD21 1 
ATOM   7038 H HD22 . ASN A 1 463 ? 125.022 113.443 111.997 1.00 51.39  ? 463 ASN A HD22 1 
ATOM   7039 N N    . LEU A 1 464 ? 125.041 116.425 107.378 1.00 51.89  ? 464 LEU A N    1 
ATOM   7040 C CA   . LEU A 1 464 ? 124.425 117.656 106.895 1.00 51.89  ? 464 LEU A CA   1 
ATOM   7041 C C    . LEU A 1 464 ? 123.804 117.457 105.519 1.00 51.89  ? 464 LEU A C    1 
ATOM   7042 O O    . LEU A 1 464 ? 122.718 117.978 105.237 1.00 51.89  ? 464 LEU A O    1 
ATOM   7043 C CB   . LEU A 1 464 ? 125.466 118.771 106.855 1.00 51.89  ? 464 LEU A CB   1 
ATOM   7044 C CG   . LEU A 1 464 ? 124.925 120.197 106.909 1.00 51.89  ? 464 LEU A CG   1 
ATOM   7045 C CD1  . LEU A 1 464 ? 124.259 120.459 108.247 1.00 51.89  ? 464 LEU A CD1  1 
ATOM   7046 C CD2  . LEU A 1 464 ? 126.042 121.191 106.664 1.00 51.89  ? 464 LEU A CD2  1 
ATOM   7047 H H    . LEU A 1 464 ? 125.887 116.480 107.519 1.00 51.89  ? 464 LEU A H    1 
ATOM   7048 H HA   . LEU A 1 464 ? 123.719 117.915 107.507 1.00 51.89  ? 464 LEU A HA   1 
ATOM   7049 H HB2  . LEU A 1 464 ? 126.064 118.659 107.610 1.00 51.89  ? 464 LEU A HB2  1 
ATOM   7050 H HB3  . LEU A 1 464 ? 125.969 118.686 106.030 1.00 51.89  ? 464 LEU A HB3  1 
ATOM   7051 H HG   . LEU A 1 464 ? 124.260 120.312 106.213 1.00 51.89  ? 464 LEU A HG   1 
ATOM   7052 H HD11 . LEU A 1 464 ? 124.100 121.412 108.337 1.00 51.89  ? 464 LEU A HD11 1 
ATOM   7053 H HD12 . LEU A 1 464 ? 123.417 119.980 108.283 1.00 51.89  ? 464 LEU A HD12 1 
ATOM   7054 H HD13 . LEU A 1 464 ? 124.846 120.154 108.956 1.00 51.89  ? 464 LEU A HD13 1 
ATOM   7055 H HD21 . LEU A 1 464 ? 125.687 122.090 106.747 1.00 51.89  ? 464 LEU A HD21 1 
ATOM   7056 H HD22 . LEU A 1 464 ? 126.741 121.048 107.321 1.00 51.89  ? 464 LEU A HD22 1 
ATOM   7057 H HD23 . LEU A 1 464 ? 126.395 121.054 105.770 1.00 51.89  ? 464 LEU A HD23 1 
ATOM   7058 N N    . GLY A 1 465 ? 124.484 116.714 104.646 1.00 52.03  ? 465 GLY A N    1 
ATOM   7059 C CA   . GLY A 1 465 ? 123.959 116.502 103.308 1.00 52.03  ? 465 GLY A CA   1 
ATOM   7060 C C    . GLY A 1 465 ? 122.647 115.745 103.312 1.00 52.03  ? 465 GLY A C    1 
ATOM   7061 O O    . GLY A 1 465 ? 121.690 116.129 102.633 1.00 52.03  ? 465 GLY A O    1 
ATOM   7062 H H    . GLY A 1 465 ? 125.238 116.331 104.804 1.00 52.03  ? 465 GLY A H    1 
ATOM   7063 H HA2  . GLY A 1 465 ? 123.819 117.359 102.876 1.00 52.03  ? 465 GLY A HA2  1 
ATOM   7064 H HA3  . GLY A 1 465 ? 124.603 115.998 102.787 1.00 52.03  ? 465 GLY A HA3  1 
ATOM   7065 N N    . VAL A 1 466 ? 122.582 114.653 104.077 1.00 49.91  ? 466 VAL A N    1 
ATOM   7066 C CA   . VAL A 1 466 ? 121.342 113.888 104.140 1.00 49.91  ? 466 VAL A CA   1 
ATOM   7067 C C    . VAL A 1 466 ? 120.240 114.717 104.781 1.00 49.91  ? 466 VAL A C    1 
ATOM   7068 O O    . VAL A 1 466 ? 119.083 114.660 104.357 1.00 49.91  ? 466 VAL A O    1 
ATOM   7069 C CB   . VAL A 1 466 ? 121.555 112.554 104.879 1.00 49.91  ? 466 VAL A CB   1 
ATOM   7070 C CG1  . VAL A 1 466 ? 122.413 111.624 104.047 1.00 49.91  ? 466 VAL A CG1  1 
ATOM   7071 C CG2  . VAL A 1 466 ? 122.180 112.778 106.240 1.00 49.91  ? 466 VAL A CG2  1 
ATOM   7072 H H    . VAL A 1 466 ? 123.228 114.343 104.550 1.00 49.91  ? 466 VAL A H    1 
ATOM   7073 H HA   . VAL A 1 466 ? 121.062 113.678 103.235 1.00 49.91  ? 466 VAL A HA   1 
ATOM   7074 H HB   . VAL A 1 466 ? 120.694 112.128 105.012 1.00 49.91  ? 466 VAL A HB   1 
ATOM   7075 H HG11 . VAL A 1 466 ? 122.579 110.813 104.554 1.00 49.91  ? 466 VAL A HG11 1 
ATOM   7076 H HG12 . VAL A 1 466 ? 121.941 111.410 103.227 1.00 49.91  ? 466 VAL A HG12 1 
ATOM   7077 H HG13 . VAL A 1 466 ? 123.253 112.064 103.843 1.00 49.91  ? 466 VAL A HG13 1 
ATOM   7078 H HG21 . VAL A 1 466 ? 122.209 111.930 106.711 1.00 49.91  ? 466 VAL A HG21 1 
ATOM   7079 H HG22 . VAL A 1 466 ? 123.079 113.120 106.128 1.00 49.91  ? 466 VAL A HG22 1 
ATOM   7080 H HG23 . VAL A 1 466 ? 121.640 113.410 106.739 1.00 49.91  ? 466 VAL A HG23 1 
ATOM   7081 N N    . MET A 1 467 ? 120.574 115.522 105.792 1.00 47.02  ? 467 MET A N    1 
ATOM   7082 C CA   . MET A 1 467 ? 119.562 116.385 106.398 1.00 47.02  ? 467 MET A CA   1 
ATOM   7083 C C    . MET A 1 467 ? 118.982 117.358 105.377 1.00 47.02  ? 467 MET A C    1 
ATOM   7084 O O    . MET A 1 467 ? 117.756 117.495 105.250 1.00 47.02  ? 467 MET A O    1 
ATOM   7085 C CB   . MET A 1 467 ? 120.168 117.154 107.568 1.00 47.02  ? 467 MET A CB   1 
ATOM   7086 C CG   . MET A 1 467 ? 120.500 116.301 108.759 1.00 47.02  ? 467 MET A CG   1 
ATOM   7087 S SD   . MET A 1 467 ? 119.047 115.541 109.477 1.00 47.02  ? 467 MET A SD   1 
ATOM   7088 C CE   . MET A 1 467 ? 119.839 114.510 110.692 1.00 47.02  ? 467 MET A CE   1 
ATOM   7089 H H    . MET A 1 467 ? 121.358 115.585 106.138 1.00 47.02  ? 467 MET A H    1 
ATOM   7090 H HA   . MET A 1 467 ? 118.844 115.831 106.740 1.00 47.02  ? 467 MET A HA   1 
ATOM   7091 H HB2  . MET A 1 467 ? 120.989 117.576 107.270 1.00 47.02  ? 467 MET A HB2  1 
ATOM   7092 H HB3  . MET A 1 467 ? 119.537 117.831 107.852 1.00 47.02  ? 467 MET A HB3  1 
ATOM   7093 H HG2  . MET A 1 467 ? 121.102 115.592 108.488 1.00 47.02  ? 467 MET A HG2  1 
ATOM   7094 H HG3  . MET A 1 467 ? 120.919 116.852 109.439 1.00 47.02  ? 467 MET A HG3  1 
ATOM   7095 H HE1  . MET A 1 467 ? 119.179 113.908 111.063 1.00 47.02  ? 467 MET A HE1  1 
ATOM   7096 H HE2  . MET A 1 467 ? 120.544 114.004 110.259 1.00 47.02  ? 467 MET A HE2  1 
ATOM   7097 H HE3  . MET A 1 467 ? 120.216 115.068 111.389 1.00 47.02  ? 467 MET A HE3  1 
ATOM   7098 N N    . VAL A 1 468 ? 119.853 118.058 104.650 1.00 49.27  ? 468 VAL A N    1 
ATOM   7099 C CA   . VAL A 1 468 ? 119.382 119.055 103.694 1.00 49.27  ? 468 VAL A CA   1 
ATOM   7100 C C    . VAL A 1 468 ? 118.557 118.390 102.601 1.00 49.27  ? 468 VAL A C    1 
ATOM   7101 O O    . VAL A 1 468 ? 117.465 118.855 102.255 1.00 49.27  ? 468 VAL A O    1 
ATOM   7102 C CB   . VAL A 1 468 ? 120.567 119.839 103.107 1.00 49.27  ? 468 VAL A CB   1 
ATOM   7103 C CG1  . VAL A 1 468 ? 120.107 120.691 101.937 1.00 49.27  ? 468 VAL A CG1  1 
ATOM   7104 C CG2  . VAL A 1 468 ? 121.206 120.702 104.176 1.00 49.27  ? 468 VAL A CG2  1 
ATOM   7105 H H    . VAL A 1 468 ? 120.708 117.976 104.692 1.00 49.27  ? 468 VAL A H    1 
ATOM   7106 H HA   . VAL A 1 468 ? 118.807 119.686 104.156 1.00 49.27  ? 468 VAL A HA   1 
ATOM   7107 H HB   . VAL A 1 468 ? 121.233 119.214 102.783 1.00 49.27  ? 468 VAL A HB   1 
ATOM   7108 H HG11 . VAL A 1 468 ? 120.782 121.363 101.754 1.00 49.27  ? 468 VAL A HG11 1 
ATOM   7109 H HG12 . VAL A 1 468 ? 119.988 120.124 101.159 1.00 49.27  ? 468 VAL A HG12 1 
ATOM   7110 H HG13 . VAL A 1 468 ? 119.269 121.119 102.170 1.00 49.27  ? 468 VAL A HG13 1 
ATOM   7111 H HG21 . VAL A 1 468 ? 121.996 121.127 103.806 1.00 49.27  ? 468 VAL A HG21 1 
ATOM   7112 H HG22 . VAL A 1 468 ? 120.570 121.377 104.459 1.00 49.27  ? 468 VAL A HG22 1 
ATOM   7113 H HG23 . VAL A 1 468 ? 121.453 120.142 104.928 1.00 49.27  ? 468 VAL A HG23 1 
ATOM   7114 N N    . CYS A 1 469 ? 119.059 117.286 102.046 1.00 51.38  ? 469 CYS A N    1 
ATOM   7115 C CA   . CYS A 1 469 ? 118.323 116.609 100.987 1.00 51.38  ? 469 CYS A CA   1 
ATOM   7116 C C    . CYS A 1 469 ? 117.049 115.954 101.499 1.00 51.38  ? 469 CYS A C    1 
ATOM   7117 O O    . CYS A 1 469 ? 116.171 115.631 100.694 1.00 51.38  ? 469 CYS A O    1 
ATOM   7118 C CB   . CYS A 1 469 ? 119.209 115.566 100.314 1.00 51.38  ? 469 CYS A CB   1 
ATOM   7119 S SG   . CYS A 1 469 ? 120.672 116.257 99.520  1.00 51.38  ? 469 CYS A SG   1 
ATOM   7120 H H    . CYS A 1 469 ? 119.805 116.917 102.261 1.00 51.38  ? 469 CYS A H    1 
ATOM   7121 H HA   . CYS A 1 469 ? 118.071 117.262 100.316 1.00 51.38  ? 469 CYS A HA   1 
ATOM   7122 H HB2  . CYS A 1 469 ? 119.506 114.930 100.984 1.00 51.38  ? 469 CYS A HB2  1 
ATOM   7123 H HB3  . CYS A 1 469 ? 118.692 115.109 99.633  1.00 51.38  ? 469 CYS A HB3  1 
ATOM   7124 H HG   . CYS A 1 469 ? 121.343 116.811 100.346 1.00 51.38  ? 469 CYS A HG   1 
ATOM   7125 N N    . SER A 1 470 ? 116.929 115.740 102.809 1.00 49.95  ? 470 SER A N    1 
ATOM   7126 C CA   . SER A 1 470 ? 115.711 115.187 103.376 1.00 49.95  ? 470 SER A CA   1 
ATOM   7127 C C    . SER A 1 470 ? 114.668 116.248 103.677 1.00 49.95  ? 470 SER A C    1 
ATOM   7128 O O    . SER A 1 470 ? 113.472 115.937 103.678 1.00 49.95  ? 470 SER A O    1 
ATOM   7129 C CB   . SER A 1 470 ? 116.031 114.427 104.666 1.00 49.95  ? 470 SER A CB   1 
ATOM   7130 O OG   . SER A 1 470 ? 114.891 113.742 105.150 1.00 49.95  ? 470 SER A OG   1 
ATOM   7131 H H    . SER A 1 470 ? 117.543 115.907 103.388 1.00 49.95  ? 470 SER A H    1 
ATOM   7132 H HA   . SER A 1 470 ? 115.327 114.558 102.746 1.00 49.95  ? 470 SER A HA   1 
ATOM   7133 H HB2  . SER A 1 470 ? 116.735 113.784 104.488 1.00 49.95  ? 470 SER A HB2  1 
ATOM   7134 H HB3  . SER A 1 470 ? 116.324 115.062 105.338 1.00 49.95  ? 470 SER A HB3  1 
ATOM   7135 H HG   . SER A 1 470 ? 114.251 114.277 105.248 1.00 49.95  ? 470 SER A HG   1 
ATOM   7136 N N    . SER A 1 471 ? 115.089 117.487 103.934 1.00 49.48  ? 471 SER A N    1 
ATOM   7137 C CA   . SER A 1 471 ? 114.116 118.540 104.216 1.00 49.48  ? 471 SER A CA   1 
ATOM   7138 C C    . SER A 1 471 ? 113.058 118.622 103.120 1.00 49.48  ? 471 SER A C    1 
ATOM   7139 O O    . SER A 1 471 ? 111.871 118.844 103.400 1.00 49.48  ? 471 SER A O    1 
ATOM   7140 C CB   . SER A 1 471 ? 114.824 119.884 104.370 1.00 49.48  ? 471 SER A CB   1 
ATOM   7141 O OG   . SER A 1 471 ? 115.373 120.309 103.137 1.00 49.48  ? 471 SER A OG   1 
ATOM   7142 H H    . SER A 1 471 ? 115.911 117.738 103.952 1.00 49.48  ? 471 SER A H    1 
ATOM   7143 H HA   . SER A 1 471 ? 113.666 118.339 105.052 1.00 49.48  ? 471 SER A HA   1 
ATOM   7144 H HB2  . SER A 1 471 ? 114.183 120.546 104.673 1.00 49.48  ? 471 SER A HB2  1 
ATOM   7145 H HB3  . SER A 1 471 ? 115.539 119.792 105.020 1.00 49.48  ? 471 SER A HB3  1 
ATOM   7146 H HG   . SER A 1 471 ? 115.943 119.753 102.870 1.00 49.48  ? 471 SER A HG   1 
ATOM   7147 N N    . LEU A 1 472 ? 113.468 118.447 101.863 1.00 53.08  ? 472 LEU A N    1 
ATOM   7148 C CA   . LEU A 1 472 ? 112.512 118.537 100.767 1.00 53.08  ? 472 LEU A CA   1 
ATOM   7149 C C    . LEU A 1 472 ? 111.465 117.435 100.839 1.00 53.08  ? 472 LEU A C    1 
ATOM   7150 O O    . LEU A 1 472 ? 110.351 117.614 100.341 1.00 53.08  ? 472 LEU A O    1 
ATOM   7151 C CB   . LEU A 1 472 ? 113.237 118.491 99.426  1.00 53.08  ? 472 LEU A CB   1 
ATOM   7152 C CG   . LEU A 1 472 ? 113.646 119.862 98.890  1.00 53.08  ? 472 LEU A CG   1 
ATOM   7153 C CD1  . LEU A 1 472 ? 114.749 120.470 99.736  1.00 53.08  ? 472 LEU A CD1  1 
ATOM   7154 C CD2  . LEU A 1 472 ? 114.072 119.752 97.440  1.00 53.08  ? 472 LEU A CD2  1 
ATOM   7155 H H    . LEU A 1 472 ? 114.277 118.278 101.626 1.00 53.08  ? 472 LEU A H    1 
ATOM   7156 H HA   . LEU A 1 472 ? 112.051 119.388 100.826 1.00 53.08  ? 472 LEU A HA   1 
ATOM   7157 H HB2  . LEU A 1 472 ? 114.043 117.960 99.523  1.00 53.08  ? 472 LEU A HB2  1 
ATOM   7158 H HB3  . LEU A 1 472 ? 112.652 118.081 98.770  1.00 53.08  ? 472 LEU A HB3  1 
ATOM   7159 H HG   . LEU A 1 472 ? 112.880 120.455 98.930  1.00 53.08  ? 472 LEU A HG   1 
ATOM   7160 H HD11 . LEU A 1 472 ? 114.978 121.341 99.375  1.00 53.08  ? 472 LEU A HD11 1 
ATOM   7161 H HD12 . LEU A 1 472 ? 114.433 120.564 100.648 1.00 53.08  ? 472 LEU A HD12 1 
ATOM   7162 H HD13 . LEU A 1 472 ? 115.523 119.887 99.711  1.00 53.08  ? 472 LEU A HD13 1 
ATOM   7163 H HD21 . LEU A 1 472 ? 114.527 120.568 97.179  1.00 53.08  ? 472 LEU A HD21 1 
ATOM   7164 H HD22 . LEU A 1 472 ? 114.667 118.994 97.347  1.00 53.08  ? 472 LEU A HD22 1 
ATOM   7165 H HD23 . LEU A 1 472 ? 113.283 119.621 96.890  1.00 53.08  ? 472 LEU A HD23 1 
ATOM   7166 N N    . CYS A 1 473 ? 111.790 116.294 101.447 1.00 53.65  ? 473 CYS A N    1 
ATOM   7167 C CA   . CYS A 1 473 ? 110.780 115.257 101.628 1.00 53.65  ? 473 CYS A CA   1 
ATOM   7168 C C    . CYS A 1 473 ? 109.600 115.792 102.429 1.00 53.65  ? 473 CYS A C    1 
ATOM   7169 O O    . CYS A 1 473 ? 108.442 115.694 102.003 1.00 53.65  ? 473 CYS A O    1 
ATOM   7170 C CB   . CYS A 1 473 ? 111.394 114.043 102.323 1.00 53.65  ? 473 CYS A CB   1 
ATOM   7171 S SG   . CYS A 1 473 ? 110.237 112.693 102.638 1.00 53.65  ? 473 CYS A SG   1 
ATOM   7172 H H    . CYS A 1 473 ? 112.570 116.101 101.755 1.00 53.65  ? 473 CYS A H    1 
ATOM   7173 H HA   . CYS A 1 473 ? 110.453 114.975 100.760 1.00 53.65  ? 473 CYS A HA   1 
ATOM   7174 H HB2  . CYS A 1 473 ? 112.109 113.696 101.767 1.00 53.65  ? 473 CYS A HB2  1 
ATOM   7175 H HB3  . CYS A 1 473 ? 111.753 114.324 103.179 1.00 53.65  ? 473 CYS A HB3  1 
ATOM   7176 H HG   . CYS A 1 473 ? 109.925 112.166 101.607 1.00 53.65  ? 473 CYS A HG   1 
ATOM   7177 N N    . ASP A 1 474 ? 109.881 116.386 103.590 1.00 52.87  ? 474 ASP A N    1 
ATOM   7178 C CA   . ASP A 1 474 ? 108.813 116.949 104.405 1.00 52.87  ? 474 ASP A CA   1 
ATOM   7179 C C    . ASP A 1 474 ? 108.155 118.137 103.720 1.00 52.87  ? 474 ASP A C    1 
ATOM   7180 O O    . ASP A 1 474 ? 106.944 118.335 103.860 1.00 52.87  ? 474 ASP A O    1 
ATOM   7181 C CB   . ASP A 1 474 ? 109.357 117.359 105.770 1.00 52.87  ? 474 ASP A CB   1 
ATOM   7182 C CG   . ASP A 1 474 ? 109.857 116.178 106.572 1.00 52.87  ? 474 ASP A CG   1 
ATOM   7183 O OD1  . ASP A 1 474 ? 109.256 115.090 106.460 1.00 52.87  ? 474 ASP A OD1  1 
ATOM   7184 O OD2  . ASP A 1 474 ? 110.851 116.335 107.310 1.00 52.87  ? 474 ASP A OD2  1 
ATOM   7185 H H    . ASP A 1 474 ? 110.671 116.473 103.921 1.00 52.87  ? 474 ASP A H    1 
ATOM   7186 H HA   . ASP A 1 474 ? 108.134 116.271 104.544 1.00 52.87  ? 474 ASP A HA   1 
ATOM   7187 H HB2  . ASP A 1 474 ? 110.097 117.973 105.646 1.00 52.87  ? 474 ASP A HB2  1 
ATOM   7188 H HB3  . ASP A 1 474 ? 108.650 117.788 106.277 1.00 52.87  ? 474 ASP A HB3  1 
ATOM   7189 N N    . LEU A 1 475 ? 108.925 118.939 102.982 1.00 55.23  ? 475 LEU A N    1 
ATOM   7190 C CA   . LEU A 1 475 ? 108.321 120.054 102.257 1.00 55.23  ? 475 LEU A CA   1 
ATOM   7191 C C    . LEU A 1 475 ? 107.282 119.554 101.260 1.00 55.23  ? 475 LEU A C    1 
ATOM   7192 O O    . LEU A 1 475 ? 106.167 120.086 101.181 1.00 55.23  ? 475 LEU A O    1 
ATOM   7193 C CB   . LEU A 1 475 ? 109.400 120.865 101.544 1.00 55.23  ? 475 LEU A CB   1 
ATOM   7194 C CG   . LEU A 1 475 ? 108.895 122.057 100.732 1.00 55.23  ? 475 LEU A CG   1 
ATOM   7195 C CD1  . LEU A 1 475 ? 108.175 123.046 101.629 1.00 55.23  ? 475 LEU A CD1  1 
ATOM   7196 C CD2  . LEU A 1 475 ? 110.049 122.727 100.012 1.00 55.23  ? 475 LEU A CD2  1 
ATOM   7197 H H    . LEU A 1 475 ? 109.776 118.860 102.885 1.00 55.23  ? 475 LEU A H    1 
ATOM   7198 H HA   . LEU A 1 475 ? 107.873 120.635 102.892 1.00 55.23  ? 475 LEU A HA   1 
ATOM   7199 H HB2  . LEU A 1 475 ? 110.018 121.205 102.209 1.00 55.23  ? 475 LEU A HB2  1 
ATOM   7200 H HB3  . LEU A 1 475 ? 109.871 120.277 100.934 1.00 55.23  ? 475 LEU A HB3  1 
ATOM   7201 H HG   . LEU A 1 475 ? 108.267 121.746 100.062 1.00 55.23  ? 475 LEU A HG   1 
ATOM   7202 H HD11 . LEU A 1 475 ? 107.988 123.852 101.123 1.00 55.23  ? 475 LEU A HD11 1 
ATOM   7203 H HD12 . LEU A 1 475 ? 107.345 122.649 101.937 1.00 55.23  ? 475 LEU A HD12 1 
ATOM   7204 H HD13 . LEU A 1 475 ? 108.744 123.256 102.386 1.00 55.23  ? 475 LEU A HD13 1 
ATOM   7205 H HD21 . LEU A 1 475 ? 109.713 123.495 99.523  1.00 55.23  ? 475 LEU A HD21 1 
ATOM   7206 H HD22 . LEU A 1 475 ? 110.705 123.013 100.666 1.00 55.23  ? 475 LEU A HD22 1 
ATOM   7207 H HD23 . LEU A 1 475 ? 110.448 122.092 99.397  1.00 55.23  ? 475 LEU A HD23 1 
ATOM   7208 N N    . GLY A 1 476 ? 107.634 118.529 100.485 1.00 59.05  ? 476 GLY A N    1 
ATOM   7209 C CA   . GLY A 1 476 ? 106.682 117.963 99.546  1.00 59.05  ? 476 GLY A CA   1 
ATOM   7210 C C    . GLY A 1 476 ? 105.488 117.345 100.244 1.00 59.05  ? 476 GLY A C    1 
ATOM   7211 O O    . GLY A 1 476 ? 104.350 117.482 99.788  1.00 59.05  ? 476 GLY A O    1 
ATOM   7212 H H    . GLY A 1 476 ? 108.407 118.152 100.485 1.00 59.05  ? 476 GLY A H    1 
ATOM   7213 H HA2  . GLY A 1 476 ? 106.365 118.659 98.950  1.00 59.05  ? 476 GLY A HA2  1 
ATOM   7214 H HA3  . GLY A 1 476 ? 107.118 117.278 99.016  1.00 59.05  ? 476 GLY A HA3  1 
ATOM   7215 N N    . GLY A 1 477 ? 105.729 116.654 101.359 1.00 59.09  ? 477 GLY A N    1 
ATOM   7216 C CA   . GLY A 1 477 ? 104.618 116.104 102.117 1.00 59.09  ? 477 GLY A CA   1 
ATOM   7217 C C    . GLY A 1 477 ? 103.654 117.178 102.583 1.00 59.09  ? 477 GLY A C    1 
ATOM   7218 O O    . GLY A 1 477 ? 102.438 116.978 102.585 1.00 59.09  ? 477 GLY A O    1 
ATOM   7219 H H    . GLY A 1 477 ? 106.508 116.495 101.687 1.00 59.09  ? 477 GLY A H    1 
ATOM   7220 H HA2  . GLY A 1 477 ? 104.131 115.473 101.564 1.00 59.09  ? 477 GLY A HA2  1 
ATOM   7221 H HA3  . GLY A 1 477 ? 104.957 115.634 102.895 1.00 59.09  ? 477 GLY A HA3  1 
ATOM   7222 N N    . ILE A 1 478 ? 104.186 118.333 102.983 1.00 56.77  ? 478 ILE A N    1 
ATOM   7223 C CA   . ILE A 1 478 ? 103.334 119.439 103.408 1.00 56.77  ? 478 ILE A CA   1 
ATOM   7224 C C    . ILE A 1 478 ? 102.553 119.997 102.227 1.00 56.77  ? 478 ILE A C    1 
ATOM   7225 O O    . ILE A 1 478 ? 101.354 120.274 102.331 1.00 56.77  ? 478 ILE A O    1 
ATOM   7226 C CB   . ILE A 1 478 ? 104.175 120.538 104.081 1.00 56.77  ? 478 ILE A CB   1 
ATOM   7227 C CG1  . ILE A 1 478 ? 104.615 120.097 105.477 1.00 56.77  ? 478 ILE A CG1  1 
ATOM   7228 C CG2  . ILE A 1 478 ? 103.387 121.843 104.139 1.00 56.77  ? 478 ILE A CG2  1 
ATOM   7229 C CD1  . ILE A 1 478 ? 105.541 121.083 106.170 1.00 56.77  ? 478 ILE A CD1  1 
ATOM   7230 H H    . ILE A 1 478 ? 105.029 118.499 103.017 1.00 56.77  ? 478 ILE A H    1 
ATOM   7231 H HA   . ILE A 1 478 ? 102.695 119.110 104.060 1.00 56.77  ? 478 ILE A HA   1 
ATOM   7232 H HB   . ILE A 1 478 ? 104.969 120.685 103.544 1.00 56.77  ? 478 ILE A HB   1 
ATOM   7233 H HG12 . ILE A 1 478 ? 103.827 119.991 106.033 1.00 56.77  ? 478 ILE A HG12 1 
ATOM   7234 H HG13 . ILE A 1 478 ? 105.083 119.251 105.405 1.00 56.77  ? 478 ILE A HG13 1 
ATOM   7235 H HG21 . ILE A 1 478 ? 103.801 122.443 104.778 1.00 56.77  ? 478 ILE A HG21 1 
ATOM   7236 H HG22 . ILE A 1 478 ? 103.389 122.256 103.261 1.00 56.77  ? 478 ILE A HG22 1 
ATOM   7237 H HG23 . ILE A 1 478 ? 102.477 121.651 104.414 1.00 56.77  ? 478 ILE A HG23 1 
ATOM   7238 H HD11 . ILE A 1 478 ? 106.056 120.617 106.846 1.00 56.77  ? 478 ILE A HD11 1 
ATOM   7239 H HD12 . ILE A 1 478 ? 106.138 121.469 105.510 1.00 56.77  ? 478 ILE A HD12 1 
ATOM   7240 H HD13 . ILE A 1 478 ? 105.008 121.782 106.581 1.00 56.77  ? 478 ILE A HD13 1 
ATOM   7241 N N    . ILE A 1 479 ? 103.223 120.187 101.091 1.00 61.13  ? 479 ILE A N    1 
ATOM   7242 C CA   . ILE A 1 479 ? 102.616 120.975 100.022 1.00 61.13  ? 479 ILE A CA   1 
ATOM   7243 C C    . ILE A 1 479 ? 101.650 120.153 99.175  1.00 61.13  ? 479 ILE A C    1 
ATOM   7244 O O    . ILE A 1 479 ? 100.686 120.703 98.631  1.00 61.13  ? 479 ILE A O    1 
ATOM   7245 C CB   . ILE A 1 479 ? 103.706 121.606 99.143  1.00 61.13  ? 479 ILE A CB   1 
ATOM   7246 C CG1  . ILE A 1 479 ? 103.121 122.758 98.327  1.00 61.13  ? 479 ILE A CG1  1 
ATOM   7247 C CG2  . ILE A 1 479 ? 104.301 120.567 98.211  1.00 61.13  ? 479 ILE A CG2  1 
ATOM   7248 C CD1  . ILE A 1 479 ? 104.143 123.501 97.498  1.00 61.13  ? 479 ILE A CD1  1 
ATOM   7249 H H    . ILE A 1 479 ? 104.008 119.880 100.917 1.00 61.13  ? 479 ILE A H    1 
ATOM   7250 H HA   . ILE A 1 479 ? 102.110 121.698 100.423 1.00 61.13  ? 479 ILE A HA   1 
ATOM   7251 H HB   . ILE A 1 479 ? 104.409 121.952 99.715  1.00 61.13  ? 479 ILE A HB   1 
ATOM   7252 H HG12 . ILE A 1 479 ? 102.450 122.404 97.722  1.00 61.13  ? 479 ILE A HG12 1 
ATOM   7253 H HG13 . ILE A 1 479 ? 102.712 123.395 98.934  1.00 61.13  ? 479 ILE A HG13 1 
ATOM   7254 H HG21 . ILE A 1 479 ? 105.163 120.881 97.896  1.00 61.13  ? 479 ILE A HG21 1 
ATOM   7255 H HG22 . ILE A 1 479 ? 104.410 119.735 98.698  1.00 61.13  ? 479 ILE A HG22 1 
ATOM   7256 H HG23 . ILE A 1 479 ? 103.703 120.433 97.460  1.00 61.13  ? 479 ILE A HG23 1 
ATOM   7257 H HD11 . ILE A 1 479 ? 103.711 124.255 97.068  1.00 61.13  ? 479 ILE A HD11 1 
ATOM   7258 H HD12 . ILE A 1 479 ? 104.854 123.813 98.079  1.00 61.13  ? 479 ILE A HD12 1 
ATOM   7259 H HD13 . ILE A 1 479 ? 104.504 122.900 96.827  1.00 61.13  ? 479 ILE A HD13 1 
ATOM   7260 N N    . THR A 1 480 ? 101.871 118.846 99.039  1.00 65.66  ? 480 THR A N    1 
ATOM   7261 C CA   . THR A 1 480 ? 101.108 118.078 98.056  1.00 65.66  ? 480 THR A CA   1 
ATOM   7262 C C    . THR A 1 480 ? 99.593  118.150 98.232  1.00 65.66  ? 480 THR A C    1 
ATOM   7263 O O    . THR A 1 480 ? 98.890  118.195 97.206  1.00 65.66  ? 480 THR A O    1 
ATOM   7264 C CB   . THR A 1 480 ? 101.574 116.614 98.049  1.00 65.66  ? 480 THR A CB   1 
ATOM   7265 O OG1  . THR A 1 480 ? 100.710 115.843 97.204  1.00 65.66  ? 480 THR A OG1  1 
ATOM   7266 C CG2  . THR A 1 480 ? 101.574 116.012 99.439  1.00 65.66  ? 480 THR A CG2  1 
ATOM   7267 H H    . THR A 1 480 ? 102.450 118.397 99.486  1.00 65.66  ? 480 THR A H    1 
ATOM   7268 H HA   . THR A 1 480 ? 101.305 118.441 97.178  1.00 65.66  ? 480 THR A HA   1 
ATOM   7269 H HB   . THR A 1 480 ? 102.478 116.570 97.702  1.00 65.66  ? 480 THR A HB   1 
ATOM   7270 H HG1  . THR A 1 480 ? 100.952 115.038 97.203  1.00 65.66  ? 480 THR A HG1  1 
ATOM   7271 H HG21 . THR A 1 480 ? 102.006 115.147 99.408  1.00 65.66  ? 480 THR A HG21 1 
ATOM   7272 H HG22 . THR A 1 480 ? 102.062 116.571 100.061 1.00 65.66  ? 480 THR A HG22 1 
ATOM   7273 H HG23 . THR A 1 480 ? 100.664 115.900 99.756  1.00 65.66  ? 480 THR A HG23 1 
ATOM   7274 N N    . PRO A 1 481 ? 99.021  118.134 99.442  1.00 66.52  ? 481 PRO A N    1 
ATOM   7275 C CA   . PRO A 1 481 ? 97.549  118.132 99.520  1.00 66.52  ? 481 PRO A CA   1 
ATOM   7276 C C    . PRO A 1 481 ? 96.921  119.341 98.852  1.00 66.52  ? 481 PRO A C    1 
ATOM   7277 O O    . PRO A 1 481 ? 95.934  119.205 98.115  1.00 66.52  ? 481 PRO A O    1 
ATOM   7278 C CB   . PRO A 1 481 ? 97.274  118.112 101.032 1.00 66.52  ? 481 PRO A CB   1 
ATOM   7279 C CG   . PRO A 1 481 ? 98.574  117.751 101.673 1.00 66.52  ? 481 PRO A CG   1 
ATOM   7280 C CD   . PRO A 1 481 ? 99.619  118.308 100.774 1.00 66.52  ? 481 PRO A CD   1 
ATOM   7281 H HA   . PRO A 1 481 ? 97.193  117.322 99.123  1.00 66.52  ? 481 PRO A HA   1 
ATOM   7282 H HB2  . PRO A 1 481 ? 96.982  118.990 101.321 1.00 66.52  ? 481 PRO A HB2  1 
ATOM   7283 H HB3  . PRO A 1 481 ? 96.599  117.444 101.230 1.00 66.52  ? 481 PRO A HB3  1 
ATOM   7284 H HG2  . PRO A 1 481 ? 98.627  118.154 102.554 1.00 66.52  ? 481 PRO A HG2  1 
ATOM   7285 H HG3  . PRO A 1 481 ? 98.652  116.786 101.732 1.00 66.52  ? 481 PRO A HG3  1 
ATOM   7286 H HD2  . PRO A 1 481 ? 99.746  119.251 100.957 1.00 66.52  ? 481 PRO A HD2  1 
ATOM   7287 H HD3  . PRO A 1 481 ? 100.443 117.814 100.868 1.00 66.52  ? 481 PRO A HD3  1 
ATOM   7288 N N    . PHE A 1 482 ? 97.483  120.528 99.082  1.00 67.55  ? 482 PHE A N    1 
ATOM   7289 C CA   . PHE A 1 482 ? 96.955  121.730 98.447  1.00 67.55  ? 482 PHE A CA   1 
ATOM   7290 C C    . PHE A 1 482 ? 97.077  121.643 96.934  1.00 67.55  ? 482 PHE A C    1 
ATOM   7291 O O    . PHE A 1 482 ? 96.157  122.032 96.205  1.00 67.55  ? 482 PHE A O    1 
ATOM   7292 C CB   . PHE A 1 482 ? 97.688  122.964 98.972  1.00 67.55  ? 482 PHE A CB   1 
ATOM   7293 C CG   . PHE A 1 482 ? 97.360  123.304 100.396 1.00 67.55  ? 482 PHE A CG   1 
ATOM   7294 C CD1  . PHE A 1 482 ? 97.809  122.509 101.436 1.00 67.55  ? 482 PHE A CD1  1 
ATOM   7295 C CD2  . PHE A 1 482 ? 96.610  124.427 100.695 1.00 67.55  ? 482 PHE A CD2  1 
ATOM   7296 C CE1  . PHE A 1 482 ? 97.509  122.823 102.745 1.00 67.55  ? 482 PHE A CE1  1 
ATOM   7297 C CE2  . PHE A 1 482 ? 96.308  124.746 102.003 1.00 67.55  ? 482 PHE A CE2  1 
ATOM   7298 C CZ   . PHE A 1 482 ? 96.758  123.943 103.029 1.00 67.55  ? 482 PHE A CZ   1 
ATOM   7299 H H    . PHE A 1 482 ? 98.161  120.660 99.593  1.00 67.55  ? 482 PHE A H    1 
ATOM   7300 H HA   . PHE A 1 482 ? 96.016  121.820 98.670  1.00 67.55  ? 482 PHE A HA   1 
ATOM   7301 H HB2  . PHE A 1 482 ? 98.644  122.807 98.917  1.00 67.55  ? 482 PHE A HB2  1 
ATOM   7302 H HB3  . PHE A 1 482 ? 97.448  123.726 98.423  1.00 67.55  ? 482 PHE A HB3  1 
ATOM   7303 H HD1  . PHE A 1 482 ? 98.315  121.752 101.249 1.00 67.55  ? 482 PHE A HD1  1 
ATOM   7304 H HD2  . PHE A 1 482 ? 96.303  124.972 100.007 1.00 67.55  ? 482 PHE A HD2  1 
ATOM   7305 H HE1  . PHE A 1 482 ? 97.814  122.280 103.436 1.00 67.55  ? 482 PHE A HE1  1 
ATOM   7306 H HE2  . PHE A 1 482 ? 95.801  125.502 102.192 1.00 67.55  ? 482 PHE A HE2  1 
ATOM   7307 H HZ   . PHE A 1 482 ? 96.556  124.157 103.911 1.00 67.55  ? 482 PHE A HZ   1 
ATOM   7308 N N    . LEU A 1 483 ? 98.210  121.144 96.441  1.00 69.77  ? 483 LEU A N    1 
ATOM   7309 C CA   . LEU A 1 483 ? 98.400  121.032 95.001  1.00 69.77  ? 483 LEU A CA   1 
ATOM   7310 C C    . LEU A 1 483 ? 97.353  120.113 94.387  1.00 69.77  ? 483 LEU A C    1 
ATOM   7311 O O    . LEU A 1 483 ? 96.743  120.444 93.363  1.00 69.77  ? 483 LEU A O    1 
ATOM   7312 C CB   . LEU A 1 483 ? 99.812  120.526 94.703  1.00 69.77  ? 483 LEU A CB   1 
ATOM   7313 C CG   . LEU A 1 483 ? 100.231 120.410 93.235  1.00 69.77  ? 483 LEU A CG   1 
ATOM   7314 C CD1  . LEU A 1 483 ? 101.741 120.538 93.114  1.00 69.77  ? 483 LEU A CD1  1 
ATOM   7315 C CD2  . LEU A 1 483 ? 99.769  119.097 92.616  1.00 69.77  ? 483 LEU A CD2  1 
ATOM   7316 H H    . LEU A 1 483 ? 98.874  120.868 96.914  1.00 69.77  ? 483 LEU A H    1 
ATOM   7317 H HA   . LEU A 1 483 ? 98.302  121.909 94.598  1.00 69.77  ? 483 LEU A HA   1 
ATOM   7318 H HB2  . LEU A 1 483 ? 100.440 121.130 95.130  1.00 69.77  ? 483 LEU A HB2  1 
ATOM   7319 H HB3  . LEU A 1 483 ? 99.903  119.644 95.097  1.00 69.77  ? 483 LEU A HB3  1 
ATOM   7320 H HG   . LEU A 1 483 ? 99.828  121.135 92.733  1.00 69.77  ? 483 LEU A HG   1 
ATOM   7321 H HD11 . LEU A 1 483 ? 101.992 120.450 92.181  1.00 69.77  ? 483 LEU A HD11 1 
ATOM   7322 H HD12 . LEU A 1 483 ? 102.013 121.407 93.449  1.00 69.77  ? 483 LEU A HD12 1 
ATOM   7323 H HD13 . LEU A 1 483 ? 102.160 119.835 93.636  1.00 69.77  ? 483 LEU A HD13 1 
ATOM   7324 H HD21 . LEU A 1 483 ? 100.270 118.941 91.801  1.00 69.77  ? 483 LEU A HD21 1 
ATOM   7325 H HD22 . LEU A 1 483 ? 99.931  118.376 93.244  1.00 69.77  ? 483 LEU A HD22 1 
ATOM   7326 H HD23 . LEU A 1 483 ? 98.823  119.153 92.414  1.00 69.77  ? 483 LEU A HD23 1 
ATOM   7327 N N    . VAL A 1 484 ? 97.122  118.953 95.004  1.00 73.24  ? 484 VAL A N    1 
ATOM   7328 C CA   . VAL A 1 484 ? 96.177  118.004 94.424  1.00 73.24  ? 484 VAL A CA   1 
ATOM   7329 C C    . VAL A 1 484 ? 94.755  118.547 94.505  1.00 73.24  ? 484 VAL A C    1 
ATOM   7330 O O    . VAL A 1 484 ? 93.952  118.346 93.587  1.00 73.24  ? 484 VAL A O    1 
ATOM   7331 C CB   . VAL A 1 484 ? 96.305  116.623 95.096  1.00 73.24  ? 484 VAL A CB   1 
ATOM   7332 C CG1  . VAL A 1 484 ? 95.989  116.700 96.578  1.00 73.24  ? 484 VAL A CG1  1 
ATOM   7333 C CG2  . VAL A 1 484 ? 95.403  115.611 94.403  1.00 73.24  ? 484 VAL A CG2  1 
ATOM   7334 H H    . VAL A 1 484 ? 97.489  118.699 95.738  1.00 73.24  ? 484 VAL A H    1 
ATOM   7335 H HA   . VAL A 1 484 ? 96.392  117.891 93.485  1.00 73.24  ? 484 VAL A HA   1 
ATOM   7336 H HB   . VAL A 1 484 ? 97.220  116.315 95.004  1.00 73.24  ? 484 VAL A HB   1 
ATOM   7337 H HG11 . VAL A 1 484 ? 96.028  115.805 96.952  1.00 73.24  ? 484 VAL A HG11 1 
ATOM   7338 H HG12 . VAL A 1 484 ? 96.648  117.263 97.006  1.00 73.24  ? 484 VAL A HG12 1 
ATOM   7339 H HG13 . VAL A 1 484 ? 95.100  117.067 96.704  1.00 73.24  ? 484 VAL A HG13 1 
ATOM   7340 H HG21 . VAL A 1 484 ? 95.595  114.727 94.752  1.00 73.24  ? 484 VAL A HG21 1 
ATOM   7341 H HG22 . VAL A 1 484 ? 94.476  115.840 94.576  1.00 73.24  ? 484 VAL A HG22 1 
ATOM   7342 H HG23 . VAL A 1 484 ? 95.577  115.635 93.449  1.00 73.24  ? 484 VAL A HG23 1 
ATOM   7343 N N    . PHE A 1 485 ? 94.414  119.242 95.595  1.00 75.90  ? 485 PHE A N    1 
ATOM   7344 C CA   . PHE A 1 485 ? 93.087  119.847 95.682  1.00 75.90  ? 485 PHE A CA   1 
ATOM   7345 C C    . PHE A 1 485 ? 92.894  120.901 94.599  1.00 75.90  ? 485 PHE A C    1 
ATOM   7346 O O    . PHE A 1 485 ? 91.870  120.916 93.908  1.00 75.90  ? 485 PHE A O    1 
ATOM   7347 C CB   . PHE A 1 485 ? 92.871  120.466 97.066  1.00 75.90  ? 485 PHE A CB   1 
ATOM   7348 C CG   . PHE A 1 485 ? 92.385  119.497 98.121  1.00 75.90  ? 485 PHE A CG   1 
ATOM   7349 C CD1  . PHE A 1 485 ? 91.804  118.280 97.787  1.00 75.90  ? 485 PHE A CD1  1 
ATOM   7350 C CD2  . PHE A 1 485 ? 92.496  119.826 99.462  1.00 75.90  ? 485 PHE A CD2  1 
ATOM   7351 C CE1  . PHE A 1 485 ? 91.361  117.415 98.766  1.00 75.90  ? 485 PHE A CE1  1 
ATOM   7352 C CE2  . PHE A 1 485 ? 92.053  118.964 100.445 1.00 75.90  ? 485 PHE A CE2  1 
ATOM   7353 C CZ   . PHE A 1 485 ? 91.485  117.758 100.096 1.00 75.90  ? 485 PHE A CZ   1 
ATOM   7354 H H    . PHE A 1 485 ? 94.919  119.374 96.278  1.00 75.90  ? 485 PHE A H    1 
ATOM   7355 H HA   . PHE A 1 485 ? 92.421  119.168 95.512  1.00 75.90  ? 485 PHE A HA   1 
ATOM   7356 H HB2  . PHE A 1 485 ? 93.713  120.836 97.374  1.00 75.90  ? 485 PHE A HB2  1 
ATOM   7357 H HB3  . PHE A 1 485 ? 92.212  121.173 96.990  1.00 75.90  ? 485 PHE A HB3  1 
ATOM   7358 H HD1  . PHE A 1 485 ? 91.715  118.036 96.896  1.00 75.90  ? 485 PHE A HD1  1 
ATOM   7359 H HD2  . PHE A 1 485 ? 92.879  120.639 99.704  1.00 75.90  ? 485 PHE A HD2  1 
ATOM   7360 H HE1  . PHE A 1 485 ? 90.978  116.602 98.529  1.00 75.90  ? 485 PHE A HE1  1 
ATOM   7361 H HE2  . PHE A 1 485 ? 92.138  119.197 101.341 1.00 75.90  ? 485 PHE A HE2  1 
ATOM   7362 H HZ   . PHE A 1 485 ? 91.186  117.176 100.757 1.00 75.90  ? 485 PHE A HZ   1 
ATOM   7363 N N    . ARG A 1 486 ? 93.870  121.796 94.438  1.00 76.71  ? 486 ARG A N    1 
ATOM   7364 C CA   . ARG A 1 486 ? 93.731  122.868 93.459  1.00 76.71  ? 486 ARG A CA   1 
ATOM   7365 C C    . ARG A 1 486 ? 93.646  122.314 92.042  1.00 76.71  ? 486 ARG A C    1 
ATOM   7366 O O    . ARG A 1 486 ? 92.771  122.706 91.262  1.00 76.71  ? 486 ARG A O    1 
ATOM   7367 C CB   . ARG A 1 486 ? 94.901  123.844 93.587  1.00 76.71  ? 486 ARG A CB   1 
ATOM   7368 C CG   . ARG A 1 486 ? 94.893  124.662 94.869  1.00 76.71  ? 486 ARG A CG   1 
ATOM   7369 C CD   . ARG A 1 486 ? 93.808  125.726 94.848  1.00 76.71  ? 486 ARG A CD   1 
ATOM   7370 N NE   . ARG A 1 486 ? 94.026  126.707 93.792  1.00 76.71  ? 486 ARG A NE   1 
ATOM   7371 C CZ   . ARG A 1 486 ? 94.793  127.782 93.909  1.00 76.71  ? 486 ARG A CZ   1 
ATOM   7372 N NH1  . ARG A 1 486 ? 95.441  128.052 95.031  1.00 76.71  ? 486 ARG A NH1  1 
ATOM   7373 N NH2  . ARG A 1 486 ? 94.915  128.608 92.874  1.00 76.71  ? 486 ARG A NH2  1 
ATOM   7374 H H    . ARG A 1 486 ? 94.610  121.803 94.876  1.00 76.71  ? 486 ARG A H    1 
ATOM   7375 H HA   . ARG A 1 486 ? 92.910  123.353 93.638  1.00 76.71  ? 486 ARG A HA   1 
ATOM   7376 H HB2  . ARG A 1 486 ? 95.729  123.340 93.565  1.00 76.71  ? 486 ARG A HB2  1 
ATOM   7377 H HB3  . ARG A 1 486 ? 94.874  124.462 92.839  1.00 76.71  ? 486 ARG A HB3  1 
ATOM   7378 H HG2  . ARG A 1 486 ? 94.726  124.074 95.622  1.00 76.71  ? 486 ARG A HG2  1 
ATOM   7379 H HG3  . ARG A 1 486 ? 95.750  125.104 94.972  1.00 76.71  ? 486 ARG A HG3  1 
ATOM   7380 H HD2  . ARG A 1 486 ? 92.949  125.304 94.693  1.00 76.71  ? 486 ARG A HD2  1 
ATOM   7381 H HD3  . ARG A 1 486 ? 93.798  126.190 95.700  1.00 76.71  ? 486 ARG A HD3  1 
ATOM   7382 H HE   . ARG A 1 486 ? 93.602  126.598 93.051  1.00 76.71  ? 486 ARG A HE   1 
ATOM   7383 H HH11 . ARG A 1 486 ? 95.373  127.528 95.708  1.00 76.71  ? 486 ARG A HH11 1 
ATOM   7384 H HH12 . ARG A 1 486 ? 95.933  128.756 95.082  1.00 76.71  ? 486 ARG A HH12 1 
ATOM   7385 H HH21 . ARG A 1 486 ? 94.499  128.442 92.140  1.00 76.71  ? 486 ARG A HH21 1 
ATOM   7386 H HH22 . ARG A 1 486 ? 95.410  129.308 92.938  1.00 76.71  ? 486 ARG A HH22 1 
ATOM   7387 N N    . LEU A 1 487 ? 94.544  121.391 91.692  1.00 76.62  ? 487 LEU A N    1 
ATOM   7388 C CA   . LEU A 1 487 ? 94.581  120.895 90.320  1.00 76.62  ? 487 LEU A CA   1 
ATOM   7389 C C    . LEU A 1 487 ? 93.300  120.153 89.963  1.00 76.62  ? 487 LEU A C    1 
ATOM   7390 O O    . LEU A 1 487 ? 92.814  120.248 88.830  1.00 76.62  ? 487 LEU A O    1 
ATOM   7391 C CB   . LEU A 1 487 ? 95.800  119.997 90.114  1.00 76.62  ? 487 LEU A CB   1 
ATOM   7392 C CG   . LEU A 1 487 ? 97.054  120.714 89.606  1.00 76.62  ? 487 LEU A CG   1 
ATOM   7393 C CD1  . LEU A 1 487 ? 97.565  121.727 90.620  1.00 76.62  ? 487 LEU A CD1  1 
ATOM   7394 C CD2  . LEU A 1 487 ? 98.141  119.709 89.261  1.00 76.62  ? 487 LEU A CD2  1 
ATOM   7395 H H    . LEU A 1 487 ? 95.128  121.043 92.219  1.00 76.62  ? 487 LEU A H    1 
ATOM   7396 H HA   . LEU A 1 487 ? 94.663  121.651 89.717  1.00 76.62  ? 487 LEU A HA   1 
ATOM   7397 H HB2  . LEU A 1 487 ? 96.024  119.580 90.960  1.00 76.62  ? 487 LEU A HB2  1 
ATOM   7398 H HB3  . LEU A 1 487 ? 95.572  119.312 89.465  1.00 76.62  ? 487 LEU A HB3  1 
ATOM   7399 H HG   . LEU A 1 487 ? 96.830  121.197 88.796  1.00 76.62  ? 487 LEU A HG   1 
ATOM   7400 H HD11 . LEU A 1 487 ? 98.299  122.223 90.225  1.00 76.62  ? 487 LEU A HD11 1 
ATOM   7401 H HD12 . LEU A 1 487 ? 96.846  122.333 90.856  1.00 76.62  ? 487 LEU A HD12 1 
ATOM   7402 H HD13 . LEU A 1 487 ? 97.873  121.255 91.409  1.00 76.62  ? 487 LEU A HD13 1 
ATOM   7403 H HD21 . LEU A 1 487 ? 98.883  120.178 88.848  1.00 76.62  ? 487 LEU A HD21 1 
ATOM   7404 H HD22 . LEU A 1 487 ? 98.436  119.271 90.074  1.00 76.62  ? 487 LEU A HD22 1 
ATOM   7405 H HD23 . LEU A 1 487 ? 97.781  119.053 88.645  1.00 76.62  ? 487 LEU A HD23 1 
ATOM   7406 N N    . MET A 1 488 ? 92.737  119.404 90.914  1.00 80.47  ? 488 MET A N    1 
ATOM   7407 C CA   . MET A 1 488 ? 91.494  118.689 90.645  1.00 80.47  ? 488 MET A CA   1 
ATOM   7408 C C    . MET A 1 488 ? 90.416  119.633 90.129  1.00 80.47  ? 488 MET A C    1 
ATOM   7409 O O    . MET A 1 488 ? 89.633  119.270 89.243  1.00 80.47  ? 488 MET A O    1 
ATOM   7410 C CB   . MET A 1 488 ? 91.012  117.976 91.911  1.00 80.47  ? 488 MET A CB   1 
ATOM   7411 C CG   . MET A 1 488 ? 91.684  116.634 92.180  1.00 80.47  ? 488 MET A CG   1 
ATOM   7412 S SD   . MET A 1 488 ? 91.421  115.418 90.873  1.00 80.47  ? 488 MET A SD   1 
ATOM   7413 C CE   . MET A 1 488 ? 89.633  115.381 90.779  1.00 80.47  ? 488 MET A CE   1 
ATOM   7414 H H    . MET A 1 488 ? 93.050  119.296 91.708  1.00 80.47  ? 488 MET A H    1 
ATOM   7415 H HA   . MET A 1 488 ? 91.665  118.016 89.968  1.00 80.47  ? 488 MET A HA   1 
ATOM   7416 H HB2  . MET A 1 488 ? 91.193  118.548 92.673  1.00 80.47  ? 488 MET A HB2  1 
ATOM   7417 H HB3  . MET A 1 488 ? 90.057  117.824 91.840  1.00 80.47  ? 488 MET A HB3  1 
ATOM   7418 H HG2  . MET A 1 488 ? 92.639  116.774 92.267  1.00 80.47  ? 488 MET A HG2  1 
ATOM   7419 H HG3  . MET A 1 488 ? 91.328  116.266 93.004  1.00 80.47  ? 488 MET A HG3  1 
ATOM   7420 H HE1  . MET A 1 488 ? 89.361  114.648 90.205  1.00 80.47  ? 488 MET A HE1  1 
ATOM   7421 H HE2  . MET A 1 488 ? 89.272  115.255 91.670  1.00 80.47  ? 488 MET A HE2  1 
ATOM   7422 H HE3  . MET A 1 488 ? 89.318  116.222 90.411  1.00 80.47  ? 488 MET A HE3  1 
ATOM   7423 N N    . GLU A 1 489 ? 90.362  120.853 90.667  1.00 82.24  ? 489 GLU A N    1 
ATOM   7424 C CA   . GLU A 1 489 ? 89.323  121.793 90.263  1.00 82.24  ? 489 GLU A CA   1 
ATOM   7425 C C    . GLU A 1 489 ? 89.428  122.125 88.780  1.00 82.24  ? 489 GLU A C    1 
ATOM   7426 O O    . GLU A 1 489 ? 88.420  122.154 88.064  1.00 82.24  ? 489 GLU A O    1 
ATOM   7427 C CB   . GLU A 1 489 ? 89.407  123.073 91.096  1.00 30.00  ? 489 GLU A CB   1 
ATOM   7428 H H    . GLU A 1 489 ? 90.908  121.154 91.260  1.00 82.24  ? 489 GLU A H    1 
ATOM   7429 H HA   . GLU A 1 489 ? 88.454  121.391 90.419  1.00 82.24  ? 489 GLU A HA   1 
ATOM   7430 N N    . VAL A 1 490 ? 90.646  122.380 88.297  1.00 82.84  ? 490 VAL A N    1 
ATOM   7431 C CA   . VAL A 1 490 ? 90.828  122.730 86.890  1.00 82.84  ? 490 VAL A CA   1 
ATOM   7432 C C    . VAL A 1 490 ? 90.401  121.568 86.001  1.00 82.84  ? 490 VAL A C    1 
ATOM   7433 O O    . VAL A 1 490 ? 89.510  121.700 85.154  1.00 82.84  ? 490 VAL A O    1 
ATOM   7434 C CB   . VAL A 1 490 ? 92.287  123.135 86.620  1.00 82.84  ? 490 VAL A CB   1 
ATOM   7435 H H    . VAL A 1 490 ? 91.372  122.357 88.757  1.00 82.84  ? 490 VAL A H    1 
ATOM   7436 H HA   . VAL A 1 490 ? 90.264  123.490 86.678  1.00 82.84  ? 490 VAL A HA   1 
ATOM   7437 N N    . TRP A 1 491 ? 91.031  120.411 86.186  1.00 81.93  ? 491 TRP A N    1 
ATOM   7438 C CA   . TRP A 1 491 ? 90.732  119.219 85.409  1.00 81.93  ? 491 TRP A CA   1 
ATOM   7439 C C    . TRP A 1 491 ? 90.658  118.022 86.345  1.00 81.93  ? 491 TRP A C    1 
ATOM   7440 O O    . TRP A 1 491 ? 91.355  117.966 87.362  1.00 81.93  ? 491 TRP A O    1 
ATOM   7441 C CB   . TRP A 1 491 ? 91.790  118.977 84.324  1.00 81.93  ? 491 TRP A CB   1 
ATOM   7442 C CG   . TRP A 1 491 ? 91.221  118.550 83.006  1.00 81.93  ? 491 TRP A CG   1 
ATOM   7443 C CD1  . TRP A 1 491 ? 91.146  117.279 82.519  1.00 81.93  ? 491 TRP A CD1  1 
ATOM   7444 C CD2  . TRP A 1 491 ? 90.651  119.399 82.001  1.00 81.93  ? 491 TRP A CD2  1 
ATOM   7445 N NE1  . TRP A 1 491 ? 90.563  117.281 81.274  1.00 81.93  ? 491 TRP A NE1  1 
ATOM   7446 C CE2  . TRP A 1 491 ? 90.250  118.571 80.934  1.00 81.93  ? 491 TRP A CE2  1 
ATOM   7447 C CE3  . TRP A 1 491 ? 90.439  120.777 81.900  1.00 81.93  ? 491 TRP A CE3  1 
ATOM   7448 C CZ2  . TRP A 1 491 ? 89.650  119.076 79.781  1.00 81.93  ? 491 TRP A CZ2  1 
ATOM   7449 C CZ3  . TRP A 1 491 ? 89.843  121.276 80.755  1.00 81.93  ? 491 TRP A CZ3  1 
ATOM   7450 C CH2  . TRP A 1 491 ? 89.456  120.427 79.712  1.00 81.93  ? 491 TRP A CH2  1 
ATOM   7451 H H    . TRP A 1 491 ? 91.650  120.292 86.771  1.00 81.93  ? 491 TRP A H    1 
ATOM   7452 H HA   . TRP A 1 491 ? 89.869  119.320 84.978  1.00 81.93  ? 491 TRP A HA   1 
ATOM   7453 H HB2  . TRP A 1 491 ? 92.287  119.798 84.183  1.00 81.93  ? 491 TRP A HB2  1 
ATOM   7454 H HB3  . TRP A 1 491 ? 92.388  118.277 84.625  1.00 81.93  ? 491 TRP A HB3  1 
ATOM   7455 H HD1  . TRP A 1 491 ? 91.445  116.519 82.965  1.00 81.93  ? 491 TRP A HD1  1 
ATOM   7456 H HE1  . TRP A 1 491 ? 90.418  116.587 80.788  1.00 81.93  ? 491 TRP A HE1  1 
ATOM   7457 H HE3  . TRP A 1 491 ? 90.694  121.348 82.589  1.00 81.93  ? 491 TRP A HE3  1 
ATOM   7458 H HZ2  . TRP A 1 491 ? 89.391  118.515 79.086  1.00 81.93  ? 491 TRP A HZ2  1 
ATOM   7459 H HZ3  . TRP A 1 491 ? 89.698  122.191 80.677  1.00 81.93  ? 491 TRP A HZ3  1 
ATOM   7460 H HH2  . TRP A 1 491 ? 89.058  120.791 78.954  1.00 81.93  ? 491 TRP A HH2  1 
ATOM   7461 N N    . GLN A 1 492 ? 89.800  117.064 85.993  1.00 81.77  ? 492 GLN A N    1 
ATOM   7462 C CA   . GLN A 1 492 ? 89.603  115.905 86.857  1.00 81.77  ? 492 GLN A CA   1 
ATOM   7463 C C    . GLN A 1 492 ? 90.873  115.068 86.962  1.00 81.77  ? 492 GLN A C    1 
ATOM   7464 O O    . GLN A 1 492 ? 91.203  114.568 88.043  1.00 81.77  ? 492 GLN A O    1 
ATOM   7465 C CB   . GLN A 1 492 ? 88.436  115.061 86.341  1.00 81.77  ? 492 GLN A CB   1 
ATOM   7466 C CG   . GLN A 1 492 ? 88.662  114.420 84.979  1.00 81.77  ? 492 GLN A CG   1 
ATOM   7467 C CD   . GLN A 1 492 ? 89.386  113.090 85.065  1.00 81.77  ? 492 GLN A CD   1 
ATOM   7468 O OE1  . GLN A 1 492 ? 89.569  112.538 86.149  1.00 81.77  ? 492 GLN A OE1  1 
ATOM   7469 N NE2  . GLN A 1 492 ? 89.805  112.571 83.917  1.00 81.77  ? 492 GLN A NE2  1 
ATOM   7470 H H    . GLN A 1 492 ? 89.330  117.061 85.273  1.00 81.77  ? 492 GLN A H    1 
ATOM   7471 H HA   . GLN A 1 492 ? 89.377  116.212 87.748  1.00 81.77  ? 492 GLN A HA   1 
ATOM   7472 H HB2  . GLN A 1 492 ? 88.258  114.352 86.979  1.00 81.77  ? 492 GLN A HB2  1 
ATOM   7473 H HB3  . GLN A 1 492 ? 87.655  115.632 86.268  1.00 81.77  ? 492 GLN A HB3  1 
ATOM   7474 H HG2  . GLN A 1 492 ? 87.802  114.265 84.557  1.00 81.77  ? 492 GLN A HG2  1 
ATOM   7475 H HG3  . GLN A 1 492 ? 89.196  115.017 84.432  1.00 81.77  ? 492 GLN A HG3  1 
ATOM   7476 H HE21 . GLN A 1 492 ? 90.222  111.819 83.913  1.00 81.77  ? 492 GLN A HE21 1 
ATOM   7477 H HE22 . GLN A 1 492 ? 89.660  112.987 83.179  1.00 81.77  ? 492 GLN A HE22 1 
ATOM   7478 N N    . GLY A 1 493 ? 91.592  114.900 85.856  1.00 80.65  ? 493 GLY A N    1 
ATOM   7479 C CA   . GLY A 1 493 ? 92.779  114.072 85.814  1.00 80.65  ? 493 GLY A CA   1 
ATOM   7480 C C    . GLY A 1 493 ? 94.100  114.809 85.801  1.00 80.65  ? 493 GLY A C    1 
ATOM   7481 O O    . GLY A 1 493 ? 95.141  114.169 85.606  1.00 80.65  ? 493 GLY A O    1 
ATOM   7482 H H    . GLY A 1 493 ? 91.403  115.268 85.102  1.00 80.65  ? 493 GLY A H    1 
ATOM   7483 H HA2  . GLY A 1 493 ? 92.779  113.483 86.585  1.00 80.65  ? 493 GLY A HA2  1 
ATOM   7484 H HA3  . GLY A 1 493 ? 92.743  113.516 85.020  1.00 80.65  ? 493 GLY A HA3  1 
ATOM   7485 N N    . LEU A 1 494 ? 94.104  116.125 86.009  1.00 80.03  ? 494 LEU A N    1 
ATOM   7486 C CA   . LEU A 1 494 ? 95.361  116.871 85.962  1.00 80.03  ? 494 LEU A CA   1 
ATOM   7487 C C    . LEU A 1 494 ? 96.364  116.389 87.001  1.00 80.03  ? 494 LEU A C    1 
ATOM   7488 O O    . LEU A 1 494 ? 97.540  116.199 86.647  1.00 80.03  ? 494 LEU A O    1 
ATOM   7489 C CB   . LEU A 1 494 ? 95.076  118.368 86.120  1.00 80.03  ? 494 LEU A CB   1 
ATOM   7490 C CG   . LEU A 1 494 ? 96.276  119.302 85.955  1.00 80.03  ? 494 LEU A CG   1 
ATOM   7491 C CD1  . LEU A 1 494 ? 96.855  119.186 84.556  1.00 80.03  ? 494 LEU A CD1  1 
ATOM   7492 C CD2  . LEU A 1 494 ? 95.883  120.739 86.254  1.00 80.03  ? 494 LEU A CD2  1 
ATOM   7493 H H    . LEU A 1 494 ? 93.407  116.602 86.170  1.00 80.03  ? 494 LEU A H    1 
ATOM   7494 H HA   . LEU A 1 494 ? 95.764  116.739 85.090  1.00 80.03  ? 494 LEU A HA   1 
ATOM   7495 H HB2  . LEU A 1 494 ? 94.422  118.624 85.451  1.00 80.03  ? 494 LEU A HB2  1 
ATOM   7496 H HB3  . LEU A 1 494 ? 94.710  118.524 87.003  1.00 80.03  ? 494 LEU A HB3  1 
ATOM   7497 H HG   . LEU A 1 494 ? 96.967  119.045 86.586  1.00 80.03  ? 494 LEU A HG   1 
ATOM   7498 H HD11 . LEU A 1 494 ? 97.513  119.886 84.428  1.00 80.03  ? 494 LEU A HD11 1 
ATOM   7499 H HD12 . LEU A 1 494 ? 97.272  118.316 84.456  1.00 80.03  ? 494 LEU A HD12 1 
ATOM   7500 H HD13 . LEU A 1 494 ? 96.137  119.285 83.910  1.00 80.03  ? 494 LEU A HD13 1 
ATOM   7501 H HD21 . LEU A 1 494 ? 96.687  121.271 86.361  1.00 80.03  ? 494 LEU A HD21 1 
ATOM   7502 H HD22 . LEU A 1 494 ? 95.355  121.081 85.515  1.00 80.03  ? 494 LEU A HD22 1 
ATOM   7503 H HD23 . LEU A 1 494 ? 95.361  120.762 87.072  1.00 80.03  ? 494 LEU A HD23 1 
ATOM   7504 N N    . PRO A 1 495 ? 95.996  116.175 88.268  1.00 78.21  ? 495 PRO A N    1 
ATOM   7505 C CA   . PRO A 1 495 ? 97.007  115.727 89.241  1.00 78.21  ? 495 PRO A CA   1 
ATOM   7506 C C    . PRO A 1 495 ? 97.678  114.424 88.849  1.00 78.21  ? 495 PRO A C    1 
ATOM   7507 O O    . PRO A 1 495 ? 98.881  114.254 89.086  1.00 78.21  ? 495 PRO A O    1 
ATOM   7508 C CB   . PRO A 1 495 ? 96.204  115.582 90.542  1.00 78.21  ? 495 PRO A CB   1 
ATOM   7509 C CG   . PRO A 1 495 ? 94.981  116.402 90.344  1.00 78.21  ? 495 PRO A CG   1 
ATOM   7510 C CD   . PRO A 1 495 ? 94.670  116.337 88.886  1.00 78.21  ? 495 PRO A CD   1 
ATOM   7511 H HA   . PRO A 1 495 ? 97.684  116.412 89.359  1.00 78.21  ? 495 PRO A HA   1 
ATOM   7512 H HB2  . PRO A 1 495 ? 95.974  114.650 90.682  1.00 78.21  ? 495 PRO A HB2  1 
ATOM   7513 H HB3  . PRO A 1 495 ? 96.726  115.922 91.286  1.00 78.21  ? 495 PRO A HB3  1 
ATOM   7514 H HG2  . PRO A 1 495 ? 94.253  116.025 90.862  1.00 78.21  ? 495 PRO A HG2  1 
ATOM   7515 H HG3  . PRO A 1 495 ? 95.153  117.317 90.617  1.00 78.21  ? 495 PRO A HG3  1 
ATOM   7516 H HD2  . PRO A 1 495 ? 94.110  115.569 88.693  1.00 78.21  ? 495 PRO A HD2  1 
ATOM   7517 H HD3  . PRO A 1 495 ? 94.254  117.162 88.596  1.00 78.21  ? 495 PRO A HD3  1 
ATOM   7518 N N    . LEU A 1 496 ? 96.930  113.493 88.255  1.00 78.75  ? 496 LEU A N    1 
ATOM   7519 C CA   . LEU A 1 496 ? 97.507  112.206 87.883  1.00 78.75  ? 496 LEU A CA   1 
ATOM   7520 C C    . LEU A 1 496 ? 98.607  112.373 86.840  1.00 78.75  ? 496 LEU A C    1 
ATOM   7521 O O    . LEU A 1 496 ? 99.670  111.742 86.934  1.00 78.75  ? 496 LEU A O    1 
ATOM   7522 C CB   . LEU A 1 496 ? 96.403  111.283 87.371  1.00 78.75  ? 496 LEU A CB   1 
ATOM   7523 C CG   . LEU A 1 496 ? 95.415  110.842 88.455  1.00 78.75  ? 496 LEU A CG   1 
ATOM   7524 C CD1  . LEU A 1 496 ? 94.083  110.415 87.853  1.00 78.75  ? 496 LEU A CD1  1 
ATOM   7525 C CD2  . LEU A 1 496 ? 96.014  109.715 89.285  1.00 78.75  ? 496 LEU A CD2  1 
ATOM   7526 H H    . LEU A 1 496 ? 96.097  113.583 88.059  1.00 78.75  ? 496 LEU A H    1 
ATOM   7527 H HA   . LEU A 1 496 ? 97.900  111.797 88.670  1.00 78.75  ? 496 LEU A HA   1 
ATOM   7528 H HB2  . LEU A 1 496 ? 95.899  111.750 86.686  1.00 78.75  ? 496 LEU A HB2  1 
ATOM   7529 H HB3  . LEU A 1 496 ? 96.808  110.486 86.994  1.00 78.75  ? 496 LEU A HB3  1 
ATOM   7530 H HG   . LEU A 1 496 ? 95.246  111.590 89.048  1.00 78.75  ? 496 LEU A HG   1 
ATOM   7531 H HD11 . LEU A 1 496 ? 93.534  110.026 88.552  1.00 78.75  ? 496 LEU A HD11 1 
ATOM   7532 H HD12 . LEU A 1 496 ? 93.640  111.193 87.481  1.00 78.75  ? 496 LEU A HD12 1 
ATOM   7533 H HD13 . LEU A 1 496 ? 94.244  109.760 87.157  1.00 78.75  ? 496 LEU A HD13 1 
ATOM   7534 H HD21 . LEU A 1 496 ? 95.383  109.463 89.977  1.00 78.75  ? 496 LEU A HD21 1 
ATOM   7535 H HD22 . LEU A 1 496 ? 96.190  108.958 88.705  1.00 78.75  ? 496 LEU A HD22 1 
ATOM   7536 H HD23 . LEU A 1 496 ? 96.841  110.024 89.687  1.00 78.75  ? 496 LEU A HD23 1 
ATOM   7537 N N    . ILE A 1 497 ? 98.373  113.226 85.841  1.00 75.53  ? 497 ILE A N    1 
ATOM   7538 C CA   . ILE A 1 497 ? 99.403  113.507 84.846  1.00 75.53  ? 497 ILE A CA   1 
ATOM   7539 C C    . ILE A 1 497 ? 100.637 114.091 85.519  1.00 75.53  ? 497 ILE A C    1 
ATOM   7540 O O    . ILE A 1 497 ? 101.776 113.746 85.175  1.00 75.53  ? 497 ILE A O    1 
ATOM   7541 C CB   . ILE A 1 497 ? 98.850  114.454 83.763  1.00 75.53  ? 497 ILE A CB   1 
ATOM   7542 C CG1  . ILE A 1 497 ? 97.666  113.811 83.033  1.00 75.53  ? 497 ILE A CG1  1 
ATOM   7543 C CG2  . ILE A 1 497 ? 99.945  114.838 82.779  1.00 75.53  ? 497 ILE A CG2  1 
ATOM   7544 C CD1  . ILE A 1 497 ? 98.036  112.633 82.150  1.00 75.53  ? 497 ILE A CD1  1 
ATOM   7545 H H    . ILE A 1 497 ? 97.635  113.652 85.722  1.00 75.53  ? 497 ILE A H    1 
ATOM   7546 H HA   . ILE A 1 497 ? 99.664  112.678 84.419  1.00 75.53  ? 497 ILE A HA   1 
ATOM   7547 H HB   . ILE A 1 497 ? 98.536  115.262 84.198  1.00 75.53  ? 497 ILE A HB   1 
ATOM   7548 H HG12 . ILE A 1 497 ? 97.024  113.497 83.688  1.00 75.53  ? 497 ILE A HG12 1 
ATOM   7549 H HG13 . ILE A 1 497 ? 97.251  114.481 82.467  1.00 75.53  ? 497 ILE A HG13 1 
ATOM   7550 H HG21 . ILE A 1 497 ? 99.534  115.215 81.986  1.00 75.53  ? 497 ILE A HG21 1 
ATOM   7551 H HG22 . ILE A 1 497 ? 100.527 115.495 83.192  1.00 75.53  ? 497 ILE A HG22 1 
ATOM   7552 H HG23 . ILE A 1 497 ? 100.451 114.045 82.544  1.00 75.53  ? 497 ILE A HG23 1 
ATOM   7553 H HD11 . ILE A 1 497 ? 97.222  112.193 81.858  1.00 75.53  ? 497 ILE A HD11 1 
ATOM   7554 H HD12 . ILE A 1 497 ? 98.529  112.956 81.380  1.00 75.53  ? 497 ILE A HD12 1 
ATOM   7555 H HD13 . ILE A 1 497 ? 98.581  112.010 82.656  1.00 75.53  ? 497 ILE A HD13 1 
ATOM   7556 N N    . LEU A 1 498 ? 100.431 114.990 86.484  1.00 71.17  ? 498 LEU A N    1 
ATOM   7557 C CA   . LEU A 1 498 ? 101.558 115.590 87.188  1.00 71.17  ? 498 LEU A CA   1 
ATOM   7558 C C    . LEU A 1 498 ? 102.370 114.534 87.924  1.00 71.17  ? 498 LEU A C    1 
ATOM   7559 O O    . LEU A 1 498 ? 103.605 114.526 87.848  1.00 71.17  ? 498 LEU A O    1 
ATOM   7560 C CB   . LEU A 1 498 ? 101.054 116.656 88.160  1.00 71.17  ? 498 LEU A CB   1 
ATOM   7561 C CG   . LEU A 1 498 ? 102.088 117.252 89.117  1.00 71.17  ? 498 LEU A CG   1 
ATOM   7562 C CD1  . LEU A 1 498 ? 101.879 118.750 89.252  1.00 71.17  ? 498 LEU A CD1  1 
ATOM   7563 C CD2  . LEU A 1 498 ? 102.014 116.584 90.482  1.00 71.17  ? 498 LEU A CD2  1 
ATOM   7564 H H    . LEU A 1 498 ? 99.659  115.263 86.746  1.00 71.17  ? 498 LEU A H    1 
ATOM   7565 H HA   . LEU A 1 498 ? 102.138 116.026 86.544  1.00 71.17  ? 498 LEU A HA   1 
ATOM   7566 H HB2  . LEU A 1 498 ? 100.686 117.389 87.643  1.00 71.17  ? 498 LEU A HB2  1 
ATOM   7567 H HB3  . LEU A 1 498 ? 100.352 116.264 88.703  1.00 71.17  ? 498 LEU A HB3  1 
ATOM   7568 H HG   . LEU A 1 498 ? 102.977 117.104 88.757  1.00 71.17  ? 498 LEU A HG   1 
ATOM   7569 H HD11 . LEU A 1 498 ? 102.503 119.097 89.908  1.00 71.17  ? 498 LEU A HD11 1 
ATOM   7570 H HD12 . LEU A 1 498 ? 102.036 119.169 88.391  1.00 71.17  ? 498 LEU A HD12 1 
ATOM   7571 H HD13 . LEU A 1 498 ? 100.968 118.916 89.540  1.00 71.17  ? 498 LEU A HD13 1 
ATOM   7572 H HD21 . LEU A 1 498 ? 102.667 116.996 91.069  1.00 71.17  ? 498 LEU A HD21 1 
ATOM   7573 H HD22 . LEU A 1 498 ? 101.122 116.705 90.845  1.00 71.17  ? 498 LEU A HD22 1 
ATOM   7574 H HD23 . LEU A 1 498 ? 102.206 115.639 90.386  1.00 71.17  ? 498 LEU A HD23 1 
ATOM   7575 N N    . PHE A 1 499 ? 101.697 113.627 88.634  1.00 69.09  ? 499 PHE A N    1 
ATOM   7576 C CA   . PHE A 1 499 ? 102.424 112.583 89.350  1.00 69.09  ? 499 PHE A CA   1 
ATOM   7577 C C    . PHE A 1 499 ? 103.212 111.709 88.385  1.00 69.09  ? 499 PHE A C    1 
ATOM   7578 O O    . PHE A 1 499 ? 104.381 111.387 88.637  1.00 69.09  ? 499 PHE A O    1 
ATOM   7579 C CB   . PHE A 1 499 ? 101.460 111.726 90.170  1.00 69.09  ? 499 PHE A CB   1 
ATOM   7580 C CG   . PHE A 1 499 ? 100.859 112.441 91.342  1.00 69.09  ? 499 PHE A CG   1 
ATOM   7581 C CD1  . PHE A 1 499 ? 101.660 112.929 92.357  1.00 69.09  ? 499 PHE A CD1  1 
ATOM   7582 C CD2  . PHE A 1 499 ? 99.491  112.610 91.438  1.00 69.09  ? 499 PHE A CD2  1 
ATOM   7583 C CE1  . PHE A 1 499 ? 101.109 113.583 93.438  1.00 69.09  ? 499 PHE A CE1  1 
ATOM   7584 C CE2  . PHE A 1 499 ? 98.935  113.263 92.517  1.00 69.09  ? 499 PHE A CE2  1 
ATOM   7585 C CZ   . PHE A 1 499 ? 99.745  113.749 93.518  1.00 69.09  ? 499 PHE A CZ   1 
ATOM   7586 H H    . PHE A 1 499 ? 100.842 113.594 88.715  1.00 69.09  ? 499 PHE A H    1 
ATOM   7587 H HA   . PHE A 1 499 ? 103.054 112.998 89.960  1.00 69.09  ? 499 PHE A HA   1 
ATOM   7588 H HB2  . PHE A 1 499 ? 100.734 111.436 89.596  1.00 69.09  ? 499 PHE A HB2  1 
ATOM   7589 H HB3  . PHE A 1 499 ? 101.939 110.954 90.508  1.00 69.09  ? 499 PHE A HB3  1 
ATOM   7590 H HD1  . PHE A 1 499 ? 102.582 112.820 92.307  1.00 69.09  ? 499 PHE A HD1  1 
ATOM   7591 H HD2  . PHE A 1 499 ? 98.940  112.284 90.764  1.00 69.09  ? 499 PHE A HD2  1 
ATOM   7592 H HE1  . PHE A 1 499 ? 101.658 113.911 94.113  1.00 69.09  ? 499 PHE A HE1  1 
ATOM   7593 H HE2  . PHE A 1 499 ? 98.014  113.374 92.569  1.00 69.09  ? 499 PHE A HE2  1 
ATOM   7594 H HZ   . PHE A 1 499 ? 99.372  114.190 94.247  1.00 69.09  ? 499 PHE A HZ   1 
ATOM   7595 N N    . THR A 1 500 ? 102.591 111.317 87.270  1.00 72.74  ? 500 THR A N    1 
ATOM   7596 C CA   . THR A 1 500 ? 103.275 110.431 86.333  1.00 72.74  ? 500 THR A CA   1 
ATOM   7597 C C    . THR A 1 500 ? 104.493 111.107 85.714  1.00 72.74  ? 500 THR A C    1 
ATOM   7598 O O    . THR A 1 500 ? 105.554 110.484 85.586  1.00 72.74  ? 500 THR A O    1 
ATOM   7599 C CB   . THR A 1 500 ? 102.309 109.964 85.246  1.00 72.74  ? 500 THR A CB   1 
ATOM   7600 O OG1  . THR A 1 500 ? 101.770 111.100 84.559  1.00 72.74  ? 500 THR A OG1  1 
ATOM   7601 C CG2  . THR A 1 500 ? 101.176 109.155 85.858  1.00 72.74  ? 500 THR A CG2  1 
ATOM   7602 H H    . THR A 1 500 ? 101.794 111.543 87.040  1.00 72.74  ? 500 THR A H    1 
ATOM   7603 H HA   . THR A 1 500 ? 103.584 109.646 86.813  1.00 72.74  ? 500 THR A HA   1 
ATOM   7604 H HB   . THR A 1 500 ? 102.782 109.400 84.615  1.00 72.74  ? 500 THR A HB   1 
ATOM   7605 H HG1  . THR A 1 500 ? 101.342 111.582 85.097  1.00 72.74  ? 500 THR A HG1  1 
ATOM   7606 H HG21 . THR A 1 500 ? 100.512 108.949 85.181  1.00 72.74  ? 500 THR A HG21 1 
ATOM   7607 H HG22 . THR A 1 500 ? 101.522 108.327 86.225  1.00 72.74  ? 500 THR A HG22 1 
ATOM   7608 H HG23 . THR A 1 500 ? 100.752 109.658 86.570  1.00 72.74  ? 500 THR A HG23 1 
ATOM   7609 N N    . VAL A 1 501 ? 104.369 112.380 85.328  1.00 68.38  ? 501 VAL A N    1 
ATOM   7610 C CA   . VAL A 1 501 ? 105.510 113.065 84.726  1.00 68.38  ? 501 VAL A CA   1 
ATOM   7611 C C    . VAL A 1 501 ? 106.610 113.275 85.759  1.00 68.38  ? 501 VAL A C    1 
ATOM   7612 O O    . VAL A 1 501 ? 107.800 113.141 85.449  1.00 68.38  ? 501 VAL A O    1 
ATOM   7613 C CB   . VAL A 1 501 ? 105.078 114.395 84.079  1.00 68.38  ? 501 VAL A CB   1 
ATOM   7614 C CG1  . VAL A 1 501 ? 104.544 115.365 85.118  1.00 68.38  ? 501 VAL A CG1  1 
ATOM   7615 C CG2  . VAL A 1 501 ? 106.243 115.015 83.321  1.00 68.38  ? 501 VAL A CG2  1 
ATOM   7616 H H    . VAL A 1 501 ? 103.656 112.855 85.400  1.00 68.38  ? 501 VAL A H    1 
ATOM   7617 H HA   . VAL A 1 501 ? 105.872 112.503 84.024  1.00 68.38  ? 501 VAL A HA   1 
ATOM   7618 H HB   . VAL A 1 501 ? 104.368 114.219 83.442  1.00 68.38  ? 501 VAL A HB   1 
ATOM   7619 H HG11 . VAL A 1 501 ? 104.263 116.178 84.669  1.00 68.38  ? 501 VAL A HG11 1 
ATOM   7620 H HG12 . VAL A 1 501 ? 103.788 114.958 85.563  1.00 68.38  ? 501 VAL A HG12 1 
ATOM   7621 H HG13 . VAL A 1 501 ? 105.240 115.571 85.760  1.00 68.38  ? 501 VAL A HG13 1 
ATOM   7622 H HG21 . VAL A 1 501 ? 105.918 115.770 82.806  1.00 68.38  ? 501 VAL A HG21 1 
ATOM   7623 H HG22 . VAL A 1 501 ? 106.913 115.313 83.956  1.00 68.38  ? 501 VAL A HG22 1 
ATOM   7624 H HG23 . VAL A 1 501 ? 106.623 114.349 82.726  1.00 68.38  ? 501 VAL A HG23 1 
ATOM   7625 N N    . VAL A 1 502 ? 106.241 113.594 87.003  1.00 65.10  ? 502 VAL A N    1 
ATOM   7626 C CA   . VAL A 1 502 ? 107.246 113.736 88.052  1.00 65.10  ? 502 VAL A CA   1 
ATOM   7627 C C    . VAL A 1 502 ? 108.021 112.436 88.210  1.00 65.10  ? 502 VAL A C    1 
ATOM   7628 O O    . VAL A 1 502 ? 109.259 112.425 88.237  1.00 65.10  ? 502 VAL A O    1 
ATOM   7629 C CB   . VAL A 1 502 ? 106.583 114.161 89.375  1.00 65.10  ? 502 VAL A CB   1 
ATOM   7630 C CG1  . VAL A 1 502 ? 107.528 113.949 90.543  1.00 65.10  ? 502 VAL A CG1  1 
ATOM   7631 C CG2  . VAL A 1 502 ? 106.152 115.615 89.310  1.00 65.10  ? 502 VAL A CG2  1 
ATOM   7632 H H    . VAL A 1 502 ? 105.431 113.730 87.258  1.00 65.10  ? 502 VAL A H    1 
ATOM   7633 H HA   . VAL A 1 502 ? 107.875 114.429 87.795  1.00 65.10  ? 502 VAL A HA   1 
ATOM   7634 H HB   . VAL A 1 502 ? 105.793 113.618 89.524  1.00 65.10  ? 502 VAL A HB   1 
ATOM   7635 H HG11 . VAL A 1 502 ? 107.208 114.466 91.299  1.00 65.10  ? 502 VAL A HG11 1 
ATOM   7636 H HG12 . VAL A 1 502 ? 107.544 113.007 90.775  1.00 65.10  ? 502 VAL A HG12 1 
ATOM   7637 H HG13 . VAL A 1 502 ? 108.415 114.248 90.291  1.00 65.10  ? 502 VAL A HG13 1 
ATOM   7638 H HG21 . VAL A 1 502 ? 105.566 115.802 90.060  1.00 65.10  ? 502 VAL A HG21 1 
ATOM   7639 H HG22 . VAL A 1 502 ? 106.940 116.179 89.357  1.00 65.10  ? 502 VAL A HG22 1 
ATOM   7640 H HG23 . VAL A 1 502 ? 105.682 115.769 88.476  1.00 65.10  ? 502 VAL A HG23 1 
ATOM   7641 N N    . GLY A 1 503 ? 107.301 111.316 88.301  1.00 64.15  ? 503 GLY A N    1 
ATOM   7642 C CA   . GLY A 1 503 ? 107.971 110.036 88.459  1.00 64.15  ? 503 GLY A CA   1 
ATOM   7643 C C    . GLY A 1 503 ? 108.876 109.699 87.290  1.00 64.15  ? 503 GLY A C    1 
ATOM   7644 O O    . GLY A 1 503 ? 110.016 109.267 87.479  1.00 64.15  ? 503 GLY A O    1 
ATOM   7645 H H    . GLY A 1 503 ? 106.443 111.275 88.275  1.00 64.15  ? 503 GLY A H    1 
ATOM   7646 H HA2  . GLY A 1 503 ? 108.506 110.047 89.269  1.00 64.15  ? 503 GLY A HA2  1 
ATOM   7647 H HA3  . GLY A 1 503 ? 107.306 109.334 88.542  1.00 64.15  ? 503 GLY A HA3  1 
ATOM   7648 N N    . LEU A 1 504 ? 108.384 109.894 86.065  1.00 63.41  ? 504 LEU A N    1 
ATOM   7649 C CA   . LEU A 1 504 ? 109.179 109.552 84.891  1.00 63.41  ? 504 LEU A CA   1 
ATOM   7650 C C    . LEU A 1 504 ? 110.440 110.405 84.817  1.00 63.41  ? 504 LEU A C    1 
ATOM   7651 O O    . LEU A 1 504 ? 111.531 109.897 84.531  1.00 63.41  ? 504 LEU A O    1 
ATOM   7652 C CB   . LEU A 1 504 ? 108.335 109.715 83.627  1.00 63.41  ? 504 LEU A CB   1 
ATOM   7653 C CG   . LEU A 1 504 ? 109.013 109.399 82.293  1.00 63.41  ? 504 LEU A CG   1 
ATOM   7654 C CD1  . LEU A 1 504 ? 108.024 108.730 81.353  1.00 63.41  ? 504 LEU A CD1  1 
ATOM   7655 C CD2  . LEU A 1 504 ? 109.571 110.660 81.654  1.00 63.41  ? 504 LEU A CD2  1 
ATOM   7656 H H    . LEU A 1 504 ? 107.606 110.216 85.891  1.00 63.41  ? 504 LEU A H    1 
ATOM   7657 H HA   . LEU A 1 504 ? 109.451 108.623 84.952  1.00 63.41  ? 504 LEU A HA   1 
ATOM   7658 H HB2  . LEU A 1 504 ? 107.566 109.128 83.702  1.00 63.41  ? 504 LEU A HB2  1 
ATOM   7659 H HB3  . LEU A 1 504 ? 108.032 110.635 83.583  1.00 63.41  ? 504 LEU A HB3  1 
ATOM   7660 H HG   . LEU A 1 504 ? 109.748 108.785 82.444  1.00 63.41  ? 504 LEU A HG   1 
ATOM   7661 H HD11 . LEU A 1 504 ? 108.456 108.574 80.498  1.00 63.41  ? 504 LEU A HD11 1 
ATOM   7662 H HD12 . LEU A 1 504 ? 107.741 107.886 81.740  1.00 63.41  ? 504 LEU A HD12 1 
ATOM   7663 H HD13 . LEU A 1 504 ? 107.258 109.313 81.235  1.00 63.41  ? 504 LEU A HD13 1 
ATOM   7664 H HD21 . LEU A 1 504 ? 109.981 110.429 80.806  1.00 63.41  ? 504 LEU A HD21 1 
ATOM   7665 H HD22 . LEU A 1 504 ? 108.844 111.286 81.507  1.00 63.41  ? 504 LEU A HD22 1 
ATOM   7666 H HD23 . LEU A 1 504 ? 110.232 111.054 82.243  1.00 63.41  ? 504 LEU A HD23 1 
ATOM   7667 N N    . VAL A 1 505 ? 110.311 111.710 85.074  1.00 63.01  ? 505 VAL A N    1 
ATOM   7668 C CA   . VAL A 1 505 ? 111.468 112.596 84.985  1.00 63.01  ? 505 VAL A CA   1 
ATOM   7669 C C    . VAL A 1 505 ? 112.480 112.269 86.074  1.00 63.01  ? 505 VAL A C    1 
ATOM   7670 O O    . VAL A 1 505 ? 113.694 112.287 85.836  1.00 63.01  ? 505 VAL A O    1 
ATOM   7671 C CB   . VAL A 1 505 ? 111.021 114.067 85.050  1.00 63.01  ? 505 VAL A CB   1 
ATOM   7672 C CG1  . VAL A 1 505 ? 112.228 114.982 85.145  1.00 63.01  ? 505 VAL A CG1  1 
ATOM   7673 C CG2  . VAL A 1 505 ? 110.184 114.418 83.831  1.00 63.01  ? 505 VAL A CG2  1 
ATOM   7674 H H    . VAL A 1 505 ? 109.578 112.098 85.299  1.00 63.01  ? 505 VAL A H    1 
ATOM   7675 H HA   . VAL A 1 505 ? 111.901 112.457 84.128  1.00 63.01  ? 505 VAL A HA   1 
ATOM   7676 H HB   . VAL A 1 505 ? 110.476 114.200 85.841  1.00 63.01  ? 505 VAL A HB   1 
ATOM   7677 H HG11 . VAL A 1 505 ? 111.959 115.881 84.902  1.00 63.01  ? 505 VAL A HG11 1 
ATOM   7678 H HG12 . VAL A 1 505 ? 112.564 114.973 86.055  1.00 63.01  ? 505 VAL A HG12 1 
ATOM   7679 H HG13 . VAL A 1 505 ? 112.912 114.666 84.534  1.00 63.01  ? 505 VAL A HG13 1 
ATOM   7680 H HG21 . VAL A 1 505 ? 109.908 115.345 83.894  1.00 63.01  ? 505 VAL A HG21 1 
ATOM   7681 H HG22 . VAL A 1 505 ? 110.719 114.285 83.033  1.00 63.01  ? 505 VAL A HG22 1 
ATOM   7682 H HG23 . VAL A 1 505 ? 109.405 113.842 83.804  1.00 63.01  ? 505 VAL A HG23 1 
ATOM   7683 N N    . ALA A 1 506 ? 112.008 111.966 87.286  1.00 60.05  ? 506 ALA A N    1 
ATOM   7684 C CA   . ALA A 1 506 ? 112.930 111.578 88.347  1.00 60.05  ? 506 ALA A CA   1 
ATOM   7685 C C    . ALA A 1 506 ? 113.663 110.292 87.986  1.00 60.05  ? 506 ALA A C    1 
ATOM   7686 O O    . ALA A 1 506 ? 114.882 110.182 88.172  1.00 60.05  ? 506 ALA A O    1 
ATOM   7687 C CB   . ALA A 1 506 ? 112.173 111.416 89.664  1.00 60.05  ? 506 ALA A CB   1 
ATOM   7688 H H    . ALA A 1 506 ? 111.178 111.976 87.512  1.00 60.05  ? 506 ALA A H    1 
ATOM   7689 H HA   . ALA A 1 506 ? 113.591 112.279 88.464  1.00 60.05  ? 506 ALA A HA   1 
ATOM   7690 H HB1  . ALA A 1 506 ? 112.806 111.212 90.369  1.00 60.05  ? 506 ALA A HB1  1 
ATOM   7691 H HB2  . ALA A 1 506 ? 111.709 112.244 89.863  1.00 60.05  ? 506 ALA A HB2  1 
ATOM   7692 H HB3  . ALA A 1 506 ? 111.533 110.693 89.571  1.00 60.05  ? 506 ALA A HB3  1 
ATOM   7693 N N    . GLY A 1 507 ? 112.932 109.302 87.469  1.00 60.38  ? 507 GLY A N    1 
ATOM   7694 C CA   . GLY A 1 507 ? 113.573 108.062 87.067  1.00 60.38  ? 507 GLY A CA   1 
ATOM   7695 C C    . GLY A 1 507 ? 114.616 108.274 85.989  1.00 60.38  ? 507 GLY A C    1 
ATOM   7696 O O    . GLY A 1 507 ? 115.691 107.672 86.023  1.00 60.38  ? 507 GLY A O    1 
ATOM   7697 H H    . GLY A 1 507 ? 112.082 109.327 87.346  1.00 60.38  ? 507 GLY A H    1 
ATOM   7698 H HA2  . GLY A 1 507 ? 114.002 107.654 87.836  1.00 60.38  ? 507 GLY A HA2  1 
ATOM   7699 H HA3  . GLY A 1 507 ? 112.902 107.448 86.728  1.00 60.38  ? 507 GLY A HA3  1 
ATOM   7700 N N    . GLY A 1 508 ? 114.314 109.136 85.019  1.00 61.00  ? 508 GLY A N    1 
ATOM   7701 C CA   . GLY A 1 508 ? 115.292 109.434 83.986  1.00 61.00  ? 508 GLY A CA   1 
ATOM   7702 C C    . GLY A 1 508 ? 116.518 110.145 84.527  1.00 61.00  ? 508 GLY A C    1 
ATOM   7703 O O    . GLY A 1 508 ? 117.644 109.866 84.109  1.00 61.00  ? 508 GLY A O    1 
ATOM   7704 H H    . GLY A 1 508 ? 113.566 109.552 84.939  1.00 61.00  ? 508 GLY A H    1 
ATOM   7705 H HA2  . GLY A 1 508 ? 115.578 108.608 83.566  1.00 61.00  ? 508 GLY A HA2  1 
ATOM   7706 H HA3  . GLY A 1 508 ? 114.885 109.997 83.308  1.00 61.00  ? 508 GLY A HA3  1 
ATOM   7707 N N    . MET A 1 509 ? 116.317 111.076 85.463  1.00 60.26  ? 509 MET A N    1 
ATOM   7708 C CA   . MET A 1 509 ? 117.439 111.852 85.981  1.00 60.26  ? 509 MET A CA   1 
ATOM   7709 C C    . MET A 1 509 ? 118.305 111.036 86.932  1.00 60.26  ? 509 MET A C    1 
ATOM   7710 O O    . MET A 1 509 ? 119.477 111.370 87.138  1.00 60.26  ? 509 MET A O    1 
ATOM   7711 C CB   . MET A 1 509 ? 116.925 113.106 86.683  1.00 60.26  ? 509 MET A CB   1 
ATOM   7712 C CG   . MET A 1 509 ? 118.011 114.088 87.089  1.00 60.26  ? 509 MET A CG   1 
ATOM   7713 S SD   . MET A 1 509 ? 118.871 114.810 85.678  1.00 60.26  ? 509 MET A SD   1 
ATOM   7714 C CE   . MET A 1 509 ? 120.303 113.743 85.549  1.00 60.26  ? 509 MET A CE   1 
ATOM   7715 H H    . MET A 1 509 ? 115.554 111.272 85.808  1.00 60.26  ? 509 MET A H    1 
ATOM   7716 H HA   . MET A 1 509 ? 117.982 112.136 85.230  1.00 60.26  ? 509 MET A HA   1 
ATOM   7717 H HB2  . MET A 1 509 ? 116.317 113.570 86.086  1.00 60.26  ? 509 MET A HB2  1 
ATOM   7718 H HB3  . MET A 1 509 ? 116.453 112.840 87.488  1.00 60.26  ? 509 MET A HB3  1 
ATOM   7719 H HG2  . MET A 1 509 ? 117.607 114.812 87.593  1.00 60.26  ? 509 MET A HG2  1 
ATOM   7720 H HG3  . MET A 1 509 ? 118.667 113.631 87.638  1.00 60.26  ? 509 MET A HG3  1 
ATOM   7721 H HE1  . MET A 1 509 ? 120.889 114.089 84.858  1.00 60.26  ? 509 MET A HE1  1 
ATOM   7722 H HE2  . MET A 1 509 ? 120.767 113.735 86.401  1.00 60.26  ? 509 MET A HE2  1 
ATOM   7723 H HE3  . MET A 1 509 ? 120.018 112.847 85.318  1.00 60.26  ? 509 MET A HE3  1 
ATOM   7724 N N    . THR A 1 510 ? 117.749 109.980 87.533  1.00 57.68  ? 510 THR A N    1 
ATOM   7725 C CA   . THR A 1 510 ? 118.543 109.151 88.438  1.00 57.68  ? 510 THR A CA   1 
ATOM   7726 C C    . THR A 1 510 ? 119.750 108.535 87.743  1.00 57.68  ? 510 THR A C    1 
ATOM   7727 O O    . THR A 1 510 ? 120.801 108.359 88.370  1.00 57.68  ? 510 THR A O    1 
ATOM   7728 C CB   . THR A 1 510 ? 117.684 108.038 89.033  1.00 57.68  ? 510 THR A CB   1 
ATOM   7729 O OG1  . THR A 1 510 ? 117.003 107.340 87.983  1.00 57.68  ? 510 THR A OG1  1 
ATOM   7730 C CG2  . THR A 1 510 ? 116.679 108.607 90.003  1.00 57.68  ? 510 THR A CG2  1 
ATOM   7731 H H    . THR A 1 510 ? 116.932 109.730 87.437  1.00 57.68  ? 510 THR A H    1 
ATOM   7732 H HA   . THR A 1 510 ? 118.866 109.701 89.168  1.00 57.68  ? 510 THR A HA   1 
ATOM   7733 H HB   . THR A 1 510 ? 118.254 107.416 89.513  1.00 57.68  ? 510 THR A HB   1 
ATOM   7734 H HG1  . THR A 1 510 ? 116.453 107.851 87.611  1.00 57.68  ? 510 THR A HG1  1 
ATOM   7735 H HG21 . THR A 1 510 ? 115.899 108.033 90.051  1.00 57.68  ? 510 THR A HG21 1 
ATOM   7736 H HG22 . THR A 1 510 ? 117.081 108.669 90.879  1.00 57.68  ? 510 THR A HG22 1 
ATOM   7737 H HG23 . THR A 1 510 ? 116.407 109.493 89.723  1.00 57.68  ? 510 THR A HG23 1 
ATOM   7738 N N    . LEU A 1 511 ? 119.620 108.193 86.460  1.00 57.69  ? 511 LEU A N    1 
ATOM   7739 C CA   . LEU A 1 511 ? 120.683 107.465 85.774  1.00 57.69  ? 511 LEU A CA   1 
ATOM   7740 C C    . LEU A 1 511 ? 122.010 108.213 85.841  1.00 57.69  ? 511 LEU A C    1 
ATOM   7741 O O    . LEU A 1 511 ? 123.076 107.593 85.921  1.00 57.69  ? 511 LEU A O    1 
ATOM   7742 C CB   . LEU A 1 511 ? 120.285 107.215 84.319  1.00 57.69  ? 511 LEU A CB   1 
ATOM   7743 C CG   . LEU A 1 511 ? 121.327 106.503 83.454  1.00 57.69  ? 511 LEU A CG   1 
ATOM   7744 C CD1  . LEU A 1 511 ? 121.592 105.102 83.975  1.00 57.69  ? 511 LEU A CD1  1 
ATOM   7745 C CD2  . LEU A 1 511 ? 120.882 106.460 82.002  1.00 57.69  ? 511 LEU A CD2  1 
ATOM   7746 H H    . LEU A 1 511 ? 118.935 108.370 85.971  1.00 57.69  ? 511 LEU A H    1 
ATOM   7747 H HA   . LEU A 1 511 ? 120.802 106.605 86.205  1.00 57.69  ? 511 LEU A HA   1 
ATOM   7748 H HB2  . LEU A 1 511 ? 119.482 106.671 84.311  1.00 57.69  ? 511 LEU A HB2  1 
ATOM   7749 H HB3  . LEU A 1 511 ? 120.099 108.071 83.901  1.00 57.69  ? 511 LEU A HB3  1 
ATOM   7750 H HG   . LEU A 1 511 ? 122.162 106.996 83.490  1.00 57.69  ? 511 LEU A HG   1 
ATOM   7751 H HD11 . LEU A 1 511 ? 122.220 104.660 83.382  1.00 57.69  ? 511 LEU A HD11 1 
ATOM   7752 H HD12 . LEU A 1 511 ? 121.966 105.161 84.868  1.00 57.69  ? 511 LEU A HD12 1 
ATOM   7753 H HD13 . LEU A 1 511 ? 120.756 104.610 83.997  1.00 57.69  ? 511 LEU A HD13 1 
ATOM   7754 H HD21 . LEU A 1 511 ? 121.565 106.013 81.477  1.00 57.69  ? 511 LEU A HD21 1 
ATOM   7755 H HD22 . LEU A 1 511 ? 120.046 105.973 81.941  1.00 57.69  ? 511 LEU A HD22 1 
ATOM   7756 H HD23 . LEU A 1 511 ? 120.761 107.368 81.682  1.00 57.69  ? 511 LEU A HD23 1 
ATOM   7757 N N    . LEU A 1 512 ? 121.969 109.545 85.811  1.00 59.00  ? 512 LEU A N    1 
ATOM   7758 C CA   . LEU A 1 512 ? 123.200 110.324 85.773  1.00 59.00  ? 512 LEU A CA   1 
ATOM   7759 C C    . LEU A 1 512 ? 123.959 110.299 87.092  1.00 59.00  ? 512 LEU A C    1 
ATOM   7760 O O    . LEU A 1 512 ? 125.107 110.753 87.131  1.00 59.00  ? 512 LEU A O    1 
ATOM   7761 C CB   . LEU A 1 512 ? 122.892 111.773 85.389  1.00 59.00  ? 512 LEU A CB   1 
ATOM   7762 C CG   . LEU A 1 512 ? 124.098 112.660 85.068  1.00 59.00  ? 512 LEU A CG   1 
ATOM   7763 C CD1  . LEU A 1 512 ? 124.950 112.044 83.967  1.00 59.00  ? 512 LEU A CD1  1 
ATOM   7764 C CD2  . LEU A 1 512 ? 123.645 114.053 84.670  1.00 59.00  ? 512 LEU A CD2  1 
ATOM   7765 H H    . LEU A 1 512 ? 121.249 110.016 85.811  1.00 59.00  ? 512 LEU A H    1 
ATOM   7766 H HA   . LEU A 1 512 ? 123.779 109.948 85.093  1.00 59.00  ? 512 LEU A HA   1 
ATOM   7767 H HB2  . LEU A 1 512 ? 122.319 111.768 84.606  1.00 59.00  ? 512 LEU A HB2  1 
ATOM   7768 H HB3  . LEU A 1 512 ? 122.424 112.186 86.130  1.00 59.00  ? 512 LEU A HB3  1 
ATOM   7769 H HG   . LEU A 1 512 ? 124.649 112.745 85.861  1.00 59.00  ? 512 LEU A HG   1 
ATOM   7770 H HD11 . LEU A 1 512 ? 125.565 112.714 83.631  1.00 59.00  ? 512 LEU A HD11 1 
ATOM   7771 H HD12 . LEU A 1 512 ? 125.447 111.295 84.333  1.00 59.00  ? 512 LEU A HD12 1 
ATOM   7772 H HD13 . LEU A 1 512 ? 124.371 111.739 83.251  1.00 59.00  ? 512 LEU A HD13 1 
ATOM   7773 H HD21 . LEU A 1 512 ? 124.425 114.588 84.453  1.00 59.00  ? 512 LEU A HD21 1 
ATOM   7774 H HD22 . LEU A 1 512 ? 123.066 113.986 83.894  1.00 59.00  ? 512 LEU A HD22 1 
ATOM   7775 H HD23 . LEU A 1 512 ? 123.163 114.454 85.410  1.00 59.00  ? 512 LEU A HD23 1 
ATOM   7776 N N    . LEU A 1 513 ? 123.361 109.792 88.160  1.00 57.52  ? 513 LEU A N    1 
ATOM   7777 C CA   . LEU A 1 513 ? 124.045 109.768 89.447  1.00 57.52  ? 513 LEU A CA   1 
ATOM   7778 C C    . LEU A 1 513 ? 125.152 108.718 89.422  1.00 57.52  ? 513 LEU A C    1 
ATOM   7779 O O    . LEU A 1 513 ? 124.905 107.578 89.012  1.00 57.52  ? 513 LEU A O    1 
ATOM   7780 C CB   . LEU A 1 513 ? 123.053 109.470 90.567  1.00 57.52  ? 513 LEU A CB   1 
ATOM   7781 C CG   . LEU A 1 513 ? 123.506 109.835 91.980  1.00 57.52  ? 513 LEU A CG   1 
ATOM   7782 C CD1  . LEU A 1 513 ? 123.799 111.322 92.092  1.00 57.52  ? 513 LEU A CD1  1 
ATOM   7783 C CD2  . LEU A 1 513 ? 122.454 109.426 92.993  1.00 57.52  ? 513 LEU A CD2  1 
ATOM   7784 H H    . LEU A 1 513 ? 122.568 109.460 88.171  1.00 57.52  ? 513 LEU A H    1 
ATOM   7785 H HA   . LEU A 1 513 ? 124.426 110.642 89.602  1.00 57.52  ? 513 LEU A HA   1 
ATOM   7786 H HB2  . LEU A 1 513 ? 122.235 109.960 90.389  1.00 57.52  ? 513 LEU A HB2  1 
ATOM   7787 H HB3  . LEU A 1 513 ? 122.865 108.518 90.561  1.00 57.52  ? 513 LEU A HB3  1 
ATOM   7788 H HG   . LEU A 1 513 ? 124.323 109.352 92.184  1.00 57.52  ? 513 LEU A HG   1 
ATOM   7789 H HD11 . LEU A 1 513 ? 123.912 111.550 93.028  1.00 57.52  ? 513 LEU A HD11 1 
ATOM   7790 H HD12 . LEU A 1 513 ? 124.613 111.524 91.604  1.00 57.52  ? 513 LEU A HD12 1 
ATOM   7791 H HD13 . LEU A 1 513 ? 123.055 111.819 91.718  1.00 57.52  ? 513 LEU A HD13 1 
ATOM   7792 H HD21 . LEU A 1 513 ? 122.762 109.666 93.881  1.00 57.52  ? 513 LEU A HD21 1 
ATOM   7793 H HD22 . LEU A 1 513 ? 121.627 109.892 92.793  1.00 57.52  ? 513 LEU A HD22 1 
ATOM   7794 H HD23 . LEU A 1 513 ? 122.318 108.468 92.937  1.00 57.52  ? 513 LEU A HD23 1 
ATOM   7795 N N    . PRO A 1 514 ? 126.374 109.050 89.845  1.00 60.03  ? 514 PRO A N    1 
ATOM   7796 C CA   . PRO A 1 514 ? 127.458 108.061 89.788  1.00 60.03  ? 514 PRO A CA   1 
ATOM   7797 C C    . PRO A 1 514 ? 127.164 106.842 90.650  1.00 60.03  ? 514 PRO A C    1 
ATOM   7798 O O    . PRO A 1 514 ? 126.523 106.933 91.698  1.00 60.03  ? 514 PRO A O    1 
ATOM   7799 C CB   . PRO A 1 514 ? 128.674 108.833 90.312  1.00 60.03  ? 514 PRO A CB   1 
ATOM   7800 C CG   . PRO A 1 514 ? 128.340 110.262 90.109  1.00 60.03  ? 514 PRO A CG   1 
ATOM   7801 C CD   . PRO A 1 514 ? 126.861 110.366 90.293  1.00 60.03  ? 514 PRO A CD   1 
ATOM   7802 H HA   . PRO A 1 514 ? 127.619 107.781 88.873  1.00 60.03  ? 514 PRO A HA   1 
ATOM   7803 H HB2  . PRO A 1 514 ? 128.805 108.640 91.253  1.00 60.03  ? 514 PRO A HB2  1 
ATOM   7804 H HB3  . PRO A 1 514 ? 129.462 108.589 89.799  1.00 60.03  ? 514 PRO A HB3  1 
ATOM   7805 H HG2  . PRO A 1 514 ? 128.805 110.799 90.770  1.00 60.03  ? 514 PRO A HG2  1 
ATOM   7806 H HG3  . PRO A 1 514 ? 128.592 110.531 89.212  1.00 60.03  ? 514 PRO A HG3  1 
ATOM   7807 H HD2  . PRO A 1 514 ? 126.645 110.508 91.228  1.00 60.03  ? 514 PRO A HD2  1 
ATOM   7808 H HD3  . PRO A 1 514 ? 126.509 111.074 89.733  1.00 60.03  ? 514 PRO A HD3  1 
ATOM   7809 N N    . GLU A 1 515 ? 127.649 105.691 90.192  1.00 60.53  ? 515 GLU A N    1 
ATOM   7810 C CA   . GLU A 1 515 ? 127.448 104.439 90.906  1.00 60.53  ? 515 GLU A CA   1 
ATOM   7811 C C    . GLU A 1 515 ? 128.410 104.329 92.083  1.00 60.53  ? 515 GLU A C    1 
ATOM   7812 O O    . GLU A 1 515 ? 129.506 104.895 92.073  1.00 60.53  ? 515 GLU A O    1 
ATOM   7813 C CB   . GLU A 1 515 ? 127.638 103.248 89.963  1.00 60.53  ? 515 GLU A CB   1 
ATOM   7814 C CG   . GLU A 1 515 ? 129.043 103.115 89.378  1.00 60.53  ? 515 GLU A CG   1 
ATOM   7815 C CD   . GLU A 1 515 ? 130.001 102.369 90.289  1.00 60.53  ? 515 GLU A CD   1 
ATOM   7816 O OE1  . GLU A 1 515 ? 129.543 101.797 91.301  1.00 60.53  ? 515 GLU A OE1  1 
ATOM   7817 O OE2  . GLU A 1 515 ? 131.214 102.356 89.993  1.00 60.53  ? 515 GLU A OE2  1 
ATOM   7818 H H    . GLU A 1 515 ? 128.099 105.612 89.464  1.00 60.53  ? 515 GLU A H    1 
ATOM   7819 H HA   . GLU A 1 515 ? 126.543 104.410 91.252  1.00 60.53  ? 515 GLU A HA   1 
ATOM   7820 H HB2  . GLU A 1 515 ? 127.436 102.432 90.446  1.00 60.53  ? 515 GLU A HB2  1 
ATOM   7821 H HB3  . GLU A 1 515 ? 127.022 103.345 89.220  1.00 60.53  ? 515 GLU A HB3  1 
ATOM   7822 H HG2  . GLU A 1 515 ? 128.989 102.629 88.540  1.00 60.53  ? 515 GLU A HG2  1 
ATOM   7823 H HG3  . GLU A 1 515 ? 129.407 104.000 89.223  1.00 60.53  ? 515 GLU A HG3  1 
ATOM   7824 N N    . THR A 1 516 ? 127.985 103.583 93.108  1.00 59.62  ? 516 THR A N    1 
ATOM   7825 C CA   . THR A 1 516 ? 128.783 103.402 94.316  1.00 59.62  ? 516 THR A CA   1 
ATOM   7826 C C    . THR A 1 516 ? 128.918 101.932 94.701  1.00 59.62  ? 516 THR A C    1 
ATOM   7827 O O    . THR A 1 516 ? 129.099 101.624 95.883  1.00 59.62  ? 516 THR A O    1 
ATOM   7828 C CB   . THR A 1 516 ? 128.181 104.191 95.481  1.00 59.62  ? 516 THR A CB   1 
ATOM   7829 O OG1  . THR A 1 516 ? 126.910 103.635 95.835  1.00 59.62  ? 516 THR A OG1  1 
ATOM   7830 C CG2  . THR A 1 516 ? 127.998 105.648 95.099  1.00 59.62  ? 516 THR A CG2  1 
ATOM   7831 H H    . THR A 1 516 ? 127.232 103.170 93.124  1.00 59.62  ? 516 THR A H    1 
ATOM   7832 H HA   . THR A 1 516 ? 129.675 103.747 94.158  1.00 59.62  ? 516 THR A HA   1 
ATOM   7833 H HB   . THR A 1 516 ? 128.779 104.146 96.242  1.00 59.62  ? 516 THR A HB   1 
ATOM   7834 H HG1  . THR A 1 516 ? 126.562 104.083 96.454  1.00 59.62  ? 516 THR A HG1  1 
ATOM   7835 H HG21 . THR A 1 516 ? 127.681 106.154 95.864  1.00 59.62  ? 516 THR A HG21 1 
ATOM   7836 H HG22 . THR A 1 516 ? 128.842 106.022 94.803  1.00 59.62  ? 516 THR A HG22 1 
ATOM   7837 H HG23 . THR A 1 516 ? 127.350 105.725 94.381  1.00 59.62  ? 516 THR A HG23 1 
ATOM   7838 N N    . LYS A 1 517 ? 128.836 101.020 93.736  1.00 60.52  ? 517 LYS A N    1 
ATOM   7839 C CA   . LYS A 1 517 ? 128.935 99.592  94.025  1.00 60.52  ? 517 LYS A CA   1 
ATOM   7840 C C    . LYS A 1 517 ? 130.352 99.257  94.476  1.00 60.52  ? 517 LYS A C    1 
ATOM   7841 O O    . LYS A 1 517 ? 131.300 99.351  93.691  1.00 60.52  ? 517 LYS A O    1 
ATOM   7842 C CB   . LYS A 1 517 ? 128.552 98.779  92.792  1.00 60.52  ? 517 LYS A CB   1 
ATOM   7843 C CG   . LYS A 1 517 ? 128.708 97.273  92.966  1.00 60.52  ? 517 LYS A CG   1 
ATOM   7844 C CD   . LYS A 1 517 ? 128.192 96.505  91.756  1.00 60.52  ? 517 LYS A CD   1 
ATOM   7845 C CE   . LYS A 1 517 ? 129.045 96.738  90.518  1.00 60.52  ? 517 LYS A CE   1 
ATOM   7846 N NZ   . LYS A 1 517 ? 130.445 96.269  90.701  1.00 60.52  ? 517 LYS A NZ   1 
ATOM   7847 H H    . LYS A 1 517 ? 128.723 101.202 92.903  1.00 60.52  ? 517 LYS A H    1 
ATOM   7848 H HA   . LYS A 1 517 ? 128.325 99.362  94.740  1.00 60.52  ? 517 LYS A HA   1 
ATOM   7849 H HB2  . LYS A 1 517 ? 127.624 98.957  92.576  1.00 60.52  ? 517 LYS A HB2  1 
ATOM   7850 H HB3  . LYS A 1 517 ? 129.119 99.054  92.055  1.00 60.52  ? 517 LYS A HB3  1 
ATOM   7851 H HG2  . LYS A 1 517 ? 129.647 97.058  93.082  1.00 60.52  ? 517 LYS A HG2  1 
ATOM   7852 H HG3  . LYS A 1 517 ? 128.202 96.989  93.744  1.00 60.52  ? 517 LYS A HG3  1 
ATOM   7853 H HD2  . LYS A 1 517 ? 128.203 95.555  91.955  1.00 60.52  ? 517 LYS A HD2  1 
ATOM   7854 H HD3  . LYS A 1 517 ? 127.288 96.794  91.558  1.00 60.52  ? 517 LYS A HD3  1 
ATOM   7855 H HE2  . LYS A 1 517 ? 128.661 96.249  89.774  1.00 60.52  ? 517 LYS A HE2  1 
ATOM   7856 H HE3  . LYS A 1 517 ? 129.067 97.686  90.315  1.00 60.52  ? 517 LYS A HE3  1 
ATOM   7857 H HZ1  . LYS A 1 517 ? 130.901 96.373  89.944  1.00 60.52  ? 517 LYS A HZ1  1 
ATOM   7858 H HZ2  . LYS A 1 517 ? 130.843 96.738  91.345  1.00 60.52  ? 517 LYS A HZ2  1 
ATOM   7859 H HZ3  . LYS A 1 517 ? 130.450 95.407  90.925  1.00 60.52  ? 517 LYS A HZ3  1 
ATOM   7860 N N    . GLY A 1 518 ? 130.499 98.864  95.738  1.00 58.53  ? 518 GLY A N    1 
ATOM   7861 C CA   . GLY A 1 518 ? 131.769 98.366  96.228  1.00 58.53  ? 518 GLY A CA   1 
ATOM   7862 C C    . GLY A 1 518 ? 132.921 99.341  96.097  1.00 58.53  ? 518 GLY A C    1 
ATOM   7863 O O    . GLY A 1 518 ? 133.997 98.972  95.619  1.00 58.53  ? 518 GLY A O    1 
ATOM   7864 H H    . GLY A 1 518 ? 129.874 98.879  96.329  1.00 58.53  ? 518 GLY A H    1 
ATOM   7865 H HA2  . GLY A 1 518 ? 131.678 98.133  97.165  1.00 58.53  ? 518 GLY A HA2  1 
ATOM   7866 H HA3  . GLY A 1 518 ? 132.002 97.561  95.739  1.00 58.53  ? 518 GLY A HA3  1 
ATOM   7867 N N    . VAL A 1 519 ? 132.712 100.587 96.511  1.00 60.71  ? 519 VAL A N    1 
ATOM   7868 C CA   . VAL A 1 519 ? 133.756 101.604 96.515  1.00 60.71  ? 519 VAL A CA   1 
ATOM   7869 C C    . VAL A 1 519 ? 133.780 102.258 97.888  1.00 60.71  ? 519 VAL A C    1 
ATOM   7870 O O    . VAL A 1 519 ? 132.727 102.622 98.425  1.00 60.71  ? 519 VAL A O    1 
ATOM   7871 C CB   . VAL A 1 519 ? 133.536 102.658 95.413  1.00 60.71  ? 519 VAL A CB   1 
ATOM   7872 C CG1  . VAL A 1 519 ? 132.177 103.322 95.568  1.00 60.71  ? 519 VAL A CG1  1 
ATOM   7873 C CG2  . VAL A 1 519 ? 134.648 103.694 95.443  1.00 60.71  ? 519 VAL A CG2  1 
ATOM   7874 H H    . VAL A 1 519 ? 131.955 100.874 96.803  1.00 60.71  ? 519 VAL A H    1 
ATOM   7875 H HA   . VAL A 1 519 ? 134.617 101.183 96.364  1.00 60.71  ? 519 VAL A HA   1 
ATOM   7876 H HB   . VAL A 1 519 ? 133.558 102.220 94.548  1.00 60.71  ? 519 VAL A HB   1 
ATOM   7877 H HG11 . VAL A 1 519 ? 132.016 103.889 94.798  1.00 60.71  ? 519 VAL A HG11 1 
ATOM   7878 H HG12 . VAL A 1 519 ? 131.492 102.637 95.621  1.00 60.71  ? 519 VAL A HG12 1 
ATOM   7879 H HG13 . VAL A 1 519 ? 132.175 103.856 96.377  1.00 60.71  ? 519 VAL A HG13 1 
ATOM   7880 H HG21 . VAL A 1 519 ? 134.602 104.227 94.634  1.00 60.71  ? 519 VAL A HG21 1 
ATOM   7881 H HG22 . VAL A 1 519 ? 134.531 104.263 96.220  1.00 60.71  ? 519 VAL A HG22 1 
ATOM   7882 H HG23 . VAL A 1 519 ? 135.502 103.238 95.489  1.00 60.71  ? 519 VAL A HG23 1 
ATOM   7883 N N    . ALA A 1 520 ? 134.976 102.403 98.454  1.00 63.41  ? 520 ALA A N    1 
ATOM   7884 C CA   . ALA A 1 520 ? 135.111 102.987 99.781  1.00 63.41  ? 520 ALA A CA   1 
ATOM   7885 C C    . ALA A 1 520 ? 134.510 104.385 99.809  1.00 63.41  ? 520 ALA A C    1 
ATOM   7886 O O    . ALA A 1 520 ? 134.778 105.207 98.929  1.00 63.41  ? 520 ALA A O    1 
ATOM   7887 C CB   . ALA A 1 520 ? 136.583 103.035 100.187 1.00 63.41  ? 520 ALA A CB   1 
ATOM   7888 H H    . ALA A 1 520 ? 135.720 102.171 98.090  1.00 63.41  ? 520 ALA A H    1 
ATOM   7889 H HA   . ALA A 1 520 ? 134.635 102.437 100.423 1.00 63.41  ? 520 ALA A HA   1 
ATOM   7890 H HB1  . ALA A 1 520 ? 136.654 103.432 101.069 1.00 63.41  ? 520 ALA A HB1  1 
ATOM   7891 H HB2  . ALA A 1 520 ? 136.935 102.131 100.202 1.00 63.41  ? 520 ALA A HB2  1 
ATOM   7892 H HB3  . ALA A 1 520 ? 137.071 103.570 99.542  1.00 63.41  ? 520 ALA A HB3  1 
ATOM   7893 N N    . LEU A 1 521 ? 133.696 104.653 100.824 1.00 59.49  ? 521 LEU A N    1 
ATOM   7894 C CA   . LEU A 1 521 ? 133.031 105.943 100.910 1.00 59.49  ? 521 LEU A CA   1 
ATOM   7895 C C    . LEU A 1 521 ? 134.066 107.051 101.096 1.00 59.49  ? 521 LEU A C    1 
ATOM   7896 O O    . LEU A 1 521 ? 135.074 106.851 101.783 1.00 59.49  ? 521 LEU A O    1 
ATOM   7897 C CB   . LEU A 1 521 ? 132.019 105.963 102.058 1.00 59.49  ? 521 LEU A CB   1 
ATOM   7898 C CG   . LEU A 1 521 ? 132.522 105.892 103.500 1.00 59.49  ? 521 LEU A CG   1 
ATOM   7899 C CD1  . LEU A 1 521 ? 131.364 106.132 104.451 1.00 59.49  ? 521 LEU A CD1  1 
ATOM   7900 C CD2  . LEU A 1 521 ? 133.182 104.557 103.806 1.00 59.49  ? 521 LEU A CD2  1 
ATOM   7901 H H    . LEU A 1 521 ? 133.509 104.104 101.456 1.00 59.49  ? 521 LEU A H    1 
ATOM   7902 H HA   . LEU A 1 521 ? 132.553 106.100 100.082 1.00 59.49  ? 521 LEU A HA   1 
ATOM   7903 H HB2  . LEU A 1 521 ? 131.509 106.785 101.982 1.00 59.49  ? 521 LEU A HB2  1 
ATOM   7904 H HB3  . LEU A 1 521 ? 131.420 105.211 101.934 1.00 59.49  ? 521 LEU A HB3  1 
ATOM   7905 H HG   . LEU A 1 521 ? 133.178 106.591 103.644 1.00 59.49  ? 521 LEU A HG   1 
ATOM   7906 H HD11 . LEU A 1 521 ? 131.703 106.169 105.359 1.00 59.49  ? 521 LEU A HD11 1 
ATOM   7907 H HD12 . LEU A 1 521 ? 130.938 106.972 104.221 1.00 59.49  ? 521 LEU A HD12 1 
ATOM   7908 H HD13 . LEU A 1 521 ? 130.728 105.405 104.363 1.00 59.49  ? 521 LEU A HD13 1 
ATOM   7909 H HD21 . LEU A 1 521 ? 133.240 104.447 104.768 1.00 59.49  ? 521 LEU A HD21 1 
ATOM   7910 H HD22 . LEU A 1 521 ? 132.646 103.845 103.424 1.00 59.49  ? 521 LEU A HD22 1 
ATOM   7911 H HD23 . LEU A 1 521 ? 134.071 104.547 103.418 1.00 59.49  ? 521 LEU A HD23 1 
ATOM   7912 N N    . PRO A 1 522 ? 133.853 108.223 100.502 1.00 63.81  ? 522 PRO A N    1 
ATOM   7913 C CA   . PRO A 1 522 ? 134.895 109.252 100.509 1.00 63.81  ? 522 PRO A CA   1 
ATOM   7914 C C    . PRO A 1 522 ? 135.072 109.880 101.879 1.00 63.81  ? 522 PRO A C    1 
ATOM   7915 O O    . PRO A 1 522 ? 134.170 109.865 102.720 1.00 63.81  ? 522 PRO A O    1 
ATOM   7916 C CB   . PRO A 1 522 ? 134.378 110.276 99.495  1.00 63.81  ? 522 PRO A CB   1 
ATOM   7917 C CG   . PRO A 1 522 ? 132.904 110.150 99.580  1.00 63.81  ? 522 PRO A CG   1 
ATOM   7918 C CD   . PRO A 1 522 ? 132.625 108.694 99.841  1.00 63.81  ? 522 PRO A CD   1 
ATOM   7919 H HA   . PRO A 1 522 ? 135.740 108.887 100.203 1.00 63.81  ? 522 PRO A HA   1 
ATOM   7920 H HB2  . PRO A 1 522 ? 134.667 111.167 99.749  1.00 63.81  ? 522 PRO A HB2  1 
ATOM   7921 H HB3  . PRO A 1 522 ? 134.695 110.049 98.607  1.00 63.81  ? 522 PRO A HB3  1 
ATOM   7922 H HG2  . PRO A 1 522 ? 132.573 110.697 100.310 1.00 63.81  ? 522 PRO A HG2  1 
ATOM   7923 H HG3  . PRO A 1 522 ? 132.506 110.427 98.740  1.00 63.81  ? 522 PRO A HG3  1 
ATOM   7924 H HD2  . PRO A 1 522 ? 131.862 108.596 100.433 1.00 63.81  ? 522 PRO A HD2  1 
ATOM   7925 H HD3  . PRO A 1 522 ? 132.489 108.221 99.005  1.00 63.81  ? 522 PRO A HD3  1 
ATOM   7926 N N    . GLU A 1 523 ? 136.264 110.435 102.095 1.00 69.17  ? 523 GLU A N    1 
ATOM   7927 C CA   . GLU A 1 523 ? 136.574 111.169 103.313 1.00 69.17  ? 523 GLU A CA   1 
ATOM   7928 C C    . GLU A 1 523 ? 137.102 112.571 103.041 1.00 69.17  ? 523 GLU A C    1 
ATOM   7929 O O    . GLU A 1 523 ? 137.381 113.305 103.995 1.00 69.17  ? 523 GLU A O    1 
ATOM   7930 C CB   . GLU A 1 523 ? 137.592 110.393 104.164 1.00 69.17  ? 523 GLU A CB   1 
ATOM   7931 C CG   . GLU A 1 523 ? 138.950 110.166 103.503 1.00 69.17  ? 523 GLU A CG   1 
ATOM   7932 C CD   . GLU A 1 523 ? 138.906 109.131 102.393 1.00 69.17  ? 523 GLU A CD   1 
ATOM   7933 O OE1  . GLU A 1 523 ? 137.792 108.722 102.004 1.00 69.17  ? 523 GLU A OE1  1 
ATOM   7934 O OE2  . GLU A 1 523 ? 139.985 108.727 101.911 1.00 69.17  ? 523 GLU A OE2  1 
ATOM   7935 H H    . GLU A 1 523 ? 136.916 110.402 101.537 1.00 69.17  ? 523 GLU A H    1 
ATOM   7936 H HA   . GLU A 1 523 ? 135.763 111.258 103.833 1.00 69.17  ? 523 GLU A HA   1 
ATOM   7937 H HB2  . GLU A 1 523 ? 137.746 110.887 104.984 1.00 69.17  ? 523 GLU A HB2  1 
ATOM   7938 H HB3  . GLU A 1 523 ? 137.219 109.523 104.374 1.00 69.17  ? 523 GLU A HB3  1 
ATOM   7939 H HG2  . GLU A 1 523 ? 139.265 111.000 103.121 1.00 69.17  ? 523 GLU A HG2  1 
ATOM   7940 H HG3  . GLU A 1 523 ? 139.576 109.854 104.174 1.00 69.17  ? 523 GLU A HG3  1 
ATOM   7941 N N    . THR A 1 524 ? 137.247 112.963 101.777 1.00 70.18  ? 524 THR A N    1 
ATOM   7942 C CA   . THR A 1 524 ? 137.737 114.285 101.414 1.00 70.18  ? 524 THR A CA   1 
ATOM   7943 C C    . THR A 1 524 ? 136.887 114.824 100.276 1.00 70.18  ? 524 THR A C    1 
ATOM   7944 O O    . THR A 1 524 ? 136.627 114.109 99.304  1.00 70.18  ? 524 THR A O    1 
ATOM   7945 C CB   . THR A 1 524 ? 139.209 114.236 100.991 1.00 70.18  ? 524 THR A CB   1 
ATOM   7946 O OG1  . THR A 1 524 ? 140.011 113.789 102.091 1.00 70.18  ? 524 THR A OG1  1 
ATOM   7947 C CG2  . THR A 1 524 ? 139.687 115.608 100.537 1.00 70.18  ? 524 THR A CG2  1 
ATOM   7948 H H    . THR A 1 524 ? 137.064 112.468 101.098 1.00 70.18  ? 524 THR A H    1 
ATOM   7949 H HA   . THR A 1 524 ? 137.653 114.885 102.171 1.00 70.18  ? 524 THR A HA   1 
ATOM   7950 H HB   . THR A 1 524 ? 139.309 113.618 100.250 1.00 70.18  ? 524 THR A HB   1 
ATOM   7951 H HG1  . THR A 1 524 ? 140.810 113.700 101.847 1.00 70.18  ? 524 THR A HG1  1 
ATOM   7952 H HG21 . THR A 1 524 ? 140.656 115.622 100.493 1.00 70.18  ? 524 THR A HG21 1 
ATOM   7953 H HG22 . THR A 1 524 ? 139.331 115.811 99.658  1.00 70.18  ? 524 THR A HG22 1 
ATOM   7954 H HG23 . THR A 1 524 ? 139.391 116.287 101.164 1.00 70.18  ? 524 THR A HG23 1 
ATOM   7955 N N    . ILE A 1 525 ? 136.462 116.085 100.393 1.00 68.60  ? 525 ILE A N    1 
ATOM   7956 C CA   . ILE A 1 525 ? 135.603 116.670 99.366  1.00 68.60  ? 525 ILE A CA   1 
ATOM   7957 C C    . ILE A 1 525 ? 136.286 116.615 98.007  1.00 68.60  ? 525 ILE A C    1 
ATOM   7958 O O    . ILE A 1 525 ? 135.654 116.305 96.990  1.00 68.60  ? 525 ILE A O    1 
ATOM   7959 C CB   . ILE A 1 525 ? 135.212 118.111 99.744  1.00 68.60  ? 525 ILE A CB   1 
ATOM   7960 C CG1  . ILE A 1 525 ? 134.266 118.689 98.691  1.00 68.60  ? 525 ILE A CG1  1 
ATOM   7961 C CG2  . ILE A 1 525 ? 136.445 118.990 99.873  1.00 68.60  ? 525 ILE A CG2  1 
ATOM   7962 C CD1  . ILE A 1 525 ? 133.611 119.984 99.104  1.00 68.60  ? 525 ILE A CD1  1 
ATOM   7963 H H    . ILE A 1 525 ? 136.652 116.610 101.047 1.00 68.60  ? 525 ILE A H    1 
ATOM   7964 H HA   . ILE A 1 525 ? 134.788 116.148 99.308  1.00 68.60  ? 525 ILE A HA   1 
ATOM   7965 H HB   . ILE A 1 525 ? 134.752 118.094 100.598 1.00 68.60  ? 525 ILE A HB   1 
ATOM   7966 H HG12 . ILE A 1 525 ? 134.768 118.860 97.879  1.00 68.60  ? 525 ILE A HG12 1 
ATOM   7967 H HG13 . ILE A 1 525 ? 133.564 118.044 98.513  1.00 68.60  ? 525 ILE A HG13 1 
ATOM   7968 H HG21 . ILE A 1 525 ? 136.184 119.843 100.255 1.00 68.60  ? 525 ILE A HG21 1 
ATOM   7969 H HG22 . ILE A 1 525 ? 137.090 118.556 100.453 1.00 68.60  ? 525 ILE A HG22 1 
ATOM   7970 H HG23 . ILE A 1 525 ? 136.831 119.128 98.994  1.00 68.60  ? 525 ILE A HG23 1 
ATOM   7971 H HD11 . ILE A 1 525 ? 133.011 120.271 98.397  1.00 68.60  ? 525 ILE A HD11 1 
ATOM   7972 H HD12 . ILE A 1 525 ? 133.111 119.837 99.922  1.00 68.60  ? 525 ILE A HD12 1 
ATOM   7973 H HD13 . ILE A 1 525 ? 134.296 120.654 99.249  1.00 68.60  ? 525 ILE A HD13 1 
ATOM   7974 N N    . GLU A 1 526 ? 137.586 116.910 97.966  1.00 72.16  ? 526 GLU A N    1 
ATOM   7975 C CA   . GLU A 1 526 ? 138.316 116.820 96.708  1.00 72.16  ? 526 GLU A CA   1 
ATOM   7976 C C    . GLU A 1 526 ? 138.292 115.396 96.170  1.00 72.16  ? 526 GLU A C    1 
ATOM   7977 O O    . GLU A 1 526 ? 138.133 115.182 94.963  1.00 72.16  ? 526 GLU A O    1 
ATOM   7978 C CB   . GLU A 1 526 ? 139.753 117.307 96.905  1.00 72.16  ? 526 GLU A CB   1 
ATOM   7979 C CG   . GLU A 1 526 ? 140.519 117.555 95.613  1.00 72.16  ? 526 GLU A CG   1 
ATOM   7980 C CD   . GLU A 1 526 ? 141.075 116.284 94.999  1.00 72.16  ? 526 GLU A CD   1 
ATOM   7981 O OE1  . GLU A 1 526 ? 141.145 115.256 95.705  1.00 72.16  ? 526 GLU A OE1  1 
ATOM   7982 O OE2  . GLU A 1 526 ? 141.446 116.315 93.807  1.00 72.16  ? 526 GLU A OE2  1 
ATOM   7983 H H    . GLU A 1 526 ? 138.058 117.161 98.640  1.00 72.16  ? 526 GLU A H    1 
ATOM   7984 H HA   . GLU A 1 526 ? 137.891 117.396 96.053  1.00 72.16  ? 526 GLU A HA   1 
ATOM   7985 H HB2  . GLU A 1 526 ? 139.730 118.143 97.395  1.00 72.16  ? 526 GLU A HB2  1 
ATOM   7986 H HB3  . GLU A 1 526 ? 140.239 116.643 97.419  1.00 72.16  ? 526 GLU A HB3  1 
ATOM   7987 H HG2  . GLU A 1 526 ? 139.922 117.963 94.966  1.00 72.16  ? 526 GLU A HG2  1 
ATOM   7988 H HG3  . GLU A 1 526 ? 141.263 118.149 95.797  1.00 72.16  ? 526 GLU A HG3  1 
ATOM   7989 N N    . ASP A 1 527 ? 138.447 114.406 97.053  1.00 71.84  ? 527 ASP A N    1 
ATOM   7990 C CA   . ASP A 1 527 ? 138.381 113.015 96.618  1.00 71.84  ? 527 ASP A CA   1 
ATOM   7991 C C    . ASP A 1 527 ? 136.996 112.669 96.089  1.00 71.84  ? 527 ASP A C    1 
ATOM   7992 O O    . ASP A 1 527 ? 136.868 111.977 95.073  1.00 71.84  ? 527 ASP A O    1 
ATOM   7993 C CB   . ASP A 1 527 ? 138.756 112.084 97.768  1.00 71.84  ? 527 ASP A CB   1 
ATOM   7994 C CG   . ASP A 1 527 ? 138.648 110.622 97.386  1.00 71.84  ? 527 ASP A CG   1 
ATOM   7995 O OD1  . ASP A 1 527 ? 139.498 110.147 96.604  1.00 71.84  ? 527 ASP A OD1  1 
ATOM   7996 O OD2  . ASP A 1 527 ? 137.709 109.949 97.861  1.00 71.84  ? 527 ASP A OD2  1 
ATOM   7997 H H    . ASP A 1 527 ? 138.588 114.513 97.895  1.00 71.84  ? 527 ASP A H    1 
ATOM   7998 H HA   . ASP A 1 527 ? 139.019 112.879 95.901  1.00 71.84  ? 527 ASP A HA   1 
ATOM   7999 H HB2  . ASP A 1 527 ? 139.674 112.258 98.031  1.00 71.84  ? 527 ASP A HB2  1 
ATOM   8000 H HB3  . ASP A 1 527 ? 138.159 112.245 98.515  1.00 71.84  ? 527 ASP A HB3  1 
ATOM   8001 N N    . ALA A 1 528 ? 135.946 113.133 96.768  1.00 67.40  ? 528 ALA A N    1 
ATOM   8002 C CA   . ALA A 1 528 ? 134.592 112.853 96.309  1.00 67.40  ? 528 ALA A CA   1 
ATOM   8003 C C    . ALA A 1 528 ? 134.296 113.495 94.961  1.00 67.40  ? 528 ALA A C    1 
ATOM   8004 O O    . ALA A 1 528 ? 133.450 112.985 94.220  1.00 67.40  ? 528 ALA A O    1 
ATOM   8005 C CB   . ALA A 1 528 ? 133.575 113.336 97.341  1.00 67.40  ? 528 ALA A CB   1 
ATOM   8006 H H    . ALA A 1 528 ? 135.993 113.605 97.485  1.00 67.40  ? 528 ALA A H    1 
ATOM   8007 H HA   . ALA A 1 528 ? 134.486 111.894 96.211  1.00 67.40  ? 528 ALA A HA   1 
ATOM   8008 H HB1  . ALA A 1 528 ? 132.682 113.148 97.015  1.00 67.40  ? 528 ALA A HB1  1 
ATOM   8009 H HB2  . ALA A 1 528 ? 133.728 112.868 98.177  1.00 67.40  ? 528 ALA A HB2  1 
ATOM   8010 H HB3  . ALA A 1 528 ? 133.687 114.291 97.471  1.00 67.40  ? 528 ALA A HB3  1 
ATOM   8011 N N    . GLU A 1 529 ? 134.972 114.597 94.627  1.00 70.58  ? 529 GLU A N    1 
ATOM   8012 C CA   . GLU A 1 529 ? 134.707 115.266 93.358  1.00 70.58  ? 529 GLU A CA   1 
ATOM   8013 C C    . GLU A 1 529 ? 135.019 114.354 92.179  1.00 70.58  ? 529 GLU A C    1 
ATOM   8014 O O    . GLU A 1 529 ? 134.228 114.258 91.233  1.00 70.58  ? 529 GLU A O    1 
ATOM   8015 C CB   . GLU A 1 529 ? 135.521 116.556 93.268  1.00 70.58  ? 529 GLU A CB   1 
ATOM   8016 H H    . GLU A 1 529 ? 135.578 114.969 95.110  1.00 70.58  ? 529 GLU A H    1 
ATOM   8017 H HA   . GLU A 1 529 ? 133.767 115.500 93.316  1.00 70.58  ? 529 GLU A HA   1 
ATOM   8018 N N    . ASN A 1 530 ? 136.162 113.667 92.219  1.00 72.04  ? 530 ASN A N    1 
ATOM   8019 C CA   . ASN A 1 530 ? 136.562 112.757 91.154  1.00 72.04  ? 530 ASN A CA   1 
ATOM   8020 C C    . ASN A 1 530 ? 136.114 111.326 91.414  1.00 72.04  ? 530 ASN A C    1 
ATOM   8021 O O    . ASN A 1 530 ? 136.775 110.380 90.964  1.00 72.04  ? 530 ASN A O    1 
ATOM   8022 C CB   . ASN A 1 530 ? 138.079 112.810 90.957  1.00 72.04  ? 530 ASN A CB   1 
ATOM   8023 C CG   . ASN A 1 530 ? 138.843 112.485 92.224  1.00 72.04  ? 530 ASN A CG   1 
ATOM   8024 O OD1  . ASN A 1 530 ? 138.531 112.997 93.298  1.00 72.04  ? 530 ASN A OD1  1 
ATOM   8025 N ND2  . ASN A 1 530 ? 139.850 111.626 92.105  1.00 72.04  ? 530 ASN A ND2  1 
ATOM   8026 H H    . ASN A 1 530 ? 136.727 113.715 92.866  1.00 72.04  ? 530 ASN A H    1 
ATOM   8027 H HA   . ASN A 1 530 ? 136.150 113.047 90.325  1.00 72.04  ? 530 ASN A HA   1 
ATOM   8028 H HB2  . ASN A 1 530 ? 138.333 112.166 90.279  1.00 72.04  ? 530 ASN A HB2  1 
ATOM   8029 H HB3  . ASN A 1 530 ? 138.330 113.704 90.676  1.00 72.04  ? 530 ASN A HB3  1 
ATOM   8030 H HD21 . ASN A 1 530 ? 140.313 111.409 92.796  1.00 72.04  ? 530 ASN A HD21 1 
ATOM   8031 H HD22 . ASN A 1 530 ? 140.038 111.287 91.337  1.00 72.04  ? 530 ASN A HD22 1 
ATOM   8032 N N    . LEU A 1 531 ? 135.004 111.140 92.130  1.00 68.61  ? 531 LEU A N    1 
ATOM   8033 C CA   . LEU A 1 531 ? 134.537 109.791 92.427  1.00 68.61  ? 531 LEU A CA   1 
ATOM   8034 C C    . LEU A 1 531 ? 134.213 109.030 91.148  1.00 68.61  ? 531 LEU A C    1 
ATOM   8035 O O    . LEU A 1 531 ? 134.561 107.851 91.013  1.00 68.61  ? 531 LEU A O    1 
ATOM   8036 C CB   . LEU A 1 531 ? 133.316 109.853 93.344  1.00 68.61  ? 531 LEU A CB   1 
ATOM   8037 C CG   . LEU A 1 531 ? 132.843 108.522 93.932  1.00 68.61  ? 531 LEU A CG   1 
ATOM   8038 C CD1  . LEU A 1 531 ? 132.222 108.741 95.301  1.00 68.61  ? 531 LEU A CD1  1 
ATOM   8039 C CD2  . LEU A 1 531 ? 131.853 107.836 93.007  1.00 68.61  ? 531 LEU A CD2  1 
ATOM   8040 H H    . LEU A 1 531 ? 134.512 111.770 92.450  1.00 68.61  ? 531 LEU A H    1 
ATOM   8041 H HA   . LEU A 1 531 ? 135.238 109.308 92.892  1.00 68.61  ? 531 LEU A HA   1 
ATOM   8042 H HB2  . LEU A 1 531 ? 133.526 110.439 94.088  1.00 68.61  ? 531 LEU A HB2  1 
ATOM   8043 H HB3  . LEU A 1 531 ? 132.577 110.227 92.840  1.00 68.61  ? 531 LEU A HB3  1 
ATOM   8044 H HG   . LEU A 1 531 ? 133.608 107.935 94.040  1.00 68.61  ? 531 LEU A HG   1 
ATOM   8045 H HD11 . LEU A 1 531 ? 131.910 107.889 95.646  1.00 68.61  ? 531 LEU A HD11 1 
ATOM   8046 H HD12 . LEU A 1 531 ? 132.892 109.113 95.895  1.00 68.61  ? 531 LEU A HD12 1 
ATOM   8047 H HD13 . LEU A 1 531 ? 131.477 109.356 95.215  1.00 68.61  ? 531 LEU A HD13 1 
ATOM   8048 H HD21 . LEU A 1 531 ? 131.457 107.084 93.475  1.00 68.61  ? 531 LEU A HD21 1 
ATOM   8049 H HD22 . LEU A 1 531 ? 131.161 108.469 92.758  1.00 68.61  ? 531 LEU A HD22 1 
ATOM   8050 H HD23 . LEU A 1 531 ? 132.317 107.523 92.216  1.00 68.61  ? 531 LEU A HD23 1 
ATOM   8051 N N    . GLY A 1 532 ? 133.547 109.687 90.198  1.00 74.44  ? 532 GLY A N    1 
ATOM   8052 C CA   . GLY A 1 532 ? 133.256 109.034 88.933  1.00 74.44  ? 532 GLY A CA   1 
ATOM   8053 C C    . GLY A 1 532 ? 134.505 108.760 88.118  1.00 74.44  ? 532 GLY A C    1 
ATOM   8054 O O    . GLY A 1 532 ? 134.617 107.717 87.467  1.00 74.44  ? 532 GLY A O    1 
ATOM   8055 H H    . GLY A 1 532 ? 133.259 110.494 90.264  1.00 74.44  ? 532 GLY A H    1 
ATOM   8056 H HA2  . GLY A 1 532 ? 132.810 108.190 89.101  1.00 74.44  ? 532 GLY A HA2  1 
ATOM   8057 H HA3  . GLY A 1 532 ? 132.664 109.595 88.408  1.00 74.44  ? 532 GLY A HA3  1 
ATOM   8058 N N    . ARG A 1 533 ? 135.460 109.685 88.142  1.00 79.09  ? 533 ARG A N    1 
ATOM   8059 C CA   . ARG A 1 533 ? 136.695 109.534 87.383  1.00 79.09  ? 533 ARG A CA   1 
ATOM   8060 C C    . ARG A 1 533 ? 137.470 108.306 87.848  1.00 79.09  ? 533 ARG A C    1 
ATOM   8061 O O    . ARG A 1 533 ? 137.410 107.929 89.018  1.00 79.09  ? 533 ARG A O    1 
ATOM   8062 C CB   . ARG A 1 533 ? 137.562 110.785 87.520  1.00 79.09  ? 533 ARG A CB   1 
ATOM   8063 H H    . ARG A 1 533 ? 135.415 110.414 88.594  1.00 79.09  ? 533 ARG A H    1 
ATOM   8064 H HA   . ARG A 1 533 ? 136.478 109.419 86.445  1.00 79.09  ? 533 ARG A HA   1 
HETATM 8065 C C1   . NAG B 2 .   ? 64.482  105.600 111.589 1.00 129.75 ? 1   NAG B C1   1 
HETATM 8066 C C2   . NAG B 2 .   ? 63.761  104.439 112.220 1.00 129.75 ? 1   NAG B C2   1 
HETATM 8067 C C3   . NAG B 2 .   ? 62.434  104.228 111.509 1.00 129.75 ? 1   NAG B C3   1 
HETATM 8068 C C4   . NAG B 2 .   ? 61.647  105.529 111.349 1.00 129.75 ? 1   NAG B C4   1 
HETATM 8069 C C5   . NAG B 2 .   ? 62.523  106.769 111.064 1.00 129.75 ? 1   NAG B C5   1 
HETATM 8070 C C6   . NAG B 2 .   ? 61.854  108.079 111.425 1.00 129.75 ? 1   NAG B C6   1 
HETATM 8071 C C7   . NAG B 2 .   ? 64.111  102.024 112.526 1.00 129.75 ? 1   NAG B C7   1 
HETATM 8072 C C8   . NAG B 2 .   ? 65.080  100.888 112.381 1.00 129.75 ? 1   NAG B C8   1 
HETATM 8073 N N2   . NAG B 2 .   ? 64.565  103.229 112.161 1.00 129.75 ? 1   NAG B N2   1 
HETATM 8074 O O3   . NAG B 2 .   ? 61.661  103.278 112.232 1.00 129.75 ? 1   NAG B O3   1 
HETATM 8075 O O4   . NAG B 2 .   ? 60.810  105.292 110.222 1.00 129.75 ? 1   NAG B O4   1 
HETATM 8076 O O5   . NAG B 2 .   ? 63.758  106.753 111.801 1.00 129.75 ? 1   NAG B O5   1 
HETATM 8077 O O6   . NAG B 2 .   ? 61.147  108.642 110.328 1.00 129.75 ? 1   NAG B O6   1 
HETATM 8078 O O7   . NAG B 2 .   ? 62.968  101.856 112.944 1.00 129.75 ? 1   NAG B O7   1 
HETATM 8079 H H2   . NAG B 2 .   ? 63.583  104.661 113.156 1.00 129.75 ? 1   NAG B H2   1 
HETATM 8080 H H3   . NAG B 2 .   ? 62.615  103.855 110.624 1.00 129.75 ? 1   NAG B H3   1 
HETATM 8081 H H4   . NAG B 2 .   ? 61.103  105.679 112.143 1.00 129.75 ? 1   NAG B H4   1 
HETATM 8082 H H5   . NAG B 2 .   ? 62.711  106.781 110.106 1.00 129.75 ? 1   NAG B H5   1 
HETATM 8083 H H61  . NAG B 2 .   ? 62.545  108.704 111.712 1.00 129.75 ? 1   NAG B H61  1 
HETATM 8084 H H62  . NAG B 2 .   ? 61.236  107.942 112.167 1.00 129.75 ? 1   NAG B H62  1 
HETATM 8085 H H81  . NAG B 2 .   ? 65.934  101.105 112.805 1.00 129.75 ? 1   NAG B H81  1 
HETATM 8086 H H82  . NAG B 2 .   ? 65.228  100.716 111.431 1.00 129.75 ? 1   NAG B H82  1 
HETATM 8087 H H83  . NAG B 2 .   ? 64.696  100.093 112.797 1.00 129.75 ? 1   NAG B H83  1 
HETATM 8088 H HN2  . NAG B 2 .   ? 65.420  103.293 111.853 1.00 129.75 ? 1   NAG B HN2  1 
HETATM 8089 H HO3  . NAG B 2 .   ? 60.802  103.417 112.064 1.00 129.75 ? 1   NAG B HO3  1 
HETATM 8090 H HO6  . NAG B 2 .   ? 60.923  109.479 110.525 1.00 129.75 ? 1   NAG B HO6  1 
HETATM 8091 C C1   . NAG B 2 .   ? 59.501  105.921 110.108 1.00 135.28 ? 2   NAG B C1   1 
HETATM 8092 C C2   . NAG B 2 .   ? 58.446  104.938 110.622 1.00 135.28 ? 2   NAG B C2   1 
HETATM 8093 C C3   . NAG B 2 .   ? 57.061  105.548 110.422 1.00 135.28 ? 2   NAG B C3   1 
HETATM 8094 C C4   . NAG B 2 .   ? 57.003  106.918 111.084 1.00 135.28 ? 2   NAG B C4   1 
HETATM 8095 C C5   . NAG B 2 .   ? 58.173  107.804 110.649 1.00 135.28 ? 2   NAG B C5   1 
HETATM 8096 C C6   . NAG B 2 .   ? 58.268  109.071 111.457 1.00 135.28 ? 2   NAG B C6   1 
HETATM 8097 C C7   . NAG B 2 .   ? 57.737  102.621 110.214 1.00 135.28 ? 2   NAG B C7   1 
HETATM 8098 C C8   . NAG B 2 .   ? 58.004  101.361 109.442 1.00 135.28 ? 2   NAG B C8   1 
HETATM 8099 N N2   . NAG B 2 .   ? 58.555  103.648 109.957 1.00 135.28 ? 2   NAG B N2   1 
HETATM 8100 O O3   . NAG B 2 .   ? 56.062  104.711 110.990 1.00 135.28 ? 2   NAG B O3   1 
HETATM 8101 O O4   . NAG B 2 .   ? 55.766  107.555 110.784 1.00 135.28 ? 2   NAG B O4   1 
HETATM 8102 O O5   . NAG B 2 .   ? 59.419  107.126 110.854 1.00 135.28 ? 2   NAG B O5   1 
HETATM 8103 O O6   . NAG B 2 .   ? 58.071  108.783 112.836 1.00 135.28 ? 2   NAG B O6   1 
HETATM 8104 O O7   . NAG B 2 .   ? 56.826  102.705 111.033 1.00 135.28 ? 2   NAG B O7   1 
HETATM 8105 H H2   . NAG B 2 .   ? 58.588  104.814 111.581 1.00 135.28 ? 2   NAG B H2   1 
HETATM 8106 H H3   . NAG B 2 .   ? 56.887  105.657 109.466 1.00 135.28 ? 2   NAG B H3   1 
HETATM 8107 H H4   . NAG B 2 .   ? 57.071  106.771 112.042 1.00 135.28 ? 2   NAG B H4   1 
HETATM 8108 H H5   . NAG B 2 .   ? 58.080  108.010 109.700 1.00 135.28 ? 2   NAG B H5   1 
HETATM 8109 H H61  . NAG B 2 .   ? 57.563  109.695 111.160 1.00 135.28 ? 2   NAG B H61  1 
HETATM 8110 H H62  . NAG B 2 .   ? 59.134  109.484 111.319 1.00 135.28 ? 2   NAG B H62  1 
HETATM 8111 H H81  . NAG B 2 .   ? 58.731  100.875 109.878 1.00 135.28 ? 2   NAG B H81  1 
HETATM 8112 H H82  . NAG B 2 .   ? 58.275  101.587 108.531 1.00 135.28 ? 2   NAG B H82  1 
HETATM 8113 H H83  . NAG B 2 .   ? 57.203  100.803 109.412 1.00 135.28 ? 2   NAG B H83  1 
HETATM 8114 H HN2  . NAG B 2 .   ? 59.218  103.518 109.340 1.00 135.28 ? 2   NAG B HN2  1 
HETATM 8115 H HO3  . NAG B 2 .   ? 55.367  104.706 110.438 1.00 135.28 ? 2   NAG B HO3  1 
HETATM 8116 H HO4  . NAG B 2 .   ? 55.489  108.009 111.493 1.00 135.28 ? 2   NAG B HO4  1 
HETATM 8117 H HO6  . NAG B 2 .   ? 57.752  109.491 113.266 1.00 135.28 ? 2   NAG B HO6  1 
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